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434 results on '"Tang, Yi-Da"'

68. Association Between Thyroid Dysfunction and Incidence of Atrial Fibrillation in Patients With Hypertrophic Obstructive Cardiomyopathy

Author

Meng, Xiangbin, primary, Wang, Xu-Liang, additional, Zhang, Zhi-yuan, additional, Zhang, Kuo, additional, Gao, Jun, additional, Zheng, Ji-lin, additional, Wang, Jing-Jia, additional, Liu, Yu-peng, additional, Yang, Jie, additional, Li, Chen, additional, Zheng, Yi-Tian, additional, Shao, Chunli, additional, Wang, Wen-Yao, additional, and Tang, Yi-Da, additional

Published
2022
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71. Long-Term Outcomes for Chinese COPD Patients After PCI: A Propensity Score Matched, Double-Cohort Study

Author

Zheng, Yitian, primary, Qi, Yu, additional, Seery, Samuel, additional, Wang, Wenyao, additional, Zhao, Wei, additional, Shen, Tao, additional, Zhou, Lequn, additional, Yang, Jie, additional, Li, Chen, additional, Wang, Xuliang, additional, Gao, Jun, additional, Meng, Xiangbin, additional, Dong, Erdan, additional, and Tang, Yi-Da, additional

Published
2022
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72. Long-Term Outcomes for Chinese COPD Patients After PCI:A Propensity Score Matched, Double-Cohort Study

Author

Zheng, Yitian, Qi, Yu, Seery, Samuel, Wang, Wenyao, Zhao, Wei, Shen, Tao, Zhou, Lequn, Yang, Jie, Li, Chen, Wang, Xuliang, Gao, Jun, Meng, Xiangbin, Dong, Erdan, Tang, Yi-Da, Zheng, Yitian, Qi, Yu, Seery, Samuel, Wang, Wenyao, Zhao, Wei, Shen, Tao, Zhou, Lequn, Yang, Jie, Li, Chen, Wang, Xuliang, Gao, Jun, Meng, Xiangbin, Dong, Erdan, and Tang, Yi-Da

Abstract

Objectives: The aim of this study was to analyze long-term outcomes of Chinese coronary artery disease (CAD) patients with (and without) chronic obstructive pulmonary disease (COPD) after percutaneous coronary intervention (PCI). Background: Chronic obstructive pulmonary disease is a chronic condition which often develops in conjunction with CAD. PCI is a core therapy for CAD, although we still need to understand CAD-COPD outcomes and to identify factors that influence prognoses, across ethnicities. Methods: This double-cohort study involved 12,343 Chinese CAD patients who received PCI. Baseline characteristics were collected in two independent, specialty centers. Propensity-score matching was performed to control confounding factors, using a nearest neighbor matching method within a 0.02 caliper and on a propensity score scale of 0.1 for each center. Comorbid CAD-COPD cases were compared to non-COPD patients in terms of major adverse cardiac events (MACEs). Results: Patients with COPD were generally older than those without COPD (65.4 ± 9.2 vs. 58.2 ± 10.3, p < 0.001). There were no significant differences in the end points between COPD and non-COPD groups after PCI (All p > 0.05); however, the incidence of MACEs increased after 450 days. Further subgroup analysis suggests that COPD is approximately four times more prevalent among those aged over 75 years (HR, 3.818; 95%CI, 1.10–13.29; p = 0.027) and those aged below 55 years (HR = 4.254; 95% CI, 1.55–11.72; p = 0.003). Conclusion: Having COPD does not appear to have a significant impact on CAD outcomes 2 years after PCI, and beyond. However, an increasing number of MACEs was observed after 450 days, which suggests that there may be a double-stage effect of COPD on PCI prognosis. There is a need for focused comorbidity management, specifically for those aged below 55 years and above 75 years.

Published
2022

73. Long-Term Outcomes for Chinese COPD Patients After PCI : A Propensity Score Matched, Double-Cohort Study

Author

Zheng, Yitian, Qi, Yu, Seery, Samuel, Wang, Wenyao, Zhao, Wei, Shen, Tao, Zhou, Lequn, Yang, Jie, Li, Chen, Wang, Xuliang, Gao, Jun, Meng, Xiangbin, Dong, Erdan, Tang, Yi-Da, Zheng, Yitian, Qi, Yu, Seery, Samuel, Wang, Wenyao, Zhao, Wei, Shen, Tao, Zhou, Lequn, Yang, Jie, Li, Chen, Wang, Xuliang, Gao, Jun, Meng, Xiangbin, Dong, Erdan, and Tang, Yi-Da

Abstract

Objectives: The aim of this study was to analyze long-term outcomes of Chinese coronary artery disease (CAD) patients with (and without) chronic obstructive pulmonary disease (COPD) after percutaneous coronary intervention (PCI). Background: Chronic obstructive pulmonary disease is a chronic condition which often develops in conjunction with CAD. PCI is a core therapy for CAD, although we still need to understand CAD-COPD outcomes and to identify factors that influence prognoses, across ethnicities. Methods: This double-cohort study involved 12,343 Chinese CAD patients who received PCI. Baseline characteristics were collected in two independent, specialty centers. Propensity-score matching was performed to control confounding factors, using a nearest neighbor matching method within a 0.02 caliper and on a propensity score scale of 0.1 for each center. Comorbid CAD-COPD cases were compared to non-COPD patients in terms of major adverse cardiac events (MACEs). Results: Patients with COPD were generally older than those without COPD (65.4 ± 9.2 vs. 58.2 ± 10.3, p < 0.001). There were no significant differences in the end points between COPD and non-COPD groups after PCI (All p > 0.05); however, the incidence of MACEs increased after 450 days. Further subgroup analysis suggests that COPD is approximately four times more prevalent among those aged over 75 years (HR, 3.818; 95%CI, 1.10–13.29; p = 0.027) and those aged below 55 years (HR = 4.254; 95% CI, 1.55–11.72; p = 0.003). Conclusion: Having COPD does not appear to have a significant impact on CAD outcomes 2 years after PCI, and beyond. However, an increasing number of MACEs was observed after 450 days, which suggests that there may be a double-stage effect of COPD on PCI prognosis. There is a need for focused comorbidity management, specifically for those aged below 55 years and above 75 years.

Published
2022

74. Elevated HsCRP in Chronic Obstructive Pulmonary Disease: A Prospective Study of Long-Term Outcomes After Percutaneous Coronary Intervention

Author

Zheng,Yitian, Qi,Yu, Seery,Samuel, Yang,Jie, Li,Chen, Wang,Wenyao, Gao,Jun, Meng,Xiangbin, Shao,Chunli, Tang,Yi-Da, Zheng,Yitian, Qi,Yu, Seery,Samuel, Yang,Jie, Li,Chen, Wang,Wenyao, Gao,Jun, Meng,Xiangbin, Shao,Chunli, and Tang,Yi-Da

Abstract

Yitian Zheng,1– 3,&ast; Yu Qi,1,&ast; Samuel Seery,4,5 Jie Yang,2,3 Chen Li,2,3 Wenyao Wang,1 Jun Gao,1 Xiangbin Meng,1 Chunli Shao,1 Yi-Da Tang1 1Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing, People’s Republic of China; 2Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; 3Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; 4School of Humanities and Social Sciences, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, People’s Republic of China; 5Faculty of Health and Medicine, Division of Health Research, Lancaster University, Lancaster, UK&ast;These authors contributed equally to this workCorrespondence: Yi-Da Tang, Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education; Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing, 100191, People’s Republic of China, Email tangyida@bjmu.edu.cnObjective: Anti-inflammatory therapies are reported to have additional benefits beyond lipid control for patients with cardiovascular disease. However, no study has focused on the relationship between inflammation status and long-term outcomes for chronic obstructive pulmonary disease (COPD) patients, after percutaneous coronary intervention (PCI).Methods: 277 COPD-PCI

Published
2022

75. Genetically Determined Lifestyle and Cardiometabolic Risk Factors Mediate the Association of Genetically Predicted Age at Menarche With Genetic Predisposition to Myocardial Infarction: A Two-Step, Two-Sample Mendelian Randomization Study

Author

Zheng, Jilin, primary, Chen, Ken, additional, Huang, Tao, additional, Shao, Chunli, additional, Li, Ping, additional, Wang, Jingjia, additional, Wang, Wenyao, additional, Zhang, Kuo, additional, Meng, Xiangbin, additional, Gao, Jun, additional, Wang, Xuliang, additional, Liu, Yupeng, additional, Song, Jingjing, additional, Dong, Eran, additional, and Tang, Yi-Da, additional

Published
2022
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80. CHA2DS2-VASc score as a prognostic indicator in patients with atrial fibrillation undergoing coronary stenting

Author

ZHENG, JIAN-YONG, primary, LI, DONG-TAO, additional, QIU, YI-GANG, additional, HUANG, YI-XIONG, additional, XU, ZHENG-MING, additional, ZHAO, LI, additional, CHEN, YU, additional, CAO, YI, additional, TANG, YI-DA, additional, GUO, CHENG-JUN, additional, MA, ZHI-MIN, additional, WU, YONG-QUAN, additional, JIAO, YAN, additional, and LI, TIAN-CHANG, additional

Published
2022
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89. Additional file 1 of Association of healthy lifestyle including a healthy sleep pattern with incident type 2 diabetes mellitus among individuals with hypertension

Author

Song, Zimin, Yang, Ruotong, Wang, Wenxiu, Huang, Ninghao, Zhuang, Zhenhuang, Han, Yuting, Qi, Lu, Xu, Ming, Tang, Yi-da, and Huang, Tao

Abstract

Additional file 1: Table S1. Disease codes for Metabolic diseases of Type 2 Diabetes, Hypertension, Cardiovascular disease in UK Biobank. Table S2. Component definitions used in the UK Biobank study of the healthy lifestyle score. Table S3. Diet component definitions used in the UK Biobank study. Table S4. Healthy sleep pattern definitions used in the UK Biobank study. Figure S1. Flowchart for the Selection of the Analyzed Study Sample From the UK Biobank Study. Table S5. Hazard Ratios Adjusted with Different Models for T2DM Events According to Healthy Lifestyle Score. Table S6. Hazard Ratios for T2DM Events stratified by individual healthy lifestyle factors. Table S7. Multivariable adjusted hazard ratios for T2DM events according to healthy sleep score. Table S8. Hazard ratios for T2DM according to healthy lifestyle score among participants with dysglycaemia and hypertension. Table S9. Hazard ratios for T2DM excluding the first 2 years incidence cases according to healthy lifestyle score. Table S10. Hazard ratios for T2DM excluding BMI< 18.5kg/m2 incidence cases according to healthy lifestyle score. Table S11. Hazard ratios for T2DM excluding sleep apnea individuals at baseline. Table S12. Multivariable-adjusted PARs% (95% CIs) for incident T2DM by the specific combination of low-risk lifestyle factors among 430,971 participants.

Published
2021
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91. Predictive models for adverse clinical outcomes in Chinese patients with atrial fibrillation undergoing percutaneous coronary intervention with stenting

Author

Zheng, Jian-Yong, primary, Cao, Yi, additional, Li, Dong-Tao, additional, Qiu, Yi-Gang, additional, Zhao, Li, additional, Xu, Zheng-Ming, additional, Huang, Yi-Xiong, additional, Hong, Zhi-Bo, additional, Li, Tian-Chang, additional, Tang, Yi-Da, additional, Guo, Cheng-Jun, additional, Ma, Zhi-Min, additional, Wu, Yong-Quan, additional, and Chen, Yu, additional

Published
2021
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92. Tumor Necrosis Factor α–Induced Protein 8–Like 2 Alleviates Nonalcoholic Fatty Liver Disease Through Suppressing Transforming Growth Factor Beta–Activated Kinase 1 Activation

Author

Liu, Yupeng, primary, Song, Jingjing, additional, Yang, Juan, additional, Zheng, Jilin, additional, Yang, Ling, additional, Gao, Jun, additional, Tian, Song, additional, Liu, Zhen, additional, Meng, Xiangbin, additional, Wang, Jian‐Cheng, additional, Dai, Zhifei, additional, and Tang, Yi‐Da, additional

Published
2021
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95. The Association Between High-Sensitivity C-Reactive Protein/Albumin Ratio and Cardiovascular Prognosis in Patients Undergoing Percutaneous Coronary Intervention.

Author

Yang, Jie, Li, Chen, Zheng, Yitian, Gao, Jun, Liu, Yu Peng, Wang, Jing jia, Song, Jing jing, Zhou, Qing, Meng, Xiangbin, Zhang, Kuo, Wang, Wenyao, Shao, Chunli, and Tang, Yi-Da

Subjects
C-reactive protein, PERCUTANEOUS coronary intervention, CARDIOVASCULAR diseases, BIRTHING centers, ADULT respiratory distress syndrome
Abstract

Limited studies have focused on the impact of high-sensitivity C-reactive protein (hsCRP) to albumin ratio (CAR) on cardiovascular outcomes in patients undergoing percutaneous coronary intervention (PCI). Hence, the present study evaluates the association between CAR and cardiovascular outcomes in patients undergoing drug-eluting stent (DES) implantation. We consecutively enrolled 9375 CHD patients undergoing DES implantation. All patients were divided into 3 groups according to their CAR: tertile 1 (CAR ≤.02, n=3125), tertile 2 (.02.06, n = 3125). The primary endpoint was major adverse cardiovascular and cerebrovascular events (MACCE). Kaplan-Meier analysis indicated that the incidences of MACCE and MI increased with high tertiles of the CAR (MACCE: 8.7 vs 10.5 vs 12.3%, log-rank P <.001; MI: 3.3 vs 4.0 vs 4.7%, long-rank P =.015). Cox regression analysis suggested that CAR was an independent risk factors for MACCE (HR per standard deviation (SD) increase: 1.07, 95% CI, 1.01–1.14, P =.024), and MI (HR per SD increase: 1.11, 95% CI, 1.01–1.22, P =.028). In conclusion, the CAR is an independent predictor of MACCE and MI in CHD patients. [ABSTRACT FROM AUTHOR]

Published
2022
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96. Corrigendum: The Prevalence of Familial Hypercholesterolemia (FH) in Chinese Patients With Acute Myocardial Infarction (AMI): Data From Chinese Acute Myocardial Infarction (CAMI) Registry

Author

Shi, Hui-Wei, Yang, Jin-Gang, Wang, Yang, Li, Wei, Guo, Yuan-Lin, Gao, Ying, Tang, Yi-Da, Li, Jian-Jun, Wu, Na-Qiong, and Yang, Yue-Jin

Subjects
heterozygous familial hypercholesterolemia, lcsh:Diseases of the circulatory (Cardiovascular) system, Chinese, clinical manifestations, lcsh:RC666-701, prevalence, Correction, acute myocardial infarction, Cardiovascular Medicine, Cardiology and Cardiovascular Medicine
Published
2020
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100. Treatment of subclinical hypothyroidism reverses ischemia and prevents myocyte loss and progressive LV dysfunction in hamsters with dilated cardiomyopathy

Author

Khalife, Wissam I., Tang, Yi-Da, Kuzman, James A., Thomas, Tracy A., Anderson, Brent E., Said, Suleman, Tille, Patricia, Schlenker, Evelyn H., and Gerdes, A. Martin

Subjects
Hypothyroidism -- Risk factors, Heart diseases -- Development and progression, Thyroid hormones -- Health aspects, Hamsters -- Health aspects, Cardiomyopathy, Dilated, Biological sciences
Abstract

Growing evidence suggests that thyroid dysfunction may contribute to progression of cardiac disease to heart failure. We investigated the effects of a therapeutic dose of thyroid hormones (TH) on cardiomyopathic (CM) hamsters from 4 to 6 mo of age. CM hamsters had subclinical hypothyroidism (normal thyroxine, elevated TSH). Left ventricular (LV) function was determined by echocardiography and hemodynamics. Whole tissue pathology and isolated myocyte size and number were assessed. TH treatment prevented the decline in heart rate and rate of LV pressure increase and improved LV ejection fraction. The percentage of fibrosis/necrosis in untreated 4-mo-old CM (4CM; 15.5 [+ or -] 2.2%) and 6-mo-old CM (6CM; 21.5 [+ or -] 2.4%) hamsters was pronounced and was reversed in treated CM (TCM; 11.9 [+ or -] 0.9%) hamsters. Total ventricular myocyte number was the same between 4- and 6-mo-old controls but was reduced by 30% in 4CM and 43% in 6CM hamsters. TH treatment completely prevented further loss of myocytes in TCM hamsters. Compared with agematched controls, resting and maximum coronary blood flow was impaired in 4CM and 6CM hamsters. Blood flow was completely normalized by TH treatment. We conclude that TH treatment of CM hamsters with subclinical hypothyroidism normalized impaired coronary blood flow, which prevented the decline in LV function and loss of myocytes. thyroid hormones; remodeling; fibrosis; blood flow

Published
2005

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