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51. Predictors of Medication Adherence in the Elderly: The Role of Mental Health.

Author

Rodgers, Jo E., Thudium, Emily M., Beyhaghi, Hadi, Sueta, Carla A., Alburikan, Khalid A., Kucharska-Newton, Anna M., Chang, Patricia P., and Stearns, Sally C.

Subjects
MENTAL health, DRUGS, ATHEROSCLEROSIS, HEALTH, MILD cognitive impairment, COMPARATIVE studies, RESEARCH methodology, MEDICAL cooperation, PATIENT compliance, RESEARCH, RESEARCH funding, SELF-evaluation, SOCIOECONOMIC factors, EVALUATION research
Abstract

The aging population routinely has comorbid conditions requiring complicated medication regimens, yet nonadherence can preclude optimal outcomes. This study explored the association of adherence in the elderly with demographic, socioeconomic, and disease burden measures. Data were from the fifth visit (2011-2013) for 6,538 participants in the Atherosclerosis Risk in Communities Study, conducted in four communities. The Morisky-Green-Levine Scale measured self-reported adherence. Forty percent of respondents indicated some nonadherence, primarily due to poor memory. Logit regression showed, surprisingly, that persons with low reading ability were more likely to report being adherent. Better self-reported physical or mental health both predicted better adherence, but the magnitude of the association was greater for mental than for physical health. Compared with persons with normal or severely impaired cognition, mild cognitive impairment was associated with lower adherence. Attention to mental health measures in clinical settings could provide opportunities for improving medication adherence. [ABSTRACT FROM AUTHOR]

Published
2018
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52. Contributors

Author

Patterson, Cam, Rossi, Joseph S., Runge, Marschall S., Stouffer, George A., Abu-el-Haija, Basil, Aiken, Tiffanie, Arora, Sameer, Baker, Matthew S., Baggett, Charles, Bashore, Thomas M., Ben-Or, Sharon, Bensimhon, Hannah, Bode, Christoph, Bode, Michael, Bode, Weeranun D., Boulware, Mark E., Bowdish, Michael E., Brand, Timothy, Brodie, Bruce R., Caldwell, Adam W., Cantey, Eric P., Caranasos, Thomas G., Cascio, Wayne E., Cavender, Matthew A., Chang, Patricia P., Chien, Christopher, Chiles, Christopher D., Chung, Eugene H., Clemmons, David R., Colindres, Romulo E., Conlon, Frank L., Crowner, Jason, Dai, Xuming, Deb, Arjun, Deen, Cody S., Dehmer, Gregory J., Douglas, John S., Jr., Dupont, Allison G., El Sakr, Fredy H., Eron, Joseph J., Farber, Mark A., Ferns, Sunita Juliana, Floris-Moore, Michelle A., Ford, H. James, Foreman, Elizabeth Boger, Frantz, Elman G., Gehi, Anil K., Gettes, Leonard S., Gilbert, Olivia N., Goins, Allie E., Griffith, Anna, Griggs, Thomas R., Haithcock, Benjamin, Handberg, Eileen M., Hinderliter, Alan L., Howell, Lucius, Hummel, James P., Ivester, Thomas S., Jensen, Brian C., Jonas, Beth L., Joodi, Golsa, Katz, Jason N., Khoury, Audrey, Klein, J. Larry, Knowles, Martyn, Lee, David W., Lenihan, Daniel J., Leong, Fong T., Lluri, Gentian, Mendes, Robert, Mendys, Phil, Menon, Venu, Mill, Michael R., Miller, Paula, Mixon, Timothy A., Mounsey, J. Paul, Ohman, E. Magnus, Patel, Rikin, Patterson, Kristine B., Pauley, Eric D., Ro, Pamela S., Romero, Rachel D., Rose-Jones, Lisa J., Schofield, Richard S., Sell-Dottin, Kristen A., Sengupta, Jay D., Shaikh, Faiq, Sheikh, Arif, Sheps, David S., Sheridan, Brett C., Simpson, Ross J., Jr., Slagle, Christopher E., Smith, Sidney C., Jr., Socinski, Mark A., Stewart, Robert D., Stuckey, Thomas D., Sueta, Carla A., Tahir, Khola S., Tan, Walter A., Tate, David A., Traub, Rebecca E., Vaughn, Bradley V., Vavalle, John P., Vinnakota, Anirudh, Voora, Raven A., Weickert, Thelsa Thomas, Wessels, Andy, Wilkins, John T., Willis, Park W., IV, Yang, Eric H., Yeung, Michael, and Zurick, Andrew O., III

Published
2019
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55. Influence of Neurohormonal Antagonists on the Association of Loop Diuretic Dose with Mortality in Patients with Heart Failure: Insights From the UNITE-HF Registry

Author

Dunlap, Stephanie H., primary, Ghali, Jalal K., additional, Oren, Ron M., additional, Lee, Amanda K., additional, Piña, Ileana L., additional, Ventura, Hector O., additional, Sueta, Carla A., additional, McGrew, Frank A., additional, Patterson, J. Herbert, additional, Schwartz, Todd A., additional, and Adams, Kirkwood F., additional

Published
2016
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58. MORTALITY FOLLOWING INITIATION OR DISCONTINUATION OF GUIDELINE DIRECTED MEDICAL THERAPIES IN HOSPITALIZED HEART FAILURE PATIENTS IN THE ATHEROSCLEROSIS RISK IN COMMUNITIES STUDY

Author

Tran, Richard, primary, Aldemerdash, Ahmed, additional, Chang, Patricia, additional, Sueta, Carla, additional, Kaufman, Brystana, additional, Asafu-Adjei, Josephine, additional, Vardeny, Orly, additional, Daubert, Eliza, additional, Kucharska-Newton, Anna, additional, Stearns, Sally, additional, and Rodgers, Jo, additional

Published
2016
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59. VALIDATION OF THE ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD) POOLED COHORT RISK EQUATIONS BY EDUCATION LEVEL: THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY

Author

Henderson, Kamal Hanee, primary, Kaufman, Brystana G., additional, Stearns, Sally, additional, Couper, David, additional, Sueta, Carla, additional, Kucharska-Newton, Anna M., additional, Foraker, Randi E., additional, Asafu-Adjei, Josephine, additional, and Chang, Patricia, additional

Published
2016
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62. Sudden Cardiac Death in Patients With Ischemic Heart Failure Undergoing Coronary Artery Bypass Grafting: Results From the STICH Randomized Clinical Trial (Surgical Treatment for Ischemic Heart Failure).

Author

Rao, Meena P., Al-Khatib, Sana M., Pokorney, Sean D., She, Lilin, Romanov, Alexander, Nicolau, Jose C., Lee, Kerry L., Carson, Peter, Selzman, Craig H., Stepinska, Janina, Cleland, John G.F., Tungsubutra, Wiwun, Desvigne-Nickens, Patrice M., Sueta, Carla A., Siepe, Matthias, Lang, Irene, Feldman, Arthur M., Yii, Michael, Rouleau, Jean L., and Velazquez, Eric J.

Published
2018
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63. Antihypertensive adherence and outcomes among community‐dwelling Medicare beneficiaries: the Atherosclerosis Risk in Communities Study.

Author

Federspiel, Jerome J., Sueta, Carla A., Kucharska‐Newton, Anna M., Beyhaghi, Hadi, Zhou, Lei, Virani, Salim S., Rodgers, Jo E., Chang, Patricia P., and Stearns, Sally C.

Subjects
*ATHEROSCLEROSIS risk factors, *CLINICAL drug trials, *BLACK people, *CARDIOVASCULAR diseases risk factors, *CONCEPTUAL structures, *CONFIDENCE intervals, *DIABETES, *LENGTH of stay in hospitals, *ANTIHYPERTENSIVE agents, *LONGITUDINAL method, *MEDICARE, *HEALTH outcome assessment, *PATIENT compliance, *RACE, *REGRESSION analysis, *SEX distribution, *SMOKING, *TIME, *HEALTH insurance reimbursement, *INDEPENDENT living, *DISEASE prevalence, *ODDS ratio, EVALUATION of drug utilization
Abstract

Abstract: Rationale, aims, and objectives: Despite proven benefits for reducing incidence of major cardiac events, antihypertensive drug therapy remains underutilized in the United States. This analysis assesses antihypertensive drug adherence, utilization predictors, and associations between adherence and outcomes (a composite of cardiovascular events, Medicare inpatient payments, and inpatient days). Methods: The sample consisted of Atherosclerosis Risk in Communities Study cohort participants reporting hypertension without prevalent cardiovascular disease during 2006 to 2007 annual follow‐up calls. Atherosclerosis Risk in Communities records were linked to Medicare claims through 2012. Antihypertensive medication adherence was measured as more than 80% proportion days covered by using Medicare Part D claims. Standard and hierarchical regression models were used to evaluate adjusted associations between person characteristics and adherence and between adherence and outcomes. Results: Among 1826 hypertensive participants with Part D coverage, 31.5% had no antihypertensive class with more than 80% proportion days covered in the 3 months preceding the report of hypertension in 2006 to 2007. After adjustment for confounders, positive predictors of use included female gender and diabetes; negative predictors were African‐American race and current smoking. Adjusted association between receiving no therapy and a composite endpoint of cardiovascular outcomes through 2012 was not statistically significant (hazard ratio: 0.93; 95% confidence interval: 0.72, 1.22) nor was the adjusted association with Medicare inpatient days or payments (incremental difference at 48 months in payments: $1217; 95% CI: −$2030, $4463). Conclusions: Despite having medical and prescription coverage, nearly a third of hypertensive participants were not adherent to antihypertensive drug therapy. Differences in clinical outcomes associated with nonadherence, though not statistically significant, were consistent with results from randomized trials. The approach provides a model framework for rigorous assessment of detailed data that are increasingly available through emerging sources. [ABSTRACT FROM AUTHOR]

Published
2018
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64. Multisite Randomized Trial of a Single-Session Versus Multisession Literacy-Sensitive Self-Care Intervention for Patients With Heart Failure

Author

Jones, Christine D., MacAbasco-O'Connell, Aurelia, Pignone, Michael, Erman, Brian, Wu, Jia Rong, Cene, Crystal Wiley, Ruo, Bernice, Weinberger, Morris, Holmes, George M., Hawk, Victoria, Sueta, Carla A., Broucksou, Kimberly, Schillinger, Dean, Baker, David W., Chang, Patricia P., Grady, Kathleen L., Dewalt, Darren A., and Bibbins-Domingo, Kirsten

Subjects
fungi, food and beverages
Abstract

Self-care training can reduce hospitalization for heart failure (HF), and more intensive intervention may benefit more vulnerable patients, including those with low literacy.

Published
2012
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68. A heart failure self-management program for patients of all literacy levels: A randomized, controlled trial [ISRCTN11535170]

Author

Malone, Robert M., Bryant, Mary E., Dewalt, Darren, Pignone, Michael, Kosnar, Margaret C., Sueta, Carla A., and Corr, Kelly E.

Abstract

Background: Self-management programs for patients with heart failure can reduce hospitalizations and mortality. However, no programs have analyzed their usefulness for patients with low literacy. We compared the efficacy of a heart failure self-management program designed for patients with low literacy versus usual care. Methods: We performed a 12-month randomized controlled trial. From November 2001 to April 2003, we enrolled participants aged 30–80, who had heart failure and took furosemide. Intervention patients received education on self-care emphasizing daily weight measurement, diuretic dose self-adjustment, and symptom recognition and response. Picture-based educational materials, a digital scale, and scheduled telephone follow-up were provided to reinforce adherence. Control patients received a generic heart failure brochure and usual care. Primary outcomes were combined hospitalization or death, and heart failure-related quality of life. Results: 123 patients (64 control, 59 intervention) participated; 41% had inadequate literacy. Patients in the intervention group had a lower rate of hospitalization or death (crude incidence rate ratio (IRR) = 0.69; CI 0.4, 1.2; adjusted IRR = 0.53; CI 0.32, 0.89). This difference was larger for patients with low literacy (IRR = 0.39; CI 0.16, 0.91) than for higher literacy (IRR = 0.56; CI 0.3, 1.04), but the interaction was not statistically significant. At 12 months, more patients in the intervention group reported monitoring weights daily (79% vs. 29%, p < 0.0001). After adjusting for baseline demographic and treatment differences, we found no difference in heart failure-related quality of life at 12 months (difference = -2; CI -5, +9). Conclusion: A primary care-based heart failure self-management program designed for patients with low literacy reduces the risk of hospitalizations or death.

Published
2006
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69. Disparities in lipid management for African Americans and Caucasians with coronary artery disease: A national cross-sectional study

Author

Massing, Mark W, Carter-Edwards, Lori, Sueta, Carla A., and Simpson, Ross, Jr.

Abstract

Background Individuals with coronary artery disease are at high risk for adverse health outcomes. This risk can be diminished by aggressive lipid management, but adherence to lipid management guidelines is far from ideal and substantial racial disparities in care have been reported. Lipid treatment and goal attainment information is not readily available for large patient populations seen in the fee-for-service setting. As a result, national programs to improve lipid management in this setting may focus on lipid testing as an indicator of lipid management. We describe the detection, treatment, and control of dyslipdemia for African Americans and Caucasians with coronary artery disease to evaluate whether public health programs focusing on lipid testing can eliminate racial disparities in lipid management. Methods Physicians and medical practices with high numbers of prescriptions for coronary artery disease medications were invited to participate in the Quality Assurance Program. Medical records were reviewed from a random sample of patients with coronary artery disease seen from 1995 through 1998. Data related to the detection, treatment, and control of dyslipidemia were abstracted from the medical record and evaluated in cross-sectional stratified and logistic regression analyses using generalized estimation equations. Results Data from the medical records of 1,046 African Americans and 22,077 Caucasians seen in outpatient medical practices in 23 states were analyzed. African-American patients were younger, more likely to be women and to have diabetes, heart failure, and hypertension. The low density lipoprotein cholesterol (LDL-C) testing rate for Caucasian men was over 1.4 times higher than that for African-American women and about 1.3 times higher than that for African-American men. Almost 60% of tested Caucasian men and less than half of tested African Americans were prescribed lipid-lowering drugs. Tested and treated Caucasian men had the highest LDL-C goal attainment (35%) and African-American men the lowest (21%). Conclusions Although increased lipid testing is clearly needed for African Americans, improvements in treatment and control are also necessary to eliminate racial disparities in lipid management. Disparities in treatment and goal attainment must be better understood and reflected in policy to improve the health of underserved populations.

Published
2004
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70. Abstract 13786: Contribution of Medications and Risk Factors to QT Interval Lengthening in the Atherosclerosis Risk in Communities (ARIC) Study

Author

Alburikan, Khalid A, primary, Savitz, Samuel T, additional, Whitsel, Eric A, additional, Tisdale, James E, additional, Soliman, Elsayed Z, additional, Thudium, Emily M, additional, Sueta, Carla A, additional, Kucharska-Newton, Anna M, additional, Stearns, Sally C, additional, and Rodgers, Jo E, additional

Published
2014
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76. Comparable Ascertainment of Newly-Diagnosed Atrial Fibrillation Using Active Cohort Follow-Up versus Surveillance of Centers for Medicare and Medicaid Services in the Atherosclerosis Risk in Communities Study

Author

Bengtson, Lindsay G. S., primary, Kucharska-Newton, Anna, additional, Wruck, Lisa M., additional, Loehr, Laura R., additional, Folsom, Aaron R., additional, Chen, Lin Y., additional, Rosamond, Wayne D., additional, Duval, Sue, additional, Lutsey, Pamela L., additional, Stearns, Sally C., additional, Sueta, Carla, additional, Yeh, Hsin-Chieh, additional, Fox, Ervin, additional, and Alonso, Alvaro, additional

Published
2014
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78. Prognostic Significance of Biomarkers in Predicting Outcome in Patients With Coronary Artery Disease and Left Ventricular Dysfunction

Author

Feldman, Arthur M., primary, Mann, Douglas L., additional, She, Lilin, additional, Bristow, Michael R., additional, Maisel, Alan S., additional, McNamara, Dennis M., additional, Walsh, Ryan, additional, Lee, Dorellyn L., additional, Wos, Stanislaw, additional, Lang, Irene, additional, Wells, Gretchen, additional, Drazner, Mark H., additional, Schmedtje, John F., additional, Pauly, Daniel F., additional, Sueta, Carla A., additional, Di Maio, Michael, additional, Kron, Irving L., additional, Velazquez, Eric J., additional, and Lee, Kerry L., additional

Published
2013
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79. Multisite Randomized Trial of a Single-Session Versus Multisession Literacy-Sensitive Self-Care Intervention for Patients With Heart Failure

Author

DeWalt, Darren A., primary, Schillinger, Dean, additional, Ruo, Bernice, additional, Bibbins-Domingo, Kirsten, additional, Baker, David W., additional, Holmes, George M., additional, Weinberger, Morris, additional, Macabasco-O'Connell, Aurelia, additional, Broucksou, Kimberly, additional, Hawk, Victoria, additional, Grady, Kathleen L., additional, Erman, Brian, additional, Sueta, Carla A., additional, Chang, Patricia P., additional, Cene, Crystal Wiley, additional, Wu, Jia-Rong, additional, Jones, Christine D., additional, and Pignone, Michael, additional

Published
2012
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80. BETA-1 ADRENERGIC RECEPTOR GENOTYPE SER49GLY IS ASSOCIATED WITH BETA-BLOCKER SURVIVAL BENEFIT IN PATIENTS WITH HEART FAILURE

Author

Talameh, Jasmine, primary, Garrand, Amanda, additional, Ghali, Jalal, additional, Oren, Ron M., additional, Dunlap, Stephanie, additional, Bakel, Adrian Van, additional, Pina, Ileana, additional, Patterson, J. Herbert, additional, Sueta, Carla, additional, McGrew, Frank, additional, Miller, Alan, additional, Schwartz, Todd, additional, and Adams, Kirkwood, additional

Published
2012
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82. Quality of heart failure care in managed Medicare and Medicaid patients in North Carolina**The analyses upon which this publication is based were performed under Contract 500-02-NC03, entitled “Utilization and Quality Control Peer Review Organization for the State of North Carolina,” sponsored by the Centers for Medicare & Medicaid Services, Department of Health and Human Services. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does the mention of trade names, commercial products, or organizations imply endorsement by the U.S. Government. The investigator assumes full responsibility for the accuracy and completeness of the ideas presented. This article is a direct result of the Health Care Quality Improvement Program initiated by the Centers for Medicare & Medicaid Services, which has encouraged identification of quality improvement projects derived from analysis of patterns of care, and therefore required no special funding on the part of this contractor. Ideas and contributions to the investigator concerning experience in engaging with issues presented are welcomed.

Author

Bertoni, Alain G, primary, Duren-Winfield, Vanessa, additional, Ambrosius, Walter T, additional, McArdle, Jill, additional, Sueta, Carla A, additional, Massing, Mark W, additional, Peacock, Sharon, additional, Davis, Jennifer, additional, Croft, Janet B, additional, and Goff, David C, additional

Published
2004
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84. Impaired renal function is common in outpatients with heart failure: results from the STAMINA-HFP (study of anemia in a heart failure population) registry

Author

Ghali, Jalal K., primary, Adams, Kirkwood F., additional, Mehra, Mandeep R., additional, Pina, Ileana, additional, Wagoner, Lynn E., additional, Oren, Ron M., additional, Sueta, Carla A., additional, Dunlap, Stephanie H., additional, Gheorghiade, Mihai, additional, Cotts, William G., additional, Gattis, Wendy A., additional, George, Shelley, additional, and Patterson, J.Herbert, additional

Published
2003
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88. Effect of angiotensin-converting inhibitor or angiotensin receptor blocker on one-year survival in patients ≥65 years hospitalized with a left ventricular ejection fraction ≥50%**The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the US Government. The investigator assumes full responsibility for the accuracy and completeness of the ideas presented. This study is a direct result of the Health Care Quality Improvement Program initiated by the Centers for Medicare & Medicaid Services, which has encouraged identification of quality improvement projects derived from analysis of patterns of care, and therefore required no special funding on the part of this contractor. Ideas and contributions to the investigator concerning experience in engaging with issues presented are welcomed.

Author

Sueta, Carla A, primary, Russo, Allison, additional, Schenck, Anna, additional, Brown, David W, additional, and Simpson, Ross J, additional

Published
2003
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90. Effect of angiotensin-converting enzyme inhibitor therapy on 30-day outcome in patients ≥65 years of age with chronic congestive heart failure∗∗The analyses upon which this publication is based were performed under contract number 500-96-P613, entitled “Operation of Utilization and Quality Control Peer Review Organization (PRO) for the state of North Carolina, sponsored by the Health Care Financing Administration, Department of Health and Human Services.” The conclusions and opinions expressed, and methods used herein are those of the investigators. They do not necessarily reflect Health Care Financing Administration policy. The investigators assume full responsibility for the accuracy and completeness of the ideas presented.

Author

Sueta, Carla A, primary, Schenck, Anna, additional, Chowdhury, Mridul, additional, Hall, Randa, additional, and Simpson, Ross J, additional

Published
2000
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92. Gender Differences in Survival in Advanced Heart Failure

Author

Adams, Kirkwood F., primary, Sueta, Carla A., additional, Gheorghiade, Mihai, additional, O’Connor, Christopher M., additional, Schwartz, Todd A., additional, Koch, Gary G., additional, Uretsky, Barry, additional, Swedberg, Karl, additional, McKenna, William, additional, Soler-Soler, Jordi, additional, and Califf, Robert M., additional

Published
1999
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96. A Practical Guide for the Treatment of Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF)

Author

N. Reed, Brent and A. Sueta, Carla

Abstract

This review will outline the management of patients with symptomatic systolic heart failure or heart failure with reduced ejection fraction (HFrEF), i.e., those with structural heart disease and previous or current symptoms. Determination of volume status and appropriate diuretic administration is important in heart failure management. Inhibition of the renin-angiotensin-aldosterone and sympathetic nervous systems improves survival and decreases hospitalizations in patients with systolic or reduced ejection fraction HF (HFrEF). Beta blockers and aldosterone antagonists improve ejection fraction. Indications for additional agents including nitrates plus hydralazine, digoxin, statins, omega 3 polyunsaturated fatty acids, anticoagulants, and antiarrhythmics will be discussed. Choice of agents, dose-related effects, strategies to minimize adverse effects, and medications to avoid will be presented.

Published
2015

97. Stage A: Can Heart Failure Be Prevented?

Author

M. Danelich, Ilya, N. Reed, Brent, and A. Sueta, Carla

Abstract

Heart failure (HF) is an epidemic associated with significant morbidity and mortality, affecting over 5 million people in the United States and 1-2% of the population worldwide. Observational studies have suggested that a healthy lifestyle can reduce HF risk. Although no clinical trials have targeted the prevention of HF as a primary endpoint, many have evaluated outcomes associated with the development of symptomatic disease (i.e., progression to HF, HF hospitalization or death) as secondary endpoints. Blood pressure treatment represents the most effective strategy in preventing heart failure; each 5 mm Hg decrease in systolic blood pressures reduces the risk of HF development by 24%. Thiazide diuretics appear to be the most efficacious agents in patients with hypertension. Angiotensin converting enzyme inhibitors and angiotensin-II receptor blockers are first line agents for patients with chronic atherosclerosis, diabetes, or chronic kidney disease. Beta blockers appear less effective as single agents and cardioselective agents are preferred. Calcium channel blockers, specifically non-dihydropyridines, should be avoided and alpha blockers should not be used to reduce HF risk.

Published
2015

98. Stage B: What is the Evidence for Treatment of Asymptomatic Left Ventricular Dysfunction?

Author

N. Reed, Brent and A. Sueta, Carla

Abstract

Although patients with American College of Cardiology / American Heart Association (ACC/AHA) Stage B heart failure, or asymptomatic left ventricular dysfunction (ALVD) are at high risk for developing symptomatic heart failure, few management strategies have been shown to slow disease state progression or improve long-term morbidity and mortality. Of the pharmacologic therapies utilized in patients with symptomatic disease, only angiotensin converting enzyme (ACE) inhibitors (and to a lesser extent, angiotensin receptor blockers, or ARBs) have been shown to improve clinical outcomes among patients with ALVD. Although evidence to support the use of beta blockers in this setting has been primarily derived from retrospective studies or subgroup analyses, they are generally recommended in most patients with ALVD, especially those with ischemic etiology. Statins are associated with improvements in both major adverse cardiovascular events and heart failure events among patients with a history of acute myocardial infarction. Finally, in eligible patients, placement of an automatic implantable cardioverter defibrillator (ICD) has been associated with reduced mortality rates among those with ALVD due to ischemic cardiomyopathy, and some subgroups may derive benefit from cardiac resynchronization therapy or biventricular pacing.

Published
2015

99. Safety and efficacy of epoprostenol in patients with severe congestive heart failure

Author

Sueta, Carla A., primary, Gheorghiade, Mihai, additional, Adams, Kirkwood F., additional, Bourge, Robert C., additional, Murali, Srinivas, additional, Uretsky, Barry F., additional, Pritzker, Marc R., additional, McGoon, Michael D., additional, Butman, Samuel M., additional, Grossman, Steven H., additional, Crow, James W., additional, Shaffer, Christy L., additional, and Thorn, Michael D., additional

Published
1995
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