51. Naringenin derivatives as anti-atherogenic agents
- Author
-
Surk-Sik Moon, Chul-Ho Lee, Chul-Tae Kim, Tae-Sook Jeong, Sangku Lee, Song Hae Bok, Eung-Soo Kim, and Bang Hyun Kim
- Subjects
Naringenin ,Arteriosclerosis ,Clinical Biochemistry ,Flavonoid ,Pharmaceutical Science ,Ether ,Pharmacology ,Biochemistry ,Chemical synthesis ,chemistry.chemical_compound ,Structure-Activity Relationship ,Drug Discovery ,Structure–activity relationship ,Animals ,Molecular Biology ,chemistry.chemical_classification ,Cholesterol ,Organic Chemistry ,food and beverages ,Biological activity ,General Medicine ,Lipids ,chemistry ,Polyphenol ,Anti atherogenic ,Flavanones ,Molecular Medicine ,Diet, Atherogenic ,lipids (amino acids, peptides, and proteins) ,Rabbits - Abstract
Two classes of naringenin derivatives were evaluated for anti-atherogenic activity. Naringenin 7-O-oleic ester (2) and naringenin 7-O-cetyl ether (3) inhibited the formation of aortic atherosclerotic lesions in high cholesterol-fed rabbits.
- Published
- 2003