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498 results on '"Siu G"'

51. An assessment of the readiness for introduction of the HPV vaccine in Uganda

Author

Katahoire, RA, Jitta, J, Kivumbi, G, Murokora, D, Arube, WJ, Siu, G, Arinaitwe, L, Bingham, A, Mugisha, E, Tsu, V, and LaMontagne, DS

Subjects
Human papillomavirus, vaccine, formative research, cervical cancer, Uganda
Abstract

Formative research assessing human papillomavirus (HPV) vaccine readiness in Uganda was conducted in 2007. The objective was to generate evidence for government decision-making and operationalplanning for HPV vaccine introduction. Qualitative research methods with children, parents, teachers, community leaders, health workers, technical experts and political leaders were used to captureunderstanding of socio-cultural, health system and policy environments. We found low levels of knowledge about cervical cancer and HPV. Vaccination and its benefits were well-understood;respondents were positive about HPV vaccination. Health systems were deemed adequate for HPV vaccine delivery. Schools were identifie as a vaccination venue, given high attendance by girls aged10-12 years. Communication and advocacy strategies to foster acceptance should provide information on cervical cancer, HPV vaccine safety, and side effects. Policymakers requested further detail on costs.Introduction of HPV vaccine could be integrated into existing reproductive health and immunization policies (Afr J Reprod Health 2008; 12[3]:159-172).

Published
2010

53. [Clinical, biochemical and hepatic histological findings in overweight and obese Peruvian adults: first national prospective study]

Author

Martín, Tagle A, Luis, Poggi M, Natalia, Ferrari G, Hugo, Siu G, Melina, Aguinaga, Eduardo, Luna C, and Yolanda, Scavino L

Subjects
Adult, Male, Young Adult, Liver Diseases, Peru, Prevalence, Humans, Female, Obesity, Prospective Studies, Middle Aged, Overweight, Aged
Abstract

We conducted a prospective, descriptive study in the Clinica Anglo Americana, a prívate institution taking care of patients from a medium-high socioeconomic level in Lima. The goal of the study was to determine the frequency of histologic findings in liver biopsies performed by laparoscopy or percutaneously in patients with overweight (body mass index25 kg/m2) or obesity (body mass index30 kg/m2), and to evaluate the correlation with antropometric variables such as BMI, waist circumference, history of diabetes or hyperlypidemia, and biochemical variables like glycemia, lipid profile, aminotransferases and AST/ALT ratio. Between the years 2001 and 2006 50 patients were biopsied, 29 with overweight and 21 with obesity. Eighteen had simple steatosis and 22 had Non-alcoholic steatohepatitis (NASH) (44%), so 40 patients (80%) had some form of fatty liver. Five patients (10%) had cirrhosis confirmed by biopsy, and in all of them the finding of cirrhosis was completely incidental. Sixty four percent of patients with NASH were obese, like the 5 cirrhotics in our series. Herein we illustrate that in a relatively small sample of patients with obesity and overweight like ours, we found all the forms of the liver steatosis spectrum, from simple steatosis to cirrhosis, with a high frequency of NASH.

Published
2009

54. Horseshoe crab genomes reveal the evolution of genes and microRNAs after three rounds of whole genome duplication

Author

Wenyan Nong, Zhe Qu, Yiqian Li, Tom Barton-Owen, Annette Y. P. Wong, Ho Yin Yip, Hoi Ting Lee, Satya Narayana, Tobias Baril, Thomas Swale, Jianquan Cao, Ting Fung Chan, Hoi Shan Kwan, Sai Ming Ngai, Gianni Panagiotou, Pei-Yuan Qian, Jian-Wen Qiu, Kevin Y. Yip, Noraznawati Ismail, Siddhartha Pati, Akbar John, Stephen S. Tobe, William G. Bendena, Siu Gin Cheung, Alexander Hayward, and Jerome H. L. Hui

Subjects
Biology (General), QH301-705.5
Abstract

Wenyan Nong, Zhe Qu, Yiqian Li, Tom Barton-Owen, Annette Wong and colleagues provide genomes and small RNA transcriptomes for the mangrove horseshoe crab and the tri-spine horseshoe crab. They show that horseshoe crabs have undergone three rounds of whole genome duplication and shed light on how gene families and microRNAS evolved following this genome duplication event.

Published
2021
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55. Quality assessment and improvement in optometric practices

Author

Lyman C, Norden, Mary S, Loshin, Carol L, Brown, Jeffrey T, Keller, Carl F, Gruning, Robert P, Aitken, Allen J, Blume, James D, Colgain, Sarah C, Gordon, William W, Hately, James R, Hoffman, Susan R, Johnson, David S, Loshin, Zoe, Lyle, Francis L, McVeigh, Lesley L, Walls, Diana L, Watkins, Roger J, Wilson, and Siu G, Wong

Subjects
Quality Assurance, Health Care, Humans, Professional Practice, Optometry
Published
2002

58. Stable Isotope Tracer Addition Reveals the Trophic Status of Benthic Infauna at an Intertidal Area Adjacent to a Seagrass Bed

Author

Wenzhe Xu, Yongxin Dang, Siu Gin Cheung, Zhinan Zhang, Jun Sun, Ankang Teng, and Paul K. S. Shin

Subjects
stable isotope, trophic study, meiofauna, nematodes, polychaetes, isotope tracer addition, Science, General. Including nature conservation, geographical distribution, QH1-199.5
Abstract

Stable isotope tracer addition can enhance the isotopic differences of primary producers for a wider food-web resolution than the use of natural abundance stable isotopes (NASIs) alone, particularly in ecosystems where primary producers have similar NASI values. To investigate the food sources and the trophic status of benthic infauna in an intertidal area near a Halophila minor seagrass bed within inner Tai Tam Bay, Hong Kong, China, a 15N addition experiment was conducted, and the results were compared with those from NASI data. Only benthic microalgae (BMA) were labeled by applying 15N-enriched NH4Cl to the sediment daily for the first 7 days during a 21-day study. In contrast to the NASI results, Bayesian mixing models based on the isotope tracer experiment suggested a larger dietary contribution of BMA for nematode Daptonema sp. and copepods, whereas a higher reliance on phytoplankton and seagrass detritus was noted for polychaete Neanthes sp. However, both NASI and isotope tracer addition demonstrated that seagrass detritus was a major food source for nematode Spilophorella sp. The present isotope tracer experiment also revealed a contrasting result of the relatively lower contribution of meiofauna in the diets of carnivores/omnivores as compared to the results of NASIs. This finding suggested that the isotope values in these consumers may have not reached an equilibrium with the added isotope in the study period. Thus, there is a need for applying NASI coupled with isotope tracer addition in the investigation of ecosystems in which primary producers have similar isotope values, especially in ecosystems with lower tissue turnover rates, in order for a more accurate determination of dietary contribution and trophic status of consumers in the food-web study.

Published
2021
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60. Monoclonal antibodies to B and T lymphocyte attenuator (BTLA) have no effect on in vitro B cell proliferation and act to inhibit in vitro T cell proliferation when presented in a cis, but not trans, format relative to the activating stimulus

Author

Zhang, M, primary, Howard, K, additional, Winters, A, additional, Steavenson, S, additional, Anderson, S, additional, Smelt, S, additional, Doellgast, G, additional, Sheelo, C, additional, Stevens, J, additional, Kim, H, additional, Hamburger, A, additional, Sein, A, additional, Caughey, D J, additional, Lee, F, additional, Hsu, H, additional, Siu, G, additional, and Byrne, F R, additional

Published
2010
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71. Performance of the new automated Abbott RealTi me MTB assay for rapid detection of Mycobacterium tuberculosis complex in respiratory specimens.

Author

Chen, J., She, K., Kwong, T.-C., Wong, O.-Y., Siu, G., Leung, C.-C., Chang, K.-C., Tam, C.-M., Ho, P.-L., Cheng, V., Yuen, K.-Y., and Yam, W.-C.

Subjects
MYCOBACTERIUM tuberculosis, POLYMERASE chain reaction, MICROBIOLOGICAL assay, DIAGNOSTIC specimens, MYCOBACTERIUM, PATHOLOGICAL laboratories, DIAGNOSIS
Abstract

The automated high-throughput Abbott RealTi me MTB real-time PCR assay has been recently launched for Mycobacterium tuberculosis complex (MTBC) clinical diagnosis. This study would like to evaluate its performance. We first compared its diagnostic performance with the Roche Cobas TaqMan MTB assay on 214 clinical respiratory specimens. Prospective analysis of a total 520 specimens was then performed to further evaluate the Abbott assay. The Abbott assay showed a lower limit of detection at 22.5 AFB/ml, which was more sensitive than the Cobas assay (167.5 AFB/ml). The two assays demonstrated a significant difference in diagnostic performance (McNemar's test; P = 0.0034), in which the Abbott assay presented significantly higher area under curve (AUC) than the Cobas assay (1.000 vs 0.880; P = 0.0002). The Abbott assay demonstrated extremely low PCR inhibition on clinical respiratory specimens. The automated Abbott assay required only very short manual handling time (0.5 h), which could help to improve the laboratory management. In the prospective analysis, the overall estimates for sensitivity and specificity of the Abbott assay were both 100 % among smear-positive specimens, whereas the smear-negative specimens were 96.7 and 96.1 %, respectively. No cross-reactivity with non-tuberculosis mycobacterial species was observed. The superiority in sensitivity of the Abbott assay for detecting MTBC in smear-negative specimens could further minimize the risk in MTBC false-negative detection. The new Abbott RealTi me MTB assay has good diagnostic performance which can be a useful diagnostic tool for rapid MTBC detection in clinical laboratories. [ABSTRACT FROM AUTHOR]

Published
2015
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