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1,365 results on '"Slaughter, Mark S."'

58. Prospective Multicenter Study of Myocardial Recovery Using Left Ventricular Assist Devices (RESTAGE-HF [Remission from Stage D Heart Failure]): Medium-Term and Primary End Point Results

Author

Birks, Emma J., Drakos, Stavros G., Patel, Snehal R., Lowes, Brian D., Selzman, Craig H., Starling, Randall C., Trivedi, Jaimin, Slaughter, Mark S., Alturi, Pavin, Goldstein, Daniel, Maybaum, Simon, Um, John Y., Margulies, Kenneth B., Stehlik, Josef, Cunningham, Christopher, Farrar, David J., and Rame, Jesus E.

Published
2020
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67. Machine Learning Identification Of Transcriptomics And Clinical Characteristics Associated With Myocardial Recovery In Heart Failure Patients Undergoing Mechanical Circulatory Support

Author

Kyriakopoulos, Christos P, primary, Visker, Joseph R, additional, Brintz, Ben J, additional, Taleb, Iosif, additional, Badolia, Rachit, additional, Haaland, Benjamin, additional, Shankar, Thirupura S, additional, Ling, Jing, additional, Hamouche, Rana, additional, Tseliou, Eleni, additional, Sideris, Konstantinos, additional, Scott, Monte, additional, Krauspe, Ethan, additional, Navankasattusas, Sutip, additional, Wever-Pinzon, Omar, additional, Hanff, Thomas C, additional, Bailey, Stephen, additional, Koenig, Steven, additional, Alharethi, Rami, additional, Greene, Tom H, additional, Selzman, Craig H, additional, Slaughter, Mark S, additional, Kanwar, Manreet, additional, Shah, Palak, additional, and Drakos, Stavros G, additional

Published
2023
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71. The HVAD Left Ventricular Assist Device: Risk Factors for Neurological Events and Risk Mitigation Strategies

Author

Teuteberg, Jeffrey J., Slaughter, Mark S., Rogers, Joseph G., McGee, Edwin C., Pagani, Francis D., Gordon, Robert, Rame, Eduardo, Acker, Michael, Kormos, Robert L., Salerno, Christopher, Schleeter, Thomas P., Goldstein, Daniel J., Shin, Julia, Starling, Randall C., Wozniak, Thomas, Malik, Adnan S., Silvestry, Scott, Ewald, Gregory A., Jorde, Ulrich P., Naka, Yoshifumi, Birks, Emma, Najarian, Kevin B., Hathaway, David R., and Aaronson, Keith D.

Published
2015
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85. Amiodarone Use and All‐Cause Mortality in Patients With a Continuous‐Flow Left Ventricular Assist Device

Author

Gopinathannair, Rakesh, primary, Pothineni, Naga Venkata K., additional, Trivedi, Jaimin R., additional, Roukoz, Henri, additional, Cowger, Jennifer, additional, Ahmed, Mustafa M., additional, Bhan, Adarsh, additional, K. Ravichandran, Ashwin, additional, Bhat, Geetha, additional, Al Ahmad, Amin, additional, Natale, Andrea, additional, Di Biase, Luigi, additional, Slaughter, Mark S., additional, and Lakkireddy, Dhanunjaya, additional

Published
2022
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86. HVAD to HeartMate 3 Left Ventricular Assist Device Exchange: Best Practices Recommendations

Author

Salerno, Christopher T., primary, Hayward, Christopher, additional, Hall, Shelley, additional, Goldstein, Daniel, additional, Saeed, Diyar, additional, Schmitto, Jan, additional, Kaczorowski, David, additional, Molina, Ezequiel, additional, Zimpfer, Daniel, additional, Tsui, Steven, additional, Soltesz, Edward, additional, Pham, Duc Thin, additional, Mokadam, Nahush A., additional, Kilic, Arman, additional, Davis, Erin, additional, Feller, Erika, additional, Lorts, Angela, additional, Silvestry, Scott, additional, Slaughter, Mark S., additional, Potapov, Evgenij, additional, Atluri, Pavan, additional, Cowger, Jennifer, additional, Pagani, Francis D., additional, and Salerno, Christopher T., additional

Published
2022
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96. Intraoperative Fraction of Inspired Oxygen and Lung Injury in Coronary Artery Bypass Grafting: Study Protocol for a Randomised Controlled Trial.

Author

Kaicheng Song, Sheng Wang, Jiange Han, Luyang Jiang, Junmei Xu, Akca, Ozan, Adkins, Kandis, Koenig, Heidi M., Slaughter, Mark S., Clifford, Sean P., Yuguang Huang, and Jiapeng Huang

Subjects
LUNG injuries, CORONARY artery bypass, RESPIRATORY distress syndrome, RANDOMIZED controlled trials, PERIOPERATIVE care
Abstract

Objective: Postoperative pulmonary complications are a series of disorders that can contribute to respiratory distress and prolonged mechanical ventilation postoperatively. We hypothesise that a liberal oxygenation strategy during cardiac surgery leads to a higher incidence of postoperative pulmonary complications than a restrictive oxygenation strategy. Methods: This study is a prospective, observer-blinded, centrally randomised and controlled, international multicentre clinical trial. Results: After obtaining a written informed consent, 200 adult patients undergoing coronary artery bypass grafting will be enrolled and randomised to receive either restrictive or liberal oxygenation perioperatively. The liberal oxygenation group will receive 1.0 fraction of inspired oxygen throughout the intraoperative period, including during cardiopulmonary bypass. The restrictive oxygenation group will receive the lowest fraction of inspired oxygen required to maintain arterial partial pressure of oxygen between 100 and 150 mmHg during cardiopulmonary bypass and a pulse oximetry reading of 95% or greater intraoperatively, but no less than 0.3 and not higher than 0.80 (other than induction and when the oxygenation goals cannot be reached). When patients are transferred to the intensive care unit, all patients will receive an initial fraction of inspired oxygen of 0.5, and then fraction of inspired oxygen will be titrated to maintain a pulse oximetry reading of 95% or greater until extubation. The lowest postoperative arterial partial pressure of oxygen/fraction of inspired oxygen within 48 hours of intensive care unit admission will be the primary outcome. Postoperative pulmonary complications, length of mechanical ventilation, intensive care unit stay, hospital stay, and 7-day mortality after cardiac surgery will be analysed as secondary outcomes. Conclusion: This is one of the first randomised controlled observer-blinded trials that prospectively evaluates the influence of higher inspired oxygen fractions on early postoperative respiratory and oxygenation outcomes in cardiac surgery patients using cardiopulmonary bypass. [ABSTRACT FROM AUTHOR]

Published
2023
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97. Impact of 2016 UNOS pediatric heart allocation policy changes on VAD utilization, waitlist, and post‐transplant survival outcomes in children with CHD versus Non‐CHD.

Author

Das, Bibhuti B., Blackshear, Chad T., Lirette, Seth T., Slaughter, Mark S., Ghaleb, Stephanie, Moskowitz, William, Ghanamah, Mohammad, and Burch, Phillip T.

Subjects
SURVIVAL rate, TREATMENT effectiveness, HEART assist devices, CONGENITAL heart disease
Abstract

Aims: We analyzed the impact of the revised pediatric heart allocation policy on types of ventricular assist device (VAD) utilization, and waitlist (WL) and post‐heart transplant (HT) survival outcomes in congenital heart disease (CHD) versus non‐CHD patients before (Era‐1) and after (Era‐2) pediatric heart allocation policy implementation. Methods: We retrospectively reviewed the UNOS database from December 16, 2011, through March 31, 2021, for patients < 18 years old and listed for primary HT. We compared the differences observed between Era‐1 and Era‐2. Results: 5551 patients were listed for HT, of whom 2447(44%) were in Era‐1 and 3104(56%) were in Era‐2. CHD patients were listed as status 1A unchanged, but the number of patients listed as status 1B decreased in Era‐2, whereas the number of non‐CHD patients listed as status 1A decreased, but status 1B increased. In Era‐2 compared to Era‐1, both temporary (1% to 4%, p <.001) and durable VAD (13.6% to 17.8%, p <.001) utilization increased, and the transplantation rate per 100‐patient years increased in both groups. The median WL period for CHD patients increased marginally from 70 to 71 days (p =.06), whereas for non‐CHD patients it decreased from 61 to 54 days (p <.001). Adjusted 90‐day WL survival increased from 84% to 88%, p =.016 in CHD, but there was no significant change in non‐CHD patients (p =.57). There was no significant difference in 1‐year post‐HT survival in CHD and non‐CHD patients between Era‐1 and Era‐2. Conclusions: In summary, after the revised heart allocation policy implementation, temporary and durable VAD support increased, HT rate increased, waitlist duration marginally increased in the CHD cohort and decreased in the non‐CHD cohort, and 90‐day WL survival probability improved in children with CHD without significant change in 1‐year post‐HT outcomes. Future studies are needed to identify changes to the policy that may further improve the listing criteria to improve WL duration and post‐HT survival. [ABSTRACT FROM AUTHOR]

Published
2023
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99. Interrelationship of preoperative anemia, intraoperative anemia, and red blood cell transfusion as potentially modifiable risk factors for acute kidney injury in cardiac surgery: a historical multicentre cohort study

Author

Karkouti, Keyvan, Grocott, Hilary P., Hall, Richard, Jessen, Michael E., Kruger, Cornelis, Lerner, Adam B., MacAdams, Charles, Mazer, C. David, de Medicis, Étienne, Myles, Paul, Ralley, Fiona, Rheault, Michel R., Rochon, Antoine, Slaughter, Mark S., Sternlicht, Andrew, Syed, Summer, and Waters, Terrence

Published
2015
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