51. Intravitreal injection of conbercept for diabetic macular edema complicated with diabetic nephropathy
- Author
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Yuan-Zhang Zhu, Zhi-Zhi Dou, Wen-Ying Wang, Qing-Yue Ma, Wen-Dan Yi, Ning-Ning Yao, Yi-Chong Liu, Xiao-Di Gao, Qian Zhang, and Wen-Juan Luo
- Subjects
conbercept ,diabetic nephropathy ,diabetic macular edema ,optical coherence tomography ,Ophthalmology ,RE1-994 - Abstract
AIM: To observe the therapeutic effect of conbercept on diabetic macular edema (DME) complicated with diabetic nephropathy (DN). METHODS: In this retrospective study, 54 patients (54 eyes) that diagnosed as DME from January 2017 to October 2021 were collected. The patients were divided into two groups: DME patients with DN (25 eyes), and DME patients without DN (29 eyes). General conditions were collected before treatment, laboratory tests include fasting blood glucose, HbA1c, microalbumin/creatinine, serum creatinine. Optical coherence tomography (OCT) was used to check the ellipsoidal zone (EZ) and external limiting membrane (ELM) integrity. Central macular thickness (CMT), best corrected visual acuity (BCVA), and retinal hyperreflective foci (HF) as well as numbers of injections were recorded. RESULTS: There were significant differences between fasting blood glucose, HbA1c, serum creatinine, urinary microalbumin/creatinine, and estimated glomerular filtration rate (eGFR) between the two groups (all P
- Published
- 2024
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