359 results on '"van Hout, Hein P."'
Search Results
52. Prevention of Adverse Health Trajectories in a Vulnerable Elderly Population Through Nurse Home Visits: A Randomized Controlled Trial [ISRCTN05358495]
- Author
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van Hout, Hein P., Jansen, Aaltje P., van Marwijk, Harm W., Pronk, Marieke, Frijters, Dinnus F., and Nijpels, Giel
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- 2010
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53. Stepped-Care Prevention of Anxiety and Depression in Late Life: A Randomized Controlled Trial
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vanʼt Veer-Tazelaar, Petronella J., van Marwijk, Harm W. J., van Oppen, Patricia, van Hout, Hein P. J., van der Horst, Henriëtte E., Cuijpers, Pim, Smit, Filip, and Beekman, Aartjan T. F.
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- 2009
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54. Practical Guidelines for Economic Evaluations Alongside Equivalence Trials
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Bosmans, Judith E., de Bruijne, Martine C., van Hout, Hein P. J., Hermens, Marleen L. M., Adèr, Herman J., and van Tulder, Maurits W.
- Published
- 2008
55. Conversion of STOPP/START version 2 into coded algorithms for software implementation: A multidisciplinary consensus procedure
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MS Geriatrie, Apotheek Opleiding, Huibers, Corlina J A, Sallevelt, Bastiaan T G M, de Groot, Dominique A, Boer, Maarten J, van Campen, Jos P C M, Davids, Cathelijn J, Hugtenburg, Jacqueline G, Vermeulen Windsant-Van den Tweel, Annemieke M A, van Hout, Hein P J, van Marum, Rob J, Meulendijk, Michiel C, MS Geriatrie, Apotheek Opleiding, Huibers, Corlina J A, Sallevelt, Bastiaan T G M, de Groot, Dominique A, Boer, Maarten J, van Campen, Jos P C M, Davids, Cathelijn J, Hugtenburg, Jacqueline G, Vermeulen Windsant-Van den Tweel, Annemieke M A, van Hout, Hein P J, van Marum, Rob J, and Meulendijk, Michiel C
- Published
- 2019
56. Anxiety and the risk of death in older men and women
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VAN HOUT, HEIN P. J., BEEKMAN, AARTJAN T. F., DE BEURS, EDWIN, COMIJS, HANNIE, VAN MARWIJK, HARM, DE HAAN, MARTEN, VAN TILBURG, WILLEM, and DEEG, DORLY J. H.
- Published
- 2004
57. Reviewing the definition of crisis in dementia care
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Vroomen Janet MacNeil, Bosmans Judith E, van Hout Hein PJ, and de Rooij Sophia E
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Crisis ,Dementia care ,Definition ,Operational framework ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background Crisis is a term frequently used in dementia care lacking a standardized definition. This article systematically reviews existing definitions of crisis in dementia care literature to create a standardized definition that can be utilized for research, policy and clinical practice. Methods We systematically searched for articles containing definitions of crisis in the context of dementia care. We created an operational framework of crisis based on retrieved definitions. Recommendations to address crisis situations were reviewed and classified according to care settings. Results Abstracts and titles of 1,113 articles, screened from PubMed and EMBASE, were narrowed down to 27 articles. After review, crisis in dementia was defined as a process where a stressor causes an imbalance requiring an immediate decision to be made which leads to a desired outcome and therefore a resolution of the crisis. If the crisis is not resolved, the cycle continues. Recommendations for resolving crisis involving persons with dementia and their caregivers include awareness therapy after diagnosis and increased contact with general practitioners, case manager consultations, caregiver support and education. Furthermore, nursing home staff should be attuned to the environmental, physical and psychological needs of persons with dementia. Conclusions This is the first article to review the definition of crisis in the context of dementia care. A review of the literature indicated that the definition of a crisis is idiosyncratic. Therefore, it is difficult to prevent or plan for all crises. We used an operational framework to compile types of crisis stressors and recommendations from the crisis literature based on three different perspectives; the person with the dementia, the caregiver and the healthcare providers.
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- 2013
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58. Case-finding of dementia in general practice and effects of subsequent collaborative care; design of a cluster RCT
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van den Dungen Pim, Moll van Charante Eric P, van Marwijk Harm W J, van der Horst Henriëtte E, van de Ven Peter M, and van Hout Hein P J
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Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background In the primary care setting, dementia is often diagnosed relatively late in the disease process. Case finding and proactive collaborative care may have beneficial effects on both patient and informal caregiver by clarifying the cause of cognitive decline and changed behaviour and by enabling support, care planning and access to services. We aim to improve the recognition and diagnosis of individuals with dementia in general practice. In addition to this diagnostic aim, the effects of case finding and subsequent care on the mental health of individuals with dementia and the mental health of their informal carers are explored. Methods and design Design: cluster randomised controlled trial with process evaluation. Participants: 162 individuals ≥ 65 years, in 15 primary care practices, in whom GPs suspect cognitive impairment, but without a dementia diagnosis. Intervention; case finding and collaborative care: 2 trained practice nurses (PNs) invite all patients with suspected cognitive impairment for a brief functional and cognitive screening. If the cognitive tests are supportive of cognitive impairment, individuals are referred to their GP for further evaluation. If dementia is diagnosed, a comprehensive geriatric assessment takes place to identify other relevant geriatric problems that need to be addressed. Furthermore, the team of GP and PN provide information and support. Control: GPs provide care and diagnosis as usual. Main study parameters: after 12 months both groups are compared on: 1) incident dementia (and MCI) diagnoses and 2) patient and caregiver quality of life (QoL-AD; EQ5D) and mental health (MH5; GHQ 12) and caregiver competence to care (SSCQ). The process evaluation concerns facilitating and impeding factors to the implementation of this intervention. These factors are assessed on the care provider level, the care recipient level and on the organisational level. Discussion This study will provide insight into the diagnostic yield and the clinical effects of case finding and collaborative care for individuals with suspected cognitive impairment, compared to usual care. A process evaluation will give insight into the feasibility of this intervention. The first results are expected in the course of 2013. Trial registration NTR3389
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- 2012
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59. Comparing Dutch Case management care models for people with dementia and their caregivers: The design of the COMPAS study
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MacNeil Vroomen Janet, Van Mierlo Lisa D, van de Ven Peter M, Bosmans Judith E, van den Dungen Pim, Meiland Franka J M, Dröes Rose-Marie, Moll van Charante Eric P, van der Horst Henriëtte E, de Rooij Sophia E, and van Hout Hein P J
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Dementia ,Case management ,Design ,Clinical evaluation ,Economic evaluation ,Process evaluation ,Informal caregivers ,Implementation ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Dementia care in the Netherlands is shifting from fragmented, ad hoc care to more coordinated and personalised care. Case management contributes to this shift. The linkage model and a combination of intensive case management and joint agency care models were selected based on their emerging prominence in the Netherlands. It is unclear if these different forms of case management are more effective than usual care in improving or preserving the functioning and well-being at the patient and caregiver level and at the societal cost. The objective of this article is to describe the design of a study comparing these two case management care models against usual care. Clinical and cost outcomes are investigated while care processes and the facilitators and barriers for implementation of these models are considered. Design Mixed methods include a prospective, observational, controlled, cohort study among persons with dementia and their primary informal caregiver in regions of the Netherlands with and without case management including a qualitative process evaluation. Inclusion criteria for the cohort study are: community-dwelling individuals with a dementia diagnosis who are not terminally-ill or anticipate admission to a nursing home within 6 months and with an informal caregiver who speaks fluent Dutch. Person with dementia-informal caregiver dyads are followed for two years. The primary outcome measure is the Neuropsychiatric Inventory for the people with dementia and the General Health Questionnaire for their caregivers. Secondary outcomes include: quality of life and needs assessment in both persons with dementia and caregivers, activity of daily living, competence of care, and number of crises. Costs are measured from a societal perspective using cost diaries. Process indicators measure the quality of care from the participant’s perspective. The qualitative study uses purposive sampling methods to ensure a wide variation of respondents. Semi-structured interviews with stakeholders based on the theoretical model of adaptive implementation are planned. Discussion This study provides relevant insights into care processes, description of two case management models along with clinical and economic data from persons with dementia and caregivers to clarify important differences in two case management care models compared to usual care.
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- 2012
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60. Implementing the chronic care model for frail older adults in the Netherlands: study protocol of ACT (frail older adults: care in transition)
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Muntinga Maaike E, Hoogendijk Emiel O, van Leeuwen Karen M, van Hout Hein PJ, Twisk Jos WR, van der Horst Henriette E, Nijpels Giel, and Jansen Aaltje PD
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Chronic care model ,Frailty ,Elderly ,Primary care ,Stepped wedge cluster randomised controlled clinical trial ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background Care for older adults is facing a number of challenges: health problems are not consistently identified at a timely stage, older adults report a lack of autonomy in their care process, and care systems are often confronted with the need for better coordination between health care professionals. We aim to address these challenges by introducing the geriatric care model, based on the chronic care model, and to evaluate its effects on the quality of life of community-dwelling frail older adults. Methods/design In a 2-year stepped-wedge cluster randomised clinical trial with 6-monthly measurements, the chronic care model will be compared with usual care. The trial will be carried out among 35 primary care practices in two regions in the Netherlands. Per region, practices will be randomly allocated to four allocation arms designating the starting point of the intervention. Participants: 1200 community-dwelling older adults aged 65 or over and their primary informal caregivers. Primary care physicians will identify frail individuals based on a composite definition of frailty and a polypharmacy criterion. Final inclusion criterion: scoring 3 or more on a disability case-finding tool. Intervention: Every 6 months patients will receive a geriatric in-home assessment by a practice nurse, followed by a tailored care plan. Expert teams will manage and train practice nurses. Patients with complex care needs will be reviewed in interdisciplinary consultations. Evaluation: We will perform an effect evaluation, an economic evaluation, and a process evaluation. Primary outcome is quality of life as measured with the Short Form-12 questionnaire. Effect analyses will be based on the “intention-to-treat” principle, using multilevel regression analysis. Cost measurements will be administered continually during the study period. A cost-effectiveness analysis and cost-utility analysis will be conducted comparing mean total costs to functional status, care needs and QALYs. We will investigate the level of implementation, barriers and facilitators to successful implementation and the extent to which the intervention manages to achieve the transition necessary to overcome challenges in elderly care. Discussion This is one of the first studies assessing the effectiveness, cost-effectiveness and implementation process of the chronic care model for frail community-dwelling older adults. Trial registration The Netherlands National Trial Register NTR2160.
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- 2012
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61. The occurrence and persistence of thoughts of suicide, self-harm and death in family caregivers of people with dementia: A longitudinal data analysis over 2 years
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Joling, Karlijn J., O'Dwyer, Siobhan T., Hertogh, Cees M P M, van Hout, Hein P J, General practice, APH - Quality of Care, APH - Aging & Later Life, APH - Digital Health, and APH - Mental Health
- Abstract
Objective: Family caregivers of people with dementia often report high levels of stress and depression, but little is known about those who contemplate suicide or self-harm. This study explores thoughts of suicide, self-harm and death in dementia caregivers and investigates the characteristics that distinguish them from those without such thoughts. Methods: Data were collected every 3 months, for 24 months, from 192 family caregivers of people with dementia living in the Netherlands. Caregivers did not have a clinical depression or anxiety disorder at baseline. Suicide-related thoughts were measured with an item from the Mini International Neuropsychiatric Interview, a diagnostic instrument for DSM-IV mental disorders. Fisher exact, analysis of variance or Kruskal-Wallis tests compared the characteristics of caregivers who had contemplated suicide with two comparison groups. Results: Within 24 months, 76 caregivers reported symptoms of a potential depression and were further assessed for suicidal thoughts. Nine carers (11.8%, 4.7% of the total sample) reported suicidal thoughts with three of those at multiple points. Caregivers with suicidal thoughts had more severe depressive and anxious symptoms, had a lower sense of competence and mastery, felt less happy and experienced more health problems, less family support and more feelings of loneliness than caregivers who had not. Conclusion: Suicidal thoughts are present in dementia caregivers and can persist across the care trajectory. Various psychological and social characteristics significantly distinguish caregivers with suicidal thoughts from those without. More research is needed to enable the identification of high-risk caregivers and provide an evidence base for the development of preventive strategies and interventions.
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- 2018
62. Research Report Better Old in Amsterdam
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La Grouw, Yvonne and Van Hout, Hein P J
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- 2018
63. Eindrapportage Onderzoek Beter Oud in Amsterdam
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La Grouw, Yvonne, Van Hout, Hein P J, and Political Science and Public Administration
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- 2018
64. Barriers in recognising, diagnosing and managing depressive and anxiety disorders as experienced by Family Physicians; a focus group study
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Zitman Frans, van de Lisdonk Eloy, van Hout Hein, van Rijswijk Eric, and van Weel Chris
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Medicine (General) ,R5-920 - Abstract
Abstract Background The recognition and treatment of depressive- and anxiety disorders is not always in line with current standards. The results of programs to improve the quality of care, are not encouraging. Perhaps these programs do not match with the problems experienced in family practice. This study aims to systematically explore how FPs perceive recognition, diagnosis and management of depressive and anxiety disorders. Methods focus group discussions with FPs, qualitative analysis of transcriptions using thematic coding. Results The FPs considered recognising, diagnosing and managing depressive- and anxiety disorders as an important task. They expressed serious doubts about the validity and usefulness of the DSM IV concept of depressive and anxiety disorders in family practice especially because of the high frequency of swift natural recovery. An important barrier was that many patients have difficulties in accepting the diagnosis and treatment with antidepressant drugs. FPs lacked guidance in the assessment of patients' burden. The FPs experienced they had too little time for patient education and counseling. The under capacity of specialised mental health care and its minimal collaboration with FPs were experienced as problematic. Valuable suggestions for solving the problems encountered were made Conclusion Next to serious doubts regarding the diagnostic concept of depressive- and anxiety disorders a number of factors were identified which serve as barriers for suitablemental health care by FPs. These doubts and barriers should be taken into account in future research and in the design of interventions to improve mental health care in family practice.
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- 2009
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65. The cost-effectiveness of a new disease management model for frail elderly living in homes for the elderly, design of a cluster randomized controlled clinical trial
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Ribbe Miel W, Frijters Dinnus H, van Hout Hein PJ, Boorsma Marijke, and Nijpels Giel
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Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background The objective of this article is to describe the design of a study to evaluate the clinical and economic effects of a Disease Management model on functional health, quality of care and quality of life of persons living in homes for the elderly. Methods This study concerns a cluster randomized controlled clinical trial among five intervention homes and five usual care homes in the North-West of the Netherlands with a total of over 500 residents. All persons who are not terminally ill, are able to be interviewed and sign informed consent are included. For cognitively impaired persons family proxies will be approached to provide outcome information. The Disease Management Model consists of several elements: (1) Trained staff carries out a multidimensional assessment of the patients functional health and care needs with the interRAI Long Term Care Facilities instrument (LTCF). Computerization of the LTCF produces immediate identification of problem areas and thereby guides individualized care planning. (2) The assessment outcomes are discussed in a Multidisciplinary Meeting (MM) with the nurse, primary care physician, nursing home physician and Psychotherapist and if necessary other members of the care team. The MM presents individualized care plans to manage or treat modifiable disabilities and risk factors. (3) Consultation by an nursing home physician and psychotherapist is offered to the frailest residents at risk for nursing home admission (according to the interRAI LTCF). Outcome measures are Quality of Care indicators (LTCF based), Quality Adjusted Life Years (Euroqol), Functional health (SF12, COOP-WONCA), Disability (GARS), Patients care satisfaction (QUOTE), hospital and nursing home days and mortality, health care utilization and costs. Discussion This design is unique because no earlier studies were performed to evaluate the effects and costs of this Disease Management Model for disabled persons in homes for the elderly on functional health and quality of care. Trail registration number ISRCTN11076857
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- 2008
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66. (Cost)-effectiveness of family meetings on indicated prevention of anxiety and depressive symptoms and disorders of primary family caregivers of patients with dementia: design of a randomized controlled trial
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Gillissen Freek, Bosmans Judith, Vernooij-Dassen Myrra, van den Berg Bernard, Scheltens Philip, van Hout Hein PJ, Joling Karlijn J, Mittelman Mary, and van Marwijk Harm WJ
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Geriatrics ,RC952-954.6 - Abstract
Abstract Background Dementia is a major public health problem with enormous costs to society and major consequences for both patients and their relatives. Family members of persons with dementia provide much of the care for older adults with dementia in the community. Caring for a demented relative is not easy and fraught with emotional strain, distress, and physical exhaustion. Family caregivers of dementia patients have an extremely high risk developing affective disorders such as major depression and anxiety disorder. Family meetings appear to be among the most powerful psychosocial interventions to reduce depression in caregivers. An American landmark study reported substantial beneficial effects of a multifaceted intervention where family meetings had a central place on depression in family caregivers as well as on delay of institutionalization of patients. These effects were not replicated in other countries yet. We perform the first trial comparing only structured family meetings with significant others versus usual care among primary family caregivers of community dwelling demented patients and measure the effectiveness on both depression and anxiety in the primary caregiver, both on disorder and symptom levels. Methods/design In this randomized controlled trial effectiveness as well as cost-effectiveness of family meetings is evaluated. The intervention group receives four family meetings with family and close friends of the primary family caregiver of a community dwelling patient with a clinical diagnosis of dementia. Dyads of patients and their primary caregiver are followed up to one year after baseline assessment. The main outcome measures are the incidence of anxiety and depressive disorders assessed with the Mini-International Neuropsychiatric Interview (MINI) and the severity of anxiety and depressive symptoms in caregivers is measured by validated self report instruments: the Centre for Epidemiologic Studies Depression Scale (CES-D) for depression and the anxiety scales of the Hospital Anxiety and Depression scales (HADS) for anxiety. The economic evaluation is performed from a societal perspective. Discussion By evaluating the effectiveness of only structured family meetings organized in the Netherlands, this study will contribute to the existing literature about the value of psychosocial interventions for dementia caregivers. Trial registration Dutch Trial Registry ISRCTN90163486
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- 2008
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67. Clinical effectiveness of usual care with or without antidepressant medication for primary care patients with minor or mild-major depression: a randomized equivalence trial
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van Dyck Richard, Bosmans Judith E, van Marwijk Harm WJ, Penninx Brenda WJH, Adèr Herman J, Terluin Berend, van Hout Hein PJ, Hermens Marleen LM, and de Haan Marten
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Medicine - Abstract
Abstract Background Minor and mild-major depression are highly prevalent in primary care. There is insufficient evidence for the effectiveness of antidepressants in the treatment of minor and mild-major depression. We compared the effectiveness of usual primary care treatment, with or without antidepressants, in minor and mild-major depression. Methods A pragmatic patient-randomized equivalence trial with 52 weeks follow-up was conducted in The Netherlands. In total, 59 primary care physicians (PCPs) recruited and treated 181 adult patients with minor or mild-major depression. Patients were randomized to four consultations within 3 months of usual care plus antidepressants (UCandAD) or usual care alone (UCnoAD). The Montgomery Åsberg Depression Rating Scale (MADRS) was used to assess changes in severity of depressive symptoms. The predefined equivalence margin was set at five points. Multilevel analysis was used to analyze the data. Secondary outcome measures were the Short-Form 36 (SF-36), and the Client Satisfaction Questionnaire (CSQ-8). Results Patients received on average 3.0 (SD 1.4) 15-min consultations within 3 months with (n = 85) or without paroxetine (n = 96). Equivalence of UCandAD and UCnoAD was demonstrated in the intention-to-treat analyses as well as the per-protocol analysis after 6 weeks, but not at 13, 26 and 52 weeks follow-up. No statistical differences in effectiveness between treatment groups were found in the intention-to-treat analysis. No differences in the physical and mental functioning (SF-36) were found between the treatment groups. Patients allocated to UCandAD were slightly more satisfied with their treatment at 13 weeks follow-up (but not at 52 weeks follow-up) than patients allocated to UCnoAD. Preliminary analyses suggested that subgroups such as patients with mild-major (instead of a minor) depression might benefit from antidepressant treatment. Patients who were assigned to their preferred treatment (in particular to UCnoAD) were more often compliant and had better clinical outcomes. Conclusion UCandAD was as effective as UCnoAD over the first 6 weeks, but not at 13, 26, and 52 weeks. However, superiority of either treatment could not be demonstrated either. The question whether antidepressants add any clinical effect to usual care remains unresolved. We recommend future studies to look for subgroups of patients who may benefit from antidepressants. Trial registration Dutch Trial Registry ISRCN03007807.
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- 2007
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68. Quality indicators for community care for older people : A systematic review
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Joling, Karlijn J., van Eenoo, Liza, Vetrano, Davide L., Smaardijk, Veerle R., Declercq, Anja, Onder, Graziano, van Hout, Hein P. J., van der Roest, Henriette G., Joling, Karlijn J., van Eenoo, Liza, Vetrano, Davide L., Smaardijk, Veerle R., Declercq, Anja, Onder, Graziano, van Hout, Hein P. J., and van der Roest, Henriette G.
- Abstract
Background Health care systems that succeed in preventing long term care and hospital admissions of frail older people may substantially save on their public spending. The key might be found in high-quality care in the community. Quality Indicators (QIs) of a sufficient methodological level are a prerequisite to monitor, compare, and improve care quality. This systematic review identified existing QIs for community care for older people and assessed their methodological quality. Methods Relevant studies were identified by searches in electronic reference databases and selected by two reviewers independently. Eligible publications described the development or application of QIs to assess the quality of community care for older people. Information about the QIs, the study sample, and specific setting was extracted. The methodological quality of the QI sets was assessed with the Appraisal of Indicators through Research and Evaluation (AIRE) instrument. A score of 50% or higher on a domain was considered to indicate high methodological quality. Results Searches resulted in 25 included articles, describing 17 QI sets with 567 QIs. Most indicators referred to care processes (80%) and measured clinical issues (63%), mainly about follow-up, monitoring, examinations and treatment. About two-third of the QIs focussed on specific disease groups. The methodological quality of the indicator sets varied considerably. The highest overall level was achieved on the domain 'Additional evidence, formulation and usage' (51%), followed by 'Scientific evidence' (39%) and 'Stakeholder involvement' (28%). Conclusion A substantial number of QIs is available to assess the quality of community care for older people. However, generic QIs, measuring care outcomes and non-clinical aspects are relatively scarce and most QI sets do not meet standards of high methodological quality. This study can support policy makers and clinicians to navigate through a large number of QIs and select QIs for thei
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- 2018
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69. Prevention of anxiety and depression in the age group of 75 years and over: a randomised controlled trial testing the feasibility and effectiveness of a generic stepped care programme among elderly community residents at high risk of developing anxiety and depression versus usual care [ISRCTN26474556]
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van Oppen Patricia, van Marwijk Harm, van 't Veer-Tazelaar Nelleke, Nijpels Giel, van Hout Hein, Cuijpers Pim, Stalman Wim, and Beekman Aartjan
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Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background In frail elderly, the effects of depression and anxiety are deep encroaching. Indicated prevention studies, aimed at subjects with subthreshold disorder, have shown that well designed interventions are capable of reducing the incidence of depression and anxiety. In this randomised prevention trial for elderly, living in the community and suffering from subthreshold depression and anxiety, a stepped care programme was put together to be tested versus usual (GP) care. Methods/design Design: randomised controlled trial. (See figure 1: organisation chart) together with two other projects, this project is part of a national consortium that investigates the prevention of anxiety and depressive disorders in later life using a stepped care programme. The three projects have their own particular focus. This project is aimed at elderly living in the community. Inclusion: subjects with a high risk for depression and anxiety without clinical evidence of these syndromes. The participants are 75 years of age and over and have subthreshold symptoms of depression and or anxiety: they score above the cut-off point on the self-report Centre for Epidemiologic Studies Depression (CES-D) scale, but the criteria for a major depressive disorder or anxiety disorder (panic disorder, agoraphobia, social phobia, generalized anxiety disorder) according to a validated interview, the Mini International Neuropsychiatric Interview (MINI) are not fulfilled. Outcomes: primary outcome: incidence of a depressive or anxiety disorder over a period of two years (MINI); secondary outcome: a positive influence of the intervention, a stepped care programme, on symptoms of depression and anxiety and on quality of life as assessed with the CES D, the HADS A and the SF36 respectively (i.e. stabilisation or improvement of symptoms) [see table 1]. Measurements: Take place at baseline and at 3, 6, 9, 12, 18 and 24 months. Trained independent evaluators assess depression and anxiety status, the primary end point (6, 12, 18, 24 months) [see table 2]. Discussion Late-life depression and anxiety are characterised by high prevalence, unfavourable prognosis, reduced quality of life, excess mortality and substantial societal costs. No health service, however well equipped, will be able to effectively treat all elderly with depression and anxiety. Therefore, development of (cost) effective means to prevent these disorders is very important.
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- 2006
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70. Administering the MADRS by telephone or face-to-face: a validity study
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van Dyck Richard, Terluin Berend, van Hout Hein PJ, Adèr Herman J, Hermens Marleen LM, and de Haan Marten
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Psychiatry ,RC435-571 - Abstract
Abstract Background The Montgomery Åsberg Depression Rating Scale (MADRS) is a frequently used observer-rated depression scale. In the present study, a telephonic rating was compared with a face-to-face rating in 66 primary care patients with minor or mild-major depression. The aim of the present study was to assess the validity of the administration by telephone. Additional objective was to study the validity of the first item, 'apparent sadness', the only item purely based on observation. Methods The present study was a validity study. During an in-person interview at the patient's home a trained interviewer administered the MADRS. A few days later the MADRS was administered again, but now by telephone and by a different interviewer. The validity of the telephone rating was calculated through the appropriate intraclass correlation coefficient (ICC). Results Mean total score on the in-person administration was 24.0 (SD = 11.1), and on the telephone administration 23.5 (SD = 10.4). The ICC for the full scale was 0.65. Homogeneity analysis showed that the observation item 'apparent sadness' fitted well into the scale. Conclusion The full MADRS, including the observation item 'apparent sadness', can be administered reliably by telephone.
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- 2006
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71. (Cost)-effectiveness of case-management by district nurses among primary informal caregivers of older adults with dementia symptoms and the older adults who receive informal care: design of a randomized controlled trial [ISCRTN83135728]
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Nijpels Giel, van Marwijk Harm WJ, van Hout Hein PJ, Jansen Aaltje PD, de Bruijne Martine C, Bosmans Judith E, Pot Anne-Margriet, and Stalman Wim AB
- Subjects
Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Dementia is an incurable disease with devastating consequences for both patients and their relatives. The objective of this study is to describe the study protocol of a randomized controlled trial with assignment to either usual care or case-management by district nurses, among informal caregivers of older adults with dementia symptoms who live at home and the older adults who receive informal care. Methods/design In this randomized controlled trial, effectiveness as well as cost-effectiveness of case-management is evaluated. It concerns case-management in early-detected patients with dementia symptoms and their primary informal caregivers. Participants are followed up to twelve months after baseline assessment. The main outcome measure of the effect evaluation is the caregiver's sense of competence to care for the older person with dementia symptoms. The economic evaluation is performed from a societal perspective. Discussion This is one of the first trials on case-management that includes an economic evaluation. In addition, it concerns a tailor-made intervention in early-detected patients with dementia symptoms and their caregivers. The results of this randomized controlled trial will provide valuable information for health professionals and policy makers on effectiveness and cost-effectiveness of early tailor-made case-management for patients and their informal caregivers. Moreover, positive effects will challenge current health care systems to move to more pro-active approaches for this group.
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- 2005
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72. Design and pilot results of a single blind randomized controlled trial of systematic demand-led home visits by nurses to frail elderly persons in primary care [ISRCTN05358495]
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Tybout Willemijn, van't Veer Petronella J, Jansen Aaltje PD, van Marwijk Harm WJ, Nijpels Giel, van Hout Hein PJ, and Stalman Wim AB
- Subjects
Geriatrics ,RC952-954.6 - Abstract
Abstract Background The objective of this article is to describe the design of an evaluation of the cost-effectiveness of systematic home visits by nurses to frail elderly primary care patients. Pilot objectives were: 1. To determine the feasibility of postal multidimensional frailty screening instruments; 2. to identify the need for home visits to elderly. Methods Main study: The main study concerns a randomized controlled in primary care practices (PCP) with 18 months follow-up and blinded PCPs. Frail persons aged 75 years or older and living at home but neither terminally ill nor demented from 33 PCPs were eligible. Trained community nurses (1) visit patients at home and assess the care needs with the Resident Assessment Instrument-Home Care, a multidimensional computerized geriatric assessment instrument, enabling direct identification of problem areas; (2) determine the care priorities together with the patient; (3) design and execute interventions according to protocols; (4) and visit patients at least five times during a year in order to execute and monitor the care-plan. Controls receive usual care. Outcome measures are Quality of life, and Quality Adjusted Life Years; time to nursing home admission; mortality; hospital admissions; health care utilization. Pilot 1: Three brief postal multidimensional screening measures to identify frail health among elderly persons were tested on percentage complete item response (selected after a literature search): 1) Vulnerable Elders Screen, 2) Strawbridge's frailty screen, and 3) COOP-WONCA charts. Pilot 2: Three nurses visited elderly frail patients as identified by PCPs in a health center of 5400 patients and used an assessment protocol to identify psychosocial and medical problems. The needs and experiences of all participants were gathered by semi-structured interviews. Discussion The design holds several unique elements such as early identification of frail persons combined with case-management by nurses. From two pilots we learned that of three potential postal frailty measures, the COOP-WONCA charts were completed best by elderly and that preventive home visits by nurses were positively evaluated to have potential for quality of care improvement.
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- 2005
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73. Everyday functioning in a community‐based volunteer population: Factors associated with concordance between participant and study partner—Report.
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Verrijp, Merike, Dubbelman, Mark A., Visser, Leonie N.C., Jutten, Roos J., Nijhuis, Elke W, Van Hout, Hein PJ, Scheltens, Philip, van der Flier, Wiesje M, and Sikkes, Sietske A.M.
- Abstract
Background: With the shift towards preclinical phases of Alzheimer's disease (AD) and other neurodegenerative diseases in research studies and clinical trials, the question arises if participants can reliably self‐report their level of everyday functioning. Here, we aim to investigate the factors related to concordance between participant‐ and study partner‐report versions of the Amsterdam Instrumental Activities of Daily Living Questionnaire (A‐IADL‐Q) in a community‐based volunteer population. Method: Community based volunteers (participants) and their study partners were recruited from a Dutch brain research registry. IADL concordance between participant and study partner was investigated using intraclass correlation coefficient (ICC). Dyads were subsequently categorized as (1) concordant (<2 points differences in A‐IADL‐Q score); (2) discordant, with study partner reporting more difficulties (study partner>participant) and (3) discordant, participant>study partner. Multinomial logistic regression models were used to investigate the association between subjective cognitive decline, depressive symptoms (Geriatric Depression Scale‐5), type of relationship, objective cognitive functioning (Cognitive Online Self‐Test Amsterdam), and concordance as dependent variable. Result: A total of 1213 participants (18‐93 years of age, 68.3% female) and 1213 study partners (18‐88 years, 45.8% female) completed the A‐IADL‐Q. The majority of participants (52.8%) and study partners (59.5%) reported no IADL difficulties. Figure 1 shows the percentage of IADL difficulty reported for individual activities by both participants and study partners. Of the dyads, 653 (53.8%) were in concordance, with an ICC of.55 (95%CI=[.51,.59], Figure 2). Depressive symptoms and memory complaints increased the odds of participants reporting more IADL difficulties compared to their study partner (odds ratio (OR)=1.31, p<.01 and OR=2.56, p<.01, Table 1). An inverse association was found between A‐IADL‐Q and concordance, to the extent that higher A‐IADL‐Q scores were associated with a lower odds of study partner>participant discordance (OR=0.68, p<.01). Conclusion: A slight majority of dyads showed concordance between participant‐ and study partner‐reported IADL scores. Our findings suggest that concordance is less likely in the presence of memory complaints, depressive symptoms and with lower levels of everyday functioning. These findings implicate that participant‐ and study partner report capture different aspects of functional decline, which might influence the study design of longitudinal aging studies. [ABSTRACT FROM AUTHOR]
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- 2021
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74. Are older long term care residents accurately prognosticated and consequently informed about their prognosis? Results from SHELTER study data in 5 European countries
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ten Koppel, Maud, primary, Onwuteaka-Philipsen, Bregje D., additional, Pasman, H. Roeline, additional, Bernabei, Roberto, additional, Carpenter, Iain, additional, Denkinger, Michael D., additional, Onder, Graziano, additional, van der Roest, Henriëtte G., additional, Topinkova, Eva, additional, and van Hout, Hein P. J., additional
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- 2018
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75. Quality indicators for community care for older people: A systematic review
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Joling, Karlijn J., primary, van Eenoo, Liza, additional, Vetrano, Davide L., additional, Smaardijk, Veerle R., additional, Declercq, Anja, additional, Onder, Graziano, additional, van Hout, Hein P. J., additional, and van der Roest, Henriëtte G., additional
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- 2018
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76. Consensus-based cross-European recommendations for the identification, measurement and valuation of costs in health economic evaluations: a European Delphi study
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van Lier, Lisanne I., primary, Bosmans, Judith E., additional, van Hout, Hein P. J., additional, Mokkink, Lidwine B., additional, van den Hout, Wilbert B., additional, de Wit, G. Ardine, additional, Dirksen, Carmen D., additional, Nies, Henk L. G. R., additional, Hertogh, Cees M. P. M., additional, and van der Roest, Henriëtte G., additional
- Published
- 2017
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77. Implementation and (cost-)effectiveness of case management for people with dementia and their informal caregivers:results of the COMPAS study
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van Mierlo, Lisa D, MacNeil-Vroomen, Janet, Meiland, Franka J M, Joling, Karlijn J, Bosmans, Judith E, Droes, Rose-Marie, Moll van Charante, Eric P, de Rooij, Sophia E J A, van Hout, Hein P J, Other departments, Amsterdam Cardiovascular Sciences, Amsterdam Public Health, General practice, Amsterdam Neuroscience, Other Research, Geriatrics, Health Economics and Health Technology Assessment, EMGO+ - Mental Health, Psychiatry, and EMGO - Quality of care
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Male ,Cost-Benefit Analysis ,Cohort Studies ,Caregivers ,Quality of Life ,Journal Article ,Humans ,Dementia ,Female ,Independent Living ,Case Management ,Aged ,Netherlands ,Quality of Health Care - Abstract
BACKGROUND: Different forms of case management for dementia have emerged over the past few years. In the COMPAS study (Collaborative dementia care for patients and caregivers study), two prominent Dutch case management forms were studied: the linkage and the integrated care form.AIM OF STUDY: Evaluation of the (cost)effectiveness of two dementia case management forms compared to usual care as well as factors that facilitated or impeded their implementation.METHODS: A mixed methods design with a) a prospective, observational controlled cohort study with 2 years follow-up among 521 dyads of people with dementia and their primary informal caregiver with and without case management; b) interviews with 22 stakeholders on facilitating and impeding factors of the implementation and continuity of the two case management models. Outcome measures were severity and frequency of behavioural problems (NPI) for the person with dementia and mental health complaints (GHQ-12) for the informal caregiver, total met and unmet care needs (CANE) and quality adjusted life years (QALYs).RESULTS: Outcomes showed a better quality of life of informal caregivers in the integrated model compared to the linkage model. Caregivers in the control group reported more care needs than those in both case management groups. The independence of the case management provider in the integrated model facilitated the implementation, while the rivalry between multiple providers in the linkage model impeded the implementation. The costs of care were lower in the linkage model (minus 22 %) and integrated care model (minus 33 %) compared to the control group.CONCLUSION: The integrated care form was (very) cost-effective in comparison with the linkage form or no case management. The integrated care form is easy to implement.
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- 2016
78. Evaluation of a Palliative Care Program for Nursing Homes in 7 Countries: The PACE Cluster-Randomized Clinical Trial
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Van den Block, Lieve, Honinx, Elisabeth, Pivodic, Lara, Miranda, Rose, Onwuteaka-Philipsen, Bregje D., van Hout, Hein, Pasman, H. Roeline W., Oosterveld-Vlug, Mariska, Ten Koppel, Maud, Piers, Ruth, Van Den Noortgate, Nele, Engels, Yvonne, Vernooij-Dassen, Myrra, Hockley, Jo, Froggatt, Katherine, Payne, Sheila, Szczerbinska, Katarzyna, Kylänen, Marika, Gambassi, Giovanni, Pautex, Sophie, Bassal, Catherine, De Buysser, Stefanie, Deliens, Luc, and Smets, Tinne
- Abstract
IMPORTANCE: High-quality evidence on how to improve palliative care in nursing homes is lacking. OBJECTIVE: To investigate the effect of the Palliative Care for Older People (PACE) Steps to Success Program on resident and staff outcomes. DESIGN, SETTING, AND PARTICIPANTS: A cluster-randomized clinical trial (2015-2017) in 78 nursing homes in 7 countries comparing PACE Steps to Success Program (intervention) with usual care (control). Randomization was stratified by country and median number of beds in each country in a 1:1 ratio. INTERVENTIONS: The PACE Steps to Success Program is a multicomponent intervention to integrate basic nonspecialist palliative care in nursing homes. Using a train-the-trainer approach, an external trainer supports staff in nursing homes to introduce a palliative care approach over the course of 1 year following a 6-steps program. The steps are (1) advance care planning with residents and family, (2) assessment, care planning, and review of needs and problems, (3) coordination of care via monthly multidisciplinary review meetings, (4) delivery of high-quality care focusing on pain and depression, (5) care in the last days of life, and (6) care after death. MAIN OUTCOMES AND MEASURES: The primary resident outcome was comfort in the last week of life measured after death by staff using the End-of-Life in Dementia Scale Comfort Assessment While Dying (EOLD-CAD; range, 14-42). The primary staff outcome was knowledge of palliative care reported by staff using the Palliative Care Survey (PCS; range, 0-1). RESULTS: Concerning deceased residents, we collected 551 of 610 questionnaires from staff at baseline and 984 of 1178 postintervention in 37 intervention and 36 control homes. Mean (SD) age at time of death ranged between 85.22 (9.13) and 85.91 (8.57) years, and between 60.6% (160/264) and 70.6% (190/269) of residents were women across the different groups. Residents’ comfort in the last week of life did not differ between intervention and control groups (baseline-adjusted mean difference, −0.55; 95% CI, −1.71 to 0.61; P = .35). Concerning staff, we collected 2680 of 3638 questionnaires at baseline and 2437 of 3510 postintervention in 37 intervention and 38 control homes. Mean (SD) age of staff ranged between 42.3 (12.1) and 44.1 (11.7) years, and between 87.2% (1092/1253) and 89% (1224/1375) of staff were women across the different groups. Staff in the intervention group had statistically significantly better knowledge of palliative care than staff in the control group, but the clinical difference was minimal (baseline-adjusted mean difference, 0.04; 95% CI, 0.02-0.05; P < .001). Data analyses began on April 20, 2018. CONCLUSIONS AND RELEVANCE: Residents’ comfort in the last week of life did not improve after introducing the PACE Steps to Success Program. Improvements in staff knowledge of palliative care were clinically not important. TRIAL REGISTRATION: ISRCTN Identifier: ISRCTN14741671
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- 2020
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79. Study partner‐ and self‐reported difficulties in cognitively complex everyday activities in participants without objective cognitive impairment: Epidemiology / Innovative methods in epidemiology (i.e., assessment methods, design,...
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Verrijp, Merike, Dubbelman, Mark A, Nijhuis, Elke W, Visser, Leonie NC, Zwan, Marissa D, Jutten, Roos J, Van Hout, Hein PJ, van Der Flier, Wiesje, Scheltens, Philip, and Sikkes, Sietske AM
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Background: Study partner report is used to assess cognitively complex everyday activities, or instrumental activities of daily living (IADL). Because a study partner is not always available, the question arises whether IADL can also be evaluated using self‐report. The aim of this study is to investigate the relationship between study partner‐ and self‐report IADL in individuals without objective cognitive impairment, and to explore its associated factors. Method: Participants (N=3,295; mean age 61.0±12.1 years, 70.3% female; Table 1.) and their study partners (N=1,225) were recruited from the Dutch Brain Research Registry. They completed self‐ and study partner‐report versions of the Amsterdam IADL Questionnaire. For the 1,225 dyads, linear regression analyses were used to investigate the relationship between self‐ and study partner report. Age, sex, cohabitation, marital status, education and subjective memory complaints were explored as potential confounders and effect‐modifiers. Result: A total of 1,544 (46.9%) participants and study partners (n=497, 40.6%) reported an increased level of difficulty in at least one IADL activity (Figure 1). Absolute agreement between self and study partner on item level was high, ranging from 93.3–99.2%. Participants self‐reported more IADL difficulties (M=65.9±SD=4.7), compared to their study partners (M=66.1±SD=4.6; p<0.05). The study partner‐ and self‐ reported IADL scores were significantly associated (B=0.54). When participants experienced memory complaints, both the participant and study partner reported more IADL difficulties (both p<0.001, Figure 2). Furthermore, we found an interaction effect indicating that the association between self and study partner was lower for those without memory complaints (B= 0.42, Figure 3). In addition, the association between self‐ and proxy was slightly lower for highly educated participants (B=0.47). Conclusion: Subtle difficulties in IADL were present in about half of the population, and a high level of agreement between self and study partner was observed on both item and scale level IADL. We found several factors influencing the level of agreement, and in a next step we will include objective cognitive markers to explore the etiology of these differences. These findings provide support for the use of IADL self‐report in cognitively unimpaired individuals, in particular for use in primary or secondary prevention trials. [ABSTRACT FROM AUTHOR]
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- 2020
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80. The Cost-Effectiveness of Two Forms of Case Management Compared to a Control Group for Persons with Dementia and Their Informal Caregivers from a Societal Perspective
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MacNeil Vroomen, Janet, primary, Bosmans, Judith E., additional, Eekhout, Iris, additional, Joling, Karlijn J., additional, van Mierlo, Lisa D., additional, Meiland, Franka J. M., additional, van Hout, Hein P. J., additional, and de Rooij, Sophia E., additional
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- 2016
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81. Convergent validity of the interRAI-HC for societal costs estimates in comparison with the RUD Lite instrument in community dwelling older adults
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van Lier, Lisanne I., primary, van der Roest, Henriëtte G., additional, van Hout, Hein P. J., additional, van Eenoo, Liza, additional, Declercq, Anja, additional, Garms-Homolová, Vjenka, additional, Onder, Graziano, additional, Finne-Soveri, Harriet, additional, Jónsson, Pálmi V., additional, Hertogh, Cees M. P. M., additional, and Bosmans, Judith. E., additional
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- 2016
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82. Comparison of 10 single and stepped methods to identify frail older persons in primary care: diagnostic and prognostic accuracy
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Sutorius, Fleur L., primary, Hoogendijk, Emiel O., additional, Prins, Bernard A. H., additional, and van Hout, Hein P. J., additional
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- 2016
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83. Case Finding of Mild Cognitive Impairment and Dementia and Subsequent Care; Results of a Cluster RCT in Primary Care
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van den Dungen, Pim, primary, Moll van Charante, Eric P., additional, van de Ven, Peter M., additional, van Marwijk, Harm W. J., additional, van der Horst, Henriëtte E., additional, and van Hout, Hein P. J., additional
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- 2016
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84. Interactions between drugs and geriatric syndromes in nursing home and home care: results from Shelter and IBenC projects.
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Onder, Graziano, Giovannini, Silvia, Sganga, Federica, Manes-Gravina, Ester, Topinkova, Eva, Finne-Soveri, Harriet, Garms-Homolová, Vjenka, Declercq, Anja, van der Roest, Henriëtte G., Jónsson, Pálmi V., van Hout, Hein, and Bernabei, Roberto
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Aim: Drugs may interact with geriatric syndromes by playing a role in the continuation, recurrence or worsening of these conditions. Aim of this study is to assess the prevalence of interactions between drugs and three common geriatric syndromes (delirium, falls and urinary incontinence) among older adults in nursing home and home care in Europe.Methods: We performed a cross-sectional multicenter study among 4023 nursing home residents participating in the Services and Health for Elderly in Long-TERm care (Shelter) project and 1469 home care patients participating in the Identifying best practices for care-dependent elderly by Benchmarking Costs and outcomes of community care (IBenC) project. Exposure to interactions between drugs and geriatric syndromes was assessed by 2015 Beers criteria.Results: 790/4023 (19.6%) residents in the Shelter Project and 179/1469 (12.2%) home care patients in the IBenC Project presented with one or more drug interactions with geriatric syndromes. In the Shelter project, 288/373 (77.2%) residents experiencing a fall, 429/659 (65.1%) presenting with delirium and 180/2765 (6.5%) with urinary incontinence were on one or more interacting drugs. In the IBenC project, 78/172 (45.3%) participants experiencing a fall, 80/182 (44.0%) presenting with delirium and 36/504 (7.1%) with urinary incontinence were on one or more interacting drugs.Conclusion: Drug-geriatric syndromes interactions are common in long-term care patients. Future studies and interventions aimed at improving pharmacological prescription in the long-term care setting should assess not only drug-drug and drug-disease interactions, but also interactions involving geriatric syndromes. [ABSTRACT FROM AUTHOR]
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- 2018
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85. Quality of care in European home care programs using the second generation interRAI Home Care Quality Indicators (HCQIs)
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Foebel, Andrea D., primary, van Hout, Hein P., additional, van der Roest, Henriëtte G., additional, Topinkova, Eva, additional, Garms-Homolova, Vjenka, additional, Frijters, Dinnus, additional, Finne-Soveri, Harriet, additional, Jónsson, Pálmi V., additional, Hirdes, John P., additional, Bernabei, Roberto, additional, and Onder, Graziano, additional
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- 2015
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86. Depressive and anxiety disorders and risk of subclinical atherosclerosis Findings from the Netherlands Study of Depression and Anxiety (NESDA)
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Seldenrijk, Adrie, Vogelzangs, Nicole, van Hout, Hein P. J., van Marwijk, Harm W. J., Diamant, Michaela, and Penninx, Brenda W. J. H.
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LIFETIME HISTORY ,PSYCHOMETRIC PROPERTIES ,SYMPTOMS ,ANKLE-BRACHIAL INDEX ,Depression ,CAROTID ATHEROSCLEROSIS ,CORONARY-ARTERY-DISEASE ,WOMEN ,Subclinical atherosclerosis ,HEART-DISEASE ,MAJOR DEPRESSION ,Anxiety ,INTIMA-MEDIA THICKNESS - Abstract
Objective: Current evidence regarding the association between psychopathology and subclinical atherosclerosis show inconsistent results. The present study examined whether subclinical atherosclerosis was more prevalent in a large cohort of persons with depressive or anxiety disorders as compared to non-depressed and non-anxious controls. Methods: Baseline data from the Netherlands Study of Depression and Anxiety were used, including 2717 persons, free of clinical cardiovascular disease. Participants had a DSM-IV-based current or remitted depressive (major depressive disorder, dysthymia) or anxiety (social phobia, generalized anxiety disorder, panic disorder, agoraphobia) disorder (n=2115) or were healthy controls (n=602). Additional clinical characteristics (severity, duration, age of onset and medication) were assessed. Ankle-brachial index (ABI) was used as a measure of vascular risk and was categorized as low (1.40), which was previously designated as a cardiovascular risk factor, reflecting arterial stiffness and wall calcification. Results: As compared to normal controls, persons with current (i.e., past year) depressive, anxiety or comorbid depressive and anxiety disorders showed a two- to threefold increased odds of low ABI (OR=2.78, 95% CI=1.05-7.35; OR=3.14, 95% CI=1.25-7.85; OR=2.67, 95% CI=1.09-6.51, respectively). No associations were found with mildly low or high ABI. Also, we did not further find a differential role for symptoms severity, duration, age of onset, and use of psychotropic medication in the link between psychopathology and subclinical atherosclerosis. Conclusion: Persons with current depressive or anxiety disorders were more likely to have subclinical atherosclerosis compared to healthy controls. (C) 2010 Elsevier Inc. All rights reserved.
- Published
- 2010
87. Dutch family physicians’ awareness of cognitive impairment among the elderly
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van den Dungen, Pim, primary, Moll van Charante, Eric P., additional, van de Ven, Peter M., additional, Foppes, Gerbrand, additional, van Campen, Jos P. C. M., additional, van Marwijk, Harm W. J., additional, van der Horst, Henriëtte E., additional, and van Hout, Hein P. J., additional
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- 2015
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88. Depression increases the onset of cardiovascular disease over and above other determinants in older primary care patients, a cohort study
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van Marwijk, Harm W. J., primary, van der Kooy, Koen G., additional, Stehouwer, Coen D. A., additional, Beekman, Aartjan T. F., additional, and van Hout, Hein P. J., additional
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- 2015
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89. Screening for Mild Cognitive Impairment and Dementia with Automated, Anonymous Online and Telephone Cognitive Self-Tests.
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Van Mierlo, Lisa D., Wouters, Hans, Sikkes, Sietske A. M., Van der Flier, Wiesje M., Prins, Niels D., Bremer, Jonne A. E., Koene, Teddy, and Van Hout, Hein P. J.
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MILD cognitive impairment ,DIAGNOSIS of dementia ,COGNITIVE testing ,DISEASE diagnosis in older people ,NEUROPSYCHOLOGICAL tests ,PATIENT self-monitoring ,DIAGNOSIS ,DEMENTIA ,NEUROLOGIC examination ,ONLINE information services ,SELF-evaluation ,TELEPHONES ,RECEIVER operating characteristic curves - Abstract
Background: Many older people worry about cognitive decline. Early cognitive screening in an anonymous and easily accessible manner may reassure older people who are unnecessarily worried about normal cognitive aging while it may also expedite help seeking in case of suspicious cognitive decline.Objective: To develop and validate online and telephone-based automated self-tests of cognitive function.Methods: We examined the feasibility and validity of the self-tests in a prospective study of 117 participants of whom 34 had subjective cognitive decline (SCD), 30 had mild cognitive impairment (MCI), and 53 had dementia. The ability of these self-tests to accurately distinguish MCI and dementia from SCD was examined with ROC curves. Convergent validity was examined by calculating rank correlations between the self-tests and neuropsychological tests.Results: Both the online and telephone cognitive self-tests were feasible, because the majority of participants (86% and 80%, respectively) were able to complete them. The online self-test had adequate diagnostic accuracy in the screening for MCI and dementia versus SCD with an Area under the Curve (AUC) of 0.86 (95% CI: 0.78-0.93). The AUC of the MMSE was 0.82 (95% CI: 0.74-0.89). By contrast, the telephone self-test had lower diagnostic accuracy (AUC = 0.75, 95% CI: 0.64-0.86). Both self-tests had good convergent validity as demonstrated by moderate to strong rank correlations with neuropsychological tests.Conclusion: We demonstrated good diagnostic accuracy and convergent validity for the online self-test of cognitive function. It is therefore a promising tool in the screening for MCI and dementia. [ABSTRACT FROM AUTHOR]- Published
- 2017
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90. Implementing the chronic care model for frail older adults in the Netherlands: study protocol of ACT (frail older adults: care in transition)
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Muntinga, Maaike E, Hoogendijk, Emiel O, van Leeuwen, Karen M, van Hout, Hein P J, Twisk, Jos W R, van der Horst, Henriette E, Nijpels, Giel, Jansen, Aaltje P D, Muntinga, Maaike E, Hoogendijk, Emiel O, van Leeuwen, Karen M, van Hout, Hein P J, Twisk, Jos W R, van der Horst, Henriette E, Nijpels, Giel, and Jansen, Aaltje P D
- Abstract
BACKGROUND: Care for older adults is facing a number of challenges: health problems are not consistently identified at a timely stage, older adults report a lack of autonomy in their care process, and care systems are often confronted with the need for better coordination between health care professionals. We aim to address these challenges by introducing the geriatric care model, based on the chronic care model, and to evaluate its effects on the quality of life of community-dwelling frail older adults.METHODS/DESIGN: In a 2-year stepped-wedge cluster randomised clinical trial with 6-monthly measurements, the chronic care model will be compared with usual care. The trial will be carried out among 35 primary care practices in two regions in the Netherlands. Per region, practices will be randomly allocated to four allocation arms designating the starting point of the intervention.PARTICIPANTS: 1200 community-dwelling older adults aged 65 or over and their primary informal caregivers. Primary care physicians will identify frail individuals based on a composite definition of frailty and a polypharmacy criterion. Final inclusion criterion: scoring 3 or more on a disability case-finding tool.INTERVENTION: Every 6 months patients will receive a geriatric in-home assessment by a practice nurse, followed by a tailored care plan. Expert teams will manage and train practice nurses. Patients with complex care needs will be reviewed in interdisciplinary consultations.EVALUATION: We will perform an effect evaluation, an economic evaluation, and a process evaluation. Primary outcome is quality of life as measured with the Short Form-12 questionnaire. Effect analyses will be based on the "intention-to-treat" principle, using multilevel regression analysis. Cost measurements will be administered continually during the study period. A cost-effectiveness analysis and cost-utility analysis will be conducted comparing mean total costs to functional status
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- 2012
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91. Substantial between-country differences in organising community care for older people in Europe--a review.
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Van Eenoo, Liza, Declercq, Anja, Onder, Graziano, Finne-Soveri, Harriet, Garms-Homolová, Vjenka, Jónsson, Pálmi V., Dix, Olivia H. M., Smit, Johannes H., van Hout, Hein P. J., and van der Roest, Henriëtte G.
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COMMUNITY health services ,AGE distribution ,AGING ,HEALTH care rationing ,HEALTH services accessibility ,HEALTH status indicators ,MEDICAL care ,PATIENTS ,POPULATION ,PUBLIC health ,HUMAN services programs - Abstract
Background: The European population is aging. The main drivers of public spending on health care for people of 65 years and older are hospital admission and admission to long-term care facilities. High quality community care can be a cost-effective and quality solution to respond to the impact of ageing populations on health-care systems. It is unclear how well countries are equipped to provide affordable and quality community care. The aim of this article is to describe and compare community care delivery with care-dependent older people in Europe. Methods: This study is conducted within the European Union-financed IBenC project [Identifying best practices for care-dependent elderly by Benchmarking Costs and outcomes of community care (FP7)] in which six European countries are involved. To compare the community care delivery with care-dependent older people in these countries, we performed a systematic comparison of macro indicators using metadata complemented with data from multinational surveys. Results: Data on the following dimensions are described and compared: population of the country, governmental expenditures on health, sources of community health services funding, governmental vision and regulation on community care, community care organisations and care professionals, eligibility criteria for and equity in receiving care and the involvement of informal care. Conclusion: Because of the variations in the European community care contexts, the growing demand for community care as a cost-effective and quality solution to the care burden of aging populations will have country-specific impacts. When learning from other countries' best practices, in addition to researchers, policy makers should take full account of local and national care contexts. [ABSTRACT FROM AUTHOR]
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- 2016
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92. The identification of frail older adults in primary care: comparing the accuracy of five simple instruments
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Hoogendijk, Emiel O., primary, van der Horst, Henriëtte E., additional, Deeg, Dorly J. H., additional, Frijters, Dinnus H. M., additional, Prins, Bernard A. H., additional, Jansen, Aaltje P. D., additional, Nijpels, Giel, additional, and van Hout, Hein P. J., additional
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- 2012
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93. Effectiveness of Family Meetings for Family Caregivers on Delaying Time to Nursing Home Placement of Dementia Patients: A Randomized Trial
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Joling, Karlijn J., primary, van Marwijk, Harm W. J., additional, van der Horst, Henriëtte E., additional, Scheltens, Philip, additional, van de Ven, Peter M., additional, Appels, Bregje A., additional, and van Hout, Hein P. J., additional
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- 2012
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94. Is It Time for a Change? A Cost-Effectiveness Analysis Comparing a Multidisciplinary Integrated Care Model for Residential Homes to Usual Care
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MacNeil Vroomen, Janet L., primary, Boorsma, Marijke, additional, Bosmans, Judith E., additional, Frijters, Dinnus H. M., additional, Nijpels, Giel, additional, and van Hout, Hein P. J., additional
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- 2012
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95. Does a Family Meetings Intervention Prevent Depression and Anxiety in Family Caregivers of Dementia Patients? A Randomized Trial
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Joling, Karlijn J., primary, van Marwijk, Harm W. J., additional, Smit, Filip, additional, van der Horst, Henriëtte E., additional, Scheltens, Philip, additional, van de Ven, Peter M., additional, Mittelman, Mary S., additional, and van Hout, Hein P. J., additional
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- 2012
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96. Identifying target groups for the prevention of depression among caregivers of dementia patients
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Joling, Karlijn J., primary, Smit, Filip, additional, van Marwijk, Harm W. J., additional, van der Horst, Henriëtte E., additional, Scheltens, Philip, additional, Schulz, Richard, additional, and van Hout, Hein P. J., additional
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- 2011
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97. The accuracy of family physicians' dementia diagnoses at different stages of dementia: a systematic review
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van den Dungen, Pim, primary, van Marwijk, Harm W. M., additional, van der Horst, Henriëtte E., additional, Moll van Charante, Eric P., additional, MacNeil Vroomen, Janet, additional, van de Ven, Peter M., additional, and van Hout, Hein P. J., additional
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- 2011
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98. High incidence of clinically relevant depressive symptoms in vulnerable persons of 75 years or older living in the community
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Dozeman, Els, primary, van Marwijk, Harm W.J., additional, van Schaik, Digna J.F., additional, Stek, Max L., additional, van der Horst, Henriette E., additional, Beekman, Aartjan T.F., additional, and van Hout, Hein P., additional
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- 2010
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99. What do community-dwelling people with dementia need? A survey of those who are known to care and welfare services
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van der Roest, Henriëtte G., primary, Meiland, Franka J. M., additional, Comijs, Hannie C., additional, Derksen, Els, additional, Jansen, Aaltje P. D., additional, van Hout, Hein P. J., additional, Jonker, Cees, additional, and Dröes, Rose-Marie, additional
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- 2009
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100. Stepped-Care Prevention of Anxiety and Depression in Late Life
- Author
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van't Veer-Tazelaar, Petronella J., primary, van Marwijk, Harm W. J., additional, van Oppen, Patricia, additional, van Hout, Hein P. J., additional, van der Horst, Henriëtte E., additional, Cuijpers, Pim, additional, Smit, Filip, additional, and Beekman, Aartjan T. F., additional
- Published
- 2009
- Full Text
- View/download PDF
Catalog
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