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Pre-obesity, as a significant risk factor for the progression of metabolic syndrome (MS), has become a prevalent public health threat globally. In this three-year longitudinal study of pre-obese women at baseline, the goal was to clarify the female-specific bidirectional relationship between the risk of MS and blood alanine aminotransferase. In this manuscript, the MS score was determined using the following equation: MS score = 2*waist/height + fasting glucose/5.6 + TG/1.7 + SBP/130-HDL/1.02 for men and 1.28 for women, which is highly related to the risk of MS. With 2,338 participants, a hierarchical nonlinear model with random effects was utilized to analyze the temporal trends of serum characteristics from 2017 to 2019. A bivariate cross-lagged panel model (CLPM) was employed to estimate the structural relations of frequently measured variables at three different time points to determine the directionality of the relationship between the risk of MS and serum characteristics. MassARRAY Analyzer 4 platforms were used to evaluate and genotype candidate SNPs. In this study, the MS score only rose with age in females; it was positively correlated with serum alanine aminotransferase (ALT) in females; the CLPM revealed that the MS score in 2017 predicted ALT in 2018 (β = 0.066, p  < 0.001); and ALT in 2018 predicted an MS score in 2019 (β = 0.037, p  < 0.050); both relationships were seen in females. Additionally, the MS score in elderly females with NAFLD was related to the rs295 in the lipoprotein lipase ( LPL ) gene ( p  = 0.042). Our work showed that there may be female-specific causal correlations between elevated ALT and risk of MS and that the polymorphism rs295 in LPL may serve as a marker for the prognosis of MS. The genetic roles of rs295 in the LPL gene in the onset of MS and the development of ALT in the elderly Chinese Han population are thus provided by this, offering one potential mechanism., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (© 2023 Wu, Feng, Zhao, Tang, Xiong, Shi, Li, Song, You, Wang, Zhang, Ji and Liu.)

The self-assembly of organic TCNQF˙⁻ radicals (2-fluoro-7,7,8,8-tetracyano-p-quinodimethane) and the anisotropic [Tb(valpn)Cu](3+) dinuclear cations produced a single-chain magnet (SCM) involving stacking interactions of TCNQF˙⁻ radicals (H2valpn is the Schiff base from the condensation of o-vanillin with 1,3-diaminopropane). Static and dynamic magnetic characterizations reveal that the effective energy barrier for the reversal of the magnetization in this hetero-tri-spin SCM is significantly larger than the barrier of the isolated single-molecule magnet based on the {TbCu} dinuclear core., (© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Treatment of [Mn(dpop)(H2O)2]Cl2 (dpop = 2,13-dimethyl-3,6,9,12,18-pentaazabicyclo-[12.3.1]octadeca-1(18),2,12,14,16-pentaene) with K4[Mo(CN)7]·2H2O under varied synthetic conditions afforded four different compounds: {[Mn(dpop)]4[(dpop)Mn(H2O)]2[Mo(III)(CN)7]3·27H2O}n (1), {[(dpop)Mn(H2O)][Mo(III)(CN)7][Mn(dpop)]3[Mo(IV)(CN)8]·29H2O}n (2), {[(dpop)Mn(H2O)]2[Mo(IV)(CN)8]2[Mn(dpop)]4[Mo(III)(CN)7]·12H2O}n (3), and [(dpop)Mn(H2O)]2[Mo(IV)(CN)8]·9H2O (4). Compound 1 contains only [Mo(III)(CN)7](4-) anions and exhibits a corrugated two-dimensional layered architecture. The structure of 2 with a 1 : 1 ratio of Mo(III) : Mo(IV) is best described as a ladder-like chain composed of [Mo(III)(CN)7](4-)-based pentanuclear [Mo(III)Mn(II)4] fragments which are further linked by in situ produced [Mo(IV)(CN)8](4-) anions. In the case of 3, [Mn8Mo8] rings containing bent [Mo(III)Mn(II)2] fragments are extended into a two-dimensional layer with the ratio of [Mo(CN)7](4-) : [Mo(CN)8](4-) being 1 : 2. Compound 4 exhibits a bent trinuclear structure in which two CN(-) groups of [Mo(CN)8](4-) function as μ2-bridges to [Mn(dpop)(H2O)](2+) fragments. Magnetic studies suggest significant antiferromagnetic coupling interactions occur between Mo(III) and Mn(II) ions while, not surprisingly, interactions between the Mn(ii) ions through diamagnetic [Mo(IV)(CN)8](4-) anions are negligible. Compound 1 exhibits ferrimagnetic ordering below 3.0 K whereas 2 shows the signature of single molecule magnet behavior with slow relaxation of the magnetization and an effective energy barrier (U(eff)) of 8.1 K.

The 3-D coordination polymer with the basic formula Cd2(TCNQ)3.5(H2O)2 is the first instance of the coexistence of the bridging modes μ2, μ3 and μ4 for TCNQ in one network. Single crystal measurements revealed the compound to be a good semiconductor with a room temperature conductivity of 5.8 × 10(-3) S cm(-1).

The π-π stacking interactions between tptz units from adjacent Sm(tptz)(HCOO)(3) coordination nanotubes leads to additional 1D channels (tptz = 2,4,6-tris(2-pyridyl)-s-triazine). The present compound is a rare case of a tubular porous material with both hydrophobic and hydrophilic channels. Permanent porosity was confirmed by N(2) adsorption isotherms.

Reactions between trivalent rare earth ions (M(III) = La, Pr, Nd, Sm, Eu, Gd, Dy, Ho, Er and Yb) and the radical anion of 2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodimethane (TCNQF(4)) produce a family of mononuclear complexes {M[(TCNQF(4))](2)[H(2)O](x)}.(TCNQF(4))(3H(2)O), x = 6, 7. The cationic complex {M(III)([TCNQF(4)](-) )(2)[H(2)O](x)}(+) cocrystallizes with one [TCNQF(4)](-) radical anion and three water molecules. One of the coordinated [TCNQF(4)](-) radicals is involved in pi-pi stacking interactions with the uncoordinated [TCNQF(4)](-) radicals which leads to the antiferromagnetic coupling for these ((TCNQF(4))(2))(2-)pi-dimers. The second coordinated [TCNQF(4)](-) remains as a radical ligand and is not involved in pi-pi interactions. Magnetic studies indicate that the Sm compound magnetically orders at 4.4 K and that a fraction of the Gd and Dy samples undergo magnetic ordering at 3.7 K and 4.3 K respectively due to partial dehydration (loss of interstitial water molecules). Diamagnetic metal ions were used to generate magnetically dilute Gd, and Dy compounds that do not exhibit any signs of magnetic ordering.

A series of isostructural compounds with formula [M(TCNQF(4))(2)(H(2)O)(6)]TCNQF(4)3 H(2)O (M=Tb (1), Y (2), Y:Tb (74:26) (3), and Y:Tb (97:3) (4); TCNQF(4)= tetrafluorotetracyanoquinodimethane) were prepared and their magnetic properties investigated. Compounds 1, 3, and 4 show the beginning of a frequency-dependent out-of-phase ac signal, and decreasing intensity of the signal with decreased concentration of Tb(III) ions in the diluted samples is observed. No out-of-phase signal was observed for 2, an indication that the behavior of 1, 3, and 4 is indicative of slow paramagnetic relaxation of Tb(III) ions in the samples. A more detailed micro-SQUID study at low temperature revealed an interplay between single-molecule magnetic (SMM) behavior and a phonon bottleneck (PB) effect, and that these properties depend on the concentration of diamagnetic yttrium ions. A combination of SMM and PB phenomena was found for 1, whereby the PB effect increases with increasing dilution until eventually a pure PB effect is observed for 2. The PB behavior is interpreted as being due to the presence of a "sea of organic S=1/2 radicals" from the TCNQF(4) radicals in these compounds. The present data underscore the fact that the presence of an out-of-phase ac signal may not, in fact, be caused by SMM behavior, particularly when magnetic metal ions are combined with organic radical ligands such as those found in the organocyanide family.

Four ion-pair complexes of [Ni(dmit)(2)](-) with [NO(2)bzql](+) have been obtained, which belong to two kinds of polymorph forms, [NO(2)bzql][Ni(dmit)(2)] (1alpha and 1beta) and [NO(2)bzql][Ni(dmit)(2)].CH(3)COCH(3) (2alpha and 2beta) (where dmit = 2-thioxo-1,3-dithiole-4,5-dithiolate and [NO(2)bzql](+) = 1-(4-nitrobenzyl)quinolinium). Though 1alpha, 2alpha, and 2beta all show anionic dimerization structures at room temperature, they have different anionic and cationic arrangement fashions, which give rise to different magnetic behaviors for these polymorphs or pseudo-polymorphs. Compounds 1alpha, 1beta, and 2alpha exhibit magnetic bistabilities. In particular, 1alpha has a hysteretic loop at approximately 55 K, while 2beta does not display a spin transition in the 2-300 K range. On the basis of the crystal structure data of 2alpha in high- and low-temperature phases, the magnetic coupling feature within the [Ni(dmit)(2)](-) spin dimer was explored with the broken-symmetry approach at the UBPW91/LANL2DZ level; combined with the experimental data and theoretical analyses, the relationship between the magnetic coupling nature and the stacking pattern of [Ni(dmit)(2)](-) anions as well as the origin of the phase interconversion are discussed.

The preparation, single crystal X-ray crystallography, and magnetic properties are reported for four new clusters based on [M'V(CN)8]3- octacyanometallates (M'=Mo, W). Reactions of [M'V(CN)8]3- with mononuclear NiII ions in the presence of the tmphen blocking ligand (tmphen=3,4,7,8-tetramethyl-1,10-phenanthroline) in a 2:3:6 ratio, respectively, lead to the formation of the trigonal bipyramidal clusters [NiII(tmphen)2]3[M'V(CN)8]2. Analogous reactions with the same starting materials performed in a 2:3:2 ratio, respectively, produce pentadecanuclear clusters of the type {NiII[NiII(tmphen)(MeOH)]6[Ni(H2O)3]2[micro-CN]30[WV(CN)3]6}. The W2Ni3 (1) and Mo2Ni3(2) pentanuclear clusters and the W6Ni9 (3) and Mo6Ni9 (4) pentadecanuclear molecules are isostructural to each other and crystallize in the space groups P2(1)/c and R3 respectively. Magnetic measurements indicate that the ground states for the trigonal bipyamidal clusters are S=4 as a consequence of ferromagnetic coupling with JW-Ni=9.5 cm(-1), JMo-Ni=10 cm(-1). The pentadecanuclear clusters exhibit ferromagnetic coupling as well, which leads to S=12 ground states (JW-Ni=12 cm(-1), JMo-Ni=12.2 cm(-1)). Reduced magnetization studies on the W-Ni analogues support the conclusion that they exhibit a negative axial anisotropy term; the fits give D values of -0.24 cm(-1) for the W2Ni3 cluster and D=-0.04 cm(-1)for the W6Ni9 cluster. AC susceptibility measurements indicate the beginning of an out-of-phase signal for the W2Ni3 and the W6Ni9 compounds, but detailed low temperature studies on small crystals by the microSQUID technique indicate that only the pentadecanuclear cluster exhibits hysteresis in accord with SMM behavior. Neither Mo cluster reveals any evidence for slow paramagnetic relaxation at low temperatures.

Removal of methanol molecules from the interstices of a metal-organic framework based on a 2-D hexagonal Mn(II)-TCNQF(4) net results in stronger magnetic interactions and leads to a glassy magnetically ordered state; the magnetic behavior can be reversibly cycled upon solvation-desolvation of the material.

A series of cyanide-bridged chain mixed Fe(III)/Ln(III) (Ln=Pr, Nd, Sm, Eu, Gd, Tb) complexes with the tridentate ligand 2,4,6-tri(2-pyridyl)-1,3,5-triazine (tptz) used as a capping group has been prepared. Reactions of tptz and LnCl3 with K3Fe(CN)6 yield a family of air-stable 1-D compounds {[Pr(tptz)(H2O)4Fe(CN)6].8H2O}infinity, {[Nd(tptz)(H2O)4Fe(CN)6].8H2O}infinity, {[Sm(tptz)(H2O)4Fe(CN)6].8H2O}, {[Eu(tptz)(H2O)4Fe(CN)6].6H2O}infinity, {[Gd(tptz)(H2O)4Fe(CN)6].6H2O}infinity, and {[Tb(tptz)(H2O)4Fe(CN)6].8H2O}infinity. Temperature dependent magnetic susceptibility studies of reveal that in , the Sm(III) and Fe(III) ions are ferromagnetically coupled with 3-D ordering occurring below 3.5 K. The appearance of the frequency dependent out-of-phase signal is explained in terms of an ordering with a spin glass-like behavior. To compare the magnetic behavior of with related compounds, {[Sm(tptz)(H2O)4Co(CN)6].8H2O}infinity and {[La(tptz)(DMF)(H2O)3Fe(CN)6].5H2O}infinity, {[Sm(tmphen)(DMF)3(H2O)Fe(CN)6].2H2O}infinity, {[Sm(tmphen)2(H2O)2Fe(CN)6].MeOH.13H2O}infinity and {[Sm(tmphen)2(H2O)2Cr(CN)6].MeOH.9H2O}infinity with 3,4,7,8-tetramethyl-1,10-phenanthroline (tmphen) were also prepared.

Reactions of [W(CN)(8)](3-/4-) anions with complexes of Mn(2+) ion with tridentate organic ligand 2,4,6-tris(2-pyridyl)-1,3,5-triazine (tptz) lead to a series of heterobimetallic complexes. The crystal structures of these compounds are derived from the same basic structural fragment, namely a W(2)Mn(2) square constructed of alternating cyanide-bridged W and Mn ions. In [Mn(II)(tptz)(OAc)(H(2)O)(2)](2){[Mn(II)(tptz)(MeOH)(1.58)(H(2)O)(0.42)](2)[W(V)(CN)(8)](2)}.5 MeOH.9.85 H(2)O (3), isolated molecular squares are co-crystallized with mononuclear cationic Mn(II) complexes. The structure of {[Mn(II)(tptz)(MeOH)](2)[W(IV)(CN)(8)].2 MeOH}(infinity) (4) is based on an infinite chain of vertex-sharing squares, while {[Mn(II) (2)(tptz)(2)(MeOH)(3)(OAc)][W(V)(CN)(8)].3.5 MeOH0.25 H(2)O}(infinity) (5) and {[Mn(II) (2)(tptz)(2)(MeOH)(3)W(V)(CN)(8)][Mn(II)(tptz)(MeOH)W(V)(CN)(8)].2 H(2).OMeOH}(8) (7) are derived from such an infinite chain by removing one of the W-C[triple bond]N-Mn linkages in each of the squares. The decanuclear cluster [Mn(II) (6)(tptz)(6)(MeOH)(4)(DMF)(2)W(V) (4)(CN)(32)].8.2 H(2)O.2.3 MeOH (6) is a truncated version of structure 4 and consists of three vertex-sharing W(2)Mn(2) squares. The structure of [Mn(II)(tptz)(MeOH)(NO(3))](2)[Mn(II)(tptz)(MeOH) (DMF)](2)[W(V)(CN)(8)](2).6 MeOH (8) consists of a hexanuclear cluster, in which the central W(2)Mn(2) square is extended by two Mn side-arms attached via CN(-) ligands to the W corners of the square. The magnetic behavior of these heterobimetallic complexes (except for 4) is dominated by antiferromagnetic coupling between Mn(II) and W(V) ions mediated by cyanide bridges. Compounds 3, 6, and 8 exhibit high spin ground states of S=4, 13, and 9, respectively, while 5 and 7 exhibit behavior typical of a ferrimagnetic chain with alternating spin centers. Complex 4 contains diamagnetic W(IV) centers but holds promise as a potential photomagnetic solid.