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321 results on '"Stachewicz, Urszula"'

56. Electrospun fibers as carriers for topical drug delivery and release in skin bandages and patches for atopic dermatitis treatment.

Author

Krysiak, Zuzanna J. and Stachewicz, Urszula

Abstract

The skin is a complex layer system and the most important barrier between the environment and the organism. In this review, we describe some widespread skin problems, with a focus on eczema, which are affecting more and more people all over the world. Most of treatment methods for atopic dermatitis (AD) are focused on increasing skin moisture and protecting from bacterial infection and external irritation. Topical and transdermal treatments have specific requirements for drug delivery. Breathability, flexibility, good mechanical properties, biocompatibility, and efficacy are important for the patches used for skin. Up to today, electrospun fibers are mostly used for wound dressing. Their properties, however, meet the requirements for skin patches for the treatment of AD. Active agents can be incorporated into fibers by blending, coaxial or side‐by‐side electrospinning, and also by physical absorption post‐processing. Drug release from the electrospun membranes is affected by drug and polymer properties and the technique used to combine them into the patch. We describe in detail the in vitro release mechanisms, parameters affecting the drug transport, and their kinetics, including theoretical approaches. In addition, we present the current research on skin patch design. This review summarizes the current extensive know‐how on electrospun fibers as skin drug delivery systems, while underlining the advantages in their prospective use as patches for atopic dermatitis. This article is categorized under:Implantable Materials and Surgical Technologies > Nanomaterials and ImplantsImplantable Materials and Surgical Technologies > Nanotechnology in Tissue Repair and ReplacementTherapeutic Approaches and Drug Discovery > Emerging Technologies [ABSTRACT FROM AUTHOR]

Published
2023
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62. Smart Textile for Building and Living.

Author

Priniotakis, Georgios, Marrot, Laetitia, Stachewicz, Urszula, Krstic-Furundzic, Aleksandra, Venturini, Enrico, and Jonaitiene, Vaida

Subjects
ELECTROTEXTILES, INTELLIGENT buildings, COST of living, CONSTRUCTION materials, CONCRETE mixing, POLYESTER fibers, POLYVINYL chloride, SMART materials, GLASS fibers
Abstract

In construction, textiles can be used either for reinforcing the structure or for finishing design. When we talk about function, the interior is no less important than the exterior and architecture of the building. Thus using textiles to reinforce the structure of buildings, textiles often perform a desired function of reinforcing the "finish." Building textile materials include fibers that are mixed with concrete, fiberglass reinforcement meshes, insulators, etc. Textile architecture covers permanent tensile structures based on polyester or glass fiber fabrics, with polyvinyl chloride (PVC) or polytetrafluoroethylene (PTFE) coating and awnings generally supported by polyester or polyolefin fabrics, with or without coating, especially for gardening. All above topics are covered within this perspective with the experts from the group of smart textiles for building and living within COST Action CA17107 European Network to Connect Research and Innovation Efforts on Advanced Smart Textiles (CONTEXT) [1]. [ABSTRACT FROM AUTHOR]

Published
2022
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67. Surface Potential Driven Water Harvesting from Fog

Author

Ura, Daniel P., primary, Knapczyk-Korczak, Joanna, additional, Szewczyk, Piotr K., additional, Sroczyk, Ewa A., additional, Busolo, Tommaso, additional, Marzec, Mateusz M., additional, Bernasik, Andrzej, additional, Kar-Narayan, Sohini, additional, and Stachewicz, Urszula, additional

Published
2021
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80. The Role of Electrical Polarity in Electrospinning and on the Mechanical and Structural Properties of As-Spun Fibers

Author

Ura, Daniel P., primary, Rosell-Llompart, Joan, additional, Zaszczyńska, Angelika, additional, Vasilyev, Gleb, additional, Gradys, Arkadiusz, additional, Szewczyk, Piotr K., additional, Knapczyk-Korczak, Joanna, additional, Avrahami, Ron, additional, Šišková, Alena O., additional, Arinstein, Arkadii, additional, Sajkiewicz, Paweł, additional, Zussman, Eyal, additional, and Stachewicz, Urszula, additional

Published
2020
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84. Enhanced Piezoelectricity of Electrospun Polyvinylidene Fluoride Fibers for Energy Harvesting

Author

Szewczyk, Piotr K., primary, Gradys, Arkadiusz, additional, Kim, Sung Kyun, additional, Persano, Luana, additional, Marzec, Mateusz, additional, Kryshtal, Aleksandr, additional, Busolo, Tommaso, additional, Toncelli, Alessandra, additional, Pisignano, Dario, additional, Bernasik, Andrzej, additional, Kar-Narayan, Sohini, additional, Sajkiewicz, Paweł, additional, and Stachewicz, Urszula, additional

Published
2020
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100. Effect of Porous and Nonporous Polycaprolactone Fiber Meshes on CaCO3Crystallization Through a Gas Diffusion Method

Author

Sepúlveda, Felipe, Butto, Nicole, Arias, José Luis, Yazdani-Pedram, Mehrdad, Szewczyk, Piotr K., Gruszczynski, Adam, Stachewicz, Urszula, and Neira-Carrillo, Andrónico

Abstract

The effect of nonporous (NP-PCL) and porous (P-PCL) fibrous polycaprolactone (PCL) meshes, used as templates, on in vitroCaCO3crystallization via a gas diffusion (GD) method at 20 °C for 24 h was studied. The nonporous random (NPR-PCL) and porous random (PR-PCL) and the nonporous-aligned (NPA-PCL) and porous-aligned (PA-PCL) fibrous PCL meshes were directly spun on flat or rotary collectors from 18% PCL solutions using ethyl acetate/acetone or ethyl acetate/dimethyl sulfoxide, respectively. The morphology and type of CaCO3crystal grown on PCL fiber scaffolds were analyzed by Fourier transform infrared spectroscopy (FTIR), contact angle measurements, scanning electron microscopy coupled with energy dispersive X-ray spectroscopy (SEM-EDS), focused ion beam combined with scanning electron microscopy (FIB-SEM), and X-ray diffraction (XRD) techniques. The PCL fibers distributions affected the nucleation and stabilized calcite and vaterite polymorphs of CaCO3with different crystal population densities. The crystal density of vaterite was higher than calcite (2:1) when the NPA-PCL and PA-PCL fibers were used as a template, but calcite predominated (2:1) on P-PCL fiber mesh with respect to the NP-PCL fiber mesh. We found that CaCO3crystals covered the surface of PCL fibers, and some of them grown from inside of the PCL fibers showed that PCL fibers were occluded inside the CaCO3crystals during the GD crystallization. The nano- and microscale topological features of PCL scaffolds control the diffusion of carbon dioxide (CO2) gas through PCL fiber meshes in the soaking of PCL meshes into a calcium chloride (CaCl2) solution during the GD crystallization affecting subsequently the nucleation and growth of CaCO3crystals. Indeed, pore size feature of the micrometric A-PCL and nanometric R-PCL fiber meshes affected the intensities of the crystallographic faces of calcite and vaterite as observed by XRD. Contact angle measurements of the aqueous and crystallization liquid droplet on NPR-PCL, PR-PCL and A-PCL fibrous showed different hydrophobic character of the PCL meshes. This study shows the role of the nano- and microscale topological features and the presence of pores on PCL fiber scaffolds on the mineralization behavior of CaCO3deposited on R-PCL and A-PCL fiber scaffolds, and by this approach various aspects of controlled CaCO3crystallization such as nucleation and crystal growth of biomaterials based on CaCO3can be studied with potential biotech applications.

Published
2020
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