443 results on '"Tomchick, Diana R."'
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52. Molecular Discrimination between Two Conformations of Sphingomyelin in Plasma Membranes
53. A protein catalytic framework with an N-terminal nucleophile is capable of self-activation
54. Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
55. Trypanosomatid Deoxyhypusine Synthase Activity Is Dependent on Shared Active-Site Complementation between Pseudoenzyme Paralogs
56. Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265
57. Protein AMPylation by an Evolutionarily Conserved Pseudokinase
58. Insights into neurotransmitter release from the structure of Munc13-1 C1C2BMUN
59. Bile salt receptor complex activates a pathogenic type III secretion system - 'Diffraction Methods in Structural Biology' Gordon Research Conference poster, 2016
60. Changes at the KinA PAS-A dimerization interface influence histidine kinase function
61. Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel
62. Interactions of substrates at the surface of P450s can greatly enhance substrate potency
63. Crystal structure of the RIM1[alpha] [C.sub.2]B domain at 1.7 Angstrom resolution
64. Crystal structure of the RIM2 C2A-domain at 1.4-angstrom resolution
65. SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK
66. Author response: SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK
67. Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C 2 A domain in asynchronous neurotransmitter release
68. Opportunities to communicate results from challenging non-routine macromolecular structures in open-access online journals
69. Mechanistic insights into neurotransmitter release and presynaptic 3 plasticity from the crystal structure of Munc13-1 C1C2BMUN
70. Allostery in motion: Trypanosoma brucei enzyme brought to life by a dead paralog
71. Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein fromTreponema pallidum
72. Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN
73. Author response: Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN
74. Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog
75. Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution
76. Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265.
77. Author response: Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog
78. A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria
79. Bile salt receptor complex activates a pathogenic type III secretion system
80. Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity
81. Author response: Bile salt receptor complex activates a pathogenic type III secretion system
82. Structural Basis and IP6 Requirement for Pds5-Dependent Cohesin Dynamics
83. Pathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches
84. Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution
85. Molecular insights into the enzymatic diversity of flavin‐trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm
86. A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
87. Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein
88. Evolution of Substrate Specificity within a Diverse Family of β/α-Barrel-fold Basic Amino Acid Decarboxylases: X-RAY STRUCTURE DETERMINATION OF ENZYMES WITH SPECIFICITY FOR l-ARGININE AND CARBOXYNORSPERMIDINE*
89. Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution
90. Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
91. SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
92. Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein from Treponema pallidum.
93. Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.
94. Substrate-Specific Activation of the Mitotic Kinase Bub1 through Intramolecular Autophosphorylation and Kinetochore Targeting
95. Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion
96. Identification of Lysine Residues in the Borrelia burgdorferi DbpA Adhesin Required for Murine Infection
97. Re-examining how complexin inhibits neurotransmitter release
98. Author response: Re-examining how complexin inhibits neurotransmitter release
99. Structure and Ca2+-Binding Properties of the Tandem C2 Domains of E-Syt2
100. The Bacterial Effector VopL Organizes Actin into Filament-like Structures
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