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322 results on '"Wang, Jinju"'

55. Ischemia-induced brain damage is enhanced in human renin and angiotensinogen double-transgenic mice

Author

Chen, Shuzhen, Li, Guangze, Zhang, Wenfeng, Wang, Jinju, Sigmund, Curt D., Olson, James E., and Chen, Yanfang

Subjects
Angiotensin -- Physiological aspects, Angiotensin -- Research, Brain damage -- Risk factors, Brain damage -- Research, Mice -- Usage, Mice -- Models, Renin -- Physiological aspects, Renin -- Research, Biological sciences
Abstract

To investigate the role of brain angiotensin II (ANG II) in the pathogenesis of injury following ischemic stroke, mice overexpressing renin and angiotensinogen (R + A +) and their wild-type control animals (R - A -) were used for experimental ischemia studies. Focal brain ischemia was induced by middle cerebral artery occlusion (MCAO). The severity of ischemic injury was determined by measuring neurological deficits and histological damage at 24 and 48 h after MCAO, respectively. To exclude the influence of blood pressure and local collateral blood flow, brain slices were used for oxygen and glucose deprivation (OGD) studies. The severity of OGD-induced damage was determined by measuring indicators of tissue swelling and cell death, the intensity of the intrinsic optical signal (IOS), and the number of propidium iodide (PI) staining cells, respectively. Results showed 1) R + A + mice showed higher neurological deficit score (3.8 [+ or -] 0.5 and 2.5 [+ or -] 0.3 for R + A + and R - A -, respectively, P < 0.01) and larger infarct volume (22.2 [+ or -] 1.6% and 14.1 [+ or -] 1.2% for R + A + and R - A -, respectively, P < 0.01); 2) The R + A + brain slices showed more severe tissue swelling and cell death in the cortex (IOS: 140 [+ or -] 6% and 114 [+ or -] 10%; PI: 139 [+ or -] 20 cells/field and 39 [+ or -] 9 cells/field for R + A + and R - A -, respectively, P < 0.01); 3) treatment with losartan (20 [micro]mol/1) abolished OGD-induced exaggeration of cell injury seen in R + A + mice. The data indicate that activation of ANG II/[AT.sub.1] signaling is harmful to brain exposed to ischemia. [AT.sub.1] receptor; mouse; losartan; middle cerebral artery doi: 10.1152/ajpregu.91040.2008.

Published
2009

77. LncRNA SNHG10 Facilitates Hepatocarcinogenesis and Metastasis by Modulating Its Homolog SCARNA13 via a Positive Feedback Loop

Author

Lan, Tian, primary, Yuan, Kefei, additional, Yan, Xiaokai, additional, Xu, Lin, additional, Liao, Haotian, additional, Hao, Xiangyong, additional, Wang, Jinju, additional, Liu, Hong, additional, Chen, Xiangzheng, additional, Xie, Kunlin, additional, Li, Jiaxin, additional, Liao, Mingheng, additional, Huang, Jiwei, additional, Zeng, Yong, additional, and Wu, Hong, additional

Published
2019
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84. Microvesicles‐mediated communication between endothelial cells modulates, endothelial survival, and angiogenic function via transferring of miR‐125a‐5p

Author

Pan, Qunwen, primary, Ma, Chunlian, additional, Wang, Yan, additional, Wang, Jinju, additional, Zheng, Jieyi, additional, Du, Donghui, additional, Liao, Xiaorong, additional, Chen, Yusen, additional, Chen, Yanfang, additional, Bihl, Ji, additional, Chen, Can, additional, Yang, Yi, additional, and Ma, Xiaotong, additional

Published
2018
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95. Synergistic antitumor activity of the combination of salubrinal and rapamycin against human cholangiocarcinoma cells

Author

Zhao, Xiaofang, primary, Zhang, Chunyan, additional, Zhou, Hong, additional, Xiao, Bin, additional, Cheng, Ying, additional, Wang, Jinju, additional, Yao, Fuli, additional, Duan, Chunyan, additional, Chen, Run, additional, Liu, Youping, additional, Feng, Chunhong, additional, Li, Hong, additional, Li, Jing, additional, and Dai, Rongyang, additional

Published
2016
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99. Narrative Function of the Description of Daily Meals in A Dream of Red Mansions.

Author

Wang Jinju and Zhang Yujie

Abstract

The narrative of meals in A Dream of Red Mansions has been a topic of concern to critics. Among the numerous descriptions about daily meals in the novel, some are simple, acting as narrative techniques such as introduction, development, transition and closure, and some are more specific, functioning as narrative techniques and narrative contents at the same time. As narrative contents, they provide ideological meaning and literary value. And as narrative techniques, they play important roles in structuring, plotting and characterization. By studying the narrative of meals, we could see the difference between chapters 1 -- 80 and the rest of the chapters. Cao Xueqin consciously narrates and describes meals as an important aspect of the family's daily life, which, on the one hand, reflects essential aspects of the noble family, and on the other hand, reveals the exploration and innovation of A Dream of Red Mansions in the narration of fiction. [ABSTRACT FROM AUTHOR]

Published
2018

100. Physicochemical analysis of Mozzarella cheese produced and developed by the novel EPS‐producing strain <italic>Lactobacillus kefiranofaciens</italic> ZW3.

Author

Rehman, Rizwan‐ur, Wang, Yanping, Wang, Jinju, and Geng, Weitao

Subjects
MOZZARELLA cheese, LACTOBACILLUS, MICROSTRUCTURE, CHEESE texture, MICROBIAL exopolysaccharides, KEFIR
Abstract

A novel exopolysaccharide‐producing strain Lactobacillus kefiranofaciens ZW3, isolated from Tibetan kefir grain, was used as an adjunct strain to compare the physicochemical, textural and structural properties of Mozzarella cheese also made with market‐available starter cultures and acetic acid‐made cheese. Stretchability, meltability and fat leakage attributes were improved in ZW3‐made cheese. Textural analysis revealed that stain ZW3 improved the hardness and chewiness of the Mozzarella cheese but had little impact on the cohesiveness, elasticity and resilience of Mozzarella cheese. Microstructure studies indicated that ZW3‐made Mozzarella cheese is more filamentous, ropy and compact when compared to the controls cheeses. [ABSTRACT FROM AUTHOR]

Published
2018
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