1,157 results on '"Seyfried, Nicholas T"'
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52. Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity.
53. CT1812 biomarker signature from a meta‐analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease.
54. Exploring cortical proteins underlying the relation of neuroticism to cognitive resilience
55. Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level
56. Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases
57. Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq
58. Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50
59. Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid
60. Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging
61. Large- Scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity
62. Person‐specific differences in ubiquitin‐proteasome mediated proteostasis in human neurons
63. Network Analysis of the Cerebrospinal Fluid Proteome Reveals Shared and Unique Differences Between Sporadic and Familial Forms of Amyotrophic Lateral Sclerosis
64. A network approach reveals driver genes associated with survival of patients with triple-negative breast cancer
65. A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease
66. Brain proteome-wide association study implicates novel proteins in depression pathogenesis
67. Proteomic networks of gray and white matter reveal tissue‐specific changes in human tauopathy.
68. Psychosocial experiences are associated with human brain mitochondrial biology.
69. Proteomic analysis of Alzheimer's disease cerebrospinal fluid reveals alterations associated with APOE ε4 and atomoxetine treatment.
70. Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias
71. Heparin-enriched plasma proteome is significantly altered in Alzheimer’s Disease
72. Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD
73. Proximity labeling proteomics reveals Kv1.3 potassium channel immune interactors in microglia.
74. Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease
75. TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia
76. Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer’s Disease
77. Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer’s disease pathogenesis
78. Systems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tau
79. Experimental Validation of Bioinformatically Prioritized Therapeutic Hypotheses and Targets for Alzheimer’s Disease
80. Brain transcriptomic and proteomic analyses in an in vivo AD model further elucidate the role of the sigma‐2 receptor modulator CT1812 in Alzheimer’s disease
81. An Integrative Multi‐Omics Approach Reveals Molecular Signatures Associated with Age and High‐Fat Diet in Mouse Models of Alzheimer’s Disease
82. The tauopathy‐associated PERK variant, PERK‐B, induces maladaptive translation and reveals novel pathogenic mechanisms of PSP
83. In vivo TurboID proximity labeling to capture astrocyte proteomic and transcriptomic signatures under homeostatic and neuroinflammatory conditions
84. The SMOC1‐matrisomal proteomics network M42 controls brain homeostasis and modulates toxicity in fly Alzheimer’s Disease models
85. Transcriptomic and proteomic characterization of the locus coeruleus in a rat model of Alzheimer’s disease
86. The cytoskeletal protein Plectin regulates Tau‐induced neurotoxicity in Alzheimer’s Disease
87. A genetic and proteomic approach to understanding neuropsychiatric symptoms in ADRD
88. Immune regulatory roles for Kv1.3 channels in Microglia in Alzheimer’s Disease
89. Exploring the multimeric tau interactome and its convergence with human tauopathy
90. Genomic analysis of fibroblasts from marmosets carrying early‐onset Alzheimer’s disease mutations in PSEN1
91. Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis
92. Correction to: Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer’s disease
93. A proteomic network approach resolves stage-specific molecular phenotypes in chronic traumatic encephalopathy
94. Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue
95. EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair
96. Shared proteomic effects of cerebral atherosclerosis and Alzheimer’s disease on the human brain
97. Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
98. Lowering Hippocampal miR-29a Expression Slows Cognitive Decline and Reduces Beta-Amyloid Deposition in 5×FAD Mice
99. Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease
100. Global analysis of the heparin-enriched plasma proteome captures matrisome-associated proteins in Alzheimer’s disease
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