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5,646 results on '"Wright, Michael"'

52. Fatally flawed

Author

Wright, Michael and Greenhill, Marc

Published
2017

65. Simulation of the effects of vibration in CMB experiments

Author

Wright, Michael, Dickinson, Mark, and Piccirillo, Lucio

Subjects
FEA, cryogenics, vibration, CMB, QUBIC
Abstract

Since the first discovery of the CMB, observations of its properties have been made in greater and greater detail due to their incredible usefulness to cosmology. Of particular interest to modern cosmology is the polarisation of the CMB, and in 2008 the QUBIC collaboration was founded as one of many ideas to measure this polarisation. However, measuring the polarisation of the CMB is an exceptionally challenging task, and many possible sources of error exist which could affect the validity of the results of these experiments. One such problem is the effect of the vibration of the instrument caused by its own mechanical movements. This thesis explores the possible effects of this vibration, using the simulation software MODAL, developed by the university of Maynooth and the QUBIC sim- ulation pipeline, written by the QUBIC collaboration team. The effect of vibra- tions on the CMB cross polarisation spectra is identified in this work. This thesis also includes research into measuring vibrations in a cryostat at the University of Manchester, using the technique of laser self mixing. The magni- tude of these vibrations is recorded.

Published
2023

95. Commanding an Army Field Support Battalion

Author

Wright, Michael T., LtCol

Subjects
ARMY - Corps, Divisions, etc - United States - Organization, ROLES AND MISSIONS - Army - United States, LOGISTICS - Army - United States, COMMANDING OFFICERS - Lessons Learned, MANAGEMENT, MILITARY
Abstract

illus

Published
2012

96. Position fixing with cold atom gravity gradiometers

Author

Phillips, Alexander M., Wright, Michael J., Riou, Isabelle, Maddox, Stephen, Maskell, Simon, and Ralph, Jason F.

Subjects
Quantum Physics
Abstract

This paper proposes a position fixing method for autonomous navigation using partial gravity gradient solutions from cold atom interferometers. Cold atom quantum sensors can provide ultra-precise measurements of inertial quantities, such as acceleration and rotation rates. However, we investigate the use of pairs of cold atom interferometers to measure the local gravity gradient and to provide position information by referencing these measurements against a suitable database. Simulating the motion of a vehicle, we use partial gravity gradient measurements to reduce the positional drift associated with inertial navigation systems. Using standard open source global gravity databases, we show stable navigation solutions for trajectories of over 1000km., Comment: 10 pages, 6 figures

Published
2022
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98. Identifying phenotypic expansions for congenital diaphragmatic hernia plus (CDH+) using DECIPHER data.

Author

Hardcastle, Amy, Berry, Aliska, Campbell, Ian, Zhao, Xiaonan, Liu, Pengfei, Gerard, Amanda, Rosenfeld, Jill, Sisoudiya, Saumya, Hernandez-Garcia, Andres, Loddo, Sara, Di Tommaso, Silvia, Novelli, Antonio, Dentici, Maria, Capolino, Rossella, Digilio, Maria, Graziani, Ludovico, Rustad, Cecilie, Neas, Katherine, Ferrero, Giovanni, Brusco, Alfredo, Di Gregorio, Eleonora, Wellesley, Diana, Beneteau, Claire, Joubert, Madeleine, Van Den Bogaert, Kris, Boogaerts, Anneleen, McMullan, Dominic, Dean, John, Giuffrida, Maria, Bernardini, Laura, Varghese, Vinod, Shannon, Nora, Harrison, Rachel, Lam, Wayne, McKee, Shane, Turnpenny, Peter, Cole, Trevor, Morton, Jenny, Eason, Jacqueline, Hall, Rebecca, Wright, Michael, Horridge, Karen, Shaw, Chad, Chung, Wendy, Scott, Daryl, and Jones, Marilyn

Subjects
CREBBP, DECIPHER database, SMARCA4, UBA2, USP9X, congenital diaphragmatic hernia, Animals, DNA Copy Number Variations, Diaphragm, Hernias, Diaphragmatic, Congenital, Mice
Abstract

Congenital diaphragmatic hernia (CDH) can occur in isolation or in conjunction with other birth defects (CDH+). A molecular etiology can only be identified in a subset of CDH cases. This is due, in part, to an incomplete understanding of the genes that contribute to diaphragm development. Here, we used clinical and molecular data from 36 individuals with CDH+ who are cataloged in the DECIPHER database to identify genes that may play a role in diaphragm development and to discover new phenotypic expansions. Among this group, we identified individuals who carried putatively deleterious sequence or copy number variants affecting CREBBP, SMARCA4, UBA2, and USP9X. The role of these genes in diaphragm development was supported by their expression in the developing mouse diaphragm, their similarity to known CDH genes using data from a previously published and validated machine learning algorithm, and/or the presence of CDH in other individuals with their associated genetic disorders. Our results demonstrate how data from DECIPHER, and other public databases, can be used to identify new phenotypic expansions and suggest that CREBBP, SMARCA4, UBA2, and USP9X play a role in diaphragm development.

Published
2022

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