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63. Nocardioides ochotonae sp. nov., Nocardioides campestrisoli sp. nov. and Nocardioides pantholopis sp. nov., isolated from the Qinghai–Tibet Plateau

Author

Zhou, Juan, primary, Wang, Xiaoxia, additional, Xu, Mingchao, additional, Yang, Jing, additional, Lai, Xin-He, additional, Jin, Dong, additional, Lu, Shan, additional, Pu, Ji, additional, Yang, Caixin, additional, Zhang, Sihui, additional, Tao, Yuanmeihui, additional, Zhang, Zehui, additional, Liu, Liyun, additional, and Xu, Jianguo, additional

Published
2022
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67. Change in willingness to COVID‐19 vaccination in China: Two online surveys during the pandemic

Author

Huang, Ninghua, primary, Wang, Chao, additional, Han, Bingfeng, additional, Zhao, Tianshuo, additional, Liu, Bei, additional, Chen, Linyi, additional, Xie, Mingzhu, additional, Zheng, Hui, additional, Zhang, Sihui, additional, Wang, Yu, additional, Juan, Du, additional, Liu, YaQiong, additional, Lu, QingBin, additional, and Cui, Fuqiang, additional

Published
2022
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68. Multifunctional Mesoporous Silica Nanoparticles Reinforced Silk Fibroin Composite with Antibacterial and Osteogenic Effects for Infectious Bone Rehabilitation

Author

Li,Dexiong, Xie,Jing, Qiu,Yubei, Zhang,Sihui, Chen,Jiang, Li,Dexiong, Xie,Jing, Qiu,Yubei, Zhang,Sihui, and Chen,Jiang

Abstract

Dexiong Li,1,* Jing Xie,1,* Yubei Qiu,1,2 Sihui Zhang,1,3 Jiang Chen1,* 1School and Hospital of Stomatology, Fujian Medical University, Fuzhou, People’s Republic of China; 2Fujian Key Laboratory of Fujian College and University, Fujian Medical University, Fuzhou, People’s Republic of China; 3Institute of Stomatology & Research Center of Dental and Craniofacial Implants, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jiang Chen, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, People’s Republic of China, Tel +86 591 83735488, Fax +86 591 83700838, Email jiangchen@fjmu.edu.cnBackground: Existing implant materials cannot meet the essential multifunctional requirements of repairing infected bone defects, such as antibacterial and osteogenesis abilities. A promising strategy to develop a versatile biomimicry composite of the natural bone structure may be accomplished by combining a multifunctional nanoparticle with an organic scaffold.Methods: In this study, a quaternary ammonium silane-modified mesoporous silica containing nano silver (Ag@QHMS) was successfully synthesized and further combined with silk fibroin (SF) to fabricate the multifunctional nano-reinforced scaffold (SF-Ag@QHMS) using the freeze-drying method. Furthermore, the antibacterial and osteogenic effects of this composite were evaluated in vitro and in vivo.Results: SF-Ag@QHMS inherited a three-dimensional porous structure (porosity rate: 91.90 ± 0.62%) and better mechanical characteristics (2.11 ± 0.06 kPa) than that of the SF scaffold (porosity rate: 91.62 ± 1.65%; mechanic strength: 2.02 ± 0.01 kPa). Simultaneously, the introduction of versatile nanoparticles has provided the composite with additional antibacterial ability against Porphyromonas gingivalis, which can be maintained for 15 days. Furthermore, the expression o

Published
2022

69. Two New Alkali/Cadmium Bimetallic Coordination Polymers: Luminescent Properties and Cancer Prevention by Regulating the Interaction Between High Mobility Group Protein B1 and Immune Cells.

Author

Zhang, Sihui, Lu, Kaijin, Shen, Xiaozhou, Ye, Yunyao, Sun, Guangzhi, Xu, Jie, and Han, Gaohua

Subjects
*HIGH mobility group proteins, *COORDINATION polymers, *CANCER prevention, *LIGANDS (Chemistry), *CADMIUM, *SPACE groups
Abstract

Two new heterometallic coordination polymers, namely {[(CH3)2NH2]3[Cd3Na3(5-NO2-ip)6(H2O)2]}n (1) and {[(CH3)2NH2][CdRb(5-NO2-ip)2]}n (2) (5-NO2-H2ip = 5-nitroisophthalic acid), have been synthesized via the solvothermal reactions of 5-NO2-H2ip and Cd(NO3)2·4H2O in the combination with NaNO3 or RbNO3. The structural analysis results exhibited that the two compounds crystallized in the monoclinic space group of C2/c and exhibit 3D anionic frameworks balanced by the disordered dimethylamine cations. Both compounds reported here show strong blue luminescence at room temperature, which may be acted as good blue luminescent materials. Their application values on the cancer prevention and treatment were evaluated, followed by the mechanism exploration. The assay of CCK-8 indicated that the 1 was much stronger than that of 2 on the inhibition of the proliferation of cancer cells. The cancer cell apoptosis was also induced by compound 1, but not compound 2. Additionally, the HMGB1 receptor relative expression in immune cells was suppressed by complex 1, which is much more excellent than compound 2. In the end, the expression levels of Bcl-2 in cancer cells were also evidently suppressed via 1. Above all, it can be concluded that the 1 was much more superior to 2 on the cancer treatment. [ABSTRACT FROM AUTHOR]

Published
2023
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74. Morphological and genomic characteristics of two novel halotolerant actinomycetes, Tomitella gaofuii sp. nov. and Tomitella fengzijianii sp. nov. isolated from bat faeces

Author

Huang, Yuyuan, primary, Yang, Jing, additional, Lu, Shan, additional, Lai, Xin-He, additional, Jin, Dong, additional, Zhou, Juan, additional, Zhang, Sihui, additional, Huang, Qianni, additional, Lv, Xianglian, additional, Zhu, Wentao, additional, Pu, Ji, additional, Huang, Ying, additional, Liu, Liyun, additional, and Xu, Jianguo, additional

Published
2022
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79. Cost-Effectiveness of Expanded Antiviral Treatment for Chronic Hepatitis B Virus Infection in China

Author

Zhang, Sihui, primary, Wang, Chao, additional, Liu, Bei, additional, Lu, Qingbin, additional, Shang, Jia, additional, Zhou, Yi-Hua, additional, Jia, Ji-Dong, additional, Xu, Xiaoyuan, additional, Rao, Huiying, additional, Han, Bingfeng, additional, Zhao, Tianshuo, additional, Chen, Linyi, additional, Xie, Mingzhu, additional, Cui, Jiahao, additional, Du, Juan, additional, Zeng, Jing, additional, Huang, Ninghua, additional, Liu, Yaqiong, additional, Zhang, Lei, additional, Zhaung, Hui, additional, and Cui, Fuqiang, additional

Published
2022
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80. The effect of occlusal disharmony on a chronic stress‐induced animal model of gut microbiota dysbiosis.

Author

Wu, Ling, Zhang, Sihui, Zhang, Mi, Wang, Xudong, Li, Shuxian, Rausch‐Fan, Xiaohui, and Chen, Jiang

Subjects
*BIOLOGICAL models, *ANIMAL behavior, *PATHOGENESIS, *ADRENOCORTICAL hormones, *GUT microbiome, *CHRONIC diseases, *ANIMAL experimentation, *MOLARS, *MAXILLA, *MALOCCLUSION, *RATS, *COMPARATIVE studies, *RESEARCH funding, *HEALTH behavior, *STATISTICAL sampling, *PSYCHOLOGICAL stress, *DISEASE complications
Abstract

Background and Objectives: Chronic stress (CS) is closely related to intestinal health. Occlusal disharmony (OD) is a risk factor for hypersensitivity to novel stress, and the relationship between OD and the intestinal system with or without other chronic stresses remains unclear. Therefore, the purpose of this study was to investigate whether OD affects the gut microbiota and the intestinal barrier in a CS‐exposed animal model. Methods: OD was induced by making a 0.5‐mm‐thick incision on the right maxillary molar. CS involved exposure to one stressor per day for 35 days. Sprague–Dawley rats were randomly divided into an untreated control group and OD‐, CS‐ and OD + CS‐treated groups. The behavioural tests, serum corticosterone level, gut microbiota composition and tight junction protein expression in colon tissue were measured on the 56th day to elucidate the effect of OD on animals under CS. Results: Significant differences in performance on behavioural tests and serum corticosterone concentrations were observed on day 56 in the OD + CS group compared with the control group. Exposure to occlusal disharmony or chronic stress resulted in a change in the composition of the gut microbiota of rats. Differences in the expression of the tight junction proteins zonula occludens‐1 and junctional adhesion molecule‐A were observed in colon tissue from the OD + CS group compared with the control group. Conclusions: We concluded that the significant changes in performance on behavioural tests, serum corticosterone concentrations and microbiota dysbiosis and tight junction protein levels induced by OD with CS may indicate that OD is a potential factor promoting gut microbiota dysbiosis. [ABSTRACT FROM AUTHOR]

Published
2023
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81. Cost‐minimization analysis of DTaP‐IPV‐Hib combination vaccine in China: A nationwide cross‐sectional study.

Author

Liu, Bei, Cao, Bing, Wang, Chao, Sun, Tao, Miao, Yudong, Zhang, Sihui, Zhao, Tianshuo, and Cui, Fuqiang

Subjects
COMBINED vaccines, VACCINATION of children, ECONOMIC impact, RENMINBI, MEDICAL care costs
Abstract

Combination vaccines can reduce the vaccination visit, simplify the vaccination schedule and efficiently improve management. This study was primarily designed to evaluate the economic impact of integrating the diphtheria‐tetanus‐acellular pertussis inactivated poliomyelitis and Haemophilus influenzae type B (DTaP‐IPV‐Hib) combination vaccine into the China National Immunization Program. A cost‐minimization analysis (CMA) compared the costs associated with direct medical, direct nonmedical, and indirect social costs in four schemes was conducted. A budgetary impact analysis assessed the alternative schemes' financial impact on the healthcare budget. Direct medical costs were extracted using a costing questionnaire and an observational time and motion chart. Direct nonmedical (cost for transportation) and indirect costs (loss of productivity) were derived from parents' questionnaires. Replacement of the current vaccination scheme with DTaP‐IPV‐Hib combination vaccine, resulted in net increases in direct medical costs of 77.64% for alternative scheme 1, 146.54% for alternative scheme 2, and 294.67% for alternative scheme 3, respectively. However, the direct nonmedical and indirect costs and the cost of the alternative schemes were 18.18%, 36.36%, and 63.64% lower than the current scheme for alternative scheme 1, alternative scheme 2, and alternative scheme 3, respectively. From the societal perspective, when compared with the current scheme, the budgetary impact of the three alternative schemes were +66 million Chinese Yuan (CNY) (4.81%), +103 million CNY (7.53%), and +305million CNY (22.35%), respectively. The CMA considered a broader perspective of social costs and indicated that the alternative schemes would result in an overall saving of parents' transportation and work loss costs to bring their children for vaccination, translating into a total cost saving of 18.18%, 36.36%, 63.64%, comparing to the current scheme. Thus, fully or partly using the DTaP‐IPV‐Hib combination vaccine is cost‐saving in the context of China. [ABSTRACT FROM AUTHOR]

Published
2023
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82. Differences in incidence and fatality of COVID‐19 by SARS‐CoV‐2 Omicron variant versus Delta variant in relation to vaccine coverage: A world‐wide review.

Author

Wang, Chao, Liu, Bei, Zhang, Sihui, Huang, Ninghua, Zhao, Tianshuo, Lu, Qing‐Bin, and Cui, Fuqiang

Subjects
SARS-CoV-2 Omicron variant, SARS-CoV-2 Delta variant, SARS-CoV-2, COVID-19, VACCINATION coverage
Abstract

We aim to evaluate the evolution differences in the incidence and case fatality rate (CFR) of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Delta and Omicron variants. The average incidence and CFRs were described between different countries. A gamma generalized linear mixed model (GLMM) was used to compare the CFRs of Delta and Omicron variants based on vaccination coverage. Totally, 50 countries were included for analyses. The incidence of coronavirus disease 2019 (COVID‐19) ranged from 0.16/100,000 to 82.95/100,000 during the Delta period and 0.03/100,000 to 440.88/100,000 during the Omicron period. The median CFRs were 8.56 (interquartile range [IQR]: 4.76–18.39) during the Delta period and 3.04 (IQR: 1.87–7.48) during the Omicron period, respectively. A total of 47 out of 50 countries showed decreased CFRs of the Omicron variant with the rate ratio ranging from 0.02 (95% confidence interval [CI]: 0.01–0.03) (in Cambodia) to 0.97 (95% CI: 0.87–1.08) (in Ireland). Gamma GLMM analysis showed that the decreased CFR was largely a result of the decreased pathogenicity of Omicron besides the increased vaccination coverage. The Omicron variant shows a higher incidence but a lower CFR around the world as a whole, which is mainly a result of the decreased pathogenicity by SARS‐CoV‐2's mutation, while the vaccination against SARS‐CoV‐2 still acts as a valuable measure in preventing people from death. [ABSTRACT FROM AUTHOR]

Published
2023
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83. Mycolicibacterium baixiangningiae sp. nov. and Mycolicibacterium mengxianglii sp. nov., two new rapidly growing mycobacterial species

Author

Cheng, Yanpeng, primary, Lei, Wenjing, additional, Wang, Xiaoxia, additional, Tian, Zhi, additional, Liu, Haican, additional, Yang, Jing, additional, Lu, Shan, additional, Lai, Xin-He, additional, Pu, Ji, additional, Huang, Ying, additional, Zhang, Sihui, additional, Yang, Caixin, additional, Lian, Xingxing, additional, Bai, Yibo, additional, Wan, Kanglin, additional, Wang, Suping, additional, and Xu, Jianguo, additional

Published
2021
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84. 12 Months Persistent Immunogenicity after Hepatitis B Vaccination in Patients with Type 2 Diabetes and Immunogenicity of Revaccination in Non-Responders: An Open-Label Randomized Controlled Trial

Author

Han, Bingfeng, primary, Liu, Wu, additional, Du, Juan, additional, Liu, Hanyu, additional, Zhao, Tianshuo, additional, Yang, Shubo, additional, Wang, Shuai, additional, Zhang, Sihui, additional, Liu, Bei, additional, Liu, Yaqiong, additional, and Cui, Fuqiang, additional

Published
2021
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85. Willingness and SARS-CoV-2 Vaccination Coverage among Healthcare Workers in China: A Nationwide Study

Author

Wang, Chao, primary, Wang, Yu, additional, Han, Bingfeng, additional, Zhao, Tian-Shuo, additional, Liu, Bei, additional, Liu, Hanyu, additional, Chen, Linyi, additional, Xie, Mingzhu, additional, Zheng, Hui, additional, Zhang, Sihui, additional, Zeng, Jing, additional, Huang, Ning-Hua, additional, Du, Juan, additional, Liu, Yaqiong, additional, Lu, Qing-Bin, additional, and Cui, Fuqiang, additional

Published
2021
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86. Identification of Haloactinobacterium kanbiaonis sp. nov. and Ruania zhangjianzhongii sp. nov., two novel species of the family Ruaniaceae isolated from faeces of bats (Hipposideros spp.)

Author

Xu, Mingchao, primary, Dai, Yan, additional, Huang, Yuyuan, additional, Yang, Jing, additional, Lai, Xin-He, additional, Jin, Dong, additional, Lu, Shan, additional, Zhou, Juan, additional, Zhang, Sihui, additional, Bai, Yibo, additional, Jiao, Yifan, additional, Qiao, Lei, additional, Jiang, Yan, additional, and Xu, Jianguo, additional

Published
2021
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87. Nocardioides dongkuii sp. nov. and Nocardioides lijunqiniae sp. nov., isolated from faeces of Tibetan antelope (Pantholops hodgsonii) and leaves of dandelion (Taraxacum officinale), respectively, on the Qinghai–Tibet Plateau

Author

Cheng, Yanpeng, primary, Jiao, Yifan, additional, Zhang, Sihui, additional, Yang, Jing, additional, Lu, Shan, additional, Jin, Dong, additional, Lai, Xin-He, additional, Pu, Ji, additional, Huang, Ying, additional, Zheng, Han, additional, Bai, Yibo, additional, Wang, Suping, additional, and Xu, Jianguo, additional

Published
2021
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88. Characterization of isolates of members of the genus Actinomyces from Marmota himalayana: description of Actinomyces faecalis sp. nov., Actinomyces respiraculi sp. nov., and Actinomyces trachealis sp. nov.

Author

Zhou, Juan, primary, Zhang, Sihui, additional, Zhang, Gui, additional, Yang, Jing, additional, Lai, Xin-He, additional, Pu, Ji, additional, Jin, Dong, additional, Lu, Shan, additional, Huang, Ying, additional, Zhu, Wentao, additional, Huang, Yuyuan, additional, Xu, Mingchao, additional, Lei, Wenjing, additional, Cheng, Yanpeng, additional, Liu, Liyun, additional, and Xu, Jianguo, additional

Published
2021
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89. Microbacterium chengjingii sp. nov. and Microbacterium fandaimingii sp. nov., isolated from bat faeces of Hipposideros and Rousettus species

Author

Zhou, Juan, primary, Huang, Yuyuan, additional, Yang, Jing, additional, Lai, Xin-He, additional, Jin, Dong, additional, Lu, Shan, additional, Pu, Ji, additional, Zhang, Sihui, additional, Zhu, Wentao, additional, Xu, Mingchao, additional, Huang, Ying, additional, Liang, Junrong, additional, Zheng, Han, additional, and Xu, Jianguo, additional

Published
2021
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92. Corynebacterium lizhenjunii sp. nov., isolated from the respiratory tract of Marmota himalayana, and Corynebacterium qintianiae sp. nov., isolated from the lung tissue of Pseudois nayaur

Author

Zhou, Juan, primary, Xu, Mingchao, additional, Guo, Wentao, additional, Yang, Jing, additional, Pu, Ji, additional, Lai, Xin-He, additional, Jin, Dong, additional, Lu, Shan, additional, Zhang, Sihui, additional, Huang, Yuyuan, additional, Zhu, Wentao, additional, Huang, Ying, additional, Zheng, Han, additional, and Xu, Jianguo, additional

Published
2021
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93. Vaccination willingness, vaccine hesitancy, and estimated coverage at the first round of COVID-19 vaccination in China: A national cross-sectional study

Author

Wang, Chao, primary, Han, Bingfeng, additional, Zhao, Tianshuo, additional, Liu, Hanyu, additional, Liu, Bei, additional, Chen, Linyi, additional, Xie, Mingzhu, additional, Liu, Jiang, additional, Zheng, Hui, additional, Zhang, Sihui, additional, Wang, Yu, additional, Huang, Ninghua, additional, Du, Juan, additional, Liu, Ya-Qiong, additional, Lu, Qing-Bin, additional, and Cui, Fuqiang, additional

Published
2021
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