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1,600 results on '"Tzankov, Alexandar"'

53. Phase 1/2a trial of intravenous BAL101553, a novel controller of the spindle assembly checkpoint, in advanced solid tumours

Author

Kristeleit, Rebecca, Evans, Jeffry, Molife, L. Rhoda, Tunariu, Nina, Shaw, Heather, Slater, Sarah, Haris, Noor R. Md, Brown, Nicholas F., Forster, Martin D., Diamantis, Nikolaos, Rulach, Robert, Greystoke, Alastair, Asghar, Uzma, Rata, Mihaela, Anderson, Stephanie, Bachmann, Felix, Hannah, Alison, Kaindl, Thomas, Lane, Heidi A., Larger, Patrice J., Schmitt-Hoffmann, Anne, Engelhardt, Marc, Tzankov, Alexandar, Plummer, Ruth, and Lopez, Juanita

Published
2020
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55. Molecular and functional profiling identifies therapeutically targetable vulnerabilities in plasmablastic lymphoma

Author

Frontzek, Fabian, Staiger, Annette M., Zapukhlyak, Myroslav, Xu, Wendan, Bonzheim, Irina, Borgmann, Vanessa, Sander, Philip, Baptista, Maria Joao, Heming, Jan-Niklas, Berning, Philipp, Wullenkord, Ramona, Erdmann, Tabea, Lutz, Mathias, Veratti, Pia, Ehrenfeld, Sophia, Wienand, Kirsty, Horn, Heike, Goodlad, John R., Wilson, Matthew R., Anagnostopoulos, Ioannis, Lamping, Mario, Gonzalez-Barca, Eva, Climent, Fina, Salar, Antonio, Castellvi, Josep, Abrisqueta, Pau, Menarguez, Javier, Aldamiz, Teresa, Richter, Julia, Klapper, Wolfram, Tzankov, Alexandar, Dirnhofer, Stefan, Rosenwald, Andreas, Mate, José Luis, Tapia, Gustavo, Lenz, Peter, Miething, Cornelius, Hartmann, Wolfgang, Chapuy, Björn, Fend, Falko, Ott, German, Navarro, José-Tomas, Grau, Michael, and Lenz, Georg

Published
2021
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57. Bone Marrow Infiltration of Angioimmunoblastic T-Cell Lymphoma: Identification and Prognostic Impact of Histologic Patterns and Diagnostic Application of Ancillary Phenotypic and Molecular Analyses

Author

Gerlach, Magdalena M., Juskevicius, Darius, Vela, Visar, Dirnhofer, Stefan, and Tzankov, Alexandar

Subjects
T cells, Non-Hodgkin's lymphomas, B cells, Ethylenediaminetetraacetic acid, Health
Abstract

* Context.--Angioimmunoblastic T-cell lymphomas originate from T follicular helper cells and express respective markers (BCL6, CD10, CXCL13, ICOS, and PD-1). Although commonly present, bone marrow involvement by angioimmunoblastic T-cell lymphoma can be diagnostically challenging. Additionally, only little is known about the distribution of T follicular helper cells in healthy and reactively changed bone marrows or in samples affected by other lymphomas. Objective.--To establish a diagnostic approach to reliably identify bone marrow infiltration of angioimmunoblastic T-cell lymphoma. Design.--We analyzed the morphologic infiltration pattern and the expression of T follicular helper-cell markers in 42 matched paired lymph node and bone marrow samples and applied comparative clonality testing. Furthermore, we studied the expression of BCL6 and PD-1 in a control cohort of healthy, reactively changed, and otherwise affected bone marrows. Results.--We identified 3 different bone marrow infiltration patterns correlating with overall survival (interstitial/micronodular infiltration with or without eosinophilia and diffuse infiltration with eosinophilia). The matched pairs showed a consistent (co)expression of PD-1 and BCL6 with a generally weaker expression in the bone marrow than in the lymph nodes. Comparative clonality testing was helpful in only a minority of cases. Infiltrates of the most important differential diagnoses contained either PD-1- or BCL6-positive tumor-infiltrating cells, but no coexpressing cells. Conclusions.--Bone marrow infiltration by angioimmunoblastic T-cell lymphoma displays 3 different patterns that correlate with prognosis. BCL6 and PD-1 can be reliably used to identify lymphoma infiltrates and to help rule out several differential diagnoses. Comparative clonality testing rarely provides additional value and cannot replace morphologic and phenotypic analyses. (Arch Pathol Lab Med. 2020;144:602-611; doi: 10.5858/arpa.2019-0007-OA), Angioimmunoblastic T-cell lymphoma (AITL) is the most common noncutaneous T-cell neoplasm in the Western world. (1) It is currently defined by the World Health Organization as a neoplasm of mature [...]

Published
2020
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58. Histologic features of hematopoietic stem cell transplant-associated thrombotic microangiopathy are best percepted in deep skin biopsies and renal biopsies, while showing a significant overlap with changes related to severe acute graft-versus-host disease in gastrointestinal biopsies

Author

Ehmann, Michelle Anna, Medinger, Michael, Bodenmann, Benjamin, Kraft, Sarah, Bollinger, Noémie, Heim, Dominik, Lengerke, Claudia, Tsakiris, Dimitrios A., Passweg, Jakob, Tzankov, Alexandar, and Menter, Thomas

Published
2020
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60. PD-1/PD-L1 expression and interaction by automated quantitative immunofluorescent analysis show adverse prognostic impact in patients with diffuse large B-cell lymphoma having T-cell infiltration: a study from the International DLBCL Consortium Program

Author

Li, Ling, Sun, Ruifang, Miao, Yi, Tran, Thai, Adams, Lisa, Roscoe, Nathan, Xu, Bing, Manyam, Ganiraju C., Tan, Xiaohong, Zhang, Hongwei, Xiao, Min, Tzankov, Alexandar, Visco, Carlo, Dybkaer, Karen, Bhagat, Govind, Tam, Wayne, Hsi, Eric D., van Krieken, J.Han, You, Hua, Huh, Jooryung, Ponzoni, Maurilio, Ferreri, Andrés J.M., Møller, Michael B., Piris, Miguel A., Zhang, Mingzhi, Winter, Jane N., Medeiros, L.Jeffrey, Rassidakis, George Z., Vaupel, Christine A., Li, Yong, Dakappagari, Naveen, Xu-Monette, Zijun Y., and Young, Ken H.

Published
2019
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63. Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment

Author

Araujo, Angela M., Abaurrea, Andrea, Azcoaga, Peio, Lopez-Velazco, Joanna I., Manzano, Sara, Rodriguez, Javier, Rezola, Ricardo, Egia-Mendikute, Leire, Valdes-Mora, Fatima, Flores, Juana M., Jenkins, Liam, Pulido, Laura, Osorio-Querejeta, Inaki, Fernandez-Nogueira, Patricia, Ferrari, Nicola, Viera, Cristina, Martin-Martin, Natalia, Tzankov, Alexandar, Eppenberger-Castori, Serenella, Alvarez-Lopez, Isabel, Urruticoechea, Ander, Bragado, Paloma, Coleman, Nicholas, Palazon, Asis, Carracedo, Arkaitz, Gallego-Ortega, David, Calvo, Fernando, Isacke, Clare M., Caffarel, Maria M., and Lawrie, Charles H.

Subjects
Cytokines -- Genetic aspects -- Health aspects, Oncology, Experimental, Cell differentiation -- Research, Connective tissue cells -- Genetic aspects -- Health aspects, Breast cancer -- Genetic aspects -- Development and progression, Cancer -- Research, Health care industry
Abstract

The tumor microenvironment (TME) is reprogrammed by cancer cells and participates in all stages of tumor progression. The contribution of stromal cells to the reprogramming of the TME is not well understood. Here, we provide evidence of the role of the cytokine oncostatin M (OSM) as central node for multicellular interactions between immune and nonimmune stromal cells and the epithelial cancer cell compartment. OSM receptor (OSMR) deletion in a multistage breast cancer model halted tumor progression. We ascribed causality to the stromal function of the OSM axis by demonstrating reduced tumor burden of syngeneic tumors implanted in mice lacking OSMR. Single-cell and bioinformatic analysis of murine and human breast tumors revealed that OSM expression was restricted to myeloid cells, whereas OSMR was detected predominantly in fibroblasts and, to a lower extent, cancer cells. Myeloid-derived OSM reprogrammed fibroblasts to a more contractile and tumorigenic phenotype and elicited the secretion of VEGF and proinflammatory chemokines CXCL1 and CXCL16, leading to increased myeloid cell recruitment. Collectively, our data support the notion that the stromal OSM/OSMR axis reprograms the immune and nonimmune microenvironment and plays a key role in breast cancer progression., Introduction The tumor microenvironment (TME), composed of different cell types (e.g., fibroblasts, adipocytes, endothelial and infiltrating immune cells), harbors complex cell interactions that are often manipulated and hijacked by tumor [...]

Published
2022
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65. Primary bone diffuse large B‐cell lymphoma (PB‐DLBCL): a distinct extranodal lymphoma of germinal centre origin, with a common EZB‐like mutational profile and good prognosis.

Author

Ivanova, Vanesa‐Sindi, Davies, John, Menter, Thomas, Wild, Damian, Müller, Anne, Krasniqi, Fatime, Stenner, Frank, Papachristofilou, Alexandros, Dirnhofer, Stefan, and Tzankov, Alexandar

Subjects
DIFFUSE large B-cell lymphomas, FOLLICULAR lymphoma, FLUORESCENCE in situ hybridization, LYMPHOMAS, MOLECULAR genetics
Abstract

Aims: Primary bone diffuse large B‐cell lymphoma (PB‐DLBCL) is not recognized as a separate entity by the current classification systems. Here we define and highlight its distinctive clinical presentation, morphology, phenotype, gene expression profile (GEP), and molecular genetics. Methods: We collected 27 respective cases and investigated their phenotype, performed gDNA panel sequencing covering 172 genes, and carried out fluorescence in situ hybridization to evaluate MYC, BCL2, and BCL6 translocations. We attempted to genetically subclassify cases using the Two‐step classifier and performed GEP for cell‐of‐origin subtyping and in silico comparison to uncover up‐ and downregulated genes as opposed to other DLBCL. Results: Most cases (n = 22) were germinal centre B‐cell‐like (GCB) by immunohistochemistry and all by GEP. Additionally, PB‐DLBCL had a mutational profile similar to follicular lymphoma and nodal GCB‐DLBCL, with the exception of more frequent TP53 and B2M mutations. The GEP of PB‐DLBCL was unique, and the frequency of BCL2 rearrangements was lower compared to nodal GCB‐DLBCL. The Two‐step classifier categorized eight of the cases as EZB, three as ST2, and one as MCD. Conclusion: This study comprehensively characterizes PB‐DLBCL as a separate entity with distinct clinical and morpho‐molecular features. These insights may aid in developing tailored therapeutic strategies and shed light on its pathogenesis. [ABSTRACT FROM AUTHOR]

Published
2024
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66. The biophysical and compositional properties of human basement membranes.

Author

Schoenenberger, Monica S., Halfter, Willi, Ferrand, Alexia, Halfter, Kathrin, Tzankov, Alexandar, Scholl, Hendrik P. N., Henrich, Paul Bernhard, and Monnier, Christophe A.

Abstract

Basement membranes are among the most widespread, non‐cellular functional materials in metazoan organisms. Despite this ubiquity, the links between their compositional and biophysical properties are often difficult to establish due to their thin and delicate nature. In this article, we examine these features on a molecular level by combining results from proteomics, elastic, and nanomechanical analyses across a selection of human basement membranes. Comparing results between these different membranes connects certain compositional attributes to distinct nanomechanical signatures and further demonstrates to what extent water defines these properties. In all, these data underline BMs as stiff yet highly elastic connective tissue layers and highlight how the interplay between composition, mechanics and hydration yields such exceptionally adaptable materials. [ABSTRACT FROM AUTHOR]

Published
2024
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68. Tumor-infiltrating normal B cells revealed by immunoglobulin repertoire clonotype analysis are highly prognostic and crucial for antitumor immune responses in DLBCL

Author

Xu-Monette, Zijun Y., primary, Li, Yong, additional, Snyder, Thomas, additional, Yu, Tiantian, additional, Lu, Tingxun, additional, Tzankov, Alexandar, additional, Visco, Carlo, additional, Bhagat, Govind, additional, Qian, Wenbin, additional, Dybkaer, Karen, additional, Chiu, April, additional, Tam, Wayne, additional, Zu, Youli, additional, Hsi, Eric D., additional, Hagemeister, Fredrick B., additional, Wang, Yingjun, additional, Go, Heounjeong, additional, Ponzoni, Maurilio, additional, Ferreri, Andrés J.M., additional, Moller, Michael B., additional, Parsons, Benjamin M., additional, Fan, Xiangshan, additional, van Krieken, J.Han, additional, Piris, Miguel A., additional, Winter, Jane N., additional, Au, Qingyan, additional, Kirsch, Ilan, additional, Zhang, Mingzhi, additional, Shaughnessy, John, additional, Xu, Bing, additional, and Young, Ken H., additional

Published
2023
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69. ETS1 phosphorylation at threonine 38 is associated with the cell of origin of diffuse large B cell lymphoma and sustains the growth of tumour cells

Author

Chung, Elaine Y. L., primary, Sartori, Giulio, additional, Ponzoni, Maurilio, additional, Cascione, Luciano, additional, Priebe, Valdemar, additional, Xu‐Monette, Zijun Y., additional, Fang, Xiaosheng, additional, Zhang, Mingzhi, additional, Visco, Carlo, additional, Tzankov, Alexandar, additional, Rinaldi, Andrea, additional, Sgrignani, Jacopo, additional, Zucca, Emanuele, additional, Rossi, Davide, additional, Cavalli, Andrea, additional, Inghirami, Giorgio, additional, Scott, David W., additional, Young, Ken H., additional, and Bertoni, Francesco, additional

Published
2023
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72. ZEB1 shapes AML immunological niches suppressing CD8 T-cell activity while fostering Th17 cell expansion

Author

Bassani, Barbara, primary, Simonetti, Giorgia, additional, Cancila, Valeria, additional, Ciciarello, Marilena, additional, Piva, Annamaria, additional, Chiodoni, Claudia, additional, Lecis, Daniele, additional, Gulino, Alessandro, additional, Fonzi, Eugenio, additional, Botti, Laura, additional, Portararo, Paola, additional, Costanza, Massimo, additional, Schwaller, Juerg, additional, Tzankov, Alexandar, additional, Ponzoni, Maurilio, additional, Ciceri, Fabio, additional, Bolli, Niccolò, additional, Curti, Antonio, additional, Tripodo, Claudio, additional, Colombo, Mario P., additional, and Sangaletti, Sabina, additional

Published
2023
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77. First-in human, phase 1, dose-escalation pharmacokinetic and pharmacodynamic study of the oral dual PI3K and mTORC1/2 inhibitor PQR309 in patients with advanced solid tumors (SAKK 67/13)

Author

Wicki, Andreas, Brown, Nicholas, Xyrafas, Alexandros, Bize, Vincent, Hawle, Hanne, Berardi, Simona, Cmiljanović, Nataša, Cmiljanović, Vladimir, Stumm, Michael, Dimitrijević, Saša, Herrmann, Richard, Prêtre, Vincent, Ritschard, Reto, Tzankov, Alexandar, Hess, Viviane, Childs, Alexa, Hierro, Cinta, Rodon, Jordi, Hess, Dagmar, Joerger, Markus, von Moos, Roger, Sessa, Cristiana, and Kristeleit, Rebecca

Published
2018
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78. Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma

Author

Wang, Xiaoxiao, Cao, Xin, Sun, Ruifang, Tang, Charlene, Tzankov, Alexandar, Zhang, Jun, Manyam, Ganiraju C., Xiao, Min, Miao, Yi, Jabbar, Kausar, Tan, Xiaohong, Pang, Yuyang, Visco, Carlo, Xie, Yan, Dybkaer, Karen, Chiu, April, Orazi, Attilio, Zu, Youli, Bhagat, Govind, Richards, Kristy L., Hsi, Eric D., Choi, William W.L., van Krieken, J. Han, Huh, Jooryung, Ponzoni, Maurilio, Ferreri, Andrés J.M., Møller, Michael B., Parsons, Ben M., Winter, Jane N., Piris, Miguel A., Li, Shaoying, Miranda, Roberto N., Medeiros, L. Jeffrey, Li, Yong, Xu-Monette, Zijun Y., and Young, Ken H.

Published
2018
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85. XPO1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53

Author

Deng, Manman, Zhang, Mingzhi, Xu-Monette, Zijun Y., Pham, Lan V., Tzankov, Alexandar, Visco, Carlo, Fang, Xiaosheng, Bhagat, Govind, Zhu, Feng, Dybkaer, Karen, Chiu, April, Tam, Wayne, Zu, Youli, Hsi, Eric D., Choi, William W. L., Huh, Jooryung, Ponzoni, Maurilio, Ferreri, Andrés J. M., Møller, Michael B., Parsons, Benjamin M., van Krieken, J. Han, Piris, Miguel A., Winter, Jane N., Hagemeister, Fredrick, Alinari, Lapo, Li, Yong, Andreeff, Michael, Xu, Bing, and Young, Ken H.

Published
2020
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86. Two distinct immunopathological profiles in autopsy lungs of COVID-19

Author

Nienhold, Ronny, Ciani, Yari, Koelzer, Viktor H., Tzankov, Alexandar, Haslbauer, Jasmin D., Menter, Thomas, Schwab, Nathalie, Henkel, Maurice, Frank, Angela, Zsikla, Veronika, Willi, Niels, Kempf, Werner, Hoyler, Thomas, Barbareschi, Mattia, Moch, Holger, Tolnay, Markus, Cathomas, Gieri, Demichelis, Francesca, Junt, Tobias, and Mertz, Kirsten D.

Published
2020
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87. Primary Bone Diffuse Large B-cell Lymphoma (PB-DLBCL) – a distinct extranodal lymphoma of germinal center origin, with an EZB-like mutational profile and good prognosis

Author

Ivanova, Vanesa-Sindi, primary, Davies, John, additional, Menter, Thomas, additional, Wild, Damian, additional, Müller, Anne, additional, Krasniqi, Fatime, additional, Stenner, Frank, additional, Papachristofilou, Alexandros, additional, Dirnhofer, Stefan, additional, and Tzankov, Alexandar, additional

Published
2023
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88. Supplementary Tables from Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL

Author

Xu-Monette, Ziju Y., primary, Xiao, Min, primary, Au, Qingyan, primary, Padmanabhan, Raghav, primary, Xu, Bing, primary, Hoe, Nicholas, primary, Rodríguez-Perales, Sandra, primary, Torres-Ruiz, Raul, primary, Manyam, Ganiraju C., primary, Visco, Carlo, primary, Miao, Yi, primary, Tan, Xiaohong, primary, Zhang, Hongwei, primary, Tzankov, Alexandar, primary, Wang, Jing, primary, Dybkær, Karen, primary, Tam, Wayne, primary, You, Hua, primary, Bhagat, Govind, primary, Hsi, Eric D., primary, Ponzoni, Maurilio, primary, Ferreri, Andrés J.M., primary, Møller, Michael B., primary, Piris, Miguel A., primary, van Krieken, J. Han, primary, Winter, Jane N., primary, Westin, Jason R., primary, Pham, Lan V., primary, Medeiros, L. Jeffrey, primary, Rassidakis, George Z., primary, Li, Yong, primary, Freeman, Gordon J., primary, and Young, Ken H., primary

Published
2023
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89. Data from Aggressive B-cell Lymphoma with MYC/TP53 Dual Alterations Displays Distinct Clinicopathobiological Features and Response to Novel Targeted Agents

Author

Deng, Manman, primary, Xu-Monette, Zijun Y., primary, Pham, Lan V., primary, Wang, Xudong, primary, Tzankov, Alexandar, primary, Fang, Xiaosheng, primary, Zhu, Feng, primary, Visco, Carlo, primary, Bhagat, Govind, primary, Dybkaer, Karen, primary, Chiu, April, primary, Tam, Wayne, primary, Zu, Youli, primary, Hsi, Eric D., primary, You, Hua, primary, Huh, Jooryung, primary, Ponzoni, Maurilio, primary, Ferreri, Andrés J.M., primary, Møller, Michael B., primary, Parsons, Benjamin M., primary, Hagemeister, Fredrick, primary, van Krieken, J. Han, primary, Piris, Miguel A., primary, Winter, Jane N., primary, Li, Yong, primary, Xu, Bing, primary, Liu, Phillip, primary, and Young, Ken H., primary

Published
2023
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90. Data from Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL

Author

Xu-Monette, Ziju Y., primary, Xiao, Min, primary, Au, Qingyan, primary, Padmanabhan, Raghav, primary, Xu, Bing, primary, Hoe, Nicholas, primary, Rodríguez-Perales, Sandra, primary, Torres-Ruiz, Raul, primary, Manyam, Ganiraju C., primary, Visco, Carlo, primary, Miao, Yi, primary, Tan, Xiaohong, primary, Zhang, Hongwei, primary, Tzankov, Alexandar, primary, Wang, Jing, primary, Dybkær, Karen, primary, Tam, Wayne, primary, You, Hua, primary, Bhagat, Govind, primary, Hsi, Eric D., primary, Ponzoni, Maurilio, primary, Ferreri, Andrés J.M., primary, Møller, Michael B., primary, Piris, Miguel A., primary, van Krieken, J. Han, primary, Winter, Jane N., primary, Westin, Jason R., primary, Pham, Lan V., primary, Medeiros, L. Jeffrey, primary, Rassidakis, George Z., primary, Li, Yong, primary, Freeman, Gordon J., primary, and Young, Ken H., primary

Published
2023
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91. Supplementary Tables 1-5 and Supplementary Figures 1-8 from Aggressive B-cell Lymphoma with MYC/TP53 Dual Alterations Displays Distinct Clinicopathobiological Features and Response to Novel Targeted Agents

Author

Deng, Manman, primary, Xu-Monette, Zijun Y., primary, Pham, Lan V., primary, Wang, Xudong, primary, Tzankov, Alexandar, primary, Fang, Xiaosheng, primary, Zhu, Feng, primary, Visco, Carlo, primary, Bhagat, Govind, primary, Dybkaer, Karen, primary, Chiu, April, primary, Tam, Wayne, primary, Zu, Youli, primary, Hsi, Eric D., primary, You, Hua, primary, Huh, Jooryung, primary, Ponzoni, Maurilio, primary, Ferreri, Andrés J.M., primary, Møller, Michael B., primary, Parsons, Benjamin M., primary, Hagemeister, Fredrick, primary, van Krieken, J. Han, primary, Piris, Miguel A., primary, Winter, Jane N., primary, Li, Yong, primary, Xu, Bing, primary, Liu, Phillip, primary, and Young, Ken H., primary

Published
2023
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92. EBV-positive DLBCL frequently harbors somatic mutations associated with clonal hematopoiesis of indeterminate potential

Author

Li, Yong, primary, Xu-Monette, Zijun Y., additional, Abramson, Jeremy, additional, Sohani, Aliyah R., additional, Bhagat, Govind, additional, Tzankov, Alexandar, additional, Visco, Carlo, additional, Zhang, Shanxiang, additional, Dybkaer, Karen, additional, Pan, Zenggang, additional, Xu, Min, additional, Tam, Wayne, additional, Zu, Youli, additional, Hsi, Eric D., additional, Hagemeister, Fredrick B., additional, Go, Heounjeong, additional, van Krieken, J. Han, additional, Winter, Jane N., additional, Ponzoni, Maurilio, additional, Ferreri, Andrés J. M., additional, Møller, Michael B., additional, Piris, Miguel A., additional, Wang, Yingjun, additional, Zhang, Mingzhi, additional, and Young, Ken H., additional

Published
2023
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93. Supplementary Figures 1-3 from Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL

Author

Xu-Monette, Ziju Y., primary, Xiao, Min, primary, Au, Qingyan, primary, Padmanabhan, Raghav, primary, Xu, Bing, primary, Hoe, Nicholas, primary, Rodríguez-Perales, Sandra, primary, Torres-Ruiz, Raul, primary, Manyam, Ganiraju C., primary, Visco, Carlo, primary, Miao, Yi, primary, Tan, Xiaohong, primary, Zhang, Hongwei, primary, Tzankov, Alexandar, primary, Wang, Jing, primary, Dybkær, Karen, primary, Tam, Wayne, primary, You, Hua, primary, Bhagat, Govind, primary, Hsi, Eric D., primary, Ponzoni, Maurilio, primary, Ferreri, Andrés J.M., primary, Møller, Michael B., primary, Piris, Miguel A., primary, van Krieken, J. Han, primary, Winter, Jane N., primary, Westin, Jason R., primary, Pham, Lan V., primary, Medeiros, L. Jeffrey, primary, Rassidakis, George Z., primary, Li, Yong, primary, Freeman, Gordon J., primary, and Young, Ken H., primary

Published
2023
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95. B-cell receptor–driven MALT1 activity regulates MYC signaling in mantle cell lymphoma

Author

Dai, Beiying, Grau, Michael, Juilland, Mélanie, Klener, Pavel, Höring, Elisabeth, Molinsky, Jan, Schimmack, Gisela, Aukema, Sietse M., Hoster, Eva, Vogt, Niklas, Staiger, Annette M., Erdmann, Tabea, Xu, Wendan, Erdmann, Kristian, Dzyuba, Nicole, Madle, Hannelore, Berdel, Wolfgang E., Trneny, Marek, Dreyling, Martin, Jöhrens, Korinna, Lenz, Peter, Rosenwald, Andreas, Siebert, Reiner, Tzankov, Alexandar, Klapper, Wolfram, Anagnostopoulos, Ioannis, Krappmann, Daniel, Ott, German, Thome, Margot, and Lenz, Georg

Published
2017
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99. Immunoglobulin somatic hypermutation has clinical impact in DLBCL and potential implications for immune checkpoint blockade and neoantigen-based immunotherapies

Author

Xu-Monette, Zijun Y., Li, Jianyong, Xia, Yi, Crossley, Beryl, Bremel, Robert D., Miao, Yi, Xiao, Min, Snyder, Thomas, Manyam, Ganiraju C., Tan, Xiaohong, Zhang, Hongwei, Visco, Carlo, Tzankov, Alexandar, Dybkaer, Karen, Bhagat, Govind, Tam, Wayne, You, Hua, Hsi, Eric D., van Krieken, J. Han, Huh, Jooryung, Ponzoni, Maurilio, Ferreri, Andrés J. M., Møller, Michael B., Piris, Miguel A., Winter, Jane N., Medeiros, Jeffrey T., Xu, Bing, Li, Yong, Kirsch, Ilan, and Young, Ken H.

Published
2019
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