Search

Your search keyword '"Suderman, Matthew"' showing total 908 results
Start Over Author "Suderman, Matthew"
908 results on '"Suderman, Matthew"'

54. Identifying epigenetic biomarkers of established prognostic factors and survival in a clinical cohort of individuals with oropharyngeal cancer

Author

Langdon, Ryan, Richmond, Rebecca, Elliott, Hannah R., Dudding, Tom, Kazmi, Nabila, Penfold, Chris, Ingarfield, Kate, Ho, Karen, Bretherick, Andrew, Haley, Chris, Zeng, Yanni, Walker, Rosie M., Pawlita, Michael, Waterboer, Tim, Gaunt, Tom, Smith, George Davey, Suderman, Matthew, Thomas, Steve, Ness, Andy, and Relton, Caroline

Published
2020
Full Text
View/download PDF

60. Characterization of neurotropic HPAI H5N1 viruses with novel genome constellations and mammalian adaptive mutations in free-living mesocarnivores in Canada.

Author

Alkie, Tamiru N., Cox, Sherri, Embury-Hyatt, Carissa, Stevens, Brian, Pople, Neil, Pybus, Margo J., Xu, Wanhong, Hisanaga, Tamiko, Suderman, Matthew, Koziuk, Janice, Kruczkiewicz, Peter, Nguyen, Hoang Hai, Fisher, Mathew, Lung, Oliver, Erdelyan, Cassidy N. G., Hochman, Orie, Ojkic, Davor, Yason, Carmencita, Bravo-Araya, Maria, and Bourque, Laura

Published
2023
Full Text
View/download PDF

61. Epigenetic Patterns Modulate the Connection between Developmental Dynamics of Parenting and Offspring Psychosocial Adjustment

Author

Naumova, Oksana Yu, Hein, Sascha, and Suderman, Matthew

Abstract

This study attempted to establish and quantify the connections between parenting, offspring psychosocial adjustment, and the epigenome. The participants, 35 African American young adults (19 females and 16 males; age = 17-29.5 years), represented a subsample of a 3-wave longitudinal 15-year study on the developmental trajectories of low-income urban mother-offspring dyads. Mothers were assessed on their perceptions of maternal stress at each wave. Offspring were assessed on their perceptions of maternal parenting at each wave and on their adaptive and maladaptive behavior at the last wave. Genome-wide DNA methylation in peripheral T lymphocytes at the third wave was assayed using Methyl Binding Domain(MBD) sequencing. Statistically significant associations were identified between the change in offspring's perception of parenting from middle childhood to adulthood and the DNA methylation in offspring's adult genomes. Specifically, the slope of perceived parental rejection across the 3 time points was related to an increase in methylation, or a potential downregulation, of 565 genes thought to be involved in the control of a broad spectrum of biological functions generally related to cellular signaling. A subset of these epigenetic marks, clustered in 23 genes, some of which participate in the development and functioning of the CNS, were in turn associated with psychosocial adjustment as captured by interpersonal relationships and emotional self-evaluation. This appears to be one of the first investigations of the modulating role of the methylome in associations between developmental dynamics of parenting throughout the formative years of child and adolescent development and psychosocial adjustment in adulthood.

Published
2016
Full Text
View/download PDF

62. Genetic impacts on DNA methylation help elucidate regulatory genomic processes

Author

Villicana, Sergio, primary, Castillo-Fernandez, Juan, additional, Hannon, Eilis, additional, Christiansen, Colette, additional, Tsai, Pei-Chien, additional, Maddock, Jane, additional, Kuh, Diana, additional, Suderman, Matthew, additional, Power, Christine, additional, Relton, Caroline, additional, Ploubidis, George, additional, Wong, Andrew, additional, Hardy, Rebecca, additional, Goodman, Alissa, additional, Ong, Ken K., additional, and Bell, Jordana T., additional

Published
2023
Full Text
View/download PDF

63. Supplementary Table 2 from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

64. Supplementary Figure 4 from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

65. Supplementary Figure 8 from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

66. Supplementary Figure 6 from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

67. Supplementary Figure 5 from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

68. Supplementary Figure 7 from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

69. Supplementary Materials and Methods, Figure Legends, Table Legends from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

70. Supplementary Figure 3 from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

71. Supplementary Table 1 from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

72. Supplementary Figure 1 from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

73. Supplementary Figure 2 from Genome-Wide Study of Hypomethylated and Induced Genes in Patients with Liver Cancer Unravels Novel Anticancer Targets

Author

Stefanska, Barbara, primary, Cheishvili, David, primary, Suderman, Matthew, primary, Arakelian, Ani, primary, Huang, Jian, primary, Hallett, Michael, primary, Han, Ze-Guang, primary, Al-Mahtab, Mamun, primary, Akbar, Sheikh Mohammad Fazle, primary, Khan, Wasif Ali, primary, Raqib, Rubhana, primary, Tanvir, Imrana, primary, Khan, Haseeb Ahmed, primary, Rabbani, Shafaat A., primary, and Szyf, Moshe, primary

Published
2023
Full Text
View/download PDF

98. Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium

Author

Chen, Ling-Wei, Aubert, Adrien M., Shivappa, Nitin, Bernard, Jonathan Y., Mensink-Bout, Sara M., Geraghty, Aisling A., Mehegan, John, Suderman, Matthew, Polanska, Kinga, Hanke, Wojciech, Trafalska, Elzbieta, Relton, Caroline L., Crozier, Sarah R., Harvey, Nicholas C., Cooper, Cyrus, Duijts, Liesbeth, Heude, Barbara, Hébert, James R., McAuliffe, Fionnuala M., Kelleher, Cecily C., and Phillips, Catherine M.

Subjects
Birth weight, Low -- Risk factors, Pregnant women -- Food and nutrition, Gestational age -- Health aspects, Prenatal influences -- Health aspects, Diet -- Health aspects, Biological sciences
Abstract

Background Adverse birth outcomes are major causes of morbidity and mortality during childhood and associate with a higher risk of noncommunicable diseases in adult life. Maternal periconception and antenatal nutrition, mostly focusing on single nutrients or foods, has been shown to influence infant birth outcomes. However, evidence on whole diet that considers complex nutrient and food interaction is rare and conflicting. We aim to elucidate the influence of whole-diet maternal dietary inflammatory potential and quality during periconceptional and antenatal periods on birth outcomes. Methods and findings We harmonized and pooled individual participant data (IPD) from up to 24,861 mother-child pairs in 7 European mother-offspring cohorts [cohort name, country (recruitment dates): ALSPAC, UK (1 April 1991 to 31 December 1992); EDEN, France (27 January 2003 to 6 March 2006); Generation R, the Netherlands (1 April 2002 to 31 January 2006); Lifeways, Ireland (2 October 2001 to 4 April 2003); REPRO_PL, Poland (18 September 2007 to 16 December 2011); ROLO, Ireland (1 January 2007 to 1 January 2011); SWS, United Kingdom (6 April 1998 to 17 December 2002)]. Maternal diets were assessed preconceptionally (n = 2 cohorts) and antenatally (n = 7 cohorts). Maternal dietary inflammatory potential and quality were ranked using the energy-adjusted Dietary Inflammatory Index (E-DII) and Dietary Approaches to Stop Hypertension (DASH) index, respectively. Primary outcomes were birth weight and gestational age at birth. Adverse birth outcomes, i.e., low birth weight (LBW), macrosomia, small-for-gestational-age (SGA), large-for-gestational-age (LGA), preterm and postterm births were defined according to standard clinical cutoffs. Associations of maternal E-DII and DASH scores with infant birth outcomes were assessed using cohort-specific multivariable regression analyses (adjusted for confounders including maternal education, ethnicity, prepregnancy body mass index (BMI), maternal height, parity, cigarettes smoking, and alcohol consumption), with subsequent random-effects meta-analyses. Overall, the study mothers had a mean ± SD age of 29.5 ± 4.9 y at delivery and a mean BMI of 23.3 ± 4.2 kg/m.sup.2 . Higher pregnancy DASH score (higher dietary quality) was associated with higher birth weight [[beta](95% CI) = 18.5(5.7, 31.3) g per 1-SD higher DASH score; P value = 0.005] and head circumference [0.03(0.01, 0.06) cm; P value = 0.004], longer birth length [0.05(0.01, 0.10) cm; P value = 0.010], and lower risk of delivering LBW [odds ratio (OR) (95% CI) = 0.89(0.82, 0.95); P value = 0.001] and SGA [0.87(0.82, 0.94); P value < 0.001] infants. Higher maternal prepregnancy E-DII score (more pro-inflammatory diet) was associated with lower birth weight [[beta](95% CI) = -18.7(-34.8, -2.6) g per 1-SD higher E-DII score; P value = 0.023] and shorter birth length [-0.07(-0.14, -0.01) cm; P value = 0.031], whereas higher pregnancy E-DII score was associated with a shorter birth length [-0.06(-0.10, -0.01) cm; P value = 0.026] and higher risk of SGA [OR(95% CI) = 1.18(1.11, 1.26); P value < 0.001]. In male, but not female, infants higher maternal prepregnancy E-DII was associated with lower birth weight and head circumference, shorter birth length, and higher risk of SGA (P-for-sex-interaction = 0.029, 0.059, 0.104, and 0.075, respectively). No consistent associations were observed for maternal E-DII and DASH scores with gestational age, preterm and postterm birth, or macrosomia and LGA. Limitations of this study were that self-reported dietary data might have increased nondifferential measurement error and that causality cannot be claimed definitely with observational design. Conclusions In this cohort study, we observed that maternal diet that is of low quality and high inflammatory potential is associated with lower offspring birth size and higher risk of offspring being born SGA in this multicenter meta-analysis using harmonized IPD. Improving overall maternal dietary pattern based on predefined criteria may optimize fetal growth and avert substantial healthcare burden associated with adverse birth outcomes., Author(s): Ling-Wei Chen 1,*, Adrien M. Aubert 2, Nitin Shivappa 3,4, Jonathan Y. Bernard 2,5, Sara M. Mensink-Bout 6,7, Aisling A. Geraghty 8, John Mehegan 1, Matthew Suderman 9, Kinga [...]

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results