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Pathologically, the lesions responsible for acute coronary syndrome (ACS) are ruptures of vulnerable plaques (and occasionally fibrous-cap erosions or calcified nodules) with a superimposed thrombosis. We aimed to clarify the clinical presentations related to the morphologies of coronary lesions of ACS using intravascular ultrasound (IVUS) and optical coherence tomography (OCT).Seventy-five culprit lesions of ACS patients were clearly assessed with IVUS and OCT. Patients were classified into two groups based on the presence or absence of a rupture of a culprit plaque as identified by OCT. Clinical characteristics and lesion morphologies were compared between the two groups. Waist circumference was significantly greater (p0.02) and prevalence of the metabolic syndrome (MS) higher (p=0.0011) in the rupture group. The prevalence of prodromal angina was higher in patients without plaque ruptures (p0.0001). Using multivariate analysis, the MS and prodromal angina were independent predictors of rupture of a culprit coronary plaque (odds ratio (OR): 27.30, p0.003 and OR: 0.04, p=0.0004, respectively). Among the components of the MS, the prevalence of abdominal obesity was a significant independent predictor of rupture of a culprit plaque (OR: 4.24, p0.02).There are two presentations related to the coronary lesion morphologies of ACS: we should understand these aspects of ACS.

Background: Acute coronary syndrome (ACS) commonly results from vulnerable plaque rupture, and occasionally results from thrombus formation in lesions without plaque rupture. The aim of the present study was to clarify the clinical features of different etiology of ACS and clinical predictors of culprit plaque rupture assessed on intravascular ultrasound (IVUS). Methods and Results: One hundred and ten ACS patients with emergent coronary angiography were classified into 2 groups based on the presence or absence of culprit plaque rupture assessed on IVUS. Clinical characteristics were compared between the 2 groups. Culprit coronary plaque rupture was observed in 60 patients (55%). Patients with plaque rupture were younger and were more likely to be male (P

A 65-year-old man who had undergone retropubic prostatectomy for prostate adenocarcinoma presented with sudden dyspnea and chest pain. Contrast-enhanced multi-slice computed tomography (MSCT) revealed thrombi in the left internal jugular vein (IJV) and in branches of the right pulmonary artery. Ultrasonography showed that the thrombus which occluded the left IJV was hypoechoic and mobile. After beginning anticoagulant therapy, he again presented with dyspnea and transient hypotension. MSCT and ultrasonography showed that the IJV thrombus had moved and caused a new embolism of the left pulmonary artery branch. This is a rare case of a patient who experienced non-catheter-related thrombosis of the IJV.

Summary Background Although the metabolic syndrome is associated with incident cardiovascular disease, low-density lipoprotein (LDL) cholesterol is a well-known risk factor for coronary atherosclerosis. The aim of this study was to clarify the clinical markers for coronary plaque vulnerability in acute coronary syndrome (ACS) patients (men) without the metabolic syndrome. Methods Consecutive Japanese men with ACS (n = 264) underwent emergent coronary angiography and B-mode carotid ultrasonography. Common carotid intima-media thickening and vascular dilatation were considered to indicate carotid artery remodeling. Patients were divided into two groups based on the number of complex plaques identified by coronary angiography. Results Abdominal obesity and low high-density lipoprotein cholesterol levels were frequently observed in overall patients with multiple complex coronary lesions. Although the metabolic syndrome was a significant independent predictor of multiple complex coronary lesions in overall ACS patients, a high LDL cholesterol level was an independent predictor in ACS patients without the metabolic syndrome. Carotid artery remodeling was an independent predictor of multiple complex coronary lesions in both overall patients and patients without the metabolic syndrome. Conclusion In ACS patients without the metabolic syndrome, high LDL cholesterol levels and carotid artery remodeling are important indicators for assessing the efficacy of aggressive treatments for secondary prevention of ACS.

The amount of data transmitted on the Internet has been increasing every year as the use of the Internet spreads, and situations that multiple streams simultaneously carry the same data often happen. For example, when multiple users access to a web site at once, their streams contain the same data. If it is possible to merge such multiple overlapped streams carry the same data into a single stream, we can use the Internet more efficiently. In this paper, we propose architecture for merging the same data streams by using reliable multicast transport. Then we applied this architecture to FTP traffic and implemented FTP proxy which transfers data by reliable multicast transport between multiple points. Furthermore, we experimented in FTP proxy and showed that FTP proxy are able to save network bandwidth when overlapped traffic occur.

The infectivity of neutralized IBDV by normal chicken serum (NCS) was detected in day-old and 3-week-old chicken spleen adherent (CSA) cells, and that of neutralized IBDV by maternal antibody (MN-Ab) was detected in 3-week-old CSA cells. Moreover, CSA cells from day-old chickens had complement receptor (CR), and CSA cells from 1-week-old had both CR and Fc receptor (FcR). However, the infectivity of neutralized IBDV by MN-Ab was confirmed on CSA cells which were blocked for FcR on CSA cells by heat-aggregated NCS (56 degrees C, 60 min). These results indicated that infection of neutralized IBDV by NCS on CSA cells occurred via CR, and neutralized IBDV by MN-Ab was infected via FcR. In day-old specific pathogen free (SPF) chickens, the antibody level in NCS treated and non-treated IBD live vaccine subcutaneously inoculated groups was higher than the levels in the MN-Ab-treated IBDV inoculated group, and detected until 28 days old. Moreover, subcutaneously inoculated chickens were protected against the challenge of wild IBDV at 21 days old, whereas subcutaneously inoculated chickens were infected with MN-Ab-treated IBD live vaccine. In commercial layers which had MN-Ab, antibody levels of subcutaneously vaccinated group were higher than both the non-vaccinated and orally vaccinated groups, and virus isolation and viral antigen were positive with high detection rates on peripheral lymphocytes of each subcutaneously vaccinated group of SPF and commercial chickens.(ABSTRACT TRUNCATED AT 250 WORDS)

In a color TV receiver employing a conventional shadow mask picture tube, only about a quarter of the emitted electron beams are used to energize the phosphor screen. For this reason, we have often experienced insufficient brightness with a large-screen color TV receiver. Phosphor material has been improved and the super black martix system has been devised to increase the brightness. These means, however, do not necessarily produce satisfying results. And if we want a brighter large-screen TV receiver, we must increase the high-voltage power.

The purpose of the investigation was to evaluate the effects of invertase during an experimental period with the mouth wash.The subjects were ten dental students that had healthy gingiva; they were divided into three groups.The first group consisted of two students as controls; the second group of four students was administered 3 drops of (124units)/10ml invertase; the third group of four students was administered 10 drops of (412units)/10ml invertase.Before the study, the subjects practiced oral hygiene for a month, and then the experiment started.The students were ordered to rinse their mouth 10ml of solution for one minute, twice a day, during the two week period. They were also asked not to perform other oral hygiene procedures.The results were obtained as follows:(1) After the 3rd day observation on volume of plaque accumulation had become statistically significant. (p

From a technical point of view, improvements of conventional color picture tubes could be regarded as having reached their limits. In this respect, we have found that the mask-focusing tube can achieve further improvements when combined with the black-matrix technique, a high-performance gun, dot screen structure, high-matrix transparency, and large gun electrode diameter. Two-fold improvements of brightness and contrast have been obtained with mask transparency twice that of conventional tubes, 22-percent higher matrix transparency, and mask-focusing. A 20-30 percent less deflection power has also been achieved with 110° deflection, neck diameter, and 1:2 mask-focusing voltage ratio. A 20-percent less spot diameter and a sharp beam distribution have been obtained by a new multistage-focusing electron gun in a delta arrangement in the 35.5-mm neck diameter.

重水製造の現場分析用として迅速簡便な熱伝導式分析装置を製作した.従来熱伝導法では測定困難であった0.1%附近め分析を可能にした.抵抗体にはサーミスターを使用して,感度を上げ,精度を±0,02%にすることがでさた.

A method is described for automatic micro-analysis of gases in metals by vacuum fusion. Determination of extracted gases is automatically performed by recording the changes of pressure of gases at constant volume by a diffusion pump (heating current is constant) after isolating each gas. A rotary McLeod gauge is devised, with a stretched platinum-resistance wire in its capillary allowing electrical measurement and automatic recording of the pressures of the gases in the courses of analysis. The McLeod gauge is automatically rotated. The automatic selection of the paths of the gases are controlled with solenoid mercury cuts by time-switches on a rotary drum. The time necessary to determining O2 and N2 in a metal sample is less than 30 minutes including the time taken for extracting the gases.

Watanabe , Y. (406th Medical General Laboratory, U.S. Army Medical Center, Japan) and O. Felsenfeld . Serological analysis of supernatant liquids of cultures of El Tor vibrios. J. Bacteriol. 85: 31–36. 1963.—Supernatant liquids of cultures of El Tor vibrios were analyzed serologically by applying the Ouchterlony agar diffusion technique. There are at least three different water-soluble antigenic components: thermolabile and exotoxin-like, thermolabile-bacterial, and thermostable-bacterial. All rabbit sera containing antibody(s) against the thermolabile exotoxin-like antigen(s) neutralized the lethal and hemolytic activities of the supernatant liquids of the cultures. These antibodies behave differently when absorbed with bacterial cells. The antihemolytic activity was not absorbed, whereas the antilethal was partially absorbed. The possibility of the existence of a nonactive toxin(s), which can stimulate production of antibodies against the lethal and hemolytic principles in the rabbit, was indicated.

The hemolysin from El Tor vibrio has been purified 300-fold with a recovery of 7%. The material is homogeneous when examined by ultracentrifugation, paper chromatography, electrophoresis, and by the immunological gel diffusion precipitation technique. Lipids account for 95% of the weight of the material; the remainder is protein, with a trace of carbohydrate.

Watanabe, Yoshikazu (U. S. Army Medical Center, Japan), and Oscar Felsenfeld . Production of vibrio El Tor toxin in a liquid medium. J. Bacteriol. 82: 43–47. 1961.—High toxin titers (as measured by mouth lethality and hemolytic activity) were obtained from culture supernatants of strains of El Tor vibrio isolated from patients in Indonesia. Cultivation of the organism in vitro revealed that the concentration of ferrous ion in the medium was critical for the production of maximal yields of toxin. Toxins produced under appropriate conditions were antigenic in rabbits and produced antibodies capable of neutralizing both the hemolytic and lethal actions in multiple proportion. Suggestive evidence has been obtained that the hemolytic and lethal toxins may be separate molecules.

病周疾患の疫学調査にCPITNを導入し, 従来の診査項目と比較検討を行った。CPITNとPDにおいては東芝従業員 (A) 本院患者 (B) 両集団とも (A) 相関係数R=0.61 (B) 相関係数R=0.86で有意に強い相関を示した (p

From a technical point of view improvements of color picture tube could be regarded as having reached their limits. In this respect we have found that the mask focusing tube can achieve this objective when they are combined with the black matrix technique, the high performance gun, dot screen structure, high matrix transparency and large electrode diameter. Two fold improvements of brightness and contrast have been obtained with two fold mask transparency, 22% higher matrix transparency and mask-focusing. 20–30% less deflection power, 70% less mask doming also have been achieved with 110 degree 36.5 mm neck diameter and 1∶2 mask focusing voltage ratio. 20% less spot diameter and sharp beam distribution have been obtained by new multi-stage focusing electron gun and delta arrangement 36.5 mm neck diameter.

We observed outbreaks of an egg drop syndrome similar to EDS-76 over the period from October, 1979 to March, 1980. A hemagglutinating virus (H-162) was isolated from the faces of a hen in a broiler breeding flock and shown to be serologically identical to the EDS-76 virus by the double immunodiffusion and hemagglutination-inhibition (HI) tests. The appearance of HI antibody to this virus was associated with the syndrome. The replication of the H-162 virus was inhibited with 5-iodo-2'-deoxyuridine and its infectivity was resistant to treatment by ethyl ether or chloroform. The virus was stable at pH 3.7 and readily filtered through membrane filters with 100 nm or greater pore sizes, but not through 50-nm filters. The virus multiplied with cytopathic effect in cultures of chick embryo liver and kidney cells and fibroblasts and chiken kidney cells. Eosinophilic inclusion bodies were observed in the nuclei of infected cells. Electron microscopy revealed typical adenovirus particles often aggregated in paracrystalline array forming a cubic lattice in the nuclei of thin-sectioned cells. The virus multiplied to high titers in the allantoic cavity of duck embryos, whereas no viral growth was shown in chicken embryos. The virus agglutinated chicken erythrocytes and the reaction was specifically inhibited with antiserum against the virus.

Summary It was found that Vibrio comma phages absorbed on filter paper maintain their lytic property for a long period of time. A mixture of four phages covering a wide range of true cholera vibrios was prepared and absorbed on filter paper disks which were stored for 4 months. These disks proved helpful in the identification of V. comma.