251 results on '"Tuokko H"'
Search Results
52. Cued recall and memory disorders in dementia.
- Author
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Tuokko, H. and Crockett, D.
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- 1989
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53. Immune responses to live attenuated and inactivated mumps virus vaccines in seronegative and seropositive young adult males.
- Author
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Ilonen, J., Salmi, A., Tuokko, H., Herva, E., and Penttinen, K.
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- 1984
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54. Prospective controlled survey of viral infections in children with acute lymphoblastic leukemia during chemotherapy.
- Author
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Möttönen, Merja, Uhari, Matti, Lanning, Marjatta, Tuokko, Hanna, Möttönen, M, Uhari, M, Lanning, M, and Tuokko, H
- Published
- 1995
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55. The Assessment of Everyday Functioning Using the Present Functioning Questionnaire and the Functional Rating Scale in Elderly Samples.
- Author
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Crockett, D., Tuokko, H., Koch, W., and Parks, R.
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- 1989
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56. Positron emission tomography in patients with clinically diagnosed Alzheimer's disease.
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McGeer, P. L., Kamo, H., Harrop, R., Li, D. K. B., Tuokko, H., McGeer, E. G., Adam, M. J., Ammann, W., Beattie, B. L., Calne, D. B., Martin, W. R. W., Pate, B. D., Rogers, J. G., Ruth, T. J., Sayre, C. I., and Stoessl, A. J.
- Published
- 1986
57. Severe Head Injury Hastens Age of Onset of Alzheimer's Disease
- Author
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Gedye, A., Beattie, B.L., Tuokko, H., Horton, A., and Korsarek, E.
- Abstract
Head trauma has been found with greater frequency in the histories of Alzheimer patients than age‐matched controls in some studies, but not in others. We hypothesized that events that accelerate neuron loss, such as significant head trauma, hasten the onset of symptoms of Alzheimer's disease in persons vulnerable to the disorder. Retrospective data on 148 probable Alzheimer patients and 33 demented controls were examined. Alzheimer patients with severe head injury before the age of 65 showed onset of symptoms at an earlier age than Alzheimer patients without head trauma.
- Published
- 1989
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58. Comparison of nonspecific reactivity in indirect and reverse immunoassays for measles and mumps immunoglobulin M antibodies
- Author
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Tuokko, H
- Abstract
Serum specimens collected from patients convalescing from acute measles or mumps infections, other viral infections, or rheumatoid arthritis and from blood donors were tested in indirect and reverse assays for measles and mumps immunoglobulin M (IgM) antibodies. All the samples from patients convalescing from acute mumps and measles infections gave positive IgM results in both tests. However, 6% of sera from patients recovering from other viral infections, 68.4% of sera from patients with rheumatoid arthritis, and 5.6% of sera from normal blood donors gave false-positive results by the indirect measles IgM enzyme immunoassay (EIA). By the indirect mumps IgM EIA, 9% of sera from other viral infections, 70.1% of sera from patients with rheumatoid arthritis, and 5.6% of sera from normal blood donors gave false-positive reactions. The reverse test system for measles IgM gave false-positive results in 1.5% of sera from the group with other viral infections, and the reverse mumps EIA gave false-positive results in 0.9% of the patients. Other sera groups did not react in either measles or mumps reverse IgM assays. The results indicated that although nonspecific reactions are frequent in indirect IgM tests for viral antibodies, such reactions are rarely encountered when reverse IgM EIA tests are employed.
- Published
- 1984
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59. Central cholinergic deficiency wais profiles in a nondemented aged sample.
- Author
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Tuokko, H. and Crockett, D.
- Published
- 1987
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60. Validation of cognitive functioning categories in the Canadian Community Health Survey--Healthy Aging
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Leanne Findlay, Bernier, J., Tuokko, H., Kirkland, S., and Gilmour, H.
61. Patterns and health effects of caring for people with dementia: The impact of changing cognitive and residential status
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Mcdowell, I., Hill, G., Lindsay, J., Kristjansson, B., Helliwell, B., Chappell, N., Tuokko, H., Beattie, B. L., Howard Feldman, Sadovnick, D., Gutman, G., Hogan, D. B., Bland, R., Mccracken, P., Newman, S., Dobbs, A., D Arcy, C., Manfreda, J., Montgomery, P., Strain, L., Østbye, T., Steenhuis, R., Hachinski, V., Chambers, L., Raina, P., Cohen, C., Colantonio, A., Marshall, V., Snow, G., Kozak, J., Gauthier, S., Wolfson, C., Bergman, H., Panisset, M., Ska, B., Kergoat, M. J., Joanette, Y., Hébert, R., Verreault, R., Durand, P., Morin, J., Morin, M., Bouchard, R., Gauvreau, D., Fortier, I., Balram, C., Rockwood, K., Graham, J., Fisk, J., Macknight, C., Nilsson, T., Pedlar, D., Buehler, S., and Kozma, A.
62. Familial Alzheimer's Disease
- Author
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Sadovnick, A.D., primary, Tuokko, H., additional, Horton, A., additional, Baird, P.A., additional, Beattie, B.L., additional, and Spiegel, Sanford M., additional
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- 1988
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63. The Relationship Between Performance on the Multi-Focus Assessment Scale and Functional Status
- Author
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Tuokko, H., primary, Crockett, D., additional, Holliday, S., additional, and Coval, M., additional
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- 1987
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64. Adaptation of the cells ofEscherichia coli to the presence of hydroxyurea increases the level of inorganic pyrophosphatase activity
- Author
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Heinonen, J., primary, Joronen, I., additional, and Tuokko, H., additional
- Published
- 1976
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65. Direct and indirect measurement of physical activity in older adults: a systematic review of the literature
- Author
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Kowalski Kristina, Rhodes Ryan, Naylor Patti-Jean, Tuokko Holly, and MacDonald Stuart
- Subjects
Older adults ,Physical activity assessment ,Direct measurement ,Indirect measurement ,Self-report ,Questionnaires ,Accelerometry ,Pedometery ,Heart rate monitoring ,Indirect calorimetry ,Doubly labeled water ,Nutritional diseases. Deficiency diseases ,RC620-627 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Due to physiological and cognitive changes that occur with aging, accurate physical activity (PA) measurement in older adults represents a unique challenge. The primary purpose of this study was to systematically review measures of PA and their use and appropriateness with older adults. A secondary aim was to determine the level of agreement between PA measures in older adults. Methods Literature was identified through electronic databases. Studies were eligible if they examined the correlation and/or agreement between at least 2 measures, either indirect and/or direct, of PA in older adults (> 65 years of age). Results Thirty-six studies met eligibility criteria. The indirect and direct measures of PA across the studies differed widely in their ability to address the key dimensions (i.e., frequency, intensity, time, type) of PA in older adults. The average correlation between indirect and direct measures was moderate (r=0.38). The correlation between indirect and other indirect measures (r=0.29) was weak, while correlations between direct measures with other direct measures were high (real world: r= 0.84; controlled settings: r=0.92). Agreement was strongest between direct PA measures with other direct measures in both real world and laboratory settings. While a clear trend regarding the agreement for mean differences between other PA measures (i.e., direct with indirect, indirect with indirect) did not emerge, there were only a limited number of studies that reported comparable units. Conclusions Despite the lack of a clear trend regarding the agreement between PA measures in older adults, the findings underscore the importance of valid, accurate and reliable measurement. To advance this field, researchers will need to approach the assessment of PA in older adults in a more standardized way (i.e., consistent reporting of results, consensus over cut-points and epoch lengths, using appropriate validation tools). Until then researchers should be cautious when choosing measures for PA that are appropriate for their research questions and when comparing PA levels across various studies.
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- 2012
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66. Comparison of nucleic acid hybridization with enzyme immunoassay and isolation for detection of Chlamydia trachomatis.
- Author
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Tuokko, H., Ruuska, P., and Hyypiä, T.
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- 1989
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67. Predicting caregiver burden and depression in Alzheimer's disease.
- Author
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Clyburn LD, Stones MJ, Hadjistavropoulos T, and Tuokko H
- Abstract
OBJECTIVES: The purpose of this study was to investigate the predictors of caregiver burden and depression, including objective stressors and mediation forces influencing caregiving outcomes. METHODS: This investigation is based on the 1994 Canadian Study of Health and Aging (CSHA) database. Participants were 613 individuals with dementia, living in either the community or an institution, and their informal caregivers. Participants for the CSHA were identified by screening a large random sample of elderly persons across Canada. Structural equation models representing four alternative pathways from caregiving stressors (e.g., functional limitations, disturbing behaviors, patient residence, assistance given to caregiver) to caregiver burden and depression were compared. RESULTS: The data provided the best fit to a model whereby the effects on the caregiver's well-being are mediated by appraisals of burden. A higher frequency of disturbing behavior, caring for a community-dwelling patient, and low informal support were related to higher burden, which in turn led to more depressive symptomatology. Caregivers of patients exhibiting more disturbing behaviors and functional limitations received less help from family and friends, whereas those whose care recipients resided in an institution received more informal support. DISCUSSION: Our findings add to the preexisting literature because we tested alternative models of caregiver burden using an unusually large sample size of participants and after overcoming methodological limitations of past research. Results highlight the importance of the effective management of disturbing behaviors, the provision of formal services for caregivers with highly impaired patients and no informal support, and the improvement of coping skills in burdened caregivers. [ABSTRACT FROM AUTHOR]
- Published
- 2000
68. The Relationship Between Age, Dementia, Parkinsonism and Cerebral Glucose Metabolism in Neurodegenerative Disorders.
- Author
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Peppard, Richard F., Bhatt, M., Martin, W. R.W., Carr, G., Schulzer, M., McGeer, P. L., Tuokko, H., and Calne, D. B.
- Published
- 1989
69. Cerebral Glucose Metabolism in Normal Aging.
- Author
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Stoessl, A. J., Tuokko, H., Martin, W. R.W., McGeer, P. L., Pate, B. D., and Calne, D. B.
- Published
- 1986
70. Prevalence and severity of cognitive impairment with and without dementia in an elderly population.
- Author
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Graham JE, Rockwood K, Beattie BL, Eastwood R, Gauthier S, Tuokko H, and McDowell I
- Published
- 1997
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71. Older Drivers Reduced Engagement in Distracting Behaviors Over a Six-Year Period: Findings From the Candrive Longitudinal Study.
- Author
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Bédard M, Maxwell H, Weaver B, Stinchcombe A, Gélinas I, Mazer B, Naglie G, Porter MM, Rapoport MJ, Tuokko H, Vrkljan B, and Marshall S
- Subjects
- Male, Humans, Female, Aged, Aged, 80 and over, Longitudinal Studies, Data Collection, Automobile Driving
- Abstract
Objectives: Baltes and Baltes' "selective optimization with compensation" model is pertinent to driving but evidence about the use of compensation using longitudinal designs is scarce. Therefore, we sought to determine if older drivers reduced their engagement in distracting behaviors while driving, over a 6-year period., Methods: We used data captured over several annual assessments from a cohort of 583 drivers aged 70 and older to determine if their engagement in 12 distracting behaviors (e.g., listening to the radio, talking with passengers) declined over time. We adjusted our multivariable model for several potential confounders of the association between our outcome variable and time., Results: Overall, and after adjustment for potential confounders, the participants reduced their engagement in distracting behaviors over the study period (odds ratio [OR] = 0.96, 95% confidence interval [CI] = 0.95-0.97). Baseline age was negatively associated with engagement in distracting behaviors (OR = 0.95, 95% CI = 0.94-0.96). Men engaged in more distracting behaviors than women (OR = 1.15, 95% CI = 1.03-1.27), as did participants living in the largest urban centers compared to participants living in the smallest areas (OR = 1.21, 95% CI = 1.04-1.41). The number of kilometers driven per year (for every 10,000 km) was positively associated with the proportion of distracting behaviors drivers engaged in (OR = 1.13, 95% CI = 1.08-1.19)., Discussion: Drivers in our cohort reduced their engagement in distracting behaviors over the study period. This suggests that older drivers adjust their driving over time, which aligns with age-related theories and models about compensation., (© The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2024
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72. Candrive-Development of a Risk Stratification Tool for Older Drivers.
- Author
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Marshall S, Bédard M, Vrkljan B, Tuokko H, Porter MM, Naglie G, Rapoport MJ, Mazer B, Gélinas I, Gagnon S, Charlton JL, Koppel S, MacLeay L, Myers A, Mallick R, Ramsay T, Stiell I, Wells G, and Man-Son-Hing M
- Subjects
- Humans, Male, Aged, Aged, 80 and over, Female, Accidents, Traffic prevention & control, Canada epidemiology, Physical Examination, Risk Assessment, Automobile Driving psychology
- Abstract
Background: Assessing an older adult's fitness-to-drive is an important part of clinical decision making. However, most existing risk prediction tools only have a dichotomous design, which does not account for subtle differences in risk status for patients with complex medical conditions or changes over time. Our objective was to develop an older driver risk stratification tool (RST) to screen for medical fitness-to-drive in older adults., Methods: Participants were active drivers aged 70 and older from 7 sites across 4 Canadian provinces. They underwent in-person assessments every 4 months with an annual comprehensive assessment. Participant vehicles were instrumented to provide vehicle and passive Global Positioning System (GPS) data. The primary outcome measure was police-reported, expert-validated, at-fault collision adjusted per annual kilometers driven. Predictor variables included physical, cognitive, and health assessment measures., Results: A total of 928 older drivers were recruited for this study beginning in 2009. The average age at enrollment was 76.2 (standard deviation [SD] = 4.8) with 62.1% male participants. The mean duration for participation was 4.9 (SD = 1.6) years. The derived Candrive RST included 4 predictors. Out of 4 483 person-years of driving, 74.8% fell within the lowest risk category. Only 2.9% of person-years were in the highest risk category where the relative risk for at-fault collisions was 5.26 (95% confidence interval = 2.81-9.84) compared to the lowest risk group., Conclusions: For older drivers whose medical conditions create uncertainty regarding their fitness-to-drive, the Candrive RST may assist primary health care providers when initiating a conversation about driving and to guide further evaluation., (© The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America.)
- Published
- 2023
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73. Methodological considerations when establishing reliable and valid normative data: Canadian Longitudinal Study on Aging (CLSA) neuropsychological battery.
- Author
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O'Connell ME, Kadlec H, Griffith LE, Maimon G, Wolfson C, Taler V, Simard M, Tuokko H, Voll S, Kirkland S, and Raina P
- Subjects
- Humans, Longitudinal Studies, Neuropsychological Tests, Reproducibility of Results, Canada, Aging psychology
- Abstract
Objective: Creation of normative data with regression corrections for demographic covariates reduces risk of small cell sizes compared with traditional normative approaches. We explored whether methods of correcting for demographic covariates (e.g., full regression models versus hybrid models with stratification and regression) and choice of covariates (i.e., correcting for age with or without sex and/or education correction) impacted reliability and validity of normative data. Method: Measurement invariance for sex and education was explored in a brief telephone-administered cognitive battery from the Canadian Longitudinal Study on Aging (CLSA; after excluding persons with neurological conditions N = 12,350 responded in English and N = 1,760 in French). Results: Measurement invariance was supported in hybrid normative models where different age-based regression models were created for groups based on sex and education level. Measurement invariance was not supported in full regression models where age, sex, and education were simultaneous predictors. Evidence for reliability was demonstrated by precision defined as the 95% inter-percentile range of the 5
th percentile. Precision was higher for full regression models than for hybrid models but with negligible differences in precision for the larger English sample. Conclusions: We present normative data for a remotely administered brief neuropsychological battery that best mitigates measurement bias and are precise. In the smaller French speaking sample, only one model reduced measurement bias, but its estimates were less precise, underscoring the need for large sample sizes when creating normative data. The resulting normative data are appended in a syntax file.- Published
- 2022
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74. Perceived Community Age-friendliness is Associated With Quality of Life Among Older Adults.
- Author
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Mullen N, Stinchcombe A, Seguin C, Marshall S, Naglie G, Rapoport MJ, Tuokko H, and Bédard M
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- Aged, Humans, Self Report, Social Participation, Surveys and Questionnaires, Healthy Aging, Quality of Life
- Abstract
We examined the positive association between perceived community age-friendliness and self-reported quality of life for older adults. A total of 171 participants, aged 77-96 years, completed a mail-in questionnaire package that included measures of health (SF-36 Physical), social participation (Social Participation Scale), community age-friendliness (Age-Friendly Survey [AFS]), and quality of life (WHO Quality of Life). Hierarchical regression models including age, gender, driving status, finances, health, social participation, and AFS scores explained 8 to 21 per cent of the variance in quality of life scores. Community age-friendliness was a statistically significant variable in all models, accounting for three to six and a half per cent of additional variance in quality of life scores. Although the proportion of variance explained by age-friendliness was small, our findings suggest that it is worthwhile to further investigate whether focused, age-friendly policies, interventions, and communities could play a role towards successful and healthy aging.
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- 2022
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75. Psychotherapeutic Interventions for Dementia: a Systematic Review.
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Sukhawathanakul P, Crizzle A, Tuokko H, Naglie G, and Rapoport MJ
- Abstract
Background and Objectives: While a range of psychotherapeutic interventions is available to support individuals with dementia, comprehensive reviews of interventions are limited, particularly with regard to outcomes related to adjustment and acceptance. The current review assesses studies that evaluated the impact of various forms of psychotherapeutic interventions on acceptance and adjustment to changing life circumstances for older adults with cognitive impairment., Research Design and Methods: A systematic search of PubMed, PsycINFO, and CINAHL databases was conducted, restricted to articles published in English within the last 16 years (from 2003 to 2019). Twenty-four articles were identified that examined the effects of psychotherapeutic interventions on outcomes related to acceptance and adjustment which included internalizing symptoms, quality of life, self-esteem, and well-being. Fifteen studies examined interventions targeted towards individuals with cognitive impairment, while nine studies also targeted their caregivers., Results: Interventions that impacted outcomes related to acceptance and adjustment (e.g., adaptation, depressive symptoms, helplessness, self-esteem, and quality of life) varied in their theoretical approach, which incorporated elements of cognitive behavioural therapy (CBT), problem-solving therapy, psychotherapy, reminiscence therapy, interpersonal therapy, mindfulness-based therapy, and meaning-based, compassion-focused therapy. Among all interventions, reductions in depression were the most commonly reported treatment outcome particularly among interventions that incorporated problem-focused and meaning-based therapies. Mixed findings were reported with regard to outcomes related to helplessness, quality of life, self-esteem, and life satisfaction indices for individuals with cognitive impairment., Discussion and Implications: There is some support for the effectiveness of psychotherapeutic interventions on improving acceptance and adjustment in older adults with cognitive impairment, particularly with regard to reducing depressive symptoms., Competing Interests: CONFLICT OF INTEREST DISCLOSURES The authors declare that no conflicts of interest exist., (© 2021 Author(s). Published by the Canadian Geriatrics Society.)
- Published
- 2021
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76. Speeding and Speed Modification of Older Drivers: Does Vehicle Type Make a Difference?
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Cull AW, Porter MM, Nakagawa S, Smith GA, Rapoport MJ, Marshall SC, Bédard M, Tuokko H, Vrkljan B, Naglie G, Myers AM, and Mazer B
- Subjects
- Aged, Aged, 80 and over, Automobile Driving legislation & jurisprudence, Automobiles statistics & numerical data, Canada, Female, Humans, Longitudinal Studies, Male, Automobile Driving statistics & numerical data, Automobiles classification
- Abstract
The purpose of this study was to examine whether vehicle type based on size (car vs. other = truck/van/SUV) had an impact on the speeding, acceleration, and braking patterns of older male and female drivers (70 years and older) from a Canadian longitudinal study. The primary hypothesis was that older adults driving larger vehicles (e.g., trucks, SUVs, or vans) would be more likely to speed than those driving cars. Participants (n = 493) had a device installed in their vehicles that recorded their everyday driving. The findings suggest that the type of vehicle driven had little or no impact on per cent of time speeding or on the braking and accelerating patterns of older drivers. Given that the propensity for exceeding the speed limit was high among these older drivers, regardless of vehicle type, future research should examine what effect this behaviour has on older-driver road safety.
- Published
- 2020
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77. The Canadian longitudinal study on aging as a platform for exploring cognition in an aging population.
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Tuokko H, Griffith LE, Simard M, Taler V, O'Connell ME, Voll S, Kadlec H, Wolfson C, Kirkland S, and Raina P
- Subjects
- Aged, Aged, 80 and over, Canada, Female, Humans, Longitudinal Studies, Male, Middle Aged, Aging psychology, Cognition physiology
- Abstract
Objective: We present descriptive information on the cognitive measures used in the Canadian Longitudinal Study on Aging (CLSA) Comprehensive Cohort, relate this to information on these measures in the extant literature, and identify key considerations for their use in research and clinical practice. Method: The CLSA Comprehensive Cohort is composed of 30,097 participants aged 45-85 years at baseline who provided a broad range of sociodemographic, physical, social, and psychological health information via questionnaire and took part in detailed physical and cognitive assessments. Cognitive measures included: the Rey Auditory Verbal Learning Test - immediate and 5-min delayed recall, Animal Fluency, Mental Alternation Test (MAT), Controlled Oral Word Association Test (COWAT), Stroop Test - Victoria Version, Miami Prospective Memory Test (MPMT), and a Choice Reaction Time (CRT) task. Results: CLSA Comprehensive Cohort sample sizes were far larger than previous studies, and performances on the cognitive measures were similar to comparable groups. Within the CLSA Comprehensive Cohort, main effects of age were observed for all cognitive measures, and main effects of language were observed for all measures except the CRT. Interaction effects (language × age) were observed for the MAT, MPMT Event-based score, all time scores on the Stroop Test, and most COWAT scores. Main effects of education were observed for all measures except for the MPMT Time score in the French sample, and interaction effects (age × education) were observed for the RAVLT (immediate and delayed) for the English sample and the Stroop Dot time for the French sample. Conclusion: This examination of the cognitive measures used in the CLSA Comprehensive Cohort lends support to their use in large studies of health and aging. We propose further exploration of the cognitive measures within the CLSA to make this information relevant to and available for clinical practice.
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- 2020
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78. Corrigendum to: Cohort Profile: The Canadian Longitudinal Study on Aging (CLSA).
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Raina P, Wolfson C, Kirkland S, Griffith LE, Balion C, Cossette B, Dionne I, Hofer S, Hogan D, van den Heuvel ER, Liu-Ambrose T, Menec V, Mugford G, Patterson C, Payette H, Richards B, Shannon H, Sheets D, Taler V, Thompson M, Tuokko H, Wister A, Wu C, and Young L
- Published
- 2019
- Full Text
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79. Cohort Profile: The Canadian Longitudinal Study on Aging (CLSA).
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Raina P, Wolfson C, Kirkland S, Griffith LE, Balion C, Cossette B, Dionne I, Hofer S, Hogan D, van den Heuvel ER, Liu-Ambrose T, Menec V, Mugford G, Patterson C, Payette H, Richards B, Shannon H, Sheets D, Taler V, Thompson M, Tuokko H, Wister A, Wu C, and Young L
- Subjects
- Aged, Aged, 80 and over, Canada, Female, Humans, Life Style, Longitudinal Studies, Male, Middle Aged, Quality of Life, Aging physiology, Aging psychology
- Published
- 2019
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80. Independence, loss, and social identity: Perspectives on driving cessation and dementia.
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Sanford S, Rapoport MJ, Tuokko H, Crizzle A, Hatzifilalithis S, Laberge S, and Naglie G
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- Aged, Family psychology, Female, Humans, Male, Automobile Driving psychology, Dementia psychology, Social Identification
- Published
- 2019
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81. Normative comparison standards for measures of cognition in the Canadian Longitudinal Study on Aging (CLSA): Does applying sample weights make a difference?
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O'Connell ME, Tuokko H, Kadlec H, Griffith LE, Simard M, Taler V, Voll S, Thompson ME, Panyavin I, Wolfson C, Kirkland S, and Raina P
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- Aged, Aged, 80 and over, Bias, Canada, Data Interpretation, Statistical, Female, Humans, Longitudinal Studies, Male, Middle Aged, Models, Statistical, Reference Values, Cognition, Neuropsychological Tests, Research Design
- Abstract
Large-scale studies present the opportunity to create normative comparison standards relevant to populations. Sampling weights applied to the sample data facilitate extrapolation to the population of origin, but normative scores are often developed without the use of these sampling weights because the values derived from large samples are presumed to be precise estimates of the population parameter. The present article examines whether applying sample weights in the context of deriving normative comparison standards for measures of cognition would affect the distributions of regression-based normative data when using data from a large population-based study. To address these questions, we examined 3 cognitive measures from the Canadian Longitudinal Study on Aging tracking cohort (N = 14,110, Age 45-84 years at recruitment): Rey Auditory Verbal Learning Test - Immediate Recall, Animal Fluency, and the Mental Alternation Test. The use of sampling weights resulted in similar model parameter estimates to unweighted regression analyses and similar cumulative frequency distributions to the unweighted analyses. We randomly sampled progressively smaller subsets from the full database to test the hypothesis that sampling weights would help maintain the estimates from the full sample, but discovered that the weighted and unweighted estimates were similar and were less precise with smaller samples. These findings suggest that although use of sampling weights can help mitigate biases in data from sampling procedures, the application of weights to adjust for sampling biases do not appreciably impact the normative data, which lends support to the current practice in creation of normative data. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
- Published
- 2019
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82. Self-reported violations, errors and lapses for older drivers: Measuring the change in frequency of aberrant driving behaviours across five time-points.
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Koppel S, Stephens AN, Bédard M, Charlton JL, Darzins P, Stefano MD, Gagnon S, Gélinas I, Hua P, MacLeay L, Man-Son-Hing M, Mazer B, Myers A, Naglie G, Odell M, Porter MM, Rapoport MJ, Stinchcombe A, Tuokko H, Vrkjlan B, and Marshall S
- Subjects
- Age Distribution, Aged, Aged, 80 and over, Australia, Automobile Driving statistics & numerical data, Canada, Female, Humans, Longitudinal Studies, Male, Risk-Taking, Surveys and Questionnaires, Automobile Driving psychology, Self Report standards
- Abstract
The current study aimed to: 1. to confirm the 21-item, three-factor Driver Behaviour Questionnaire (DBQ) structure suggested by Koppel et al. (2018) within an independent sample of Canadian older drivers; 2. to examine whether the structure of the DBQ remained stable over a four-year period; 3. to conduct a latent growth analysis to determine whether older drivers' DBQ scores changed across time. Five hundred and sixty Canadian older drivers (males = 61.3%) from the Candrive/Ozcandrive longitudinal study completed the DBQ yearly for four years across five time-points that were approximately 12 months apart. In Year 1, the average age of the older drivers was 76.0 years (SD = 4.5 years; Range = 70-92 years). Findings from the study support the 21-item, three-factor DBQ structure suggested by Koppel and colleagues for an Australian sample of older drivers as being acceptable in an independent sample of Canadian older drivers. In addition, Canadian older drivers' responses to this version of the DBQ were stable across the five time-points. More specifically, there was very little change in older drivers' self-reported violations, and no significant change for self-reported errors or lapses. The findings from the current study add further support for this version of the DBQ as being a suitable tool for examining self-reported aberrant driving behaviours in older drivers. Future research should investigate the relationship between older drivers' self-reported aberrant driving behaviours and their performance on functional measures, their responses to other driving-related abilities and practice scales and/or questionnaires, as well their usual (or naturalistic) driving practices and/or performance on on-road driving tasks., (Copyright © 2018 Elsevier Ltd. All rights reserved.)
- Published
- 2019
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83. Miami Prospective Memory Test in the Canadian Longitudinal Study on Aging.
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Simard M, Rouleau I, Kadlec H, Taler V, Tuokko H, Voll S, O'Connell ME, Griffith LE, Wolfson C, Kirkland S, and Raina P
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- Aged, Aged, 80 and over, Aging, Canada, Female, Humans, Longitudinal Studies, Male, Middle Aged, Prospective Studies, Memory, Episodic, Neuropsychological Tests standards
- Abstract
Objective: The aim of this study was to verify the effect of age, education and sex on Miami Prospective Memory Test (MPMT) performance obtained at baseline of the Canadian Longitudinal Study on Aging (CLSA) by neurologically healthy French- and English-speaking subsamples of participants (N = 18,511)., Method: The CLSA is a nation-wide large epidemiological study with participants aged 45-85 years old at baseline. The MPMT is an event- and time-based measure of prospective memory, with scores of intention, accuracy and need for reminders, administered as part of the Comprehensive data collection. Participants who did not self-report any conditions that could impact cognition were selected, which resulted in 15,103 English- and 3408 French-speaking participants. The samples are stratified according to four levels of education and four age groups (45-54; 55-64; 65-74; 75+)., Results: There is a significant age effect for English- and French-speaking participants on the Event-based, Time-based, and Event- + Time-based scores of the MPMT. The effect of the education level was also demonstrated on the three MPMT scores in the English-speaking group. The score 'Intention to perform' was the most sensitive to the effect of age in both the English and French samples. Sex had no impact on performance on the MPMT., Conclusions: This study confirms the impact of age and level of education on this new prospective memory task. It informs future research with this measure including the development of normative data in French- and English-speaking Canadians on the Event-based and Time-based MPMT.
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- 2019
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84. An evidence-based approach to the creation of normative data: base rates of impaired scores within a brief neuropsychological battery argue for age corrections, but against corrections for medical conditions.
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O'Connell ME, Tuokko H, Voll S, Simard M, Griffith LE, Taler V, Wolfson C, Kirkland S, and Raina P
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- Age Factors, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Reference Values, Cognition Disorders diagnosis, Neuropsychological Tests standards
- Abstract
Objective: We detail a new approach to the creation of normative data for neuropsychological tests. The traditional approach to normative data creation is to make demographic adjustments based on observations of correlations between single neuropsychological tests and selected demographic variables. We argue, however, that this does not describe the implications for clinical practice, such as increased likelihood of misclassification of cognitive impairment, nor does it elucidate the impact on decision-making with a neuropsychological battery., Method: We propose base rate analyses; specifically, differential base rates of impaired scores between theoretical and actual base rates as the basis for decisions to create demographic adjustments within normative data. Differential base rates empirically describe the potential clinical implications of failing to create an appropriate normative group. We demonstrate this approach with data from a short telephone-administered neuropsychological battery given to a large, neurologically healthy sample aged 45-85 years old. We explored whether adjustments for age and medical conditions were warranted based on differential base rates of spuriously impaired scores., Conclusions: Theoretical base rates underestimated the frequency of impaired scores in older adults and overestimated the frequency of impaired scores in younger adults, providing an evidence base for the creation of age-corrected normative data. In contrast, the number of medical conditions (numerous cardiovascular, hormonal, and metabolic conditions) was not related to differential base rates of impaired scores. Despite a small correlation between number of medical conditions and each neuropsychological variable, normative adjustments for number of medical conditions does not appear warranted. Implications for creation of normative data are discussed.
- Published
- 2017
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85. Functional disability and social participation restriction associated with chronic conditions in middle-aged and older adults.
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Griffith LE, Raina P, Levasseur M, Sohel N, Payette H, Tuokko H, van den Heuvel E, Wister A, Gilsing A, and Patterson C
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- Aged, Aged, 80 and over, Canada, Cross-Sectional Studies, Female, Humans, Independent Living, Male, Middle Aged, Activities of Daily Living, Chronic Disease epidemiology, Disabled Persons statistics & numerical data, Social Participation
- Abstract
Background: We examine the population impact on functional disability and social participation of physical and mental chronic conditions individually and in combination., Methods: Cross-sectional, population-based data from community-dwelling people aged 45 years and over living in the 10 Canadian provinces in 2008-2009 were used to estimate the population attributable risk (PAR) for functional disability in basic (ADL) and instrumental (IADL) activities of daily living and social participation restrictions for individual and combinations of chronic conditions, stratified by age and gender, after adjusting for confounding variables., Results: Five chronic conditions (arthritis, depression, diabetes, heart disease and eye disease) made the largest contributions to ADL-related and IADL-related functional disability and social participation restrictions, with variation in magnitude and ranking by age and gender. While arthritis was consistently associated with higher PARs across gender and most age groups, depression, alone and in combination with the physical chronic conditions, was associated with ADL and IADL disability as well as social participation restrictions in the younger age groups, especially among women. Compared to women, the combinations of conditions associated with higher PARs in men more often included heart disease and diabetes., Conclusions: Our findings suggest that in community-dwelling middle-aged and older adults, the impact of combinations of mental and physical chronic conditions on functional disability and social participation restriction is substantial and differed by gender and age. Recognising the differences in the drivers of PAR by gender and age group will ultimately increase the efficiency of clinical and public health interventions., (Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.)
- Published
- 2017
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86. Cognitive measures in the Canadian Longitudinal Study on Aging.
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Tuokko H, Griffith LE, Simard M, and Taler V
- Subjects
- Aged, Aged, 80 and over, Canada, Female, Humans, Language, Longitudinal Studies, Male, Mental Recall, Middle Aged, Verbal Learning, Aging psychology, Cognition, Neuropsychological Tests
- Abstract
Objective: We describe the implementation of cognitive measures within the Canadian Longitudinal Study on Aging (CLSA), a nationwide, epidemiological study of aging, and relate CLSA Tracking cohort data (n over 20,000) to previous studies using these measures., Method: CLSA participants (aged 45-85, n over 50,000) provided demographic, social, physical/clinical, psychological, economic, and health service utilization information relevant to health and aging through telephone interviews (Tracking cohort, n over 20,000) or in-person (i.e. Comprehensive cohort, n over 30,000) in both official languages (i.e. English, French). Cognitive measures included: the Rey Auditory Verbal Learning Test (RAVLT) - Trial 1 and five-minute delayed recall; Animal Fluency (AF), the Mental Alternation Test (MAT) (both cohorts); Controlled Oral Word Association Test, Stroop Test, Prospective Memory Test, and Choice reaction times (Comprehensive Cohort)., Results: Performance on the RAVLT Trial 1 and AF were very similar to comparable groups studied previously; CLSA sample sizes were far larger. Within the CLSA Tracking cohort, main effects of age and language were observed for all cognitive measures except RAVLT delayed recall. Interaction effects (language × age) were observed for AF., Conclusion: This preliminary examination of the CLSA Tracking cognitive measures lends support to their use in large studies of aging. The CLSA has the potential to provide the 'best' comparison data for adult Canadians generated to date and may also be applicable more broadly. Future studies examining relations among the psychological, biological, health, lifestyle, and social measures within the CLSA will make unique contributions to understanding aging.
- Published
- 2017
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87. Older Driver Safety: A Survey of Psychologists' Attitudes, Knowledge, and Practices.
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Love J and Tuokko H
- Subjects
- Aged, Aged, 80 and over, Canada, Female, Humans, Male, Middle Aged, Surveys and Questionnaires, Aging psychology, Attitude of Health Personnel, Automobile Driving psychology, Clinical Competence, Cognitive Dysfunction psychology, Dementia psychology, Practice Patterns, Physicians', Psychology
- Abstract
Using an online survey, we examined the knowledge, attitudes, and practices with respect to older driver safety concerns of clinical psychologists from across Canada who self-identified as working with at least some drivers over 60 years of age. Eighty-four psychologists completed the survey, and many were aware of the issues relevant to older driver safety, although only about half reported that assessing fitness to drive was an important issue in their practice. The majority (75%) reported that they would benefit from education concerning evaluation of fitness to drive. The primary recommendation emerging from this investigation is to increase efforts to inform and educate psychologists about driving-related assessment and regulatory issues in general, and specifically with respect to older adults. As the population ages, it is of growing importance for all health care providers to understand the influence of mental health conditions-including cognitive impairment and dementia-on driving skills.
- Published
- 2016
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88. Attitudes: Mediators of the Relation between Health and Driving in Older Adults.
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Tuokko H, Sukhawathanakul P, Walzak L, Jouk A, Myers A, Marshall S, Naglie G, Rapoport M, Vrkljan B, Porter M, Man-Son-Hing M, Mazer B, Korner-Bitensky N, Gélinas I, and Bédard M
- Subjects
- Aged, Aged, 80 and over, Aging, Avoidance Learning, Female, Humans, Longitudinal Studies, Male, Self Report, Self-Control, Attitude to Health, Automobile Driving psychology, Health Status
- Abstract
We examined the relations between perceived health (e.g., self-perceived health status) and driving self-regulatory practices (e.g., frequency of driving, avoiding challenging driving situations) as mediated by driving attitudes and perceptions (i.e., driving comfort, positive and negative attitudes towards driving) in data collected for 928 drivers aged 70 and older enrolled in the Candrive II study. We observed that specific attitudes towards driving (e.g., driving comfort, negative attitudes towards driving) mediate the relations between health symptoms and self-regulatory driving behaviours at baseline and over time. Only negative attitudes towards driving fully mediated the relationships between changes in perceived health symptoms and changes in driving behavior. Perceived health symptoms apparently influence the likelihood of avoiding challenging driving situations through both initial negative attitudes towards driving as well as changes in negative attitudes over time. Understanding influences on self-regulatory driving behaviours will be of benefit when designing interventions to enhance the safety of older drivers.
- Published
- 2016
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89. Psychosocial Constructs as Possible Moderators of Self-Reported Driving Restrictions.
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Jouk A, Sukhawathanakul P, Tuokko H, Myers A, Naglie G, Vrkljan B, Porter MM, Rapoport M, Marshall S, Mazer B, Man-Son-Hing M, Korner-Bitensky N, Gélinas I, and Bédard M
- Subjects
- Aged, Aged, 80 and over, Analysis of Variance, Attitude, Awareness, Female, Humans, Male, Prospective Studies, Self-Control psychology, Time Factors, Age Factors, Aging, Automobile Driving psychology, Self Report
- Abstract
To date, associations between psychosocial driving variables and behaviour have been examined only cross-sectionally. Using three waves of data collected annually from 928 older drivers (mean age = 76.21 years; 62% male) enrolled in the Candrive II cohort, we examined in this study whether changes in attitudes and perceptions towards driving (decisional balance and day and night driving comfort) were associated with changes in older adults' reported restrictions in driving practices and perceived driving abilities. Multi-level models revealed that older adults who showed an increase in negative attitudes towards driving over time were more likely to report more-restricted practices (greater avoidance of challenging driving situations) and perceived declines in driving abilities compared to individuals whose attitudes towards driving remained stable across two years. This work supports previous findings and offers a new understanding of how attitudes relate to driving perceptions (e.g., comfort) and self-regulation in older adults over time.
- Published
- 2016
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90. CIHR Candrive Cohort Comparison with Canadian Household Population Holding Valid Driver's Licenses.
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Gagnon S, Marshall S, Kadulina Y, Stinchcombe A, Bédard M, Gélinas I, Man-Son-Hing M, Mazer B, Naglie G, Porter MM, Rapoport M, Tuokko H, and Vrkljan B
- Subjects
- Aged, Aged, 80 and over, Canada, Cohort Studies, Family Characteristics, Female, Health Status, Humans, Licensure statistics & numerical data, Longitudinal Studies, Male, Sample Size, Self Report, Automobile Driving statistics & numerical data, Research Design standards
- Abstract
We investigated whether convenience sampling is a suitable method to generate a sample of older drivers representative of the older-Canadian driver population. Using equivalence testing, we compared a large convenience sample of older drivers (Candrive II prospective cohort study) to a similarly aged population of older Canadian drivers. The Candrive sample consists of 928 community-dwelling older drivers from seven metropolitan areas of Canada. The population data was obtained from the Canadian Community Health Survey - Healthy Aging (CCHS-HA), which is a representative sample of older Canadians. The data for drivers aged 70 and older were extracted from the CCHS-HA database, for a total of 3,899 older Canadian drivers. Two samples were demonstrated as equivalent on socio-demographic, health, and driving variables that we compared, but not on driving frequency. We conclude that convenience sampling used in the Candrive study created a fairly representative sample of Canadian older drivers, with a few exceptions.
- Published
- 2016
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91. Cognitive Performance, Driving Behavior, and Attitudes over Time in Older Adults.
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Rapoport MJ, Sukhawathanakul P, Naglie G, Tuokko H, Myers A, Crizzle A, Korner-Bitensky N, Vrkljan B, Bédard M, Porter MM, Mazer B, Gélinas I, Man-Son-Hing M, and Marshall S
- Subjects
- Aged, Aged, 80 and over, Attitude, Avoidance Learning, Female, Humans, Longitudinal Studies, Male, Multivariate Analysis, Self Report, Self-Control psychology, Aging physiology, Automobile Driving psychology, Cognition physiology, Mental Status and Dementia Tests statistics & numerical data
- Abstract
We hypothesized that changes over time in cognitive performance are associated with changes in driver perceptions, attitudes, and self-regulatory behaviors among older adults. Healthy older adults (n = 928) underwent cognitive assessments at baseline with two subsequent annual follow-ups, and completed scales regarding their perceptions, attitudes, and driving behaviours. Multivariate analysis showed small but statistically significant relationships between the cognitive tests and self-report measures, with the largest magnitudes between scores on the Trails B cognitive task (seconds), perceptions of driving abilities (β = -0.32), and situational driving avoidance (β = 0.55) (p < 0.05). Cognitive slowing and executive dysfunction appear to be associated with modestly lower perceived driving abilities and more avoidance of driving situations over time in this exploratory analysis.
- Published
- 2016
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92. Factors influencing discrepancies in self-reported memory and performance on memory recall in the Canadian Community Health Survey-Healthy Aging, 2008-09.
- Author
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Sohel N, Tuokko H, Griffith L, and Raina P
- Subjects
- Age Factors, Aged, Aged, 80 and over, Alcohol Drinking adverse effects, Alcohol Drinking psychology, Canada epidemiology, Chi-Square Distribution, Female, Health Surveys, Humans, Learning, Life Style, Linear Models, Loneliness, Male, Memory Disorders diagnosis, Memory Disorders epidemiology, Middle Aged, Multivariate Analysis, Neuropsychological Tests, Predictive Value of Tests, Reproducibility of Results, Risk Factors, Socioeconomic Factors, Aging psychology, Memory Disorders psychology, Mental Recall, Self Report
- Abstract
Objective: the objectives of this study were: (i) to estimate the rate of discrepancy between participant single-item self-reports of good memory and poor performance on a list-learning task and (ii) to identify the factors including age, gender and health status that influence these discrepant classifications., Study Design and Settings: in total, 14,172 individuals, aged 45-85, were selected from the 2008-09 Canadian Community Health Survey on Healthy Aging. We examined the individual characteristics of participants with and without discrepancies between memory self-reports and performance with a generalised linear model, adjusting for potential covariates., Results: the mean age of respondents was 62.9 years with 56.7% being female, 53.8% having post-secondary graduation and 83% being born in Canada. Higher discrepant classification rates we observed for younger people (6.77 versus 3.65 for lowest and highest group), female (5.90 versus 3.68) and with higher education (6.17 versus 3.52). Discrepant classification rates adjusted with all covariates were higher for those without chronic diseases (5.37 [95% Confidence Interval (CI): 4.16, 6.90] versus 4.05 95% CI: 3.38, 4.86; P = 0.0127), those who did not drink alcohol (5.87 95% CI: 4.69, 7.32 versus 3.70 95% CI: 3.00, 4.55; P < 0.0001), lonely participants (5.45 95% CI: 4.20, 7.04 versus 3.99 95% CI: 3.36, 4.77; P = 0.0081) and bilingual participants (5.67 95% CI: 4.18, 7.64 versus 3.83 95% CI: 3.27, 4.50; P = 0.0102)., Conclusion: the findings of this study suggest that the self-reported memory and memory performance differ in a substantial proportion of the population. Therefore, relying on a self-reported memory status may not accurately capture those experiencing memory difficulties., (© The Author 2015. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
- Published
- 2016
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93. Measuring Driving-Related Attitudes Among Older Adults: Psychometric Evidence for the Decisional Balance Scale Across Time and Gender.
- Author
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Sukhawathanakul P, Tuokko H, Rhodes RE, Marshall SC, Charlton J, Koppel S, Gélinas I, Naglie G, Mazer B, Vrkljan B, Myers A, Man-Son-Hing M, Bédard M, Rapoport M, Korner-Bitensky N, and Porter MM
- Subjects
- Aged, Humans, Surveys and Questionnaires, Attitude, Automobile Driving psychology, Psychometrics methods
- Abstract
Purpose of the Study: The Decisional Balance Scale (DBS) was developed to assess older adults' attitudes related to driving and includes both intrapersonal and interpersonal motivations for driving. This study examined the psychometric properties of the DBS ratings across 3 time points in a sample of 928 older drivers who participated in the Canadian Driving Research Initiative for Vehicular Safety in the Elderly (Candrive)., Design and Methods: Measurement invariance of the DBS was assessed longitudinally and across gender., Results: Confirmatory factor analyses revealed that a two-factor model (positive and negative attitudes) for both driving beliefs related to the self and other provided a good fit to the data at each time point. Measurement invariance was supported across time and gender. Significant associations between the DBS factor scores and other driving measures (e.g., perceived driving ability and self-regulatory driving practices) provided evidence of convergent validity., Implications: The DBS appears to be a robust instrument for measuring attitudes toward driving and is recommended for continued use in future research on driving behaviors with older adults., (© The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2015
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94. An international study of the quality of national-level guidelines on driving with medical illness.
- Author
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Rapoport MJ, Weegar K, Kadulina Y, Bédard M, Carr D, Charlton JL, Dow J, Gillespie IA, Hawley CA, Koppel S, McCullagh S, Molnar F, Murie-Fernández M, Naglie G, O'Neill D, Shortt S, Simpson C, Tuokko HA, Vrkljan BH, and Marshall S
- Subjects
- Evidence-Based Medicine, Humans, International Cooperation, Observer Variation, Risk Assessment, Acute Disease, Automobile Driving, Chronic Disease, Practice Guidelines as Topic standards
- Abstract
Background: Medical illnesses are associated with a modest increase in crash risk, although many individuals with acute or chronic conditions may remain safe to drive, or pose only temporary risks. Despite the extensive use of national guidelines about driving with medical illness, the quality of these guidelines has not been formally appraised., Aim: To systematically evaluate the quality of selected national guidelines about driving with medical illness., Design: A literature search of bibliographic databases and Internet resources was conducted to identify the guidelines, each of which was formally appraised., Methods: Eighteen physicians or researchers from Canada, Australia, Ireland, USA and UK appraised nine national guidelines, applying the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument., Results: Relative strengths were found in AGREE II scores for the domains of scope and purpose, stakeholder involvement and clarity of presentation. However, all guidelines were given low ratings on rigour of development, applicability and documentation of editorial independence. Overall quality ratings ranged from 2.25 to 5.00 out of 7.00, with modifications recommended for 7 of the guidelines. Intra-class coefficients demonstrated fair to excellent appraiser agreement (0.57-0.79)., Conclusions: This study represents the first systematic evaluation of national-level guidelines for determining medical fitness to drive. There is substantive variability in the quality of these guidelines, and rigour of development was a relative weakness. There is a need for rigorous, empirically derived guidance for physicians and licensing authorities when assessing driving in the medically ill., (© The Author 2015. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
- Published
- 2015
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95. Interview with Dr Holly Tuokko, 22 March 2013.
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Tuokko H, Peters KR, and Katz S
- Subjects
- Aging, Alzheimer Disease classification, Alzheimer Disease diagnosis, Alzheimer Disease history, Behavior physiology, Biomedical Research history, Canada, Cognitive Dysfunction classification, Cognitive Dysfunction diagnosis, History, 20th Century, History, 21st Century, Humans, Neuropsychological Tests standards, Activities of Daily Living, Cognitive Dysfunction history, Neurology history
- Published
- 2015
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96. Just the facts: changes in older driver attitudes after exposure to educational interventions.
- Author
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Tuokko H, Rhodes RE, Love J, Cloutier D, Jouk A, and Schoklitsch A
- Subjects
- Aged, Aged, 80 and over, Drama, Female, Follow-Up Studies, Humans, Male, Mass Media, Power, Psychological, Program Evaluation, Attitude, Automobile Driving education, Automobile Driving psychology
- Abstract
Objectives: To examine the change in cognitive processing as measured by consciousness raising and attitudes toward driving following educational interventions for older adults., Methods: Older adults who viewed a research-based applied theater production about older driver safety (n = 110) were compared to those who were exposed to a print-based publication available to all drivers (n = 100)., Results: After viewing the play developed with input from older adults and others, older adult viewers' attitudes toward driving shifted in a manner consistent with an increased openness or willingness to consider changing their driving behavior. Conversely, after reading the print-based materials, the older adults felt more empowered to continue drive., Conclusions: Demonstrating that an intervention that takes into account the views of older drivers can lead to attitudinal outcomes that differ from those achieved with typical "just the facts" programs is an important step in understanding how program content and format affect outcomes. Future interdisciplinary work such as this may enhance our capabilities to understand more about the processes involved in influencing change in attitudes and behaviors.
- Published
- 2015
- Full Text
- View/download PDF
97. Herpes simplex virus type 1 genital herpes in young women: current trend in Northern Finland.
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Tuokko H, Bloigu R, and Hukkanen V
- Subjects
- Adolescent, Female, Finland epidemiology, Herpes Genitalis virology, Humans, Sexually Transmitted Diseases, Viral virology, Young Adult, Herpes Genitalis epidemiology, Herpesvirus 1, Human isolation & purification, Public Health, Sexually Transmitted Diseases, Viral epidemiology
- Published
- 2014
- Full Text
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98. Measurement equivalence of neuropsychological tests across education levels in older adults.
- Author
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Brewster PW, Tuokko H, and MacDonald SW
- Subjects
- Aged, Aged, 80 and over, Factor Analysis, Statistical, Female, Humans, Longitudinal Studies, Male, Mental Status Schedule, Models, Statistical, Psychometrics, Retrospective Studies, Aging, Cognition Disorders diagnosis, Cognitive Reserve physiology, Educational Status, Neuropsychological Tests
- Abstract
Objective: The objective was to determine whether neuropsychological tests provide an equivalent measure of the same psychological constructs in older adults with low versus higher levels of education., Method: Confirmatory factor analysis was used to evaluate the fit of a three-factor model (Verbal Ability, Visuospatial Ability, Long-Term Retention) to scores from the neuropsychological battery of the Canadian Study of Health and Aging (CSHA). Measurement equivalence of the model across lower educated (LE; ≤8 years) and higher educated (HE; ≥9 years) participants was evaluated using invariance testing., Results: The measurement model demonstrated adequate fit across LE and HE samples but the loadings of the 11 tests onto the three factors could not be constrained equally across groups. Animal Fluency and the Token Test were identified as noninvariant tests of Verbal Ability that, when freed from constraints, produced a partial metric invariance model. Scalar invariance testing identified the Buschke Cued Recall Test and Block Design as measures with invariant factor loadings but noninvariant intercepts. Analyses were replicated in age- and sex-matched subsamples., Conclusions: Metric and scalar invariance across HE and LE samples was achieved for seven of the 11 tests in the CSHA battery. Animal Fluency and the Token Test were noninvariant measures of Verbal Ability, suggesting that cognitive processes underlying performance on these tests may vary as a function of education. In addition, scores from Block Design and the Buschke Cued Recall Test were observed to differ in their scale of measurement between HE and LE examinees.
- Published
- 2014
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- View/download PDF
99. It is premature to test older drivers with the SIMARD-MD.
- Author
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Bédard M, Marshall S, Man-Son-Hing M, Weaver B, Gélinas I, Korner-Bitensky N, Mazer B, Naglie G, Porter MM, Rapoport MJ, Tuokko H, and Vrkljan B
- Subjects
- Aged, Aged, 80 and over, Canada, Cohort Studies, Cross-Sectional Studies, Female, Humans, Licensure standards, Linear Models, Male, Mass Screening instrumentation, Neuropsychological Tests, Predictive Value of Tests, Psychometrics instrumentation, Accidents, Traffic prevention & control, Automobile Driving standards, Cognition Disorders diagnosis
- Abstract
Background: A new tool, the SIMARD-MD, has been proposed to help physicians identify cognitively impaired drivers who may be unfit to drive, but little empirical evidence is available to justify its use. We analyzed data from a cohort of older Canadian drivers who had undergone cognitive testing to: (1) correlate the SIMARD-MD with other tools that measure cognition (e.g., trail-making test), (2) identify how many drivers, using published cut-offs on the SIMARD-MD, would be recommended to lose their license, or be considered fit to drive, or be required to undergo further driving assessment, and (3) determine if the SIMARD-MD is biased by level of education as many cognitive tools are., Methods: Cross-sectional data from 841 drivers aged 70 and over from seven Canadian sites who are enrolled in a 5-year cohort study were used for the analyses. Scores on the SIMARD-MD were correlated with scores on the other cognitive measures. The recommendations that would be made based on the SIMARD-MD scores were based on published cut-off values suggested by the authors of the tool. The impact of education status was examined using linear regression controlling for age., Results: Correlations between the SIMARD-MD and other cognitive measures ranged from .15 to .86. Using published cut-off scores, 21 participants (2.5%) would have been recommended to relinquish their licenses, 428 (50.9%) would have been deemed fit to drive, and 392 (46.6%) would have been required to undergo further testing. We found a difference of 8.19 points (95% CI=4.99, 11.40, p<.001) in favor of drivers with post-secondary education versus those without, representing over 11% of the mean score., Discussion: The SIMARD-MD is unlikely to be valuable to clinicians because it lacks sufficient precision to provide clear recommendations about fitness-to-drive. Recommendations based solely on the SIMARD-MD may place many seniors at risk of losing their transportation mobility or incurring unnecessary stress and costs to prove they are safe to drive. Furthermore, the education bias may create an unwanted structural inequity. Hence, adoption of the SIMARD-MD as a tool to determine fitness-to-drive appears premature., (Copyright © 2013 Elsevier Ltd. All rights reserved.)
- Published
- 2013
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100. The impact of subclinical sleep problems on self-reported driving patterns and perceived driving abilities in a cohort of active older drivers.
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Hickey AJ, Weegar K, Kadulina Y, Gagnon S, Marshall S, Myers A, Tuokko H, Bédard M, Gélinas I, Man-Son-Hing M, Mazer B, Naglie G, Porter M, Rapoport M, and Vrkljan B
- Subjects
- Aged, Aged, 80 and over, Automobile Driving psychology, Benzodiazepines therapeutic use, Canada epidemiology, Cholinergic Antagonists therapeutic use, Cohort Studies, Cross-Sectional Studies, Depression epidemiology, Depression psychology, Female, Humans, Male, Regression Analysis, Sleep Wake Disorders psychology, Surveys and Questionnaires, Automobile Driving statistics & numerical data, Sleep Wake Disorders epidemiology
- Abstract
The present study sought to investigate the influence of subclinical sleep disturbances on driving practices and driver perceptions in a large cohort of healthy older drivers. Participants from the Candrive II prospective cohort study were investigated. Self-reported measures of sleep problems were used to determine the influence of sleep disturbance on self-reported driving practices and perceived driving abilities, as measured by the Situational Driving Frequency, Situational Driving Avoidance, and Perceived Driving Abilities scales. Hierarchical regression analyses were used to estimate whether mild self-reported sleep problems were predictive of driving restrictions and perceived abilities, while controlling for a variety of health-related factors and demographic variables known to mediate sleep problems or to impact driving. Cross-sectional analysis of baseline data from the Candrive II study suggests that subclinical sleep problems do not significantly influence self-reported driving patterns or perceived driving abilities in older drivers once control variables are considered. The relationship between sleep problems, driving frequency, avoidance and perceived abilities is better explained by mediating demographic, health, and cognitive factors. Further research examining sleep disturbances and driving should include objective measures of driving practices (exposure, patterns) and outcomes (crashes, violations) and should take in consideration the severity of sleep problems., (Copyright © 2013. Published by Elsevier Ltd.)
- Published
- 2013
- Full Text
- View/download PDF
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