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Studying the prospects of the colour phenomenon for the formation of the livable environment necessitates consideration of the integrity of the space of colour effect, including the biological colour behavior; intended Ra-therapy / chromotherapy; permanent polychromy of the environment constantly influencing the human organism; involvement of chromaticity in the ideas of livability of the environment and a healthy lifestyle; as well as the necessity of permanent monitoring in the constantly changing conditions of the reality.

The optimum frequency-manipulated signal for an estimation of security of channels of information leakage in the digital form is investigated. The system of signals used for an information transfer as set of signals, united by a uniform rule of construction is considered. The optimum system of signals providing the maximum noise stability at the minimum relations of energy of bit to spectral density of capacity of noise in channels of information leakage, methods of an estimation of security of discrete systems of signals in information leakage channels are offered at influence of noise of high level of type white noise, and also a choice and a substantiation of an optimum signal which will allow to estimate security of channels of information leakage.

Evaluation method of security assessment a speech signal in information leakage channel under high-level noise with significant Bandpass flatness by complex measuring signal with a large base in equal intelligibility bands is proposed. Using the mathematical approach a derivative of cross-correlation function between complex measuring signal with a large base at the inlet and outlet channel speech information leakage allows to determine the position of the axis points in which derivative is zero. After that its time delay and frequency shift at the output of leakage channel of speech information within а minimum mean square error are determined. Compensation with time delay high accuracy and frequency shift complex measuring signal with a large base at the output of information leakage channel allowed to significantly improving the accuracy and sensitivity of the assessment of protection a speech signal in information leakage channel.

This paper proposes to make an assessment of speech signal protection in information leakage channel by frequency-time processing of complex measurement signal with a large base within a band equal intelligibility using Hilbert transform to represent it in an analytical form and preliminary reduction of the detection threshold n-multiples sequential synchronous accumulation of spectral components using direct and inverse fast Fourier transform. High accuracy and sensitivity assessment of the parameters of a complex measurement signal with a large base in information leakage channel on background high level of noise achieved by compensating with a minimum mean square error its time delay and frequency offset.

Purpose of the study — to justify the algorithm for evaluation of bipolar defects in anterior shoulder instrability using the most accurate, statistically significant and reproducible methods which would make the algorithm applicable in practical surgery.Materials and methods. The authors established 4 groups with 6 patients in each with shoulder instability, group distribution was based on glenoid defect size: small (25%). All 24 patients underwent 3D-CT, 3D VIBE MRI and shoulder arthroscopy. Measurements were taken by 7 specialists 5 of whom measured defect during arthroscopy. Glenoid defect was measured by linear and sectional relation methods. Pico method on 3D-CT was taken as the “golden standard”. Accuracy was verified by analysis of variance with post-hoc comparison. Reproducibility was evaluated by intraclass correlation coefficient.Results. All groups excluding the one with massive glenoid defects demonstrated significant differences from the model (p≤0,05) for measurements during arthroscopy and examinations by 3D-CT and 3D VIBE MRI. Restrospective analysis confirmed the least accuracy and the worst reproducibility of visual evaluation of glenoid defects less than 25%. Sectional relation method on 3D-CT had the maximum accuracy and reproducibility in all groups (PE = 1,29%±2,39%, ICC = 0,756-0,856), excluding the group with massive defects, where researched measurement methods had close accuracy when applied on 3D-CT, 3D VIBE MRI and during arthroscopy. Linear relation method on 3D-CT overestimated the defect volume at 2,1-7,9% and demonstrated less reliable reproducibility (PE = 3,22%±5,31%, ICC = 0,612-0,621). The highest error (up to 7,9%) was demonstrated by linear method in case of borderline defects in the III group of 20-25%. Insufficient conformity of results for linear (ICC = 0,42) method and moderate conformity for sectional (ICC = 0,62) method were observed during comparison of 3D VIBE MRI with 3D-CT. MRI underestimated the value of small defects and overestimated large defects. Reproducibility of measurements on 3D-CT by different operators was moderate for visual (ICC=0,594) and linear methods (ICC = 0,621) and good for sectional method (ICC = 0,756). Reproducibility of measurements by each operator also was moderate for visual and linear methods (ICC = 0,553 и ICC = 0,612) and good for sectional method (ICC = 0,856). The authors suggested an algorithm for selection of examination method and measurements for defects of articular surfaces which also considers the main factors of prognosis and risk of recurrent instability.Conclusion. Sectional relation method on 3D-CT is the most precise and reproducible method of glenoid defect measurements used in the clinical practice. MRI use without CT is inadmissible for bipolar defects of borderline size. Suggested algorithm allows not to make CT examination at extreme ISIS values and increases the share of osteoplastic surgeries due to identification of off-track injuries with glenoid defects of borderline size (15-25%).

The nearshore hydrodynamic fields are produced by the nonlinear interactions of the shoaling waves of different time scales and currents. To simulate the wind wave propagated to the coasts, wave generated nearshore currents, nonlinear-dispersive wave transformation and wave diffraction in interaction with coastal and port structure, sediment transport and coastal erosion, the chains of the models should be used. The objective of the paper is to provide an overview of the results of the application of the model chains for the assessment of the wave impacts on new port designed at the Ob lip, Kara Sea to demonstrate needs for further development of the nonlinear models for the coastal engineering applications. The open source models WaveWatch III and SWAN has been used to simulate wave statistics of the dedicated areas of the studied coastal areas in high resolution to calculate the statistical parameters of the extreme wave approaching coastal zone construction in accordance with coastal engineering standards.

Climate change strongly impacts regions in high latitudes and altitudes that store high amounts of carbon in yet frozen ground. Here the authors show that the consequence of these changes is global warming of permafrost at depths greater than 10 m in the Northern Hemisphere, in mountains, and in Antarctica.

Image and branding are modern trends and a topical discourse, a simulation space, a virtual world and the facts of life of civilization, an eternal reflection of authenticity and universality of the promoted product. They influence the achievement of positive reputation of states, regions/territories, cities, corporations/firms, entities, goods and their investment attractiveness. Working with a real space, milieu and culture of the territory allows for revealing the most typical features of the image of the territory and demonstrates both individual, personalized interpretations of the image and the most popular (often already branding) images of the ‘place’.

This study is an attempt to suggest a new state system of permafrost monitoring, primarily for energetic infrastructure, based on past approaches and achievements in Russia for over a hundred years of Arctic studies. The methodology of this study is based on general theoretical methods of scientific research. Historical (retrospective analysis of the development of the monitoring system of long-term permafrost in Russia) and logical (inductive generalization) methods were applied. The structure and methods of permafrost monitoring in the Soviet Union and new technologies used nowadays to establish permafrost monitoring systems, taking into account modern Arctic energetic development, have been analyzed.

Background: The aim of this study was to evaluate patency following the deployment of a bare-metal stent (BMS) or covered stent (CS) across a traumatic occlusive peripheral arterial lesion and to estimate the feasibility of urgent stent placement for temporary endovascular shunting. Methods: Fifteen sheep (25–45 kg) underwent laparoscopic creation of a left external iliac artery (EIA) thrombosis by means of repeated clamping. Sixty minutes after achievement of thrombotic occlusion, animals were randomized into one of three groups: no-treatment (control group), a BMS group, or CS group. Animals were followed up for 30 days with no anticoagulants or anti-platelet drugs administered postoperatively. Doppler ultrasound, computed tomography angiography (CTA), and digital subtraction angiography (DSA) were used to evaluate EIA patency. Results: Stent implantation resulted in the restoration of in-line flow through the EIA in all cases. The peak systolic velocity (PSV) in the injured limb increased from 10 (0–16) to 31 (28–37) cm/s in the BMS group (p < 0.0001) and from 15 (7–18) to 24 (21–29) cm/s in the CS group (p = 0.043) immediately after stent deployment (both p = 0.001 compared with the control group). There was no difference in the PSV between the groups at post-injury day 3, and thereafter. Day-14 CTA and day-30 DSA demonstrated only one patent stent in each study group. Conclusions: Urgent stent (BMS or CS) implantation can restore arterial patency of a traumatic occlusion for a short period of time and serve as a temporary endovascular shunt. Distal embolization can complicate this procedure and worsen long-term patency.

Celebrations as a space integrating traditions and peculiarities of contemporary culture and immerging authentic images and customs in today’s realities is an important part of the existence of a “space”, a territory and a city. The ability of unique and autochronous peculiarities of celebrations to be integrated with universal standards makes it possible to use celebrations as an image system promoting the territory and its identity.

The subject of the paper is the response of the natural environment to various impacts associated with the oil and gas industry. The paper is devoted to the analysis of the current state of implementation of the project of development of the gas transportation system "Power of Siberia" in East and Southeast Siberia. The purpose of the study is to show the problems that arise at various stages of creating the object. That includes choosing the apropriate pipeline route and method of pipe laying. The project of gas transoptation system (GTS) "Power of Siberia" in East Siberia is being successfully implemented recently. The stages of exploration and design are completed, pipe is being layed. After successful research and design, one of the most important stages (pipe laying and system building in general) has started. Studying the seasonal and permafrost rocks is a very special direction in the general integrated system of engineering and geological knowledge. It is important to consider both studied parameters such as composition, structure, properties of rocks, and features of aggregate states of the object of research. Negative temperatures cause fundamental differences in the composition of rocks with the development of diverse underground ice, sometimes constituting up to 90% of the thickness, and other characteristics. The main results of ecological and geocryological research recently performed by Melnikov Permafrost Institute of the Siberian Branch of the Russian Academy of Sciences, which have revealed the main difficulties of the project and show the ways of their solution, are given. Advantages and features of the selected route in the specific engineering and geological conditions are described. The need for underground method of pipe laying is confirmed. It is concluded that complex and diverse natural conditions of the route of the GTS determine a number of specific problems at the stages of construction and operation within areas with permafrost soils and dangerous geocryological and engineering-geocryological processes. It is possible to avoid them only while studying the most difficult areas. Recommendations on the structure of department of engineering and geocryological monitoring are given.

The article related to the electromagnetic compatibility and radio ecologic. Microwave auditory effect was analyzed, as the observed phenomenon of high-frequency radio signals transformation into acoustic oscillations. This phenomenon was called a radio sound effect. The physical interaction mechanisms of amplitude-modulated high-frequency electrical signal with a perfect non-conductor were considered, leading to the spectating transformation in the low frequency mechanical vibrations or acoustic harmonics of the modulated signal. In the paper presented studies of the possible effects of direct exposure to high-frequency field, for example, in physical therapy, or medical practice.

The article studies the forms of interaction, gaps and intercrossing between the paradigms of East and West. Interpretation of the dichotomy as a model and value of culture and as a significant component of the worldview is presented in the article as a process of combination of cultural norms within the Whole. The idea of ‘transmutation contact’ is proposed for the discussion of peculiarities of the notion East-West. The mobility of borders and the ambiguity of the notion East-West predetermine different discourses of the discussion in the spaces of rational-irrational, tradition-nontradition, enlightenment and barbarism. It can be explained by the fact that the East-West dichotomy is integrated in the universe, the microspace and macrospace.

Purpose: influence of students’ targeted and regular physical activity on their life quality. Material: in the research students (n=325, age 18-21 years) participated. Students’ life quality was studied with the help of questionnaire "MOS SF-36» (J.E.Ware). We determined students’ physical workability and physical fitness. Results: formation of students’ physical activity was based on the worked out technology: 1) motor functioning for general endurance; 2) accent on speed-power training was made in second half of semester; 3) training of dexterity and flexibility was realized considering certain kind of academic material and future professional activity; 4) the structure of trainings in academic year included 3 stages. At first stage (September, October) 70% of time was spent for endurance, 15% - for quickness and 15% for strength. At second stage (November, March) 50% was assigned for endurance, 30% - for quickness and 20% - for strength. At third stage (April, May) 40% of time was assigned for quickness, 40% - for strength and 30% - for endurance. As a result of realization of the worked out technology for students’ physical activity their individual health improved and became the factor of students’ life quality perfection. Conclusions: targeted and regular physical activity of students confidently influences on their individual health by all indicators: organism’s functional reserves; physical workability and fitness, way of life and organism’s resistance. Targeted and regular physical activity of students facilitates improvement of students’ life quality.

The article devotes to investigations the caves Heetey - natural monument Trans-Baikal Territory, in connection with the problem of their preservation during the blasting development of the nearby located Ust'-Borzinsky limestone deposits. Limestone processing is planned to open by a career with 5 ledges height of 15 m each. The characteristics of natural conditions, geological, and hydrogeological properties of permafrost enclosing rock massif, provides information about the shape, location and characteristics of ice cover, which affects on the dynamic stability of the cave and its elements. The analysis of the results of experimental studies of dynamic stability of karst cave Heetey to the effects of explosions in the development of the open method of Ust'-Borzinsky limestone deposits is presented. The main purpose of engineering and seismic measurements of vibrations of the rock mass enclosing Heetey cave was to study the amplitude and frequency content of vibrations to assess the seismic effect of explosions carried out in the near quarry with limestone mining. Actual measurements of the parameters of the rocks fluctuations in the cave Heetey included varying the total weight of the impact of charges, the distance from the source of vibrations to the registration points, the difference in the parameters of group explosions on the amplitude-frequency characteristics of wave propagation in a cave in the enclosing rock mass. The analysis of the results of field measurements of cave rock vibrations and calculations, of their dynamic stability taking into account the effect of the array of bottom cover of ice, filling with water of the cave and shielding devices is cited. Particular attention is paid to the effect of empty and filled with ice holes in the rock mass in the propagation of mechanical vibrations in it. Presented findings of scientific and applied pattern.

The use of provincial design as a special form of manifestation of peculiarity of the “place” is determined by its relevancy for today’s world culture and common development tendencies of the Siberian region. The Provincial Design Project worked out by the Department of Design of Irkutsk National Research Technical University reflects the peculiarities of the art and design space of the region, corresponds to the current context and challenges of the profession and may serve as specific means of the territorial image formation.

The article discusses some of the characteristics of Transcarpathian region soils current conditions. For evaluation of the efficiency of agricultural land we propose a nonlinear mathematical model of soil fertility depending on the economic costs on growing crops. Efficiency of agricultural land use in Transcarpathian region of Ukraine in three landscape zones by traditional for them agricultural crops is assessed.

The methods of space spectrophotometry were used to identify soil types, to determine soil granulometric composition and to evaluate quantitative indicator of humus content in the soil based on mathematical calculations using spectral channels data of space images and terrestrial research data for different landscape zones of Transcarpathian region. After statistical processing of data we classified the types of soil, identified quadratic dependence between the spectral brightness of images and the content of physical clay in the soil and obtained quantitative indicators of humus content in the soil using the red channel data.

Parameters of waves in water area of the projected port are normally obtained using physical and numerical modelling. Physical modelling allows defininig structural details of the port’s facilities and provides with information for the appropriate selection of a numerical model. The problems created by this approach are shown in the case study of the projected port in Vostok (East) Bay, the Sea of Japan. The experimental study of waves propagation in the port water area was carried out in the wave basin. The port area was reproduced at a scale of 1:50, and the modelling was conducted under the Froude number similarity. Experimental results are provided for the study of wave propagation in the port model from the effects of the waves of 5 % exceedance probability. To confirm the results of the laboratory experiments, four relevant mathematical models were used, one of them is the ARTEMIS model which is based on gentle slopes equations. The heights of numerically modeled waves in the control points were compared with the waves measured with sensors-wave gauges. The calculated values at the control point and minimum and maximum values in a circular neighborhood with the radius of 30 m (1/4 of the average wavelength of 120 m) were compared with the results of the experiments. The proposed approach allows comparing the results of physical modelling with the results of numerical modelling and selecting the appropriate numerical model based on the results of the comparison.

High-affinity IL-2Rα expressed by Tregs mitigates the potential of IL-2 use in cancer therapy. Here, the authors fuse IL-2 with an NKDG2 binding domain, and show that it induces IL-2 signalling selectively in NKG2D+cells, delaying tumour growth in mice without the side effects of conventional IL-2 therapy.

Aim. To study molecular effects of tiotriazoline in 30 patients with stable angina I-III functional class.Material and methods. Comparison of molecular effects of cardioprotection is done based on dynamics of exercise tolerance dynamics, and via proteomic methods of investigation, questionnaires assessment of life quality in patients with ischemic heart disease (IHD).Results. It was found, that tiotriazoline improves exercise tolerance, shows strong cardioprotective effect that includes antioxidant and cytoprotection effects in IHD patients.Conclusion. Tiotriazoline helps to reduce the mean number of angina attacks in IHD patients, as to improve mean functional class.

The authors determined the efficacy of main methods of MR-imaging and their part in differentiated diagnostics of focal liver lesions. There were examined 256 patients and 414 liver lesions were analyzed. It was shown that the efficacy of conventional research without application of contrast medium was very limited (efficacy of mathematical model 58%). The data obtained during dynamic contrast enchancement (efficacy of the model 67%) were the basis for differentiated diagnostics for majority of nosological forms. The investigation using hepatotropic contrast medium had the greatest possibilities (efficacy of the model 80%). MR-diffusion is the effective procedure for visualization of focal liver lesions, but its possibilities in differentiated diagnostics is limited.