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53. Comparison of adenocarcinoma and squamous cell carcinoma of the lung in terms of clinicopathological factors related to hematogenous metastasis after curative resection.

Author

Yusa, Toshikazu, primary, Yamaguchi, Yutaka, additional, Saito, Yukio, additional, Yamakawa, Hisami, additional, Obata, Sadao, additional, Shiba, Mitsutoshi, additional, Kimura, Hideki, additional, Fujisawa, Takehiko, additional, Ohwada, Hidemi, additional, and Hayashi, Yutaka, additional

Published
1990
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54. This title is unavailable for guests, please login to see more information.

Author

YUSA, Toshikazu, SHIBUYA, Kiyosi, YUSA, Toshikazu, and SHIBUYA, Kiyosi

Abstract

We investigated the outcome of thoracoscopic surgery for treatment of idiopathic spontaneous pneumothorax. Excision of the emphysematous bullae was thoracoscopically performed in 76 (92.7%) out of 82 cases planned for this thora-coscopic surgery. In the remaining six cases, axillary thoracotomy was performed because of severe pleural adhesions. The cases treated by thoracoscopic surgery were compared with those treated by axillary thoracotomy (12 cases).The bleeding volume, frequency of using analgesic agents and the postoperative hospitalization peroid were significantly less in the former than in the latter. No significant complications were observed following the thoracoscopic surgery. Recurrence of pneumothorax occurred in 6.60f the patients treated with thoracoscopic surgery. This recurrence rate was reduced to 4.3 139702608n the 70 patients who received chemical pleurodesis after the surgery. We concluded that thoracoscopic surgery followed by chemical pleurodesis is effective and safe in treatment of idiopathic spontaneous pneumothorax.

57. The Journal of the Japanese Society of Clinical Cytology

Author

YUSA, Toshikazu, primary, KADOYAMA, Hirobumi, additional, BABA, Masayuki, additional, SHIBA, Mitsutoshi, additional, SATO, Masanobu, additional, YAMAGUCHI, Yutaka, additional, HORIUCHI, Fumio, additional, OHIWA, Takashi, additional, YARITA, Tsutomu, additional, SAITO, Hiroko, additional, and OKAMOTO, Tatsuya, additional

Published
1982
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60. [Treatment of malignant pleural mesothelioma].

Author

Yusa T

Subjects
Combined Modality Therapy, Humans, Mesothelioma drug therapy, Mesothelioma radiotherapy, Mesothelioma surgery, Pleural Neoplasms drug therapy, Pleural Neoplasms radiotherapy, Pleural Neoplasms surgery, Prognosis, Hyperthermia, Induced, Mesothelioma therapy, Pleural Neoplasms therapy
Abstract

In Japan, it is predicted that mesothelioma will rapidly increase in the future. Malignant pleural mesothelioma that accounts for approximately 90% of mesothelioma as a whole has a median survival time of approximately nine months which is considered a poor prognosis. As for the treatment of this disease,extrapleural pneumonectomy or pleurectomy/decortication are available for those patients who can be surgically operated on. However, since a complete cure rate is low when only surgical treatment is performed, generally a multimodality treatment is performed wherein chemotherapy and/or radiotherapy are combined. For chemotherapy, a large-scale randomized phase III study demonstrated that a treatment using two agents: pemetrexed, which is a new multitargeted antifolate, and cisplatin is effective. Pemetrexed will be the drug of first choice for mesothelioma in the future. As other treatment methods, chemohyperthermia, treatments using various kinds of cytokines and angiogenesis inhibitors, genetic treatment and photodynamic therapy have been attempted. The current treatment results for this disease are very poor, and there has been a strong demand for establishing an effective treatment method.

Published
2007

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