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353 results on '"Xu, Jinying"'

55. A DRDoS Detection and Defense Method Based on Deep Forest in the Big Data Environment

Author

Xu, Ruomeng, Cheng, Jieren, Wang, Fengkai, Tang, Xiangyan, Xu, Jinying, Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Hu, Ting, editor, Wang, Feng, editor, Li, Hongwei, editor, and Wang, Qian, editor

Published
2018
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56. Multi-source Enterprise Innovation Data Fusion Method Based on Hierarchy

Author

Xu, Jinying, Lv, Yuehua, Cheng, Jieren, Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Weikum, Gerhard, Series Editor, Sun, Xingming, editor, Pan, Zhaoqing, editor, and Bertino, Elisa, editor

Published
2018
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70. Additional file 1 of Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen–glucose deprivation conditions

Author

Xu, Jinying, Ji, Tong, Li, Guichen, Zhang, Haiying, Zheng, Yangyang, Li, Meiying, Ma, Jie, Li, Yulin, and Chi, Guangfan

Abstract

Additional file 1: Figure S1. HIF-1α (hypoxia-inducible factor 1-alpha) protein levels are not affected by lactate treatment. Western blot analysis for relative protein expression. GAPDH (glyceraldehyde-3-phosphate dehydrogenase) was used as a loading control, with semi-quantification of western blot findings representing NDRG2 expression levels. One‐way ANOVA was used for statistical comparisons. Data are expressed as means ± SD. n = 3, ns = no significance, *P < 0.05 and **P < 0.05. Figure S2. NDRG2-silenced astrocytes were susceptible to apoptosis during oxygen–glucose deprivation (OGD) with lactate treatment. (A) Gene set enrichment analysis (GSEA) profiles for GSEA and signature sets. (B) Results of annexin-V-FITC/PI assay (fluorescein isothiocyanate-annexin V/propidium iodide) followed by flow cytometric quantification. Cells stained with annexin-V-FITC+/PI- are considered early apoptotic cells; cells stained with annexin-V-FITC+/PI+ are considered late apoptotic cells. Figure S3. Schematic of the NDRG2 locus, wild-type (WT), the targeting vector, the targeted allele, and the deleted allele. The targeting vector replaces exons 2 and 6 with loxP-flanked exons 2 and 6, respectively. Figure S4. Comparison of siNDRG2 induced genes with human “MCAO (middle cerebral artery occlusion) induced” and “LPS (lipopolysaccharide) induced” specific genes identified by a previous study. The Venn diagram was generated using the “Draw Venn Diagram” website at http://bioinformatics.psb.ugent.be/webtools/Venn/ . Figure S5. Molecular docking pocket.

Published
2023
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74. A category and index hybrid (CIH) approach to measuring the level of prefabrication

Author

Lu, Weisheng, Ghansah, Frank Ato, and Xu, Jinying

Abstract

AbstractTwo generic approaches exist to measuring the level of prefabrication (LoP) in construction. One is the ‘category’ approach to indicating which prefabrication type a building adopts. Another is the ‘index’ approach to measuring the ratio of prefabrication in the total construction volume. However, existing studies still face difficulty in understanding the true picture of prefabrication in a building project by adopting either category or index approach. To address this issue, this study aims to develop a ‘category and index hybrid’ (CIH) approach to measuring the LoP holistically. Firstly, a tentative CIH model was developed. Then, the model was used to measure 15 sizeable high-rise building projects in Hong Kong, which have adopted different prefabrication components. Finally, the approach was presented to industrial stakeholders for validation via interviews on its strengths, weaknesses, and prospective applications. A strong positive correlation was revealed between Levels 0 and 1 prefabrication usage based on Pearson correlation, r. It also found that the CIH approach’s ‘category’ component allows people to quickly grasp a building’s prefabrication types, while its ‘index’ component allows a numerical understanding of prefabrication in the entire construction. The interview results denoted that the CIH approach can enable a series of meaningful applications.

Published
2023
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75. Spatial Distribution of Soil Heavy Metal Concentrations in Road-Neighboring Areas Using UAV-Based Hyperspectral Remote Sensing and GIS Technology.

Author

Gan, Wenxia, Zhang, Yuxuan, Xu, Jinying, Yang, Ruqin, Xiao, Anna, and Hu, Xiaodi

Abstract

Monitoring and restoring soil quality in areas neighboring roads affected by traffic activities require a thorough investigation of heavy metal concentrations. This study examines the spatial heterogeneity of copper (Cu) and chromium (Cr) concentrations in a 0.113 km² area adjacent to Jin-Long Avenue in Wuhan, China, using Unmanned Aerial Vehicle (UAV)-based hyperspectral remote sensing technology. Through this UAV-based remote sensing technology, we innovatively achieve a small-scale and fine-grained analysis of soil heavy metal pollution related with traffic activities, which represents a major contribution of this research study. In our approach, we generated 4375 spectral variates by transforming the original spectrum. To enhance result accuracy, we applied the Boruta algorithm and correlation analysis to select optimal spectral variates. We developed the retrieval model using the Gradient Boosting Decision Tree (GBDT) regression method, selected from a set of four regression methods using the LOOCV method. The resulting model yielded R-square values of 0.325 and 0.351 for Cu and Cr, respectively, providing valuable insights into the heavy metal concentrations. Based on the retrieved heavy metal concentrations from bare soil pixels (17,420 points), we analyzed the relationship between heavy metal concentrations and the perpendicular distance from the road. Additionally, we employed the universal kriging interpolation method to map heavy metal concentrations across the entire area. Our findings reveal that the concentration of heavy metals in this area exceeds background values and decreases as the distance from the road increases. This research significantly contributes to the understanding of spatial distribution characteristics and pollution caused by heavy metal concentrations resulting from traffic activities. [ABSTRACT FROM AUTHOR]

Published
2023
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91. Efficient Treatment of the Sweet Potato Starch Wastewater by Enhanced Flocculation–Coagulation of Environmentally Benign Materials

Author

Zhang, Yalan, primary, Li, Meng, additional, Zhang, Guihai, additional, Liu, Wei, additional, Xu, Jinying, additional, Tian, Yuansong, additional, Wang, Yinfeng, additional, Xie, Xingyue, additional, Peng, Zhiqi, additional, Li, Aimin, additional, Zhang, Ru, additional, Wu, Daise, additional, and Xie, Xianchuan, additional

Published
2022
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95. Retinal Dysfunction In Alzheimer’s Disease And Implications For Biomarkers

Author

Liao, Chunyan, Xu, Jinying, Chen, Yu, Ip, Yuk-yu, Nancy, Liao, Chunyan, Xu, Jinying, Chen, Yu, and Ip, Yuk-yu, Nancy

Abstract

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that manifests as cognitive deficits and memory decline, especially in old age. Several biomarkers have been developed to monitor AD progression. Given that the retina and brain share some similarities including features related to anatomical composition and neurological functions, the retina is closely associated with the progression of AD. Herein, we review the evidence of retinal dysfunction in AD, particularly at the early stage, together with the underlying molecular mechanisms. Furthermore, we compared the retinal pathologies of AD and other ophthalmological diseases and summarized potential retinal biomarkers measurable by existing technologies for detecting AD, providing insights for the future development of diagnostic tools. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Published
2021

96. Regulation of neurotransmitters by the gut microbiota and effects on cognition in neurological disorders

Author

Chen, Yijing, Xu, Jinying, Chen, Yu, Chen, Yijing, Xu, Jinying, and Chen, Yu

Abstract

Emerging evidence indicates that gut microbiota is important in the regulation of brain activity and cognitive functions. Microbes mediate communication among the metabolic, peripheral immune, and central nervous systems via the microbiota–gut–brain axis. However, it is not well understood how the gut microbiome and neurons in the brain mutually interact or how these interactions affect normal brain functioning and cognition. We summarize the mechanisms whereby the gut microbiota regulate the production, transportation, and functioning of neurotransmitters. We also discuss how microbiome dysbiosis affects cognitive function, especially in neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Published
2021

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