Search

Your search keyword '"Wang, Hui-Juan"' showing total 621 results
Start Over Author "Wang, Hui-Juan"
621 results on '"Wang, Hui-Juan"'

52. Case report: A compound heterozygous mutations in ARSA associated with adult-onset metachromatic leukodystrophy

Author

Wang, Bing-lei, Lu, Fen-lei, Sun, Yu-chen, and Wang, Hui-juan

Subjects
Neurology, Neurology (clinical)
Abstract

Metachromatic Leukodystrophy (MLD) is a rare autosomal recessive disease, which is caused by mutations in the arylsulfatase A (ARSA) gene. The ARSA gene is located on chromosome 22q13, containing eight exons. According to the age of onset, MLD can be divided into late infantile type, juvenile type, and adult type. Adult MLD has an insidious onset after the age of 16 years. Additionally, intellectual as well as behavioral changes, such as memory deficits or emotional instability, are commonly the first presenting symptoms. There is a study that reported an adult-onset MLD manifested cognitive impairment progressively due to compound heterozygous mutations of NM_000487: c.[185_186dupCA], p.(Asp63GlnfsTer18), and NM_000487: c.[154G>T], p.(Gly172Cys), rs74315271 in the ARSA gene, finding that the c.[154G>T], p.(Gly172Cys) is a novel missense mutation. Brain magnetic resonance imaging (MRI) revealed symmetrical demyelination of white matter. The activity of ARSA enzymatic in leukocytes decreased. Nerve conduction studies displayed that evidence of polyneuropathy was superimposed upon diffuse, uniform demyelinating, and sensorimotor polyneuropathy. Family genes revealed that each family member carried one of two heterozygous mutant genes. She has been discharged and is currently being followed up. This study found a compound heterozygous mutation in the ARSA gene associated with MLD and identified a novel missense mutation NM_000487: c.[154G>T], p.(Gly172Cys), rs74315271. This will provide a critical clue for prenatal diagnosis of the offspring in this family, and expand the mutation spectrum of MLD-related ARSA.

Published
2022

56. Cu(OAc)2‐Mediated Synthesis of Fullerodihydropyridine‐3‐ones via the Reaction of [60]Fullerene with β‐Substituted Ethylamines in the Absence or Presence of Arylacetaldehydes†.

Author

Liu, Xiu‐Shan, Wang, Hui‐Juan, Wu, Fei‐Lun, Huo, Jing‐Wen, Wang, Xing‐Yu, Li, Fa‐Bao, Sun, Rui, Liu, Li, and Liu, Chao‐Yang

Subjects
*FULLERENE derivatives, *COPPER, *ETHYLAMINES, *SOLAR cells, *SCISSION (Chemistry)
Abstract

Comprehensive Summary: A series of unreported fullerodihydropyridine‐3‐ones were synthesized as a new family of fullerene derivatives in moderate to good yields by a simple one‐step reaction of [60]fullerene with cheap and readily available β‐substituted ethylamines in the absence or presence of arylacetaldehydes under the assistance of Cu(OAc)2. The in situ generation of arylacetaldehydes by the C—N bond cleavage of arylethylamines avoided their complex synthesis in advance and realized the preparation of fullerodihydropyridine‐3‐ones with structural and functional diversities, which may have promising applications in perovskite solar cells to improve the performance of photovoltaic devices due to the existence of a large π‐conjugated system on the dihydropyridine‐3‐one ring. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

57. Cu(OAc)2‐Mediated Synthesis of Fullerodihydropyridine‐3‐ones via the Reaction of [60]Fullerene with β‐Substituted Ethylamines in the Absence or Presence of Arylacetaldehydes†.

Author

Liu, Xiu‐Shan, Wang, Hui‐Juan, Wu, Fei‐Lun, Huo, Jing‐Wen, Wang, Xing‐Yu, Li, Fa‐Bao, Sun, Rui, Liu, Li, and Liu, Chao‐Yang

Subjects
FULLERENE derivatives, COPPER, ETHYLAMINES, SOLAR cells, SCISSION (Chemistry)
Abstract

Comprehensive Summary: A series of unreported fullerodihydropyridine‐3‐ones were synthesized as a new family of fullerene derivatives in moderate to good yields by a simple one‐step reaction of [60]fullerene with cheap and readily available β‐substituted ethylamines in the absence or presence of arylacetaldehydes under the assistance of Cu(OAc)2. The in situ generation of arylacetaldehydes by the C—N bond cleavage of arylethylamines avoided their complex synthesis in advance and realized the preparation of fullerodihydropyridine‐3‐ones with structural and functional diversities, which may have promising applications in perovskite solar cells to improve the performance of photovoltaic devices due to the existence of a large π‐conjugated system on the dihydropyridine‐3‐one ring. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

63. Long-Term Prognostic Factors in Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A 15-Year Multicenter Retrospective Study

Author

Liao, Qian-Qian, primary, Ren, Ya-Fei, additional, Zhu, Ke-Wei, additional, Qin, Dong, additional, Mo, Yan-Ju, additional, Cong, Shan, additional, Wu, Juan, additional, Wang, Chun-Ying, additional, Cui, Xiao-Jiao, additional, Xu, Hong-Zhen, additional, Guo, Lin-Zheng, additional, Zhang, You-Yan, additional, Song, Hai-Xia, additional, Zhang, Wei, additional, Yang, Zhe, additional, Tang, Yan-Feng, additional, Li, Zhuo-Jun, additional, Xie, Zhou-Ni, additional, Li, Li-Mei, additional, Wang, Hui-Juan, additional, Zhou, Meng-Meng, additional, Wei, Fang-Ning, additional, Chen, Peng, additional, and Shi, Yu-Hong, additional

Published
2022
Full Text
View/download PDF

67. Concentrations, seasonal trends, sources, health risk and subchronic toxicity to the respiratory and immune system of PAHs in PM2.5 in Xi'an.

Author

Wang, Xiang-ni, Wang, Hui-juan, Ma, Yan, Liu, Jin-ren, Hao, Yue, Ma, Cai-qin, Liu, Na, Cui, Yi-xin, Shi, Xing-min, Gong, Fu-liang, and Wu, Xi-li

Subjects
*LUNGS, *RESPIRATORY organs, *IMMUNE system, *POLYCYCLIC aromatic hydrocarbons, *PATHOLOGICAL physiology, *SEASONS
Abstract

PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) have been proved to be hazardous to health. Previous studies have focused on the distribution and sources of PAHs, whereas there is little knowledge of the damage to organs. Here we sought to investigate the pollution level and seasonal variation characteristics of PAHs in PM2.5 in Xi'an and assess the health risk, to establish a PAHs exposure model, and investigate the toxicological effects of PAHs on the respiratory and immune functions. A sub-chronic exposure model of PAHs was established by inhalation. The pathological changes of lung tissues were observed with a light microscope. Inflammatory reactions in alveolar lavage fluid were determined using the corresponding kit. The levels of interleukin-6 (IL-6) and interleukin-8 (IL-8) were detected with enzyme linked immunosorbent assay (ELISA) kit; the proliferation of lymphocytes in spleen was detected with methyl tetrazolium (MTT); DNA immune damage was determined with DNA gel electrophoresis. The results showed that (1) the total concentration of 16 PAHs ranged from 41.1 to 387 ng/m3, with a mean value of 170 ng/m3, and the concentration of PAHs in PM2.5 was higher in winter than in other seasons. (2) The sources of PAHs in the atmosphere of Xi'an urban area were mainly coal combustion, and the equivalent carcinogenic concentration of PAHs in PM2.5 was 3.9 ng/m3. (3) Foreign body granuloma formation and inflammatory cell damage were observed in the lungs of rats infected with toxin; the levels of reactive oxygen species (ROS) and mobile device assistant (MDA) increased while nitric oxide synthase (NOS) decreased with the increase of dose; the expression levels of IL-6 and IL-8 elevated with the increase of toxin dose, showing an obvious dose-effect relationship; the level of PAHs damage to cells showed a dose-effect relationship. Sub-chronic exposure to PAHs could cause sustained inflammatory injury to the organism. Measures should be taken to counter the problems of PAHs in PM2.5 in Xi'an and relevant health promotion strategies should be developed. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

75. Long-Term Prognosis Factors in Patients with ANCA-Associated Vasculitis

Author

Liao, Qian-Qian, primary, Ren, Ya-Fei, additional, Zhu, Ke-Wei, additional, Qin, Dong, additional, Mo, Yan-Ju, additional, Cong, Shan, additional, Wu, Juan, additional, Wang, Chun-Ying, additional, Cui, Xiao-Jiao, additional, Xu, Hong-Zhen, additional, Guo, Lin-Zheng, additional, Zhang, You-Yan, additional, Song, Hai-Xia, additional, Zhang, Wei, additional, Yang, Zhe, additional, Tang, Yan-Feng, additional, Li, Zhuo-Jun, additional, Xie, Zhou-Ni, additional, Li, Li-Mei, additional, Wang, Hui-Juan, additional, Zhou, Meng-Meng, additional, Wei, Fang-Ning, additional, Chen, Peng, additional, and Shi, Yu-Hong, additional

Published
2022
Full Text
View/download PDF

81. Highly Enhanced Chloride Adsorption Mediates Efficient Neutral CO2Electroreduction over a Dual-Phase Copper Catalyst

Author

Yang, Peng-Peng, Zhang, Xiao-Long, Liu, Pei, Kelly, Daniel J., Niu, Zhuang-Zhuang, Kong, Yan, Shi, Lei, Zheng, Ya-Rong, Fan, Ming-Hui, Wang, Hui-Juan, and Gao, Min-Rui

Abstract

Electrocatalytic carbon dioxide reduction (CO2R) in neutral electrolytes can mitigate the energy and carbon losses caused by carbonate formation but often experiences unsatisfied multicarbon selectivity and reaction rates because of the kinetic limitation to the critical carbon monoxide (CO)–CO coupling step. Here, we describe that a dual-phase copper-based catalyst with abundant Cu(I) sites at the amorphous–nanocrystalline interfaces, which is electrochemically robust in reducing environments, can enhance chloride-specific adsorption and consequently mediate local *CO coverage for improved CO–CO coupling kinetics. Using this catalyst design strategy, we demonstrate efficient multicarbon production from CO2R in a neutral potassium chloride electrolyte (pH ∼6.6) with a high Faradaic efficiency of 81% and a partial current density of 322 milliamperes per square centimeter. This catalyst is stable after 45 h of operation at current densities relevant to commercial CO2electrolysis (300 mA per square centimeter).

Published
2023
Full Text
View/download PDF

82. Three cases of antibody-LGI1 limbic encephalitis and review of literature

Author

Wang Bing-Lei, Wang Hui-Juan, Shen Jian-Hua, Yue Zan, Bian Xin, Li Yan, and Zheng Jiahua

Subjects
Male, 0301 basic medicine, 03 medical and health sciences, Autoimmune Diseases of the Nervous System, 0302 clinical medicine, Limbic Encephalitis, medicine, Humans, Autoantibodies, Autoimmune encephalitis, biology, business.industry, General Neuroscience, Limbic encephalitis, Intracellular Signaling Peptides and Proteins, Proteins, General Medicine, Middle Aged, medicine.disease, Immune therapy, body regions, 030104 developmental biology, nervous system, Immunology, biology.protein, Female, Antibody, business, 030217 neurology & neurosurgery
Abstract

Antibody-LGI1 limbic encephalitis (LGI1-Ab LE) is an anti-neuronal surface antigen-related autoimmune encephalitis. we report three cases of LGI1-Ab LE, describe the characteristics of clinical manifestation, course of evolution, imaging manifestation and treatment outcomes.Data from patients diagnosed with LGI1-Ab LE in the Second Hospital, Hebei Medical University, from June 2016 to July 2017, were retrospectively collected and analyzed. We followed up the patients for 90 days.Two of the three patients were females, the average age of onset is 53 years old. Epilepsy is the most common clinical manifestations, and one of patients developed faciobrachial dystonic seizures (FBDS), which was recently described as a characteristic feature of LGI1-Ab LE. All patients had cognitive impairment in different degrees and abnormal signal of hippocampus in cranial MRI. All serum LGI1 antibodies were positive, whereas one LGI1 antibodies of CSF were negative. All patients accepted first-line immune therapy and had a good outcome.LGI1-Ab LE, which is an autoimmune disease, is rare clinically and mostly nonparaneoplastic. We suggest that LGI1-Ab LE be considered in any patient with acute or subacute onset, cognitive dysfunction , various types of seizures, accompanied by mental disorders and hyponatremia, MR showed the involvement of the limbic system. It is necessary to have LE-related antibodies tested. Early immunotherapy can significantly improve the patient's overall prognosis. At the same time, we should also pay attention to the possibility of potential tumors.

Published
2019

87. Analysis of the 1 And 2 States of λ And ξ with QCD sum rules

Author

Wang, Zhi-Gang and Wang, Hui-Juan

Abstract

In this article, we study the ground states and the first radial excited states of the flavor antitriplet heavy baryon states $\Lambda_Q$ and $\Lambda_Q$ with the spin-parity $\Lambda_Q$ by carrying out operator product expansion up to vacuum condensates of dimension $\Lambda_Q$ in a consistent way. We observe for the first time that the higher dimensional vacuum condensates play an important role, and obtain very stable QCD sum rules with variations of the Borel parameters for the heavy baryon states. The predicted masses $\Lambda_Q$ , $\Lambda_Q$ , and $\Lambda_Q$ for the first radial excited states $\Lambda_Q$ , $\Lambda_Q$ , and $\Lambda_Q$ , respectively, are in excellent agreement with the experimental data and support assigning $\Lambda_Q$ , $\Lambda_Q$ , and $\Lambda_Q$ to be the first radial excited states of $\Lambda_Q$ , $\Lambda_Q$ , and $\Lambda_Q$ , respectively. The predicted mass $\Lambda_Q$ for $\Lambda_Q$ can be confirmed using experimental data in the future.

Published
2021

88. Large-Area Crystalline Zeolitic Imidazolate Framework Thin Films

Author

Chen, Zhi, Wang, Rui, Ma, Tao, Wang, Jin-Long, Duan, Yu, Dai, Zhi-Zhan, Xu, Jie, Wang, Hui-Juan, Yuan, Jiayin, Jiang, Hai-Long, Yin, Yue-Wei, Li, Xiao-Guang, Gao, Min-Rui, Yu, Shu-Hong, Chen, Zhi, Wang, Rui, Ma, Tao, Wang, Jin-Long, Duan, Yu, Dai, Zhi-Zhan, Xu, Jie, Wang, Hui-Juan, Yuan, Jiayin, Jiang, Hai-Long, Yin, Yue-Wei, Li, Xiao-Guang, Gao, Min-Rui, and Yu, Shu-Hong

Abstract

We report that continuous MOF films with highly controlled thickness (from 44 to 5100 nm) can be deposited over length scales greater than 80 centimeters by a facile, fast, and cost-effective spray-coating method. Such success relies on our discovery of unprecedented perfectly dispersed colloidal solutions consisting of amorphous MOF nanoparticles, which we adopted as precursors that readily converted to the crystalline films upon low-temperature in situ heating. The colloidal solutions allow for the fabrication of compact and uniform MOF films on a great deal of substrates such as fluorine-doped tin oxide, glass, SiO2, Al2O3, Si, Cu, and even flexible polycarbonate, widening their technological applications where substrates are essential. Despite the present work focuses on the fabrication of uniform cobalt-(2-methylimidazole)2 and zinc-(2-methylimidazole)2 films, our findings mark a great possibility in producing other high-quality MOF thin films on a large scale.

Published
2021
Full Text
View/download PDF

91. Large‐Area Crystalline Zeolitic Imidazolate Framework Thin Films

Author

Chen, Zhi, primary, Wang, Rui, additional, Ma, Tao, additional, Wang, Jin‐Long, additional, Duan, Yu, additional, Dai, Zhi‐Zhan, additional, Xu, Jie, additional, Wang, Hui‐Juan, additional, Yuan, Jiayin, additional, Jiang, Hai‐Long, additional, Yin, Yue‐Wei, additional, Li, Xiao‐Guang, additional, Gao, Min‐Rui, additional, and Yu, Shu‐Hong, additional

Published
2021
Full Text
View/download PDF

98. Synergizing strong metal-support interactions and spatial confinement boosts dynamics of atomic nickel for hydrogenations

Author

Gu, Jian, primary, Jian, Minzhen, additional, Huang, Li, additional, Sun, Zhihu, additional, Pan, Yang, additional, Yang, Jiuzhong, additional, Wen, Wu, additional, Lin, Yue, additional, Wang, Hui-Juan, additional, Liu, Xinyu, additional, Wang, Leilei, additional, Shi, Xianxian, additional, Huang, Xiaohui, additional, Cao, Lina, additional, Chen, Si, additional, Zheng, Xu-Sheng, additional, Pan, Haibin, additional, Zhu, Junfa, additional, Wei, Shiqiang, additional, Li, Wei-Xue, additional, and Lu, Junling, additional

Published
2020
Full Text
View/download PDF

99. MET exon 14 skipping mutation, amplification and overexpression in pulmonary sarcomatoid carcinoma: A multi-center study

Author

Liu, Xue-wen, primary, Chen, Xin-ru, additional, Rong, Yu-ming, additional, Lyu, Ning, additional, Xu, Chun-wei, additional, Wang, Fang, additional, Sun, Wen-yong, additional, Fang, San-gao, additional, Yuan, Jing-ping, additional, Wang, Hui-juan, additional, Wang, Wen-xian, additional, Huang, Wen-bin, additional, Xu, Jian-ping, additional, Yue, Zhen-ying, additional, and Chen, Li-kun, additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results