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51. Trends in Laboratory-Confirmed SARS-CoV-2 Reinfections and Associated Hospitalizations and Deaths Among Adults Aged ≥18 Years — 18 U.S. Jurisdictions, September 2021–December 2022

Author

Ma, Kevin C., primary, Dorabawila, Vajeera, additional, León, Tomás M., additional, Henry, Hannah, additional, Johnson, Amelia G., additional, Rosenberg, Eli, additional, Mansfield, Joshua A., additional, Midgley, Claire M., additional, Plumb, Ian D., additional, Aiken, Julia, additional, Khanani, Quratul Ain, additional, Auche, Steven, additional, Bayoumi, Nagla S., additional, Bennett, Sarah A., additional, Bernu, Carmen, additional, Chang, Carolyn, additional, Como-Sabetti, Kathryn J., additional, Cueto, Kevin, additional, Cunningham, Spencer, additional, Eddy, Meredith, additional, Falender, Rebecca A., additional, Fleischauer, Aaron, additional, Frank, Darren M., additional, Harrington, Pauline, additional, Hoskins, Mikhail, additional, Howsare, Adam, additional, Ingaiza, Lucy M., additional, Islam, Aras S., additional, Jensen, Shelli A., additional, Jones, Jefferson M., additional, Kambach, Grace, additional, Kanishka, FNU, additional, Levin, Yuriy, additional, Masarik, John F., additional, Meyer, Stephanie D., additional, Milroy, Lauren, additional, Morris, Keeley J., additional, Olmstead, John, additional, Olsen, Nina S., additional, Omoike, Enaholo, additional, Patel, Komal, additional, Pettinger, Amanda, additional, Pike, Melissa A., additional, Reed, Isaiah G., additional, Slocum, Elizabeth, additional, Sutton, Melissa, additional, Tilakaratne, Buddhi P., additional, Vest, Hailey, additional, Vostok, Johanna, additional, Wang, Jennifer S., additional, Watson-Lewis, Lydia, additional, Wienkes, Haley N., additional, Hagen, Melissa Briggs, additional, Silk, Benjamin J., additional, and Scobie, Heather M., additional

Published
2023
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52. COVID-19-Associated Hospitalizations Among U.S. Infants Aged <6 Months--COVID-NET, 13 States, June 2021-August 2022

Author

Hamid, Sarah, Woodworth, Kate, Pham, Huong, Milucky, Jennifer, Chai, Shua J., Kawasaki, Breanna, Yousey-Hindes, Kimberly, Anderson, Evan J., Henderson, Justin, Lynfield, Ruth, Pacheco, Francesca, Barney, Grant, Bennett, Nancy M., Shiltz, Eli, Sutton, Melissa, Talbot, H. Keipp, Price, Andrea, Havers, Fiona P., and Taylor, Christopher A.

Subjects
United States. Department of Health and Human Services, Vaccination, Medical colleges, Health
Abstract

COVID-19--associated hospitalization rates are highest among adults aged [greater than or equal to] 65 years (1); however, COVID-19 can and does cause severe and fatal outcomes in children, including infants [...]

Published
2022

53. Characteristics and Outcomes Among Adults Aged ≥60 Years Hospitalized with Laboratory-Confirmed Respiratory Syncytial Virus — RSV-NET, 12 States, July 2022–June 2023

Author

Kirley, Pam Daily, Austin, Elizabeth, Kim, Daewi, Surell, Chandler, Monroe, Maya, Leegwater, Lauren, Mumm, Erica, Bleecker, Molly, Rowe, Adam, Popham, Kevin, Novak, Arilene, Schaffner, William, Havers, Fiona P., Whitaker, Michael, Melgar, Michael, Chatwani, Bhoomija, Chai, Shua J., Alden, Nisha B., Meek, James, Openo, Kyle P., Ryan, Patricia A., Kim, Sue, Lynfield, Ruth, Shaw, Yomei P., Barney, Grant, Tesini, Brenda L., Sutton, Melissa, Talbot, H. Keipp, Olsen, Kristen P., and Patton, Monica E.

Published
2023
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54. Laboratory-Confirmed COVID-19--Associated Hospitalizations Among Adults During SARS-CoV-2 Omicron BA.2 Variant Predominance--COVID-19--Associated Hospitalization Surveillance Network, 14 States, June 20, 2021-May 31, 2022

Author

Havers, Fiona P., Patel, Kadam, Whitaker, Michael, Milucky, Jennifer, Reingold, Arthur, Armistead, Isaac, Meek, James, Anderson, Evan J., Weigel, Andy, Reeg, Libby, Seys, Scott, Ropp, Susan L., Spina, Nancy, Felsen, Christina B., Moran, Nancy E., Sutton, Melissa, Talbot, H. Keipp, George, Andrea, and Taylor, Christopher A.

Subjects
Adults, Health
Abstract

Beginning the week of March 20-26, 2022, the Omicron BA.2 variant of SARS-CoV-2, the virus that causes COVID-19, became the predominant circulating variant in the United States, accounting for >50% [...]

Published
2022

55. Factors Associated with Severe Outcomes Among Immunocompromised Adults Hospitalized for COVID-19--COVID-NET, 10 States, March 2020-February 2022

Author

Singson, Jason Robert C., Kirley, Pam Daily, Pham, Huong, Rothrock, Gretchen, Armistead, Isaac, Meek, James, Anderson, Evan J., Reeg, Libby, Lynfield, Ruth, Ropp, Susan, Muse, Alison, Felsen, Christina B., Sutton, Melissa, Talbot, H. Keipp, Havers, Fiona P., Taylor, Christopher A., Reingold, Arthur, and Chai, Shua J.

Subjects
Vaccination, Adults, Hospital patients, Health
Abstract

Immunocompromised persons are at increased risk for severe COVID-19--related outcomes, including intensive care unit (ICU) admission and death (1). Data on adults aged >18 years hospitalized with laboratory-confirmed COVID-19 from [...]

Published
2022

56. Hospitalizations of Children Aged 5-11 Years with Laboratory-Confirmed COVID-19--COVID-NET, 14 States, March 2020-February 2022

Author

Shi, Dallas S., Whitaker, Michael, Marks, Kristin J., Anglin, Onika, Milucky, Jennifer, Patel, Kadam, Pham, Huong, Chai, Shua J., Kawasaki, Breanna, Meek, James, Anderson, Evan J., Weigel, Andy, Henderson, Justin, Lynfield, Ruth, Ropp, Susan L., Muse, Alison, Bushey, Sophrena, Billing, Laurie M., Sutton, Melissa, Talbot, H. Keipp, Price, Andrea, Taylor, Christopher A., and Havers, Fiona P.

Subjects
Pfizer Inc., Vaccines, Health
Abstract

On April 19, 2022, this report was posted as an MMWR Early Release on the MMWR website (https://www.cdc.gov/mmwr). On October 29, 2021, the Food and Drug Administration expanded the Emergency [...]

Published
2022

57. COVID-19-Associated Hospitalizations Among Adults During SARS-CoV-2 Delta and Omicron Variant Predominance, by Race/Ethnicity and Vaccination Status--COVID-NET, 14 States, July 2021-January 2022

Author

Taylor, Christopher A., Whitaker, Michael, Anglin, Onika, Milucky, Jennifer, Patel, Kadam, Pham, Huong, Chai, Shua J., Alden, Nisha B., Yousey-Hindes, Kimberly, Anderson, Evan J., Teno, Kenzie, Reeg, Libby, Como-Sabetti, Kathryn, Bleecker, Molly, Barney, Grant, Bennett, Nancy M., Billing, Laurie M., Sutton, Melissa, Talbot, H. Keipp, McCaffrey, Keegan, and Havers, Fiona P.

Subjects
Vaccination, Adults, Health
Abstract

On March 18, 2022, this report was posted as an MMWR Early Release on the MMWR website (https://www.cdc.gov/mmwr). Beginning the week of December 19-25, 2021, the B.1.1.529 (Omicron) variant of [...]

Published
2022

58. Hospitalization of Infants and Children Aged 0-4 Years with Laboratory- Confirmed COVID-19--COVID-NET, 14 States, March 2020-February 2022

Author

Marks, Kristin J., Whitaker, Michael, Agathis, Nickolas T., Anglin, Onika, Milucky, Jennifer, Patel, Kadam, Pham, Huong, Kirley, Pam Daily, Kawasaki, Breanna, Meek, James, Anderson, Evan J., Weigel, Andy, Kim, Sue, Lynfield, Ruth, Ropp, Susan L., Spina, Nancy L., Bennett, Nancy M., Shiltz, Eli, Sutton, Melissa, Talbot, H. Keipp, Price, Andrea, Taylor, Christopher A., and Havers, Fiona P.

Subjects
United States. Department of Health and Human Services, Vaccination, Health
Abstract

On March 15, 2022, this report was posted as an MMWR Early Release on the MMWR website (https://www.cdc.gov/mmwr). The B.1.1.529 (Omicron) variant ofSARS-CoV-2, the virus that causes COVID-19, has been [...]

Published
2022

59. COVID-19--Associated Hospitalizations Among U.S. Adults Aged ≥65 Years -- COVID-NET, 13 States, January--August 2023.

Author

Taylor, Christopher A., Patel, Kadam, Patton, Monica E., Reingold, Arthur, Kawasaki, Breanna, Meek, James, Openo, Kyle, Ryan, Patricia A., Falkowski, Anna, Bye, Erica, Plymesser, Kelly, Spina, Nancy, Tesini, Brenda L., Moran, Nancy E., Sutton, Melissa, Talbot, H. Keipp, George, Andrea, and Havers, Fiona P.

Subjects
HOSPITAL care, CORONAVIRUS diseases, HEALTH of older people, INFECTION, VACCINATION, MEDICAL research
Abstract

Adults aged ≥65 years remain at elevated risk for severe COVID-19 disease and have higher COVID-19--associated hospitalization rates compared with those in younger age groups. Data from the COVID-19--Associated Hospitalization Surveillance Network (COVID-NET) were analyzed to estimate COVID-19--associated hospitalization rates during January-- August 2023 and identify demographic and clinical characteristics of hospitalized patients aged ≥65 years during January--June 2023. Among adults aged ≥65 years, hospitalization rates more than doubled, from 6.8 per 100,000 during the week ending July 15 to 16.4 per 100,000 during the week ending August 26, 2023. Across all age groups, adults aged ≥65 years accounted for 62.9% (95% CI = 60.1%--65.7%) of COVID-19--associated hospitalizations, 61.3% (95% CI = 54.7%--67.6%) of intensive care unit admissions, and 87.9% (95% CI = 80.5%--93.2%) of in-hospital deaths associated with COVID-19 hospitalizations. Most hospitalized adults aged ≥65 years (90.3%; 95% CI = 87.2%--92.8%) had multiple underlying conditions, and fewer than one quarter (23.5%; 95% CI = 19.5%--27.7%) had received the recommended COVID-19 bivalent vaccine. Because adults aged ≥65 years remain at increased risk for COVID-19--associated hospitalization and severe outcomes, guidance for this age group should continue to focus on measures to prevent SARS-CoV-2 infection, encourage vaccination, and promote early treatment for persons who receive a positive SARS-CoV-2 test result to reduce their risk for severe COVID-19--associated outcomes. [ABSTRACT FROM AUTHOR]

Published
2023
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60. Characteristics and Outcomes Among Adults Aged ≥60 Years Hospitalized with Laboratory-Confirmed Respiratory Syncytial Virus -- RSV-NET, 12 States, July 2022--June 2023.

Author

Havers, Fiona P., Whitaker, Michael, Melgar, Michael, Chatwani, Bhoomija, Chai, Shua J., Alden, Nisha B., Meek, James, Openo, Kyle P., Ryan, Patricia A., Kim, Sue, Lynfield, Ruth, Shaw, Yomei P., Barney, Grant, Tesini, Brenda L., Sutton, Melissa, Talbot, H. Keipp, and Patton, Kristen P.

Subjects
VACCINATION, RESPIRATORY syncytial virus infections, HOSPITAL care, HEALTH of older people, RESPIRATORY syncytial virus, MEDICAL research
Abstract

Respiratory syncytial virus (RSV) causes substantial morbidity and mortality in older adults. In May 2023, two RSV vaccines were approved for prevention of RSV lower respiratory tract disease in adults aged ≥60 years. In June 2023, CDC recommended RSV vaccination for adults aged ≥60 years, using shared clinical decision-making. Using data from the Respiratory Syncytial Virus--Associated Hospitalization Surveillance Network, a population-based hospitalization surveillance system operating in 12 states, this analysis examined characteristics (including age, underlying medical conditions, and clinical outcomes) of 3,218 adults aged ≥60 years who were hospitalized with laboratory-confirmed RSV infection during July 2022--June 2023. Among a random sample of 1,634 older adult patients with RSV-associated hospitalization, 54.1% were aged ≥75 years, and the most common underlying medical conditions were obesity, chronic obstructive pulmonary disease, congestive heart failure, and diabetes. Severe outcomes occurred in 18.5% (95% CI = 15.9%--21.2%) of hospitalized patients aged ≥60 years. Overall, 17.0% (95% CI = 14.5%--19.7%) of patients with RSV infection were admitted to an intensive care unit, 4.8% (95% CI = 3.5%--6.3%) required mechanical ventilation, and 4.7% (95% CI = 3.6%--6.1%) died; 17.2% (95% CI = 14.9%--19.8%) of all cases occurred in long-term care facility residents. These data highlight the importance of prioritizing those at highest risk for severe RSV disease and suggest that clinicians and patients consider age (particularly age ≥75 years), long-term care facility residence, and underlying medical conditions, including chronic obstructive pulmonary disease and congestive heart failure, in shared clinical decisionmaking when offering RSV vaccine to adults aged ≥60 years. [ABSTRACT FROM AUTHOR]

Published
2023
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61. Vaccination Status and Trends in Adult Coronavirus Disease 2019–Associated Hospitalizations by Race and Ethnicity: March 2020–August 2022.

Author

Ko, Jean Y, Pham, Huong, Anglin, Onika, Chai, Shua J, Alden, Nisha B, Meek, James, Anderson, Evan J, Weigel, Andy, Kohrman, Alexander, Lynfield, Ruth, Rudin, Dominic, Barney, Grant, Bennett, Nancy M, Billing, Laurie M, Sutton, Melissa, Talbot, H Keipp, Swain, Ashley, Havers, Fiona P, Taylor, Christopher A, and Team, COVID-NET Surveillance

Subjects
EVALUATION of medical care, RACISM, RELATIVE medical risk, IMMUNIZATION, COVID-19, CONFIDENCE intervals, RACE, HOSPITAL care, VACCINATION status, HEALTH equity, STATISTICAL sampling, ODDS ratio
Abstract

Background We sought to determine whether race/ethnicity disparities in severe coronavirus disease 2019 (COVID-19) outcomes persist in the era of vaccination. Methods Population-based age-adjusted monthly rate ratios (RRs) of laboratory-confirmed COVID-19–associated hospitalizations were calculated among adult patients from the COVID-19–Associated Hospitalization Surveillance Network, March 2020 - August 2022 by race/ethnicity. Among randomly sampled patients July 2021 - August 2022, RRs for hospitalization, intensive care unit (ICU) admission, and in-hospital mortality were calculated for Hispanic, Black, American Indian/Alaskan Native (AI/AN), and Asian/Pacific Islander (API) persons vs White persons. Results Based on data from 353 807 patients, hospitalization rates were higher among Hispanic, Black, and AI/AN vs White persons March 2020 - August 2022, yet the magnitude declined over time (for Hispanic persons, RR = 6.7; 95% confidence interval [CI], 6.5–7.1 in June 2020 vs RR < 2.0 after July 2021; for AI/AN persons, RR = 8.4; 95% CI, 8.2–8.7 in May 2020 vs RR < 2.0 after March 2022; and for Black persons RR = 5.3; 95% CI, 4.6–4.9 in July 2020 vs RR < 2.0 after February 2022; all P ≤.001). Among 8706 sampled patients July 2021 - August 2022, hospitalization and ICU admission RRs were higher for Hispanic, Black, and AI/AN patients (range for both, 1.4–2.4) and lower for API (range for both, 0.6–0.9) vs White patients. All other race and ethnicity groups had higher in-hospital mortality rates vs White persons (RR range, 1.4–2.9). Conclusions Race/ethnicity disparities in COVID-19–associated hospitalizations declined but persist in the era of vaccination. Developing strategies to ensure equitable access to vaccination and treatment remains important. [ABSTRACT FROM AUTHOR]

Published
2023
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62. Influenza Antiviral Use in Patients Hospitalized With Laboratory-Confirmed Influenza in the United States, FluSurv-NET, 2015–2019

Author

Tenforde, Mark W, primary, Cummings, Charisse N, additional, O’Halloran, Alissa C, additional, Rothrock, Gretchen, additional, Kirley, Pam Daily, additional, Alden, Nisha B, additional, Meek, James, additional, Yousey-Hindes, Kimberly, additional, Openo, Kyle P, additional, Anderson, Evan J, additional, Monroe, Maya L, additional, Kim, Sue, additional, Nunez, Val Tellez, additional, McMahon, Melissa, additional, McMullen, Chelsea, additional, Khanlian, Sarah A, additional, Spina, Nancy L, additional, Muse, Alison, additional, Gaitán, Maria A, additional, Felsen, Christina B, additional, Lung, Krista, additional, Shiltz, Eli, additional, Sutton, Melissa, additional, Thomas, Ann, additional, Talbot, H Keipp, additional, Schaffner, William, additional, Price, Andrea, additional, Chatelain, Ryan, additional, Reed, Carrie, additional, and Garg, Shikha, additional

Published
2022
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63. Case report: Persistent shedding of a live vaccine-derived rubella virus in a young man with severe combined immunodeficiency and cutaneous granuloma

Author

Bonner, Kimberly E., primary, Sukerman, Ellie, additional, Liko, Juventila, additional, Lanzieri, Tatiana M., additional, Sutton, Melissa, additional, DeBess, Emilio, additional, Leesman, Christopher, additional, Icenogle, Joseph, additional, Hao, LiJuan, additional, Chen, Min-hsin, additional, Faisthalab, Raeesa, additional, Leman, Richard F., additional, Cieslak, Paul R., additional, DeRavin, Suk See, additional, and Perelygina, Ludmila, additional

Published
2022
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64. 303. Viral and bacterial infections among adults hospitalized with COVID-19, Coronavirus Disease 2019-Associated Hospitalization Surveillance Network, 14 states, March 2020–February 2022

Author

Melisa, Shah, primary, Taylor, Christopher, additional, Patel, Kadam, additional, Milucky, Jennifer, additional, Whitaker, Michael, additional, Pham, Huong, additional, Anglin, Onika, additional, Reingold, Arthur, additional, Armistead, Isaac, additional, Yousey-Hindes, Kimberly, additional, Anderson, Evan J, additional, Weigel, Andy, additional, Reeg, Libby, additional, Mumm, Erica, additional, Ropp, Susan L, additional, Muse, Alison G, additional, Bushey, Sophrena, additional, Shiltz, Eli, additional, Sutton, Melissa, additional, Talbot, Keipp, additional, Price, Andrea, additional, and Havers, Fiona P, additional

Published
2022
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65. 1537. Influenza-Associated Hospitalization Rates and Proportion of Hospitalizations with Influenza and SARS-CoV-2 Coinfection, FluSurv-NET, October 1, 2021–April 23, 2022

Author

Garg, Shikha, primary, Cummings, Charisse N, additional, Ujamaa, Dawud, additional, Kirley, Pam Daily, additional, Alden, Nisha B, additional, Correa, Maria, additional, Anderson, Evan J, additional, Weigel, Andy, additional, Monroe, Maya, additional, Nunez, Val Tellez, additional, McMahon, Melissa, additional, Ropp, Susan L, additional, Spina, Nancy L, additional, Gaitan, Maria, additional, Shiltz, Eli, additional, Sutton, Melissa, additional, Talbot, Keipp, additional, Crossland, Melanie, additional, and Reed, Carrie, additional

Published
2022
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66. 1877. COVID-19-Associated Hospitalizations among Long-Term Care Facility Residents Ages ≥65 Years — COVID-NET, 14 U.S. States, March 2020–January 2022

Author

Taylor, Christopher, primary, Whitaker, Michael, additional, Anglin, Onika, additional, Pham, Huong, additional, Patel, Kadam, additional, Milucky, Jennifer, additional, Reingold, Arthur, additional, Alden, Nisha B, additional, Meek, James, additional, Ward, Katelyn, additional, Teno, Kenzie, additional, Kohrman, Alexander, additional, Como-Sabetti, Kathy, additional, Eisenberg, Nancy, additional, Spina, Nancy L, additional, Bushey, Sophrena, additional, Billing, Laurie M, additional, Sutton, Melissa, additional, Talbot, Keipp, additional, Swain, Ashley, additional, and Havers, Fiona P, additional

Published
2022
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67. 2209. RSV-associated Hospitalizations in Adults Aged ≥18 Years and the Impact of the COVID-19 Pandemic in the United States, October 2018 – February 2022

Author

Havers, Fiona P, primary, Whitaker, Michael, additional, Pham, Huong, additional, Anglin, Onika, additional, Milucky, Jennifer, additional, Patel, Kadam, additional, Kirley, Pam Daily, additional, Austin, Elizabeth, additional, Meek, James, additional, Anderson, Evan J, additional, Monroe, Maya, additional, Brown, Chloe, additional, Bye, Erica, additional, Pacheco, Francesca, additional, Barney, Grant, additional, Cafferky, Virginia, additional, Sutton, Melissa, additional, Talbot, Keipp, additional, Chatelain, Ryan, additional, Gerber, Susan I, additional, Langley, Gayle, additional, Kim, Lindsay, additional, and Taylor, Christopher, additional

Published
2022
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68. Hospitalizations of Children and Adolescents with Laboratory-Confirmed COVID-19--COVID-NET, 14 States, July 2021-January 2022

Author

Marks, Kristin J., Whitaker, Michael, Anglin, Onika, Milucky, Jennifer, Patel, Kadam, Pham, Huong, Chai, Shua J., Kirley, Pam Daily, Armistead, Isaac, McLafferty, Sarah, Meek, James, Yousey-Hindes, Kimberly, Anderson, Evan J., Openo, Kyle P., Weigel, Andy, Henderson, Justin, Nunez, Val Tellez, Como-Sabetti, Kathryn, Lynfield, Ruth, Ropp, Susan L., Smelser, Chad, Barney, Grant R., Muse, Alison, Bennett, Nancy M., Bushey, Sophrena, Billing, Laurie M., Shiltz, Eli, Abdullah, Nasreen, Sutton, Melissa, Schaffner, William, Talbot, H. Keipp, Chatelain, Ryan, George, Andrea, Taylor, Christopher A., McMorrow, Meredith L., Perrine, Cria G., and Havers, Fiona P.

Subjects
Health
Abstract

On February 15, 2022, this report was posted as an MMWR Early Release on the MMWR website (https://www.cdc.gov/mmwr). The first U.S. case of COVID-19 attributed to the Omicron variant of [...]

Published
2022

70. COVID-19-Associated Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, January 2021 to April 2022

Author

Havers, Fiona P., primary, Pham, Huong, additional, Taylor, Christopher A., additional, Whitaker, Michael, additional, Patel, Kadam, additional, Anglin, Onika, additional, Kambhampati, Anita K., additional, Milucky, Jennifer, additional, Zell, Elizabeth, additional, Moline, Heidi L., additional, Chai, Shua J., additional, Kirley, Pam Daily, additional, Alden, Nisha B., additional, Armistead, Isaac, additional, Yousey-Hindes, Kimberly, additional, Meek, James, additional, Openo, Kyle P., additional, Anderson, Evan J., additional, Reeg, Libby, additional, Kohrman, Alexander, additional, Lynfield, Ruth, additional, Como-Sabetti, Kathryn, additional, Davis, Elizabeth M., additional, Cline, Cory, additional, Muse, Alison, additional, Barney, Grant, additional, Bushey, Sophrena, additional, Felsen, Christina B., additional, Billing, Laurie M., additional, Shiltz, Eli, additional, Sutton, Melissa, additional, Abdullah, Nasreen, additional, Talbot, H. Keipp, additional, Schaffner, William, additional, Hill, Mary, additional, George, Andrea, additional, Hall, Aron J., additional, Bialek, Stephanie R., additional, Murthy, Neil C., additional, Murthy, Bhavini Patel, additional, and McMorrow, Meredith, additional

Published
2022
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71. Severity of Disease Among Adults Hospitalized with Laboratory-Confirmed COVlD-19 Before and During the Period of SARS-CoV-2 B.1.617.2 (Delta) Predominance--COVID-NET, 14 States, January-August 2021

Author

Taylor, Christopher A., Patel, Kadam, Pham, Huong, Whitaker, Michael, Anglin, Onika, Kambhampati, Anita K., Milucky, Jennifer, Chai, Shua J., Kirley, Pam Daily, Alden, Nisha B., Armistead, Isaac, Meek, James, Yousey-Hindes, Kimberly, Anderson, Evan J., Openo, Kyle P., Teno, Kenzie, Weigel, Andy, Monroe, Maya L., Ryan, Patricia A., Henderson, Justin, Nunez, Val Tellez, Bye, Erica, Lynfield, Ruth, Poblete, Mayvilynne, Smelser, Chad, Barney, Grant R., Spina, Nancy L., Bennett, Nancy M., Popham, Kevin, Billing, Laurie M., Shiltz, Eli, Abdullah, Nasreen, Sutton, Melissa, Schaffner, William, Talbot, H. Keipp, Ortega, Jake, Price, Andrea, Garg, Shikha, and Havers, Fiona P.

Subjects
Infection, Adults, Health
Abstract

On October 22, 2021, this report was posted as an MMWR Early Release on the MMWR website (https:llwww.cdc.gov/mmwr). In mid-June 2021, B.1.671.2 (Delta) became the predominant variant of SARS-CoV-2, the [...]

Published
2021

72. Pediatric SARS-CoV-2 Seroprevalence, Oregon, USA, November 1, 2020-June 30, 2022.

Author

Falender, Rebecca A., Mitchell, Paul G., Guzman-Cottrill, Judith A., Cieslak, Paul R., and Sutton, Melissa

Subjects
SEROPREVALENCE, SARS-CoV-2
Abstract

We estimated SARS-CoV-2 seroprevalence in children in Oregon, USA, at 6 time points. Seroprevalence increased linearly during November 2020-December 2021 and peaked in February 2022 at 38.8% (95% CI 32.8%-46.5%). We observed no increase in the seroprevalence trend after widespread school reopening. Seroprevalence estimates complement case-based cumulative incidence. [ABSTRACT FROM AUTHOR]

Published
2023
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74. Effectiveness of COVID-19 Vaccines in Preventing Hospitalization Among Adults Aged [greater than or equal to] 65 Years--COVID-NET, 13 States, February-April 2021

Author

Moline, Heidi L., Whitaker, Michael, Deng, Li, Rhodes, Julia C., Milucky, Jennifer, Pham, Huong, Patel, Kadam, Anglin, Onika, Reingold, Arthur, Chai, Shua J., Alden, Nisha B., Kawasaki, Breanna, Meek, James, Yousey-Hindes, Kimberly, Anderson, Evan J., Farley, Monica M., Ryan, Patricia A., Kim, Sue, Nunez, Val Tellez, Como-Sabetti, Kathryn, Lynfield, Ruth, Sosin, Daniel M., McMullen, Chelsea, Muse, Alison, Barney, Grant, Bennett, Nancy M., Bushey, Sophrena, Shiltz, Jessica, Sutton, Melissa, Abdullah, Nasreen, Talbot, H. Keipp, Schaffner, William, Chatelain, Ryan, Ortega, Jake, Murthy, Bhavini Patel, Zell, Elizabeth, Schrag, Stephanie J., Taylor, Christopher, Shang, Nong, Verani, Jennifer R., and Havers, Fiona P.

Subjects
Johnson & Johnson, Pfizer Inc., Adults, Vaccines, Pharmaceutical industry, Health
Abstract

On August 6, 2021, this report was posted as an MMWR Early Release on the MMWR website (https://www.cdc.gov/mmwr). Clinical trials of COVID-19 vaccines currently authorized for emergency use in the [...]

Published
2021

77. Bacterial and viral infections among adults hospitalized with COVID‐19, COVID‐NET, 14 states, March 2020–April 2022.

Author

Shah, Melisa M., Patel, Kadam, Milucky, Jennifer, Taylor, Christopher A., Reingold, Arthur, Armistead, Isaac, Meek, James, Anderson, Evan J., Weigel, Andy, Reeg, Libby, Como‐Sabetti, Kathryn, Ropp, Susan L., Muse, Alison, Bushey, Sophrena, Shiltz, Eli, Sutton, Melissa, Talbot, H. Keipp, Chatelain, Ryan, and Havers, Fiona P.

Subjects
BACTERIAL diseases, VIRUS diseases, COVID-19, RESPIRATORY syncytial virus, PARAINFLUENZA viruses, ADULTS, PLANT viruses
Abstract

Background: Bacterial and viral infections can occur with SARS‐CoV‐2 infection, but prevalence, risk factors, and associated clinical outcomes are not fully understood. Methods: We used the Coronavirus Disease 2019‐Associated Hospitalization Surveillance Network (COVID‐NET), a population‐based surveillance system, to investigate the occurrence of bacterial and viral infections among hospitalized adults with laboratory‐confirmed SARS‐CoV‐2 infection between March 2020 and April 2022. Clinician‐driven testing for bacterial pathogens from sputum, deep respiratory, and sterile sites were included. The demographic and clinical features of those with and without bacterial infections were compared. We also describe the prevalence of viral pathogens including respiratory syncytial virus, rhinovirus/enterovirus, influenza, adenovirus, human metapneumovirus, parainfluenza viruses, and non‐SARS‐CoV‐2 endemic coronaviruses. Results: Among 36 490 hospitalized adults with COVID‐19, 53.3% had bacterial cultures taken within 7 days of admission and 6.0% of these had a clinically relevant bacterial pathogen. After adjustment for demographic factors and co‐morbidities, bacterial infections in patients with COVID‐19 within 7 days of admission were associated with an adjusted relative risk of death 2.3 times that of patients with negative bacterial testing. Staphylococcus aureus and Gram‐negative rods were the most frequently isolated bacterial pathogens. Among hospitalized adults with COVID‐19, 2766 (7.6%) were tested for seven virus groups. A non‐SARS‐CoV‐2 virus was identified in 0.9% of tested patients. Conclusions: Among patients with clinician‐driven testing, 6.0% of adults hospitalized with COVID‐19 were identified to have bacterial coinfections and 0.9% were identified to have viral coinfections; identification of a bacterial coinfection within 7 days of admission was associated with increased mortality. [ABSTRACT FROM AUTHOR]

Published
2023
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78. Comparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021)

Author

Delahoy, Miranda J, primary, Ujamaa, Dawud, additional, Taylor, Christopher A, additional, Cummings, Charisse, additional, Anglin, Onika, additional, Holstein, Rachel, additional, Milucky, Jennifer, additional, O’Halloran, Alissa, additional, Patel, Kadam, additional, Pham, Huong, additional, Whitaker, Michael, additional, Reingold, Arthur, additional, Chai, Shua J, additional, Alden, Nisha B, additional, Kawasaki, Breanna, additional, Meek, James, additional, Yousey-Hindes, Kimberly, additional, Anderson, Evan J, additional, Openo, Kyle P, additional, Weigel, Andy, additional, Teno, Kenzie, additional, Reeg, Libby, additional, Leegwater, Lauren, additional, Lynfield, Ruth, additional, McMahon, Melissa, additional, Ropp, Susan, additional, Rudin, Dominic, additional, Muse, Alison, additional, Spina, Nancy, additional, Bennett, Nancy M, additional, Popham, Kevin, additional, Billing, Laurie M, additional, Shiltz, Eli, additional, Sutton, Melissa, additional, Thomas, Ann, additional, Schaffner, William, additional, Talbot, H Keipp, additional, Crossland, Melanie T, additional, McCaffrey, Keegan, additional, Hall, Aron J, additional, Burns, Erin, additional, McMorrow, Meredith, additional, Reed, Carrie, additional, Havers, Fiona P, additional, and Garg, Shikha, additional

Published
2022
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79. Comparison of influenza and COVID-19–associated hospitalizations among children < 18 years old in the United States — FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021)

Author

Delahoy, Miranda J., primary, Ujamaa, Dawud, additional, Taylor, Christopher A., additional, Cummings, Charisse, additional, Anglin, Onika, additional, Holstein, Rachel, additional, Milucky, Jennifer, additional, O’Halloran, Alissa, additional, Patel, Kadam, additional, Pham, Huong, additional, Whitaker, Michael, additional, Reingold, Arthur, additional, Chai, Shua J., additional, Alden, Nisha B., additional, Kawasaki, Breanna, additional, Meek, James, additional, Yousey-Hindes, Kimberly, additional, Anderson, Evan J., additional, Openo, Kyle P., additional, Weigel, Andy, additional, Teno, Kenzie, additional, Reeg, Libby, additional, Leegwater, Lauren, additional, Lynfield, Ruth, additional, McMahon, Melissa, additional, Ropp, Susan, additional, Rudin, Dominic, additional, Muse, Alison, additional, Spina, Nancy, additional, Bennett, Nancy M., additional, Popham, Kevin, additional, Billing, Laurie M., additional, Shiltz, Eli, additional, Sutton, Melissa, additional, Thomas, Ann, additional, Schaffner, William, additional, Talbot, H. Keipp, additional, Crossland, Melanie T., additional, McCaffrey, Keegan, additional, Hall, Aron J., additional, Burns, Erin, additional, McMorrow, Meredith, additional, Reed, Carrie, additional, Havers, Fiona P., additional, and Garg, Shikha, additional

Published
2022
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80. Characteristics and Outcomes of Hospitalized Pregnant Women With Influenza, 2010 to 2019

Author

Holstein, Rachel, primary, Dawood, Fatimah S., additional, O’Halloran, Alissa, additional, Cummings, Charisse, additional, Ujamaa, Dawud, additional, Daily Kirley, Pam, additional, Yousey-Hindes, Kimberly, additional, Fawcett, Emily, additional, Monroe, Maya L., additional, Kim, Sue, additional, Lynfield, Ruth, additional, McMullen, Chelsea, additional, Muse, Alison, additional, Bennett, Nancy M., additional, Billing, Laurie M., additional, Sutton, Melissa, additional, Thomas, Ann, additional, Talbot, H. Keipp, additional, Schaffner, William, additional, Risk, Ilene, additional, Reed, Carrie, additional, and Garg, Shikha, additional

Published
2022
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81. Risk Factors for Severe COVID-19 in Children

Author

Woodruff, Rebecca C., primary, Campbell, Angela P., additional, Taylor, Christopher A., additional, Chai, Shua J., additional, Kawasaki, Breanna, additional, Meek, James, additional, Anderson, Evan J., additional, Weigel, Andy, additional, Monroe, Maya L., additional, Reeg, Libby, additional, Bye, Erica, additional, Sosin, Daniel M., additional, Muse, Alison, additional, Bennett, Nancy M., additional, Billing, Laurie M., additional, Sutton, Melissa, additional, Talbot, H. Keipp, additional, McCaffrey, Keegan, additional, Pham, Huong, additional, Patel, Kadam, additional, Whitaker, Michael, additional, McMorrow, Meredith, additional, and Havers, Fiona, additional

Published
2021
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83. COVID-19-Associated Hospitalizations Among Health Care Personnel--COVID-NET, 13 States, March 1-May 31, 2020

Author

Kambhampati, Anita K., O'Halloran, Alissa C., Whitaker, Michael, Magill, Shelley S., Chea, Nora, Chai, Shua J., Kirley, Pam Daily, Herlihy, Rachel K., Kawasaki, Breanna, Meek, James, Yousey-Hindes, Kimberly, Anderson, Evan J., Openo, Kyle P., Monroe, Maya L., Ryan, Patricia A., Kim, Sue, Reeg, Libby, Como-Sabetti, Kathryn, Danila, Richard, Davis, Sarah Shrum, Torres, Salina, Barney, Grant, Spina, Nancy L., Bennett, Nancy M., Felsen, Christina B., Billing, Laurie M., Shiltz, Jessica, Sutton, Melissa, West, Nicole, Schaffner, William, Talbot, H. Keipp, Chatelain, Ryan, Hill, Mary, Brammer, Lynnette, Fry, Alicia M., Hall, Aron J., Wortham, Jonathan M., Garg, Shikha, and Kim, Lindsay

Subjects
Hospital patients -- Health aspects, Evidence-based medicine -- Health aspects, Medical personnel -- Health aspects, COVID-19 -- Health aspects, Health
Abstract

On October 26, 2020, this report was posted as an MMWR Early Release on the MMWR website (https://www.cdc.gov/mmwr). Health care personnel (HCP) can be exposed to SARS-CoV-2, the virus that [...]

Published
2020

84. Characteristics and Maternal and Birth Outcomes of Hospitalized Pregnant Women with Laboratory-Confirmed COVID-19--COVID-NET, 13 States, March 1-August 22, 2020

Author

Delahoy, Miranda J., Whitaker, Michael, O'Halloran, Alissa, Chai, Shua J., Kirley, Pam Daily, Alden, Nisha, Kawasaki, Breanna, Meek, James, Yousey-Hindes, Kimberly, Anderson, Evan J., Openo, Kyle P., Monroe, Maya L., Ryan, Patricia A., Fox, Kimberly, Kim, Sue, Lynfield, Ruth, Siebman, Samantha, Davis, Sarah Shrum, Sosin, Daniel M., Barney, Grant, Muse, Alison, Bennett, Nancy M., Felsen, Christina B., Billing, Laurie M., Shiltz, Jessica, Sutton, Melissa, West, Nicole, Schaffner, William, Talbot, H. Keipp, George, Andrea, Spencer, Melanie, Ellington, Sascha, Galang, Romeo R., Gilboa, Suzanne M., Tong, Van T., Piasecki, Alexandra, Brammer, Lynnette, Fry, Alicia M., Hall, Aron J., Wortham, Jonathan M., Kim, Lindsay, and Garg, Shikha

Subjects
Pregnant women -- Health aspects, COVID-19 -- Health aspects, Health
Abstract

On September 16, 2020, this report was posted as an MMWR Early Release on the MMWR website (https://www.cdc.gov/mmwr). Pregnant women might be at increased risk for severe coronavirus disease 2019 [...]

Published
2020

87. Racial and Ethnic Disparities in Rates of COVID-19–Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death in the United States From March 2020 to February 2021

Author

Acosta, Anna M., primary, Garg, Shikha, additional, Pham, Huong, additional, Whitaker, Michael, additional, Anglin, Onika, additional, O’Halloran, Alissa, additional, Milucky, Jennifer, additional, Patel, Kadam, additional, Taylor, Christopher, additional, Wortham, Jonathan, additional, Chai, Shua J., additional, Kirley, Pam Daily, additional, Alden, Nisha B., additional, Kawasaki, Breanna, additional, Meek, James, additional, Yousey-Hindes, Kimberly, additional, Anderson, Evan J., additional, Openo, Kyle P., additional, Weigel, Andrew, additional, Monroe, Maya L., additional, Ryan, Patricia, additional, Reeg, Libby, additional, Kohrman, Alexander, additional, Lynfield, Ruth, additional, Bye, Erica, additional, Torres, Salina, additional, Salazar-Sanchez, Yadira, additional, Muse, Alison, additional, Barney, Grant, additional, Bennett, Nancy M., additional, Bushey, Sophrena, additional, Billing, Laurie, additional, Shiltz, Eli, additional, Sutton, Melissa, additional, Abdullah, Nasreen, additional, Talbot, H. Keipp, additional, Schaffner, William, additional, Ortega, Jake, additional, Price, Andrea, additional, Fry, Alicia M., additional, Hall, Aron, additional, Kim, Lindsay, additional, and Havers, Fiona P., additional

Published
2021
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88. COVID-19-associated hospitalizations among vaccinated and unvaccinated adults ≥18 years – COVID-NET, 13 states, January 1 – July 24, 2021

Author

Havers, Fiona P., primary, Pham, Huong, additional, Taylor, Christopher A., additional, Whitaker, Michael, additional, Patel, Kadam, additional, Anglin, Onika, additional, Kambhampati, Anita K., additional, Milucky, Jennifer, additional, Zell, Elizabeth, additional, Chai, Shua J., additional, Kirley, Pam Daily, additional, Alden, Nisha B., additional, Armistead, Isaac, additional, Yousey-Hindes, Kimberly, additional, Meek, James, additional, Openo, Kyle P., additional, Anderson, Evan J., additional, Reeg, Libby, additional, Kohrman, Alexander, additional, Lynfield, Ruth, additional, Como-Sabetti, Kathryn, additional, Davis, Elizabeth M., additional, Cline, Cory, additional, Muse, Alison, additional, Barney, Grant, additional, Bushey, Sophrena, additional, Felsen, Christina B., additional, Billing, Laurie M., additional, Shiltz, Eli, additional, Sutton, Melissa, additional, Abdullah, Nasreen, additional, Talbot, H. Keipp, additional, Schaffner, William, additional, Hill, Mary, additional, George, Andrea, additional, Murthy, Bhavini Patel, additional, and McMorrow, Meredith, additional

Published
2021
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89. Rates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019

Author

O’Halloran, Alissa C., primary, Holstein, Rachel, additional, Cummings, Charisse, additional, Daily Kirley, Pam, additional, Alden, Nisha B., additional, Yousey-Hindes, Kimberly, additional, Anderson, Evan J., additional, Ryan, Patricia, additional, Kim, Sue, additional, Lynfield, Ruth, additional, McMullen, Chelsea, additional, Bennett, Nancy M., additional, Spina, Nancy, additional, Billing, Laurie M., additional, Sutton, Melissa, additional, Schaffner, William, additional, Talbot, H. Keipp, additional, Price, Andrea, additional, Fry, Alicia M., additional, Reed, Carrie, additional, and Garg, Shikha, additional

Published
2021
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90. Clinical Trends Among U.S. Adults Hospitalized With COVID-19, March to December 2020 : A Cross-Sectional Study.

Author

Garg, Shikha, Garg, Shikha, Patel, Kadam, Pham, Huong, Whitaker, Michael, O'Halloran, Alissa, Milucky, Jennifer, Anglin, Onika, Kirley, Pam D, Reingold, Arthur, Kawasaki, Breanna, Herlihy, Rachel, Yousey-Hindes, Kimberly, Maslar, Amber, Anderson, Evan J, Openo, Kyle P, Weigel, Andrew, Teno, Kenzie, Ryan, Patricia A, Monroe, Maya L, Reeg, Libby, Kim, Sue, Como-Sabetti, Kathryn, Bye, Erica, Shrum Davis, Sarah, Eisenberg, Nancy, Muse, Alison, Barney, Grant, Bennett, Nancy M, Felsen, Christina B, Billing, Laurie, Shiltz, Jess, Sutton, Melissa, Abdullah, Nasreen, Talbot, H Keipp, Schaffner, William, Hill, Mary, Chatelain, Ryan, Wortham, Jonathan, Taylor, Christopher, Hall, Aron, Fry, Alicia M, Kim, Lindsay, Havers, Fiona P, Garg, Shikha, Garg, Shikha, Patel, Kadam, Pham, Huong, Whitaker, Michael, O'Halloran, Alissa, Milucky, Jennifer, Anglin, Onika, Kirley, Pam D, Reingold, Arthur, Kawasaki, Breanna, Herlihy, Rachel, Yousey-Hindes, Kimberly, Maslar, Amber, Anderson, Evan J, Openo, Kyle P, Weigel, Andrew, Teno, Kenzie, Ryan, Patricia A, Monroe, Maya L, Reeg, Libby, Kim, Sue, Como-Sabetti, Kathryn, Bye, Erica, Shrum Davis, Sarah, Eisenberg, Nancy, Muse, Alison, Barney, Grant, Bennett, Nancy M, Felsen, Christina B, Billing, Laurie, Shiltz, Jess, Sutton, Melissa, Abdullah, Nasreen, Talbot, H Keipp, Schaffner, William, Hill, Mary, Chatelain, Ryan, Wortham, Jonathan, Taylor, Christopher, Hall, Aron, Fry, Alicia M, Kim, Lindsay, and Havers, Fiona P

Abstract

BackgroundThe COVID-19 pandemic has caused substantial morbidity and mortality.ObjectiveTo describe monthly clinical trends among adults hospitalized with COVID-19.DesignPooled cross-sectional study.Setting99 counties in 14 states participating in the Coronavirus Disease 2019-Associated Hospitalization Surveillance Network (COVID-NET).PatientsU.S. adults (aged ≥18 years) hospitalized with laboratory-confirmed COVID-19 during 1 March to 31 December 2020.MeasurementsMonthly hospitalizations, intensive care unit (ICU) admissions, and in-hospital death rates per 100 000 persons in the population; monthly trends in weighted percentages of interventions, including ICU admission, mechanical ventilation, and vasopressor use, among an age- and site-stratified random sample of hospitalized case patients.ResultsAmong 116 743 hospitalized adults with COVID-19, the median age was 62 years, 50.7% were male, and 40.8% were non-Hispanic White. Monthly rates of hospitalization (105.3 per 100 000 persons), ICU admission (20.2 per 100 000 persons), and death (11.7 per 100 000 persons) peaked during December 2020. Rates of all 3 outcomes were highest among adults aged 65 years or older, males, and Hispanic or non-Hispanic Black persons. Among 18 508 sampled hospitalized adults, use of remdesivir and systemic corticosteroids increased from 1.7% and 18.9%, respectively, in March to 53.8% and 74.2%, respectively, in December. Frequency of ICU admission, mechanical ventilation, and vasopressor use decreased from March (37.8%, 27.8%, and 22.7%, respectively) to December (20.5%, 12.3%, and 12.8%, respectively); use of noninvasive respiratory support increased from March to December.LimitationCOVID-NET covers approximately 10% of the U.S. population; findings may not be generalizable to the entire country.ConclusionRates of COVID-19-associated hospitalization, ICU admission, and death were highest in December 2020, corresponding with the third peak of the U.S. pa

Published
2021

92. COVID-19 Investigational Treatments in Use Among Hospitalized Patients Identified Through the US Coronavirus Disease 2019–Associated Hospitalization Surveillance Network, March 1–June 30, 2020

Author

Acosta, Anna M, primary, Mathis, Adria L, additional, Budnitz, Daniel S, additional, Geller, Andrew I, additional, Chai, Shua J, additional, Alden, Nisha B, additional, Meek, James, additional, Anderson, Evan J, additional, Ryan, Patricia, additional, Kim, Sue, additional, Como-Sabetti, Kathryn, additional, Torres, Salina, additional, Dufort, Elizabeth, additional, Bennett, Nancy M, additional, Billing, Laurie M, additional, Sutton, Melissa, additional, Keipp Talbot, H, additional, George, Andrea, additional, Pham, Huong, additional, Hall, Aron J, additional, Fry, Alicia, additional, Garg, Shikha, additional, and Kim, Lindsay, additional

Published
2020
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93. 1712. Epidemiology, Clinical Characteristics, and Outcomes of Influenza-Associated Hospitalizations in Children in the post-2009 Pandemic Era

Author

Kamidani, Satoshi, primary, Garg, Shikha, additional, Campbell, Angela P, additional, Cummings, Charisse N, additional, Openo, Kyle P, additional, McMullen, Chelsea L, additional, Chai, Shua, additional, Herlihy, Rachel, additional, Yousey-Hindes, Kim, additional, Monroe, Maya, additional, Kim, Sue, additional, Lynfield, Ruth, additional, Dufort, Elizabeth, additional, Billing, Laurie M, additional, Sutton, Melissa, additional, Talbot, Helen, additional, McCaffrey, Keegan, additional, and Anderson, Evan J, additional

Published
2020
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94. 128. Characteristics and Outcomes of Pregnant Women Hospitalized with Influenza in the United States, Flusurv-net, 2010–2019

Author

Holstein, Rachel, primary, Dawood, Fatima S, additional, Kirley, Pam Daily, additional, Herlihy, Rachel, additional, Yousey-Hindes, Kim, additional, Fawcett, Emily, additional, Monroe, Maya, additional, Kim, Sue, additional, Lynfield, Ruth, additional, McMullen, Chelsea L, additional, Muse, Alison, additional, Billing, Laurie M, additional, Sutton, Melissa, additional, Talbot, Helen, additional, Risk, Ilene, additional, and Garg, Shikha, additional

Published
2020
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95. 1511. Influenza antiviral use in patients hospitalized with laboratory-confirmed influenza in the United States, FluSurv-NET, 2015 – 2019

Author

Tenforde, Mark W, primary, Cummings, Charisse N, additional, Sutton, Melissa, additional, Kim, Sue, additional, Maslar, Amber, additional, Alden, Nisha B, additional, Spina, Nancy, additional, Price, Andrea, additional, Monroe, Maya, additional, Rothrock, Gretchen, additional, McMahon, Melissa, additional, Talbot, Helen, additional, Openo, Kyle P, additional, McMullen, Chelsea L, additional, Billing, Laurie M, additional, and Garg, Shikha, additional

Published
2020
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97. Risk Factors for Intensive Care Unit Admission and In-hospital Mortality Among Hospitalized Adults Identified through the US Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET)

Author

Kim, Lindsay, primary, Garg, Shikha, additional, O’Halloran, Alissa, additional, Whitaker, Michael, additional, Pham, Huong, additional, Anderson, Evan J, additional, Armistead, Isaac, additional, Bennett, Nancy M, additional, Billing, Laurie, additional, Como-Sabetti, Kathryn, additional, Hill, Mary, additional, Kim, Sue, additional, Monroe, Maya L, additional, Muse, Alison, additional, Reingold, Arthur L, additional, Schaffner, William, additional, Sutton, Melissa, additional, Talbot, H Keipp, additional, Torres, Salina M, additional, Yousey-Hindes, Kimberly, additional, Holstein, Rachel, additional, Cummings, Charisse, additional, Brammer, Lynnette, additional, Hall, Aron J, additional, Fry, Alicia M, additional, and Langley, Gayle E, additional

Published
2020
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98. Interim Analysis of Risk Factors for Severe Outcomes among a Cohort of Hospitalized Adults Identified through the U.S. Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET)

Author

Kim, Lindsay, primary, Garg, Shikha, additional, O'Halloran, Alissa, additional, Whitaker, Michael, additional, Pham, Huong, additional, Anderson, Evan J., additional, Armistead, Isaac, additional, Bennett, Nancy M., additional, Billing, Laurie, additional, Como-Sabetti, Kathryn, additional, Hill, Mary, additional, Kim, Sue, additional, Monroe, Maya L., additional, Muse, Alison, additional, Reingold, Arthur, additional, Schaffner, William, additional, Sutton, Melissa, additional, Talbot, H. Keipp, additional, Torres, Salina M., additional, Yousey-Hindes, Kimberly, additional, Holstein, Rachel A, additional, Cummings, Charisse, additional, Brammer, Lynette, additional, Hall, Aron, additional, Fry, Alicia, additional, and Langley, Gayle E., additional

Published
2020
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99. Risk Factors for Severe COVID-19 in Children.

Author

Woodruff, Rebecca C., Campbell, Angela P., Taylor, Christopher A., Chai, Shua J., Kawasaki, Breanna, Meek, James, Anderson, Evan J., Weigel, Andy, Monroe, Maya L., Reeg, Libby, Bye, Erica, Sosin, Daniel M., Muse, Alison, Bennett, Nancy M., Billing, Laurie M., Sutton, Melissa, Talbot, Keipp, McCaffrey, Keegan, Pham, Huong, and MPH

Published
2022
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100. Risk Factors for Coronavirus Disease 2019 (COVID-19)–Associated Hospitalization: COVID-19–Associated Hospitalization Surveillance Network and Behavioral Risk Factor Surveillance System.

Author

Ko, Jean Y, Danielson, Melissa L, Town, Machell, Derado, Gordana, Greenlund, Kurt J, Kirley, Pam Daily, Alden, Nisha B, Yousey-Hindes, Kimberly, Anderson, Evan J, Ryan, Patricia A, Kim, Sue, Lynfield, Ruth, Torres, Salina M, Barney, Grant R, Bennett, Nancy M, Sutton, Melissa, Talbot, H Keipp, Hill, Mary, Hall, Aron J, and Fry, Alicia M

Subjects
OBESITY, CHRONIC kidney failure, HYPERTENSION, COVID-19, CONFIDENCE intervals, ASTHMA, DIABETES, RISK assessment, HOSPITAL care, DESCRIPTIVE statistics, STATISTICAL models, BEHAVIOR modification
Abstract

Background Data on risk factors for coronavirus disease 2019 (COVID-19)–associated hospitalization are needed to guide prevention efforts and clinical care. We sought to identify factors independently associated with COVID-19–associated hospitalizations. Methods Community-dwelling adults (aged ≥18 years) in the United States hospitalized with laboratory-confirmed COVID-19 during 1 March–23 June 2020 were identified from the COVID-19–Associated Hospitalization Surveillance Network (COVID-NET), a multistate surveillance system. To calculate hospitalization rates by age, sex, and race/ethnicity strata, COVID-NET data served as the numerator and Behavioral Risk Factor Surveillance System estimates served as the population denominator for characteristics of interest. Underlying medical conditions examined included hypertension, coronary artery disease, history of stroke, diabetes, obesity, severe obesity, chronic kidney disease, asthma, and chronic obstructive pulmonary disease. Generalized Poisson regression models were used to calculate adjusted rate ratios (aRRs) for hospitalization. Results Among 5416 adults, hospitalization rates (all reported as aRR [95% confidence interval]) were higher among those with ≥3 underlying conditions (vs without) (5.0 [3.9–6.3]), severe obesity (4.4 [3.4–5.7]), chronic kidney disease (4.0 [3.0–5.2]), diabetes (3.2 [2.5–4.1]), obesity (2.9 [2.3–3.5]), hypertension (2.8 [2.3–3.4]), and asthma (1.4 [1.1–1.7]), after adjusting for age, sex, and race/ethnicity. Adjusting for the presence of an individual underlying medical condition, higher hospitalization rates were observed for adults aged ≥65 or 45–64 years (vs 18–44 years), males (vs females), and non-Hispanic black and other race/ethnicities (vs non-Hispanic whites). Conclusions Our findings elucidate groups with higher hospitalization risk that may benefit from targeted preventive and therapeutic interventions. [ABSTRACT FROM AUTHOR]

Published
2021
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