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Objective: To analyze changes over time and the predictive value of baseline and changes of sedentary time (ST) and physical activity (PA) on pain, disease impact, and health‐related quality of life (HRQoL) at 2‐ and 5‐year follow‐up in women with fibromyalgia. Methods: This is a longitudinal and exploratory study with three time points. A total of 427 women with fibromyalgia (51.4 ± 7.6 years) were followed after 2 (n = 172) and 5 years (n = 185). ST and PA (light and moderate‐to‐vigorous [MVPA]) were assessed using triaxial accelerometers. Pain, disease impact, and HRQoL were measured using: pressure pain threshold, the pain subscale of the revised fibromyalgia impact questionnaire (FIQR), the bodily pain subscale of the 36‐item short‐form health survey (SF‐36), a visual analog scale (VAS), the FIQR, and the SF‐36 physical and mental components. Results: Over 5 years, pressure pain threshold, ST, light PA, and MVPA variables were worsened, while FIQR and SF‐36 variables were improved (Cohen's d < 0.1–0.3). Baseline ST or light PA were not associated with future outcomes, whereas greater MVPA at baseline was associated with better SF‐36 bodily pain at 5‐year follow‐up (β = 0.13). Reducing ST and increasing light PA were associated with better bodily pain (β = −0.16 and 0.17, respectively) and SF‐36 physical component (β = −0.20 and 0.17, respectively) at 5‐year follow‐up. Increasing MVPA was associated with less pain (pressure pain threshold, VAS, and FIQR‐pain) and better SF‐36 physical component at 2‐ and 5‐year follow‐up (β's from −0.20 to 0.21). Conclusions: Objectively measured variables slightly worsened over years, while for self‐reported outcomes there was a trend for improvement. Reductions in ST and increases in light PA and MVPA were associated with better HRQoL at 5‐year follow‐up, and increases in MVPA were additionally associated with better pain and HRQoL at 2‐year follow‐up. [ABSTRACT FROM AUTHOR]

This study examined which mechanical variables derived from a vertical jump (i.e. concentric peak force [ConcPF] and eccentric peak force [EccPF], flight time [FT]: contraction time [CT], eccentric deceleration rate of force development [EccDecRFD]) and linear sprint (i.e. theoretical maximal force [F0] and velocity [V0], maximal power output [Pmax], the peak ratio of the effective horizontal component [RFpeak], and the index of force application technique [DRF]) determined the change of direction (COD) performance to a greater extent. Sixteen male soccer players (age: 21.8 ± 2.9 years; height: 175.94 ± 6.88 cm; weight: 73.23 ± 9.59 kg) were assessed for a countermovement jump, the horizontal force velocity (FV) profile, and the COD ZigZag test. The horizontal FV profile parameters were significantly associated with COD performance, while jump mechanical variables did not show any significant association (r = 0.08–0.19; p > 0.05). Specifically, F0 (r = −0.56), Pmax (r = −0.68), and RFpeak (r = −0.54) were strongly associated with COD performance. Moreover, a 1 N·kg−1 increase in F0 was associated with −0.11 s to complete the ZigZag test, whereas 1 W·kg−1 and 1% increase in Pmax and RFpeak were associated with −0.05 and −0.03 s, respectively, to complete the COD test. Horizontal force production during sprinting might play a key role in COD performance. Assessing the horizontal FV profile might help coaches to prescribe a specific training programme to maximize sprint acceleration, which might improve COD performance. [ABSTRACT FROM AUTHOR]

The aims of this study were: (i) to analyse the load-velocity relationship in the bilateral leg-press exercise in female breast cancer survivors, (ii) to assess whether mean velocity (MV) or peak velocity (PV) show stronger relationship with the relative load, and (iii) to examine whether linear (LA) or polynomic (PA) adjustment predict the velocities associated with each %1RM with greater precision. Twenty-two female breast cancer survivors (age: 50.2 ± 10.8 years, weight: 69.6 ± 15.2 kg, height: 160.51 ± 5.25 cm) completed an incremental load test until 1RM in the bilateral leg-press exercise. The MV and the PV of the concentric phase were measured in each repetition using a linear velocity transducer, and were analysed by regression models using LA and PA. A very close relationship of MV (R2 = 0.924; p < 0.0001; SEE = 0.08m.s−1 by LA, and R² = 0.952; p < 0.0001; SEE = 0.063 m.s−1 by PA) and PV (R² = 0.928; p < 0.0001; SEE = 0.119 m.s−1 by LA and R² = 0.941; p < 0.0001; SEE = 0.108 m.s−1 by PA) with %1RM were observed. The MV of 1RM was 0.24 ± 0.03 m·s−1, whereas the PV at 1RM was 0.60 ± 0.10 m.s−1. A comprehensive analysis of the bilateral leg-press load-velocity relationship in breast cancer survivors is presented. The results suggest that MV is the most recommendable velocity variable to prescribe the relative load during resistance training, and that the PA presents better accuracy to predict velocities associated with each %1RM, although LA is sufficiently valid to use this model as an alternative to the quadratic model. The implications for resistance training in breast cancer are discussed. Highlights The load-velocity relationship in the bilateral leg-press exercise was described in female breast cancer survivors. The mean velocity is the most recommendable velocity variable to prescribe the relative load during resistance training in this population. The polynomial adjustment presents a better accuracy to predict velocities associated with each %1RM, although the linear adjustment is sufficiently valid as an alternative. This study will likely contribute to improving exercise prescription and monitoring in breast cancer survivors. [ABSTRACT FROM AUTHOR]

Baena-Raya, A, Jiménez-Reyes, P, Romea, ES, Soriano-Maldonado, A, and Rodríguez-Pérez, MA. Gender-specific association of the sprint mechanical properties with change of direction performance in basketball. J Strength Cond Res 36(10): 2868–2874, 2022—We evaluated the gender-specific associations between the mechanical variables derived from the horizontal force-velocity (FV) profile (i.e., theoretical maximal force [ F 0], velocity [ V 0], maximal power output [ P max ], peak ratio of the effective horizontal component [ RF peak ], and the force application technique index [ D RF ]) and the change of direction (COD) performance for basketball players. Seventy-one players (23 women and 48 men) were assessed for the horizontal FV profile and COD using the modified 505 and V-cut tests. The FV profile parameters were significantly higher for the men than those for the women. The F 0 , RF peak , and P max were strongly associated with performance in the 505 test (women r range = −0.72 to −0.82; men: r range = −0.67 to −0.75; p < 0.001) and the V-cut test (women r range = −0.68 to −0.76; men r range = −0.45 to −0.50; p < 0.001), as well as with a lower COD deficit (women r range = 0.58 to 0.75 (p < 0.01); men r range = 0.49 to 0.54; all p < 0.001). For the women, a 1 N·kg−1 increase of the F 0 was associated with −0.20 seconds and −0.56 seconds in the 505 and V-cut tests, respectively, and 0.16 seconds for the COD deficit. In the men, it was associated with −0.13 seconds and −0.37 seconds in the 505 and V-cut tests, respectively, and 0.10 seconds for the COD deficit. F 0 , RF peak , and P max are the most determinant sprint mechanical properties to successfully COD and reduce the COD deficit. The horizontal FV profile assessment is recommended for diagnosing and prescribing a training program for basketball players. [ABSTRACT FROM AUTHOR]

This study aimed to examine the association between active commuting and sedentary time (ST) and physical activity (PA) in women with fibromyalgia. This cross-sectional study included 420 women with fibromyalgia (aged 30 to 74 years old) from Spain. The participants wore an accelerometer during seven days to record ST and PA. They also self-reported patterns of active commuting. Linear regression analyses were conducted to examine the relationships between commuting and accelerometer outcomes. Age, pressure pain threshold, and accelerometer wear time were used as confounders. There was a negative association between active commuting and ST whereas active commuting was positively associated with moderate PA, moderate-to-vigorous PA, total PA, and step count (all p ≤ 0.01). No associations were observed in the older group. Younger women with fibromyalgia who were active commuters spent less ST and were involved in greater PA than passive commuters. This study highlights the importance of promoting active commuting to increase PA among young women with fibromyalgia, while other sources of PA might be recommended for older patients if levels of active commuting are not increased. Active commuting is a source to increase PA in women with fibromyalgia. Active commuting alone does not seem to be enough to increase PA levels in older women with fibromyalgia and additional PA strategies should be implemented. Promotion of active commuting in young women with fibromyalgia is recommended. [ABSTRACT FROM AUTHOR]

Objectives It is widely acknowledged that the experience of pain is promoted by both genetic susceptibility and environmental factors such as engaging in physical activity (PA), and that pain-related cognitions are also important. Thus, the purpose of the present study was to test the association of 64 polymorphisms (34 candidate genes) and the gene–gene, gene–PA and gene–sedentary behaviour interactions with pain and pain-related cognitions in women with FM. Methods Saliva samples from 274 women with FM [mean (s. d.) age 51.7 (7.7) years] were collected for extracting DNA. We measured PA and sedentary behaviour by accelerometers for a week, pain with algometry and questionnaires, and pain-related cognitions with questionnaires. To assess the robustness of the results, a meta-analysis was also performed. Results The rs6311 and rs6313 polymorphisms (5-hydroxytryptamine receptor 2A, HTR2A) were individually related to algometer scores. The interaction of rs4818 (catechol-O-methyltransferase, COMT) and rs1799971 (opioid receptor μ gene, OPRM1) was related to pain catastrophizing. Five gene–behaviour interactions were significant: the interactions of sedentary behaviour with rs1383914 (adrenoceptor alpha 1A, ADRA1A), rs6860 (charged multivesicular body protein 1A, CHMP1A), rs4680 (COMT), rs165599 (COMT) and rs12994338 (SCN9A) on bodily pain subscale of the Short Form 36. Furthermore, the meta-analysis showed an association between rs4680 (COMT) and severity of FM symptoms (codominant model, P -value 0.032). Conclusion The HTR2A gene (individually), COMT and OPRM1 gene–gene interaction, and the interactions of sedentary behaviour with ADRA1A , CHMP1A , COMT and SCN9A genes were associated with pain-related outcomes. Collectively, findings from the present study indicate a modest contribution of genetics and gene–sedentary behaviour interaction to pain and pain catastrophizing in women with FM. Future research should examine whether reducing sedentary behaviour is particularly beneficial for reducing pain in women with genetic susceptibility to pain. [ABSTRACT FROM AUTHOR]

To evaluate the effects of aerobic exercise on patient-reported outcomes (PROs) in women with systemic lupus erythematosus (SLE), and whether changes in cardiorespiratory fitness (CRF) mediate the changes in PROs. A total of 58 women with SLE were assigned to either an exercise group (EG; n = 26) or a control group (CG; n = 32) in this non-randomized clinical trial. The EG comprised 12 weeks of aerobic exercise (2 sessions/week) between 40%-75% of the individual's heart rate reserve. At baseline, and at week 12, CRF (Bruce test) and PROs were assessed including psychological stress (Perceived Stress Scale), sleep quality (Pittsburg Sleep Quality Index), fatigue (Multidimensional Fatigue Inventory), depressive symptoms (Beck Depression Inventory), and quality of life (36-item Short-Form Health Survey). In comparison to the CG, the EG showed a significant reduction in general fatigue (mean difference (MD) −2.86 units; 95%CI −5.70 to −0.01; p = 0.049), physical fatigue (MD −4.33 units; 95%CI −7.02 to −1.65; p = 0.002) and a non-significant reduction of reduced motivation (MD − 1.29 units; 95%CI −2.60 to 0.03; p = 0.055). There were no significant between-group differences in the changes in psychological stress, sleep quality, depressive symptoms, quality of life, or other fatigue dimensions (all p > 0.05). Changes in CRF mediated the effects of the exercise intervention on general fatigue by 53.8%. The results suggest that 12 weeks of progressive aerobic exercise might improve relevant dimensions of fatigue in women with SLE, despite the absence of effects on other PROs. Improvements in CRF seem to mediate the effect of exercise on general fatigue. Aerobic exercise could be safely introduced in rehabilitation programs for inactive patients with SLE with mild disease activity. Including physical activity recommendations as part of rehabilitation could improve relevant aspects of fatigue in women with SLE. When rehabilitation aims at reducing fatigue, cardiorespiratory fitness improvements derived from physical activity might enhance benefits. [ABSTRACT FROM AUTHOR]