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6,949 results on '"Wu, Xia"'

51. TARDRL: Task-Aware Reconstruction for Dynamic Representation Learning of fMRI

Author

Zhao, Yunxi, Nie, Dong, Chen, Geng, Wu, Xia, Zhang, Daoqiang, Wen, Xuyun, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Linguraru, Marius George, editor, Dou, Qi, editor, Feragen, Aasa, editor, Giannarou, Stamatia, editor, Glocker, Ben, editor, Lekadir, Karim, editor, and Schnabel, Julia A., editor

Published
2024
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52. Adaptive Augmentation and Neighbor Contrastive Learning for Multi-Behavior Recommendation

Author

Wu, Xia, Wang, Shaoqing, Zhang, Yao, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Zhang, Wenjie, editor, Tung, Anthony, editor, Zheng, Zhonglong, editor, Yang, Zhengyi, editor, Wang, Xiaoyang, editor, and Guo, Hongjie, editor

Published
2024
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53. Tripartite Evolutionary Game of Government-Industry-University in Seasonal-Transportation of Freight Enterprises Under the Background of Carbon-Peaking and Carbon-Neutrality Goals

Author

Jia, Kaiwei, Wu, Xia, Appolloni, Andrea, Series Editor, Caracciolo, Francesco, Series Editor, Ding, Zhuoqi, Series Editor, Gogas, Periklis, Series Editor, Huang, Gordon, Series Editor, Nartea, Gilbert, Series Editor, Ngo, Thanh, Series Editor, Striełkowski, Wadim, Series Editor, Zailani, Suhaiza Hanim Binti Dato Mohamad, editor, Yagapparaj, Kosga, editor, and Zakuan, Norhayati, editor

Published
2024
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57. Spirometric pattern and cardiovascular risk: a prospective study of 0.3 million Chinese never-smokers

Author

Chen, Junshi, Chen, Zhengming, Clarke, Robert, Collins, Rory, Li, Liming, Lv, Jun, Peto, Richard, Walters, Robin, Avery, Daniel, Barnard, Maxim, Bennett, Derrick, Boxall, Ruth, Chan, Ka Hung, Chen, Yiping, Clarke, Charlotte, Clarke, Johnathan, Du, Huaidong, Mohamed, Ahmed Edris, Fry, Hannah, Gilbert, Simon, Im, Pek Kei, Iona, Andri, Kakkoura, Maria, Kartsonaki, Christiana, Kolhe, Kshitij, Lam, Hubert, Lin, Kuang, Liu, James, Mazidi, Mohsen, Millwood, Iona, Morris, Sam, Nie, Qunhua, Pozarickij, Alfred, Rahmati, Maryam, Ryder, Paul, Schmidt, Dan, Stevens, Becky, Turnbull, Iain, Wang, Baihan, Wang, Lin, Wright, Neil, Yang, Ling, Yang, Xiaoming, Yao, Pang, Han, Xiao, Hou, Can, Xia, Qingmei, Liu, Chao, Pei, Pei, Sun, Dianjianyi, Yu, Canqing, Pan, Lang, Pang, Zengchang, Gao, Ruqin, Li, Shanpeng, Duan, Haiping, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Wang, Junzheng, Hou, Wei, Sun, Wei, Yan, Shichun, Cui, Xiaoming, Wang, Chi, Wu, Zhenyuan, Li, Yanjie, Kang, Quan, Luo, Huiming, Ou, Tingting, Zheng, Xiangyang, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Tao, Ran, Yang, Jie, Su, Jian, Liu, Fang, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Lin, Mei, Lu, Zhenzhen, Zhou, Lifang, Xie, Changping, Lan, Jian, Zhu, Tingping, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Qin, Yulu, Wang, Sisi, Wu, Xianping, Zhang, Ningmei, Chen, Xiaofang, Chang, Xiaoyu, Yuan, Mingqiang, Wu, Xia, Jiang, Wei, Liu, Jiaqiu, Sun, Qiang, Chen, Faqing, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Kang, Kai, Feng, Shixian, Tian, Huizi, Fan, Lei, Li, XiaoLin, Sun, Huarong, He, Pan, Zhang, Xukui, Yu, Min, Hu, Ruying, Wang, Hao, Zhang, Xiaoyi, Cao, Yuan, Xie, Kaixu, Chen, Lingli, Shen, Dun, Li, Xiaojun, Jin, Donghui, Yin, Li, Liu, Huilin, Fu, Zhongxi, Xu, Xin, Zhang, Hao, Chen, Jianwei, Peng, Yuan, Zhang, Libo, Qu, Chan, Li, Shuya, Qin, Haiqiang, Wang, Yongjun, Chen, Qiling, Wang, Jihua, Sun, Xiaojia, Wang, Lei, Wang, Xun, Zhang, Liming, Zhou, Shanshan, Chen, Hongyuan, Chen, Li, Gou, Haiyan, Wang, Weizhi, Zhu, Yanmei, Zhu, Yulan, Zhang, Ning, Cheng, Xin, Dong, Qiang, Dong, Yi, Fang, Kun, Mao, Yiting, An, Yu, Chen, Peiling, Chen, Yinghua, Liu, Zhihong, Zhang, Lihua, Chen, Xiaohong, Jv, Naixin, Li, Xiaojiu, Liu, Liyang, Lu, Yun, Xing, Xiaona, You, Shihao, Cheng, Xiaoli, Gua, Chaojun, Jiang, Jinping, Liu, Jingyi, Ma, Shumei, Yang, Xuefeng, Du, Xiaomo, Xu, Jian, Yang, Xuecheng, Zhao, Xiaodi, Hao, Zilong, Liu, Ming, Wang, Deren, Li, Xiaoting, Hui, Lili, Liao, Zhanling, Liu, Feng, Feng, Chunning, Ji, Dejiang, Qu, Fengxia, Yuan, Wenwen, Fu, Xin, Ding, Jing, Du, Peng, Jin, Lirong, Mao, Yueshi, Wang, Xin, Ding, Yinqi, and Hu, Jingcen

Published
2025
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66. Evidence-based guidelines for drug dosing in intravitreal injections in silicone oil-filled eyes: Pharmacokinetics, safety, and optimal dosage

Author

Ferro Desideri, Lorenzo, Sim, Peng Yong, Bernardi, Enrico, Paschon, Karin, Roth, Janice, Fung, Adrian T., Wu, Xia Ni, Chou, Hung-Da, Henderson, Robert, Tsui, Edmund, Berrocal, Maria, Chhablani, Jay, Wykoff, Charles C., Cheung, Chui Ming Gemmy, Querques, Giuseppe, Melo, Gustavo Barreto, Subhi, Yousif, Loewenstein, Anat, Kiilgaard, Jens Folke, Zinkernagel, Martin, and Anguita, Rodrigo

Published
2025
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70. Associations of long-term nitrogen dioxide exposure with a wide spectrum of diseases: a prospective cohort study of 0·5 million Chinese adults

Author

Chen, Junshi, Chen, Zhengming, Clarke, Robert, Collins, Rory, Li, Liming, Lv, Jun, Peto, Richard, Walters, Robin, EdrisMohamed, Ahmed, Pozarickij, Alfred, Iona, Andri, Wang, Baihan, Clarke, Charlotte, Kartsonaki, Christiana, Schmidt, Dan, Avery, Daniel, Bennett, Derrick, Fry, Hannah, Du, Huaidong, Lam, Hubert, Turnbull, Iain, Millwood, Iona, Liu, James, Clarke, Jonathan, Chan, Ka Hung, Kolhe, Kshitij, Lin, Kuang, Wang, Lin, Yang, Ling, Kakkoura, Maria, Rahmati, Maryam, Barnard, Maxim, Mazidi, Mohsen, Wright, Neil, Yao, Pang, Ryder, Paul, Im, Pek Kei, Harish, Prapthi, Nie, Qunhua, Stevens, Rebecca, Boxall, Ruth, Morris, Sam, Gilbert, Simon, Yang, Xiaoming, Chen, Yiping, Han, Xiao, Hou, Can, Xia, Qingmei, Liu, Chao, Pei, Pei, Sun, Dianjianyi, Yu, Canqing, Pan, Lang, Pang, Zengchang, Gao, Ruiqin, Li, Shanpeng, Duan, Haiping, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Wang, Junzheng, Hou, Wei, Sun, Wei, Yan, Shichun, Cui, Xiaoming, Wang, Chi, Wu, Zhenyuan, Li, Yanjie, Kang, Quan, Luo, Huiming, Qu, Tingting, Zheng, Xiangyang, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Tao, Ran, Yang, Jie, Su, Jian, Liu, Fang, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Lin, Mei, Lu, Zhenzhen, Zhou, Lifang, Xie, Changping, Lan, Jian, Zhu, Tingping, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Qin, Yulu, Wang, Sisi, Wu, Xiangping, Zhang, Ningmei, Chen, Xiaofang, Chang, Xiaoyu, Yuan, Mingqiang, Wu, Xia, Jiang, Wei, Liu, Jiaqiu, Sun, Qiang, Chen, Faqing, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Kang, Kai, Feng, Shixian, Tian, Huizi, Fan, Lei, Li, Xiaolin, Sun, Huarong, He, Pan, Zhang, Xukui, Yu, Min, Hu, Ruying, Wang, Hao, Zhang, Xiaoyi, Cao, Yuan, Xie, Kaixu, Chen, Lingli, Shen, Dun, Li, Xiaojun, Jin, Donghui, Yin, Li, Liu, Huilin, Fu, Zhongxi, Xu, Xin, Zhang, Hao, Chen, Jianwei, Peng, Yuan, Zhang, Libo, Qu, Chan, Xia, Xi, Meng, Xia, Liu, Cong, Guo, Yi, Li, Xinyue, Niu, Yue, Lam, Kin Bong Hubert, Gao, Ruqin, Wu, Shaowei, and Kan, Haidong

Published
2024
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94. Intrarenal 1-methoxypyrene, an aryl hydrocarbon receptor agonist, mediates progressive tubulointerstitial fibrosis in mice.

Author

Cao, Gang, Miao, Hua, Wang, Yan-Ni, Chen, Dan-Qian, Wu, Xia-Qing, Chen, Lin, Guo, Yan, Zou, Liang, Li, Ping, Zhao, Ying-Yong, and Vaziri, Nosratola

Subjects
Semen plantaginis, aryl hydrocarbon receptor, epithelial-mesenchymal transition, macrophage-myofibroblast transition, metabolomics, tubulointerstitial fibrosis, Mice, Animals, Receptors, Aryl Hydrocarbon, Fibrosis, Kidney Diseases, Ureteral Obstruction, RNA, Messenger
Abstract

Recent studies have shown that endogenous metabolites act via aryl hydrocarbon receptor (AhR) signalling pathway in tubulointerstitial fibrosis (TIF) pathogenesis. However, the mechanisms underlying endogenous metabolite-mediated AhR activation are poorly characterised. In this study, we conducted untargeted metabolomics analysis to identify the significantly altered intrarenal metabolites in a mouse model of unilateral ureteral obstruction (UUO). We found that the levels of the metabolite 1-methoxypyrene (MP) and the mRNA expression of AhR and its target genes CYP1A1, CYP1A2, CYP1B1 and COX-2 were progressively increased in the obstructed kidney at Weeks 1, 2 and 3. Furthermore, these changes were positively correlated with progressive TIF in UUO mice. In NRK-52E, RAW 264.7 and NRK-49F cells, MP dose-dependently upregulated the mRNA expression of AhR and its four target genes and the protein expression of nuclear AhR, accompanied by the upregulated protein expression of collagen I, α-SMA and fibronectin, as well as downregulated E-cadherin expression. Consistently, oral administration of MP in mice progressively enhanced AhR activity and upregulated profibrotic protein expression in the kidneys; these effects were partially inhibited by AhR knockdown in MP-treated mice and cell lines. In addition, we screened and identified erythro-guaiacylglycerol-β-ferulic acid ether (GFA), which was isolated from Semen plantaginis, as a new AhR antagonist. GFA significantly attenuated TIF in MP-treated NRK-52E cells and mice by partially antagonising AhR activity. Our results suggest that MP activates AhR signalling, thus mediating TIF through epithelial-mesenchymal transition and macrophage-myofibroblast transition. MP is a crucial metabolite that contributes to TIF via AhR signalling pathway.

Published
2022

100. One-size-fits-all versus risk-category-based screening interval strategies for cardiovascular disease prevention in Chinese adults: a prospective cohort study

Author

Chen, Junshi, Chen, Zhengming, Clarke, Robert, Collins, Rory, Li, Liming, Lv, Jun, Peto, Richard, Walters, Robin, Avery, Daniel, Barnard, Maxim, Bennett, Derrick, Belbasis, Lazaros, Boxall, Ruth, Chan, Ka Hung, Chen, Yiping, Clarke, Charlotte, Clarke, Johnathan, Du, Huaidong, Mohamed, Ahmed Edris, Fry, Hannah, Gilbert, Simon, Im, Pek Kei, Iona, Andri, Kakkoura, Maria, Kartsonaki, Christiana, Lam, Hubert, Lin, Kuang, Liu, James, Mazidi, Mohsen, Millwood, Iona, Morris, Sam, Nie, Qunhua, Pozarickij, Alfred, Rahmati, Maryanm, Ryder, Paul, Said, Saredo, Schmidt, Dan, Stevens, Becky, Turnbull, Iain, Wang, Baihan, Wang, Lin, Wright, Neil, Yang, Ling, Yang, Xiaoming, Yao, Pang, Han, Xiao, Hou, Can, Xia, Qingmei, Liu, Chao, Pei, Pei, Sun, Dianjianyi, Yu, Canqing, Pan, Lang, Pang, Zengchang, Gao, Ruqin, Li, Shanpeng, Duan, Haiping, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Wang, Junzheng, Hou, Wei, Sun, Wei, Yan, Shichun, Cui, Xiaoming, Wang, Chi, Wu, Zhenyuan, Li, Yanjie, Kang, Quan, Luo, Huiming, Ou, Tingting, Zheng, Xiangyang, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Tao, Ran, Yang, Jie, Fang Liu, Jian Su., Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Lin, Mei, Lu, Zhenzhen, Zhou, Lifang, Xie, Changping, Lan, Jian, Zhu, Tingping, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Qin, Yulu, Wang, Sisi, Wu, Xianping, Zhang, Ningmei, Chen, Xiaofang, Chang, Xiaoyu, Yuan, Mingqiang, Wu, Xia, Jiang, Wei, Liu, Jiaqiu, Sun, Qiang, Chen, Faqing, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Kang, Kai, Feng, Shixian, Tian, Huizi, Fan, Lei, Li, XiaoLin, Sun, Huarong, He, Pan, Zhang, Xukui, Yu, Min, Hu, Ruying, Wang, Hao, Zhang, Xiaoyi, Cao, Yuan, Xie, Kaixu, Chen, Lingli, Shen, Dun, Li, Xiaojun, Jin, Donghui, Yin, Li, Liu, Huilin, Fu, Zhongxi, Xu, Xin, Zhang, Hao, Chen, Jianwei, Peng, Yuan, Zhang, Libo, Qu, Chan, Sun, Zhijia, Ma, Yu, and Pang, Yuanjie

Published
2024
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