852 results on '"Velkov, Tony"'
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52. Pharmacokinetics/pharmacodynamics of colistin and polymyxin B: are we there yet?
53. Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis
54. Mutations in the Vicinity of the IRAK3 Guanylate Cyclase Center Impact Its Subcellular Localization and Ability to Modulate Inflammatory Signaling in Immortalized Cell Lines
55. Cyclosporines: Biosynthesis and Beyond
56. The antihelminth drug rafoxanide reverses chromosomal-mediated colistin-resistance in Klebsiella pneumoniae.
57. Comparative Proteomics of Outer Membrane Vesicles from Polymyxin-Susceptible and Extremely Drug-Resistant Klebsiella pneumoniae
58. Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells
59. Critical Role of Position 10 Residue in the Polymyxin Antimicrobial Activity
60. Proof‐of‐concept for incorporating mechanistic insights from multi‐omics analyses of polymyxin B in combination with chloramphenicol against Klebsiella pneumoniae
61. The Role of HnrnpF/H as a Driver of Oligoteratozoospermia
62. A Novel Fe3o4-Doped Metal-Organic Framework for Chemo/Chemodynamic Synergistic Therapy Via Triggering Ferroptosis
63. Diversified Repertoire of Phage Defenses in Klebsiella pneumoniae: Bi-Directional Steering Effects Impacting Antibiotic Susceptibility
64. Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis
65. Cold adaptation generates mutations associated with the growth of influenza B vaccine viruses
66. Inhaled anti-infective chemotherapy for respiratory tract infections: Successes, challenges and the road ahead
67. Transcriptomic Mapping of Neurotoxicity Pathways in the Rat Brain in Response to Intraventricular Polymyxin B
68. Drug Repurposing Approaches towards Defeating Multidrug-Resistant Gram-Negative Pathogens: Novel Polymyxin/Non-Antibiotic Combinations
69. Diversified repertoire of phage defenses inKlebsiella pneumoniae: Bi-directional steering effects impacting antibiotic susceptibility
70. Polymyxins for CNS infections: Pharmacology and neurotoxicity
71. Colistin and Polymyxin B: Peas in a Pod, or Chalk and Cheese?
72. Novel Antimicrobial Peptides: Targeting Wound Infections Caused by ‘Superbugs’ Resistant to All Current Antibiotics
73. Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy
74. Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii
75. Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
76. An Intelligent Strategy with All-Atom Molecular Dynamics Simulations for the Design of Lipopeptides against Multidrug-Resistant Pseudomonas aeruginosa
77. Polymyxin dose tunes the evolutionary dynamics of resistance in multidrug-resistant Acinetobacter baumannii
78. Baicalein acts as a nephroprotectant that ameliorates colistin-induced nephrotoxicity by activating the antioxidant defence mechanism of the kidneys and down-regulating the inflammatory response
79. Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against Acinetobacter baumannii: A Metabolomic Study
80. Intraventricular Drug Delivery and Sampling for Pharmacokinetics and Pharmacodynamics Study
81. An Efficient Approach for the Design and Synthesis of Antimicrobial Peptide-Peptide Nucleic Acid Conjugates
82. Correlative proteomics identify the key roles of stress tolerance strategies in Acinetobacter baumannii in response to polymyxin and human macrophages
83. Additional file 2 of Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa
84. The Natural Product Curcumin as an Antibacterial Agent: Current Achievements and Problems
85. Polymyxin Induces Significant Transcriptomic Perturbations of Cellular Signalling Networks in Human Lung Epithelial Cells
86. p21 restricts influenza A virus by perturbing the viral polymerase complex and upregulating type I interferon signaling
87. Polymyxin causes cell envelope remodelling and stress responses in mcr-1-harbouring Escherichia coli
88. Pharmacokinetics of levobupivacaine following infant spinal anesthesia
89. Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two ‘old’ antibiotics—polymyxin B and chloramphenicol
90. Imaging the distribution of polymyxins in the kidney
91. The carbohydrate-binding promiscuity of Euonymus europaeus lectin is predicted to involve a single binding site
92. Post-ejaculatory changes in the metabolic status of rat spermatozoa as measured by GC-MS
93. Polymyxin-Induced Metabolic Perturbations in Human Lung Epithelial Cells
94. Insights Into Patient Variability During Ivacaftor-Lumacaftor Therapy in Cystic Fibrosis
95. A Precision Medicine Approach to Optimize Modulator Therapy for Rare CFTR Folding Mutants
96. Inhibition of Oxidative Stress and ALOX12 and NF-κB Pathways Contribute to the Protective Effect of Baicalein on Carbon Tetrachloride-Induced Acute Liver Injury
97. Polymyxins for the treatment of lower respiratory tract infections: lessons learned from the integration of clinical pharmacokinetic studies and clinical outcomes
98. A protocol for the combined sub-fractionation and delipidation of lipid binding proteins using hydrophobic interaction chromatography
99. Characterization of lipophilic drug binding to rat intestinal fatty acid binding protein
100. Synchrotron-Based X-Ray Fluorescence Microscopy Reveals Accumulation of Polymyxins in Single Human Alveolar Epithelial Cells
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