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71 results on '"Smyth, Emily"'

52. Frequency of skeletal-related events and associated health care resource use and costs in US patients with multiple myeloma

Author

Li, Li, Nelson, David R., Smyth, Emily Nash, Conti, Ilaria, Wooldridge, James E., Bowman, Lee, and Ball, Daniel E.

Abstract

Objective: A potential complication for all new multiple myeloma (MM) patients is the clinical presentation of osteolytic lesions which increase the risk for skeletal-related events (SREs). However, the contribution of SREs to the overall economic impact of MM is unclear. The impact of SREs on health care resource utilization (HCRU) and costs for US patients with MM was analyzed in Truven Health Marketscan® Commercial Claims and Medicare Supplemental Databases.Methods: Adults diagnosed with MM between January 1, 2005 and December 31, 2010 with ≥2 claims ≥30 days apart (first claim=index date) were included. SREs included: hypercalcemia, pathologic fracture, surgery for the prevention and treatment of pathologic fractures or spinal cord compression, and radiation for bone pain. Rates of HCRU (outpatient [OP], inpatient [IP], emergency room [ER], orthopedic consultation [OC], and ancillary) and healthcare costs were compared between MM patients with and without SREs. Inverse propensity weighting was applied to adjust for potential bias.Results: Of 1028 MM patients (mean age 67, standard deviation 13.2), 596 patients with ≥1 SRE and 432 without SREs were assessed. HCRU rates in IP, ER, and ancillary (PPPPLimitations: A broad assessment of pharmacotherapy for the treatment of MM was not an objective of the current study. Bisphosphonate use was evaluated; however, results were descriptively focused on frequency of utilization only and were not included in the broader cost and HCRU analysis.Conclusions: Among US patients with MM, higher SRE frequency was associated with a significant trend of higher HCRU and total healthcare costs in several settings.

Published
2015
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65. A REVIEW OF HEALTH TECHNOLOGY APPRAISALS: CASE STUDIES IN ONCOLOGY.

Author

Shah, Koonal Kirit, Mestre-Ferrandiz, Jorge, Towse, Adrian, and Smyth, Emily Nash

Abstract

Pharmaceutical manufacturers, regulators, patients, providers, and payers all have a shared interest in improving health outcomes for patients with cancer. Each plays an important role in helping to achieve this common goal. Pharmaceutical manufacturers seek to develop new medicines that are supported by robust and clinically meaningful evidence of their safety, efficacy, and effectiveness. Regulators authorize these medicines based on evaluations of their safety and efficacy. Patients and providers together make treatment decisions and desire access to the most effective treatment options. Payers appraise new medicines with the goal of ensuring access to those medicines that constitute efficient uses of healthcare expenditure. Profits generated from the sale of the medicines provide a return to the manufacturer, which helps to drive continued research and development in an effort to improve patient health outcomes and societal well-being. Many payers have initiated health technology assessment (HTA) activities to inform decision making in light of the rising costs of health care. Given the financial constraints imposed as a result of the global economic crisis, HTAs are likely to become increasingly important as payers seek value for money solutions to major health problems. Successful collaboration and aligning incentives across stakeholders is critical to ensuring that patients are able to access the most effective medicines. [ABSTRACT FROM AUTHOR]

Published
2013
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66. CERVICAL CHECK 'PUT LAB COSTS BEFORE QUALITY'.

Author

Ronan Smyth; Emily Webber; Aoife Moore

Abstract

THE CervicalCheck screening programme put the cost of checking smear tests ahead of accuracy, a damning report said yesterday. [ABSTRACT FROM PUBLISHER]

Published
2019

67. Rally claims life of newly-elected councillor.

Author

Ronan Smyth; Emily Webber

Abstract

TRIBUTES have been paid to a Fianna Fáil councillor and threetime rally driving champion who was tragically killed in a crash during the Donegal International Rally yesterday. [ABSTRACT FROM PUBLISHER]

Published
2019

71. LETTERS TO THE EDITORS.

Author

Briggs, S. E., Roth, Louis H., Sandstrom, H. G., O'Brien, William J., Erwin, Beulah, Reynolds, Ella, Rees, Richard, Smyth, Emily B., and Faulkner, Dorothea M.

Subjects
*LETTERS to the editor, *CITIES & towns, *AUTOBIOGRAPHY, *SHORT story (Literary form)
Abstract

Several letters to the editor are presented in response to articles in previous issues including "Cities Series," a story about the life of Ex-Comrade Kirrill Mikhailovich Alexeev in the June 26-July 10, 1948 issue, and "The Mysterious Mona Lisa Smile," by Gerald Kersh in the June 26, 1948 issue.

Published
1948

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