51. Intravoxel incoherent motion MR imaging: comparison of diffusion and perfusion characteristics between nasopharyngeal carcinoma and post-chemoradiation fibrosis
- Author
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Victor Ho-Fun Lee, Xiao Li, Queenie Chan, Ka-On Lam, Vincent Lai, and Pek-Lan Khong
- Subjects
Adult ,Male ,medicine.medical_specialty ,Respiratory-Gated Imaging Techniques ,Adolescent ,Sensitivity and Specificity ,Diagnosis, Differential ,Motion ,Young Adult ,Imaging, Three-Dimensional ,Fibrosis ,Carcinoma ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Child ,Intravoxel incoherent motion ,Aged ,Aged, 80 and over ,Nasopharyngeal Carcinoma ,medicine.diagnostic_test ,business.industry ,Ultrasound ,Reproducibility of Results ,Magnetic resonance imaging ,Nasopharyngeal Neoplasms ,General Medicine ,Chemoradiotherapy ,Middle Aged ,medicine.disease ,Tumor Burden ,Radiation Pneumonitis ,Treatment Outcome ,Nasopharyngeal carcinoma ,Female ,Radiology ,business ,Perfusion ,Magnetic Resonance Angiography ,Diffusion MRI - Abstract
To compare the intravoxel incoherent motion (IVIM) diffusion and perfusion characteristics of nasopharyngeal carcinoma (NPC) and post-chemoradiation fibrosis to aid in their differentiation. Fifty-three (64 %) patients with newly diagnosed NPC and 30 (36 %) patients with biopsy-proven post-chemoradiation fibrosis were recruited into tumour and fibrosis groups respectively. Diffusion-weighted magnetic resonance (MR) imaging was performed using 13 b values (0–1,000 s/mm2). Their respective IVIM parameters (D, pure diffusion; f, perfusion fraction; D*, pseudodiffusion coefficient) were obtained. D and f were significantly lower in NPC (D = 0.752 ± 0.194 × 10-3 mm2/s, P
- Published
- 2013