68 results on '"Wenche S. Borgnakke"'
Search Results
52. The multi-center randomized controlled trial (RCT) published by the journal of the American Medical Association (JAMA) on the effect of periodontal therapy on glycated hemoglobin (HbA1c) has fundamental problems
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Phoebus N. Madianos, P. Mark Bartold, Thomas Kocher, Steven Offenbacher, Thomas E. Van Dyke, Gary C. Armitage, Maurizio S. Tonetti, Iain L. C. Chapple, Niklaus P. Lang, William V. Giannobile, Wenche S. Borgnakke, Paul I. Eke, Robert J. Genco, Philip M. Preshaw, Francesco D'Aiuto, Mariano Sanz, Shinya Murakami, Kenneth S. Kornman, Jørgen Slots, Amin ur Rahman, Fusanori Nishimura, University of Zurich, and Borgnakke, Wenche S
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Male ,medicine.medical_specialty ,Periodontal treatment ,Glycated Hemoglobin A ,Clinical Trials and Supportive Activities ,MEDLINE ,Dentistry ,610 Medicine & health ,Article ,law.invention ,Bibliographic information ,Root Planing ,Diabetes Complications ,chemistry.chemical_compound ,10068 Clinic of Reconstructive Dentistry ,Randomized controlled trial ,law ,Clinical Research ,medicine ,Diabetes Mellitus ,Humans ,Dental/Oral and Craniofacial Disease ,Trial registration ,General Dentistry ,Glycated Hemoglobin ,business.industry ,Diabetes ,Evidence-based medicine ,medicine.disease ,Chronic periodontitis ,3500 General Dentistry ,Good Health and Well Being ,chemistry ,Diabetes Mellitus, Type 2 ,Family medicine ,Chronic Periodontitis ,Dental Scaling ,Female ,Glycated hemoglobin ,business ,Type 2 - Abstract
SUBJECT: Participants had type 2 diabetes, were on stable medication regimens, had HbA1c levels between 7% and
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- 2014
53. DETERMINING DENTAL CHECKUP FREQUENCY
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Linda V. Nyquist, Wenche S. Borgnakke, W. Paul Lang, George W. Taylor, Marilyn W. Woolfolk, and David L. Ronis
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Adult ,Male ,Michigan ,Chi-Square Distribution ,Adolescent ,Urban Population ,business.industry ,Suburban Population ,MEDLINE ,Dental Prophylaxis ,Dentistry ,Middle Aged ,Interviews as Topic ,stomatognathic diseases ,Logistic Models ,Socioeconomic Factors ,stomatognathic system ,Humans ,Medicine ,Female ,Dental Care ,business ,General Dentistry ,Chi-squared distribution - Abstract
The authors assessed the dental checkup frequency of adults living in the Detroit tricounty area and identified demographic, access and subjective factors associated with visits to a dentist made not because of a dental problem.Data are from a 1994 probability-based sample of adults who were interviewed and received an in-home oral examination. The authors used the variables of age, sex, education level, income level, dental insurance status, usual place for care, objective measures of oral health, and subjective assessments of health, pain and dental anxiety to predict the frequency of dental checkups.The authors found that differences in dental checkup behavior were related to demographics, access to dental care, subjective ratings of oral and general health and other self-assessments, and clinical parameters of oral health. In multiple logistic regression analysis considering all variables simultaneously, sex, income, having a usual place for care and level of dental care anxiety were found to be associated with having dental checkups. The authors determined the statistical significance level at P.05.A total of 69.7 percent of the study population reported having had a dental checkup at least once a year in the past five years. The authors found that four factors associated with infrequent dental checkups: being male, having lower income levels, not having a usual place for care and being anxious about receiving dental care.Dental health professionals should consider the correlates of dental checkup frequency identified in this study and the usefulness of proposed strategies to increase and sustain regular preventive visitation patterns in their own patient populations.
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- 1999
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54. WITHDRAWN: The randomized controlled trial (RCT) published by the Journal of the American Medical Association (JAMA) on the impact of periodontal therapy on glycated hemoglobin (HbA1c) has fundamental flaws
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Mariano Sanz, Niklaus P. Lang, Philip M. Preshaw, Amin ur Rahman, Kenneth S. Kornman, Maurizio S. Tonetti, Iain L. C. Chapple, Wenche S. Borgnakke, Shinya Murakami, Panos N. Papapanou, Jørgen Slots, Francesco D'Aiuto, Gary C. Armitage, Robert J. Genco, P. Mark Bartold, Paul I. Eke, Thomas E. Van Dyke, Phoebus N. Madianos, and William V. Giannobile
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Dental practice ,Gerontology ,medicine.medical_specialty ,business.industry ,law.invention ,chemistry.chemical_compound ,chemistry ,Randomized controlled trial ,law ,Internal medicine ,Medicine ,Glycated hemoglobin ,business ,General Dentistry - Abstract
Please cite this article as: Borgnakke WS, Madianos PN, Chapple ILC, Murakami S, Genco RJ, Papapanou PN, Armitage G, Preshaw PM, Bartold PM, Rahman Au, D’Aiuto F, Sanz M, Eke PI, Slots J, Giannobile WV, Tonetti MS, Kornman KS, Van Dyke TE, Lang NP, WITHDRAWN: The randomized controlled trial (RCT) published by the Journal of the American Medical Association (JAMA) on the impact of periodontal therapy on glycated hemoglobin (HbA1c) has fundamental flaws, The Journal of Evidence-Based Dental Practice (2014), doi: 10.1016/j.jebdp.2014.01.011.
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- 2014
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55. Evaluation and Use of an Index of Oral Health Status
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Marilyn W. Woolfolk, George W. Taylor, Linda V. Nyquist, W. Paul Lang, David L. Ronis, and Wenche S. Borgnakke
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Male ,Gerontology ,Michigan ,Self-Assessment ,Multivariate statistics ,Multivariate analysis ,Health Behavior ,Oral Health ,Health Status Indicators ,Medicine ,Dental Care ,Aged, 80 and over ,education.field_of_study ,Smoking ,Age Factors ,Middle Aged ,Evaluation Studies as Topic ,Educational Status ,Regression Analysis ,Female ,Adult ,medicine.medical_specialty ,Adolescent ,Population ,Tooth Loss ,Humans ,education ,General Dentistry ,Socioeconomic status ,Periodontal Diseases ,Aged ,Demography ,Probability ,Analysis of Variance ,DMF Index ,Medicaid ,business.industry ,Public health ,Racial Groups ,Public Health, Environmental and Occupational Health ,Reproducibility of Results ,United States ,stomatognathic diseases ,Social Class ,Multivariate Analysis ,Composite index ,business ,Biomedical sciences - Abstract
Objectives: The goals of this investigation were (1) to evaluate the Oral Health Status Index in relation to demographic characteristics, socioeconomic status, and preventive behaviors of an adult population; and (2) to understand how individual index components performed as indicators of oral health status com- pared to the composite index. Methods: The Oral Health Status Index (OHSI) was used on a probability sample of adults, aged 18-93 years, living in the Detroit tricounty area. Data were collected on 509 subjects via in-home dental examina- tions. Bivariate and multivariate analyses were used to compare the OHSl and its components, including decayed, missing, and replaced teeth, free ends, and moderate and severe periodontal disease measures. Results: The mean OHSI score for subjects was 77.3 (SE= 1.83) with a range of -8.0 to 700.0. In regression analyses, OHSl scores were positively correlated with subjects' education level, self-rated oral health scores, and frequency of dental checkups and negatively correlated with age, nonwhite race, and smoking. Of the index components, missing teeth performed well as an indicator of oral health status. Missing teeth were positively correlated with age, nonwhite race, and smoking and negatively correlated with education level, self-rated oral health, and use of Medicaid. About 53 percent of variance in OHSl scores was explained by the multivariate models, compared to 46 percent for missing teeth. Conclusions: Choosing an indicator of oral health status likely will depend upon the characteristics of the population to be studied. As a composite measure of oral health status, the OHSlperformed acceptably; however, missing teeth, an index component, also worked well. Continued evaluation of the OHSl is warranted. (J Public Health Dent 1 997;57(4):233-42)
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- 1997
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56. Periodontitis: the canary in the coal mine
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Wenche S, Borgnakke, Michael, Glick, and Robert J, Genco
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Causality ,Diabetes Complications ,Pregnancy ,Risk Factors ,Health Status ,Pregnancy Outcome ,Humans ,Female ,Oral Health ,Atherosclerosis ,Periodontitis - Published
- 2013
57. Effect of periodontal disease on diabetes: systematic review of epidemiologic observational evidence
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Wenche S. Borgnakke, George W. Taylor, Pekka Ylöstalo, and Robert J. Genco
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medicine.medical_specialty ,Cross-sectional study ,business.industry ,Incidence (epidemiology) ,MEDLINE ,medicine.disease ,Surgery ,Gestational diabetes ,Diabetes Complications ,Cross-Sectional Studies ,Diabetes mellitus ,Epidemiology ,Gingival Diseases ,medicine ,Diabetes Mellitus ,Periodontics ,Humans ,Generalizability theory ,Intensive care medicine ,Adverse effect ,business ,Periodontal Diseases - Abstract
Background: Periodontal disease and diabetes mellitus are common, chronic diseases worldwide. Epidemiologic and biologic evidence suggest periodontal disease may affect diabetes. Objective: To systematically review non-experimental, epidemiologic evidence for effects of periodontal disease on diabetes control, complications and incidence. Data sources: Electronic bibliographic databases, supplemented by hand searches of recent and future issues of relevant journals. Study eligibility criteria and participants: Longitudinal and cross-sectional epidemiologic, non-interventional studies that permit determination of directionality of observed effects were included. Study appraisal and synthesis methods: Four reviewers evaluated pair-wise each study. Review findings regarding study results and quality were summarized in tables by topic, using the PRISMA Statement for reporting and the NewcastleOttawa System for quality assessment, respectively. From 2246 citations identified and available abstracts screened, 114 full-text reports were assessed and 17 included in the review. Results: A small body of evidence supports significant, adverse effects of periodontal disease on glycaemic control, diabetes complications, and development of type 2 (and possibly gestational) diabetes. Limitations: There were only a limited number of eligible studies, several of which included small sample sizes. Exposure and outcome parameters varied, and the generalizability of their results was limited. Conclusions and implications of key findings: Current evidence suggests that periodontal disease adversely affects diabetes outcomes, and that further longitudinal studies are warranted.
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- 2012
58. Dental visits among adult Hispanics--BRFSS 1999 and 2006
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Paul I, Eke, Freder, Jaramillo, Gina O, Thornton-Evans, and Wenche S, Borgnakke
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Adult ,Humans ,Hispanic or Latino ,Dental Health Services - Abstract
This study examined and compared utilization of dental services by adult U.S. Hispanics 18 years and older in the years 1999 and 2006.Dental utilization data collected by telephone interviews by the state-based Behavioral Risk Factor Surveillance System (BRFSS) were analyzed.In 2006, the state mean and median prevalence of adult Hispanics with dental visits during the past year were 56.2 percent and 62.1 percent, respectively, and had not changed significantly since 1999. In 40 states, utilization was well below the national prevalence of 70.3 percent. Frequency of dental visits was significantly higher among females and those with higher income ($50,000), higher education, nonsmokers, and persons having medical health insurance.Findings from this study suggest that barriers to utilization of dental services among Hispanic adults exist in most states and may contribute to existing oral health disparities. The magnitude of this problem may increase in the future with the expansion of the U.S. Hispanic population.
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- 2011
59. Dental visits among adult Hispanics - BRFSS 1999 and 2006
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Gina Thornton-Evans, Freder Jaramillo, Wenche S. Borgnakke, and Paul I. Eke
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medicine.medical_specialty ,Behavioral Risk Factor Surveillance System ,business.industry ,Public health ,Public Health, Environmental and Occupational Health ,Oral health ,Dental care ,stomatognathic diseases ,Environmental health ,Medicine ,Hispanic population ,Medical health ,business ,General Dentistry ,Biomedical sciences - Abstract
Objectives: This study examined and compared utilization of dental services by adult US Hispanics 18 years and older in the years 1999 and 2006. Methods: Dental utilization data collected by telephone interviews by the state-based Behavioral Risk Factor Surveillance System (BRFSS) were analyzed. Results: In 2006, the state mean and median prevalence of adult Hispanics with dental visits during the past year were 56.2 percent and 62.1 percent, respectively, and had not changed significantly since 1999. In 40 states, utilization was well below the national prevalence of 70.3 percent. Frequency of dental visits was significantly higher among females and those with higher income (>$50,000), higher education, nonsmokers, and persons having medical health insurance. Conclusions: Findings from this study suggest that barriers to utilization of dental services among Hispanic adults exist in most states and may contribute to existing oral health disparities. The magnitude of this problem may increase in the future with the expansion of the US Hispanic population.
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- 2011
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60. Salivary glucose levels are unable to predict oral candidiasis or monitor diabetes
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Wenche S. Borgnakke
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medicine.medical_specialty ,business.industry ,Dental research ,Dentistry ,medicine.disease ,Bibliographic information ,stomatognathic diseases ,Salivary glucose ,Carriage ,Diabetes control ,Internal medicine ,Diabetes mellitus ,Medicine ,business ,General Dentistry - Abstract
Article Title and Bibliographic Information Salivary glucose levels and oral candidal carriage in type II diabetics. Sashikumar R, Kannan R. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;109(5):706-11. Reviewer Wenche S. Borgnakke, DDS, MPH, PhD Purpose/Question (1) What is the relationship between salivary glucose and oral candida carriage? and (2) Can salivary glucose levels be used to monitor diabetes control? Source of Funding The Chennai Dental Research Foundation, India Type of Study/Design Cross-sectional Level of Evidence Level 2: Limited-quality, patient-oriented evidence Strength of Recommendation Grade Not applicable
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- 2010
61. Treatment of Established Complications: Periodontal Disease
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George W. Taylor and Wenche S. Borgnakke
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Periodontal disease ,business.industry ,Dentistry ,Medicine ,business - Published
- 2010
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62. Periodontal disease: associations with diabetes, glycemic control and complications
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Wenche S. Borgnakke and George W. Taylor
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Blood Glucose ,Glycation End Products, Advanced ,medicine.medical_specialty ,MEDLINE ,Dentistry ,Diabetes Complications ,Periodontal disease ,Internal medicine ,Diabetes mellitus ,Epidemiology ,Diabetes Mellitus ,Medicine ,Humans ,Adverse effect ,General Dentistry ,Periodontal Diseases ,Glycemic ,business.industry ,Incidence (epidemiology) ,medicine.disease ,Oxidative Stress ,Glucose ,Otorhinolaryngology ,Observational study ,Inflammation Mediators ,business - Abstract
Objective: This report reviews the evidence for adverse effects of diabetes on periodontal health and periodontal disease on glycemic control and complications of diabetes. Design: MEDLINE search of the English language literature identified primary research reports published on (a) relationships between diabetes and periodontal diseases since 2000 and (b) effects of periodontal infection on glycemic control and diabetes complications since 1960. Results: Observational studies provided consistent evidence of greater prevalence, severity, extent, or progression of at least one manifestation of periodontal disease in 13/17 reports reviewed. Treatment and longitudinal observational studies provided evidence to support periodontal infection having an adverse effect on glycemic control, although not all investigations reported an improvement in glycemic control after periodontal treatment. Additionally, evidence from three observational studies supported periodontal disease increasing the risk for diabetes complications and no published reports refuted the findings. Conclusion: The evidence reviewed supports diabetes having an adverse effect on periodontal health and periodontal infection having an adverse effect on glycemic control and incidence of diabetes complications. Further rigorous study is necessary to establish unequivocally that treating periodontal infections can contribute to glycemic control management and to the reduction of the burden of diabetes complications.
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- 2008
63. Diabetes, periodontal diseases, dental caries, and tooth loss: a review of the literature
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George W, Taylor, Michael C, Manz, and Wenche S, Borgnakke
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Blood Glucose ,Tooth Loss ,Diabetes Mellitus, Type 2 ,Risk Factors ,Humans ,Dental Caries ,Periodontal Diseases - Abstract
Diabetes mellitus, is a common chronic disease, and its prevalence in the United States, particularly type 2 diabetes, is increasing. Complications associated with diabetes impose a heavy burden on many people, especially among certain minority populations. Periodontal diseases, dental caries, and tooth loss also are common conditions in the United States, but their prevalence is generally decreasing. Nevertheless, among important subgroups of the population, particularly certain minority and economically disadvantaged groups, there is a disproportionately higher burden of periodontal diseases, dental caries, and tooth loss. This article reviews the post-1960 English-language literature on the relationship between diabetes and oral health, specifically focusing on periodontal disease, dental caries, and tooth loss. Substantial evidence exists to support the role of diabetes and poorer glycemic control as important risk factors for periodontal disease. Additionally, the evidence provides support for viewing the relationship between diabetes and periodontal diseases as bidirectional. However, additional research is necessary to firmly establish that treating periodontal infections can contribute to glycemic control management and possibly to the reduction of type 2 diabetes complications. The literature does not describe a consistent relationship between type 2 diabetes and dental caries. It reports increased, decreased, and similar caries experiences between those with and without diabetes. This review suggests that currently there is insufficient evidence to determine whether a relationship between diabetes and risk for coronal or root caries exists. Most of the reviewed studies reported greater tooth loss in people with diabetes. However, the differences were slight and not significant in several of the reports. Furthermore, this review of the association between diabetes and tooth loss reveals that valid population-based evidence generalizable to the US population is sparse. Further investigations of the association of diabetes with dental caries and tooth loss are warranted. If adverse effects of diabetes on dental caries and/or tooth loss are substantiated, the results of such studies would help design intervention studies to prevent or reduce the occurrence of dental caries and tooth loss in people with diabetes. These results also may affect existing clinical practice protocols and promote new public policy related to diabetes.
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- 2005
64. Prospective evaluation of the systemic inflammatory marker C-reactive protein in patients with end-stage periodontitis getting teeth replaced with dental implants: a pilot investigation
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Amin Ur, Rahman, Saqib, Rashid, Rizwana, Noon, Zeerak S, Samuel, Bing, Lu, Wenche S, Borgnakke, and Ray C, Williams
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Dental Implants ,Male ,Analysis of Variance ,Time Factors ,Dental Implantation, Endosseous ,Pilot Projects ,Middle Aged ,C-Reactive Protein ,Tooth Extraction ,Humans ,Female ,Prospective Studies ,Periodontitis ,Aged - Abstract
Serum C-reactive protein (CRP) has been shown to be a risk predictor for cardiovascular disease. Periodontal treatment reduces elevated CRP levels. The aim of this pilot investigation was to evaluate if dental implants placed after extractions in patients with end-stage periodontitis affect the serum CRP levels.Serum CRP levels in 10 subjects with end-stage periodontitis were measured prior to tooth extraction and placement of dental implants, and at 3-month intervals for a year post-operatively. Univariate repeated measures analysis of variance was used to estimate and test the changes in CRP levels over time.Mean CRP levels decreased significantly following tooth extraction and replacement with dental implants from 3.45 to 1.55 mg/dl after 12 months (P0.01). Six-, 9-, and 12-month post-implant placement mean CRP values were statistically significantly different from the mean pre-operative CRP value (P0.01).The pilot data suggest that extraction of advanced periodontally involved teeth and their replacement with dental implants lead to a decrease in CRP levels, and dental implant placement does not change the lowered CRP levels over a 12-month period.
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- 2005
65. Hemoglobin A1cLevels Among Patients With Diabetes Receiving Nonsurgical Periodontal Treatment
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Iain L. C. Chapple, Robert J. Genco, and Wenche S. Borgnakke
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medicine.medical_specialty ,business.industry ,MEDLINE ,General Medicine ,Type 2 diabetes ,medicine.disease ,Chronic periodontitis ,law.invention ,Scaling and root planing ,Randomized controlled trial ,law ,Internal medicine ,Diabetes mellitus ,medicine ,Physical therapy ,Adverse effect ,business ,Glycemic - Abstract
The report by Dr Engebretson and colleagues1 explored the effect of nonsurgical periodontal therapy (scaling and root planing) on glycemic control in persons with type 2 diabetes and chronic periodontitis. Given the high global prevalence of both diseases, the adverse effect of periodontal infection on blood glucose levels and diabetes complications,2 and the improvements in levels of HbA1c following clinically effective periodontal therapy reported in meta-analyses,3 the results of this multicenter RCT require careful review to ensure that the conclusions drawn are supported by the data. We identified important problems with the study design, execution, data interpretation, and reporting that we think render the conclusions inappropriate.
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- 2014
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66. Preventive oral health behaviors among African-Americans and whites in Detroit
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David L. Ronis, Wenche S. Borgnakke, Cathy L. Antonakos, and W. Paul Lang
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Gerontology ,Adult ,Male ,Toothbrushing ,medicine.medical_specialty ,Michigan ,Adolescent ,Health Behavior ,Oral health ,Family income ,Plaque control ,Health Services Accessibility ,White People ,Dental Devices, Home Care ,Interviews as Topic ,Medicine ,Humans ,Dental Care ,General Dentistry ,Socioeconomic status ,Chi-Square Distribution ,business.industry ,Medicaid ,Oral health education ,Public health ,Public Health, Environmental and Occupational Health ,Middle Aged ,United States ,Black or African American ,stomatognathic diseases ,Social Class ,Tooth Diseases ,Multivariate Analysis ,Income ,Educational Status ,Oral health care ,Female ,business ,Attitude to Health ,Demography - Abstract
Objective: This study compared the preventive oral health behaviors of African-Americans and whites. Methods: Face-to-face interviews were conducted with a probability sample of 384 African-American and 358 white adults living in the greater Detroit area. Questions focused on brushing, flossing, and dental visits. Results: More than 95 percent of both groups reported brushing daily; however, whites were more likely to brush all teeth, including parts that do not show. Frequency of flossing did not differ between groups. African-Americans, however, were less likely to floss all of their teeth. Whites were more likely than African-Americans to get dental check-ups at least once a year and much less likely to indicate they had never had a dental check-up. African-Americans tended to have less education and lower family income than whites and were more likely than whites to have Medicaid. Race differences in brushing thoroughness and annual check-ups were greatly reduced when income, education, and insurance were controlled statistically. Conclusion: African-Americans are less likely than whites to brush thoroughly, floss thoroughly, and get dental check-ups. These differences are partly traceable to differences in socioeconomic status and access to professional oral health care.
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- 1999
67. Taking Out All Teeth and Replacing Them With Dentures That Rest on Implants in People With Type 2 Diabetes
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Rahman & Rahman Dental Surgeons, Lahore, Pakistan and Wenche S. Borgnakke DDS MPH PhD, Adjunct Clinical Assistant Professor
- Published
- 2018
68. Oral Health and Diabetes
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Borgnakke WS, Genco RJ, Eke PI, Taylor GW, Cowie CC, Casagrande SS, Menke A, Cissell MA, Eberhardt MS, Meigs JB, Gregg EW, Knowler WC, Barrett-Connor E, Becker DJ, Brancati FL, Boyko EJ, Herman WH, Howard BV, Narayan KMV, Rewers M, and Fradkin JE
- Abstract
The vast majority of the U.S. adult population suffers from periodontal diseases, as about 90% suffer from the reversible form, gingivitis, whereas almost 50% of adults age ≥30 years are affected by periodontitis, which is the chronic periodontal breakdown of both soft and hard tissues that support the teeth. Diabetes prevalence is assuming epidemic proportions with 30.2 million or 12.2% of the U.S. adult population age ≥18 years having diabetes in 2015, of whom about one-quarter are unaware of their diabetes; an additional one-third (84.1 million) have prediabetes, of whom about 90% are unaware. Due to the great prevalence of both diseases, it is important for health care professionals and lay people alike to be aware of both periodontal diseases and diabetes and their two-way interactions in which they mutually and adversely affect each other to understand how to prevent, treat, and manage both diseases. Since periodontitis and diabetes share the same risk factors, any improvement in a risk factor should beneficially affect both conditions. This concept is shown by a decrease in the level of inflammation upon nonsurgical periodontal treatment, which improves both periodontal health in individuals with type 2 diabetes and those without diabetes, as well as glycemic control in type 2 diabetes and in people with prediabetes. Gingivitis is a reversible inflammation of the soft tissues surrounding the teeth in response to dental plaque, whereas periodontitis is a chronic, inflammatory disease that in response to dental plaque causes breakdown of the soft and hard tissues surrounding the teeth in susceptible individuals. This destruction often occurs without any pain or other symptoms. Nonetheless, if left untreated, it can lead to loosening of the tooth and eventually to its total loss, with adverse effects on nutrition, self-esteem, and function. Moreover, the number of teeth lost is strongly associated with atherosclerotic cardiovascular disease, and advanced tooth loss, especially edentulism (loss of all teeth), is associated with premature all-cause mortality. Periodontitis causes local and systemic inflammatory responses that lead to development or worsening of hyperglycemia and hence contribute to increased blood glucose levels in healthy individuals; development of prediabetes, type 2 diabetes, and gestational diabetes; decreased glycemic control in overt diabetes; and worsening of diabetes complications. Diabetes is also a chronic, inflammation-related metabolic disease diagnosed by hyperglycemia. Such elevated blood glucose levels negatively impact the inflammatory response to dental plaque, leading to more severe gingivitis and periodontitis. Hence, periodontitis and diabetes mutually and adversely affect each other. Importantly, the risk factors are largely identical for these two diseases, so when identifying and improving risk factors related to one of the two diseases, the other could be present and its severity lessened. Such improvements could consist of quitting smoking, decreasing intake of added sugar, reducing any inflammation, and getting sufficient sleep at healthy times per the circadian rhythm. Routine, nonsurgical, periodontal treatment (“deep cleaning”) that can be performed by dental health care professionals in general dental practice or in periodontists’ specialty offices—together with proper home oral hygiene care—can lead to improved glycemic control in type 2 diabetes. Hyperglycemia can also contribute to impaired healing of lesions around the apex (tip) of the teeth with chronic infection and inflammation persisting in the jaw bone. Extraction of teeth that suffer from chronic periodontitis or periapical periodontitis leads to decreased levels of inflammatory biomarkers. Moreover, diabetes and the use of diabetes medication can lead to dry mouth, which contributes to development of caries, periodontitis, and thrush (candidiasis). Diabetic neuropathy can lead to burning mouth syndrome (glossodynia) and taste impairment (dysgeusia) and may be involved in trigeminal nerve pain and temporomandibular joint disorders. Both periodontitis and diabetes lead to potentially severely diminished quality of life. Nonetheless, people with diabetes have fewer dental visits than their peers without diabetes. It is important for both dental and medical care providers to keep in mind the possible coexistence of periodontitis and dysglycemia (hyperglycemia), as both diseases negatively affect each other. Proper, mutual referral is essential, as both diseases can be improved, if the informed providers collaborate in a patient-centered, interprofessional team approach in the interest of the best possible oral and systemic health for their mutual patients. Therefore, it may make both medical and financial sense to include the attainment of a healthy mouth in diabetes management, as well as screening for diabetes in the dental office, with the potential for substantial decreases in the burden of both human disease and suffering, as well as financial costs, to the benefit of the individuals, their caregivers, and society overall.
- Published
- 2018
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