Search

Your search keyword '"Sudo, Akihiro"' showing total 1,670 results
Start Over Author "Sudo, Akihiro"
1,670 results on '"Sudo, Akihiro"'

64. Neuropathic pain in patients with osteoarthritis of the hip before and after total hip arthroplasty.

Author

Yamabe, Yohei, Hasegawa, Masahiro, Kobayashi, Gai, Tone, Shine, Naito, Yohei, and Sudo, Akihiro

Subjects
TOTAL hip replacement, HIP osteoarthritis, NEURALGIA, NOCICEPTIVE pain
Abstract

Objectives: The pain associated with osteoarthritis (OA) was thought to be nociceptive; however, neuropathic pain is also observed. We investigated the relationship between hip OA and neuropathic pain using the PainDETECT questionnaire (PDQ). Methods: A total of 159 hips of 146 consecutive patients who underwent total hip arthroplasty (THA) with a diagnosis of OA were enrolled in this study. The prevalence of each pain phenotype was evaluated preoperatively and at 6 months postoperatively using the PDQ. Patient characteristics and numerical rating scale (NRS) scores were compared between a group with possible neuropathic pain (NP group) and a group with nociceptive pain (non-NP group). Results: Before THA, neuropathic, unclear, and nociceptive pain was observed in 18, 36, and 105 hips, respectively. The prevalence in the NP group was 54 hips, accounting for approximately one-third of all hips, which decreased significantly to seven hips after THA. A significantly higher NRS score was observed in the NP group, both before and after THA. Conclusion: Approximately one-third of the patients with hip OA had neuropathic pain. Therefore, neuropathic pain should be considered when treating patients with hip OA. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

79. Effect of autologous platelet-rich plasma-releasate on intervertebral disc degeneration in the rabbit anular puncture model: a preclinical study

Author

Obata, Shuji, Akeda, Koji, Imanishi, Takao, Masuda, Koichi, Bae, Won, Morimoto, Ryo, Asanuma, Yumiko, Kasai, Yuichi, Uchida, Atsumasa, and Sudo, Akihiro

Abstract

Abstract Introduction Platelet-rich plasma (PRP) is a fraction of plasma in which several growth factors are concentrated at high levels. The active soluble releasate isolated following platelet activation of PRP (PRP-releasate) has been demonstrated to stimulate the metabolism of IVD cells in vitro. The in vivo effect of PRP-releasate on degenerated IVD remains unknown. The purpose of this study was to determine the reparative effects of autologous PRP-releasate on degenerated intervertebral discs (IVDs). Methods To induce disc degeneration, New Zealand white rabbits (n = 12) received anular puncture in two noncontiguous discs. Autologous PRP and PPP (platelet-poor plasma) were isolated from fresh blood using two centrifugation techniques. Four weeks after the initial puncture, releasate isolated from clotted PPP or PRP (PPP- or PRP-releasate), or phosphate-buffered saline (PBS; control) was injected into the punctured discs. Disc height, magnetic resonance imaging (MRI) T2-mapping and histology were assessed. Results Anular puncture produced a consistent disc narrowing within four weeks. PRP-releasate induced a statistically significant restoration of disc height (PRP vs. PPP and PBS, P

Published
2012

Catalog

Books, media, physical & digital resources
See catalog results