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52. Correlations of neutron multiplicity and γ -ray multiplicity with fragment mass and total kinetic energy in spontaneous fission of Cf 252

Author

Wang, T, Li, G, Zhu, L, Meng, Q, Wang, L, Han, H, Zhang, W, Xia, H, Hou, L, Vogt, R, and Randrup, J

Subjects
nucl-ex, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics
Abstract

The dependence of correlations of neutron multiplicity ν and γ-ray multiplicity Mγ in spontaneous fission of Cf252 on fragment mass A∗ and total kinetic energy (TKE) have been investigated by employing the ratio of Mγ/ν and the form of Mγ(ν). We show for the first time that Mγ and ν have a complex correlation for heavy fragment masses, while there is a positive dependence of Mγ for light fragment masses and for near-symmetric mass splits. The ratio Mγ/ν exhibits strong shell effects for neutron magic number N=50 and near doubly magic number shell closure at Z=50 and N=82. The γ-ray multiplicity Mγ has a maximum for TKE=165-170 MeV. Above 170 MeV Mγ(TKE) is approximately linear, while it deviates significantly from a linear dependence at lower TKE. The correlation between the average neutron and γ-ray multiplicities can be partly reproduced by model calculations.

Published
2016

53. Three-dimensional fluid motion in Faraday waves: creation of vorticity and generation of two-dimensional turbulence

Author

Francois, N., Xia, H., Punzmann, H., Ramsden, S., and Shats, M.

Subjects
Physics - Fluid Dynamics
Abstract

We study the generation of 2D turbulence in Faraday waves by investigating the creation of spatially periodic vortices in this system. Measurements which couple a diffusing light imaging technique and particle tracking algorithms allow the simultaneous observation of the three-dimensional fluid motion and of the temporal changes in the wave field topography. Quasi-standing waves are found to coexist with a spatially extended fluid transport. More specifically, the destruction of regular patterns of oscillons coincides with the emergence of a complex fluid motion whose statistics are similar to that of two-dimensional turbulence. We reveal that a lattice of oscillons generates vorticity at the oscillon scale in the horizontal flow. The interaction of these vortices explain how 2D turbulence is fueled by almost standing waves. Remarkably, the curvature of Lagrangian trajectories reveals a "footprint" of the forcing scale vortices in fully developed turbulence. 2D Navier-Stokes turbulence should be considered a source of disorder in Faraday waves. These findings also provide a new paradigm for vorticity creation in 2D flows.

Published
2014
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54. Taylor particle dispersion during transition to fully developed two-dimensional turbulence

Author

Xia, H., Francois, N., Punzmann, H., and Shats, M.

Subjects
Physics - Fluid Dynamics
Abstract

We report new measurements of single particle dispersion in turbulent two-dimensional (2D) flows. Laboratory experiments in electromagnetically driven and Faraday wave driven turbulence reveal a transition from weakly dispersing superdiffusive regime to strongly dispersing Brownian diffusion as the flow energy is increased in a broad range. The transition to fully developed 2D turbulence is characterized by the topological changes in the fluid particle trajectories and the development of self-similar diffusion. The degree of 2D turbulence development can be quantified by a parameter describing the deviation of single particle dispersion from the Taylor dispersion., Comment: 5 pages, 4 figures

Published
2014
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55. ANGPTL8 Gene Polymorphism rs2278426 Is Related to Carotid Intima–Media Thickness in T2DM

Author

Guo C, Zhao L, Ding Y, Zhao Z, Wang C, Li L, Cai Z, Li Y, Xia H, Zhu ZZ, Yu F, Dai M, Deng X, and Yuan G

Subjects
type 2 diabetes mellitus, angiopoietin‑like protein 8, carotid intima-media thickness, polymorphism, rs2278426, Specialties of internal medicine, RC581-951
Abstract

Chang Guo, Li Zhao, Yi Ding, Zhicong Zhao, Chenxi Wang, Lian Li, Zhensheng Cai, Yanyan Li, Hong Xia, ZhuanZhuan Zhu, Fan Yu, Meiqing Dai, Xia Deng, Guoyue Yuan Department of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212001, People’s Republic of ChinaCorrespondence: Guoyue YuanDepartment of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, People’s Republic of ChinaTel +86-135-0528-9352Email yuanguoyue@ujs.edu.cnXia DengDepartment of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212001, People’s Republic of ChinaEmail dengxia11@outlook.comAim: ANGPTL8 is a cytokine expressed and secreted by liver and adipose tissue, and is involved in glucose, lipid, and energy metabolism. Although studies have shown that ANGPTL8 is elevated in type 2 diabetes mellitus (T2DM) and cardiovascular disease, few have examined the association between ANGPTL8 single-nucleotide polymorphisms and the risk of macrovascular complications in T2DM patients. This study aimed to explore the relationship between rs2278426 and carotid intima–media thickening (cIMT) in T2DM.Methods: A total of 217 T2DM patients and 201 healthy control subjects with normal glucose tolerance were recruited in the study. T2DM patients were divided into two groups: T2DM patients without cIM thickening (cIMT < 1 mm, 109 cases) and T2DM patients with cIM thickening (cIMT ≥ 1 mm, 108 cases). rs2278426 genotypes in all 418 subjects were determined and the risk of T2DM and T2DM with cIM thickening analyzed.Results: CT+TT-genotype frequency in T2DM was higher than in controls with normal glucose tolerance, and the proportion of the CT+TT genotype in the group with cIMT was higher than in the group (P< 0.05). In addition, T alleles were associated with waist:hip ratio, triglycerides, high density–lipoprotein cholesterol, plasma glucose at 2 hours’ oral glucose tolerance, and homeostatic model assessment of insulin resistance (P< 0.05).Conclusion: Generally, carriers of the T allele at rs2278426 are more likely to develop T2DM, and the risk of cIM thickening is significantly increased for T-allele carriers with T2DM, which indicates an increased risk of macroangiopathy.Keywords: type 2 diabetes mellitus, angiopoietin‑like protein 8, carotid intima–media thickness, polymorphism, rs2278426

Published
2020

56. Higher Serum Asprosin Level is Associated with Urinary Albumin Excretion and Renal Function in Type 2 Diabetes

Author

Deng X, Zhao L, Guo C, Yang L, Wang D, Li Y, Xia H, Wang C, Cai Z, Li L, Zhao Z, and Yuan G

Subjects
asprosin, type 2 diabetes mellitus, diabetic nephropathy, Specialties of internal medicine, RC581-951
Abstract

Xia Deng, Li Zhao, Chang Guo, Ling Yang, Dong Wang, Yanyan Li, Hong Xia, Chenxi Wang, Zhensheng Cai, Lian Li, Zhicong Zhao, Guoyue Yuan Department of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, People’s Republic of ChinaCorrespondence: Guoyue Yuan; Zhicong ZhaoDepartment of Endocrinology, Affiliated Hospital of Jiangsu University, 438 Jiefang Road, Zhenjiang, Jiangsu 212001, People’s Republic of ChinaTel +86-13505289352; +86-18752965615Email yuanguoyue@ujs.edu.cn; 2211517025@stmail.ujs.edu.cnAim: We detected whether serum asprosin levels play a role in the occurrence and development of albuminuria in patients with type 2 diabetes mellitus (T2DM), which has not been previously discussed.Methods: Based on urinary albumin/creatinine ratio (UACR), 207 T2DM patients were divided into T2DM patients with normoalbuminuria (UACR< 30 mg/g), microalbuminuria (30≤UACR< 300 mg/g), and macroalbuminuria (UACR≥ 300 mg/g). Serum asprosin levels were determined by enzyme-linked immunosorbent assay.Results: Comparatively, the serum asprosin levels in T2DM patient groups with macroalbuminuria [2.37 (1.63– 3.57)] and microalbuminuria [2.10 (1.60– 2.90)] were significantly increased than the normoalbuminuria group [1.59 (1.18– 2.09)] (P< 0.001). Importantly, the serum level of asprosin was positively correlated with UACR (r=0.304, P< 0.001), creatinine (r=0.157, P=0.024), blood urea nitrogen (BUN) (r=0.244, P< 0.001), and negatively with glomerular filtration rate (eGFR) (r=− 0.159, P=0.022). Furthermore, multiple stepwise regression analyses showed that asprosin was significantly and independently related to UACR, BUN, DBP, and LDL-C (P< 0.05). Besides, after adjustment for the confounders, the serum asprosin level was constantly and independently associated with the development of albuminuria in T2DM patients [OR (95% CI): 2.003 (1.37∼ 2.928), P < 0.001].Conclusion: Obviously, the serum asprosin level was independently correlated with UACR in T2DM patients, which implies circulating asprosin may play an essential role in the pathogenesis of diabetic nephropathy.Keywords: asprosin, type 2 diabetes mellitus, diabetic nephropathy

Published
2020

58. Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)

Author

Kuhn, J, Abe, J, Adkins, S, Alkhovsky, S, Avsic-Zupanc, T, Ayllon, M, Bahl, J, Balkema-Buschmann, A, Ballinger, M, Baranwal, V, Beer, M, Bejerman, N, Bergeron, E, Biedenkopf, N, Blair, C, Blasdell, K, Blouin, A, Bradfute, S, Briese, T, Brown, P, Buchholz, U, Buchmeier, M, Bukreyev, A, Burt, F, Buttner, C, Calisher, C, Cao, M, Casas, I, Chandran, K, Charrel, R, Chaturvedi, K, Chooi, K, Crane, A, Bo, E, de la Torre, J, de Souza, W, de Swart, R, Debat, H, Dheilly, N, Di Paola, N, Di Serio, F, Dietzgen, R, Digiaro, M, Drexler, J, Duprex, W, Durrwald, R, Easton, A, Elbeaino, T, Ergunay, K, Feng, G, Firth, A, Fooks, A, Formenty, P, Freitas-Astua, J, Gago-Zachert, S, Garcia, M, Garcia-Sastre, A, Garrison, A, Gaskin, T, Gong, W, Gonzalez, J, de Bellocq, J, Griffiths, A, Groschup, M, Gunther, I, Gunther, S, Hammond, J, Hasegawa, Y, Hayashi, K, Hepojoki, J, Higgins, C, Hongo, S, Horie, M, Hughes, H, Hume, A, Hyndman, T, Ikeda, K, Jiang, D, Jonson, G, Junglen, S, Klempa, B, Klingstrom, J, Kondo, H, Koonin, E, Krupovic, M, Kubota, K, Kurath, G, Laenen, L, Lambert, A, Li, J, Liu, R, Lukashevich, I, Macdiarmid, R, Maes, P, Marklewitz, M, Marshall, S, Marzano, S, Mccauley, J, Mirazimi, A, Muhlberger, E, Nabeshima, T, Naidu, R, Natsuaki, T, Navarro, B, Navarro, J, Neriya, Y, Netesov, S, Neumann, G, Nowotny, N, Nunes, M, Ochoa-Corona, F, Okada, T, Palacios, G, Pallas, V, Papa, A, Paraskevopoulou, S, Parrish, C, Pauvolid-Correa, A, Paweska, J, Perez, D, Pfaff, F, Plemper, R, Postler, T, Rabbidge, L, Radoshitzky, S, Ramos-Gonzalez, P, Rehanek, M, Resende, R, Reyes, C, Rodrigues, T, Romanowski, V, Rubbenstroth, D, Rubino, L, Runstadler, J, Sabanadzovic, S, Sadiq, S, Salvato, M, Sasaya, T, Schwemmle, M, Sharpe, S, Shi, M, Shimomoto, Y, Sidharthan, V, Sironi, M, Smither, S, Song, J, Spann, K, Spengler, J, Stenglein, M, Takada, A, Takeyama, S, Tatara, A, Tesh, R, Thornburg, N, Tian, X, Tischler, N, Tomitaka, Y, Tomonaga, K, Tordo, N, Tu, C, Turina, M, Tzanetakis, I, Vaira, A, van den Hoogen, B, Vanmechelen, B, Vasilakis, N, Verbeek, M, von Bargen, S, Wada, J, Wahl, V, Walker, P, Waltzek, T, Whitfield, A, Wolf, Y, Xia, H, Xylogianni, E, Yanagisawa, H, Yano, K, Ye, G, Yuan, Z, Zerbini, F, Zhang, G, Zhang, S, Zhang, Y, Zhao, L, Okland, A, Kuhn J. H., Abe J., Adkins S., Alkhovsky S. V., Avsic-Zupanc T., Ayllon M. A., Bahl J., Balkema-Buschmann A., Ballinger M. J., Baranwal V. K., Beer M., Bejerman N., Bergeron E., Biedenkopf N., Blair C. D., Blasdell K. R., Blouin A. G., Bradfute S. B., Briese T., Brown P. A., Buchholz U. J., Buchmeier M. J., Bukreyev A., Burt F., Buttner C., Calisher C. H., Cao M., Casas I., Chandran K., Charrel R. N., Chaturvedi K. K., Chooi K. M., Crane A., Bo E. D., de la Torre J. C., de Souza W. M., de Swart R. L., Debat H., Dheilly N. M., Di Paola N., Di Serio F., Dietzgen R. G., Digiaro M., Drexler J. F., Duprex W. P., Durrwald R., Easton A. J., Elbeaino T., Ergunay K., Feng G., Firth A. E., Fooks A. R., Formenty P. B. H., Freitas-Astua J., Gago-Zachert S., Garcia M. L., Garcia-Sastre A., Garrison A. R., Gaskin T. R., Gong W., Gonzalez J. -P. J., de Bellocq J., Griffiths A., Groschup M. H., Gunther I., Gunther S., Hammond J., Hasegawa Y., Hayashi K., Hepojoki J., Higgins C. M., Hongo S., Horie M., Hughes H. R., Hume A. J., Hyndman T. H., Ikeda K., Jiang D., Jonson G. B., Junglen S., Klempa B., Klingstrom J., Kondo H., Koonin E. V., Krupovic M., Kubota K., Kurath G., Laenen L., Lambert A. J., Li J., Li J. -M., Liu R., Lukashevich I. S., MacDiarmid R. M., Maes P., Marklewitz M., Marshall S. H., Marzano S. -Y. L., McCauley J. W., Mirazimi A., Muhlberger E., Nabeshima T., Naidu R., Natsuaki T., Navarro B., Navarro J. A., Neriya Y., Netesov S. V., Neumann G., Nowotny N., Nunes M. R. T., Ochoa-Corona F. M., Okada T., Palacios G., Pallas V., Papa A., Paraskevopoulou S., Parrish C. R., Pauvolid-Correa A., Paweska J. T., Perez D. R., Pfaff F., Plemper R. K., Postler T. S., Rabbidge L. O., Radoshitzky S. R., Ramos-Gonzalez P. L., Rehanek M., Resende R. O., Reyes C. A., Rodrigues T. C. S., Romanowski V., Rubbenstroth D., Rubino L., Runstadler J. A., Sabanadzovic S., Sadiq S., Salvato M. S., Sasaya T., Schwemmle M., Sharpe S. R., Shi M., Shimomoto Y., Sidharthan V. K., Sironi M., Smither S., Song J. -W., Spann K. M., Spengler J. R., Stenglein M. D., Takada A., Takeyama S., Tatara A., Tesh R. B., Thornburg N. J., Tian X., Tischler N. D., Tomitaka Y., Tomonaga K., Tordo N., Tu C., Turina M., Tzanetakis I. E., Vaira A. M., van den Hoogen B., Vanmechelen B., Vasilakis N., Verbeek M., von Bargen S., Wada J., Wahl V., Walker P. J., Waltzek T. B., Whitfield A. E., Wolf Y. I., Xia H., Xylogianni E., Yanagisawa H., Yano K., Ye G., Yuan Z., Zerbini F. M., Zhang G., Zhang S., Zhang Y. -Z., Zhao L., Okland A. L., Kuhn, J, Abe, J, Adkins, S, Alkhovsky, S, Avsic-Zupanc, T, Ayllon, M, Bahl, J, Balkema-Buschmann, A, Ballinger, M, Baranwal, V, Beer, M, Bejerman, N, Bergeron, E, Biedenkopf, N, Blair, C, Blasdell, K, Blouin, A, Bradfute, S, Briese, T, Brown, P, Buchholz, U, Buchmeier, M, Bukreyev, A, Burt, F, Buttner, C, Calisher, C, Cao, M, Casas, I, Chandran, K, Charrel, R, Chaturvedi, K, Chooi, K, Crane, A, Bo, E, de la Torre, J, de Souza, W, de Swart, R, Debat, H, Dheilly, N, Di Paola, N, Di Serio, F, Dietzgen, R, Digiaro, M, Drexler, J, Duprex, W, Durrwald, R, Easton, A, Elbeaino, T, Ergunay, K, Feng, G, Firth, A, Fooks, A, Formenty, P, Freitas-Astua, J, Gago-Zachert, S, Garcia, M, Garcia-Sastre, A, Garrison, A, Gaskin, T, Gong, W, Gonzalez, J, de Bellocq, J, Griffiths, A, Groschup, M, Gunther, I, Gunther, S, Hammond, J, Hasegawa, Y, Hayashi, K, Hepojoki, J, Higgins, C, Hongo, S, Horie, M, Hughes, H, Hume, A, Hyndman, T, Ikeda, K, Jiang, D, Jonson, G, Junglen, S, Klempa, B, Klingstrom, J, Kondo, H, Koonin, E, Krupovic, M, Kubota, K, Kurath, G, Laenen, L, Lambert, A, Li, J, Liu, R, Lukashevich, I, Macdiarmid, R, Maes, P, Marklewitz, M, Marshall, S, Marzano, S, Mccauley, J, Mirazimi, A, Muhlberger, E, Nabeshima, T, Naidu, R, Natsuaki, T, Navarro, B, Navarro, J, Neriya, Y, Netesov, S, Neumann, G, Nowotny, N, Nunes, M, Ochoa-Corona, F, Okada, T, Palacios, G, Pallas, V, Papa, A, Paraskevopoulou, S, Parrish, C, Pauvolid-Correa, A, Paweska, J, Perez, D, Pfaff, F, Plemper, R, Postler, T, Rabbidge, L, Radoshitzky, S, Ramos-Gonzalez, P, Rehanek, M, Resende, R, Reyes, C, Rodrigues, T, Romanowski, V, Rubbenstroth, D, Rubino, L, Runstadler, J, Sabanadzovic, S, Sadiq, S, Salvato, M, Sasaya, T, Schwemmle, M, Sharpe, S, Shi, M, Shimomoto, Y, Sidharthan, V, Sironi, M, Smither, S, Song, J, Spann, K, Spengler, J, Stenglein, M, Takada, A, Takeyama, S, Tatara, A, Tesh, R, Thornburg, N, Tian, X, Tischler, N, Tomitaka, Y, Tomonaga, K, Tordo, N, Tu, C, Turina, M, Tzanetakis, I, Vaira, A, van den Hoogen, B, Vanmechelen, B, Vasilakis, N, Verbeek, M, von Bargen, S, Wada, J, Wahl, V, Walker, P, Waltzek, T, Whitfield, A, Wolf, Y, Xia, H, Xylogianni, E, Yanagisawa, H, Yano, K, Ye, G, Yuan, Z, Zerbini, F, Zhang, G, Zhang, S, Zhang, Y, Zhao, L, Okland, A, Kuhn J. H., Abe J., Adkins S., Alkhovsky S. V., Avsic-Zupanc T., Ayllon M. A., Bahl J., Balkema-Buschmann A., Ballinger M. J., Baranwal V. K., Beer M., Bejerman N., Bergeron E., Biedenkopf N., Blair C. D., Blasdell K. R., Blouin A. G., Bradfute S. B., Briese T., Brown P. A., Buchholz U. J., Buchmeier M. J., Bukreyev A., Burt F., Buttner C., Calisher C. H., Cao M., Casas I., Chandran K., Charrel R. N., Chaturvedi K. K., Chooi K. M., Crane A., Bo E. D., de la Torre J. C., de Souza W. M., de Swart R. L., Debat H., Dheilly N. M., Di Paola N., Di Serio F., Dietzgen R. G., Digiaro M., Drexler J. F., Duprex W. P., Durrwald R., Easton A. J., Elbeaino T., Ergunay K., Feng G., Firth A. E., Fooks A. R., Formenty P. B. H., Freitas-Astua J., Gago-Zachert S., Garcia M. L., Garcia-Sastre A., Garrison A. R., Gaskin T. R., Gong W., Gonzalez J. -P. J., de Bellocq J., Griffiths A., Groschup M. H., Gunther I., Gunther S., Hammond J., Hasegawa Y., Hayashi K., Hepojoki J., Higgins C. M., Hongo S., Horie M., Hughes H. R., Hume A. J., Hyndman T. H., Ikeda K., Jiang D., Jonson G. B., Junglen S., Klempa B., Klingstrom J., Kondo H., Koonin E. V., Krupovic M., Kubota K., Kurath G., Laenen L., Lambert A. J., Li J., Li J. -M., Liu R., Lukashevich I. S., MacDiarmid R. M., Maes P., Marklewitz M., Marshall S. H., Marzano S. -Y. L., McCauley J. W., Mirazimi A., Muhlberger E., Nabeshima T., Naidu R., Natsuaki T., Navarro B., Navarro J. A., Neriya Y., Netesov S. V., Neumann G., Nowotny N., Nunes M. R. T., Ochoa-Corona F. M., Okada T., Palacios G., Pallas V., Papa A., Paraskevopoulou S., Parrish C. R., Pauvolid-Correa A., Paweska J. T., Perez D. R., Pfaff F., Plemper R. K., Postler T. S., Rabbidge L. O., Radoshitzky S. R., Ramos-Gonzalez P. L., Rehanek M., Resende R. O., Reyes C. A., Rodrigues T. C. S., Romanowski V., Rubbenstroth D., Rubino L., Runstadler J. A., Sabanadzovic S., Sadiq S., Salvato M. S., Sasaya T., Schwemmle M., Sharpe S. R., Shi M., Shimomoto Y., Sidharthan V. K., Sironi M., Smither S., Song J. -W., Spann K. M., Spengler J. R., Stenglein M. D., Takada A., Takeyama S., Tatara A., Tesh R. B., Thornburg N. J., Tian X., Tischler N. D., Tomitaka Y., Tomonaga K., Tordo N., Tu C., Turina M., Tzanetakis I. E., Vaira A. M., van den Hoogen B., Vanmechelen B., Vasilakis N., Verbeek M., von Bargen S., Wada J., Wahl V., Walker P. J., Waltzek T. B., Whitfield A. E., Wolf Y. I., Xia H., Xylogianni E., Yanagisawa H., Yano K., Ye G., Yuan Z., Zerbini F. M., Zhang G., Zhang S., Zhang Y. -Z., Zhao L., and Okland A. L.

Abstract

In April 2023, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by one new family, 14 new genera, and 140 new species. Two genera and 538 species were renamed. One species was moved, and four were abolished. This article presents the updated taxonomy of Negarnaviricota as now accepted by the ICTV

Published
2023

59. Inverse energy cascade and emergence of large coherent vortices in turbulence driven by Faraday waves

Author

Francois, N., Xia, H., Punzmann, H., and Shats, M.

Subjects
Physics - Fluid Dynamics
Abstract

We report the generation of large coherent vortices via inverse energy cascade in Faraday wave driven turbulence. The motion of floaters in the Faraday waves is three dimensional but its horizontal velocity fluctuations show unexpected similarity with two-dimensional turbulence. The inverse cascade is detected by measuring frequency spectra of the Lagrangian velocity, and it is confirmed by computing the third moment of the horizontal velocity fluctuations. This is observed in deep water in a broad range of wavelengths. The results broaden the scope of recent findings on Faraday waves in thin layers [A. von Kameke, \textit{et al.}, \textit{Phys. Rev. Lett.} \textbf{107}, 074502 (2011)]., Comment: 5 pages, 5 figures

Published
2013
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64. Robust inverse energy cascade and turbulence structure in three-dimensional layers of fluid

Author

Byrne, D., Xia, H., and Shats, M.

Subjects
Physics - Fluid Dynamics
Abstract

Here we report the first evidence of the inverse energy cascade in a flow dominated by 3D motions. Experiments are performed in thick fluid layers where turbulence is driven electromagnetically. It is shown that if the free surface of the layer is not perturbed, the top part of the layer behaves as quasi-2D and supports the inverse energy cascade regardless of the layer thickness. Well below the surface the cascade survives even in the presence of strong 3D eddies developing when the layer depth exceeds half the forcing scale. In a bounded flow at low bottom dissipation, the inverse energy cascade leads to the generation of a spectral condensate below the free surface. Such coherent flow can destroy 3D eddies in the bulk of the layer and enforce the flow planarity over the entire layer thickness., Comment: 8 pages, 6 figures

Published
2011
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65. Turbulence damping as a measure of the flow dimensionality

Author

Shats, M., Byrne, D., and Xia, H.

Subjects
Physics - Fluid Dynamics, Nonlinear Sciences - Adaptation and Self-Organizing Systems
Abstract

The dimensionality of turbulence in fluid layers determines their properties. We study electromagnetically driven flows in finite depth fluid layers and show that eddy viscosity, which appears as a result of three-dimensional motions, leads to increased bottom damping. The anomaly coefficient, which characterizes the deviation of damping from the one derived using a quasi-two-dimensional model, can be used as a measure of the flow dimensionality. Experiments in turbulent layers show that when the anomaly coefficient becomes high, the turbulent inverse energy cascade is suppressed. In the opposite limit turbulence can self-organize into a coherent flow., Comment: 4 pages, 4 figures

Published
2010
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66. Modulation instability and capillary wave turbulence

Author

Xia, H., Shats, M., and Punzmann, H.

Subjects
Physics - Fluid Dynamics, Nonlinear Sciences - Pattern Formation and Solitons
Abstract

Formation of turbulence of capillary waves is studied in laboratory experiments. The spectra show multiple exponentially decreasing harmonics of the parametrically excited wave which nonlinearly broaden with the increase in forcing. Spectral broadening leads to the development of the spectral continuum which scales as $\propto f^{-2.8}$, in agreement with the weak turbulence theory (WTT) prediction. Modulation instability of capillary waves is shown to be responsible for the transition from discrete to broadband spectrum. The instability leads to spectral broadening of the harmonics, randomization of their phases, it isolates the wave field from the wall, eventually allows the transition from 4- to 3-wave interactions as the dominant nonlinear process, thus creating the prerequisites assumed in WTT., Comment: 6 pages, 5 figures

Published
2010
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67. Capillary rogue waves

Author

Shats, M., Punzmann, H., and Xia, H.

Subjects
Physics - Fluid Dynamics
Abstract

We report the first observation of extreme wave events (rogue waves) in parametrically driven capillary waves. Rogue waves are observed above a certain threshold in forcing. Above this threshold, frequency spectra broaden and develop exponential tails. For the first time we present evidence of strong four-wave coupling in non-linear waves (high tricoherence), which points to modulation instability as the main mechanism in rogue waves. The generation of rogue waves is identified as the onset of a distinct tail in the probability density function of the wave heights. Their probability is higher than expected from the measured wave background., Comment: 4 pages, 5 figures

Published
2010
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68. Phase randomization of three-wave interactions in capillary waves

Author

Punzmann, H., Shats, M. G., and Xia, H.

Subjects
Physics - Fluid Dynamics
Abstract

We present new experimental results on the transition from the coherent-phase to the random-phase three-wave interactions in capillary waves under parametric excitation. Above the excitation threshold, coherent wave harmonics spectrally broaden. An increase in the pumping amplitude increases spectral widths of wave harmonics and eventually causes a strong decrease in the degree of the three-wave phase coupling. The results point to the modulation instability of capillary waves, which leads to breaking of continuous waves into ensembles of short-lived wavelets or envelope solitons, as the reason for the phase randomization of three-wave interactions., Comment: 4 pages, 5 figures, accepted 17July09 for publication in PRL

Published
2009
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70. Analysis of the effect of elevated systemic immuno-inflammation index on hepatic steatosis based on the NHANES database.

Author

XIA, H. J., HE, J., ZHANG, D. W., and DING, X.

Abstract

OBJECTIVE: Based on data from the National Health and Nutrition Examination Survey (NHANES), this study aimed to investigate the effect of high levels of systemic immune inflammation (SII) on hepatic steatosis by conducting a population-based cross-sectional survey of research subjects. SUBJECTS AND METHODS: The population included 5,119 participants from the NHANES 2017-2020 cycle who were selected as the research subjects. We used (neutrophil count x platelet count)/lymphocyte count as the formula for calculating SII. The formula for calculating HSI levels was 8 x the ratio of [alanine aminotransferase (ALT) / aspartate aminotransferase (AST)] + body mass index (BMI) + 2 (with diabetes mellitus) + 2 (for women). HSI=36 was taken as the cut-off value for evaluating hepatic steatosis. Multivariate logistic regression analysis was used to evaluate the relationship between hepatic steatosis and SII in different models. Subgroup analysis was used to explore the relationship between different subgroups of SII and hepatic steatosis. Interaction analyses were used to assess the heterogeneity. RESULTS: Out of a total of 5,119 participants, hepatic steatosis was observed in 2,742 individuals. Multivariate logistic regression showed that the independent risk factor for hepatic steatosis was a high SII level (OR=1.33, 95% CI: 1.11-1.49, p<0.05). After adjusting for differences in BMI and HSI using propensity score matching (PSM), bariatric surgery also reduced SII risk. CONCLUSIONS: T here i s a c orrelation b etween SII and hepatic steatosis, and bariatric surgery can effectively reduce SII risk in the hepatic steatosis population. [ABSTRACT FROM AUTHOR]

Published
2024

74. Antimicrobial Resistance And Molecular Characteristics Among Neisseria gonorrhoeae Clinical Isolates In A Chinese Tertiary Hospital

Author

Zheng Z, Liu L, Shen X, Yu J, Chen L, Zhan L, Chen H, Lin C, Jiang Y, Xia H, Wang L, and Yu F

Subjects
Neisseria gonorrhoeae, azithromycin, antimicrobial resistance, NG-MAST, MLST., Infectious and parasitic diseases, RC109-216
Abstract

Zhou Zheng,1 Li Liu,1 Xiaofei Shen,1 Jingyi Yu,1 Lijiang Chen,1 Lingling Zhan,1 Han Chen,1 Chunchan Lin,1 Ye Jiang,1 Hong Xia,1 Liangxing Wang,2 Fangyou Yu1,3 1Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Department of Respiratory Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, People’s Republic of China; 3Department of Laboratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200443, People’s Republic of ChinaCorrespondence: Fangyou YuDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of ChinaEmail wzjxyfy@163.comLiangxing WangDepartment of Respiratory Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, People’s Republic of ChinaEmail 38805@163.comPurpose: The resistance of N. gonorrhoeae to antimicrobial agents has been increasing year by year due to the overuse of antibiotics. The primary aims of the present study were to investigate the molecular characteristics of the clinical isolates of Neisseria gonorrhoeae and the resistance to azithromycin in a Chinese tertiary hospital.Methods: From January 2014 to May 2017, a total of 55 clinical isolates of N. gonorrhoeae were collected. Genes associated with azithromycin resistance (AZM-R), including mutations in 23S rRNA alleles, the mtrR promoter and coding regions, and rplD and rplV were evaluated by PCR and DNA sequencing. All clinical isolates were subjected to N. gonorrhoeae multiantigen sequence typing (NG-MAST), while the AZM-R isolates were further characterized by multilocus sequence typing (MLST).Results: The AZM-R rate in this study was 23.64% (13/55), and a single (A)-nucleotide deletion mutation in the mtrR promoter region, a G45D mutation in the mtrR coding region, a point mutation in rplD, and an A2047G mutation in 23S rRNA alleles were detected in 13, 4, 3 and 4 isolates, respectively; no mutations were found in rplV. There was no significant difference in the mtrR coding region mutation rate between the azithromycin-sensitive and AZM-R groups (P > 0.05); however, there was a significant difference in the mutation rate of the mtrR promoter region (P < 0.05). Among the 55 isolates studied, 43 distinct NG-MAST were determined, while the AZM-R isolates were allocated into 10 distinct MLST/NG-MAST combinations. All three isolates with high-level AZM-R belonged to the sequence types (STs) NG-MAST ST1866 and MLST ST10899.Conclusion: N. gonorrhoeae clinical isolates from Wenzhou, eastern China, showed considerable genetic diversity. Measures should be implemented to monitor the spread of the NG-MAST ST1866 and MLST ST10899 N. gonorrhoeae clones, which exhibit high-level AZM-R in eastern China.Keywords: Neisseria gonorrhoeae, azithromycin, antimicrobial resistance, NG-MAST, MLST

Published
2019

75. Genomic Analysis Of A KPC-2-Producing Klebsiella Pneumoniae ST11 Outbreak From A Teaching Hospital In Shandong Province, China

Author

Chi X, Hu G, Xu H, Li X, Xiao T, Zhou Y, Xia H, Zou H, Han H, Zheng B, and Gao H

Subjects
Klesiella pneumoniae, ST11, whole-genome sequencing, SNP, outbreak, IncFIIK2, Infectious and parasitic diseases, RC109-216
Abstract

Xiaohui Chi,1,2,* Guangchun Hu,3,* Hao Xu,2 Xiucun Li,4 Tingting Xiao,2 Yanzi Zhou,2 Huiyu Xia,1 Huiyun Zou,1 Hui Han,4 Beiwen Zheng,2 Haiyan Gao,4 Xuewen Li1 1Department of Environment and Health, School of Public Health, Shandong University, Jinan 250012, People’s Republic of China; 2Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Disease, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 3Division of Bacteria Diseases, Jinan Municipal Center for Disease Control and Prevention, Jinan, People’s Republic of China; 4Department of Infection Control, Qilu Hospital of Shandong University, Jinan 250012, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xuewen LiDepartment of Environment and Health, School of Public Health, Shandong University, Jinan 250012, People’s Republic of ChinaEmail lxw@sdu.edu.cnHaiyan GaoDepartment of Infection Control, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan 250012, People’s Republic of ChinaEmail 565272040@qq.comPurpose: Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae bacteria causes nosocomial infections worldwide. However, KPC-producing K. pneumoniae outbreak has never been reported in Shandong Province, China. The purpose of our study was to elucidate the epidemiological and drug resistance mechanisms of KPC-producing K. pneumoniae strains collected from a large teaching hospital in Shandong during the outbreak. Moreover, we attempted to characterize the genetic environment and phylogenetic analysis of blaKPC-2 in outbreak isolates.Methods: We monitored a 64-day outbreak of infection in a general hospital in Shandong Province, and the bacteria causing the infection were all ST11-type K. pneumoniae. The genotype correlation of KPC-producing K. pneumoniae isolates was assessed by whole-genome sequencing (WGS) phylogenetic analysis. Subsequent studies included antibiotic susceptibility testing, multilocus sequence typing (MLST) and S1-pulsed-field gel electrophoresis (S1-PFGE), Southern blot hybridization.Results: From February 1, 2018 to April 5, 2018, 14 KPC-producing K. pneumoniae isolates from different wards were collected. All 14 isolates were resistant to carbapenems and carried the extended-spectrum β-lactamase (ESBL) gene as well as fosA, and sul genes. Whole-genome analysis showed that all 14 the outbreak isolates were all ST11 type. The blaKPC-2 carrying plasmids were all belong to IncFIIK2 type, and the size ranged from 94 kb to 368 kb.Conclusion: As far as we know, this report first describes the genomics characterization of KPC-2-producing K. pneumoniae outbreak isolates from Shandong Province, China. In our study, these isolates appeared to be cloned, and ST11 K. pneumoniae was the major clone caused the outbreak. Therefore, routine surveillance of such strains in this region is urgently warranted.Keywords: Klebsiella pneumoniae, ST11, whole-genome sequencing, SNP, outbreak, IncFIIK2

Published
2019

76. Fabrication of KR-12 peptide-containing hyaluronic acid immobilized fibrous eggshell membrane effectively kills multi-drug-resistant bacteria, promotes angiogenesis and accelerates re-epithelialization

Author

Liu M, Liu T, Zhang X, Jian Z, Xia H, Yang J, Hu X, Xing M, Luo G, and Wu J

Subjects
Antimicrobial peptides, hyaluronic acid, fibrous eggshell membrane, antibacterial activity, angiogenesis, re-epithelialization, Medicine (General), R5-920
Abstract

Menglong Liu,1 Tengfei Liu,1 Xiaorong Zhang,1 Zhiwen Jian,2 Hesheng Xia,2 Jiacai Yang,1 Xiaohong Hu,1 Malcolm Xing,1,3 Gaoxing Luo,1 Jun Wu1,41Institute of Burn Research, State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, People’s Republic of China; 2State Key Laboratory of Polymer Materials Engineering, Polymer Research Institute of Sichuan University, Chengdu, 610065, People’s Republic of China; 3Department of Mechanical Engineering, University of Manitoba, Winnipeg, MB R3T 2N2, Canada; 4Department of Burns, the First Affiliated Hospital, SunYat-Sen University, Guangzhou 510080, People’s Republic of ChinaBackground: Designing a wound dressing that effectively prevents multi-drug-resistant bacterial infection and promotes angiogenesis and re-epithelialization is of great significance for wound management.Methods and results: In this study, a biocompatible composite membrane comprising biomimetic polydopamine-modified eggshell membrane nano/microfibres coated with KR-12 antimicrobial peptide and hyaluronic acid (HA) was developed in an eco-friendly manner. The physicochemical properties of the composite membrane were thoroughly characterized, and the results showed that the surface hydrophilicity and water absorption ability of the composite membrane were improved after the successive conjugation of the HA and the KR-12 peptide. Furthermore, the in vitrobiological results revealed that the composite membrane had excellent antibacterial activity against Gram-positive Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA) and Gram-negative Escherichia coli, and it could prevent MRSA biofilm formation on its surface. Additionally, it promoted the proliferation of keratinocytes and human umbilical vein endothelial cells and increased the secretion of VEGF. Finally, an in vivo animal study indicated that the composite membrane could promote wound healing via accelerating angiogenesis and re-epithelialization, which were demonstrated by the enhanced expression of angiogenetic markers (CD31 and VEGF) and keratinocyte proliferation marker (PCNA), respectively.Conclusion: These results indicated that the composite membrane is a potential candidate of wound dressingsKeywords: antimicrobial peptides, hyaluronic acid, fibrous eggshell membrane, antibacterial activity, angiogenesis, re-epithelialization

Published
2019

77. Turbulence-condensate interaction in two dimensions

Author

Xia, H., Punzmann, H., Falkovich, G., and Shats, M. G.

Subjects
Physics - Fluid Dynamics, Physics - Atmospheric and Oceanic Physics
Abstract

We present experimental results on turbulence generated in thin fluid layers in the presence of a large-scale coherent flow, or a spectral condensate. It is shown that the condensate modifies the third-order velocity moment in a much wider interval of scales than the second one. The modification may include the change of sign of the third moment in the inverse cascade. This observation may help resolve a controversy on the energy flux in mesoscale atmospheric turbulence (10-500 km): to recover a correct energy flux from the third velocity moment one needs first to subtract the coherent flow. We find that the condensate also increases the velocity flatness., Comment: 4 pages, 4 figures

Published
2008
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78. What drives mesoscale atmospheric turbulence?

Author

Xia, H., Punzmann, H., Falkovich, G., and Shats, M.

Subjects
Physics - Fluid Dynamics, Physics - Atmospheric and Oceanic Physics
Abstract

Measurements of atmospheric winds in the mesoscale range (10-500 km) reveal remarkably universal spectra with the $k^{-5/3}$ power law. Despite initial expectations of the inverse energy cascade, as in two-dimensional (2D) turbulence, measurements of the third velocity moment in atmosphere, suggested a direct energy cascade. Here we propose a possible solution to this controversy by accounting for the presence of a large-scale coherent flow, or a spectral condensate. We present new experimental laboratory data and show that the presence of a large-scale shear flow modifies the third-order velocity moment in spectrally condensed 2D turbulence, making it, in some conditions, similar to that observed in the atmosphere., Comment: 4 pages, 4 figures

Published
2008

79. Strong ExB shear flows in the pedestal region in H-mode plasma

Author

Xia, H., Shats, M. G., and Punzmann, H.

Subjects
Physics - Plasma Physics
Abstract

We report the first experimental observation of stationary zonal flows in the pedestal region of the H-mode plasma in the H-1 toroidal heliac. Strong peaks in E_r shear mark the top and foot of the density pedestal. Strong m=n=0 low-frequency (f < 0.6 kHz) zonal flows are observed in regions of increased E_r, suggesting substantial contribution of zonal flows to the spatial modulation of E_r radial profiles. Radial localization of zonal flows is correlated with a region of zero magnetic shear and low-order (7/5) rational surfaces., Comment: 4 pages, 5 figures

Published
2006
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82. Self-organization in turbulence as a route to order in plasma and fluids

Author

Shats, M. G., Xia, H., and Punzmann, H.

Subjects
Physics - Plasma Physics, Physics - Fluid Dynamics
Abstract

Transitions from turbulence to order are studied experimentally in thin fluid layers and magnetically confined toroidal plasma. It is shown that turbulence self-organizes through the mechanism of spectral condensation. The spectral redistribution of the turbulent energy leads to the reduction in the turbulence level, generation of coherent flow, reduction in the particle diffusion and increase in the system's energy. The higher order state is sustained via the nonlocal spectral coupling of the linearly unstable spectral range to the large-scale mean flow. The similarity of self-organization in two-dimensional fluids and low-to-high confinement transitions in plasma suggests the universality of the mechanism., Comment: 5 pages, 4 figures

Published
2004
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83. Study of the Sigma-nucleus potential by the (pi^-,K^+) reaction on medium-to-heavy nuclear targets

Author

Saha, P. K., Noumi, H., Abe, D., Ajimura, S., Aoki, K., Bhang, H. C., Dobashi, K., Endo, T., Fujii, Y., Fukuda, T., Guo, H. C., Hashimoto, O., Hotchi, H., Imai, K., Kim, E. H., Kim, J. H., Kishimoto, T., Krutenkova, A., Maeda, K., Nagae, T., Nakamura, M, Outa, H., Saito, T., Sakaguchi, A., Sato, Y., Sawafta, R., Sekimoto, M., Shimizu, Y., Takahashi, T., Tamura, H., Tang, L., Tanida, K., Watanabe, T., Xia, H. H., Zhou, S. H., Zhu, X. F., and Zhu, L. H.

Subjects
Nuclear Experiment
Abstract

In order to study the Sigma-nucleus optical potential, we measured inclusive (pi^-,K^+) spectra on medium-to-heavy nuclear targets: CH_2, Si, Ni, In and Bi. The CH_2 target was used to calibrate the excitation energy scale by using the elementary process p + pi^- -> K^+ + Sigma^-, where the C spectrum was also extracted. The calibration was done with +-0.1 MeV precision. The angular distribution of the elementary cross section was measured, and agreed well with the previous bubble chamber data, but with better statistics, and the magnitudes of the cross sections of the measured inclusive (pi^-,K^+) spectra were also well calibrated. All of the inclusive spectra were found to be similar in shape at a region near to the Sigma^- binding energy threshold, showing a weak mass-number dependence on the magnitude of the cross section. The measured spectra were compared with a theoretical calculation performed within the framework of the Distorted Wave Impulse Approximation (DWIA). It has been demonstrated that a strongly repulsive \sig-nucleus potential with a non-zero size of the imaginary part is required to reproduce the shape of the measured spectra., Comment: 21 pages, 24 figures, submitted to PRC

Published
2004
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85. Application of fluorescein sodium in breast cancer brain-metastasis surgery

Author

Xiao S, Zhang J, Zhu Z, Li Y, Zhong W, Chen J, Pan Z, and Xia H

Subjects
fluorescein sodium, breast cancer brain metastasis, fluorescence-guided surgery, resection rate, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Shi-yin Xiao,1 Ji Zhang,2,* Zheng-quan Zhu,3,* You-ping Li,4,* Wei-ying Zhong,5 Jian-bin Chen,6 Zhen-yu Pan,7 Hai-chen Xia3 1Department of Neurosurgery, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China; 2Department of Neurosurgery, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China; 3Department of Neurosurgery, Tumor Hospital Affiliated of Xinjiang Medical University, Xinshi District, Urumqi, Xinjiang 830011, China; 4Department of Neurosurgery, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330046, China; 5Department of Neurosurgery, Qilu Hospital, Shandong University, Jinan 250012, China; 6Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; 7Department of Radiation-Oncology, First Hospital of Jilin University, Changchun 130021, China *These authors contributed equally to this work Objective: Surgical resection serves an important role in the multidisciplinary treatment of cerebral metastases (CMs). Conventional white-light, microsurgical, and circumferential stripping of CMs is standard neurosurgical procedure, but is associated with a high recurrence rate. Based on this outcome, there is an urgent need for a new surgical strategy, such as fluorescence-guided resection, for CMs, in order to achieve total removal. Methods: A retrospective study was carried out in 38 patients clinically and pathologically diagnosed with breast cancer brain metastasis at three medical centers from May 2012 to June 2016. The study comprised group 1 (fluorescein-guided surgery) and group 2 (standard microsurgery). In group 1, 5 mg/kg of fluorescein sodium was injected intravenously after an allergy test and before general anesthesia for 17 patients. A yellow 560 filter was employed for microsurgical tumor resection. Group 2 consisted of 21 patients for whom fluorescein was not administered. Results: Surgical outcomes were assessed concerning the extent of resection and Karnofsky performance status. Gross total resection was achieved in these patients, with high fluorescence markedly enhancing tumor visibility. The extent of resection had a powerful influence on performance status. Overall survival after CM was 24.1 months in patients given fluorescein and was 22.8 months in the nonfluorescein group. Conclusion: Fluorescein-guided surgery is a simple, safe, and practical method to resect breast cancer brain metastasis, and leads to a higher proportion of resection compared to common microsurgery. This offers a tremendous advantage when navigating a tiny tumor, and improves the quality of life of patients with CM. Keywords: fluorescein sodium, breast cancer brain metastasis, fluorescence-guided surgery, extent of resection, KPS

Published
2018

88. Experimental progress on zonal flow physics in toroidal plasmas

Author

Fujisawa, A, Ido, T, Shimizu, A, Okamura, S, Matsuoka, K, Iguchi, H, Hamada, Y, Nakano, H, Ohshima, S, Itoh, K, Hoshino, K, Shinohara, K, Miura, Y, Nagashima, Y, Itoh, S-I, Shats, M, Xia, H, Dong, JQ, Yan, LW, Zhao, KJ, Conway, GD, Stroth, U, Melnikov, AV, Eliseev, LG, Lysenko, SE, Perfilov, SV, Hidalgo, C, Tynan, GR, Holland, C, Diamond, PH, McKee, GR, Fonck, RJ, Gupta, DK, and Schoch, PM

Subjects
Atomic, Molecular, Nuclear, Particle and Plasma Physics, Fluids & Plasmas
Abstract

The present status of experiments on zonal flows in magnetic confinement experiments is examined. The innovative use of traditional and modern diagnostics has revealed unambiguously the existence of zonal flows, their spatio-temporal characteristics, their relationship to turbulence and their effects on confinement. In particular, a number of observations have been accumulated on the oscillatory branch of zonal flows, named geodesic acoustic modes, suggesting the necessity for theories to give their proper description. In addition to these basic properties of zonal flows, several new methods have elucidated the processes of zonal flow generation from turbulence. Further investigation of the relationship between zonal flows and confinement is strongly encouraged as cross-device activity including low temperature, toroidal and linear devices. © 2007 IAEA.

Published
2007

89. Global multi-stakeholder endorsement of the MAFLD definition

Author

Mendez-Sanchez, N, Bugianesi, E, Gish, R, Lammert, F, Tilg, H, Nguyen, M, Sarin, S, Fabrellas, N, Zelber-Sagi, S, Fan, J, Shiha, G, Targher, G, Zheng, M, Chan, W, Vinker, S, Kawaguchi, T, Castera, L, Yilmaz, Y, Korenjak, M, Spearman, C, Ungan, M, Palmer, M, El-Shabrawi, M, Gruss, H, Dufour, J, Dhawan, A, Wedemeyer, H, George, J, Valenti, L, Fouad, Y, Romero-Gomez, M, Eslam, M, Abate, M, Abbas, B, Abbassy, A, Abd El Ghany, W, Abd Elkhalek, A, Abd ElMajeed, E, Abdalgaber, M, Abdallah, M, Abdallah, N, Abdelaleem, S, Abdelghani, Y, Abdelghany, W, Abdelhalim, S, Abdelhamid, W, Abdelhamid, N, Abdelkader, N, Abdelkreem, E, Abdelmohsen, A, Abdelrahman, A, Abd-elsalam, S, Abdeltawab, D, Abduh, A, Abdulhakam, N, Abdulla, M, Abedpoor, N, Abenavoli, L, Aberg, F, Ablack, O, Abo elftouh, M, Abo-Amer, Y, Aboubkr, A, Aboud, A, Abouelnaga, A, Aboufarrag, G, Aboutaleb, A, Abundis, L, Adali, G, Adames, E, Adams, L, Adda, D, Adel, N, Adel Sayed, M, Afaa, T, Afredj, N, Aghayeva, G, Aghemo, A, Aguilar-Salinas, C, Ahlenstiel, G, Ahmady, W, Ahmed, W, Ahmed, A, Ahmed, S, Ahmed, H, Ahmed, R, Aigner, E, Akarsu, M, Akroush, M, Akyuz, U, Al Mahtab, M, Al Qadiri, T, Al Rawahi, Y, AL rubaee, R, Al Saffar, M, Alam, S, Al-Ani, Z, Albillos, A, Alboraie, M, Al-Busafi, S, Al-Emam, M, Alharthi, J, Ali, K, Ali, B, Ali, M, Ali, R, Alisi, A, AL-Khafaji, A, Alkhatry, M, Aller, R, Almansoury, Y, Al-Naamani, K, Alnakeeb, A, Alonso, A, Alqahtani, S, Alrabadi, L, Alswat, K, Altaher, M, Altamimi, T, Altamirano, J, Alvares-da-Silva, M, Aly, E, Alzahaby, A, Alzamzamy, A, Amano, K, Amer, M, Amin, M, Amin, S, Amir, A, Ampuero, J, Anas, N, Andreone, P, Andriamandimby, S, Anees, M, Angela, P, Antonios, M, Arafat, W, Araya, J, Armendariz-Borunda, J, Armstrong, M, Ashktorab, H, Aspichueta, P, Assal, F, Atef, M, Attia, D, Atwa, H, Awad, R, Awad, M, Awny, S, Awolowo, O, Awuku, Y, Ayada, I, Aye, T, Ayman, S, Ayman, H, Ayoub, H, Azmy, H, Babaran, R, Badreldin, O, Badry, A, Bahcecioglu, I, Bahour, A, Bai, J, Balaban, Y, Balasubramanyam, M, Bamakhrama, K, Banales, J, Bangaru, B, Bao, J, Barahona, J, Barakat, S, Barbalho, S, Barbra, B, Barranco, B, Barrera, F, Baumann, U, Bazeed, S, Bech, E, Benayad, A, Benesic, A, Bernstein, D, Bessone, F, Birney, S, Bisseye, C, Blake, M, Bobat, B, Bonfrate, L, Bordin, D, Bosques-Padilla, F, Boursier, J, Boushab, B, Bowen, D, Bravo, P, Brennan, P, Bright, B, Broekaert, I, Buque, X, Burgos-Santamaria, D, Burman, J, Busetto, L, Byrne, C, Cabral-Prodigalidad, P, Cabrera-Alvarez, G, Cai, W, Cainelli, F, Caliskan, A, Canbay, A, Cano-Contreras, A, Cao, H, Cao, Z, Carrion, A, Carubbi, F, Casanovas, T, Castellanos Fernandez, M, Chai, J, Chan, S, Charatcharoenwitthaya, P, Chavez-Tapia, N, Chayama, K, Chen, J, Chen, L, Chen, Z, Chen, H, Chen, S, Chen, Q, Chen, Y, Chen, G, Chen, E, Chen, F, Chen, P, Cheng, R, Cheng, W, Chieh, J, Chokr, I, Cholongitas, E, Choudhury, A, Chowdhury, A, Chukwudike, E, Ciardullo, S, Clayton, M, Clement, K, Cloa, M, Coccia, C, Collazos, C, Colombo, M, Cosar, A, Cotrim, H, Couillerot, J, Coulibaly, A, Crespo, G, Crespo, J, Cruells, M, Cua, I, Dabbous, H, Dalekos, G, D'Alia, P, Dan, L, Dao, V, Darwish, M, Datz, C, Davalos-Moscol, M, Dawoud, H, de Careaga, B, de Knegt, R, de Ledinghen, V, de Silva, J, Debzi, N, Decraecker, M, Del Pozo, E, Delgado, T, Delgado-Blanco, M, Dembinski, L, Depina, A, Derbala, M, Desalegn, H, Desbois-Mouthon, C, Desoky, M, Dev, A, Di Ciaula, A, Diago, M, Diallo, I, Diaz, L, Dirchwolf, M, Dongiovanni, P, Dorofeyev, A, Dou, X, Douglas, M, Doulberis, M, Dovia, C, Doyle, A, Dragojevic, I, Drenth, J, Duan, X, Dulskas, A, Dumitrascu, D, Duncan, O, Dusabejambo, V, Dwawhi, R, Eiketsu, S, El Amrousy, D, El Deeb, A, El Deriny, G, El Din, H, El Kamshishy, S, El Kassas, M, El Raziky, M, Elagamy, O, Elakel, W, Elalfy, D, Elaraby, H, Elawady, H, Elbadawy, R, Eldash, H, Eldefrawy, M, Elecharri, C, Elfaramawy, A, Elfatih, M, Elfiky, M, Elgamsy, M, Elgendy, M, El-Guindi, M, Elhussieny, N, Eliwa, A, Elkabbany, Z, El-Khayat, H, El-Koofy, N, Elmetwalli, A, Elrabat, A, El-Raey, F, Elrashdy, F, Elsahhar, M, Elsaid, E, Elsayed, S, Elsayed, H, Elsayed, A, El-Serafy, M, Elsharkawy, A, Elsheemy, R, Elshemy, E, Elsherbini, S, Eltoukhy, N, Elwakil, R, Emad, O, Emad, S, Embabi, M, Ergenc, I, Ermolova, T, Esmat, G, Esmat, D, Estupinan, E, Ettair, S, Eugen, T, Ezz-Eldin, M, Falcon, L, Fan, Y, Fandari, S, Farag, M, Farahat, T, Fares, E, Fares, M, Fassio, E, Fathy, H, Fathy, D, Fathy, W, Fayed, S, Feng, D, Feng, G, Fernandez-Bermejo, M, Ferreira, C, Ferrer, J, Forbes, A, Fouad, R, Fouad, H, Frisch, T, Fujii, H, Fukunaga, S, Fukunishi, S, Fulya, H, Furuhashi, M, Gaber, Y, Galang, A, Gallardo, J, Galloso, R, Gamal, M, Gamal, R, Gamal, H, Gan, J, Ganbold, A, Gao, X, Garas, G, Garba, T, Garcia-Cortes, M, Garcia-Monzon, C, Garcia-Samaniego, J, Gastaldelli, A, Gatica, M, Gatley, E, Gegeshidze, T, Geng, B, Ghazinyan, H, Ghoneem, S, Giacomelli, L, Giannelli, G, Giannini, E, Giefer, M, Gines, P, Girala, M, Giraudi, P, 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M., Palle S., Pan Z., Pan X. -Y., Pan Q., Papaefthymiou A., Paquissi F. C., Par G., Parkash A., Payawal D., Peltekian K. M., Peng X., Peng L., Peng Y., Pengoria R., Perez M., Perez J. L., Perez N. M., Persico M., Pessoa M. G., Petta S., Philip M., Plaz Torres M. C., Polavarapu N., Poniachik J., Portincasa P., Pu C., Purnak T., Purwanto E., Qi X., Qian Z., Qiang Z., Qiao Z., Qiao L., Queiroz A., Rabiee A., Radwan M., Rahetilahy A. M., Ramadan Y., Ramadan D., Ramli A. S., Ramm G. A., Ran A., Rankovic I., RAO H., Raouf S., Ray S., Reau N., Refaat A., Reiberger T., Remes-Troche J. M., Reyes E. C., Richardson B., Ridruejo E., Riestra Jimenez S., Rizk I., Roberts S., Roblero J. P., Robles J. A. P., Rockey D., Rodriguez M., Rodriguez Hernandez H., Roman E., Romeiro F. G., Romeo S., Rosales-Zabal J. M., Roshdi G. R., Rosso N., Ruf A., Ruiz P. C., Runes N. R., Ruzzenente A., Ryan M., Saad A., Sabbagh E. B., Sabbah M., Saber S., Sabrey R., Sabry R., Saeed M. A., Said D., Said E. M., Sakr M. 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M., Xia H., Xiao J., Xiao X., Xiaofeng W., Xiong W., Xu L., Xu J., Xu W., Xu J. -H., Xu K., Xu Y., Xu S. -H., Xu M., Xu A., Xu C., Yan H., Yang J., Yang R. -X., Yang Y., Yang Q., Yang N., Yao J., Yara J., Yaras S., Yilmaz N., Younes R., younes H., Young S., Youssef F., Yu Y., Yu M. -L., Yuan J., Yue Z., Yuen M. -F., Yun W., Yurukova N., Zakaria S., Zaky S., Zaldastanishvili M., Zapata R., Zare N., Zerem E., Zeriban N., Zeshuai X., Zhang H., Zhang X., Zhang Y., Zhang W. -H., Zhang Y. -P., Zhang Z. -Q., Zhao J., Zhao R. -R., Zhao H., Zheng C., Zheng Y., Zheng R., Zheng T. -L., Zheng K., Zhou X. Q., Zhou Y., Zhou Y. -J., Zhou H., Zhou L., Zhu L. D., Zhu Y. F., Zhu Y., Zhu P. -W., Ziada E., Ziring D., Ziyi L., Zou S., Zou Z., Zou H., and Zuart Ruiz R.

Published
2022

91. The expression profiles of miRNA–mRNA of early response in genetically improved farmed tilapia (Oreochromis niloticus) liver by acute heat stress

Author

Jun Qiang, Wen J. Bao, Fan Y. Tao, Jie He, Xia H. Li, Pao Xu, and Lan Y. Sun

Subjects
Medicine, Science
Abstract

Abstract Genetically improved farmed tilapia (GIFT, Oreochromis niloticus) are commercially important fish that are cultured in China. GIFT are highly susceptible to diseases when exposed to high temperatures in summer. Better understanding the GIFT regulatory response to heat stress will not only help in determining the relationship between heat stress signalling pathways and adaption mechanisms, but will also contribute to breeding new high-temperature tolerant strains of GIFT. In this study, we built control (28 °C) and heat-treated (37.5 °C) groups, and extracted RNA from the liver tissues for high-throughput next-generation sequencing to study the miRNA and mRNA expression profiles. We identified 28 differentially expressed (DE) miRNAs and 744 DE mRNAs between the control and heat-treated groups and annotated them using the KEGG database. A total of 38 target genes were predicted for 21 of the DE miRNAs, including 64 negative miRNA–mRNA interactions. We verified 15 DE miRNA–mRNA pairs and 16 other DE mRNAs by quantitative real-time PCR. Important regulatory pathways involved in the early response of GIFT to heat stress included organism system, metabolism, and diseases. Our findings will facilitate the understanding of regulatory pathways affected by acute heat stress, which will help to better prevent heat damage to GIFT.

Published
2017
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96. The interplay of single-particle and collective motions in the low-lying states of $$_\Lambda ^{21}$$ with quadrupole-octupole correlations

Author

Xia, H. J., Wu, X. Y., Mei, H., and Yao, J. M.

Subjects
Nuclear Theory, General Physics and Astronomy, Nuclear Experiment
Abstract

The beyond mean-field approach for low-lying hypernuclear states is extended by mixing the configurations associated with both single-particle and quadrupole-octupole collective excitations within the generator coordinate method based on a covariant density functional theory. The method is demonstrated in the application to the low-lying states of $^{21}_\Lambda$Ne, where the configurations with the $\Lambda$ hyperon occupying the first ($\Lambda_s$) and second ($\Lambda_p$) lowest-energy states are considered. The results indicate that the positive-parity states are dominated by the $\alpha+^{12}$C+$\alpha+\Lambda_s$ structure. In contrast, the low-lying negative-parity states are dominated by a strong admixture of $\alpha+^{16}$O+$\Lambda_s$ structure and $\alpha+^{12}$C+$\alpha+\Lambda_p$ structure due to the inclusion of octupole correlations. As a result, the low-lying negative-parity states become much lower than what is expected from the previous studies without the mixing, and the electric multipole transition strengths are significantly quenched., Comment: 9 pages with 5 figures and 2 tables

Published
2023

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