3,801 results on '"Wu, E."'
Search Results
52. Experimental and computational evaluation of a sodium-rich anti-perovskite for solid state electrolytes
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Nguyen, H, Hy, S, Wu, E, Deng, Z, Samiee, M, Yersak, T, Luo, J, Ong, SP, and Meng, YS
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Macromolecular and Materials Chemistry ,Physical Chemistry (incl. Structural) ,Materials Engineering ,Energy - Abstract
In this study we experimentally investigated the effects of two processing techniques on the sodium-rich anti-perovskite, Na3OBr; namely, conventional cold pressing (CP) and spark plasma sintering (SPS). We demonstrated that the electrolyte can be synthesized via a single-step solid state reaction. We compared the CP and SPS processed samples using XRD, SEM, and EIS. From these analyses it was found that SPS reduced Na3OBr's interfacial impedance by three orders of magnitude, which translated into an increase in the overall ionic conductivity and a reduction in the activation energy, from 1.142 eV to 0.837 eV. DFT was used to probe the mechanisms for ionic transport in Na-rich Na3OBr. The formation energies of ion diffusion-facilitating defects in Na3OBr were found to be much higher compared to the lithium-rich anti-perovskites (LiRAP), which can explain the difference in overall ionic conductivity between the two.
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- 2016
53. Polysaccharides from Dendrobium officinale improve obesity‐induced insulin resistance through the gut microbiota and the SOCS3‐mediated insulin receptor substrate‐1 signaling pathway
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Jiang, Wei, primary, Tan, Jin, additional, Zhang, Jiacheng, additional, Deng, Xin, additional, He, Xinyue, additional, Zhang, Jin, additional, Liu, Tong, additional, Sun, Rong, additional, Sun, Mengxun, additional, Chen, Kuo, additional, Xu, Tingjia, additional, Yan, Yuling, additional, Moazzami, Ali, additional, Wu, E‐Jiao, additional, Zhan, Jiasui, additional, and Hu, Binhong, additional
- Published
- 2023
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54. ASCEND-Eye
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Sammons, Emily L., primary, Buck, Georgina, additional, Bowman, Louise J., additional, Stevens, William M., additional, Hammami, Imen, additional, Parish, Sarah, additional, Armitage, Jane, additional, Sammons, Emily, additional, Bowman, Louise, additional, Stevens, William, additional, Collins, R., additional, Armitage, J., additional, Barton, J., additional, Simpson, D., additional, Adler, A., additional, Aung, T., additional, Baigent, C., additional, Bodansky, H.J., additional, Farmer, A., additional, Haynes, R., additional, McPherson, R., additional, Mafham, M., additional, Neil, H.A.W., additional, Samani, N., additional, Sleight, P., additional, Weissberg, P., additional, Sandercock, P., additional, Gerstein, H., additional, Gray, R., additional, Hennekens, C., additional, Fletcher, L., additional, Murphy, K., additional, Hurley, S., additional, Lee, R., additional, Pickworth, S., additional, Willett, M., additional, Wincott, M., additional, Lay, M., additional, Buck, G., additional, Murawska, A., additional, Stevens, W., additional, Wallendszus, K., additional, Young, A., additional, Hammami, I., additional, Brown, G., additional, Latham-Mollart, J., additional, Brewer, A., additional, Scanlon, P., additional, Patel, P., additional, Olson, M., additional, Kay, J., additional, Banerjee, S., additional, Evans, L., additional, Davies, A., additional, Griffiths, M., additional, Clayton, H., additional, Kirby, P., additional, Pennington, M., additional, Clarke, D., additional, Anslow, J., additional, Hallam, A., additional, Witts, J., additional, Egan, S., additional, Wharton, A., additional, Sachdev, A., additional, Derbyshire, A., additional, Williamson, E., additional, Hepplestone, K., additional, Mithra, S., additional, Oliver, S., additional, Wiatrak-Olszewska, P., additional, Gazis, T., additional, Alvey, K., additional, Wu, E., additional, Cook, H., additional, Gregory, N., additional, Parkinson, P., additional, Anderson, J., additional, Bolter, L., additional, Maharajan, P., additional, McFee, R., additional, Allsop, L., additional, Sowter, D., additional, Hodgson, D., additional, Thow, J., additional, Featonby, J., additional, Furnival, R., additional, Lipinski, H., additional, Benjamin, H., additional, McAfee, T., additional, Payne, E., additional, and Still, L., additional
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- 2023
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55. Chandra detection of a new diffuse X-ray component from the globular cluster 47 Tucanae
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Wu, E. M. H., Hui, C. Y., Kong, A. K. H., Tam, P. H. T., Cheng, K. S., and Dogiel, V. A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
In re-analyzing the archival Chandra data of the globular cluster 47 Tucanae, we have detected a new diffuse X-ray emission feature within the half-mass radius of the cluster. The spectrum of the diffuse emission can be described by a power-law model plus a plasma component with photon index $\Gamma\sim1.0$ and plasma temperature $kT\sim0.2$ keV. While the thermal component is apparently uniform, the non-thermal contribution falls off exponentially from the core. The observed properties could possibly be explained in the context of multiple shocks resulted from the collisions among the stellar wind in the cluster and the inverse Compton scattering between the pulsar wind and the relic photons., Comment: 14 pages, 3 figures, 2 tables, Accepted for publication in ApJ Letter
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- 2014
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56. Tunable Fano resonances in heterogenous Al-Ag nanorod dimer
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Ci, Xueting, Wu, Botao, Song, Min, Liu, Yan, Chen, Gengxu, Wu, E, and Zeng, Heping
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Physics - Optics - Abstract
We theoretically investigate the plasmonic coupling in heterogenous Al-Ag nanorod dimer. A pronounced Fano dip is found in the extinction spectrum produced by the destructive interference between the bright dipole mode from a short Al nanorod and the dark quadrupole mode from a long Ag nanorod nearby. This Fano resonance can be widely tuned in both wavelength and amplitude by varying the rod dimensions, the separation distance and the local dielectric environment. The Al-Ag heterogeneous nanorod dimer shows a high sensitivity to the surrounding environment with a local surface plasmon resonance figure of merit of 7.0, which enables its promising applications in plasmonic sensing and detection., Comment: 10 pages, 5 figures
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- 2013
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57. Multi-wavelength emissions from the millisecond pulsar binary PSR J1023+0038 during an accretion active state
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Takata, J., Li, K. L., Leung, G. C. K., Kong, A. K. H., Tam, P. H. T., Hui, C. Y., Wu, E. M. H., Xing, Y., Cao, Y., Tang, S., Wang, Z., and Cheng, K. S.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Recent observations strongly suggest that the millisecond pulsar binary PSR J1023+0038 has developed an accretion disk since 2013 June. We present a multi-wavelength analysis of PSR J1023+0038, which reveals that 1) its gamma-rays suddenly brightened within a few days in June/July 2013 and has remained at a high gamma-ray state for several months; 2) both UV and X-ray fluxes have increased by roughly an order of magnitude, and 3) the spectral energy distribution has changed significantly after the gamma-ray sudden flux change. Time variabilities associated with UV and X-rays are on the order of 100-500 seconds and 50-100 seconds, respectively. Our model suggests that a newly formed accretion disk due to the sudden increase of the stellar wind could explain the changes of all these observed features. The increase of UV is emitted from the disk, and a new component in gamma-rays is produced by inverse Compton scattering between the new UV component and pulsar wind. The increase of X-rays results from the enhancement of injection pulsar wind energy into the intra-binary shock due to the increase of the stellar wind. We also predict that the radio pulses may be blocked by the evaporated winds from the disk and the pulsar is still powered by rotation., Comment: 8 pages, 3 figures; accepted for publication in ApJ
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- 2013
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58. Unveiling Tatun volcanic plumbing structure induced by post-collisional extension of Taiwan mountain belt
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Huang, Hsin-Hua, Wu, E.-S., Lin, C.-H., Ko, J. Y.-T., Shih, M.-H., and Koulakov, I.
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- 2021
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59. Distance-Dependent Plasmon-Enhanced Fluorescence of Submonolayer Rhodamine 6G by Gold Nanoparticles
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Bian, Yajie, Liu, Shikang, Zhang, Yuyi, Liu, Yiting, Yang, Xiaoyu, Lou, Shitao, Wu, E., Wu, Botao, Zhang, Xiaolei, and Jin, Qingyuan
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- 2021
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60. O-03: ETAVOPIVAT TREATMENT FOR UP TO 12 WEEKS IN PATIENTS WITH SICKLE CELL DISEASE IS WELL TOLERATED AND IMPROVES RED BLOOD CELL HEALTH
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TELEN M., BROWN R., HAGAR R., IDOWU M., OSUNKWO I., KALFA T., KUYPERS F., GEIB J., SCHROEDER P., WU E., KELLY P., and SARAF S.
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Diseases of the blood and blood-forming organs ,RC633-647.5 - Published
- 2022
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61. Five-Partite Continuous-Variable Quantum State Sharing
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Wu, E.
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- 2020
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62. Steady-State Spin Squeezing Generated in Diamond Nanostructures Coupled to Carbon Nanotubes
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Ma, Yong-Hong, Liu, Xin-Ru, Liu, Jia, Niu, Jin-Yan, Zhang, Yong, Wu, E, and Ding, Quan-Zhen
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- 2020
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63. Preventing Loss of Independence through Exercise (PLIÉ): Qualitative analysis of a clinical trial in older adults with dementia
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Wu, E, Barnes, DE, Ackerman, SL, Lee, J, Chesney, M, and Mehling, WE
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Medical and Health Sciences ,Studies in Human Society ,Psychology and Cognitive Sciences ,Geriatrics - Abstract
Objectives: Preventing Loss of Independence through Exercise (PLIÉ) is a novel, integrative exercise program for individuals with dementia that combines elements of different conventional and complementary exercise modalities (e.g. tai-chi, yoga, Feldenkrais, and dance movement therapy) and focuses on training procedural memory for basic functional movements (e.g., sit-to-stand) while increasing mindful body awareness and facilitating social connection. This study presents analyses of qualitative data collected during a 36-week cross-over pilot clinical trial in 11 individuals.Methods: Qualitative data included exercise instructors written notes, which were prepared after each class and also following biweekly telephone calls with caregivers and monthly home visits; three video-recorded classes; and written summaries prepared by research assistants following pre-and post-intervention quantitative assessments. Data were extracted for each study participant and placed onto a timeline for month of observation. Data were coded and analyzed to identify themes that were confirmed and refined through an iterative, collaborative process by the entire team including a qualitative researcher (SA) and the exercise instructors.Results: Three overarching themes emerged: (1) Functional changes included increasing body awareness, movement memory and functional skill. (2) Emotional changes included greater acceptance of resting, sharing of personal stories and feelings, and positive attitude toward exercise. (3) Social changes included more coherent social interactions and making friends.Conclusions: These qualitative results suggest that the PLIÉ program may be associated with beneficial functional, emotional, and social changes for individuals with mild to moderate dementia. Further study of the PLIÉ program in individuals with dementia is warranted.
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- 2015
64. Preventing Loss of Independence through Exercise (PLIÉ): A pilot clinical trial in older adults with dementia
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Yaffe, Kristine, Chesney, Margaret, Barnes, DE, Mehling, W, Wu, E, Beristianos, M, and Skultety, K
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© 2015, Public Library of Science. All rights reserved.Background: Current dementia medications have small effect sizes, many adverse effects and do not change the disease course. Therefore, it is critically important to study alternative treatment strateg
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- 2015
65. Exploring the X-ray and gamma-ray properties of the redback millisecond pulsar PSR J1723-2837
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Hui, C. Y., Tam, P. H. T., Takata, J., Kong, A. K. H., Cheng, K. S., Wu, J. H. K., Lin, L. C. C., and Wu, E. M. H.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We have investigated the X-ray and $\gamma$-ray properties of the redback millisecond pulsar PSR J1723-2837 with XMM-Newton, Chandra and Fermi. We have discovered the X-ray orbital modulation of this binary system with the minimum that coincides with the phases of radio eclipse. The X-ray emission is clearly non-thermal in nature which can be well described by a simple power-law with a photon index of $\sim1.2$. The phase-averaged luminosity is $\sim9\times10^{31}$ erg/s in 0.3-10 keV which consumes $\sim0.2\%$ of the spin-down power. We have detected the $\gamma-$ray emission in $0.1-300$ GeV from this system at a significance of $\sim6\sigma$ for the first time. The $\gamma-$rays in this energy range consumes $\sim2\%$ of the spin-down power and can be modeled by a power-law with a photon index of $\sim2.6$. We discuss the high energy properties of the new redback in the context of a intrabinary shock model., Comment: 13 pages, 3 figures, accepted for publication in ApJ Letter
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- 2013
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66. Model on pulsed GeV radiation from magnetars
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Takata, J., Wang, Y., Wu, E. M. H., and Cheng, K. S.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We discuss a possible scenario for radiation mechanism of pulsed GeV gamma-rays from magnetars. The magnetars have shown frequent X-ray bursts, which would be triggered by crust fractures and could release the energy of order of ~10^{41-42}erg. If the location of the crust cracking of the magnetic field is close to the magnetic pole, part of the released energy may excite the Alfevn wave that can propagate into outer magnetosphere. The oscillation of the magnetic field induces the available potential drop ~10^{15}Volts, which can accelerate the electrons and/or positrons to the Lorentz factor ~10^{7} in the outer magnetosphere. The curvature radiation process at outer magnetosphere can produce GeV gamma-rays. If the radiation process is occurred above r~5x 10^7cm from the stellar surface, the emitted GeV gamma-rays can escape from the pair-creation process with the X-rays and/or the magnetic field. The expected luminosity of the GeV emissions is order of L_{\gamma}< 10^{35} erg/s, and the radiation process will last for a temporal scale of years. The expected pulse profiles have a broad shape with sometimes sharp peaks. We apply the model to AXP 1E~2259+586., Comment: 22 pages, 6 figures, accepted to MNRAS
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- 2013
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67. Search for pulsed gamma-ray emission from globular cluster M28
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Wu, J. H. K., Hui, C. Y., Wu, E. M. H., Kong, A. K. H., Huang, R. H. H., Tam, P. H. T., Takata, J., and Cheng, K. S.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Using the data from the Large Area Telescope on board the Fermi Gamma-ray Space Telescope, we have searched for the gamma-ray pulsations from the direction of globular cluster M28 (NGC 6626). We report the discovery of a signal with the frequency consistent with that of the energetic millisecond pulsar (MSP) PSR B1821-24 in M28. A weighted H-test test statisic (TS) of 28.8 is attained which corresponds to a chance probability of ~1e-5 (4.3-sigma detection). With a phase-resolved analysis, the pulsed component is found to contribute ~25% of the total observed gamma-ray emission from the cluster. On the other hand, the unpulsed level provides a constraint for the underlying MSP population and the fundamental plane relations for the scenario of inverse Compton scattering. Follow-up timing observations in radio/X-ray are encouraged for further investigating this periodic signal candidate., Comment: 8 pages, 2 figures, 2 tables, accepted for publication in ApJ Letter
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- 2013
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68. Comparison between two commercially available Luminex non-HLA antibody assays
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Gimferrer, I., Youngs, D., and Chou-Wu, E.
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- 2024
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69. HLA-DP antibodies targeting combined DPB1/DPA1 epitopes
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Youngs, D., Gimferrer, I., and Chou-Wu, E.
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- 2024
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70. Assessing DQB1 immunogenicity using the two mismatches one DSA approach in a local kidney transplant cohort
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Chou-Wu, E. and Gimferrer, I.
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- 2024
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71. Direct Measurement of Non-Classical Photon Statistics with a Multi-Pixel Photon Counter
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Ding, Cheng-Jie, Rong, You-Ying, Chen, Yu, Chen, Xiu-Liang, and Wu, E
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- 2019
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72. Reducing off target viral delivery in ovarian cancer gene therapy using a protease-activated AAV2 vector platform
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Tong, J.G., Evans, A.C., Ho, M.L., Guenther, C.M., Brun, M.J., Judd, J., Wu, E., and Suh, J.
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- 2019
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73. Grief, depressive symptoms, and inflammation in the spousally bereaved
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Fagundes, Christopher P., Brown, Ryan L., Chen, Michelle A., Murdock, Kyle W., Saucedo, Levi, LeRoy, Angie, Wu, E. Lydia, Garcini, Luz M., Shahane, Anoushka D., Baameur, Faiza, and Heijnen, Cobi
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- 2019
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74. Orbital Phase Dependent Gamma-ray emissions from the Black Widow Pulsar
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Wu, E. M. H., Takata, J., Cheng, K. S., Huang, R. H. H., Hui, C. Y., Kong, A. K. H., Tam, P. H. T., and Wu, J. H. K.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report on evidence for orbital phase-dependence of the gamma-ray emission from PSR B1957+20 black widow system by using the data of the Fermi Large Area Telescope. We divide an orbital cycle into two regions: a region containing the inferior conjunction, and the other region containing rest of the orbital cycle. We show that the observed spectra for the different orbital regions are fitted by different functional forms. The spectrum of the orbital region containing inferior conjunction can be described by a power-law with an exponential cutoff (PLE) model, which gives the best-fit model for the orbital phase that does not contain the inferior conjunction, plus an extra component above ~2.7 GeV. The emission above 3 GeV in this region is detected with a ~7-sigma confidence level. The gamma-ray data above ~2.7 GeV are observed to be modulated at the orbital period at the ~2.3-sigma level. We anticipate that the PLE component dominating below ~2.7 GeV originates from the pulsar magnetosphere. We also show that the inverse-Compton scattering of the thermal radiation of the companion star off a "cold" ultra-relativistic pulsar wind can explain the extra component above ~2.7 GeV. The black widow pulsar PSR B1957+20 may be the member of a new class of object, in the sense that the system is showing gamma-ray emission with both magnetospheric and pulsar wind origins., Comment: 18 pages, 6 figures, 1 table, accepted for publication in The Astrophysical Journal
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- 2012
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75. Pulsed {\gamma}-ray emission from magnetar 1E 2259+586
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Wu, J. H. K., Hui, C. Y., Huang, R. H. H., Kong, A. K. H., Cheng, K. S., Takata, J., Tam, P. H. T., Wu, E. M. H., and Liu, C. -Y.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Anomalous x-ray pulsars (AXPs) are thought to be magnetars which are young isolated neutron stars with extremely strong magnetic fields of > 10^14Gauss. Their tremendous magnetic fields inferred from the spin parameters provide a huge energy reservoir to power the observed x-ray emission. High-energy emission above 0.3 MeV has never been detected despite intensive search. Here, we present the possible Fermi Large Area Telescope (LAT) detection of {\gamma}-ray pulsations above 200 MeV from the AXP, 1E 2259+586, which puts the current theoretical models of {\gamma}-ray emission mechanisms of magnetars into challenge. We speculate that the high-energy {\gamma}-rays originate from the outer magnetosphere of the magnetar., Comment: Proceedings of IAUS 291 "Neutron Stars and Pulsars: Challenges and Opportunities after 80 years", J. van Leeuwen (ed.); 3 pages, 2 figures
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- 2012
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76. Discovery of {\gamma}-ray pulsation and X-ray emission from the black widow pulsar PSR J2051-0827
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Wu, J. H. K., Kong, A. K. H., Huang, R. H. H., Takata, J., Tam, P. H. T., Wu, E. M. H., and Cheng, K. S.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report the discovery of pulsed {\gamma}-ray emission and X-ray emission from the black widow millisecond pulsar PSR J2051-0827 by using the data from the Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope and the Advanced CCD Imaging Spectrometer array (ACIS-S) on the Chandra X-ray Observatory. Using 3 years of LAT data, PSR J2051-0827 is clearly detected in {\gamma}-ray with a signicance of \sim 8{\sigma} in the 0.2 - 20 GeV band. The 200 MeV - 20 GeV {\gamma}-ray spectrum of PSR J2051-0827 can be modeled by a simple power- law with a photon index of 2.46 \pm 0.15. Significant (\sim 5{\sigma}) {\gamma}-ray pulsations at the radio period were detected. PSR J2051-0827 was also detected in soft (0.3-7 keV) X-ray with Chandra. By comparing the observed {\gamma}-rays and X-rays with theoretical models, we suggest that the {\gamma}-ray emission is from the outer gap while the X-rays can be from intra-binary shock and pulsar magnetospheric synchrotron emissions., Comment: 10 pages, 4 figures, accepted by ApJ on Jan 28, 2012
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- 2012
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77. Comparative Effectiveness of a Second Tumor Necrosis Factor Inhibitor Versus a Non–Tumor Necrosis Factor Biologic in the Treatment of Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis
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Mannion, Melissa L., Amin, Shahla, Balevic, Stephen, Chang, Min‐Lee, Correll, Colleen K., Kearsley‐Fleet, Lianne, Hyrich, Kimme L., Beukelman, Timothy, Aamir, R., Abulaban, K., Adams, A., Aguiar Lapsia, C., Akinsete, A., Akoghlanian, S., Al Manaa, M., AlBijadi, A., Allenspach, E., Almutairi, A., Alperin, R., Amarilyo, G., Ambler, W., Amoruso, M., Angeles‐Han, S., Ardoin, S., Armendariz, S., Asfaw, L., Aviran Dagan, N., Bacha, C., Balboni, I., Balevic, S., Ballinger, S., Baluta, S., Barillas‐Arias, L., Basiaga, M., Baszis, K., Baxter, S., Becker, M., Begezda, A., Behrens, E., Beil, E., Benseler, S., Bermudez‐Santiago, L., Bernal, W., Bigley, T., Bingham, C., Binstadt, B., Black, C., Blackmon, B., Blakley, M., Bohnsack, J., Boneparth, A., Bradfield, H., Bridges, J., Brooks, E., Brothers, M., Brunner, H., Buckley, L., Buckley, M., Buckley, M., Bukulmez, H., Bullock, D., Canna, S., Cannon, L., Canny, S., Cartwright, V., Cassidy, E., Castro, D., Chalom, E., Chang, J., Chang, M., Chang, J., Chang‐Hoftman, A., Chen, A., Chiraseveenuprapund, P., Ciaglia, K., Co, D., Cohen, E., Collinge, J., Conlon, H., Connor, R., Cook, K., Cooper, A., Cooper, J., Corbin, K., Correll, C., Cron, R., Curry, M., Dalrymple, A., Datyner, E., Davis, T., De Ranieri, D., Dean, J., DeCoste, C., Dedeoglu, F., DeGuzman, M., Delnay, N., DeSantis, E., Devine, R., Dhalla, M., Dhanrajani, A., Dissanayake, D., Dizon, B., Drapeau, N., Drew, J., Driest, K., Du, Q., Duncan, E., Dunnock, K., Durkee, D., Dvergsten, J., Eberhard, A., Ede, K., Edelheit, B., Edens, C., El Tal, T., Elder, M., Elzaki, Y., Fadrhonc, S., Failing, C., Fair, D., Favier, L., Feldman, B., Fennell, J., Ferguson, P., Ferguson, I., Figueroa, C., Flanagan, E., Fogel, L., Fox, E., Fox, M., Franklin, L., Fuhlbrigge, R., Fuller, J., Furey, M., Futch‐West, T., Gagne, S., Gennaro, V., Gerstbacher, D., Gilbert, M., Gironella, A., Glaser, D., Goh, I., Goldsmith, D., Gorry, S., Goswami, N., Gottlieb, B., Graham, T., Grevich, S., Griffin, T., Grim, A., Grom, A., Guevara, M., Hahn, T., Halyabar, O., Hamda Natur, M., Hammelev, E., Hammond, T., Harel, L., Harris, J., Harry, O., Hausmann, J., Hay, A., Hays, K., Hayward, K., Henderson, L., Henrickson, M., Hersh, A., Hickey, K., Hiraki, L., Hiskey, M., Hobday, P., Hoffart, C., Holland, M., Hollander, M., Hong, S., Horton, D., Horwitz, M., Hsu, J., Huber, A., Huberts, A., Huggins, J., Huie, L., Hui‐Yuen, J., Ibarra, M., Imlay, A., Imundo, L., Inman, C., Jackson, A., James, K., Janow, G., Jared, S., Jiang, Y., Johnson, L., Johnson, N., Jones, J., Kafisheh, D., Kahn, P., Kaidar, K., Kasinathan, S., Kaur, R., Kessler, E., Kienzle, B., Kim, S., Kimura, Y., Kingsbury, D., Kitcharoensakkul, M., Klausmeier, T., Klein, K., Klein‐Gitelman, M., Knight, A., Kovalick, L., Kramer, S., Kremer, C., Kudas, O., LaFlam, T., Lang, B., Lapidus, S., Lapin, B., Lasky, A., Lawler, C., Lawson, E., Laxer, R., Lee, P., Lee, P., Lee, T., Lee, A., Leisinger, E., Lentini, L., Lerman, M., Levinsky, Y., Levy, D., Li, S., Lieberman, S., Lim, L., Limenis, E., Lin, C., Ling, N., Lionetti, G., Livny, R., Lloyd, M., Lo, M., Long, A., Lopez‐Peña, M., Lovell, D., Luca, N., Lvovich, S., Lytch, A., Ma, M., Machado, A., MacMahon, J., Madison, J., Mannion, M., Manos, C., Mansfield, L., Marston, B., Mason, T., Matchett, D., McAllister, L., McBrearty, K., McColl, J., McCurdy, D., McDaniels, K., McDonald, J., Meidan, E., Mellins, E., Mian, Z., Miettunen, P., Miller, M., Milojevic, D., Mitacek, R., Modica, R., Mohan, S., Moore, T., Moore, K., Moorthy, L., Moreno, J., Morgan, E., Moyer, A., Murante, B., Murphy, A., Muscal, E., Mwizerwa, O., Najafi, A., Nanda, K., Nasah, N., Nassi, L., Nativ, S., Natter, M., Nearanz, K., Neely, J., Newhall, L., Nguyen, A., Nigrovic, P., Nocton, J., Nolan, B., Nowicki, K., Oakes, R., Oberle, E., Ogbonnaya‐Whittesley, S., Ogbu, E., Oliver, M., Olveda, R., Onel, K., Orandi, A., Padam, J., Paller, A., Pan, N., Pandya, J., Panupattanapong, S., Toledano, A. Pappo, Parsons, A., Patel, J., Patel, P., Patrick, A., Patrizi, S., Paul, S., Perfetto, J., Perron, M., Peskin, M., Ponder, L., Pooni, R., Prahalad, S., Puplava, B., Quinlan‐Waters, M., Rabinovich, C., Rafko, J., Rahimi, H., Rampone, K., Ramsey, S., Randell, R., Ray, L., Reed, A., Reed, A., Reid, H., Reiff, D., Richins, S., Riebschleger, M., Rife, E., Riordan, M., Riskalla, M., Robinson, A., Robinson, L., Rodgers, L., Rodriquez, M., Rogers, D., Ronis, T., Rosado, A., Rosenkranz, M., Rosenwasser, N., Rothermel, H., Rothman, D., Rothschild, E., Roth‐Wojcicki, E., Rouster‐Stevens, K., Rubinstein, T., Rupp, J., Ruth, N., Sabbagh, S., Sadun, R., Santiago, L., Saper, V., Sarkissian, A., Scalzi, L., Schahn, J., Schikler, K., Schlefman, A., Schmeling, H., Schmitt, E., Schneider, R., Schulert, G., Schultz, K., Schutt, C., Seper, C., Sheets, R., Shehab, A., Shenoi, S., Sherman, M., Shirley, J., Shishov, M., Siegel, D., Singer, N., Sivaraman, V., Sloan, E., Smith, C., Smith, J., Smitherman, E., Soep, J., Son, Mary B., Sosna, D., Spencer, C., Spiegel, L., Spitznagle, J., Srinivasalu, H., Stapp, H., Steigerwald, K., Stephens, A., Sterba Rakovchik, Y., Stern, S., Stevens, B., Stevenson, R., Stewart, K., Stewart, W., Stingl, C., Stoll, M., Stringer, E., Sule, S., Sullivan, J., Sundel, R., Sutter, M., Swaffar, C., Swayne, N., Syed, R., Symington, T., Syverson, G., Szymanski, A., Taber, S., Tal, R., Tambralli, A., Taneja, A., Tanner, T., Tarvin, S., Tate, L., Taxter, A., Taylor, J., Tesher, M., Thakurdeen, T., Theisen, A., Thomas, B., Thomas, L., Thomas, N., Ting, T., Todd, C., Toib, D., Toib, D., Torok, K., Tory, H., Toth, M., Tse, S., Tsin, C., Twachtman‐Bassett, J., Twilt, M., Valcarcel, T., Valdovinos, R., Vallee, A., Van Mater, H., Vandenbergen, S., Vannoy, L., Varghese, C., Vasquez, N., Vega‐Fernandez, P., Velez, J., Verbsky, J., Verstegen, R., Scheven, E., Vora, S., Wagner‐Weiner, L., Wahezi, D., Waite, H., Walker, B., Walters, H., Waterfield, M., Waters, A., Weiser, P., Weiss, P., Weiss, J., Wershba, E., Westheuser, V., White, A., Widrick, K., Williams, C., Wong, S., Woolnough, L., Wright, T., Wu, E., Yalcindag, A., Yasin, S., Yeung, R., Yomogida, K., Zeft, A., Zhang, Y., Zhao, Y., and Zhu, A.
- Abstract
The objective of this study was to compare the effectiveness of a second tumor necrosis factor inhibitor (TNFi) versus a non‐TNFi biologic following discontinuation of a TNFi for patients with polyarticular‐course juvenile idiopathic arthritis (pJIA). Using the Childhood Arthritis and Rheumatology Research Alliance Registry, patients with pJIA who started receiving a second biologic following a first TNFi were identified. Patients were required to have no active uveitis on the index date and a visit six months after the index date. Outcome measures included Clinical Juvenile Arthritis Disease Activity Score with a maximum of 10 active joints (cJADAS10), cJADAS10 inactive disease (ID; ≤2.5) and cJADAS10 minimal disease activity (MiDA; ≤5). Multiple imputation was used to account for missing data. Adjusted odds ratios (aORs) were calculated using propensity score quintiles to compare outcomes at six months following second biologic initiation. There were 216 patients included, 84% initially received etanercept, and most patients stopped receiving it because of its ineffectiveness (74%). A total of 183 (85%) started receiving a second TNFi, and 33 (15%) started receiving a non‐TNFi. Adalimumab was the most common second biologic received (71% overall, 84% of second TNFi), and tocilizumab was the most common non‐TNFi second biologic received (9% overall, 58% of non‐TNFi). There was no difference between receiving TNFi versus non‐TNFi in cJADAS10 ID (29% vs 25%; aOR 1.23, 95% confidence interval [CI] 0.47–3.20) or at least MiDA (43% vs 39%; aOR 1.11, 95% CI 0.47–2.62) at six months. Most patients with pJIA started receiving TNFi rather than non‐TNFi as their second biologic, and there were no differences in disease activity at six months.
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- 2024
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78. Down Syndrome–Associated Arthritis Cohort in the New Childhood Arthritis and Rheumatology Research Alliance Registry: Clinical Characteristics, Treatment, and Outcomes
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Jones, Jordan T., Smith, Chelsey, Becker, Mara L., Lovell, Daniel, Abel, N., Abulaban, K., Adams, A., Adams, M., Agbayani, R., Akoghlanian, S., Al Ahmed, O., Allenspach, E., Alperin, R., Alpizar, M., Amarilyo, G., Anastasopoulos, D., Anderson, E., Andrew, M., Ardalan, K., Ardoin, S., Baker, E., Balboni, I., Balevic, S., Ballenger, L., Ballinger, S., Balmuri, N., Barbar‐Smiley, F., Barillas‐Arias, L., Basiaga, M., Baszis, K., Bell‐Brunson, H., Beltz, E., Benham, H., Benseler, S., Bernal, W., Beukelman, T., Bigley, T., Binstadt, B., Birmingham, J., Black, C., Blakley, M., Bohnsack, J., Boland, J., Boneparth, A., Bowman, S., Brooks, E., Brown, A., Brunner, H., Buckley, M., Buckley, M., Bukulmez, H., Bullington, A., Bullock, D., Cameron, B., Canna, S., Cannon, L., Carpenter, S., Carper, P., Cartwright, V., Cassidy, E., Cerracchio, L., Chalom, E., Chang, J., Chang‐Hoftman, A., Chauhan, V., Chira, P., Chiu, Y., Chundru, K., Clairman, H., Co, D., Collins, K., Confair, A., Conlon, H., Connor, R., Cooper, A., Cooper, J., Cooper, S., Correll, C., Corvalan, R., Cospito, T., Costanzo, D., Cron, R., Curry, M., Dalrymple, A., Davis, A., Davis, C., Davis, C., Davis, T., De Ranieri, D., Dean, J., Dedeoglu, F., DeGuzman, M., Delnay, N., Dempsey, V., DeSantis, E., Dickson, T., Dingle, J., Dionizovik‐Dimanovski, M., Donaldson, B., Dorsey, E., Dover, S., Dowling, J., Drew, J., Driest, K., Drummond, K., Du, Q., Duarte, K., Durkee, D., Duverger, E., Dvergsten, J., Eberhard, A., Eckert, M., Ede, K., Edens, C., Edens, C., Edgerly, Y., Elder, M., Fadrhonc, S., Failing, C., Fair, D., Falcon, M., Favier, L., Feldman, B., Ferguson, I., Ferguson, P., Ferreira, B., Ferrucho, R., Fields, K., Finkel, T., Fitzgerald, M., Fleck, D., Fleming, C., Flynn, O., Fogel, L., Fox, E., Fox, M., Franco, L., Freeman, M., Froese, S., Fuhlbrigge, R., Fuller, J., George, N., Gergely, T., Gerhold, K., Gerstbacher, D., Gilbert, M., Gillispie‐Taylor, M., Giverc, E., Goh, I., Goldberg, T., Goldsmith, D., Gotschlich, E., Gotte, A., Gottlieb, B., Gracia, C., Graham, T., Grevich, S., Griffin, T., Griswold, J., Guevara, M., Guittar, P., Gurion, R., Guzman, M., Hahn, T., Halyabar, O., Hammelev, E., Hance, M., Hansman, E., Hanson, A., Harel, L., Haro, S., Harris, J., Hartigan, E., Hausmann, J., Hay, A., Hayward, K., Heiart, J., Hekl, K., Henderson, L., Henrickson, M., Hersh, A., Hickey, K., Hillyer, S., Hiraki, L., Hiskey, M., Hobday, P., Hoffart, C., Holland, M., Hollander, M., Hong, S., Horwitz, M., Hsu, J., Huber, A., Huggins, J., Hughes, R., Hui‐Yuen, J., Hung, C., Huntington, J., Huttenlocher, A., Ibarra, M., Imundo, L., Inman, C., Iqbal, S., Jackson, A., Jackson, S., James, K., Janow, G., Jaquith, J., Jared, S., Johnson, N., Jones, J., Jones, J., Jones, J., Jones, K., Jones, S., Joshi, S., Jung, L., Justice, C., Justiniano, A., Kahn, P., Karan, N., Kaufman, K., Kemp, A., Kessler, E., Khaleel, M., Khalsa, U., Kienzle, B., Kim, S., Kimura, Y., Kingsbury, D., Kitcharoensakkul, M., Klausmeier, T., Klein, K., Klein‐Gitelman, M., Kosikowski, A., Kovalick, L., Kracker, J., Kramer, S., Kremer, C., Lai, J., Lang, B., Lapidus, S., Lasky, A., Latham, D., Lawson, E., Laxer, R., Lee, P., Lee, P., Lee, T., Lentini, L., Lerman, M., Levy, D., Li, S., Lieberman, S., Lim, L., Lin, C., Ling, N., Lingis, M., Lo, M., Lovell, D., Luca, N., Lvovich, S., Ma, M., Mackey, C., Madison, C., Madison, J., Malla, B., Maller, J., Malloy, M., Mannion, M., Manos, C., Marques, L., Martyniuk, A., Mason, T., Mathus, S., McAllister, L., McCallum, B., McCarthy, K., McConnell, K., McCurdy, D., McCurdy Stokes, P., McGuire, S., McHale, I., McHugh, A., McKibben, K., McMonagle, A., McMullen‐Jackson, C., Meidan, E., Mellins, E., Mendoza, E., Mercado, R., Merritt, A., Michalowski, L., Miettunen, P., Miller, M., Mirizio, E., Misajon, E., Mitchell, M., Modica, R., Mohan, S., Moore, K., Moorthy, L., Morgan, S., Morgan Dewitt, E., Morris, S., Moss, C., Moussa, T., Mruk, V., Mulvhihill, E., Muscal, E., Nahal, B., Nanda, K., Nassi, L., Nativ, S., Natter, M., Neely, J., Nelson, B., Newhall, L., Ng, L., Nguyen, E., Nicholas, J., Nigrovic, P., Nocton, J., Oberle, E., Obispo, B., O’Brien, B., O’Brien, T., O’Connor, M., Oliver, M., Olson, J., O’Neil, K., Onel, K., Orlando, M., Oz, R., Pagano, E., Paller, A., Pan, N., Panupattanapong, S., Paredes, J., Parsons, A., Patel, J., Pentakota, K., Pepmueller, P., Pfeiffer, T., Phillippi, K., Phillippi, K., Ponder, L., Pooni, R., Prahalad, S., Pratt, S., Protopapas, S., Punaro, M., Puplava, B., Quach, J., Quinlan‐Waters, M., Quintero, A., Rabinovich, C., Radhakrishna, S., Rafko, J., Raisian, J., Rakestraw, A., Ramsay, E., Ramsey, S., Reed, A., Reed, A., Reed, A., Reid, H., Reyes, A., Richmond, A., Riebschleger, M., Ringold, S., Riordan, M., Riskalla, M., Ritter, M., Rivas‐Chacon, R., Roberson, S., Robinson, A., Rodela, E., Rodriquez, M., Rojas, K., Ronis, T., Rosenkranz, M., Rosenwasser Raines, N., Rosolowski, B., Rothermel, H., Rothman, D., Roth‐Wojcicki, E., Rouster–Stevens, K., Rubinstein, T., Ruth, N., Saad, N., Sabatino, M., Sabbagh, S., Sadun, R., Sandborg, C., Sanni, A., Sarkissian, A., Savani, S., Scalzi, L., Schanberg, L., Scharnhorst, S., Schikler, K., Schmeling, H., Schmidt, K., Schmitt, E., Schneider, R., Schollaert‐Fitch, K., Schulert, G., Seay, T., Seper, C., Shalen, J., Sheets, R., Shelly, A., Shen, B., Shenoi, S., Shergill, K., Shiff, N., Shirley, J., Shishov, M., Silverman, E., Singer, N., Sivaraman, V., Sletten, J., Smith, A., Smith, C., Smith, J., Smith, J., Smitherman, E., Snider, C., Soep, J., Son, M., Soybilgic, A., Spence, S., Spiegel, L., Spitznagle, J., Sran, R., Srinivasalu, H., Stapp, H., Stasek, J., Steigerwald, K., Sterba Rakovchik, Y., Stern, S., Stevens, A., Stevens, B., Stevenson, R., Stewart, K., Stingl, C., Stokes, J., Stoll, M., Stoops, S., Strelow, J., Stringer, E., Sule, S., Sumner, J., Sundel, R., Sura, A., Sutter, M., Syed, R., Taber, S., Tal, R., Tambralli, A., Taneja, A., Tanner, T., Tapani, S., Tarshish, G., Tarvin, S., Tate, L., Taxter, A., Taylor, J., Terry, M., Tesher, M., Thatayatikom, A., Thomas, B., Ting, T., Tipp, A., Toib, D., Torok, K., Toruner, C., Tory, H., Toth, M., Treemarcki, E., Tse, S., Tubwell, V., Twilt, M., Uriguen, S., Valcarcel, T., Van Mater, H., Vannoy, L., Varghese, C., Vasquez, N., Vazzana, K., Vega‐Fernandes, P., Vehe, R., Veiga, K., Velez, J., Verbsky, J., Volpe, N., von Scheven, E., Vora, S., Wagner, J., Wagner‐Weiner, L., Wahezi, D., Waite, H., Walker, J., Walters, H., Wampler Muskardin, T., Wang, C., Waqar, L., Waterfield, M., Watson, M., Watts, A., Waugaman, B., Weiser, P., Weiss, J., Weiss, P., Wershba, E., White, A., Williams, C., Wise, A., Woo, J., Woolnough, L., Wright, T., Wu, E., Yalcindag, A., Yee, M., Yen, E., Yeung, R., Yomogida, K., Yu, Q., Zapata, R., Zartoshti, A., Zeft, A., Zeft, R., Zemel, L., Zhang, Y., Zhao, Y., Zhu, A., and Zic, C.
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- 2021
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79. XMM-Newton observation of PSR B2224+65 and its jet
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Hui, C. Y., Huang, R. H. H., Trepl, L., Tetzlaff, N., Takata, J., Wu, E. M. H., and Cheng, K. S.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We have investigated the pulsar PSR B2224+65 and its X-ray jet with XMM-Newton. Apart from the long X-ray jet which is almost perpendicular to the direction of proper motion, a putative extended feature at the pulsar position, which oriented in the opposite direction of the proper motion, is also suggested by this deep X-ray imaging. Non-detection of any coherent X-ray pulsation disfavors the magnetospheric origin of the X-rays observed from the position of PSR B2224+65 and hence suggest that the interpretation of pulsar wind nebula is more viable. We have also probed the origin of PSR B2224+65 and identified a runaway star, which possibly originated from the Cygnus OB9 association, as a candidate for the former binary companion of the neutron star's progenitor., Comment: 24 pages, 8 figures, 3 tables, accepted for publication in ApJ
- Published
- 2011
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80. Discovery of gamma-ray emission from the supernova remnant Kes 17 with Fermi Large Area Telescope
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Wu, J. H. K., Wu, E. M. H., Hui, C. Y., Tam, P. H. T., Huang, R. H. H., Kong, A. K. H., and Cheng, K. S.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report the discovery of GeV emission at the position of supernova remnant Kes 17 by using the data from the Large Area Telescope on board the Fermi Gamma-ray Space Telescope. Kes 17 can be clearly detected with a significance of ~12 sigma in the 1 - 20 GeV range. Moreover, a number of gamma-ray sources were detected in its vicinity. The gamma-ray spectrum of Kes 17 can be well described by a simple power-law with a photon index of ~ 2.4. Together with the multi-wavelength evidence for its interactions with the nearby molecular cloud, the gamma-ray detection suggests that Kes 17 is a candidate acceleration site for cosmic-rays., Comment: 13 pages, 3 figures, 1 table, accepted for publication in ApJ Letter
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- 2011
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81. Exploring the dark accelerator HESS J1745-303 with Fermi Large Area Telescope
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Hui, C. Y., Wu, E. M. H., Wu, J. H. K., Huang, R. H. H., Cheng, K. S., Tam, P. H. T., and Kong, A. K. H.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present a detailed analysis of the gamma-ray emission from HESS J1745-303 with the data obtained by the Fermi Gamma-ray Space Telescope in the first ~29 months observation.The source can be clearly detected at the level of ~18-sigma and ~6-sigma in 1-20 GeV and 10-20 GeV respectively. Different from the results obtained by the Compton Gamma-ray Observatory, we do not find any evidence of variability. Most of emission in 10-20 GeV is found to coincide with the region C of HESS J1745-303. A simple power-law is sufficient to describe the GeV spectrum with a photon index of ~2.6. The power-law spectrum inferred in the GeV regime can be connected to that of a particular spatial component of HESS J1745-303 in 1-10 TeV without any spectral break. These properties impose independent constraints for understanding the nature of this "dark particle accelerator"., Comment: 8 pages, 3 figures, 1 table, accepted for publication in ApJ
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- 2011
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82. The QUaD Galactic Plane Survey II: A Compact Source Catalog
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Culverhouse, T., Ade, P., Bock, J., Bowden, M., Brown, M. L., Cahill, G., Castro, P. G., Church, S., Friedman, R., Ganga, K., Gear, W. K., Gupta, S., Hinderks, J., Kovac, J., Lange, A. E., Leitch, E., Melhuish, S. J., Memari, Y., Murphy, J. A., Orlando, A., Pryke, C., Schwarz, R., O'Sullivan, C., Piccirillo, L., Rajguru, N., Rusholme, B., Taylor, A. N., Thompson, K. L., Turner, A. H., Wu, E. Y. S., and Zemcov, M.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present a catalog of compact sources derived from the QUaD Galactic Plane Survey. The survey covers ~800 square degrees of the inner galaxy (|b|<4 degrees) in Stokes I, Q and U parameters at 100 and 150 GHz, with angular resolution 5 and 3.5 arcminutes. 505 unique sources are identified in I, of which 239 are spatially matched between frequency bands, with 50 (216) detected at 100 (150) GHz alone; 182 sources are identified as ultracompact HII (UCHII) regions. Approximating the distribution of total intensity source fluxes as a power-law, we find a slope of $\gamma_{S,100}=-1.8\pm0.4$ at 100 GHz, and $\gamma_{S,150}=-2.2\pm0.4$ at 150 GHz. Similarly, the power-law index of the source two-point angular correlation function is $\gamma_{\theta,100}=-1.21\pm0.04$ and $\gamma_{\theta,150}=-1.25\pm0.04$. The total intensity spectral index distribution peaks at $\alpha_{I}\sim0.25$, indicating that dust emission is not the only source of radiation produced by these objects between 100 and 150 GHz; free-free radiation is likely significant in the 100 GHz band. Four sources are detected in polarized intensity P, of which three have matching counterparts in I. Three of the polarized sources lie close to the galactic center, Sagittarius A*, Sagittarius B2 and the Galactic Radio Arc, while the fourth is RCW 49, a bright HII region. An extended polarized source, undetected by the source extraction algorithm on account of its $\sim0.5^{\circ}$ size, is identified visually, and is an isolated example of large-scale polarized emission oriented distinctly from the bulk galactic dust polarization., Comment: 30 pages, 19 figures, two catalogs; submitted to ApJS; maps and catalogs downloadable from
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- 2010
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83. Experimental demonstration of counterfactual quantum key distribution
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Ren, Min, Wu, Guang, Wu, E, and Zeng, Heping
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Quantum Physics - Abstract
Counterfactual quantum key distribution provides natural advantage against the eavesdropping on the actual signal particles. It can prevent the photon-number-splitting attack when a weak coherent light source is used for the practical implementation. We realized the counterfactual quantum key distribution in an unbalanced Mach-Zehnder interferometer of 12.5-km-long quantum channel with a high-fringe visibility of 96:4%. As a result, we obtained secure keys against the noise-induced attack (eg. the vacuum attack) and passive photon-number-splitting attack., Comment: 5 pages, 3 figures
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- 2010
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84. The QUaD Galactic Plane Survey 1: Maps And Analysis of Diffuse Emission
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Culverhouse, T., Ade, P., Bock, J., Bowden, M., Brown, M. L., Cahill, G., Castro, P. G., Church, S., Friedman, R., Ganga, K., Gear, W. K., Gupta, S., Hinderks, J., Kovac, J., Lange, A. E., Leitch, E., Melhuish, S. J., Memari, Y., Murphy, J. A., Orlando, A., Schwarz, R., Sullivan, C. O', Piccirillo, L., Pryke, C., Rajguru, N., Rusholme, B., Taylor, A. N., Thompson, K. L., Turner, A. H., Wu, E. Y. S., and Zemcov, M.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present a survey of ~800 square degrees of the galactic plane observed with the QUaD telescope. The primary product of the survey are maps of Stokes I, Q and U parameters at 100 and 150 GHz, with spatial resolution 5 and 3.5 arcminutes respectively. Two regions are covered, spanning approximately 245-295 and 315-5 degrees in galactic longitude l, and -4
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- 2010
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85. Parameter Estimation from Improved Measurements of the CMB from QUaD
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QUaD collaboration, Gupta, S., Ade, P., Bock, J., Bowden, M., Brown, M. L., Cahill, G., Castro, P. G., Church, S., Culverhouse, T., Friedman, R. B., Ganga, K., Gear, W. K., Hinderks, J., Kovac, J., Lange, A. E., Leitch, E., Melhuish, S. J., Memari, Y., Murphy, J. A., Orlando, A., O'Sullivan, C., Piccirillo, L., Pryke, C., Rajguru, N., Rusholme, B., Schwarz, R., Taylor, A. N., Thompson, K. L., Turner, A. H., Wu, E. Y. S., and Zemcov, M.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We evaluate the contribution of cosmic microwave background (CMB) polarization spectra to cosmological parameter constraints. We produce cosmological parameters using high-quality CMB polarization data from the ground-based QUaD experiment and demonstrate for the majority of parameters that there is significant improvement on the constraints obtained from satellite CMB polarization data. We split a multi-experiment CMB dataset into temperature and polarization subsets and show that the best-fit confidence regions for the LCDM 6-parameter cosmological model are consistent with each other, and that polarization data reduces the confidence regions on all parameters. We provide the best limits on parameters from QUaD EE/BB polarization data and we find best-fit parameters from the multi-experiment CMB dataset using the optimal pivot scale of k_p=0.013 Mpc-1 to be {omch2, ombh2, H_0, A_s, n_s, tau}= {0.113, 0.0224, 70.6, 2.29 times 10^-9, 0.960, 0.086}., Comment: 7 pages, 5 figures, updated to reflect published version, minor changes to spelling and format
- Published
- 2009
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86. Characterization of the Millimeter-Wave Polarization of Centaurus A with QUaD
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Zemcov, M., Ade, P., Bock, J., Bowden, M., Brown, M. L., Cahill, G., Castro, P. G., Church, S., Culverhouse, T., Friedman, R. B., Ganga, K., Gear, W. K., Gupta, S., Hinderks, J., Kovac, J., Lange, A. E., Leitch, E., Melhuish, S. J., Memari, Y., Murphy, J. A., Orlando, A., O'Sullivan, C., Piccirillo, L., Pryke, C., Rajguru, N., Rusholme, B., Schwarz, R., Taylor, A. N., Thompson, K. L., Turner, A. H., and Wu, E. Y. S.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Centaurus (Cen) A represents one of the best candidates for an isolated, compact, highly polarized source that is bright at typical cosmic microwave background (CMB) experiment frequencies. We present measurements of the 4 degree by 2 degree region centered on Cen A with QUaD, a CMB polarimeter whose absolute polarization angle is known to 0.5 degrees. Simulations are performed to assess the effect of misestimation of the instrumental parameters on the final measurement and systematic errors due to the field's background structure and temporal variability from Cen A's nuclear region are determined. The total (Q, U) of the inner lobe region is (1.00 +/- 0.07 (stat.) +/- 0.04 (sys.), -1.72 +/- 0.06 +/- 0.05) Jy at 100 GHz and (0.80 +/- 0.06 +/- 0.06, -1.40 +/- 0.07 +/- 0.08) Jy at 150 GHz, leading to polarization angles and total errors of -30.0 +/- 1.1 degrees and -29.1 +/- 1.7 degrees. These measurements will allow the use of Cen A as a polarized calibration source for future millimeter experiments., Comment: 9 pages, 8 figures, v2 matches version published in ApJ
- Published
- 2009
- Full Text
- View/download PDF
87. Improved measurements of the temperature and polarization of the CMB from QUaD
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The QUaD collaboration, Brown, M. L., Ade, P., Bock, J., Bowden, M., Cahill, G., Castro, P. G., Church, S., Culverhouse, T., Friedman, R. B., Ganga, K., Gear, W. K., Gupta, S., Hinderks, J., Kovac, J., Lange, A. E., Leitch, E., Melhuish, S. J., Memari, Y., Murphy, J. A., Orlando, A., O'Sullivan, C., Piccirillo, L., Pryke, C., Rajguru, N., Rusholme, B., Schwarz, R., Taylor, A. N., Thompson, K. L., Turner, A. H., Wu, E. Y. S., and Zemcov, M.
- Subjects
Astrophysics - Cosmology and Extragalactic Astrophysics - Abstract
We present an improved analysis of the final dataset from the QUaD experiment. Using an improved technique to remove ground contamination, we double the effective sky area and hence increase the precision of our CMB power spectrum measurements by ~30% versus that previously reported. In addition, we have improved our modeling of the instrument beams and have reduced our absolute calibration uncertainty from 5% to 3.5% in temperature. The robustness of our results is confirmed through extensive jackknife tests and by way of the agreement we find between our two fully independent analysis pipelines. For the standard 6-parameter LCDM model, the addition of QUaD data marginally improves the constraints on a number of cosmological parameters over those obtained from the WMAP experiment alone. The impact of QUaD data is significantly greater for a model extended to include either a running in the scalar spectral index, or a possible tensor component, or both. Adding both the QUaD data and the results from the ACBAR experiment, the uncertainty in the spectral index running is reduced by ~25% compared to WMAP alone, while the upper limit on the tensor-to-scalar ratio is reduced from r < 0.48 to r < 0.33 (95% c.l). This is the strongest limit on tensors to date from the CMB alone. We also use our polarization measurements to place constraints on parity violating interactions to the surface of last scattering, constraining the energy scale of Lorentz violating interactions to < 1.5 x 10^{-43} GeV (68% c.l.). Finally, we place a robust upper limit on the strength of the lensing B-mode signal. Assuming a single flat band power between l = 200 and l = 2000, we constrain the amplitude of B-modes to be < 0.57 micro-K^2 (95% c.l.)., Comment: 23 pages, 19 figures, updated to reflect published version
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- 2009
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88. Self-gravitating astrophysical mass with singular central density vibrating in fundamental mode
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Bastrukov, S. I., Chang, H. -K., Wu, E. -H., and Molodtsova, I. V.
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Physics - Classical Physics ,Physics - Fluid Dynamics - Abstract
The fluid-dynamical model of a self-gravitating mass of viscous liquid with singular density at the center vibrating in fundamental mode is considered in juxtaposition with that for Kelvin fundamental mode in a homogeneous heavy mass of incompressible inviscid liquid. Particular attention is given to the difference between spectral formulae for the frequency and lifetime of $f$-mode in the singular and homogeneous models. The newly obtained results are discussed in the context of theoretical asteroseismology of pre-white dwarf stage of red giants and stellar cocoons -- spherical gas-dust clouds with dense star-forming core at the center., Comment: Mod. Phys. Lett. A, Vol. 24, No. 40 (2009) pp. 3257-3274
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- 2009
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89. Frequency spectrum of toroidal Alfv\'en mode in a neutron star with Ferraro's form of nonhomogeneous poloidal magnetic field
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Bastrukov, S. I., Chang, H. -K., Molodtsova, I. V., Wu, E. H., Chen, G. -T., and Lan, S. -H.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
Using the energy variational method of magneto-solid-mechanical theory of a perfectly conducting elastic medium threaded by magnetic field, the frequency spectrum of Lorentz-force-driven global torsional nodeless vibrations of a neutron star with Ferraro's form of axisymmetric poloidal nonhomogeneous internal and dipole-like external magnetic field is obtained and compared with that for this toroidal Alfv\'en mode in a neutron star with homogeneous internal and dipolar external magnetic field. The relevance of considered asteroseismic models to quasi-periodic oscillations of the X-ray flux during the ultra powerful outbursts of SGR 1806-20 and SGR 1900+14 is discussed., Comment: Accepted for publication in Astrophysics & Space Science
- Published
- 2009
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90. Small Angular Scale Measurements of the CMB Temperature Power Spectrum from QUaD
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QUaD collaboration, Friedman, R. B., Ade, P., Bock, J., Bowden, M., Brown, M. L., Cahill, G., Castro, P. G., Church, S., Culverhouse, T., Ganga, K., Gear, W. K., Gupta, S., Hinderks, J., Kovac, J., Lange, A. E., Leitch, E., Melhuish, S. J., Memari, Y., Murphy, J. A., Orlando, A., Sullivan, C. O', Piccirillo, L., Pryke, C., Rajguru, N., Rusholme, B., Schwarz, R., Taylor, A. N., Thompson, K. L., Turner, A. H., Wu, E. Y. S., and Zemcov, M.
- Subjects
Astrophysics - Cosmology and Extragalactic Astrophysics - Abstract
We present measurements of the cosmic microwave background (CMB) radiation temperature anisotropy in the multipole range 2000
- Published
- 2009
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91. Cosmological Parameters from the QUaD CMB polarization experiment
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QUaD collaboration, Castro, P. G., Ade, P., Bock, J., Bowden, M., Brown, M. L., Cahill, G., Church, S., Culverhouse, T., Friedman, R. B., Ganga, K., Gear, W. K., Gupta, S., Hinderks, J., Kovac, J., Lange, A. E., Leitch, E., Melhuish, S. J., Memari, Y., Murphy, J. A., Orlando, A., Pryke, C., Schwarz, R., O'Sullivan, C., Piccirillo, L., Rajguru, N., Rusholme, B., Taylor, A. N., Thompson, K. L., Turner, A. H., Wu, E. Y. S., and Zemcov, M.
- Subjects
Astrophysics - Cosmology and Extragalactic Astrophysics - Abstract
In this paper we present a parameter estimation analysis of the polarization and temperature power spectra from the second and third season of observations with the QUaD experiment. QUaD has for the first time detected multiple acoustic peaks in the E-mode polarization spectrum with high significance. Although QUaD-only parameter constraints are not competitive with previous results for the standard 6-parameter LCDM cosmology, they do allow meaningful polarization-only parameter analyses for the first time. In a standard 6-parameter LCDM analysis we find the QUaD TT power spectrum to be in good agreement with previous results. However, the QUaD polarization data shows some tension with LCDM. The origin of this 1 to 2 sigma tension remains unclear, and may point to new physics, residual systematics or simple random chance. We also combine QUaD with the five-year WMAP data set and the SDSS Luminous Red Galaxies 4th data release power spectrum, and extend our analysis to constrain individual isocurvature mode fractions, constraining cold dark matter density, alpha(cdmi)<0.11 (95 % CL), neutrino density, alpha(ndi)<0.26 (95 % CL), and neutrino velocity, alpha(nvi)<0.23 (95 % CL), modes. Our analysis sets a benchmark for future polarization experiments., Comment: 8 pages, 5 figures, submitted to ApJ
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- 2009
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92. Polysaccharides from Dendrobium officinale improve obesity‐induced insulin resistance through the gut microbiota and the SOCS3‐mediated insulin receptor substrate‐1 signaling pathway.
- Author
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Jiang, Wei, Tan, Jin, Zhang, Jiacheng, Deng, Xin, He, Xinyue, Zhang, Jin, Liu, Tong, Sun, Rong, Sun, Mengxun, Chen, Kuo, Xu, Tingjia, Yan, Yuling, Moazzami, Ali, Wu, E‐Jiao, Zhan, Jiasui, and Hu, Binhong
- Subjects
INSULIN receptors ,GUT microbiome ,INSULIN resistance ,DENDROBIUM ,CELLULAR signal transduction ,SPRAGUE Dawley rats - Abstract
BACKGROUND: Obesity induces insulin resistance and chronic inflammation, impacting human health. The relationship between obesity, gut microbiota, and regulatory mechanisms has been studied extensively. Dendrobium officinale polysaccharide (DOP), a traditional Chinese herbal medicine, potentially reduces insulin resistance. However, the mechanism through which DOP affects gut microbiota and alleviates obesity‐induced insulin resistance in rats requires further investigation. RESULTS: The current study aimed to assess the impact of DOP on gut microbiota and insulin resistance in rats on a high‐fat diet. The results revealed that DOP effectively reduced blood lipids, glucose disorders, oxidative stress, and inflammatory infiltration in the liver of obese Sprague Dawley rats. This was achieved by downregulating SOCS3 expression and upregulating insulin receptor substrate‐1 (IRS‐1) by regulating the JAK/STAT/SOCS3 signaling pathway. Notably, DOP intervention enhanced the abundance of beneficial gut microbiota and reduced harmful microbiota. Correlation analysis demonstrated significant associations among intestinal microbiota, SOCS3‐mediated IRS‐1 expression, and inflammatory factors. CONCLUSION: Dendrobium officinale polysaccharide regulated the gut microbiota, enhanced IRS‐1 expression, and mitigated liver injury and insulin resistance due to a high‐fat diet. These findings depict the potential anti‐insulin resistance properties of DOP and offer further evidence for addressing obesity and its complications. © 2023 Society of Chemical Industry. [ABSTRACT FROM AUTHOR]
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- 2024
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93. Fundamental vibrational mode in a highly inhomogeneous star
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Bastrukov, S. I., Chang, H. -K., Wu, E. -H., and Molodtsova, I. V.
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Astrophysics - Abstract
The eigenfrequency problem of fundamental vibrational mode in a highly inhomogeneous star, modeled by self-gravitating mass of viscous liquid with singular density at the center, is considered in juxtaposition with that for Kelvin fundamental mode in the liquid star model with uniform density. Particular attention is given to the difference between spectral equations for the frequency and lifetime of f-mode in the singular and homogeneous star models. The newly obtained results are discussed in the context of theoretical asteroseismology of pre-white dwarf stars and stellar cocoons -- spherical gas-dust clouds with dense star-forming core at the center., Comment: 18 pages, 4 figures
- Published
- 2008
94. Parity violation constraints using 2006-2007 QUaD CMB polarization spectra
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QUaD Collaboration, Wu, E. Y. S., Ade, P., Bock, J., Bowden, M., Brown, M. L., Cahill, G., Castro, P. G., Church, S., Culverhouse, T., Friedman, R., Ganga, K., Gear, W. K., Gupta, S., Hinderks, J., Kovac, J., Lange, A. E., Leitch, E., Melhuish, S. J., Memari, Y., Murphy, J. A., Orlando, A., Piccirillo, L., Pryke, C., Rajguru, N., Rusholme, B., Schwarz, R., O'Sullivan, C., Taylor, A. N., Thompson, K. L., Turner, A. H., and Zemcov, M.
- Subjects
Astrophysics ,High Energy Physics - Phenomenology - Abstract
We constrain parity-violating interactions to the surface of last scattering using spectra from the QUaD experiment's second and third seasons of observations by searching for a possible systematic rotation of the polarization directions of CMB photons. We measure the rotation angle due to such a possible "cosmological birefringence" to be 0.55 deg. +/- 0.82 deg. (random) +/- 0.5 deg. (systematic) using QUaD's 100 and 150 GHz TB and EB spectra over the multipole range 200 < l < 2000, consistent with null, and constrain Lorentz violating interactions to < 2^-43 GeV (68% confidence limit). This is the best constraint to date on electrodynamic parity violation on cosmological scales., Comment: 4 pages, 2 figures, accepted to Physical Review Letters. Improved method, updated result and clarified language
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- 2008
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95. QUaD: A High-Resolution Cosmic Microwave Background Polarimeter
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QUaD collaboration, Hinderks, J. R., Ade, P., Bock, J., Bowden, M., Brown, M. L., Cahill, G., Carlstrom, J. E., Castro, P. G., Church, S., Culverhouse, T., Friedman, R., Ganga, K., Gear, W. K., Gupta, S., Harris, J., Haynes, V., Keating, B. G., Kovac, J., Kirby, E., Lange, A. E., Leitch, E., Mallie, O. E., Melhuish, S., Memari, Y., Murphy, J. A., Orlando, A., Schwarz, R., O'Sullivan, C., Piccirillo, L., Pryke, C., Rajguru, N., Rusholme, B., Taylor, A. N., Thompson, K. L., Tucker, C., Turner, A. H., Wu, E. Y. S., and Zemcov, M.
- Subjects
Astrophysics - Abstract
We describe the QUaD experiment, a millimeter-wavelength polarimeter designed to observe the Cosmic Microwave Background (CMB) from a site at the South Pole. The experiment comprises a 2.64 m Cassegrain telescope equipped with a cryogenically cooled receiver containing an array of 62 polarization-sensitive bolometers. The focal plane contains pixels at two different frequency bands, 100 GHz and 150 GHz, with angular resolutions of 5 arcmin and 3.5 arcmin, respectively. The high angular resolution allows observation of CMB temperature and polarization anisotropies over a wide range of scales. The instrument commenced operation in early 2005 and collected science data during three successive Austral winter seasons of observation., Comment: 23 pages, author list and text updated to reflect published version
- Published
- 2008
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96. Second and third season QUaD CMB temperature and polarization power spectra
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QUaD collaboration, Pryke, C., Ade, P., Bock, J., Bowden, M., Brown, M. L., Cahill, G., Castro, P. G., Church, S., Culverhouse, T., Friedman, R., Ganga, K., Gear, W. K., Gupta, S., Hinderks, J., Kovac, J., Lange, A. E., Leitch, E., Melhuish, S. J., Memari, Y., Murphy, J. A., Orlando, A., Schwarz, R., O'Sullivan, C., Piccirillo, L., Rajguru, N., Rusholme, B., Taylor, A. N., Thompson, K. L., Turner, A. H., Wu, E. Y. S., and Zemcov, M.
- Subjects
Astrophysics - Abstract
We report results from the second and third seasons of observation with the QUaD experiment. Angular power spectra of the Cosmic Microwave Background are derived for both temperature and polarization at both 100 GHz and 150 GHz, and as cross frequency spectra. All spectra are subjected to an extensive set of jackknife tests to probe for possible systematic contamination. For the implemented data cuts and processing technique such contamination is undetectable. We analyze the difference map formed between the 100 and 150 GHz bands and find no evidence of foreground contamination in polarization. The spectra are then combined to form a single set of results which are shown to be consistent with the prevailing LCDM model. The sensitivity of the polarization results is considerably better than that of any previous experiment -- for the first time multiple acoustic peaks are detected in the E-mode power spectrum at high significance., Comment: 24 pages, 23 figures, updated to reflect published version
- Published
- 2008
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- View/download PDF
97. Delayed-choice test of complementarity with single photons
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Jacques, Vincent, Wu, E., Grosshans, Frédéric, Treussart, François, Grangier, Philippe, Aspect, Alain, and Roch, Jean-François
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Quantum Physics - Abstract
We report an experimental test of complementarity using clock-triggered single-photon pulses emitted by an individual N-V color center in a diamond nanocrystal. The single photons are sent into a Mach-Zehnder interferometer with an output beamsplitter of adjustable reflection coefficient R. In addition, the choice of introducing or removing this beamsplitter is random and relativistically space-like separated from the entering of the photon inside the interferometer, as required for the Wheeler's delayed-choice regime. Each set value of R allows us to observe interference with visibility V and to obtain incomplete which-path information characterized by the distinguishability D. The measured values of V and D are found to obey the complementarity relation V^2 + D^2 =< 1.
- Published
- 2008
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- View/download PDF
98. Thermochemical Property Measurements of FLiNaK and FLiBe in FY 2020
- Author
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Lichtenstein, T., primary, Rose, M., additional, Krueger, J., additional, Wu, E., additional, and Williamson, M., additional
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- 2022
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99. Wheeler's delayed-choice thought experiment: Experimental realization and theoretical analysis
- Author
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Jacques, Vincent, Wu, E., Grosshans, Frédéric, Treussart, François, Aspect, Alain, Grangier, Philippe, and Roch, Jean-François
- Subjects
Quantum Physics - Abstract
Wheeler has strikingly illustrated the wave-particle duality by the delayed-choice thought experiment, in which the configuration of a 2-path interferometer is chosen after a single-photon light-pulsed has entered it. We present a quantitative theoretical analysis of an experimental realization of Wheeler's proposal.
- Published
- 2007
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- View/download PDF
100. Room temperature triggered single-photon source in the near infrared
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Wu, E., Rabeau, James, Roger, Gérard, Treussart, François, Zeng, Heping, Grangier, Philippe, Prawer, Steven, and Roch, Jean-François
- Subjects
Quantum Physics - Abstract
We report the realization of a solid-state triggered single-photon source with narrow emission in the near infrared at room temperature. It is based on the photoluminescence of a single nickel-nitrogen NE8 colour centre in a chemical vapour deposited diamond nanocrystal. Stable single-photon emission has been observed in the photoluminescence under both continuous-wave and pulsed excitations. The realization of this source represents a step forward in the application of diamond-based single-photon sources to Quantum Key Distribution (QKD) under practical operating conditions., Comment: 10 pages
- Published
- 2007
- Full Text
- View/download PDF
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