3,741 results on '"Siciliano P"'
Search Results
52. A case of early disease rebound after fingolimod discontinuation in a patient with multiple sclerosis and SARS-CoV-2 infection
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Giovannini, Beatrice, Panelli, Deborah, Bianchi, Francesca, Siciliano, Gabriele, and Pasquali, Livia
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- 2024
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53. Necrophagy and Marine Megafauna Predation By Sharks in a Hotspot in the Southwest Atlantic Ocean
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da Silva, Rian Pereira, Barbosa-Filho, Márcio Luiz Vargas, Siciliano, Salvatore, Hauser-Davis, Rachel Ann, Souza, Gabriel Barros Gonçalves, Seminara, Cecilia Inés, Pavanelli, Larissa, and Ikeda, Joana Midori Penalva
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- 2024
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54. Metal–organic framework application in wastewater treatment: a review
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Coppola, Gerardo, Bhattacharyya, Saurav, Pugliese, Valerio, Algieri, Catia, Petrosino, Francesco, Siciliano, Sarah, and Calabro, Vincenza
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- 2024
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55. Maternal Mental Health in Refugees and Migrants: a Comprehensive Systematic Review
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Almeida, Lígia Moreira, Moutinho, Ana Raquel, Siciliano, Florencia, Leite, Jorge, and Caldas, José Peixoto
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- 2024
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56. Modeling tuberous sclerosis complex with human induced pluripotent stem cells
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Niu, Weibo, Siciliano, Benjamin, and Wen, Zhexing
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- 2024
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57. Objective assessment of physical activity and sedentary time of older adults using ambient and wearable sensor technologies
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Caroppo, Andrea, Leone, Alessandro, and Siciliano, Pietro
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- 2024
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58. Neurogenic orthostatic hypotension in Parkinson’s disease: is there a role for locus coeruleus magnetic resonance imaging?
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Palermo, Giovanni, Galgani, Alessandro, Bellini, Gabriele, Lombardo, Francesco, Martini, Nicola, Morganti, Riccardo, Paoli, Davide, De Cori, Sara, Frijia, Francesca, Siciliano, Gabriele, Ceravolo, Roberto, and Giorgi, Filippo Sean
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- 2024
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59. Comparing plasma and skin imprint metabolic profiles in COVID-19 diagnosis and severity assessment
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Delafiori, Jeany, Siciliano, Rinaldo Focaccia, de Oliveira, Arthur Noin, Nicolau, José Carlos, Sales, Geovana Manzan, Dalçóquio, Talia Falcão, Busanello, Estela Natacha Brandt, Eguti, Adriana, de Oliveira, Diogo Noin, Bertolin, Adriadne Justi, dos Santos, Luiz Augusto, Salsoso, Rocío, Marcondes-Braga, Fabiana G., Durán, Nelson, Júnior, Maurício Wesley Perroud, Sabino, Ester Cerdeira, Reis, Leonardo Oliveira, Fávaro, Wagner José, and Catharino, Rodrigo Ramos
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- 2024
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60. Intrinsic brain functional connectivity predicts treatment-related motor complications in early Parkinson’s disease patients
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De Micco, Rosa, Di Nardo, Federica, Siciliano, Mattia, Silvestro, Marcello, Russo, Antonio, Cirillo, Mario, Tedeschi, Gioacchino, Esposito, Fabrizio, and Tessitore, Alessandro
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- 2024
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61. Identities and derived lengths of finitary incidence algebras and their group of units
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Khrypchenko, Mykola and Siciliano, Salvatore
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Mathematics - Rings and Algebras ,Mathematics - Group Theory ,16S50, 16R10, 17B60 - Abstract
Let $FI(X,K)$ be the finitary incidence algebra of a poset $X$ over a field $K$. In this short note we establish when $FI(X,K)$ satisfies a polynomial identity and when its group of units $\mathcal{U}(FI(X,K))$ satisfies a group identity. The Lie derived length of $FI(X,K)$ and the derived length of $\mathcal{U}(FI(X,K))$ are also determined., Comment: Revised according to referee's comments
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- 2023
62. Wigner Gaussian dynamics: simulating the anharmonic and quantum ionic motion
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Siciliano, Antonio, Monacelli, Lorenzo, Caldarelli, Giovanni, and Mauri, Francesco
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Condensed Matter - Materials Science - Abstract
The atomic motion controls important features of materials, such as thermal transport, phase transitions, and vibrational spectra. However, the simulation of ionic dynamics is exceptionally challenging when quantum fluctuations are relevant (e.g., at low temperatures or with light atoms) and the energy landscape is anharmonic. In this work, we formulate the Time-Dependent Self-Consistent Harmonic Approximation (TDSCHA) in the Wigner framework, paving the way for the efficient computation of the nuclear motion in systems with sizable quantum and thermal anharmonic fluctuations. Besides the improved numerical efficiency, the Wigner formalism unveils the classical limit of TDSCHA and provides a link with the many-body perturbation theory of Feynman diagrams. We further extend the method to account for the non-linear couplings between phonons and photons, responsible, e.g., for a nonvanishing Raman signal in high-symmetry Raman inactive crystals, firstly discussed by Rasetti and Fermi. We benchmark the method in phase III of high-pressure hydrogen ab initio. The nonlinear photon-phonon coupling reshapes the IR spectra and explains the high-frequency shoulder of the H2 vibron observed in experiments. The Wigner TDSCHA is computationally cheap and derived from first principles: it is unbiased by assumptions on the phonon-phonon and phonon-photon scattering and does not depend on empirical parameters. Therefore, the method can be adopted in unsupervised high-throughput calculations., Comment: 36 pages, 9 figures, 1 table
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- 2023
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63. Eggs in finite projective spaces and unitals in translation planes
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Monzillo, Giusy, Penttila, Tim, and Siciliano, Alessandro
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Mathematics - Combinatorics ,51E20, 51E21 - Abstract
Inspired by the connection between ovoids and unitals arising from the Buekenhout construction in the Andr\'e/Bruck-Bose representation of translation planes of dimension at most two over their kernel, and since eggs of PG(4m-1,q), m>=1, are a generalization of ovoids, we explore the relation between eggs and unitals in translation planes of higher dimension over their kernel. By investigating such a relationship, we construct a unital in the Dickson semifield plane of order 3^{10}, which is represented in PG(20,3) by a cone whose base is a set of points constructed from the dual of the Penttila-Williams egg in PG(19,3). This unital is not polar; so, up to the knowledge of the authors, it seems to be a new unital in such a plane.
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- 2023
64. Obesity as a Confounding Factor in the Diagnosis of Wilson’s Disease: Case Report of Two Siblings with the Same Genotype but Different Clinical Courses
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Emanuele Bracciamà, Annamaria Sapuppo, Laura Rapisarda, Enrico Siciliano, Anna Caciotti, Amelia Morrone, Martino Ruggieri, Giuseppina Cantarella, Renato Bernardini, and Gaetano Bertino
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Wilson’s disease ,ATB7B ,obesity ,steatotic liver disease ,Biology (General) ,QH301-705.5 - Abstract
Wilson’s disease (WD) is a biallelic disease-causing variant in the ATP7B gene on chromosome 13q14.3 that results in copper accumulation in many organs, particularly the liver and brain. The phenotypic spectrum is wide and symptoms at onset can be heterogeneous. We describe two Sicilian siblings, a young man and his elder sister, both compound heterozygous for the variants c.1286-2A>G and c.2668G>A (p.Val890Met) in the ATB7B gene. The male patient presented with liver cirrhosis, which quickly progressed to end-stage liver disease (Child–Pugh score = C10), while his sister had moderate steatotic liver disease (SLD). Our findings highlight that SLD may not always be related to obesity in overweight patients, especially when there are other potential risk factors such as a family history of chronic liver disease, or the persistence of high transaminase despite the adoption of adequate dietary and pharmacological intervention. Screening for conditions such as WD could identify patients at risk of developing SLD and avoid delays in diagnosis. Phenotypic variability in WD is considerable; therefore, further studies are needed to identify which WD patients have a greater risk of developing SLD and determine factors that can predict the severity of the disease.
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- 2024
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65. Time-course of oral toxicity to contaminated groundwater in male Sprague Dawley rats
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Bright Boamah, Steven Siciliano, Natacha Hogan, Markus Hecker, Mark Hanson, Patrick Campbell, Rachel Peters, Ahmad N. Al-Dissi, and Lynn Weber
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Complex mixture ,Target organ ,Time course ,Effects directed toxicity testing ,Toxicology. Poisons ,RA1190-1270 - Abstract
Assessing toxicity of complex mixtures of contaminants from industrial sites with historic and ongoing contamination remains a challenge for risk assessors. Groundwater from a pesticide packaging site in Canada containing a complex mixture of known and unknown contaminants was examined in male rats to determine the target organ toxicity. This study determined the time-course of toxicity (7, 14, 28, and 60 days) following ad libitum oral exposure to 0.05% v/v contaminated groundwater compared to tap water (control) in male Sprague Dawley rats (n=5 /group/time). Exposure to groundwater resulted in inflammation, indicated by a statistically significant increase in plasma lymphocyte and neutrophil counts on days 7 and 60, respectively, but a reduction in the plasma alpha 2 macroglobulin levels by day 60. Gonadotoxicity was indicated by a reduced Johnsen score (grading spermatogenesis) in all exposed groups at all time points, while seminiferous epithelial height was reduced on days 7, 14, and 28 compared to controls. Plasma testosterone was reduced in exposed groups on days 7 and 28, accompanied by elevated testicular lipid peroxidation at all time points compared to control. In contrast, lipid peroxidation in the lungs from exposed rats was elevated on days 7, 14, and 28. Plasma symmetric dimethylarginine was elevated on day 14 in the exposed group indicating renal impairment. Taken together, these results indicate that testes, kidney, immune and lung are target organs for the contaminated groundwater from this industrial site. The current study highlights the challenge in hazard assessment for complex mixtures and highlights the need for effects-directed analysis and the continued, albeit limited, use of animal models in toxicity testing.
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- 2024
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66. Evidence of dynamic ferrite transformation during thermomechanical simulation of an X70 microalloyed steel above Ae3 temperature
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Maria Veronica Goncalves Rodrigues, Fulvio Siciliano, Clodualdo Aranas, Marcos da Silva Lima, Rodrigo de Carvalho Paes Loureiro, Gedeon Silva Reis, Eden Santos Silva, Pablo Bruno Paiva Leão, João Carlos Ferreira, Hamilton Ferreira Gomes de Abreu, and Samuel Filgueiras Rodrigues
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Dynamic transformation ,In-situ X-ray diffraction ,Strain-induced ferrite ,EBSD ,Texture ,Mining engineering. Metallurgy ,TN1-997 - Abstract
It is known that dynamic transformation can occur in the austenite field above the Ae3 temperature in a rapidly displacive way and after diffusionally under stress. This phenomenon influences industrial thermomechanical processes by changing the expected applied loads during forging or rolling. In this investigation, laboratory-scale physical simulation of tensile test in a customized Gleeble thermomechanical simulator system equipped with a synchrotron light X-ray beam (12 keV) was carried out on a linepipe steel at 50 °C above the Ae3. The obtained stress-strain curves indicate that dynamic transformation took place during deformation. The X-ray diffraction patterns confirmed the formation of ferrite inside the austenite field during strain. The results confirm the direct evidence of the onset of ferrite formation due to the applied strain and its increase in volume fraction as the deformation continues. The main ferrite-phase peaks detected by the in-situ X-ray diffraction were the ones related to the (110) and (221) planes. Both peaks increased their intensity with the increasing strain, leading to a decrease in the gamma-phase peak intensities of the (111) and (220) planes. The total volume fraction of all ferrite peaks increased to approximately 50% when the strain reached a maximum value, while the fraction of all austenite peaks decreased proportionally. Microscopic measurements of the presented phases have shown excellent agreement with the results obtained from direct X-ray diffraction results. A comprehensive understanding of the dynamic transformation phenomenon mechanism is important to the industry sector in designing improved manufacturing parameters for products with good quality.
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- 2024
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67. APLICAÇÃO DA TÉCNICA DE FOTOIDENTIFICAÇÃO DO BOTO-CINZA, Sotalia fluviatilis, (Cetacea, Delphinidae) DA BAÍA DE SEPETIBA.
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SHEILA MARINO SIMÃO, JOSÉ LUÍS A. PIZZORNO, VANESSA N. PERRY, and SALVATORE SICILIANO
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Fotoidentificação ,Cetáceos ,Sotalia fluviatilis ,Baía de Sepetiba. ,Forestry ,SD1-669.5 - Abstract
RESUMO O catálogo de fotoidentificação da população de boto-cinza, Sotalia fluviatilis, da Baía de Sepetiba vem sendo formado desde 1994. São apresentados os dados preliminares do período entre abril de 1994 a junho de 1998, os quais indicam haver fidelidade ao habitat e algum grau de associação entre indivíduos. São também apresentados os diversos problemas de campo que levam a baixos índices de aproveitamento de fotos. O catálogo de fotoidentificação vem gerando informações que subsidiarão futuros estudos ecológicos, necessários à proposição de medidas que permitirão a conservação da espécie nesta baía.
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- 2024
68. Changing trends in clinical characteristics and in-hospital mortality of patients with infective endocarditis over four decades
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Diego Augusto Medeiros Santos, Rinaldo Focaccia Siciliano, Bruno Adler Maccagnan Pinheiro Besen, Tania Mara Varejão Strabelli, Caio Trevelin Sambo, Vitor de Medeiros Milczwski, Flora Goldemberg, Flavio Tarasoutchi, Marcelo Luiz Campos Vieira, Milena Ribeiro Paixão, Danielle Menosi Gualandro, Tarso Augusto Duenhas Accorsi, Pablo Maria Alberto Pomerantzeff, and Alfredo José Mansur
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Infective endocarditis ,Heart valve prosthesis implantation ,Cohort studies ,Infectious and parasitic diseases ,RC109-216 ,Public aspects of medicine ,RA1-1270 - Abstract
Background: Infective endocarditis continues to be a significant concern and may be undergoing an epidemiological transition. Methods: Were studied 1804 consecutive episodes of infective endocarditis between 1978 and 2022. The mean age was 48 ( ± 19), and 1162 (64%) patients were male. Temporal trends in demographic data, comorbidities, predisposing conditions, microorganisms, complications and in-hospital death have been studied over the decades (1978–1988, 1989–1999, 2000–2010 and 2011–2022). The outcomes and clinical characteristics were modeled using nonlinear cubic spline functions. Findings: Valve surgery was performed in 50% of the patients and overall in-hospital mortality was 30%. From the first to the fourth decade studied, the average age of patients increased from 29 to 57 years (p
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- 2024
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69. One-neutron stripping process in the 209Bi(6Li, 5Li)210Bi* reaction reaction
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Zhang, Gao-Long, Jiao, Zhen-Wei, Zhang, Guang-Xin, Cardozo, E. N., Paes, B., Hu, Shi-Peng, Qian, Jian-Qiang, Mengoni, Daniele, Qu, Wei-Wei, Li, Cong-Bo, Zheng, Yun, Zhang, Huan-Qiao, Sun, Hui-Bin, Wang, Nan, Zhang, Chun-Lei, Valiente-Dobón, J. J., Testov, D., Mazzocco, M., Gozzelino, A., Parascandolo, C., Pierroutsakou, D., La Commara, M., Goasduff, A., Bazzacco, D., Napoli, D. R., Galtarossa, F., Recchia, F., Illana, A., Bakes, S., Zanon, I., Aydin, S., de Angelis, G., Siciliano, M., Menegazzo, R., Lenzi, S. M., Akkoyun, S., Canto, L. F., and Lubian, J.
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- 2024
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70. Search for $^{22}$Na in novae supported by a novel method for measuring femtosecond nuclear lifetimes
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Fougères, C., Santos, F. de Oliveira, José, J., Michelagnoli, C., Clément, E., Kim, Y. H., Lemasson, A., Guimaraes, V., Barrientos, D., Bemmerer, D., Benzoni, G., Boston, A. J., Bottger, R., Boulay, F., Bracco, A., Celikovic, I., Cederwall, B., Ciemala, M., Delafosse, C., Domingo-Pardo, C., Dudouet, J., Eberth, J., Fulop, Z., Gonzalez, V., Goupil, J., Hess, H., Jungclaus, A., Kaskas, A., Korichi, A., Lenzi, S. M., Leoni, S., Li, H., Ljungvall, J., Lopez-Martens, A., Menegazzo, R., Mengoni, D., Million, B., Mrazek, J., Napoli, D. R., Navin, A., Nyberg, J., Podolyak, Zs., Pullia, A., Quintana, B., Ralet, D., Redon, N., Reiter, P., Rezynkina, K., Saillant, F., Salsac, M. D., Sanchez-Benitez, A. M., Sanchis, E., Senyigit, M., Siciliano, M., Smirnova, N. A., Sohler, D., Stanoiu, M., Theisen, Ch., Valiente-Dobon, J. J., Ujic, P., and Zielinska, M.
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Nuclear Experiment ,Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Classical novae are thermonuclear explosions in stellar binary systems, and important sources of $^{26}$Al and $^{22}$Na. While gamma rays from the decay of the former radioisotope have been observed throughout the Galaxy, $^{22}$Na remains untraceable. The half-life of $^{22}$Na (2.6 yr) would allow the observation of its 1.275 MeV gamma-ray line from a cosmic source. However, the prediction of such an observation requires good knowledge of the nuclear reactions involved in the production and destruction of this nucleus. The $^{22}$Na($p,\gamma$)$^{23}$Mg reaction remains the only source of large uncertainty about the amount of $^{22}$Na ejected. Its rate is dominated by a single resonance on the short-lived state at 7785.0(7) keV in $^{23}$Mg. In the present work, a combined analysis of particle-particle correlations and velocity-difference profiles is proposed to measure femtosecond nuclear lifetimes. The application of this novel method to the study of the $^{23}$Mg states, combining magnetic and highly-segmented tracking gamma-ray spectrometers, places strong limits on the amount of $^{22}$Na produced in novae, explains its non-observation to date in gamma rays (flux < 2.5x$10^{-4}$ ph/(cm$^2$s)), and constrains its detectability with future space-borne observatories., Comment: 18 pages, 3 figures, 1 table
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- 2022
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71. A construção de um ethos moderno no Rio de Janeiro: revistas ilustradas e objetos publicizados
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Melba Santos Porter de Souza Santos Porter de Souza and Tatiana Siciliano
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Revistas ilustradas ,Modernidade ,Rio de Janeiro ,Publicidade ,Objetos ,Communication. Mass media ,P87-96 ,Social sciences (General) ,H1-99 - Abstract
Por meio da análise de objetos e aparatos tecnológicos publicizados em propagandas da Kósmos, revista ilustrada e importante suporte documental dos primeiros anos do século XX, este artigo buscou alcançar entendimento sobre como a sociedade carioca assimilou a modernização da Capital Federal, que efeitos produziu a interação com carros, com bondes elétricos, máquinas pe-sadas e outros modernismos que iam além das de ordem urbana, representados na imprensa da época. Para o estudo, foram analisadas todas as edições dos seis anos de publicação do impressoperiódico. Como demonstrado no estudo, a hipótese é que, como “janelas” para o entendimentoda cultura moderna, os aparatos tecnológicos e outros objetos publicizados nas páginas da imprensa trouxeram mais que revelações de como se deu a reconfiguração do espaço público, das novas formas de ver e ser na relação com a modernidade. Com simbologias próprias, auxiliaram na aspiração e na construção de um novo valor moral, seu caráter e um novo estilo de vida paraos cariocas.
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- 2024
72. Impact of Hemoglobin Levels on Composite Cardiac Arrest or Stroke Outcome in Patients With Respiratory Failure Due to COVID-19
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Shi Nan Feng, BSPH, Thu-Lan Kelly, PhD, John F. Fraser, MD, PhD, Gianluigi Li Bassi, MD, PhD, Jacky Suen, PhD, Akram Zaaqoq, MD, MPH, Matthew J. Griffee, MD, Rakesh C. Arora, MD, Nicole White, PhD, Glenn Whitman, MD, Chiara Robba, MD, PhD, Denise Battaglini, MD, PhD, Sung-Min Cho, DO, MHS, on behalf of COVID-19 Critical Care Consortium (CCCC), Robert Bartlett, John F. Fraser, Gianluigi Li Bassi, Jacky Y. Suen, Heidi J. Dalton, John Laffey, Daniel Brodie, Eddy Fan, Antoni Torres, Davide Chiumello, Alyaa Elhazm, Carol Hodgson, Shingo Ichiba, Carlos Luna, Srinivas Murthy, Alistair Nichol, Pauline Yeung Ng, Mark Ogino, Aidan Burrell, Antonio Pesenti, Tala Al-Dabbous, Huda Alfoudri, Mohammed Shamsah, Subbarao Elapavaluru, Ashley Berg, Christina Horn, Yunis Mayasi, Stephan Schroll, Dan Meyer, Jorge Velazco, Ludmyla Ploskanych, Wanda Fikes, Rohini Bagewadi, Marvin Dao, Haley White, Alondra Berrios Laviena, Ashley Ehlers Maysoon, Shalabi-McGuire, Trent Witt, Lorenzo Grazioli, Luca Lorini, E. Wilson Grandin, Jose Nunez, Tiago Reyes, Diarmuid O’Briain, Stephanie Hunter, Mahesh Ramanan, Julia Affleck, Hemanth Hurkadli Veerendra, Sumeet Rai, Josie Russell-Brown, Mary Nourse, Mark Joseph, Brook Mitchell, Martha Tenzer, Ryuzo Abe, Hwa Jin Cho, In Seok Jeong, Nadeem Rahman, Vivek Kakar, Andres Oswaldo Razo Vazquez, Nicolas Brozzi, Omar Mehkri, Sudhir Krishnan Abhijit, Duggal Stuart Houltham, Jerónimo Graf, Roderigo Diaz, Roderigo Orrego, Camila Delgado, Joyce González, Maria Soledad Sanchez, Michael Piagnerelli, Josefa Valenzuela Sarrazin, A/Prof. Gustavo Zabert, Lucio Espinosa, Paulo Delgado, Victoria Delgado, Diego Fernando, Bautista Rincón, Angela Maria Marulanda Yanten, Melissa Bustamante Duque, Alyaa Elhazmi, Abdullah Al-Hudaib, Maria Callahan, M. Azhari Taufik, Elizabeth Yasmin Wardoyo, Margaretha Gunawan, Nurindah S Trisnaningrum, Vera Irawany, Muhammad Rayhan, Mauro Panigada, Alberto Zanella, Giacomo Grasselli, Sebastiano Colombo, Chiara Martinet, Gaetano Florio, Massimo Antonelli, Simone Carelli, Domenico L. Grieco, Motohiro Asaki, Kota Hoshino, Leonardo Salazar, Mary Alejandra Mendoza Monsalve, Bairbre McNicholas, David Cosgrave, Joseph McCaffrey, Allison Bone, Yusuff Hakeem, James Winearls, Mandy Tallott, David Thomson, Christel Arnold-Day, Jerome Cupido, Zainap Fanie, Malcom Miller, Lisa Seymore, Dawid van Straaten, Ali Ait Hssain, Jeffrey Aliudin, Al-Reem Alqahtani, Khoulod Mohamed, Ahmed Mohamed, Darwin Tan, Joy Villanueva, Ahmed Zaqout, Ethan Kurtzman, Arben Ademi, Ana Dobrita, Khadija El Aoudi, Juliet Segura, Gezy Giwangkancana, Shinichiro Ohshimo, Javier Osatnik, Anne Joosten, Minlan Yang, Ana Motos, Francisco Arancibia, Virginie Williams, Alexandre Noel, Nestor Luque, Marina Fantini, Ruth Noemi Jorge García, Enrique Chicote Alvarez, Anna Greti, Adrian Ceccato, Angel Sanchez, Ana Loza Vazquez, Ferran Roche-Campo, Diego Franch-Llasat, Divina Tuazon, Marcelo Amato, Luciana Cassimiro, Flavio Pola, Francis Ribeiro, Guilherme Fonseca, Heidi Dalton, Mehul Desai, Erik Osborn Hala Deeb, Antonio Arcadipane, Gennaro Martucci, Giovanna Panarello, Chiara Vitiello, Claudia Bianco, Giovanna Occhipinti, Matteo Rossetti, Raffaele Cuffaro, Sung-Min Cho, Glenn Whitman, Hiroaki Shimizu, Naoki Moriyama, Jae-Burm Kim, Nobuya Kitamura, Johannes Gebauer, Toshiki Yokoyama, Abdulrahman Al-Fares, Sarah Buabbas, Esam Alamad, Fatma Alawadhi, Kalthoum Alawadi, Hiro Tanaka, Satoru Hashimoto, Masaki Yamazaki, Tak-Hyuck Oh, Mark Epler, Cathleen Forney, Louise Kruse, Jared Feister, Joelle Williamson, Katherine Grobengieser, Eric Gnall, Sasha Golden, Mara Caroline, Timothy Shapiro, Colleen Karaj, Lisa Thome, Lynn Sher, Mark Vanderland, Mary Welch, Sherry McDermott, Matthew Brain, Sarah Mineall, Dai Kimura, Luca Brazzi, Gabriele Sales, Giorgia Montrucchio, Tawnya Ogston, Dave Nagpal, Karlee Fischer, Roberto Lorusso, Rajavardhan Rangappa, Sujin Rai, Argin Appu, Mariano Esperatti, Nora Angélica Fuentes, Maria Eugenia Gonzalez, Edmund G. Carton, Ayan Sen, Amanda Palacios, Deborah Rainey, Gordan Samoukoviv, Josie Campisi, Lucia Durham, Emily Neumann, Cassandra Seefeldt, Octavio Falcucci, Amanda Emmrich, Jennifer Guy, Carling Johns, Kelly Potzner, Catherine Zimmermann, Angelia Espinal, Nina Buchtele, Michael Schwameis, Andrea Korhnfehl, Roman Brock, Thomas Staudinger, Stephanie-Susanne, Stecher Michaela Barnikel, Sófia Antón, Alexandra Pawlikowski, Akram Zaaqoq, Lan Anh Galloway, Caitlin Merley, Marc Csete, Luisa Quesada, Isabela Saba, Daisuke Kasugai, Hiroaki Hiraiwa, Taku Tanaka, Eva Marwali, Yoel Purnama, Santi Rahayu Dewayanti, Ardiyan, Dafsah Arifa Juzar, Debby Siagian, Yih-Sharng Chen, Indrek Ratsep, Andra-Maris Post, Piret Sillaots, Anneli Krund, Merili-Helen Lehiste, Tanel Lepik, Frank Manetta, Effe Mihelis, Iam Claire Sarmiento, Mangala Narasimhan, Michael Varrone, Mamoru Komats, Julia Garcia-Diaz, Catherine Harmon, S. Veena Satyapriya, Amar Bhatt, Nahush A. Mokadam, Alberto Uribe, Alicia Gonzalez, Haixia Shi, Johnny McKeown, Joshua Pasek, Juan Fiorda, Marco Echeverria, Rita Moreno, Bishoy Zakhary, Marco Cavana, Alberto Cucino, Giuseppe Foti, Marco Giani, Benedetta Fumagalli, Valentina Castagna, Andrea Dell’Amore, Paolo Navalesi, Hoi-Ping Shum, Alain Vuysteke, Asad Usman, Andrew Acker, Benjamin Smood, Blake Mergler, Federico Sertic, Madhu Subramanian, Alexandra Sperry, Nicolas Rizer, Erlina Burhan, Menaldi Rasmin, Ernita Akmal, Faya Sitompul, Navy Lolong, Bhat Naivedh, Simon Erickson, Peter Barrett, David Dean, Julia Daugherty, Antonio Loforte, Irfan Khan, Mohammed Abraar Quraishi, Olivia DeSantis, Dominic So, Darshana Kandamby, Jose M. Mandei, Hans Natanael, Eka YudhaLantang, Anastasia Lantang, Surya Oto Wijaya, Anna Jung, George Ng, Wing Yiu Ng, Shu Fang, Alexis Tabah, Megan Ratcliffe, Maree Duroux, Shingo Adachi, Shota Nakao, Pablo Blanco, Ana Prieto, Jesús Sánchez, Meghan Nicholson, Warwick Butt, Alyssa Serratore, Carmel Delzoppo, Pierre Janin, Elizabeth Yarad, Richard Totaro, Jennifer Coles, Bambang Pujo, Robert Balk, Andy Vissing, Esha Kapania, James Hays, Samuel Fox, Garrett Yantosh, Pavel Mishin, Saptadi Yuliarto, Kohar Hari Santoso, Susanthy Djajalaksana, Arie Zainul Fatoni, Masahiro Fukuda, Keibun Liu, Paolo Pelosi, Denise Battaglini, Juan Fernando Masa Jiménez, Diego Bastos, Sérgio Gaião, Desy Rusmawatiningtyas, Young-Jae Cho, Su Hwan Lee, Tatsuya Kawasaki, Laveena Munshi, Pranya Sakiyalak, Prompak Nitayavardhana, Tamara Seitz, Rakesh Arora, David Kent, Daniel Marino, Swapnil Parwar, Andrew Cheng, Jennene Miller, Shigeki Fujitani, Naoki Shimizu, Jai Madhok, Clark Owyang, Hergen Buscher, Claire Reynolds, Olavi Maasikas, Aleksan Beljantsev, Vladislav Mihnovits, Takako Akimoto, Mariko Aizawa, Kanako Horibe, Ryota Onodera, Meredith Young, Timothy George, Kiran Shekar, Niki McGuinness, Lacey Irvine, Brigid Flynn, Tomoyuki Endo, Kazuhiro Sugiyama, Keiki Shimizu, Kathleen Exconde, Leslie Lussier, Gösta Lotz, Maximilian Malfertheiner, Lars Maier, Esther Dreier, Neurinda Permata Kusumastuti, Colin McCloskey, Al-Awwab Dabaliz, Tarek B Elshazly, Josiah Smith, Konstanty S. Szuldrzynski, Piotr Bielański, Keith Wille, Ken Kuljit, S. Parhar, Kirsten M. Fiest, Cassidy Codan, Anmol Shahid, Mohamed Fayed, Timothy Evans, Rebekah Garcia, Ashley Gutierrez, Tae Song, Rebecca Rose, Suzanne Bennett, Denise Richardson, Giles Peek, Lovkesh Arora, Kristina Rappapport, Kristina Rudolph, Zita Sibenaller, Lori Stout, Alicia Walter, Daniel Herr, Nazli Vedadi, Shaun Thompson, Julie Hoffman, Xiaonan Ying, Ryan Kennedy, Muhammed Elhadi, Matthew Griffee, Anna Ciullo, Yuri Kida, Ricard Ferrer Roca, JordI Riera, Sofia Contreras, Cynthia Alegre, Christy Kay, Irene Fischer, Elizabeth Renner, Hayato Taniguci, John Fraser, Jacky Suen, Adrian Barnett, Nicole White, Kristen Gibbons, Simon Forsyth, Amanda Corley, India Pearse, Samuel Hinton, Gabriella Abbate, Halah Hassan, Silver Heinsar, Varun A Karnik, Katrina Ki, Hollier F. O’Neill, Nchafatso Obonyo, Leticia Pretti Pimenta, Janice D. Reid, Kei Sato, Aapeli Vuorinen, Karin S. Wildi, Emily S. Wilson, Stephanie Yerkovich, James Lee, Daniel Plotkin, Barbara Wanjiru Citarella, Laura Merson, Emma Hartley, Bastian Lubis, Takanari Ikeyama, Balu Bhaskar, Jae-Seung Jung, Shay McGuinness, Glenn Eastwood, Sandra Rossi Marta, Fabio Guarracino, Stacy Gerle, Emily Coxon, Bruno Claro, Daniel Loverde, Namrata Patil, Vieri Parrini, Angela McBride, Kathryn Negaard, Angela Ratsch, Ahmad Abdelaziz, Juan David Uribe, Adriano Peris, Mark Sanders, Dominic Emerson, Muhammad Kamal, Pedro Povoa, Roland Francis, Ali Cherif, Sunimol Joseph, Matteo Di Nardo, Micheal Heard, Kimberly Kyle, Ray A Blackwell, Patrick Biston, Hye Won Jeong, Reanna Smith, Yogi Prawira, Arturo Huerta Garcia, Nahikari Salterain, Bart Meyns, Marsha Moreno, Rajat Walia, Amit Mehta, Annette Schweda, Moh Supriatna, Cenk Kirakli, Melissa Williams, Kyung Hoon Kim, Alexandra Assad, Estefania Giraldo, Wojtek Karolak, Martin Balik, Elizabeth Pocock, Evan Gajkowski, Kanamoto Masafumi, Nicholas Barrett, Yoshihiro Takeyama, Sunghoon Park, Faizan Amin, Fina Meilyana Andriyani, Serhii Sudakevych, Magdalena Vera, Rodrigo Cornejo, Patrícia Schwarz, Ana Carolina Mardini, Thais de Paula, Ary Serpa Neto, Andrea Villoldo, Alexandre Siciliano Colafranceschi, Alejandro Ubeda Iglesias, Juan Granjean, Lívia Maria Garcia Melro, Giovana Fioravante Romualdo, Diego Gaia, Helmgton Souza, Filomena Galas, Rafael Máñez Mendiluce, Alejandra Sosa, Ignacio Martinez, Hiroshi Kurosawa, Juan Salgado, Beate Hugi-Mayr, Eric Charbonneau, Vitor Salvatore Barzilai, Veronica Monteiro, Rodrigo Ribeiro de Souza, Michael Harper, Hiroyuki Suzuki, Celina Adams, Jorge Brieva, George Nyale, Faisal Saleem Eltatar, Jihan Fatani, Husam Baeissa, Ayman AL Masri, Ahmed Rabie, Mok Yee Hui, Masahiro Yamane, Hanna Jung, Ayorinde Mojisola Margaret, Newell Nacpil, Katja Ruck, Rhonda Bakken, Claire Jara, Tim Felton, Lorenzo Berra, Bobby Shah, Arpan Chakraborty, Monika Cardona, Gerry Capatos, Bindu Akkanti, Abiodun Orija, Harsh Jain, Asami Ito, Brahim Housni, Sennen Low, Koji Iihara, Joselito Chavez, Kollengode Ramanathan, Gustavo Zabert, Krubin Naidoo, Ian Seppelt, Marlice VanDyk, Sarah MacDonald, Randy McGregor, Teka Siebenaler, Hannah Flynn, Kristi Lofton, Toshiyuki Aokage, Kazuaki Shigemitsu, Andrea Moscatelli, Giuseppe Fiorentino, Matthias Baumgaertel, Serge Eddy Mba, Jana Assy, Amelya Hutahaean, Holly Roush, Kay A Sichting, Francesco Alessandri, Debra Burns, Gavin Salt, Carl P. Garabedian, Jonathan Millar, Malcolm Sim, Adrian Mattke, Danny McAuley, Jawad Tadili, Tim Frenzel, Yaron Bar-Lavie, Aaron Blandino Ortiz, Jackie Stone, Antony Attokaran, Michael Farquharson, Brij Patel, Derek Gunning, Kenneth Baillie, Pia Watson, Kenji Tamai, Gede Ketut Sajinadiyasa, Dyah Kanyawati, Marcello Salgado, Assad Sassine, Bhirowo Yudo, Scott McCaul, Bongjin Lee, Sang Min Lee, Arnon Afek, Yoshiaki Iwashita, Bambang Pujo Semedi, Jack Metiva, Nicole Van Belle, Ignacio Martin-Loeches, Lenny Ivatt, Chia Yew Woon, Hyun Mi Kang, Timothy Smith, Erskine James, Nawar Al-Rawas, Yudai Iwasaki, Kenny Chan King-Chung, Vadim Gudzenko, Fabio Taccone, Fajar Perdhana, Yoan Lamarche, Joao Miguel Ribeiro, Nikola Bradic, Klaartje Van den Bossche, Oude Lansink, Gurmeet Singh, Gerdy Debeuckelaere, Henry T. Stelfox, Cassia Yi, Jennifer Elia, Thomas Tribble, Shyam Shankar, Raj Padmanabhan, Bill Hallinan, Luca Paoletti, Yolanda Leyva, Tatuma Fykuda, Jenelle Badulak, Jillian Koch, Amy Hackman, Lisa Janowaik, Deb Hernandez, Jennifer Osofsky, Katia Donadello, Aizah Lawang, Josh Fine, and Benjamin Davidson
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Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
OBJECTIVES:. Anemia has been associated with an increased risk of both cardiac arrest and stroke, frequent complications of COVID-19. The effect of hemoglobin level at ICU admission on a composite outcome of cardiac arrest or stroke in an international cohort of COVID-19 patients was investigated. DESIGN:. Retrospective analysis of prospectively collected database. SETTING:. A registry of COVID-19 patients admitted to ICUs at over 370 international sites was reviewed for patients diagnosed with cardiac arrest or stroke up to 30 days after ICU admission. Anemia was defined as: normal (hemoglobin ≥ 12.0 g/dL for women, ≥ 13.5 g/dL for men), mild (hemoglobin 10.0–11.9 g/dL for women, 10.0–13.4 g/dL for men), moderate (hemoglobin ≥ 8.0 and < 10.0 g/dL for women and men), and severe (hemoglobin < 8.0 g/dL for women and men). PATIENTS:. Patients older than 18 years with acute COVID-19 infection in the ICU. INTERVENTIONS:. None. MEASUREMENTS AND MAIN RESULTS:. Of 6926 patients (median age = 59 yr, male = 65%), 760 patients (11.0%) experienced stroke (2.0%) and/or cardiac arrest (9.4%). Cardiac arrest or stroke was more common in patients with low hemoglobin, occurring in 12.8% of patients with normal hemoglobin, 13.3% of patients with mild anemia, and 16.7% of patients with moderate/severe anemia. Time to stroke or cardiac arrest by anemia status was analyzed using Cox proportional hazards regression with death as a competing risk. Covariates selected through clinical knowledge were age, sex, comorbidities (diabetes, hypertension, obesity, and cardiac or neurologic conditions), pandemic era, country income, mechanical ventilation, and extracorporeal membrane oxygenation. Moderate/severe anemia was associated with a higher risk of cardiac arrest or stroke (hazard ratio, 1.32; 95% CI, 1.05–1.67). CONCLUSIONS:. In an international registry of ICU patients with COVID-19, moderate/severe anemia was associated with increased hazard of cardiac arrest or stroke.
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- 2024
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73. Probabilistic Bayesian Neural Networks for olive phenology prediction in precision agriculture
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A. Nappa, M. Quartulli, I. Azpiroz, S. Marchi, D. Guidotti, M. Staiano, and R. Siciliano
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Olive phenology ,Modeling neural networks ,Bayesian inference ,Monte Carlo Dropout ,Precision agriculture ,Information technology ,T58.5-58.64 ,Ecology ,QH540-549.5 - Abstract
Plant phenology is the study of cyclical events in a plant life cycle such as leaf bud burst, flowering, and fruiting. In this article the problem of olive phenology prediction is addressed through the use of Deep Learning. Although Neural Networks have already been used in this area, to the best of our knowledge, this is the first implementation of Probabilistic Bayesian Neural Networks for olive phenology prediction. This architecture gives particular emphasis to estimating the model uncertainty, both aleatoric and epistemic. The Bayesian Inference method, more precisely the Variational Inference one, is compared with the Monte Carlo Dropout technique, which is known to be a less computationally intensive approximation of Variational Inference. For validation purposes, models performance is compared to the state-of-the-art results.
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- 2024
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74. Portability rules detection by Epilepsy Tracking META-Set Analysis
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Christian Riccio, Roberta Siciliano, Michele Staiano, Giuseppe Longo, Luigi Pavone, and Gaetano Zazzaro
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Complexity measures ,Data mining ,EEG analysis ,Machine learning ,Meta-analysis ,Seizures detection ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Epilepsy is a severe and common neurological disease that causes sudden and irregular seizures, necessitating patient-specific detection models for effective management. The proposed methodology, Epilepsy Tracking META-Set Analysis, establishes portability rules that identify similar patients, enabling the transfer of these detection models from one patient to another. Main issue is to identify clusters of patients analyzing a set of meta-features of each patient in terms of clinical descriptors, performance metrics of a machine learning model for seizure detection, and data complexity measures. The investigation of complexity measures represents a novelty in such a medical field, allowing to compare patients and to support automated seizure detection methods. The proposed methodology is validated using the well-known Epileptic Seizure EEG Database from the Epilepsy Center of the University Hospital of Freiburg and demonstrates promising results in transferring detection models to new cases.
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- 2024
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75. Diretriz sobre Diagnóstico e Tratamento da Cardiomiopatia Hipertrófica – 2024
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Fabio Fernandes, Marcus V. Simões, Edileide de Barros Correia, Fabiana Goulart Marcondes-Braga, Otavio Rizzi Coelho-Filho, Cláudio Tinoco Mesquita, Wilson Mathias Junior, Murillo de Oliveira Antunes, Edmundo Arteaga-Fernández, Carlos Eduardo Rochitte, Felix José Alvarez Ramires, Silvia Marinho Martins Alves, Marcelo Westerlund Montera, Renato Delascio Lopes, Mucio Tavares de Oliveira Junior, Fernando Luis Scolari, Walkiria Samuel Avila, Manoel Fernandes Canesin, Edimar Alcides Bocchi, Fernando Bacal, Lidia Zytynski Moura, Eduardo Benchimol Saad, Mauricio Ibrahim Scanavacca, Bruno Pereira Valdigem, Manuel Nicolas Cano, Alexandre Antonio Cunha Abizaid, Henrique Barbosa Ribeiro, Pedro Alves Lemos Neto, Gustavo Calado de Aguiar Ribeiro, Fabio Biscegli Jatene, Ricardo Ribeiro Dias, Luis Beck-da-Silva, Luis Eduardo Paim Rohde, Marcelo Imbroinise Bittencourt, Alexandre da Costa Pereira, José Eduardo Krieger, Humberto Villacorta Junior, Wolney de Andrade Martins, José Albuquerque de Figueiredo Neto, Juliano Novaes Cardoso, Carlos Alberto Pastore, Ieda Biscegli Jatene, Ana Cristina Sayuri Tanaka, Viviane Tiemi Hotta, Minna Moreira Dias Romano, Denilson Campos de Albuquerque, Ricardo Mourilhe-Rocha, Ludhmila Abrahão Hajjar, Fabio Sandoli de Brito Junior, Bruno Caramelli, Daniela Calderaro, Pedro Silvio Farsky, Alexandre Siciliano Colafranceschi, Ibraim Masciarelli Francisco Pinto, Marcelo Luiz Campos Vieira, Luiz Claudio Danzmann, Silvio Henrique Barberato, Charles Mady, Martino Martinelli Filho, Ana Flavia Malheiros Torbey, Pedro Vellosa Schwartzmann, Ariane Vieira Scarlatelli Macedo, Silvia Moreira Ayub Ferreira, Andre Schmidt, Marcelo Dantas Tavares de Melo, Moysés Oliveira Lima Filho, Andrei C. Sposito, Flávio de Souza Brito, Andreia Biolo, Vagner Madrini Junior, Stephanie Itala Rizk, and Evandro Tinoco Mesquita
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Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Published
- 2024
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76. Editorial: Sleep disorders in neuromuscular diseases: treatable conditions: the evolving scenario of sleep in neuromuscular disorders
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Corrado Italo Angelini, Gabriele Siciliano, and Carl Ansevin
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sleep ,SMA ,charcot-marie tooth ,advances ,drug ,sleep apnea ,Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
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77. Spinal manipulation and mobilization forces delivered treating sciatica: a case report
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Theodore B. Siciliano, Maruti R. Gudavalli, and Ralph Kruse
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force-based spinal manipulation ,sciatica ,Cox Technic flexion distraction decompression spinal manipulation ,case report ,low back pain ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
IntroductionAccurately measuring the forces applied during spinal manipulation and its biomechanical effects on the spine are critically important in current research. This single case report discusses the potential benefit of accurately monitoring manipulative forces in treating low back pain with sciatica. The type of force-based spinal manipulation used to manage this case was Cox Technic flexion distraction decompression (CTFDD) spinal manipulation care, along with other ancillary modalities.MethodsThe treatment plan, in this case, was primarily force-based CTFDD, equal-force bi-directional traction (EqFT), pre-modulated electrical muscle stimulation (EMS), infrared light therapy (ILT), and a home stretching and strengthening program.Clinical findingsInitially, the case study patient presented with complaints of left lumbar spine pain, which radiated into the left buttock, down the left leg, accompanied by an inability to dorsiflex the left foot. The patient was concerned with this condition as the left leg pain and left lower extremity motor deficit were having a profound effect on the patient’s ability to perform activities of daily living and work. The patient was recommended to undergo spinal decompression surgery, which the patient did not want, and elected to exhaust all alternative, non-surgical treatments first.Diagnosis, intervention, and outcomesA diagnosis of sciatica with a sequestered disk fragment and left lower extremity motor deficit was rendered through objective physical examination results and a review of a lumbar MRI study. Past interventions included prescription medications, physical rehabilitation, chiropractic, pain management, and neurosurgical consultation. All past interventions prior to initiating CTFDD care provided minimal subjective and/or objective clinical improvement. This patient had a positive clinical outcome from a force-based CTFDD treatment plan along with other modalities consisting of pre-modulated EMS, ILT, and a home stretching and strengthening program.ConclusionForce-based CTFDD spinal manipulation, along with other modalities consisting of pre-modulated EMS, ILT, and a home stretching and strengthening program, has been found to be an alternative, non-surgical treatment for discogenic sciatica. Continued research is needed on force-based CTFDD spinal manipulation to further evaluate the neurological and biomechanical effects of the forces and motion applied to the spine and determine health benefits for the treatment of low back pain.
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- 2024
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78. Excessive daytime sleepiness in myotonic dystrophy: a narrative review
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Domeniko Hoxhaj, Alessia Pascazio, Michelangelo Maestri, Giulia Ricci, Monica Fabbrini, Francesca Buracchi Torresi, Gabriele Siciliano, and Enrica Bonanni
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neuromuscolar disorders ,sleep disorder ,myotonic distrophies ,sleepeness ,genetic disorder ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
IntroductionExcessive daytime sleepiness (EDS) is a common and debilitating symptom in both forms of myotonic dystrophy (DM), significantly impacting patients’ quality of life. The review focuses on the purpose of examining the current understanding of EDS in these conditions, the difficulty in correctly accessing it, the recent findings related to its etiology and prevalence, and a summary of potential therapeutic implications.MethodsWe conducted a comprehensive search through PubMed, selecting studies that provided significant insights into the mechanisms, prevalence, and management of EDS in DM1 and DM2.Results and discussionEDS is highly prevalent in both DM1 and DM2. Polysomnographic studies have revealed prominent dysregulation of REM sleep in DM1, suggesting a possible narcoleptic-like phenotype and alterations in NREM sleep that contributes to daytime sleepiness. Other factors have been proposed to explain EDS in DM1, including dysregulation of the sleep-wake circadian rhythm through nocturnal actigraphy analysis. The central origin of EDS is increasingly delineated supported by serotonin and orexin pathways dysfunction, and recent neuroradiological findings showing that in DM1 hippocampus volume was positively correlated with self-reported fatigue and somnolence. Sleep-disordered breathing and respiratory dysfunctions are prevalent in DM, their direct correlation with EDS remains complex and inconclusive, but respiratory evaluation should be recommended if obstructive sleep apneas or respiratory muscle dysfunctions are suspected. Drug interventions, such as modafinil and mexiletine, have shown promise in managing excessive daytime sleepiness and reducing myotonia without significant cardiac conduction effects. Enhancing EDS management in myotonic dystrophy is key to improving overall patient well-being.
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- 2024
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79. Risk of SARS-CoV-2 infection in patients with hematologic diseases receiving tixagevimab/cilgavimab as pre-exposure prophylaxis in most recent Omicron sublineages era
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Alessandra Vergori, Alessandro Cozzi Lepri, Marta Chiuchiarelli, Valentina Mazzotta, Elisabetta Metafuni, Giulia Matusali, Valentina Siciliano, Jessica Paulicelli, Eleonora Alma, Agostina Siniscalchi, Simona Sica, Elisabetta Abruzzese, Massimo Fantoni, Andrea Antinori, and Antonella Cingolani
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SARS-CoV-2 ,COVID-19 ,Hematologic disease ,Pre-exposure prophylaxis ,Tixagevimab/cilgavimab ,Infectious and parasitic diseases ,RC109-216 - Abstract
Objectives: Whether pre-exposure prophylaxis (PrEP) with tixagevimab/cilgavimab 150 mg/150 mg (T/C) in individuals with hematologic disease (HD) may lead to a reduced risk of SARS-CoV-2 breakthrough infection (BTI)/hospitalization, or death in the Omicron era remains to be established. Methods: An observational study included participants with HD who received PrEP. BTIs were defined as SARS-CoV-2 positivity by reverse transcription-polymerase chain reaction. The incidence of BTIs (95% CI) and of BTIs/hospitalization/death was calculated using the Kaplan-Meier method and as the number of BTIs per 100 person-years of follow-up according to the circulating variant of concern (VoC). A Poisson regression model was used to evaluate the association between the rate of incidence and circulating VoCs after controlling for demographics and clinical factors. Results: We included 550 HD patients: 71% initiated T/C PrEP when BA.5 was the most prevalent, followed by XBB/EG, BA.2, and BA.1 (19%, 7%, and 3%, respectively). Overall, the 1-year incidence estimate of BTIs/hospitalization/death was 24% (18.7-29.4%). A greater risk of incident infections was observed when BA.5 and XBB/EG sub-lineages circulated (aRR 5.05 [2.17, 11.77]; P < .001 and 3.82 [1.50, 9.7]; P = 0.005, compared to BA.1, respectively). Conclusions: The 1-year incidence of SARS-CoV-2 BTIs/hospitalization/death was 24% which is in line with what was observed in other similar studies. The risk appeared to be higher when more recent Omicron sub-lineages were circulating suggesting a reduction of in vitro neutralization.
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- 2024
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80. The rate of the astrophysical 48Cr(p,γ)49Mn reaction and its influence on the potential A = 48 waiting point in the rp process
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C. O'Shea, G. Lotay, D.T. Doherty, D. Seweryniak, R. Lau, G. Bartram, S. Byrne, L. Canete, M.P. Carpenter, K.A. Chipps, P.A. Copp, C. Cousins, J. Henderson, T. Huang, H. Jayatissa, F. Kondev, C. Müller-Gatermann, S.D. Pain, C. Paxman, B.J. Reed, W. Reviol, A.M. Rogers, R. Russell, H. Schatz, and M. Siciliano
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Nuclear astrophysics ,Gamma-ray spectroscopy ,X-ray bursts ,Physics ,QC1-999 - Abstract
We have performed a detailed γ-ray spectroscopy study of the nucleus, 49Mn, using the GRETINA tracking array and FMA recoil separator. With this powerful new setup, low-spin excited states, which are most relevant for astrophysical processes, have been identified for the first time, including four proton-unbound levels, corresponding to key astrophysical resonances in the 48Cr(p,γ)49Mn reaction. Of these four levels, two were found to dominate the 48Cr(p,γ)49Mn reaction for temperatures, T = 0.2 − 1.4 GK, and uncertainties in the rate have been reduced by more than 3 orders of magnitude. Specifically, γ decays were observed from 1/2+ and 3/2− excited states at Ex = 2570.9(26) keV and 2595.8(21) keV, corresponding to an ℓ = 0 and ℓ = 1 resonance in the 48Cr + p system at Er = 482.9(84) keV and 507.9(83) keV, respectively. Present simulations of Type-I X-ray burst nucleosynthesis indicate that the newly defined 48Cr(p,γ) reaction rate is sufficiently fast to drive the flow of material towards higher masses in such environments. Consequently, despite the relatively long half life of 48Cr, we now do not expect a strong waiting point in the rp process at A = 48.
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- 2024
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81. Implantación y uso de la telemedicina en la asistencia sanitaria del brote de viruela símica en el Área de Salud de Ibiza y Formentera
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Beatriz Siciliano, Susana Ramon, Jimena Gabrielli, and Aránzazu López-López
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Telemedicine ,Monkeypox virus ,Clinical control ,Primary care ,Medicine (General) ,R5-920 - Abstract
Resumen: Objetivo: El objetivo de este trabajo es describir cómo se han utilizado las tecnologías de la información y la comunicación en el control clínico, el seguimiento, el tratamiento y el alta de pacientes afectados de viruela símica. Diseño y lugar: Se ha realizado un estudio descriptivo, observacional y retrospectivo de todos los casos de viruela símica asistidos en el Área de Salud de Ibiza y Formentera (ASEF), en el ámbito de la atención primaria. Participantes y métodos: Se incluyeron todos los pacientes afectados por la viruela del mono que cumplían con los criterios de inclusión (en total 79 pacientes), cubriendo el período comprendido entre el 1 junio y el 30 de noviembre de 2022. Se diseñó un protocolo asistencial para la captación de los pacientes, la toma de muestras, el rastreo de contactos, la notificación a las autoridades sanitarias, la asistencia clínica telefónica y la tramitación telemática de bajas y altas laborales. Resultados y conclusiones: La adhesión de los pacientes con el sistema de control fue mayoritaria. La telemedicina ha sido una herramienta muy útil para el intercambio de información durante la prestación de una atención médica continua a los pacientes afectados por el brote de infección por viruela símica, garantizando su seguridad y su intimidad y permitiendo el manejo de una enfermedad infecciosa que requiere aislamiento, control y seguimiento médico. Abstract: Objective: The objective of this work is to describe how the use of the information and communication technologies has been used in the clinical control, follow-up and treatment of all the patients affected by monkeypox in our health area. Design and site: A descriptive, observational and retrospective work has been carried out to show the clinical management of the monkeypox cases assisted in the Health Area of Ibiza and Formentera (ASEF), in the field of the primary care. Participants and methods: All patients affected by monkeypox who met the inclusion criteria were included in the study (a total of 79 patients), covering the period from 01/06/22 to 30/11/22. A protocol was designed in order to recruit the patients, extract the samples, monitor the close contacts, notify the cases to the health authorities, clinical assistance and administrative processing of the sick leaves. Results and conclusions: The adherence of the patients with the control system was majoritarian. Telemedicine has been a useful tool for the exchange of information during the provision of continuous medical care to patients affected by the outbreak of monkeypox infection, guaranteeing their safety and privacy and allowing the management of an infectious disease that requires isolation, control, and medical monitoring.
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- 2024
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82. ISO 50001-Based Energy Management Systems as a Practical Path for Decarbonization: Initial Findings from a Survey of Technical Assistance Cohort Participants
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Fuchs, Heidi, Therkelsen, Peter, Miller, William C, Siciliano, Graziella, and Sheaffer, Paul
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Engineering ,Built Environment and Design ,Physical Sciences ,Affordable and Clean Energy ,Climate Action ,energy management systems ,ISO 50001 ,decarbonization ,technical assistance ,organizational behavior ,Built environment and design ,Physical sciences - Abstract
Organizations face rising pressure to take action to reduce their climate-affecting emissions (i.e., decarbonize). While many responses are possible, an essential approach—strategically managing their energy consumption as an essential business practice via an ISO 50001-based energy management system—is not yet widely recognized as a framework for decarbonization. This study analyzes interim survey results from 24 organizations (a 48% response rate) implementing a rigorous energy management system, one deployed by the U.S. Department of Energy as “50001 Ready”, to test whether participating organizations perceive the energy management system under development as an essential aspect of their decarbonization efforts. The results are preliminary in nature, given the ongoing nature of the program and associated data collection; however, they are sufficient to refute our hypothesis that energy management systems are perceived by organizations participating in 50001 Ready cohorts to primarily affect energy performance with little-to-no connection regarding decarbonization efforts. Major findings include that participants’ decarbonization targets and commitments are driven by market imperatives (highlighting the importance of ISO 50001 as a management system tool) and that they see energy efficiency as vital to decarbonizing. We conclude by suggesting future research directions to further establish the premise that energy management systems are an effective, efficient, and long-lasting decarbonization strategy.
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- 2023
83. Encoding Concepts in Graph Neural Networks
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Magister, Lucie Charlotte, Barbiero, Pietro, Kazhdan, Dmitry, Siciliano, Federico, Ciravegna, Gabriele, Silvestri, Fabrizio, Jamnik, Mateja, and Lio, Pietro
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Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Computer Science - Logic in Computer Science - Abstract
The opaque reasoning of Graph Neural Networks induces a lack of human trust. Existing graph network explainers attempt to address this issue by providing post-hoc explanations, however, they fail to make the model itself more interpretable. To fill this gap, we introduce the Concept Encoder Module, the first differentiable concept-discovery approach for graph networks. The proposed approach makes graph networks explainable by design by first discovering graph concepts and then using these to solve the task. Our results demonstrate that this approach allows graph networks to: (i) attain model accuracy comparable with their equivalent vanilla versions, (ii) discover meaningful concepts that achieve high concept completeness and purity scores, (iii) provide high-quality concept-based logic explanations for their prediction, and (iv) support effective interventions at test time: these can increase human trust as well as significantly improve model performance.
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- 2022
84. Unveiling the role of cerebellar alterations in the autonomic nervous system: a systematic review of autonomic dysfunction in spinocerebellar ataxias
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Urbini, Nicole, Siciliano, Libera, Olivito, Giusy, and Leggio, Maria
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- 2023
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85. Identification and optimization of the operator’s hand and a haptic device dynamic, using artificial intelligence methods
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Mashayekhi, Ahmad, Mashayekhi, Mostafa, and Siciliano, Bruno
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- 2023
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86. On the structure of the Nehari set associated to a Schrödinger-Poisson system with prescribed mass: old and new results
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Siciliano, Gaetano and Silva, Kaye
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- 2023
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87. The rising role of cognitive reserve and associated compensatory brain networks in spinocerebellar ataxia type 2
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Siciliano, Libera, Olivito, Giusy, Urbini, Nicole, Silveri, Maria Caterina, and Leggio, Maria
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- 2023
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88. Boosted-oriented probabilistic smoothing-spline clustering of series
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Iorio, Carmela, Frasso, Gianluca, D’Ambrosio, Antonio, and Siciliano, Roberta
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- 2023
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89. ROX index as a predictor of failure of high-flow nasal cannula in infants with bronchiolitis
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Milena Siciliano Nascimento, Bianca Agostini Zólio, Luciana Assis Pires Andrade Vale, Patrícia Angelica de Lima Silva, Thereza Silva Souza, Louise Helena Rodrigues Gonçalves, Linus Pauling Fascina, and Cristiane do Prado
- Subjects
Medicine ,Science - Abstract
Abstract High-flow nasal cannula (HFNC) is a relatively recent therapy that has been used to treat respiratory failure. Until now, the criterion for failure requiring escalation to other forms of ventilatory support has remained unclear. This study evaluated how the ROX index predicts the success or failure of HFNC in infants with bronchiolitis. A prospective, observational, multicenter study was conducted in 2 pediatric ICUs. The data were collected at 7 moments. Patients were categorized into failure and success groups according to HFNC. A total of 102 infants were included, 18(17.6%) of whom failed HFNC therapy. For the ROX index, significant differences were observed between the failure 5.8(95%CI 4.7–7.1) and success 7.7(95%CI 7.2–8.2) groups (p = 0.005) at the 12 h evaluation. According to the analysis of the performance of the ROX index, the AUC at 12 h was 0.716(95%CI 0.591–0.842; p = 0.016). The best cutoff range for the ROX index at 12 h was 6.50–7.18, with a sensitivity of 42% and a specificity of 66% at the cutoff of 6.50, and a sensitivity of 92% and a specificity of 54% at the cutoff of 7.18. We concluded that the ROX index could be effective at predicting the failure of HFNC therapy in infants with bronchiolitis beginning at 12 h after installation.
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- 2024
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90. Verbal fluency patterns associated with the amnestic conversion from mild cognitive impairment to dementia
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Simona Cintoli, Laura Favilli, Riccardo Morganti, Gabriele Siciliano, Roberto Ceravolo, and Gloria Tognoni
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Medicine ,Science - Abstract
Abstract Patients with amnestic mild cognitive impairment (aMCI) are at a higher risk of converting to Alzheimer's disease. The aim of this study was to examine the potential use of Verbal Fluency (VF) measures as markers for predicting the conversion to dementia. At baseline, 61 aMCI, aged 65 to 80 years, underwent a comprehensive neuropsychological assessment, including phonemic (PVF) and semantic verbal fluency (SVF) tasks. After 18 months, 14 individuals with aMCI had progressed to a diagnosis of dementia. The findings revealed that aMCI-converter group had lower Mini Mental State Examination and Rey Auditory Verbal Learning Task scores than aMCI-no converter and produced fewer clusters in both VF tasks and a lower number of switches in PVF at baseline (p
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- 2024
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91. Existence and limit behavior of least energy solutions to constrained Schr\'odinger-Bopp-Podolsky systems in $\mathbb{R}^3$
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Ramos, Gustavo de Paula and Siciliano, Gaetano
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Mathematics - Analysis of PDEs ,35B38 - Abstract
Consider the following Schr\"odinger-Bopp-Podolsky system in $\mathbb{R}^3$ under an $L^2$-norm constraint, \[ \begin{cases} -\Delta u + \omega u + \phi u = u|u|^{p-2},\newline -\Delta \phi + a^2\Delta^2\phi=4\pi u^2,\newline \|u\|_{L^2}=\rho, \end{cases} \] where $a,\rho>0$ and our unknowns are $u,\phi\colon\mathbb{R}^3\to\mathbb{R}^3$ and $\omega\in\mathbb{R}$. We prove that if $2
0$ is sufficiently small (resp., sufficiently large), then this system admits a least energy solution. Moreover, we prove that if $2
0$ is sufficiently small, then least energy solutions are radially symmetric up to translation and as $a\to 0$, they converge to a least energy solution of the Schr\"odinger-Poisson-Slater system under the same $L^2$-norm constraint., Comment: 16 pages
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- 2022
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92. Reconstructing a generalized quadrangle from the Penttila-Williford $4-$class association scheme
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Monzillo, Giusy and Siciliano, Alessandro
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Mathematics - Combinatorics - Abstract
Penttila and Williford constructed a $4-$class association scheme from a generalized quadrangle with a doubly subtended subquadrangle. We show that an association scheme with appropriate parameters and satisfying some assumption about maximal cliques must be the Penttila-Williford scheme.
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- 2022
93. Classification of flocks of the quadratic cone in PG(3,64)
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Monzillo, Giusy, Penttila, Tim, and Siciliano, Alessandro
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Mathematics - Combinatorics - Abstract
Flocks are an important topic in the field of finite geometry, with many relations with other objects of interest. This paper is a contribution to the difficult problem of classifying flocks up to projective equivalence. We complete the classification of flocks of the quadratic cone in PG(3,q) for q <= 71, by showing by computer that there are exactly three flocks of the quadratic cone in PG(3,64), up to equivalence. The three flocks had previously been discovered, and they are the linear flock, the Subiaco flock and the Adelaide flock. The classification proceeds via the connection between flocks and herds of ovals in PG(2,q), q even, and uses the prior classification of hyperovals in PG(2,64).
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- 2022
94. A General Framework for Hierarchical Redundancy Resolution Under Arbitrary Constraints
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Fiore, Mario D., Meli, Gaetano, Ziese, Anton, Siciliano, Bruno, and Natale, Ciro
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Computer Science - Robotics - Abstract
The increasing interest in autonomous robots with a high number of degrees of freedom for industrial applications and service robotics demands control algorithms to handle multiple tasks as well as hard constraints efficiently. This paper presents a general framework in which both kinematic (velocity- or acceleration-based) and dynamic (torque-based) control of redundant robots are handled in a unified fashion. The framework allows for the specification of redundancy resolution problems featuring a hierarchy of arbitrary (equality and inequality) constraints, arbitrary weighting of the control effort in the cost function and an additional input used to optimize possibly remaining redundancy. To solve such problems, a generalization of the Saturation in the Null Space (SNS) algorithm is introduced, which extends the original method according to the features required by our general control framework. Variants of the developed algorithm are presented, which ensure both efficient computation and optimality of the solution. Experiments on a KUKA LBRiiwa robotic arm, as well as simulations with a highly redundant mobile manipulator are reported., Comment: Accepted to Transactions on Robotics (T-RO). Final version in preparaton. 20 pages, 19 figures
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- 2022
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95. ChatGPT: Friend or foe of patients with sleep-related breathing disorders?
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Alessia Martini, Simone Ielo, Mariarita Andreani, and Matteo Siciliano
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Artificial intelligence ,ChatGPT ,Sleep apnea ,OSAS ,Public Health ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
ChatGPT has played a prominent role in the media narrative on artificial intelligence over the past year. However, the potential applications of this popular chatbot have also been studied from a medical-health perspective. There are more than 600 papers published on this topic in 2023. The undisputed qualities of this form of AI, which is one of the deep-learning machines, are due to its ability to simulate conversation that is almost indistinguishable from that with another human being. We know how important communication is in medicine. That is why the many studies presented investigate ChatGPT's ability to answer public health questions or assist patients with certain diseases. We can say that communication is a therapeutic intervention, but can AI do it better than doctors?
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- 2024
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96. Air non-thermal plasma, a green approach for the treatment of contaminated water: the case of sulfamethoxazole
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Agata Giardina, Giusy Lofrano, Giovanni Libralato, Antonietta Siciliano, Ester Marotta, and Cristina Paradisi
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atmospheric plasma ,water treatment ,antibiotics ,ozone ,hydroxyl radical ,complete mineralization ,Environmental technology. Sanitary engineering ,TD1-1066 - Abstract
Non-thermal plasma (NTP) is gaining increasing attention as a promising approach for advanced water treatment to degrade persistent organic pollutants. Aqueous solutions of sulfamethoxazole (4-amino-N-(5-methylisoxazol-3-yl)-benzensulfonamide, SMZ), an antibiotic largely employed for humans and animals and a widespread persistent pollutant of waters and wastewaters, were subjected to air NTP treatment in a dielectric barrier discharge (DBD) reactor. The effects of SMZ initial concentration and of the solution pH on SMZ decomposition kinetics and transformation products were investigated. Efficient degradation was achieved, resulting in the complete removal of SMZ (10 μM initial concentration) in less than 25 min treatments, in the exhaustive mineralization (a result never reported before in plasma treatments and seldom reached also with other advanced oxidation processes) of all organic carbon in 6 h and in an energy efficiency of 6.4 g/kWh at 50% conversion. By means of HPLC-UV/Vis and LC-ESI-MSn analyses, a number of organic transformation products was identified along the path to SMZ mineralization, all present always in very small amounts and in turn decomposed at short treatment times. The effect of the solution pH on the genesis and decay of transformation products was also investigated. Based on comparisons with literature data and on previous findings obtained with the DBD reactor used in this work, it is concluded that the major reactive species involved in the degradation of SMZ are the hydroxyl radical and ozone. Finally, toxicological analyses of water initially containing 0.5 mM SMZ and subjected to 4 h NTP treatment showed that the by-products are not toxic to Raphidocelis subcapitata and Daphnia magna, while residual toxicity was detected by Aliivibrio fischeri.
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- 2024
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97. Predation of Boa constrictor (Squamata: Boidae) by Cerdocyon thous (Carnivora: Canidae) in a Caatinga biome region in the state of Piauí, northeastern Brazil
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Márcio Luiz Vargas Barbosa Filho, Rachel Ann Hauser Davis, and Salvatore Siciliano
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Brazil ,Caatinga Biome ,Crab-eating fox ,extreme climatic events ,risk-sensitive predation ,Zoology ,QL1-991 - Abstract
This study reports the predation on an adult common boa Boa constrictor specimen by the crab- eating fox Cerdocyon thous in the Caatinga Biome, a semi-arid Brazilian region. Such interactions represent cases of risk-sensitive predation, given the real possibility of crab-eating foxes being injured or killed when attacking adult common boa specimens. The likely role of extreme climatic events, such as the severe and prolonged drought that occurred in the region at the time of this record, in the occurrence of these trophic interactions between species is discussed. as entre especies.
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- 2024
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98. Unravelling the ecotoxicological impacts of gadolinium (Gd) on Mytilus galloprovincialis embryos and sperm in seawater: A preliminary study
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Marisa Spampinato, Antonietta Siciliano, Angela Travaglione, Teresa Chianese, Aldo Mileo, Giovanni Libralato, Marco Guida, Marco Trifuoggi, Vincenza De Gregorio, and Luigi Rosati
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Gadolinium ,Mussels ,Toxicity ,Reproduction ,Sperm motility ,Environmental pollution ,Science (General) ,Q1-390 ,Social sciences (General) ,H1-99 - Abstract
As the demand for rare earth elements (REEs) continues to surge in diverse industrial and medical domains, the ecological consequences of their ubiquitous presence have garnered heightened attention. Among the REEs, gadolinium (Gd), commonly used in medical imaging contrast agents, has emerged as a pivotal concern due to its inadvertent introduction into marine ecosystems via wastewater release. This study delves into the complex ecotoxicological implications of Gd contamination, focusing on its impact on the embryonic development and sperm functionality of Mytilus galloprovincialis. The findings from this study underscore the potential hazards posed by this rare element, offering a critical perspective on the ecological risks associated with Gd. Notably, this exploratory work reveals that Gd exerts a significant embryotoxic effect at elevated concentrations, with an observed half maximal effective concentration (EC50) value of 0.026 mg/L. Additionally, Gd exposure leads to a considerable reduction in sperm motility and alters sperm morfo-kinetic parameters, especially at a concentration of 5.6 mg/L. The results highlight a dose-dependent relationship between Gd exposure and the prevalence of specific malformation types in Mytilus embryos, further providing crucial insights into the potential risks imposed by this rare earth element.
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- 2024
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99. A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol [version 1; peer review: 2 approved]
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Terence W O'Neill, Robert Horne, Clare Jinks, Christian D Mallen, Zoe Paskins, Elaine Nicholls, Laurna Bullock, Stephanie Butler-Walley, Andrea Cherrington, Jane Fleming, Emma M Clark, Ida Bentley, Sarah Leyland, Cynthia P Iglesias-Urrutia, Simon Thomas, Jo Smith, David Webb, Sarah Lewis, Sarah Bathers, Michele Siciliano, Angela Clifford, Sarah Ryan, Joanne Protheroe, Nicky Dale, Janet Lefroy, Sarah Connacher, and Ashley Hawarden
- Subjects
Shared decision-making ,decision aid ,osteoporosis ,randomised controlled trial ,Fracture Liaison Service ,iFraP ,eng ,Medicine - Abstract
Background Good quality shared decision-making (SDM) conversations involve people with, or at risk of osteoporosis and clinicians collaborating to decide, where appropriate, which evidence-based medicines best fit the person’s life, beliefs, and values. We developed the improving uptake of Fracture Prevention drug treatments (iFraP) intervention comprising a computerised Decision Support Tool (DST), clinician training package and information resources, for use in UK Fracture Liaison Service consultations. Two primary objectives to determine (1) the effect of the iFraP intervention on patient-reported ease in decision-making about osteoporosis medicines, and (2) cost-effectiveness of iFraP intervention compared to usual NHS care. Secondary objectives are to determine the iFraP intervention effect on patient reported outcome and experience measures, clinical effectiveness (osteoporosis medicine adherence), and to explore intervention acceptability, mechanisms, and processes underlying observed effects, and intervention implementation. Methods The iFraP trial is a pragmatic, parallel-group, individual randomised controlled trial in patients referred to a Fracture Liaison Service, with nested mixed methods process evaluation and health economic analysis. Participants aged ≥50 years (n=380) are randomised (1:1 ratio) to one of two arms: (1) iFraP intervention (iFraP-i) or (2) comparator usual NHS care (iFraP-u) and are followed up at 2-weeks and 3-months. The primary outcome is ease of decision-making assessed 2 weeks after the consultation using the Decisional Conflict Scale (DCS). The primary objectives will be addressed by comparing the mean DCS score in each trial arm (using analysis of covariance) for patients given an osteoporosis medicine recommendation, alongside a within-trial cost-effectiveness and value of information (VoI) analysis. Process evaluation data collection includes consultation recordings, semi-structured interviews, and DST analytics. Discussion The iFraP trial will answer important questions about the effectiveness of the new ‘iFraP’ osteoporosis DST, coupled with clinician training, on SDM and informed initiation of osteoporosis medicines. Trial registration: ISRCTN 10606407, 21/11/2022 https://doi.org/10.1186/ISRCTN10606407
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- 2024
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100. Percepción del efecto de la pandemia en la salud y formación del estudiante de posgrado de pediatría en Uruguay
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Martin Notejane, Amalia Fernandes, Rosina Sanders, Mikaela De Agrela, Manuela Arce, Loreley García, Ana Inés Coimbra, Elena Vernazza, and Julio Siciliano
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educación médica ,posgrado de pediatría ,salud integral ,pandemia covid 19 ,uruguay ,Medicine ,Medicine (General) ,R5-920 - Abstract
Introducción: La pandemia impactó en la calidad de vida, salud integral y formación de los estudiantes de posgrados a nivel mundial. Objetivos: Describir la percepción del efecto de la pandemia en la salud integral y formación académica de estudiantes de posgrado de pediatría de Uruguay durante los años 2019- 2021. Metodología: Estudio descriptivo, transversal mediante encuesta a estudiantes de las generaciones 2019, 20 y 21. Se analizaron variables sociodemográficas y percepción del efecto de la pandemia en calidad de vida, salud, formación académica y rendimiento. Resultados: Participaron 93 estudiantes (65% de los habilitados). La mediana de edad fue 30,5 años, de género femenino: 88%. Cursaron la especialidad por residencia: 78,4%, en Montevideo 96%. El 41,3% expresó que cursar el posgrado durante la pandemia repercutió de forma negativa en su calidad de vida. Reportando reducción de actividades sociales: 83,3%, oferta laboral: 33,3%. Manifestaron sentirse agotados: 84%, fatigados: 64,4%. Se le diagnosticó una enfermedad nueva a 12,2% trastorno de ansiedad 5, depresión 4; reportaron consumo de psicofármacos durante la pandemia 13,3% versus 5,5% previo a esta. Consideraron que su formación se afectó negativamente: 57,3% y manifestaron afectación del rendimiento: 38,2%. Refirieron obstáculos en la participación de actividades virtuales: 94,3%, por superposición con otras actividades: 85,3%, o problemas de concentración: 22,4%. Conclusiones: Los encuestados reportaron efectos de la pandemia en su salud, sobre todo en el área psicoemocional, con repercusión en su calidad de vida. El efecto en la formación fue menor, identificándose puntos a mejorar, sobre todo evitar la superposición de actividades.
- Published
- 2024
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