551 results on '"Velazquez, E"'
Search Results
52. Trypanosoma cruzi Discrete Typing Units in Chagas disease patients from endemic and non-endemic regions of Argentina
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CURA, C. I., LUCERO, R. H., BISIO, M., OSHIRO, E., FORMICHELLI, L. B., BURGOS, J. M., LEJONA, S., BRUSÉS, B. L., HERNÁNDEZ, D. O., SEVERINI, G. V., VELAZQUEZ, E., DUFFY, T., ANCHART, E., LATTES, R., ALTCHEH, J., FREILIJ, H., DIEZ, M., NAGEL, C., VIGLIANO, C., FAVALORO, L., FAVALORO, R. R., MERINO, D. E., SOSA-ESTANI, S., and SCHIJMAN, A. G.
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- 2012
53. P769Evaluation of mechanical dyssynchrony by cross-correlation analysis predicts long-term survival after cardiac resynchronization therapy
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Risum, N, Williams, E, Khouri, M, Jackson, K, Olsen, NT, Jons, C, Storm, KS, Velazquez, E J, Kisslo, J, and Sogaard, P
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- 2011
54. Impact of Tricuspid Valve Repair for Moderate Tricuspid Regurgitation at the Time of Left Ventricular Assist Device Implantation on the Occurrence of Right Heart Failure
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Barac, Y.D., primary, Bishawi, M., additional, Milano, C., additional, Schroder, J., additional, Daneshmand, M., additional, Hashmi, N., additional, Velazquez, E., additional, Rogers, J., additional, Patel, C., additional, and Nicoara, A., additional
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- 2020
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55. P1773 Cohort of HER2 positive breast cancer and subclinical cardiotoxicity by speckle tracking echocardiography. Does chemotherapy sequence matter?
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Guzman Ayon, A M, primary, Aceves Velazquez, E D, additional, Armengol Alonso, A, additional, and Vasquez Ortiz, Z Y, additional
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- 2020
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56. P1696 Intravascular leiomyomatosis with inferior vena cava and intracardiac extension, with severe obstruccion to the right ventricle.The fundamental role of transesophageal echocardiography
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Vasquez-Ortiz, Z Y, primary, Guzman Ayon, A, additional, Aceves Velazquez, E D, additional, Navarrete Garcia, J, additional, Hernandez-Reyes, P, additional, and Oseguera Moguel, J, additional
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- 2020
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57. P778 Evaluation of left auricular and ventricular subclinical function by strain imaging in a cohort of hereditary TTR + amyloidosis
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Aceves Velazquez, E D, primary, Guzman Ayon, A M, additional, Gonzalez Duarte, A, additional, and Vasquez Ortiz, Z Y, additional
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- 2020
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58. Departures from the protocol during conduct of a clinical trial: a pattern from the data record consistent with a learning curve
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Taekman, J M, Stafford-Smith, M, Velazquez, E J, Wright, M C, Phillips-Bute, B G, Pfeffer, M A, Sellers, M A, Pieper, K S, Newman, M F, Van de Werf, F, Diaz, R, Leimberger, J, and Califf, R M
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- 2010
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59. ZnO thin film as non-enzymatic glucose sensor in an alkaline solution
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Villasana-Ponce, G., primary, Chalé-Lara, F., additional, Olarte Villamizar, G., additional, Valaguez Velazquez, E., additional, Cruz-González, N., additional, Marquez Herrera, A., additional, and Zapata-Torres, M., additional
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- 2019
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60. PCI and CABG for Treating Stable Coronary Artery Disease JACC Review Topic of the Week
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Doenst, T, Haverich, A, Serruys, PWJC, Bonow, RO, Kappetein, Arie-Pieter, Falk, V, Velazquez, E, Diegeler, A, Sigusch, H, and Cardiothoracic Surgery
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- 2019
61. Antibacterial and free-radical scavenging activities of Sonoran propolis
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Velazquez, C., Navarro, M., Acosta, A., Angulo, A., Dominguez, Z., Robles, R., Robles-Zepeda, R., Lugo, E., Goycoolea, F. M., Velazquez, E. F., Astiazaran, H., and Hernandez, J.
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- 2007
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62. Polymorphisms in Adenosine Receptor Genes are Associated with Infarct Size in Patients with Ischemic Cardiomyopathy
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Tang, Z, Diamond, M A, Chen, J-M, Holly, T A, Bonow, R O, Dasgupta, A, Hyslop, T, Purzycki, A, Wagner, J, McNamara, D M, Kukulski, T, Wos, S, Velazquez, E J, Ardlie, K, and Feldman, A M
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- 2007
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63. A picture is worth 1,000 words
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Nifong-Velazquez, E.
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Sport-utility vehicles ,General interest ,Military and naval science - Abstract
The morning of Nov 28, 2005 started out like any other Monday morning in a small Alabama town. Even the weather said it was a Monday as it was a [...]
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- 2007
64. I've lived & learned
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Nifong-Velazquez, E.
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United States. Air Force -- Officials and employees ,United States. Air Force -- Safety and security measures ,Air pilots, Military -- Safety and security measures ,Air pilots, Military -- Personal narratives ,General interest ,Military and naval science - Abstract
Just 4 years ago I almost died ... several times. I guess you could say I was in my 'I'm invincible' phase. I was a divorced, single parent and wanted [...]
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- 2006
65. Blood glucose control for type I diabetes mellitus: A robust tracking H∞ problem
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Ruiz-Velázquez, E., Femat, R., and Campos-Delgado, D.U.
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- 2004
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66. CABG Improves Outcomes in Patients With Ischemic Cardiomyopathy: 10-Year Follow-Up of the STICH Trial
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Howlett, J, Stebbins, A, Petrie, M, Jhund, P, Castelvecchio, S, Cherniavsky, A, Sueta, C, Roy, A, Piña, I, Wurm, R, Drazner, M, Andersson, B, Batlle, C, Senni, M, Chrzanowski, L, Merkely, B, Carson, P, Desvigne-Nickens, P, Lee, K, Velazquez, E, Al-Khalidi, H, STICH Trial, I, Howlett JG, Stebbins A, Petrie MC, Jhund PS, Castelvecchio S, Cherniavsky A, Sueta CA, Roy A, Piña IL, Wurm R, Drazner MH, Andersson B, Batlle C, Senni M, Chrzanowski L, Merkely B, Carson P, Desvigne-Nickens PM, Lee KL, Velazquez EJ, Al-Khalidi HR, STICH Trial Investigators, Howlett, J, Stebbins, A, Petrie, M, Jhund, P, Castelvecchio, S, Cherniavsky, A, Sueta, C, Roy, A, Piña, I, Wurm, R, Drazner, M, Andersson, B, Batlle, C, Senni, M, Chrzanowski, L, Merkely, B, Carson, P, Desvigne-Nickens, P, Lee, K, Velazquez, E, Al-Khalidi, H, STICH Trial, I, Howlett JG, Stebbins A, Petrie MC, Jhund PS, Castelvecchio S, Cherniavsky A, Sueta CA, Roy A, Piña IL, Wurm R, Drazner MH, Andersson B, Batlle C, Senni M, Chrzanowski L, Merkely B, Carson P, Desvigne-Nickens PM, Lee KL, Velazquez EJ, Al-Khalidi HR, and STICH Trial Investigators
- Abstract
Objectives: The authors investigated the impact of coronary artery bypass grafting (CABG) on first and recurrent hospitalization in this population. Background: In the STICH (Surgical Treatment for Ischemic Heart Failure) trial, CABG reduced all-cause death and hospitalization in patients with and ischemic cardiomyopathy and left ventricular ejection fraction <35%. Methods: A total of 1,212 patients were randomized (610 to CABG + optimal medical therapy [CABG] and 602 to optimal medical therapy alone [MED] alone) and followed for a median of 9.8 years. All-cause and cause-specific hospitalizations were analyzed as time-to-first-event and as recurrent event analysis. Results: Of the 1,212 patients, 757 died (62.4%) and 732 (60.4%) were hospitalized at least once, for a total of 2,549 total all-cause hospitalizations. Most hospitalizations (66.2%) were for cardiovascular causes, of which approximately one-half (907 or 52.9%) were for heart failure. More than 70% of all hospitalizations (1,817 or 71.3%) were recurrent events. The CABG group experienced fewer all-cause hospitalizations in the time-to-first-event (349 CABG vs. 383 MED, adjusted hazard ratio [HR]: 0.85; 95% confidence interval [CI]: 0.74 to 0.98; p = 0.03) and in recurrent event analyses (1,199 CABG vs. 1,350 MED, HR: 0.78, 95% CI: 0.65 to 0.94; p < 0.001). This was driven by fewer total cardiovascular (CV) hospitalizations (744 vs. 968; p < 0.001, adjusted HR: 0.66, 95% CI: 0.55 to 0.81; p = 0.001), the majority of which were due to HF (395 vs. 512; p < 0.001, adjusted HR: 0.68, 95% CI: 0.52-0.89; p = 0.005). We did not observe a difference in non-CV events. Conclusions: CABG reduces all-cause, CV, and HF hospitalizations in time-to-first-event and recurrent event analyses. (Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease [STICH]; NCT00023595)
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- 2019
67. Diversity of Bradyrhizobium Strains Isolated from Endemic Woody Legumes of the Canary Islands by PCR-Restriction Fragment Length Polymorphism Analysis of 16S rDNA and Low-Molecular-Weight Rna Profiles
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Jarabo-Lorenzo, A., Velázquez, E., Pérez-Galdona, R., Vega-Hernández, M., Martínez-Molina, E., Mateos, P., Vinuesa, P., León-Barrios, M., Pedrosa, Fabio O., editor, Hungria, Mariangela, editor, Yates, Geoffrey, editor, and Newton, William E., editor
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- 2000
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68. Nature of the Beneficial Rhizobium leguminosarum Bv. Trifolii — Rice Association
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Yanni, Y. G., Rizk, R., Biswas, J., Ladha, J. K., Weinman, J., Rolfe, B., deBruijn, F., Ostrom, P., Vega-Hernandez, M., Marshall, E., Hollingsworth, S., Hollingsworth, R., Squartini, A., Martinez-Molina, E., Mateos, P., Velazquez, E., Dazzo, F., Pedrosa, Fabio O., editor, Hungria, Mariangela, editor, Yates, Geoffrey, editor, and Newton, William E., editor
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- 2000
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69. A Robust Approach to Control Blood Glucose Level: Diabetes Mellitus Type I
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Ruiz-Velázquez, E., Campos-Delgado, D.U., and Femat, R.
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- 2003
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70. Design of Reduced-Order Controllers via H∞ and Parametric Optimisation: Comparison for an Active Suspension System
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Campos-Delgado, D.U., Femat, R., and Ruiz-Velázquez, E.
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- 2003
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71. 4331Safety and efficacy of sacubitril/valsartan by dose level in patients hospitalized with acute heart failure: Observations from PIONEER-HF
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Morrow, D A, primary, Velazquez, E J, additional, Devore, A D, additional, Duffy, C I, additional, Gurmu, Y, additional, McCague, K, additional, Rocha, R, additional, and Braunwald, E, additional
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- 2019
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72. 1135Angiotensin receptor-neprilysin inhibition in patients with de novo acute decompensated heart failure: a prespecified subgroup analysis of the PIONEER-HF trial
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Ambrosy, A, primary, Braunwald, E, additional, Morrow, D, additional, Devore, A, additional, McCague, K, additional, Duffy, C, additional, Rocha, R, additional, and Velazquez, E, additional
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- 2019
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73. P1233Differential effects of five risk variants for atrial fibrillation at the 4q25 region on L-type calcium current and transient inward currents in human atrial myocytes
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Tarifa, C, primary, Herraiz-Martinez, A, additional, Llach, A, additional, Jimenez-Sabado, V, additional, Colino, H, additional, Lozano-Velazquez, E, additional, Franco, D, additional, Rosello, E, additional, Rodriguez-Font, E, additional, Cinca, J, additional, and Hove-Madsen, L, additional
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- 2019
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74. Gold nanoparticles (AuNP) exert immunostimulatory and protective effects in shrimp (Litopenaeus vannamei) against Vibrio parahaemolyticus
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Tello-Olea, M., primary, Rosales-Mendoza, S., additional, Campa-Córdova, A.I., additional, Palestino, G., additional, Luna-González, A., additional, Reyes-Becerril, M., additional, Velazquez, E., additional, Hernandez-Adame, L., additional, and Angulo, C., additional
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- 2019
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75. Context-aware stress detection
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Janssens, Olivier, Smets, E, Schavione, G., Rios Velazquez, E., Ongenae, Femke, De Raedt, W, Van Hoof, C., and Van Hoecke, Sofie
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ispartof: BHI ispartof: IEEE Biomedical and Health Informatics (BHI'18) location:Las Vegas date:4 Mar - 7 Mar 2018 status: accepted
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- 2017
76. Cross reactivity between peach and some dry fruits
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Durán, S., Bartolomé, B., Gámez, R., Velazquez, E., Lopez Crespo, R., Delgado, J., Gonzalez Pol, J., and Conde, J.
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- 1998
77. Contact urticaria from sunflower seeds
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Duran, S., Delgado, J., Gamez, R., Velazquez, E., Gonzalez-Pol, J., Serrano, P., Lopez-Crespo, R., Guardia, P., and Condé, J.
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- 1997
78. PINE PINASTER: A NEW ETHIOLOGICAL AGENT OF OCCUPATIONAL DISEASE IN CARPENTERS : P 276
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Moreno, V., Hernandez, M., Sanchez, M. C., Velazquez, E., Escribano, M., Gonzalez, J., Guardia, P., de la Calle, A., and Conde, J.
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- 1996
79. CHERRY HYPERSENSITIVITY : P 249
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Escribano, M., Velazquez, E., Muñoz, F. J., Sánchez, M. C., de la Calle, A., Monteseirín, J., and Conde, J.
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- 1996
80. Review: Defect chemistry and electrical properties of sodium bismuth titanate perovskite
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Yang, F., Li, M., Li, L., Wu, P., Pradal-Velazquez, E., and Sinclair, D.
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The ferroelectric perovskite Na0.5Bi0.5TiO3, NBT, can exhibit three types of electrical behaviour, i.e. oxide-ion conduction (Type I), mixed ionic-electronic conduction (Type II) and insulating/dielectric (Type III) based on various defect mechanisms. Here we review how to tune the electrical properties of NBT via several mechanisms, including A-site Na or Bi non-stoichiometry, isovalent substitution, acceptor- and donor-doping. The diversity of electrical behaviour in the NBT lattice is attributed to the high level of oxide-ion conductivity originating from highly mobile oxygen ions which can be fine-tuned to optimise or suppress the ionic conduction. High oxide-ion conductivity can be obtained by manipulating the starting Na/Bi ≥ 1 and by acceptor-doping to make NBT a potential electrolyte material for intermediate temperature solid oxide fuel cells (IT-SOFCs). In contrast, the oxide-ion conduction can be partially or fully suppressed by having a starting (nominal) composition with Na/Bi < 1, donor-doping, or utilising the trapping between oxygen vacancies and some B-site acceptor dopants. This significantly reduces the dielectric loss and makes NBT-based materials excellent candidates as high-temperature dielectrics for capacitor applications.
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- 2017
81. Impact of Spontaneous Extracranial Bleeding Events on Health State Utility in Patients with Atrial Fibrillation: Results from the ENGAGE AF‐TIMI 48 Trial
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Senior, R., Paul, J., McKnight, T., Formoso, I., Saravia Toledo, S., Codutti, O., Sanjurjo, M., Bowen, L., Sanchez, A., Alvarez, M., Rodriguez, M., Navarrete, S., Ramos, H., Venturini, C., Prado, A., Fernandez, E., Pozzer, D., Casares, E., Povedano, G., Tommasi, A., Piskorz, D., Verdini, E., Nul, D., Gandur, H., Muntaner, J., Funes, I., Marino, J., Calderon, M., Manuale, O., Carne, M., Mackinnon, I., Raimondi, G., Lotti, J., Shatsky, K., Rodkey, K., Lorente, C., Vignau, S., Llanos, J., Nigro, A., Litvak, B., Iglesias, M., Liniado, G., Belcuore, M., Lanternier, G., Monaco, F., Kevorkian, R., Jure, D., Jure, H., Bianchini, M., Avery, D., Hominal, M., von Wulffen, M., McKenzie, M., Miranda, J., Wright, L., Pye, M., Flint, L., Newby, D., Andrews, A., Goicoechea, R., Huerta, M., Giannaula, R., Eden, M., Giacomi, G., Ceirano, C., Garrido, M., Perlo, D., Garcia Duran, R., Meiller, F., Gant Lopez, J., Zanotti, A., Fuselli, J., Arrieta, M., Femenia, F., Falu, E., Facello, M., Facello, A., Murdoch, D., Helliwell, L., More, R., Isted, C., Maxwell, T., Jones, D., Marazzi, P., McGhee, C., MacLeod, M., Ebano, P., MacCallum, P., Davolos, M., Estol, C., Moreno, V., Dran, R., Cendali, G., D'Amico, A., Bocanera, M., Cuneo, C., Rosell, M., Cuello, J., Morandini, M., Colombo, H., Brown, R., Saa Zarandon, R., Caruso, O., Novas, V., Cartasegna, L., Fracaro, V., Caccavo, A., Saravia, M., Bustamante Labarta, G., Valle, M., Budassi, N., Lip, G., Finlayson, M., Linker, N., McGuire, K., Atkinson, C., Lindsay, S., Ramasamy, V., Lie, F., Dickinson, D., Douglas, H., D'Costa, D., Wilmott, R., Cohen, A., Duff, J., Choy, A., Davies, D., Chapman, O., Dougal, K., Camm, J., Price, R., Blagden, M., Schwarz, L., McGarvey, J., Stubbs, L., McCartney, M., Hicks, T., Massin, E., Bedenko, E., Marenberg, M., Rabadi-Marar, D., Dunn, S., Beeton, I., Smith, S., Aggarwal, R., Marar, I., Hernandez, S., Berli, M., Petrucci, J., Beloscar, J., Caceres, M., Amuchastegui, M., Ameriso, P., Ameriso, S., Garcia, M., Alvarez, C., Reguero, M., Allall, O., Rosales, E., Albisu, J., Ahuad Guerrero, R., Gonzalez, C., Vogelmann, O., Magnuson, Elizabeth A., Cohen, David J., Giugliano, Robert P., Mandviwala, M., Casas, R., Makam, S., Lisiecki, B., Mainigi, S., Doctor, A., Magee, A., Bush, D., Macomber, J., Edelstein, J., Lurie, M., Wright, H., Lui, H., Ault, S., Looby, R., Davids, M., Lone, B., Shah, D., Lomnitz, D., Wofford, E., Littlefield, R., Murphy, R., Ling, L., Miller, D., Lillestol, M., Bonds, C., Lewis, D., Hartley, L., Lesser, M., Smith, D., Lentz, M., Royse, H., Ledbetter, L., Faucett, S., Langevin, E., Simmons, T., Lang, J., Ferguson, D., Landau, C., Coyle, G. Stagi, Lambert, C., Jauregui, V., Laliotis, A., Marquez, D., Krichmar, P., Watts, S., Kozlowski, J., Sanchez, E., Kotha, P., Godfrey, C., Korpas, D., Averett, P., Kindman, L., Khan, G., Khan, M., Binns, M., Khan, B., DiCorcia, L., Kesselbrenner, M., Buhler, A., Kersh, R., Bartholomaus, D., Kerkering, M., Keller, J., Keller, R., Davis, C., Kastelic, R., Behm, K., Karunaratne, H., Ruggiero, M., Kapoor, A., Cook, S., Kaplan, K., Kostedt, G., Kandath, D., Dugal, J., Kai, W., Coombs, V., Kahn, B., Royes, A., Judson, P., Nichols, M., Jovin, I., Hughett, G., Jones, R., Phillips, T., Johnson, F., Andresen, T., Jardula, M., Butcher, S., Ison, R., Tambawala, M., Hussain, M., Garza, M., Hurst, P., Battistelli, E., Hunter, J., Truva, C., Huang, P., Craft, D., Howard, L., Hays, D., Howard, V., Adams, K., Houchin, V., Turner, N., Hotchkiss, D., Sloss, D., Horton, K., Homayouni, A., Homan, J., Young, C., Hoekstra, J., Dutter, S., Hippert, R., Vieira, P., Hinchman, D., Carey, G., Herson, S., Miranda, D., Herrod, J., Batchell, K., Hermany, P., Harkins, V., Henry, S., Millard, D., Henderson, D., Dandekar, U., Heiman, M., Krater, C., Hearne, S., Bobade, M., Harris, J., Cavanna, L., Han, M., Bentivenga, L., Hamroff, G., Morelli, L., Hack, T., McLean, R., Gvora, T., Felsman, D., Guthrie, R., Foster, B., Guerrero, Guerrero, Fisher, M., Guarnieri, T., Gabela, W., Guarino, J., Mabe, K., Grove, D., Davis, A., Grossman, C., Goodman, V., Griffin, J., Aull, L., Griffin, S., Bonora, M., Graham, S., Rafala, E., Gowda, S., Goldstein, M., Latteri, J., Goldscher, D., Ewing, B., Gogia, H., Keane-Richmond, P., Gillespie, E., Hinchion, N., Gerber, J., Valentine, H., George, F., Garb, J., Jones, J., Gaffney, M., Smith, K., Friedlander, I., Morales, C., French, W., Gentry, P., Franco, M., Thrope, C., Frais, M., Solis, A., Forman, S., Slayton, C., Flores, E., Donahue, S., Fishbein, G., Drew, B., Fischell, T., Lim, G., Finkelstein, S., Shriver, D., Finkel, M., Calvo, M., Fialkow, J., Prior, J., Felten, W., Tang, N., Feldman, J., Tameron, A., Feld, L., Watkins, D., Fahmy, R., DeSalle, D., Everhart, B., Shipp, A., Ettinger, N., O'Brien, J., Johnson, C., Erenrich, N., Cristaldi, J., Ellis, J., Quick, R., Eldadah, Z., Dunn, K., Eade, J., Cullen, T., D'Souza, A., Habibi, S., Drozdiak, R., Olson, A., Dotani, I., Rodriguez, L., Donovan, D., Tisdale, L., DiGiovanna, M., Ucik, S., Dhar, S., Briscoe, C., Devenport, S., Waters, L., Desire, A., Steward, A., Desai, A., Carey, J., DeGarmo, R., Warmack, D., Dean, J., Debes, C., De Lemos, J., Ebreo, N., Davuluri, A., Dave, B., Dave, K., Wulf, A., Datta, S., Leka, G., Daniels, S., Morgan, T., Dang, N., Sarpola, N., Curtis, B., Nelson, L., Cowan, L., Masson, E., Cottiero, R., Mullinax, K., Cossu, S., Svadbik, L., Corbett, B., Martinez, E., Concha, M., Cole, J., Salpas, S., Colan, D., Bossaers, J., Cohen, R., Dutka, C., McClelland, M., Clay, A., Clapp, T., Bagby, J., Ciaramita, J., Sawaya, K., Chaturvedi, S., Tamayo, M., Charlat, M., Hatfield, G., Chang, M., Phan, D., Carr, K., Jameson, L., Caplan, J., Hartranft, E., Canosa, R., Canaday, D., Morton, S., Cader, C., Al-Maliky, T., Bybee, K., Triano, A., Brown, H., Frey, W., Brilakis, E., Terry, P., Bradley, A., Ziegler, K., Bowden, W., Wade, W., Bouchard, A., Hickenbotham, D., Borsheim, M., Vernon, M., Blue, B., Bloomberg, K., Bloomberg, R., Ensminger, E., Blonder, R., Talbot-Lawson, C., Block, T., Antonino, M., Bingham, S., Langone, L., Bilazarian, S., Preston, S., Bilal, B., Eldred, R., Bernard, J., Ibarra, M., Berk, M., Garman, V., Bensimhon, D., Swaim, D., Beinart, S., Craig, M., Bedwell, N., Luis-Valdes, M., Bedoya, R., Hoffman, T., Beasley, R., Benton, J., Bartkowiak, A., Gordon, L., Barrington, P., Faircloth, C., Barker, T., Altonen, D., Barber, M., Campbell, G., Baman, R., Batista, M., Baine, S., Thompson, B., Ayesu, K., Baldwin, E., Awasty, V., Cobos, D., Aude, Y., Strickland, S., Attanti, S., Rasmussen, L., Arouni, A., Shoaf, R., Arnold, T., York, T., Anderson, J., Persechino, F., Amin, M., Khetarpal, S., Amin, K., Lane, B., Alsheikh, T., MacDonald, H., Almquist, A., Biscardi, R., Allison, J., Godsey, W., Aliyar, P., Genova-Peeva, E., Alexander, J., Brubaker, S., Akhter, F., Ahmadpour, H., Hussain, A., Ahmad, A., Beck, P., Reiling, S., Adler, P., Barash, B., Adler, J., Lohman, J., Panella, M., Abi-Mansour, P., Roberts, J., Mackin, A., Moriarty, A., Green, M., Shandra, T., Zhurba, S., Logvinov, Y., Zharinov, O., Mudruk, I., Yena, L., Nahrebetskyy, V., Yagensky, A., Serik, S., Volkov, V., Goncharov, O., Vizir, V., Sklyanna, O., Vatutin, M., Drapchak, I., Vakaliuk, I., Tykhonova, S., Kuznetsov, I., Tseluyko, V., Lyzohub, S., Sychov, O., Perebetiuk, L., Stanislavchuk, M., Sirenko, Y., Zamlynskyy, M., Shvetz, N., Goncharova, I., Shcherbak, V., Ishchuk, V., Shatilo, V., Rudyk, I., Chendey, T., Rishko, M., Gamachek, O., Rebrov, B., Leonidova, V., Prokhorov, O., Nekrasa, A., Potapenko, P., Dovgan, N., Parkhomenko, A., Ushakova-Sokolova, L., Ostrovska, 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H., Iriarte, M., Morissette, A., Wang, Kaijun, Li, Haiyan, and Yalcin, R.
- Subjects
Male ,medicine.medical_specialty ,Complications ,Time Factors ,Pyridines ,Health Status ,Embolism ,Hemorrhage ,Arrhythmias ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,Risk Factors ,Surveys and Questionnaires ,Internal medicine ,Atrial Fibrillation ,Humans ,Medicine ,In patient ,Prospective Studies ,030212 general & internal medicine ,anticoagulation ,Blood Coagulation ,Original Research ,Aged ,Aged, 80 and over ,Quality and Outcomes ,business.industry ,Anticoagulants ,Atrial fibrillation ,Middle Aged ,bleeding ,medicine.disease ,Stroke ,Thiazoles ,Treatment Outcome ,quality of life ,utility ,Physical therapy ,Cardiology ,Female ,Warfarin ,Gastrointestinal Hemorrhage ,Cardiology and Cardiovascular Medicine ,business ,TIMI ,Health Services and Outcomes Research ,Factor Xa Inhibitors - Abstract
Background The impact of different types of extracranial bleeding events on health‐related quality of life and health‐state utility among patients with atrial fibrillation is not well understood. Methods and Results The ENGAGE AF ‐ TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation–Thrombolysis in Myocardial Infarction 48) Trial compared edoxaban with warfarin with respect to the prevention of stroke or systemic embolism in atrial fibrillation. Data from the EuroQol‐5D ( EQ ‐5D‐3L) questionnaire, prospectively collected at 3‐month intervals for up to 48 months, were used to estimate the impact of different categories of bleeding events on health‐state utility over 12 months following the event. Longitudinal mixed‐effect models revealed that major gastrointestinal bleeds and major nongastrointestinal bleeds were associated with significant immediate decreases in utility scores (−0.029 [−0.044 to −0.014; P P =0.001], respectively). These effects decreased in magnitude over time, and were no longer significant for major nongastrointestinal bleeds at 9 months, but remained borderline significant for major gastrointestinal bleeds at 12 months. Clinically relevant nonmajor and minor bleeds were associated with smaller but measurable immediate impacts on utility (−0.010 [−0.016 to −0.005] and −0.016 [−0.024 to −0.008]; P Conclusions All categories of bleeding events were associated with negative impacts on health‐state utility in patients with atrial fibrillation. Major bleeds were associated with relatively large immediate decreases in utility scores that gradually diminished over 12 months; clinically relevant nonmajor and minor bleeds were associated with smaller immediate decreases in utility that persisted over 12 months. Clinical Trial Registration URL: https://www.clinicaltrials.gov/ . Unique identifier: NCT00781391.
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- 2017
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82. Rapid Prototyping of Neuro-Fuzzy Inverse Optimal Control as Applied to T1DM Patients
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Rios, Y. Yuliana, primary, Garcia-Rodriguez, J.A., additional, Sanchez, Edgar N., additional, Alanis, Alma Y., additional, and Ruiz-Velazquez, E., additional
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- 2018
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83. P803Validation of the universal definition of perioperative bleeding in adults cardiac surgery
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Gutierrez-Zarate, D, primary, Bucio-Reta, E R, additional, Barron-Magdaleno, C, additional, Aceves-Velazquez, E D, additional, Manzano-Lopez, U E, additional, Ayala-Leon, M, additional, and Baranda-Tovar, F M, additional
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- 2018
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84. P2735Relationship between renal perfusion pressure and diastolic perfusion pressure with the incidence of acute kidney injury in patients that underwent cardiac surgery
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Aceves Velazquez, E D, primary, Ayala-Leon, M, additional, Bucio-Reta, E R, additional, Barron-Magdaleno, C, additional, Gutierrez-Zarate, D, additional, Manzano-Lopez, U, additional, and Baranda-Tovar, F M, additional
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- 2018
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85. Inverse Optimal Control Using A Neural Multi-Step Predictor For T1DM Treatment
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Rios, Y. Yuliana, primary, Garcia-Rodriguez, J. A., additional, Sanchez, Oscar D., additional, Sanchez, Edgar N., additional, Alanis, Alma Y., additional, Ruiz-Velazquez, E., additional, and Arana-Daniel, Nancy, additional
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- 2018
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86. Multifactorial decision support systems in radiation oncology : clinical predictors and radiomics
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Rios Velazquez, E., Rios Velazquez, E., Rios Velazquez, E., and Rios Velazquez, E.
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- 2014
87. Developing consensus measures for global programs: Lessons from the Global Alliance for Chronic Diseases Hypertension research program.
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Li X., Oldenburg B., Riddell M., Srikanth V., Heritier S., Kalyanram K., Kartik K., Suresh O., Maulik P., Salam A., Sudhir T., Thankappan K., Thirunavukkarasu S., Varma R., Thomas N., Clifford G., Prabhakaran D., Thom S., Shivashankar R., Mohan S., Reddy K.S., Krishnan A., Faletoese S., Ieremia M., Ulberg C., Viali S., Pillay A., Sukhu A., Schultz J., Siitia J., Snowdon W., Antonio Bernabe-Ortiz, Cardenas M.K., Gilman R.H., Miranda J.J., Diez-Canseco F., Ponce-Lucero V., Sacksteder K., Gyamfi J., Ogedegbe O., Apusiga K., Cooper R., Ntim M., Plange-Rhule J., Rotich J., Binanay C., Finkelstein E., Bloomfield G., DeLong A., Hogan J., Inui T., Naanyu V., Fuster V., Horowitz C., Kimaiyo S., Kofler C., Menya D., Kamano J.H., Vedanthan R., Velazquez E., Were M., Dolan J., Irazola V., Krousel-Wood M., Augustovski F., Beratarrechea A., Chen J., He J., Mills K., Poggio R., Rubinstein A., Shi L., Webber L., Akinyemi R., Arulogun O., Hurst S., Waddy S., Warth S., Gebregziabher M., Uvere E., Riddell M.A., Edwards N., Thompson S.R., Bernabe-Ortiz A., Praveen D., Johnson C., Kengne A.P., Liu P., McCready T., Ng E., Nieuwlaat R., Ovbiagele B., Owolabi M., Peiris D., Thrift A.G., Tobe S., Yusoff K., de Villiers A., He F., MacGregor G., Jan S., Neal B., Chow C., Joshi R., MacMahon S., Patel A., Rodgers A., Webster R., Keat N.K., Attaran A., Mills E., Muldoon K., Yaya S., Featherstone A., Mukasa B., Forrest J., Kalyesubula R., Kamwesiga J., Lopez P.C., Tayari J.-C., Lopez P., Casas J.L., McKee M., Zainal A.O., Yusuf S., Campbell N., Kilonzo K., Marr M., Yeates K., Feng X., Yuan J., Lin C.-P., Yan L., Zhang J., Wu Y., Ma J., Wang H., Ma Y., Nowson C., Moodie M., Goudge J., Kabudula C., Limbani F., Masilela N., Myakayaka N., Gomez-Olive F.X., Thorogood M., Arabshahi S., Evans R., Mahal A., Li X., Oldenburg B., Riddell M., Srikanth V., Heritier S., Kalyanram K., Kartik K., Suresh O., Maulik P., Salam A., Sudhir T., Thankappan K., Thirunavukkarasu S., Varma R., Thomas N., Clifford G., Prabhakaran D., Thom S., Shivashankar R., Mohan S., Reddy K.S., Krishnan A., Faletoese S., Ieremia M., Ulberg C., Viali S., Pillay A., Sukhu A., Schultz J., Siitia J., Snowdon W., Antonio Bernabe-Ortiz, Cardenas M.K., Gilman R.H., Miranda J.J., Diez-Canseco F., Ponce-Lucero V., Sacksteder K., Gyamfi J., Ogedegbe O., Apusiga K., Cooper R., Ntim M., Plange-Rhule J., Rotich J., Binanay C., Finkelstein E., Bloomfield G., DeLong A., Hogan J., Inui T., Naanyu V., Fuster V., Horowitz C., Kimaiyo S., Kofler C., Menya D., Kamano J.H., Vedanthan R., Velazquez E., Were M., Dolan J., Irazola V., Krousel-Wood M., Augustovski F., Beratarrechea A., Chen J., He J., Mills K., Poggio R., Rubinstein A., Shi L., Webber L., Akinyemi R., Arulogun O., Hurst S., Waddy S., Warth S., Gebregziabher M., Uvere E., Riddell M.A., Edwards N., Thompson S.R., Bernabe-Ortiz A., Praveen D., Johnson C., Kengne A.P., Liu P., McCready T., Ng E., Nieuwlaat R., Ovbiagele B., Owolabi M., Peiris D., Thrift A.G., Tobe S., Yusoff K., de Villiers A., He F., MacGregor G., Jan S., Neal B., Chow C., Joshi R., MacMahon S., Patel A., Rodgers A., Webster R., Keat N.K., Attaran A., Mills E., Muldoon K., Yaya S., Featherstone A., Mukasa B., Forrest J., Kalyesubula R., Kamwesiga J., Lopez P.C., Tayari J.-C., Lopez P., Casas J.L., McKee M., Zainal A.O., Yusuf S., Campbell N., Kilonzo K., Marr M., Yeates K., Feng X., Yuan J., Lin C.-P., Yan L., Zhang J., Wu Y., Ma J., Wang H., Ma Y., Nowson C., Moodie M., Goudge J., Kabudula C., Limbani F., Masilela N., Myakayaka N., Gomez-Olive F.X., Thorogood M., Arabshahi S., Evans R., and Mahal A.
- Abstract
Background: The imperative to improve global health has prompted transnational research partnerships to investigate common health issues on a larger scale. The Global Alliance for Chronic Diseases (GACD) is an alliance of national research funding agencies. To enhance research funded by GACD members, this study aimed to standardise data collection methods across the 15 GACD hypertension research teams and evaluate the uptake of these standardised measurements. Furthermore we describe concerns and difficulties associated with the data harmonisation process highlighted and debated during annual meetings of the GACD funded investigators. With these concerns and issues in mind, a working group comprising representatives from the 15 studies iteratively identified and proposed a set of common measures for inclusion in each of the teams' data collection plans. One year later all teams were asked which consensus measures had been implemented. Result(s): Important issues were identified during the data harmonisation process relating to data ownership, sharing methodologies and ethical concerns. Measures were assessed across eight domains; demographic; dietary; clinical and anthropometric; medical history; hypertension knowledge; physical activity; behavioural (smoking and alcohol); and biochemical domains. Identifying validated measures relevant across a variety of settings presented some difficulties. The resulting GACD hypertension data dictionary comprises 67 consensus measures. Of the 14 responding teams, only two teams were including more than 50 consensus variables, five teams were including between 25 and 50 consensus variables and four teams were including between 6 and 24 consensus variables, one team did not provide details of the variables collected and two teams did not include any of the consensus variables as the project had already commenced or the measures were not relevant to their study. Conclusion(s): Deriving consensus measures across diverse research pro
- Published
- 2017
88. Contributors
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Abuin, P., Aghajanzadeh, Omid, Alanis, Alma Y., Ali, Mumtaz, Bhalerao, Vibha, Blandeau, Mathias, Dansa, Manuchi, Di Giamberardino, Paolo, Diwekar, Urmila, Falsafi, Ali, Ferramosca, A., Garcia, Aldo Pardo, García-Rodríguez, J.A., Godoy, J.L., González, A.H., Guerra, Thierry-Marie, Haddad, Wassim M., Herrera, Jorge, Hosseinzadeh, Mehdi, Iacoviello, Daniela, Ibeas, Asier, Ishfaq, M., Manca, Davide, Márquez-Martín, Eduardo, Meskin, Nader, NasimUllah, Nisal, Apoorva, Oliveira, Tiago Roux, Ortega-Ruiz, Francisco, Padmanabhan, Regina, Pereira Rodrigues, Victor Hugo, Pudlo, Philippe, Rafiq, Muhammad Mohsin, Reina-Tosina, Javier, Rios, Y.Yuliana, Rivadeneira, Pablo S., Roa-Romero, Laura María, Ruiz-Velázquez, E., Sanchez, Edgar N., Savoca, Adriana, Sereno, J.E., Sharifi, Mojtaba, Talaminos-Barroso, Alejandro, Tehrani, Fleur T., and Yenkie, Kirti
- Published
- 2020
- Full Text
- View/download PDF
89. Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48)
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Pan, Y. F., Lim, G., Desire, A., Tseng, W. K., Rost, Natalia S., Grammer, M., Khetarpal, S., Waseem, M., Zellner, C., Roper, E., Amin, M., Harden, M., Sababathi, R., Valpas, S., Bourlios, P., Kawaguchi, A., Mavronasiou, E., Pandurangi, U., Shams, S., Dichristin, U., Purayil, M. Padinhare, Munemasa, M., Angel, J., Gurusamy, P., Berni, A., Platner, N., Zeltser, D., El Jarroudi, M., Kisos, D., Haruna, T., Bernhardt, P., Coisne, D., Nakahara, Y., Li, W. M., Karamitsos, C., Tziortziotis, A., Essop, M., Nunkoo, T., Gani, M., Wilson, L., Kelfkens, Y., Mitha, I., Taljaard, J., Naidoo, D., Duki, Y., Snyders, F., Munnik, M., Soma, P., Johnston, H., Patki, N., Jasani, B., Van Der Merwe, N., Goosen, Y., Van Zyl, L., Le Roux, M., Venter, T., Wessels, L., Bae, H. J., Han, M. G., Cha, J. K., Kim, D. H., Cho, B. R., Ryu, D. R., Choi, H. H., Hong, K. S., Chung, W. S., Oh, Y. S., Han, S. H., Lee, K. H., Hong, T. J., Lee, H. W., Hyon, M. S., Jung, J. W., Jeon, H. K., Lee, J. M., Kang, D. H., Choi, K. J., Kim, C. J., Jin, E. S., Kim, D. S., Seo, J. S., Kim, H. S., Cha, M. J., Kim, J. T., Park, M. S., Kim, J. H., Park, J. H., Kim, J. S., Parekh, P., Vicente, C., Simoes, M., Carraro, A., Sobral Filho, D., Lustosa, E., Boas, F. Villas, Almeida, M., Zimmermann, S., Zimmermann, E. Burger, Kunkelova, V., Berka, L., Brodova, P., Bar, M., Bergovec, M., Vrazic, H., Matsushita, C., Premchand, R., Boyer, M., Bakliza, Z., Sutalo, K., Kirner, D., Steiner, R., Cvitkusic Lukenda, K., Samardzic, P., Buksa, B., Kartsagkoulis, E., Kaplan, P., Sopher, M., Young, G., Senior, R., Roberts, J., Mackin, A., Moriarty, A., Olympios, C., Green, M., Shandra, T., Zhurba, S., Logvinov, Y., Zharinov, O., Mudruk, I., Yena, L., Nahrebetskyy, V., Kraiz, I., Chompalova, B., Parishev, G., Kharalkar, H., Knezevic, A., Denchev, S., Usan, N., Kraydashenko, O., Milcheva, N., Stets, R., Donova, T., Gergova, V., Georgiev, B., Kostova, E., Goudev, A., Jaksic Jurinjak, S., Kinova, E., Hergeldjieva, V., Yagensky, A., Kamenova, P., Manolova, A., Vasilev, I., Mihov, A., Miteva, B., Kupnovytska, I., Mincheva, V., Jelic, V., Stoyanovski, V., Makar Ausperger, K., Nikolov, F., Vasilev, D., Pencheva, G., Kostov, K., Petranov, S., Boriani, G., Milusheva, T., Popov, A., Staneva, A., Momchilova-Lozeva, D., Francetic, I., Todorov, G., Nyagina, M., Tumbev, H., Tumbeva, D., Tzekova, M., Kitova, M., Manoylov, E., Dicker, D., Giovannelli, F., Archibald, J., Antle, S., Bhargava, R., Stafford, C., Bose, S., Hundseth, M., Cha, J., Otis, J., Romic, I., Ferri Certic, J., Chehayeb, R., Lepage, C., Tusek, S., Ciglenecki, N., Jeric, M., Chilvers, M., Car, S., Carevic, V., Vansickle, L., Kyyak, Y., Serik, S., Cleveland, D., Valley, S., Constance, C., Gauthier, M., Lasri, E., Costi, P., Masson, C., Coutu, B., Denis, I., du Preez, M., Kubanska, A., Dufresne, M., Krider, J., Eikelboom, J., Zondag, M., Fortin, C., Viau, C., Houbraken, D., Hatheway, R., Mabee, J., Bagatin, J., Lizogub, V., Atar, S., Heath, J., Scott, L., Ho, K., Perdomo Mejia, I., Ho, V., Hoag, G., Standring, R., Huynh, T., Perkins, L., Kouz, S., Roy, M., Labonte, R., Fuki, Y., Dewar, C., Lainesse, A., St-Germain, L., Lam, S., Lam, H., Lichtenstein, T., Roberts, P., Luton, R., Douglas, S., Sanchez Vallejo, G., Ma, P., Seib, M., MacCallum, C., Matthews, J., Malette, P., Vaillancourt, T., Maranda, C., Studenikow, E., Mawji, A., Morely, A., Morrison, D., Roth, M., Mucha, M., Volkov, V., Goncharov, O., Vizir, V., Sklyanna, O., Vatutin, M., Drapchak, I., Vakaliuk, I., Dharmarao, A., Zanwar, I., Thakur, B., Vinod, M. Vijan, Kaur, A., Marciano, C., Varma, S., Tykhonova, S., Kuznetsov, I., Tseluyko, V., Najarali, A., Lamoureux, U., Nicholson, R., O'Hara, G., Banville, P., O'Mahony, W., Bolton, R., Parkash, R., Carroll, L., Pesant, Y., Sardin, V., Polasek, P., Turri, L., Qureshi, A., Nethercott, C., Ricci, J., Gonzales, C., Gorna, O., Bozek, B., Rupka, D., Malynovsky, Y., Quintero, A., Belhassane, A., Fonseca, J., Orozco Linares, L., Marchand, C., Shu, D., Silverio, G., St-Hilaire, R., Fedotov, S., Morissette, A., Sussman, J., Ostrovska, L., Kailey, P., Syan, G., Lopez Giraldo, D., Moncada Corredor, M., Bobbie, C., Rivera Rodriguez, E., Talajic, M., David, D., Manzur, F., Talbot, P., Tremblay, M., Teitelbaum, I., Teitelbaum, J., Velthuysen, G., Giesbrecht, L., Wahby, R., Morley, A., Wharton, S., Caterini, T., Builes, A., Dimitra, K., Ajioka, M., Woodford, T., Balboa, W., Ushakova-Sokolova, L., Parkhomenko, A., Dovgan, N., Potapenko, P., Nekrasa, A., Prokhorov, O., Leonidova, V., Rebrov, B., Gamachek, O., Jaramillo Munoz, C., Daskalaki, A., Thankaraj, L., Moschos, N., Delgado, P., Hernandez, H., Aldana Diaz, I., Fernandez Ruiz, R., Arroyave, C., Delgado Restrepo, J., Leon Pineda, L., Srinivas, A., Cano, N., Accini, M., Accini, J., Zhang, Y. L., Zhou, S. X., Li, B. G., Zheng, Z. Q., Wang, J. Q., Zhao, X. L., Rishko, M., Chendey, T., Han, R. J., Zhao, R. P., Retamal Matus, L., Bugueno, C., Mondaca Mondaca, P., Cobos, J., Obreque, C., Corbalan, R., Parada, A., Kang, H., Gupta, R., Singh, G., Lyzohub, S., Florenzano, F., Arratia Diaz, P., Lopetegui, M., Rebolledo, C., Manriquez, L., Manriquez Silva, L., Martinez, D., Romero Llamas, R., Opazo, M., Carmona Perez, M., Pincetti, C., Torres Carrasco, G., Zhang, Z., Lin, Y. N., Rudyk, I., Zhang, H. Q., Qiang, H., Yuan, Z. Y., Li, L. L., Yu, B., Potthoff, S., Zapata Staub, J., Rodriguez, M., Campisto, Y., Xu, Y. P., Stockins, B., Lara Lara, C., Yovaniniz, P., Grandon Azua, M., Bai, F., Xu, G. L., Chen, J. Z., Xie, X. D., Chen, X. P., Zhang, X., Yin, Y. H., Gao, M., Dong, Y. G., Feng, C., Fu, G. S., Zhang, P., Miyauchi, Y., Hong, K., You, Z. G., Shatilo, V., Ishchuk, V., Zheng, Y., Hong, L., Zheng, X., Qiu, Y., Yang, Y. J., Shcherbak, V., Sudheer, R., Shetty, G., Li, A. Y., Goncharova, I., Yang, K., Liang, Y. Z., Xu, Y. M., Gu, J. Y., Xu, J. H., Li, Y. E., Wu, S. L., Huang, D., Wei, M., Shvetz, N., Shi, X. J., Wang, G. P., Qi, S. Y., Wang, D. M., Yang, Z. Y., Ma, S. M., Lu, Z. H., Liu, L., Gu, X. J., Sychov, O., Liao, D. N., Liu, Y., Zamlynskyy, M., Sirenko, Y., Stanislavchuk, M., Sethia, S., Sethia, A., Jiang, X. J., Li, Z. Q., Qu, Z., Li, L., Perebetiuk, L., Liu, H., Kandekar, B., Li, T. F., Liu, B., Raut, N., Kong, Y. Q., Hashimoto, Y., Jakala, P., Shimazu, Y., Hiasa, Y., Berger, N., Kale, V., Alexopoulos, D., Wurow, A., Filardi, P. Perrone, Al-Zoebi, A., Hoffmann, S., Viitaniemi, J., Dias, P., Oomaan, A., Murata, J., Natarajan, S., Narendra, J., Shelke, S., Duprat, C., Winter, K., Roudaut, R., Wolde, C., Buelow-Johansen, B., Oga, Y., Namjoshi, D., Lee, M. H., Leparree, S., Poulard, J., Nagai, Y., Sakata, Y., Naito, S., Oyama, H., Nishi, Y., Nagase, T., Ochiai, J., Junko, H., Ogawa, T., Sugeno, M., Oguro, H., Tanabe, M., Okada, K., Corbut, S., Moriyama, Y., Okajima, K., Nakashima, M., Okazaki, O., Wada, H., Kacet, S., Okishige, K., Kitani, S., Okumura, K., Deruche, E., Hermida, J., Dorn, S., Tsalihin, D., Hoffmann, U., Dieckheuer, U., Heuer, H., Winkelmann, B., Peitz, M., Hartmann, A., Otto, A., Grigat, C., Antman, Elliott M., Mercuri, Michele F., Ito, Y., Onishi, M., Iwade, K., SomaRaju, Bhupathi, Nicolau, Jose C., Singhal, Aneesh B., Silverman, Scott, Norden, Andrew D., Crompton, Andrea E., Murphy, Sabina A., Ruff, Christian T., Giugliano, Robert P., Narita, Y., Onaka, H., Moriyama, H., Ozaki, Y., Tanikawa, I., Sakagami, S., Nakano, A., Sakuragi, S., Hayashi, N., Sakurai, S., Ooki, H., Sasaki, T., Braunwald, Eugene, Oosawa, N., Satoh, A., Fujimoto, E., Seino, Y., Narumi, M., Shirai, T., Shigenari, M., Shoji, Y., Ueda, J., Manuela, W., Fuchs, R., Schneider, K., Sakuma, Y., Forck-Boedeker, K., Arfaoui, M., Dinanian, S., Joshi, H., Faghih, M., Weyland, K., Park, S. J., Kim, S. H., Buchholz, M., Seo, J. B., Kim, Y. J., Aggarwal, R., Smith, S., Beeton, I., Dunn, S., Blagden, M., Ito, T., Vogelmann, O., Gonzalez, C., Ahuad Guerrero, R., Belatsky, V., Swissa, M., Aloni, I., Sugi, K., Miyazaki, E., Price, R., Sumii, K., Camm, J., Asakura, H., Dougal, K., Chapman, O., Davies, D., Choy, A., Duff, J., Cohen, A., Wilmott, R., D'Costa, D., Douglas, H., Dickinson, D., Lie, F., Ramasamy, V., Lindsay, S., Takagi, M., Mohri, S., Takahashi, W., Yoshida, K., Voehringer, Voehringer, Thomas, R., Herfurth, B., Ludwig, I., Drescher, T., Kranz, P., Degtyareva, E., Ayasse, D., Veltkamp, R., Agraou, B., Zarpentin, C., Taggeselle, J., Stoehring, R., Shochat, M., Sterlin, J., Iwasaki, T., Schiff, E., Takahashi, A., Albisu, J., Rosales, E., Atkinson, C., Allall, O., Kishi, N., Linker, N., Finlayson, M., Bonin, K., Lip, G., Spitzer, S., Masaki, W., Akihisa, U., Hirahara, T., Furiozzi, F., Zaca, V., Takahashi, T., Sakurai, Y., Baylacher, M., Reguero, M., Sohn, H., Takeda, K., Gold, G., Yahata, A., Takenaka, T., Yamagishi, K., El Jarroudi, F., Sethi, K., Seibert, H., Takeuchi, S., Gagliano, M., Toschi, V., Breschi, M., Severi, S., Hussi, E., Watanabe, E., Cannoni, S., Rasura, M., Singh, R., Brown, R., Sawhney, J., Arora, T., Iesaka, Y., Higashikata, T., Miyamoto, C., Nagatome, H., Iijima, T., Higuchi, K., Kaarleenkaski, S., Ino, H., Hellmers, J., Noguchi, H., Schreckenberg, A., Schmidt, M., Schmidt, A., Schiewe, C., Dreykluft, K., Daut, W., Kakinoki, S., Finsterbusch, T., Adachi, C., Schenkenberger, I., Frommhold, R., Lioy, E., Penco, M., Schellong, S., Inomata, T., Nakamura, K., Kamakura, S., Granzow, K., Nakahara, F., Kamijo, M., Iida, S., Tanaka, K., Raisaro, A., Uchida, M., Tanouchi, J., Kamiyama, K., Nishiya, Y., Tsuboi, H., Tsuboi, N., Fujii, R., Terakura, K., Kato, K., Ishida, A., Kazatani, Y., Uematsu, M., Yasumoto, S., Ueyama, Y., MacCallum, P., Usuda, K., Sakai, Y., Yagi, M., Sato, A., Yagi, H., Kuroda, T., Yamabe, H., Ichikawa, Y., Sakamoto, Y., Yamada, T., Yamano, R., Kitazawa, H., Alvarez, C., Yamagishi, T., Sasaki, S., Yamamoto, Y., Yamashina, A., Chun, M. Y., Joung, B. Y., Igarashi, C., Ebano, P., Takiguchi, M., Yamashita, T., Matsuda, K., Yonehara, T., Yoshino, H., Nomura, H., MacLeod, M., Yoshioka, K., Fujiwara, Y., Bayram Llamas, E., Hurtado, A., Calvo Vargas, C., Cedano Limon, M., Kobayashi, Y., Cardona Munoz, E., Hernandez, S., Carrillo, J., Szymanowski, N., Schaefer, A., Kuehlenborg, A., Rinke, A., Delgadillo, T., Casares Ramirez, M., Franco Valles, J., Pilipenko, H., Rack, K., Garcia, M., Ameriso, S., Ameriso, P., Garcia, N., Alcantara Colin, M., Garcia-Castillo, A., McGhee, C., Jaramillo, A., Leiva-Pons, J., de la Mora, S., Marazzi, P., Llamas Esperon, G., Grajales, A., Amuchastegui, M., Jones, D., Mendez-Machado, G., Avila, H., Nevarez Ruiz, L., Magallanes, G., Sanchez Diaz, C., Ortiz, A., Kuhlmann, M., Maxwell, T., Velasco Sanchez, R., Logvinenko, S., Moran Velazquez, E., Isted, C., Alhakim, M., More, R., Helliwell, L., van Welsen, I., Bruning, T., Caceres, M., Jones, A., Buiks, C., de Groot, J., Radder, I., de Vos, R., Beloscar, J., Hazeleger, R., Daniels, R., Kietselaer, B., Muijs, L., Mannaerts, H., Kooiman, E., Mevissen, H., van der Heijden, D., Hofmeyer, H., Anscombe, R., O'Meeghan, T., Kjentjes, M., Benatar, J., White, H., Borthwick, L., Doughty, R., Copley, M., Fisher, R., Monkley, R., Green, B., Scott, D., Hamer, A., Tomlinson, J., Hart, H., Turner, A., Cammell, R., Troughton, R., Skelton, L., Young, C., Kennett, K., Atar, D., Claussen, H., Hofsoy, K., Melbue, R., Sandvik, J., Thunhaug, H., Tveit, A., Enger, S., Bustamante, G., Tejada Guillen, M., Cabrera, J., Esteves Mendoza, R., Chavez, C., Luna, C., Lema, J., Rozenman, Y., Givoni, H., Carrion, A., Proskynitopoulos, N., Pohl, W., Llerena, N., Lewinsky, D., Araoz Bedregal, S., Medina Palomino, F., Rodriguez, J., Minchola, J., Bautista, C., Negron Miguel, S., Honores Armas, B., Rodriguez, A., Romero, N., Torres, P., Murdoch, D., Fernandez Rodriguez, K., Yanac Chavez, P., Horna, M., Delgado, S., Babilonia, N., Sambaz, C. 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Rostasne, Palinkas, A., Berk, M., Nagy, A., Garman, V., Bensimhon, D., Swaim, D., Beinart, S., Craig, M., Bedwell, N., Luis-Valdes, M., Bedoya, R., Hoffman, T., Beasley, R., Kolumban, E., Merkely, B., Kiss, K., Wulf, M., Takeda, M., Benton, J., Bartkowiak, A., Gordon, L., Erdogan, D., Barrington, P., Faircloth, C., Barker, T., Altonen, D., Barber, M., Campbell, G., Baman, R., Batista, M., Baine, S., Thompson, B., Ayesu, K., Ermis, C., Alvarez, M., Sanchez, A., Bowen, L., Sanjurjo, M., Codutti, O., Saravia Toledo, S., Formoso, I., Schmidberg, J., Baldwin, E., Awasty, V., Cobos, D., Aude, Y., Strickland, S., Medvegy, M., Kiss, T., Attanti, S., Matoltsy, A., Rasmussen, L., Arouni, A., Shoaf, R., Arnold, T., York, T., Kabul, K., Kanadasi, M., Goloboulicz, A., Anderson, J., Schygiel, P., Buzzetti, C., Severino, P., Morara, P., Sosa Liprandi, M., Teves, M., Vico, M., Oto, A., Turgut, O., Persechino, F., Morell, Y., Amin, K., Lane, B., Alsheikh, T., MacDonald, H., Almquist, A., Anderson, C., Paraskevaidis, T., Kolk, R., Tandogan, I., Stern, A., Yigit, F., Yigit, Z., Arstall, M., Hoffmann, B., Colquhoun, D., Price-Smith, S., Crimmins, D., Slattery, A., Karakai, H. Horvathne, Lupkovics, G., Di Lenarda, A., Kovacs, Z., Gadepalli, R., Mariani, M., Kumagai, S., Luttermann, M., Krishnan, H., Dart, A., Venneklaas, U., Kay, S., Lueders, S., De Servi, S., Grosse, B., Davis, S., Baranyai, M., Silver, G., Flecknoe-Brown, S., Gates, P., Kovacs, I., Salminen, O., Koczka, M., Jakal, A., Jones, S., Pirelli, S., Lohrbaecher-Kozak, I., Bauch, F., Koenig, H., Lehman, R., Kiss, R., Saha, D., Barai, A., Roy, D., Bekal, S., Feil, J. Felfoldine, Meusel, P., Morrison, H., Biscardi, R., Kis, E., Hirayama, A., Allison, J., Godsey, W., Aliyar, P., Genova-Peeva, E., Kosztyu, M., Kleinecke-Pohl, U., Alexander, J., Brubaker, S., Akhter, F., Schoen, B., Reddy, R., Shankar, A. Ravi, Jungmair, W., Schmid, S., Junggeburth, J., De Pace, D., Ahmadpour, H., De Caterina, R., Hussain, A., Kaik, J., Ahmad, A., Beck, P., Zoghi, M., Batushkin, V., Fink, P., Reiling, S., Miyamoto, N., Adler, P., McKeirnan, M., Li, J., Paul, V., Batta, C., Serup-Hansen, K., Vuriya, A., Horacek, T., Schuppe, M., Kanakaridisz, N., Varga, A., Kimizu, T., Purnell, P., Perrett, L., Kishore, R., Szto, G., O'Shea, V., Capiau, L., Banaeian, F., De Bleecker, J., de Koning, K., De Tollenaere, M., Kara, M., Fiok, J., Szatmari, J., De Bruyne, L., Edes, I., Tsukimine, A., Muskoczki, E., Wiggers, H., Jakobsen, U., Torp-Pedersen, C., Forgione, C., Harada, K., Dioszeghy, P., Almaraz, S. Padilla, Desfontaines, P., Tincani, G., Heidbuchel, H., Camas, L. Velasquez, Cuccia, C., Meeusen, K., Herzet, J., Malmendier, D., Guerra, L., Mairesse, G., Raepers, M., Parque, J., Clinckemaille, N., Scavee, C., Samayoa, C. Sanchez, Pozuelos, J. Mayen, Arakawa, S., Huyberechts, D., Stockman, D., Jacobs, C., Vandekerckhove, Y., Svenningsen, A., Sand, N., Azhdari, M., Derycker, K., Peruzzotti, L., Comi, G., Vanwelden, J., Mino, K., Cervi, E., Sanchez, M., Gilat, T., van Welden, J., Vervoort, G., Mestdagh, I., Vrolix, M., Bazylevych, A., Vlasyuk, Z., Raae, D., Raymond, I., Beerts, C., Wollaert, B., Denie, D., Vincenzo de Paola, A. Amato, Coutinho, E., Lotufo, P. Andrade, de Melo, R. Ferreira, Atie, J., Motta, C., Alves da Costa, F. Augusto, Lahav, M., Estrada, M. Rodas, Ferraz, R. Franchin, Precoma, D. Bertolim, Guevara, S., Contzen, C., Weihrauch, D., Sehnem, E., Botelho, R., Cunha, S., Brondani, R., Fleck, N., Buhr, M., Kandekar, S., Ladenburger, K., Lavagnino, A. Ovando, Braun, R., Ishimaru, S., Chaves Junior, H., Silva, J., Costantini, C., Barroso, D., Jimenez, T., De Patta, M., Pereira, V., Duda, N., Bereznyakov, I., Laimer, R., Tomita, H., Ishii, Y., Dutra, O., Morgado, S., Saporito, W. Faustino, Seroqui, M., Ferreira, L., Araujo, E., Finimundi, H., Daitz, C., Gagliardi, R., Pereira, G., Gomes, M., Gomes, A., Guimaraes, A., Lebedynskaya, M., Petrovic, V., Overgaard, K., Ninho, L., Olsen, R., Nielsen, H., Jaeger, C., Barash, B., Veng-Olsen, T., Dotsenko, S., Pereira, L., Iversen, H., Madsen, H., Kulynych, R., Dzyak, G., Vasilyeva, L., Faynyk, A., Sorokivskyy, M., Gavrysyuk, V., Schnelzer, P., Ibsen, H., Adler, J., Dzublik, Y., Horbach, L., Husyev, V., Bouzo, M., Babbar, A., Loof, A., Blanc, J., Godlevska, O., Melgar, I. Guzman, Marcoviciu, D., Ramirez, V. de Leon, Sehr, B., Beyer-Westendorf, J., Vierbeck, S., Decoulx, E., Samburg, Y., Jorge, J., Cury, C., Karpenko, O., Hassager, C., Milla, O. Ayau, Kaiser, S., Christensen, L., Christensen, H., Dodt, K., Zidkova, E., Samkova, D., Vodnansky, P., Almeida, A., Kalil, C., Radaelli, G., Sebba Barroso de Souza, W. Kunz, Morales, K., Labrova, R., Nevolina, I., Karpenko, Y., Leaes, P., Luiz, R. Osorio, Blihar, O., Kaydashev, I., Berbari, H., Spinar, J., Spacek, R., Almeida, J. Pimenta, Gozalo, A., Slaby, J., Reichert, P., Jirsova, E., Podrazil, P., Gerasimenko, N., Pisova, J., Exarchou, E., Havlova, I., Petrova, I., Kifnidis, K., Reis, G., Kolomyyits, S., Peterka, K., Olsr, J., Bansal, N., Nechanicky, R., Vasylets, V., Kopytsya, M., Melichar, M., Krocova, E., Machova, V., Ludka, O., Petyunina, O., Kotseruba, V., Berrouschot, J., Kvasnicka, J., Avellar, K., Kuchar, R., Kovar, P., Katz Weiand, L. Reis, Korantanis, K., Kosek, Z., Kostkova, G., Leipelt, J., Rocha, J., Ishibashi, Y., Lohman, J., Panella, M., Nozaki, T., Abi-Mansour, P., Dvoieglazova, M., Pyrgakis, V., Koval, V., Ohirko, O., Kochrt, M., Kobza, R., Koval', O., Jirmar, R., Sakamoto, S., Jerabek, O., Jelinek, Z., Jarkovsky, P., Jandik, J., Hubac, J., Honkova, M., Barros, R., Gregor, P., Rao, M., Jambula, H., Golan, L., Anzai, T., Rodrigues, L., Rocha, M. Rubia, Rodrigues, A., Rodrigues, D., dos Santos, F. Rossi, Pagnan, L. Goncalves, Sampaio, R., do Val, R., Saraiva, J., Francek, L., Florian, J., Ferkl, R., Elbl, L., Cermak, O., Burianova, H., Brtko, M., Pinto, B., and Yalcin, R.
- Subjects
Male ,medicine.medical_specialty ,Pyridines ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Brain Ischemia ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Double-Blind Method ,Recurrence ,Edoxaban ,Internal medicine ,Atrial Fibrillation ,parasitic diseases ,Secondary Prevention ,medicine ,Humans ,Myocardial infarction ,cardiovascular diseases ,Stroke ,Aged ,Advanced and Specialized Nursing ,business.industry ,Hazard ratio ,Warfarin ,Anticoagulants ,Atrial fibrillation ,Thrombolysis ,Middle Aged ,medicine.disease ,nervous system diseases ,Thiazoles ,Treatment Outcome ,chemistry ,Anesthesia ,Cardiology ,Female ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,business ,030217 neurology & neurosurgery ,TIMI ,medicine.drug - Abstract
Background and Purpose— Patients with atrial fibrillation and previous ischemic stroke (IS)/transient ischemic attack (TIA) are at high risk of recurrent cerebrovascular events despite anticoagulation. In this prespecified subgroup analysis, we compared warfarin with edoxaban in patients with versus without previous IS/TIA. Methods— ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48) was a double-blind trial of 21 105 patients with atrial fibrillation randomized to warfarin (international normalized ratio, 2.0–3.0; median time-in-therapeutic range, 68.4%) versus once-daily edoxaban (higher-dose edoxaban regimen [HDER], 60/30 mg; lower-dose edoxaban regimen, 30/15 mg) with 2.8-year median follow-up. Primary end points included all stroke/systemic embolic events (efficacy) and major bleeding (safety). Because only HDER is approved, we focused on the comparison of HDER versus warfarin. Results— Of 5973 (28.3%) patients with previous IS/TIA, 67% had CHADS 2 (congestive heart failure, hypertension, age, diabetes, prior stroke/transient ischemic attack) >3 and 36% were ≥75 years. Compared with 15 132 without previous IS/TIA, patients with previous IS/TIA were at higher risk of both thromboembolism and bleeding (stroke/systemic embolic events 2.83% versus 1.42% per year; P P P P =0.02). No treatment subgroup interactions were found for primary efficacy ( P =0.86) or for intracranial hemorrhage ( P =0.28). Conclusions— Patients with atrial fibrillation with previous IS/TIA are at high risk of recurrent thromboembolism and bleeding. HDER is at least as effective and is safer than warfarin, regardless of the presence or the absence of previous IS or TIA. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT00781391.
- Published
- 2016
90. Cardioversion of Atrial Fibrillation in ENGAGE AF-TIMI 48
- Author
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Rostasne, Palinkas, A., Nagy, A., Kolumban, E., Merkely, B., Kiss, K., Medvegy, M., Kiss, T., Matoltsy, A., Karakai, H. Horvathne, Lupkovics, G., Kovacs, Z., Baranyai, M., Kovacs, I., Koczka, M., Jakal, A., Kiss, R., Feil, J. Felfoldine, Kis, E., Kosztyu, M., Kanakaridisz, N., Varga, A., Fiok, J., Szatmari, J., Edes, I., Muskoczki, E., Dioszeghy, P., Almaraz, S. Padilla, Camas, L. Velasquez, Guerra, L., Samayoa, C. Sanchez, Pozuelos, J. Mayen, Sanchez, M., Estrada, M. Rodas, Guevara, S., Lavagnino, A. Ovando, Jimenez, T., Melgar, I. Guzman, Ramirez, V. de Leon, Milla, O. Ayau, Korantanis, K., Pyrgakis, V., Kartsagkoulis, E., Olympios, C., Dimitra, K., Moschos, N., Daskalaki, A., Kifnidis, K., Exarchou, E., Karamitsos, C., Tziortziotis, A., Bourlios, P., Mavronasiou, E., Alexopoulos, D., Winter, K., Wolde, C., Buelow-Johansen, B., Winkelmann, B., Weyland, K., Buchholz, M., Voehringer, Voehringer, Ludwig, I., Veltkamp, R., Zarpentin, C., Taggeselle, J., Stoehring, R., Bonin, K., Spitzer, S., Baylacher, M., Sohn, H., Gold, G., Hellmers, J., Schreckenberg, A., Schmidt, M., Schmidt, A., Schiewe, C., Dreykluft, K., Finsterbusch, T., Schenkenberger, I., Frommhold, R., Schellong, S., Szymanowski, N., Schaefer, A., Kuehlenborg, A., Rinke, A., Pilipenko, H., Rack, K., Kuhlmann, M., Proskynitopoulos, N., Pohl, W., Lewinsky, D., Piechatzek, R., Raddatz, K., Mueller-Glamann, M., Barbera, S., Muegge, A., Vogt, S., Mitrovic, V., Frahm, E., Meyer-Pannwitt, U., Braemer, U., Meissner, G., Hoefer, K., Maus, O., Wulf, M., Luttermann, M., Venneklaas, U., Lueders, S., Grosse, B., Lohrbaecher-Kozak, I., Bauch, F., Koenig, H., Meusel, P., Kleinecke-Pohl, U., Schoen, B., Jungmair, W., Schmid, S., Junggeburth, J., Fink, P., Horacek, T., Schuppe, M., Hoffmann, S., Dorn, S., Hoffmann, U., Bobbie, C., Dieckheuer, U., Heuer, H., Peitz, M., Hartmann, A., Otto, A., Grigat, C., Manuela, W., Fuchs, R., Schneider, K., Forck-Boedeker, K., Faghih, M., Herfurth, B., Drescher, T., Kranz, P., Degtyareva, E., Ayasse, D., Daut, W., Kara, M., Contzen, C., Weihrauch, D., Buhr, M., Ladenburger, K., Braun, R., Schnelzer, P., You, Z. 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- Published
- 2016
91. Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48)
- Author
-
Jones, D., Gu, X. J., Liu, L., Grammer, M., Waseem, M., Roper, E., Harden, M., Zellner, C., Mason, T., Zeig, S., Curtis, S., Zakhary, B., Yousuf, K., Wharton, S., VonGerichten, S., Willis, J., Dowling, C., Williams, R., Gibson, C., Williams, D., Truva, C., Westcott, J., St Laurent, B., Weiss, R., Sanchez, G., Waxman, F., Locklear, T., Ward, S., Renaud, K., Walsh, R., Kilcup, S., Vossler, M., Washam, M., Vijay, N., Warren, K., Vicari, R., Parsons, T., Verma, S., Cardoza, T., Vemireddy, D., Harrelson, K. 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F., Le Heuzey, J., Nappila, H., Virtanen, V., Salminen, O., Rasi, H., Sankari, T., Nyman, K., Viitaniemi, J., Maenpaa, A., Laheaar, M., Lucijanic, T., Lappalainen, T., Jakala, P., Valpas, S., Hussi, E., Kaarleenkaski, S., Huikuri, H., Ratnik, E., Vahula, V., Rajasalu, R., Rosenthal, A., Voitk, J., Paumets, M., Rivis, L., Laane, E., Kolk, R., Stern, A., Kaik, J., Serup-Hansen, K., Wiggers, H., Jakobsen, U., Torp-Pedersen, C., Giesbrecht, L., Bagatin, J., Svenningsen, A., Carevic, V., Jiang, X. J., Sand, N., Raae, D., Raymond, I., Petrovic, V., Overgaard, K., Olsen, R., Nielsen, H., Veng-Olsen, T., Talajic, M., Iversen, H., Madsen, H., Ibsen, H., Loof, A., Hassager, C., Christensen, L., Christensen, H., Dodt, K., Zidkova, E., Samkova, D., Vodnansky, P., Labrova, R., Spinar, J., Spacek, R., Slaby, J., Reichert, P., Jirsova, E., Podrazil, P., Pisova, J., Havlova, I., Petrova, I., Peterka, K., Olsr, J., Nechanicky, R., Melichar, M., Krocova, E., Machova, V., Ludka, O., Kvasnicka, J., Kuchar, R., Kovar, P., Kosek, Z., Kostkova, G., Kochrt, M., Kobza, R., Jirmar, R., Jerabek, O., Jelinek, Z., Jarkovsky, P., Jandik, J., Hubac, J., Honkova, M., Gregor, P., Campisto, Y., Morissette, A., Sussman, J., Gao, M., Frahm, E., Golan, L., Mitrovic, V., Zheng, Y., Zapata Staub, J., Zheng, X., Francek, L., Florian, J., Ferkl, R., Elbl, L., Cermak, O., Burianova, H., Brtko, M., Kailey, P., Retamal Matus, L., Fonseca, J., Han, R. J., Velthuysen, G., Bugueno, C., Orozco Linares, L., Bobbie, C., Heath, J., Lopez Giraldo, D., Raddatz, K., Zhao, X. L., Voehringer, Voehringer, Scott, L., Ho, K., Ho, V., Chen, X. P., Car, S., Hoag, G., Bolton, R., O'Mahony, W., Banville, P., O'Hara, G., Nicholson, R., Lamoureux, U., Kunkelova, V., Najarali, A., Mucha, M., Roth, M., Morrison, D., Morely, A., Mawji, A., Studenikow, E., Maranda, C., Vaillancourt, T., Zhang, X., Dong, Y. G., Standring, R., Feng, C., Fu, G. S., Wang, J. Q., Beeton, I., Dunn, S., Blagden, M., Price, R., Camm, J., Dougal, K., Mondaca Mondaca, P., Chapman, O., Davies, D., Choy, A., Duff, J., Zheng, Z. Q., Wilmott, R., D'Costa, D., Douglas, H., Lie, F., Ramasamy, V., Lindsay, S., Atkinson, C., Moncada Corredor, M., Linker, N., Finlayson, M., Lip, G., Brown, R., MacCallum, P., Ebano, P., MacLeod, M., McGhee, C., Marazzi, P., Maxwell, T., Isted, C., More, R., Helliwell, L., Murdoch, D., Andrews, A., Newby, D., Flint, L., Pye, M., Wright, L., Avery, D., Senior, R., Young, G., Sopher, M., Kennard, S., Storey, R., Zhang, P., Bridge, C., Hong, K., Turner, W., Walker, M., Venkataraman, A., Gilchrist, M., Watkin, R., Chung, A., Wright, A., Wright, J., Cobos, J., Mueller-Glamann, M., Yang, Y. J., Jeric, M., Li, A. Y., Yang, K., Liang, Y. Z., Xu, Y. M., Gu, J. Y., Berka, L., Xu, J. H., You, Z. G., Li, Y. E., Syan, G., Hoefer, K., Rivera Rodriguez, E., Brodova, P., Ludwig, I., Obreque, C., Manzur, F., Builes, A., Hoffmann, U., Jaramillo Munoz, C., Dorn, S., Veltkamp, R., Hoffmann, S., Li, B. G., Potthoff, S., Bar, M., Vogt, S., Delgado, P., Zhou, S. X., Schuppe, M., Bergovec, M., Muegge, A., Teitelbaum, J., Barbera, S., Horacek, T., Torres Carrasco, G., Vrazic, H., Zhang, Y. L., Ciglenecki, N., Liao, D. N., Pincetti, C., Fink, P., Teitelbaum, I., Carmona Perez, M., Junggeburth, J., Liu, Y., Schmid, S., Li, Z. Q., Jungmair, W., Spitzer, S., Opazo, M., Lu, Z. H., Tusek, S., Ferri Certic, J., Romic, I., Francetic, I., Makar Ausperger, K., Jelic, V., Jaksic Jurinjak, S., Knezevic, A., Lichtenstein, T., Lam, H., Bakliza, Z., Sutalo, K., Lam, S., Romero Llamas, R., Ma, S. M., Huynh, T., St-Germain, L., Luton, R., Accini, J., Lainesse, A., Perkins, L., Douglas, S., Dewar, C., Ma, P., Kouz, S., Kirner, D., Steiner, R., Matthews, J., MacCallum, C., Cvitkusic Lukenda, K., Schoen, B., Kleinecke-Pohl, U., Meusel, P., Koenig, H., Bauch, F., Lohrbaecher-Kozak, I., Grosse, B., Lueders, S., Venneklaas, U., Luttermann, M., Wulf, M., Maus, O., Seib, M., Malette, P., Roberts, P., Yang, Z. Y., Roy, M., Labonte, R., Kong, Y. Q., Samardzic, P., Qu, Z., Hong, L., Buksa, B., Qiu, Y., Tremblay, M., Talbot, P., Accini, M., Hernandez, H., Wang, D. M., Qi, S. Y., Corbalan, R., Wang, G. P., Cano, N., Aldana Diaz, I., Shi, X. J., Martinez, D., Wu, S. L., Fernandez Ruiz, R., Manriquez Silva, L., Manriquez, L., Rebolledo, C., Wei, M., Leon Pineda, L., Arroyave, C., Lopetegui, M., Arratia Diaz, P., Huang, D., Florenzano, F., Parada, A., Bonin, K., Delgado Restrepo, J., Stoehring, R., Taggeselle, J., Zarpentin, C., Huikuri, Heikke, Puripun, E., Yarows, S., Giugliano, Robert P., Scirica, Benjamin M., Wood, K., Sheehan, T., Yasin, M., Worley, S., Ruff, Christian T., Link, Mark S., Pointer, S., Capasso-Gulve, E., Yi, J., Dongas, B., and Yalcin, R.
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Male ,medicine.medical_specialty ,medicine.drug_mechanism_of_action ,Pyridines ,medicine.medical_treatment ,Factor Xa Inhibitor ,Hemorrhage ,030204 cardiovascular system & hematology ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Edoxaban ,Risk Factors ,Physiology (medical) ,Internal medicine ,Thromboembolism ,Atrial Fibrillation ,Medicine ,Humans ,atrial fibrillation ,cardiovascular diseases ,030212 general & internal medicine ,Myocardial infarction ,Stroke ,Aged ,business.industry ,Warfarin ,Anticoagulants ,Atrial fibrillation ,Thrombolysis ,thromboembolism ,bleeding ,medicine.disease ,mortality ,stroke ,Thiazoles ,Treatment Outcome ,chemistry ,Anesthesia ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business ,TIMI ,medicine.drug ,Factor Xa Inhibitors - Abstract
Background— Whether the pattern of atrial fibrillation (AF) modifies the risk/benefit of anticoagulation is controversial. In ENGAGE AF-TIMI 48 trial (Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation–Thrombolysis in Myocardial Infarction 48), the factor Xa inhibitor edoxaban was noninferior to warfarin in preventing stroke or systemic embolic events and significantly reduced bleeding and cardiovascular mortality. However, detailed analyses by AF pattern have not been reported. Methods and Results— The 21 105 patients were categorized as having paroxysmal (P -adj =0.015) and permanent AF (1.95%/year; P -adj =0.004). Overall, all-cause mortality also was lower with paroxysmal (3.0%/year) compared with persistent (4.4%/year; P -adj P -adj Conclusions— In ENGAGE AF-TIMI 48 trial, patients with paroxysmal AF suffered fewer thromboembolic events and deaths compared with those with persistent and permanent AF. The efficacy and safety profile of edoxaban as compared with warfarin was consistent across the 3 patterns of AF. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT00781391.
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- 2016
92. Truncus Arteriosus in a 43 year old Male: Case Report
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Ng’eno, TK, Koech, MM, Yanoh, R, Foster, M, Velazquez, E, and Bloomfield, GS
- Abstract
In truncus arteriosus, the embryologic truncus fails to properly divide in-utero resulting in the pulmonary, aortic and coronary arteries arising from a single ascending portion of this trunk. This condition is usually fatal within the first year of life without correction. Over the past two decades, there has been a dramatic expansion in access to diagnostic echo cardiography in Kenya and greater ability to diagnose congenital heart diseases. We present the case of a 43 year old male from western Kenya, newly diagnosed with heart failure due to truncus arteriosus. This case highlights the value of echo-cardiography in Kenya, and supports the need for surgical and interventional cardiac services to grow in tandem with these diagnostic capabilities.
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- 2016
93. Healthy Parks Healthy People as an Upstream Stress Reduction Strategy
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Yoshino, Aiko, Wilson, Jackson, Velazquez, Edgar J., and Johnson, Eric
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- 2022
94. Robust glucose control via μ-synthesis in type 1 diabetes mellitus
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Morales-Contreras, Jonatan, primary, Ruiz-Velazquez, E., additional, and Garcia-Rodriguez, J.A., additional
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- 2017
- Full Text
- View/download PDF
95. Robust blood glucose regulation for Type II Diabetes Mellitus patients
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Herrera, Karla G., primary, Ruiz-Velazquez, E., additional, and Garcia-Rodriguez, J., additional
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- 2017
- Full Text
- View/download PDF
96. Effect of conservation of fish in formalin and ethanol on length-weight relationships and condition factor in Tlaloc labialis (Günther, 1866)
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Anzueto-Calvo, M. J., primary, Velázquez-Velazquez, E., additional, Matamoros, W. A., additional, Cruz Maza, B. G. A., additional, and Nettel-Hernanz, A., additional
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- 2017
- Full Text
- View/download PDF
97. Biomass fuel smoke exposure was associated with adverse cardiac remodeling and left ventricular dysfunction in Peru
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Burroughs Peña, M. S., primary, Velazquez, E. J., additional, Rivera, J. D., additional, Alenezi, F., additional, Wong, C., additional, Grigsby, M., additional, Davila-Roman, V. G., additional, Gilman, R. H., additional, Miranda, J. J., additional, and Checkley, W., additional
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- 2017
- Full Text
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98. Study on the ITO/ZnO interface and its effect on CdS/CdTe solar cell performance
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Zapata-Torres, M., Fernández-Muñoz, J. L., Hernández-Rodríguez, E., R. Mis-Fernández, Rejon, V., Peña, J. L., Valaguez-Velazquez, E., and Márquez Herrera, A.
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solar cell ,Física, Astronomía y Matemáticas ,ZnO ,Interface ,ITO - Abstract
"ZnO thin films have been deposited on ITO coated glass substrates, using RF magnetron reactive sputtering from a Zn target. The ZnO films were annealed at 560 °C for 1 hour, in order to promote the diffusion of the ITO into ZnO. The properties of the samples were analyzed by X- ray diffraction (XRD), UV-Vis spectroscopy and X-ray photoelectron spectroscopy (XPS). The ITO/ZnO interface showed a diffusion of 50 nm approximately. In order to study the effect of ZnO thickness, in the performance of the CdS/CdTe solar cell, we used an AMPS-1D solar simulator; the results showed that reduction of the ZnO thickness had a weak influence in the efficiency of the solar cell."
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- 2015
99. Cerebrovascular events in 21 105 patients with atrial fibrillation randomized to edoxaban versus warfarin: Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48
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Dougal, K., Venkataraman, A., Murdoch, D., Blagden, M., Dunn, S., MacCallum, P., Young, G., Lip, G., Senior, R., Brown, R., Sopher, M., Ebano, P., Linker, N., Atkinson, C., Lindsay, S., MacLeod, M., More, R., Ramasamy, V., Chapman, O., Lie, F., Beeton, I., McGhee, C., Wilmott, R., Dickinson, D., Douglas, H., Davies, D., D'Costa, D., Finlayson, M., Wright, A., Avery, D., Wright, L., Pye, M., Marazzi, P., Flint, L., Newby, D., Kennard, S., Andrews, A., Storey, R., Helliwell, L., Bridge, C., Choy, A., Turner, W., Walker, M., Wright, J., Smith, S., Jones, D., Maxwell, T., Chung, A., Isted, C., Cohen, A., Camm, J., Price, R., Watkin, R., Gilchrist, M., Duff, J., Aggarwal, R., Eldred, R., Adler, P., Chehayeb, R., Vandekerckhove, Y., Gordon, L., Jones, S., Young, C., Coyle, G. Stagi, Ferguson, D., Lang, J., Simmons, T., Langevin, E., Faucett, S., Ledbetter, L., Royse, H., Lentz, M., Smith, D., Lesser, M., Hartley, L., Lewis, D., Bonds, C., Lillestol, M., Miller, D., Ling, L., Murphy, R., Littlefield, R., Wofford, E., Lomnitz, D., Shah, D., Lone, B., Davids, M., Looby, R., Ault, S., Lui, H., Wright, H., Lurie, M., Edelstein, J., Macomber, J., Bush, D., Magee, A., Doctor, A., Mainigi, S., Lisiecki, B., Makam, S., Casas, R., Mandviwala, M., Hernandez, S., Marar, I., Rabadi-Marar, D., Marenberg, M., Bedenko, E., Massin, E., Hicks, T., McCartney, M., Stubbs, L., McGarvey, J., Schwarz, L., McGuire, K., Miranda, J., McKenzie, M., Rodkey, K., McKnight, T., Paul, J., McLaurin, B., Lack, A., Mega, J., Marti, J., Meholick, A., Skinner, J., Mehrle, A., Wall, J., Mendelson, R., Cervellione, K., Mercado, A., Cajulis, C., Michlin, B., Romero-Colon, J., Milas, J., Sanders, D., Miller, R., Sanchez, S., Miller, S., Gryczan, J., Mody, F., Strugatsky, S., Moran, J., Garner, S., Morledge, J., Bowman, B., Mouhaffel, A., Parrott, N., Mounsey, P., Schuler, C., Mowdy, M., Todd, S., Mullen, P., Raziano, S., Murphy, A., Oehmann, V., Nadar, V., Parker, A., Naidu, J., West, M., Nallasivan, M., Goza, J., Nguyen, T., Nomanee, S., Nielsen, R., Wilmot, M., Oberoi, M., Thakkar, N., Oppenheimer, K., McCormick, J., Orchard, R., Garcia, L., Osborne, J., Gonzalez, M., Oza, S., Joseph, L., Patnam, S., Dennison, K., Pavon, H., Gorry, N., Pearlstein, R., Montayne, S., Pentz, W., Duncan, D., Peters, P., Chacon, L., Petruzziello, F., Morlando, F., Pettis, K., Brown, F., Pezzella, S., Kirk, D., Poulathas, A., Cush, S., Pratt, R., Neeper, L., Pribble, A., Lowe, K., Pudi, K., Sham, L., Pugeda, J., Ebert, J., Quadrel, M., Rafla, E., Quinlan, E., Reed, C., Quinn, J., Hemmen, C., Rama, P., Domingo, D., Redondo, V., Wroblewski, J., Renzi, M., Stanley, E., Richwine, R., Pazier, P., Roberts, J., Riofrio, K., Braun, D., Robinson, J., Cherrico, M., Roehll, W., Hollihan, P., Rosado, J., Barnhorst, M., Rosen, R., Martin, C., Ross, S., Freeman, R., Ruoff, G., Nelson, T., Sacco, J., Ball, E., Samal, A., Schomburg, J., Sandberg, J., Lafave, J., Savin, V., Clifton, R., Schaefer, S., Fekete, A., Schneider, R., Schneider, W., Schulman, D., Mercer, S., Seals, A., Ullig, T., Holt, A., Seide, H., Mather, N., Shah, G., Witt, P., Shalaby, A., Seese, M., Shanes, J., Fleets, J., Shaoulian, E., Hren, A., Sheikh, K., Hengerer, T., Shih, H., Browning, J., Shoukfeh, M., Stephenson, L., Siler, T., Champagne, M., Simpson, P., Meyer, R., Singh, N., Turner, K., Singh, V., Nelson, M., Skierka, R., Hughes, B., Keene, R., Smith, R., Hodnett, P., Spangenthal, S., Thomason, L., Sperling, M., Vasquez, E., Spivack, E., McCartney, P., Staniloae, C., Liu, M., Steljes, A., Cox, C., Struble, R., Vittitow, T., Suresh, D., Frost, J., Swerchowsky, V., Freemyer, D., Szulawski, I., Herwehe, S., Tahirkheli, N., Springer, K., Takata, T., Bruton, T., Talano, J., Leo, L., Tami, L., Corchado, D., Tatarko, M., Swauger, M., Tawney, K., Dastoli, K., Teague, S., Young, K., Tee, H., Mitchell, T., Teixeira, J., Southam, D., Torres, M., Romero, N., Tucker, P., Salas, L., Updegrove, J., Hanna, K., Val-Mejias, J., Harrelson, K. Gonzalez, Vemireddy, D., Cardoza, T., Verma, S., Parsons, T., Vicari, R., Warren, K., Vijay, N., Washam, M., Vossler, M., Kilcup, S., Walsh, R., Renaud, K., Ward, S., Locklear, T., Waxman, F., Sanchez, G., Weiss, R., St Laurent, B., Westcott, J., Truva, C., Williams, D., Gibson, C., Williams, R., Dowling, C., Willis, J., VonGerichten, S., Wood, K., Capasso-Gulve, E., Worley, S., Pointer, S., Yarows, S., Sheehan, T., Yasin, M., Preston, S., Yi, J., Dongas, B., Yousuf, K., Fisher, M., Zakhary, B., Curtis, S., Zeig, S., Mason, T., Zellner, C., Harden, M., Roper, E., Waseem, M., Grammer, M., Ruff, Christian T., Giugliano, Robert P., Beerts, C., Vrolix, M., Mestdagh, I., Vervoort, G., van Welden, J., Vanwelden, J., Derycker, K., Jacobs, C., Stockman, D., Huyberechts, D., Scavee, C., Clinckemaille, N., Parque, J., Raepers, M., Mairesse, G., Malmendier, D., Herzet, J., Meeusen, K., Heidbuchel, H., Tincani, G., Desfontaines, P., De Bruyne, L., De Tollenaere, M., de Koning, K., De Bleecker, J., Banaeian, F., Capiau, L., O'Shea, V., Szto, G., Perrett, L., Purnell, P., Batta, C., Paul, V., Li, J., McKeirnan, M., George, F., Valentine, H., Gerber, J., Hinchion, N., Morrison, H., Lehman, R., Gates, P., Flecknoe-Brown, S., Silver, G., Davis, S., Kay, S., Dart, A., Slattery, A., Crimmins, D., Price-Smith, S., Colquhoun, D., Hoffmann, B., Arstall, M., Paraskevaidis, T., Anderson, C., Morell, Y., Vico, M., Teves, M., Sosa Liprandi, M., Morara, P., Severino, P., Buzzetti, C., Schygiel, P., Goloboulicz, A., Schmidberg, J., Formoso, I., Saravia Toledo, S., Codutti, O., Sanjurjo, M., Gillespie, E., Keane-Richmond, P., Gogia, H., Ewing, B., Goldscher, D., Latteri, J., Goldstein, M., Bowen, L., Sanchez, A., Alvarez, M., Rodriguez, M., Navarrete, S., Ramos, H., Venturini, C., Prado, A., Fernandez, E., Pozzer, D., Casares, E., Povedano, G., Tommasi, A., Piskorz, D., Verdini, E., Nul, D., Gandur, H., Muntaner, J., Funes, I., Marino, J., Calderon, M., Manuale, O., Carne, M., Mackinnon, I., Raimondi, G., Lotti, J., Shatsky, K., Lorente, C., Vignau, S., Llanos, J., Nigro, A., Litvak, B., Iglesias, M., Liniado, G., Belcuore, M., Lanternier, G., Monaco, F., Kevorkian, R., Jure, D., Jure, H., Bianchini, M., Hominal, M., von Wulffen, M., Goicoechea, R., Huerta, M., Giannaula, R., Eden, M., Giacomi, G., Ceirano, C., Garrido, M., Perlo, D., Garcia Duran, R., Meiller, F., Gant Lopez, J., Zanotti, A., Fuselli, J., Arrieta, M., Femenia, F., Iriarte, M., Falu, E., Facello, M., Facello, A., Davolos, M., Estol, C., Moreno, V., Dran, R., Cendali, G., D'Amico, A., Bocanera, M., Cuneo, C., Rosell, M., Cuello, J., Morandini, M., Colombo, H., Saa Zarandon, R., Caruso, O., Novas, V., Cartasegna, L., Fracaro, V., Caccavo, A., Saravia, M., Bustamante Labarta, G., Valle, M., Budassi, N., Berli, M., Petrucci, J., Beloscar, J., Caceres, M., Amuchastegui, M., Ameriso, P., Ameriso, S., Garcia, M., Alvarez, C., Reguero, M., Allall, O., Rosales, E., Albisu, J., Ahuad Guerrero, R., Gonzalez, C., Vogelmann, O., Braunwald, Eugene, Antman, Elliott M., Mercuri, Michele, Shi, Minggao, Dave, Jay, Duggal, Anil, Betcher, Joshua M., Grip, Laura T., Murphy, Sabina A., Deenadayalu, Naveen, Lowe, Cheryl, Wiviott, Stephen D., Silverman, Scott, Gowda, S., Rafala, E., Graham, S., Bonora, M., Griffin, S., Aull, L., Griffin, J., Goodman, V., Grossman, C., Davis, A., Grove, D., Mabe, K., Guarino, J., Gabela, W., Guarnieri, T., Guerrero, Guerrero, Foster, B., Guthrie, R., Felsman, D., Gvora, T., McLean, R., Rost, Natalia S., Hack, T., Morelli, L., Hamroff, G., Bentivenga, L., Han, M., Cavanna, L., Harris, J., Bobade, M., Hearne, S., Krater, C., Heiman, M., Dandekar, U., Henderson, D., Millard, D., Henry, S., Harkins, V., Hermany, P., Batchell, K., Herrod, J., Miranda, D., Herson, S., Carey, G., Hinchman, D., Vieira, P., Hippert, R., Dutter, S., Hoekstra, J., Homan, J., Homayouni, A., Horton, K., Sloss, D., Hotchkiss, D., Turner, N., Houchin, V., Adams, K., Howard, V., Hays, D., Howard, L., 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- Subjects
Male ,medicine.medical_specialty ,medicine.drug_mechanism_of_action ,medicine.drug_class ,Pyridines ,Factor Xa Inhibitor ,Infarction ,chemistry.chemical_compound ,Double-Blind Method ,Edoxaban ,Internal medicine ,Atrial Fibrillation ,medicine ,Humans ,Myocardial infarction ,cardiovascular diseases ,Stroke ,Aged ,Advanced and Specialized Nursing ,Dose-Response Relationship, Drug ,business.industry ,Anticoagulant ,Warfarin ,Anticoagulants ,Atrial fibrillation ,Middle Aged ,medicine.disease ,Thiazoles ,Treatment Outcome ,chemistry ,Anesthesia ,Cardiology ,Female ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,business ,medicine.drug - Abstract
Background and Purpose— The once-daily oral factor Xa inhibitor, edoxaban, is as effective as warfarin in preventing stroke and systemic embolism while decreasing bleeding in a phase III trial of patients with atrial fibrillation at moderate–high stroke risk. Limited data regarding cerebrovascular events with edoxaban were reported previously. Methods— We analyzed the subtypes of cerebrovascular events in 21 105 patients participating in Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48 (ENGAGE AF-TIMI 48) comparing outcomes among patients randomized to warfarin versus 2 edoxaban regimens (high dose, low dose). The primary end point for this prespecified analysis of cerebrovascular events was all stroke (ischemic plus hemorrhagic), defined as an abrupt onset of focal neurological deficit because of infarction or bleeding with symptoms lasting ≥24 hours or fatal in Results— Patients randomized to high-dose edoxaban had fewer strokes on-treatment (hazard ratio, 0.80; 95% confidence interval, 0.65–0.98) than warfarin (median time-in-therapeutic range, 68.4%); patients in the low-dose edoxaban group had similar rates (hazard ratio, 1.10 versus warfarin; 95% confidence interval, 0.91–1.32). Rates of ischemic stroke or transient ischemic attack were similar with high-dose edoxaban (1.76% per year) and warfarin (1.73% per year; P =0.81), but more frequent with low-dose edoxaban (2.48% per year; P Conclusions— In patients with atrial fibrillation, once-daily edoxaban was as effective as warfarin in preventing all strokes, with significant reductions in various subtypes of intracranial bleeding. Ischemic cerebrovascular event rates were similar with high-dose edoxaban and warfarin, whereas low-dose edoxaban was less effective than warfarin. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT00781391.
- Published
- 2014
100. Virulence factors enhance Citrobacter rodentium expansion through aerobic respiration
- Author
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Lopez, C. A., primary, Miller, B. M., additional, Rivera-Chavez, F., additional, Velazquez, E. M., additional, Byndloss, M. X., additional, Chavez-Arroyo, A., additional, Lokken, K. L., additional, Tsolis, R. M., additional, Winter, S. E., additional, and Baumler, A. J., additional
- Published
- 2016
- Full Text
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