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544 results on '"Ward, Wendy E."'

80. Maternal Consumption of Hesperidin and Naringin Flavanones Exerts Transient Effects to Tibia Bone Structure in Female CD-1 Offspring

Author

Sacco, Sandra M., Saint, Caitlin, LeBlanc, Paul J., and Ward, Wendy E.

Subjects
musculoskeletal diseases, Citrus, mice, Bone Development, Lumbar Vertebrae, naringin, Tibia, Plant Extracts, Hesperidin, flavanones, X-Ray Microtomography, musculoskeletal system, Article, Animals, Female, structure, Femur
Abstract

Hesperidin (HSP) and naringin (NAR), flavanones rich in citrus fruits, support skeletal integrity in adult and aging rodent models. This study determined whether maternal consumption of HSP and NAR favorably programs bone development, resulting in higher bone mineral density (BMD) and greater structure and biomechanical strength (i.e., peak load) in female offspring. Female CD-1 mice were fed a control diet or a HSP + NAR diet five weeks before pregnancy and throughout pregnancy and lactation. At weaning, female offspring were fed a control diet until six months of age. The structure and BMD of the proximal tibia were measured longitudinally using in vivo micro-computed tomography at 2, 4, and 6 months of age. The trabecular bone structure at two and four months and the trabecular BMD at four months were compromised at the proximal tibia in mice exposed to HSP and NAR compared to the control diet (p < 0.001). At six months of age, these differences in trabecular structure and BMD at the proximal tibia had disappeared. At 6 months of age, the tibia midpoint peak load, BMD, structure, and the peak load of lumbar vertebrae and femurs were similar (p > 0.05) between the HSP + NAR and control groups. In conclusion, maternal consumption of HSP and NAR does not enhance bone development in female CD-1 offspring.

Published
2017

81. Patients undergoing periodontal procedures commonly use dietary supplements: A consideration in the design of intervention trials.

Author

Beaudette, Jennifer R., Fritz, Peter C., Sullivan, Philip J., Piccini, Assunta, and Ward, Wendy E.

Subjects
DIETARY supplements, VITAMIN D
Abstract

Objective: Diet and dietary supplement use are associated with periodontal health while a cause and effect relationship is less clear. Although associations with specific nutrients and supplements suggest a potential benefit to healing of periodontal tissues after periodontal procedures, this study determined if patients undergoing periodontal surgery currently take dietary supplements to gage whether patients may accept use of such supplements as a potential intervention. Materials and methods: Patients who were undergoing implant placement or soft tissue graft surgery completed a questionnaire indicating any dietary supplements they consumed. Patient demographics, such as age, sex, and smoking status, were gathered from patients' charting records. Results: Data on dietary supplement usage were collected from 221 patients. More than half (64.7%) the population surveyed reported using one or more dietary supplements. The most commonly used dietary supplements were vitamin D (31%), multivitamin (28%), and B‐complex (17.2%). Females were more likely to be taking calcium, vitamin B12, and magnesium than males. Adults, aged 51 years and older, were more likely to be taking dietary supplements than their younger counterparts. They were also more likely to be taking four or more supplements than those under the age of 50 years. There was no association between supplement use and sex, but when the number of different supplements being used was assessed, females were more likely than males to be taking four or more different supplements. Conclusions: The majority of the study population is already taking dietary supplements as part of their routine. Based on this study, future studies to determine if supplement usage, potentially at levels higher than current levels of intake, can be used to maintain or promote periodontal health seem highly feasible. [ABSTRACT FROM AUTHOR]

Published
2021
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88. Influence of longitudinal radiation exposure from microcomputed tomography scanning on skeletal muscle function and metabolic activity in female CD-1 mice

Author

Mikhaeil, John S., primary, Sacco, Sandra M., additional, Saint, Caitlin, additional, Gittings, William, additional, Bunda, Jordan, additional, Giles, Cameron R., additional, Andrew Fajardo, Val, additional, Vandenboom, Rene, additional, Ward, Wendy E., additional, and LeBlanc, Paul J., additional

Published
2017
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96. Prebiotics: Not only for gut health?

Author

Zanatta, Carly A.R. and Ward, Wendy E.

Subjects
FERMENTED foods, DIETARY fiber, PREBIOTICS, GUT microbiome, ORAL health, INFLAMMATION, BLOOD sugar, DIETARY supplements, HUMAN microbiota, WEIGHT loss, BACTERIA
Published
2020

97. Polycystic ovarian syndrome and periodontal disease: Is there a link?

Author

Young, Hannah E. and Ward, Wendy E.

Subjects
BALDNESS, POLYCYSTIC ovary syndrome, MENSTRUATION disorders, FOLLICLE-stimulating hormone, OVARIAN cysts, ACNE, HYPERTRICHOSIS, ANDROGENS, MENSTRUAL cycle, PERIODONTAL disease, AMENORRHEA, LUTEIN, ESTROGEN, INFERTILITY, HYPERANDROGENISM, PHENOTYPES
Published
2020

98. Supporting Healthy Gums with the 3G Rule.

Author

Madanat, Sara and Ward, Wendy E.

Subjects
AEROBIC exercises, ORAL hygiene, NUTRITION, ORAL health, TOOTH care & hygiene, DIET, GINGIVAL hyperplasia
Published
2023

99. The Ovariectomized Rat as a Model for Studying Alveolar Bone Loss in Postmenopausal Women

Author

Johnston, Bryan D. and Ward, Wendy E.

Subjects
Article Subject
Abstract

In postmenopausal women, reduced bone mineral density at the hip and spine is associated with an increased risk of tooth loss, possibly due to a loss of alveolar bone. In turn, having fewer natural teeth may lead to compromised food choices resulting in a poor diet that can contribute to chronic disease risk. The tight link between alveolar bone preservation, tooth retention, better nutritional status, and reduced risk of developing a chronic disease begins with the mitigation of postmenopausal bone loss. The ovariectomized rat, a widely used preclinical model for studying postmenopausal bone loss that mimics deterioration of bone tissue in the hip and spine, can also be used to study mineral and structural changes in alveolar bone to develop drug and/or dietary strategies aimed at tooth retention. This review discusses key findings from studies investigating mandible health and alveolar bone in the ovariectomized rat model. Considerations to maximize the benefits of this model are also included. These include the measurement techniques used, the age at ovariectomy, the duration that a rat is studied after ovariectomy and habitual diet consumed.

Published
2015
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