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Numerous geoemydid turtle fossils from the extinct genus Echmatemys have been recovered from the middle Eocene Uinta Formation, Uinta Basin, Utah over the past several decades. Here, we tested whether co-occurring Uintan species Echmatemys callopyge and E. uintensis can be reliably differentiated based on epiplastral morphology, and whether their geospatial distributions overlapped significantly. The geographic spatial and stratigraphic distributions of Uinta Basin E. callopyge and E. uintensis specimens were compared using ArcGIS and analysis of variance (ANOVA). The analysis revealed overlapping geographic distributions of these two species, and no significant differences in stratigraphic dispersal. This finding of extensive geospatial overlap between the two Uintan Echmatemys species highlights the need for accurate taxonomic identification, such as the gular scale morphology validated here. In addition, we sought to address a methodological question regarding the relative efficacy of data complexity in this context. Using epiplastra from three additional Eocene species of Echmatemys, we employed hierarchical analyses of increasing data complexity, from standard linear dimensions to 2D geometric morphometrics to 3D laser scans, to determine the degree to which data complexity contributes to taxonomic assessments within this genus. Uintan species E. callopyge and E. uintensis were found to differ significantly in epiplastral shape as captured by all three categories of data. These findings verify that these two co-occurring species can be differentiated consistently using the shape of the gular scale, and that the use of geometric morphometrics can improve identification of fragmentary specimens. Among the non-Uintan species, dorsal and ventral 2D landmark data reliably differentiated among species, but the linear dimensions were less useful.

OBJECTIVE:The SI gene encodes the sucrase-isomaltase enzyme, a disaccharidase expressed in the intestinal brush border. Hypomorphic SI variants cause recessive congenital sucrase-isomaltase deficiency (CSID) and related gastrointestinal (GI) symptoms. Among children presenting with chronic, idiopathic loose stools, we assessed the prevalence of CSID-associated SI variants relative to the general population and the relative GI symptom burden associated with SI genotype within the study population. METHODS:A prospective study conducted at 18 centers enrolled 308 non-Hispanic white children ≤18 years old who were experiencing chronic, idiopathic, loose stools at least once per week for >4 weeks. Data on demographics, GI symptoms, and genotyping for 37 SI hypomorphic variants were collected. Race/ethnicity-matched SI data from the Exome Aggregation Consortium (ExAC) database was used as the general population reference. RESULTS:Compared with the general population, the cumulative prevalence of hypomorphic SI variants was significantly higher in the study population (4.5% vs. 1.3%, P < .01; OR = 3.5 [95% CI: 6.1, 2.0]). Within the study population, children with a hypomorphic SI variant had a more severe GI symptom burden than those without, including: more frequent episodes of loose stools (P < .01), higher overall stool frequency (P < .01), looser stool form (P = .01) and increased flatulence (P = .02). CONCLUSION:Non-Hispanic white children with chronic idiopathic loose stools have a higher prevalence of CSID-associated hypomorphic SI variants than the general population. The GI symptom burden was greater among the study subjects with a hypomorphic SI variant than those without hypomorphic SI variants.

ObjectiveCaregivers for patients undergoing hematopoietic cell transplantation (HCT) are susceptible to significant psychosocial distress. This cross-sectional study aimed to describe psychosocial support services offered and used by caregivers of pediatric primary immune deficiency (PID) during HCT at 35 hospitals across North America.MethodCaregivers of pediatric patients with PID were recruited by e-mail to participate in an anonymous 140-question survey instrument between April and May 2016 (N = 171).ResultOf those meeting inclusion criteria (53%), family counseling services were only offered to fewer than half of caregivers (42%). Of the survey participants not offered counseling services, the majority desired family counseling (70%) and sibling counseling (73%). That said, when offered counseling, utilization rates were low, with 22% of caregivers using family counseling and none using sibling counseling.Significance of resultsThese results indicate the need to offer and tailor counseling services for families throughout the HCT process. Further research should focus on reducing barriers to utilization of counseling services such as offering bedside counseling services, online modalities, and/or financial assistance.

BackgroundCaregivers of children with primary immunodeficiency disorders (PIDs) experience significant psychological distress during their child's hematopoietic cell transplantation (HCT) process.ObjectivesThis study aims to understand caregiver challenges and identify areas for health care system-level improvements to enhance caregiver well-being.MethodsIn this mixed-methods study caregivers of children with PIDs were contacted in August to November 2017 through online and electronic mailing lists of rare disease consortiums and foundations. Caregivers were invited to participate in an online survey assessing sociodemographic variables, the child's medical characteristics, psychosocial support use, and the World Health Organization-5 Well-Being Index. Open-ended questions about health care system improvements were included. Descriptive statistics and linear multivariate regression analyses were conducted. A modified content analysis method was used to code responses and identify emergent themes.ResultsAmong the 80 caregiver respondents, caregivers had a median age of 34 years (range, 23-62 years) and were predominantly female, white, and married with male children given a diagnosis of severe combined immune deficiency. In the adjusted regression model lower caregiver well-being was significantly associated with lower household income and medical complications. Challenges during HCT include maintaining relationships with partners and the child's healthy sibling or siblings, managing self-care, and coping with feelings of uncertainty. Caregivers suggested several organizational-level solutions to enhance psychosocial support, including respite services, online connections to other PID caregivers, and bedside mental health services.ConclusionsCertain high-risk subpopulations of caregivers might need more targeted psychosocial support to reduce the long-term effect of the HCT experience on their well-being. Caregivers suggested several organizational-level solutions for provision of this support.

Analysis of CCAPS-34 scores on a large (n = 4,852) university counseling center student sample supported internal consistency ([alpha] = 0.803-0.896), one-month test-retest reliability (r[subscript tt] = 0.706-0.829), convergent and divergent validity, and good model fit. Measurement invariance of scores for all categories of race and student status was supported.

This study explored internal consistency ([alpha] = 0.834), test-retest (r[subscript tt] = 0.911), convergent validity, and internal structural validity of the Alcohol Use Disorders Identification Test (AUDIT) on a large university student sample. The 2-factor model fit the data best and measurement invariance was demonstrated for Latinx, but not undergraduate/graduate levels.

The uptake of green infrastructure is challenged by a lack of access to financing. Studies have investigated individuals' economic valuation of green infrastructure but understanding public perceptions of a range of potential funding mechanisms is a fundamental step in developing funding measures. Using data collected from a sample of residents in the Oxford–Cambridge Arc, England, this study addresses a gap in our understanding of public perceptions of green infrastructure funding by investigating support for several funding mechanisms, and the extent to which support is associated with attitudinal, contextual and personal capability variables. Results indicate that respondents prefer the funding of small and large-scale infrastructure to be covered by developers, with most opposition being levelled at those involving additional financial obligations from citizens. Altruistic-biospheric values, pro-environmental behaviour and trust in the government significantly affected support. These findings provide valuable insight to policymakers attempting to introduce sustainable green infrastructure funding streams. [ABSTRACT FROM AUTHOR]

Translanguaging claims to advance social justice as a transformative pedagogy. This paper analyses a tension which developed over the life span of a European research project which aimed to improve the educational experience for Eastern European Roma pupils through teachers' employment of a translanguaging pedagogy. Roma are ethnically and linguistically heterogeneous, but as a minority group face continued racism, whilst Roma pupils face educational exclusion. The voices of Roma parents, pupils and activists and academics alerted us to potential threats in utilising translanguaging as a political act for transformation in education. They revealed a central tension between recognition of linguistic pluralism for emancipation at school level (with possibilities for policy level changes at local or national levels) and unifying endeavours for collective action towards equality and human rights at a (trans)national level. To understand this tension we reframed it in light of the postmodernist positioning of translanguaging, and critiques of the de-politicizing tendencies of postmodernism. In proposing a way forward for research and pedagogy, we carve a path between pluralism and collectivism by placing translanguaging pedagogy and associated research into Nancy Fraser's integrative model of recognition and redistribution for transformation.

This article is a case study of one Community-University Research and Action Partnership (CURAP) focused on soil lead, urban gardening, and environmental justice in Sacramento, California. We argue that creating and sustaining CURAPs requires a process of weaving together diverse strands of knowledge, resources, and lines of accountability that connect all parties involved. Like the physical process of weaving fabric, weaving CURAPs involve creative and collaborative uses and responses to tension between all elements of a partnership. This is especially true in long-term partnerships intended to address systemic environmental injustices. This case highlights the power relationships and challenges associated with such partnerships and presents several lessons to enrich the scholarship and practices of action research.