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1,353 results on '"Wang, Xiao-min"'

52. Effect of heat treatment on microstructure and mechanical properties of FeCrMnNiCox alloy

Author

LI He-qi, WANG Xiao-min, and ZENG Hong-yan

Subjects
fecrmnnicox, heat treatment temperature, morphology, mechanical property, Materials of engineering and construction. Mechanics of materials, TA401-492
Abstract

FeCrMnNiCo, FeCrMnNiCo0.5 and FeCrMnNi alloys were prepared by vacuum melting and casting technology after metal powders was mixed by planetary ball mill. The effects of heat treatment temperature on the microstructures, tensile properties and hardness of three kinds of multi-principal alloys were studied by means of metallographic microscope, scanning electron microscopy (SEM), hardness tester and universal tensile testing machine. The results show that the hardness of FeCrMnNi alloy after heat treatment at 900 ℃ is the highest and the maximum hardness is 380HV. The plasticity of FeCrMnNiCo0.5 alloy is the largest after heat treatment at 700 ℃, and its elongation after fracture is 54.7%. At the same heat treatment temperature, with the increase of Co content, the alloys’ structure is changed from dendritic to honeycomb, and the alloys’ tensile strength is decreased. The hardness of the same alloy is increased with the increase of heat treatment temperature, which may be related to the increase of precipitates after heat treatment, but its tensile strength remains unchanged.

Published
2020
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69. Preface

Author

Zhang, Qiang, primary, Tao, Xin-yong, additional, Li, Feng, additional, Wu, Ding-cai, additional, and Wang, Xiao-min, additional

Published
2023
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84. Chinese guidelines for treatment of adult primary immune thrombocytopenia

Author

Liu, Xin-guang, Bai, Xiao-chuan, Chen, Fang-ping, Cheng, Yun-feng, Dai, Ke-sheng, Fang, Mei-yun, Feng, Jian-Ming, Gong, Yu-ping, Guo, Tao, Guo, Xin-hong, Han, Yue, Hong, Luo-jia, Hu, Yu, Hua, Bao-lai, Huang, Rui-bing, Li, Yan, Peng, Jun, Shu, Mi-mi, Sun, Jing, Sun, Pei-yan, Sun, Yu-qian, Wang, Chun-sen, Wang, Shu-jie, Wang, Xiao-min, Wu, Cong-ming, Wu, Wen-man, Yan, Zhen-yu, Yang, Feng-e, Yang, Lin-hua, Yang, Ren-Chi, Yang, Tong-hua, Ye, Xu, Zhang, Guang-sen, Zhang, Lei, Zheng, Chang-cheng, Zhou, Hu, Zhou, Min, Zhou, Rong-fu, Zhou, Ze-ping, Zhu, Hong-li, Zhu, Tie-nan, and Hou, Ming

Published
2018
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89. Supplemental Table S1 from MBD2 Ablation Impairs Lymphopoiesis and Impedes Progression and Maintenance of T-ALL

Author

Zhou, Mi, primary, Zhou, Kuangguo, primary, Cheng, Ling, primary, Chen, Xing, primary, Wang, Jue, primary, Wang, Xiao-Min, primary, Zhang, Yingchi, primary, Yu, Qilin, primary, Zhang, Shu, primary, Wang, Di, primary, Huang, Liang, primary, Huang, Mei, primary, Ma, Ding, primary, Cheng, Tao, primary, Wang, Cong-Yi, primary, Yuan, Weiping, primary, and Zhou, Jianfeng, primary

Published
2023
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90. Supplementary data 1 from MBD2 Ablation Impairs Lymphopoiesis and Impedes Progression and Maintenance of T-ALL

Author

Zhou, Mi, primary, Zhou, Kuangguo, primary, Cheng, Ling, primary, Chen, Xing, primary, Wang, Jue, primary, Wang, Xiao-Min, primary, Zhang, Yingchi, primary, Yu, Qilin, primary, Zhang, Shu, primary, Wang, Di, primary, Huang, Liang, primary, Huang, Mei, primary, Ma, Ding, primary, Cheng, Tao, primary, Wang, Cong-Yi, primary, Yuan, Weiping, primary, and Zhou, Jianfeng, primary

Published
2023
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91. Supplementary data 2 from MBD2 Ablation Impairs Lymphopoiesis and Impedes Progression and Maintenance of T-ALL

Author

Zhou, Mi, primary, Zhou, Kuangguo, primary, Cheng, Ling, primary, Chen, Xing, primary, Wang, Jue, primary, Wang, Xiao-Min, primary, Zhang, Yingchi, primary, Yu, Qilin, primary, Zhang, Shu, primary, Wang, Di, primary, Huang, Liang, primary, Huang, Mei, primary, Ma, Ding, primary, Cheng, Tao, primary, Wang, Cong-Yi, primary, Yuan, Weiping, primary, and Zhou, Jianfeng, primary

Published
2023
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95. S1PR1 regulates ovarian cancer cell senescence through the PDK1-LATS1/2-YAP pathway

Author

Tao, Yi Ping, Zhu, Heng Yan, Shi, Qian Yuan, Wang, Cai Xia, Hua, Yu Xin, Hu, Han Yin, Zhou, Qi Yin, Zhou, Zi Lu, Sun, Ying, Wang, Xiao Min, Wang, Yu, Zhang, Ya Ling, Guo, Yan Jun, Wang, Zi Ying, Che, Xuan, Xu, Chun Wei, Zhang, Xian Chao, Heger, Michal, Tao, Su Ping, Zheng, Xin, Xu, Ying, Ao, Lei, Liu, Ai Jun, Liu, Sheng Bing, Cheng, Shu Qun, Pan, Wei Wei, Tao, Yi Ping, Zhu, Heng Yan, Shi, Qian Yuan, Wang, Cai Xia, Hua, Yu Xin, Hu, Han Yin, Zhou, Qi Yin, Zhou, Zi Lu, Sun, Ying, Wang, Xiao Min, Wang, Yu, Zhang, Ya Ling, Guo, Yan Jun, Wang, Zi Ying, Che, Xuan, Xu, Chun Wei, Zhang, Xian Chao, Heger, Michal, Tao, Su Ping, Zheng, Xin, Xu, Ying, Ao, Lei, Liu, Ai Jun, Liu, Sheng Bing, Cheng, Shu Qun, and Pan, Wei Wei

Abstract

Cell senescence deters the activation of various oncogenes. Induction of senescence is, therefore, a potentially effective strategy to interfere with vital processes in tumor cells. Sphingosine-1-phosphate receptor 1 (S1PR1) has been implicated in various cancer types, including ovarian cancer. The mechanism by which S1PR1 regulates ovarian cancer cell senescence is currently elusive. In this study, we demonstrate that S1PR1 was highly expressed in human ovarian cancer tissues and cell lines. S1PR1 deletion inhibited the proliferation and migration of ovarian cancer cells. S1PR1 deletion promoted ovarian cancer cell senescence and sensitized ovarian cancer cells to cisplatin chemotherapy. Exposure of ovarian cancer cells to sphingosine-1-phosphate (S1P) increased the expression of 3-phosphatidylinositol-dependent protein kinase 1 (PDK1), decreased the expression of large tumor suppressor 1/2 (LATS1/2), and induced phosphorylation of Yes-associated protein (p-YAP). Opposite results were obtained in S1PR1 knockout cells following pharmacological inhibition. After silencing LATS1/2 in S1PR1-deficient ovarian cancer cells, senescence was suppressed and S1PR1 expression was increased concomitantly with YAP expression. Transcriptional regulation of S1PR1 by YAP was confirmed by chromatin immunoprecipitation. Accordingly, the S1PR1-PDK1-LATS1/2-YAP pathway regulates ovarian cancer cell senescence and does so through a YAP-mediated feedback loop. S1PR1 constitutes a druggable target for the induction of senescence in ovarian cancer cells. Pharmacological intervention in the S1PR1-PDK1-LATS1/2-YAP signaling axis may augment the efficacy of standard chemotherapy.

Published
2023

96. S1PR1 regulates ovarian cancer cell senescence through the PDK1-LATS1/2-YAP pathway

Author

Sub Membrane Biochemistry & Biophysics, Pharmaceutics, Tao, Yi Ping, Zhu, Heng Yan, Shi, Qian Yuan, Wang, Cai Xia, Hua, Yu Xin, Hu, Han Yin, Zhou, Qi Yin, Zhou, Zi Lu, Sun, Ying, Wang, Xiao Min, Wang, Yu, Zhang, Ya Ling, Guo, Yan Jun, Wang, Zi Ying, Che, Xuan, Xu, Chun Wei, Zhang, Xian Chao, Heger, Michal, Tao, Su Ping, Zheng, Xin, Xu, Ying, Ao, Lei, Liu, Ai Jun, Liu, Sheng Bing, Cheng, Shu Qun, Pan, Wei Wei, Sub Membrane Biochemistry & Biophysics, Pharmaceutics, Tao, Yi Ping, Zhu, Heng Yan, Shi, Qian Yuan, Wang, Cai Xia, Hua, Yu Xin, Hu, Han Yin, Zhou, Qi Yin, Zhou, Zi Lu, Sun, Ying, Wang, Xiao Min, Wang, Yu, Zhang, Ya Ling, Guo, Yan Jun, Wang, Zi Ying, Che, Xuan, Xu, Chun Wei, Zhang, Xian Chao, Heger, Michal, Tao, Su Ping, Zheng, Xin, Xu, Ying, Ao, Lei, Liu, Ai Jun, Liu, Sheng Bing, Cheng, Shu Qun, and Pan, Wei Wei

Published
2023

100. The dynamic contact of a viscoelastic coated half-plane under a rigid flat punch.

Author

Wang, Xiao-Min, Ke, Liao-Liang, and Wang, Yue-Sheng

Subjects
*CAUCHY integrals, *INTEGRAL transforms, *FOURIER integrals, *VISCOELASTIC materials, *FOURIER transforms, *SINGULAR integrals
Abstract

This paper investigates the dynamic contact response of a viscoelastic coated half-plane under a forced rigid punch. This punch, acting on the coating surface, is subjected to a concentrated vertical harmonic force. The coating and half-plane are assumed as viscoelastic materials which can be described by the linear hysteretic damping model. Using the Fourier integral transform technique and the asymptotic method, the dynamic contact problem is reduced to a Cauchy singular integral equation. By using appropriate numerical method, the dynamic contact stress and vertical impedance for the flat punch are calculated. It is found that the dynamic contact behaviors are not only affected by the external excitation frequency but also dependent on the material properties of the coated half-plane. [ABSTRACT FROM AUTHOR]

Published
2023
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