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54. Improved Clinical Outcome of COVID-19 in Hematologic Malignancy Patients Receiving a Fourth Dose of Anti-SARS-CoV-2 Vaccine: An EPICOVIDEHA Report

Author

Salmanton-García, Jon, primary, Marchesi, Francesco, additional, Glenthøj, Andreas, additional, Bilgin, Yavuz M., additional, van Praet, Jens, additional, Dávila-Valls, Julio, additional, Martín-Pérez, Sonia, additional, Labrador, Jorge, additional, van Doesum, Jaap, additional, Falces-Romero, Iker, additional, Farina, Francesca, additional, Schönlein, Martin, additional, Chanut, Mathilde, additional, Petzer, Verena, additional, Espigado, Ildefonso, additional, Dargenio, Michelina, additional, Aujayeb, Avinash, additional, Sili, Uluhan, additional, Serrano, Laura, additional, Pinczés, László Imre, additional, de Jonge, Nick, additional, Soto-Silva, Andrés, additional, Buquicchio, Caterina, additional, Prezioso, Lucia, additional, Marchetti, Monia, additional, Meers, Stef, additional, Busca, Alessandro, additional, Corradini, Paolo, additional, Hoenigl, Martin, additional, Koehler, Philipp, additional, Rahimli, Laman, additional, Çolak, Gökçe Melis, additional, Arellano, Elena, additional, Wolf, Dominik, additional, Gräfe, Stefanie, additional, Ammatuna, Emanuele, additional, Berg Venemyr, Caroline, additional, Cornely, Oliver A., additional, and Pagano, Livio, additional

Published
2022
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55. Monitoring the invasion of the aquatic bug Trichocorixa verticalis verticalis (Hemiptera: Corixidae) in the wetlands of Doñana National Park (SW Spain)

Author

Rodríguez-Pérez, Héctor, Florencio, Margarita, Gómez-Rodríguez, Carola, Green, Andy J., Díaz-Paniagua, Carmen, Serrano, Laura, Martens, K., editor, Oertli, Beat, editor, Céréghino, Régis, editor, Biggs, Jeremy, editor, Declerck, Steven, editor, Hull, Andrew, editor, and Miracle, Maria Rosa, editor

Published
2010
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58. Safety and Performance of a New Burr Hole Covering Device: Results of the Multicenter COVER Registry.

Author

Asencio-Cortés, Carlos, Villalba, Gloria, De Vilalta, Álex, Serrano, Laura, Álvarez-Holzapfel, María Jesús, Montes-Graciano, Guillermo, Málaga, Xavier, Muñoz-Hernandez, Fernando, and Gabarrós, Andreu

Subjects
PATIENT satisfaction, SATISFACTION, POLYETHER ether ketone, FOLLOW-up studies (Medicine), OPERATIVE surgery
Abstract

Background Burr hole covering in brain surgical procedures can avoid complications and unaesthetic results. The aim of this registry was to assess the safety and performance of a new polymeric burr hole covering device (Cranial COVER, NEOS Surgery). Methods A multicenter, prospective, clinical registry design was used for the study. All the patients who fulfilled the inclusion criteria were included in the study and followed up for 6 months. Baseline clinical parameters, surgical variables (technical success of the implantation, surgeon satisfaction), postoperative variables (aesthetic and functional results, neuroimaging artifacts), and adverse events were evaluated. Results Forty-three Cranial COVER devices were implanted in 30 patients. Most of them were implanted in frontal locations (53.5%). After implantation, 97.7% of the devices completely covered the burr hole, and 100% perfectly adapted to the skull surface. All surgeons ranked their satisfaction with the implantation procedure as very high or high. No artifacts were detected in any of the neuroimaging studies performed and no adverse events related with the device or its implantation were reported during the follow-up. There were significantly more scalp depressions associated with uncovered than with Cranial COVER–covered burr holes (p = 0.040). Patient satisfaction with covered burr holes located in the frontal and parietal areas was 9.0 ± 1.4 over 10. Conclusion Cranial COVER is a safe and reliable burr hole covering system that offers excellent cosmetic results and high satisfaction rates for both surgeons and patients. Cranial COVER is highly adaptable to the skull surface, and it was predominantly used in frontal locations due to their cosmetic importance. [ABSTRACT FROM AUTHOR]

Published
2023
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59. Persistence of Anti-S1 IgG against SARS-CoV-2 Eight Months after the Booster Dose of Vaccine in Naive and Previously Infected Healthcare Workers.

Author

Algarate, Sonia, Serrano, Laura, Bueno, Jessica, Herrero-Cortina, Beatriz, Alvarado, Elena, González-Barriga, María T., Ducons, María, Montero-Marco, Jesica, Arnal, Sara, Acha, Beatriz, Riesgo, María, Taboada, Ana, Sanz-Burillo, Pilar, Yuste, Cristina, and Benito, Rafael

Subjects
*MEDICAL personnel, *BOOSTER vaccines, *IMMUNOGLOBULIN G, *COVID-19 vaccines, *SARS-CoV-2, *IMMUNOGLOBULINS
Abstract

Our aim was to evaluate the immune response of healthcare workers included in the RIPOVAC study, after receiving a booster dose (third dose), in terms of intensity and persistence of induced antibodies. In the second phase of the RIPOVAC study, between December 2021 and January 2022, eight months after the second dose, 389 voluntary, immunocompetent, non-pregnant healthcare workers received a booster dose of SARS-CoV-2 vaccine, and a serum sample was obtained. Two groups of patients were established: with and without previous SARS-CoV-2 infection. In order to quantify anti-S1 IgG (AU/mL) we used CMIA (Abbott). All of the health workers were anti-S IgG positive 8 months after receiving the booster dose of the vaccine, with a mean of 17,040 AU/mL. In 53 patients without previous infection, antibody levels increased by a mean of 10,762 AU/mL. This figure is seven times higher than the one produced after the second dose (1506 AU/mL). The booster dose produces a robust elevation of the antibody level, which persists at 8 months, with levels significantly higher than those reached after the second dose, which allow one to predict a persistence of more than one year. The study demonstrates the efficacy of the booster dose of anti-SARS-CoV-2 vaccines. [ABSTRACT FROM AUTHOR]

Published
2023
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61. Assessment of humoral immune response to two mRNA SARS-CoV-2 vaccines (Moderna and Pfizer) in healthcare workers fully vaccinated with and without a history of previous infection

Author

Serrano, Laura, Algarate, Sonia, Herrero-Cortina, Beatriz, Bueno, Jessica, González-Barriga, Maria T., Ducons, Maria, Montero-Marco, Jesica, Acha, Beatriz, Taboada, Ana, Sanz-Burillo, Pilar, Yuste, Cristina, Benito, Rafael, and RIPOVAC, Study Group

Subjects
COVID-19 Vaccines, Post-vaccination, SARS-CoV-2, Health Personnel, Vaccination, COVID-19, General Medicine, Antibodies, Viral, Applied Microbiology and Biotechnology, Immunity, Humoral, Spain, Pfizer, Immunoglobulin G, Moderna, Spike Glycoprotein, Coronavirus, mRNA SARS-CoV- 2 vaccines, RIPOVAC, Humans, Healthcare workers, Immune response, Anti-S IgG SARS-CoV- 2, BNT162 Vaccine, Biotechnology, 2019-nCoV Vaccine mRNA-1273
Abstract

Aims Presence of anti-S1 region of SARS-CoV-2 spike protein was analysed, at two and eight months, in 477 immunocompetent healthcare workers in Zaragoza, Spain, vaccinated with mRNA-1273 (Moderna) or BNT162b2 (Pfizer). Methods and results Antibody analysis was performed with Alinity i System (Abbott). At 2 months, 100% of vaccinated had anti-S1 IgG (mean = 13,285 AU ml−1). This value was significantly higher with Moderna (18,192 AU ml−1) than with Pfizer (10,441 AU ml−1). The mean value of anti-S1 IgG after vaccination was significantly higher in patients with than without previous infection (18,539 vs. 7919 AU ml−1); in both groups was significantly higher with Moderna than with Pfizer (21,881 vs. 15,733 AU ml−1 and 11,949 vs. 6387 AU ml−1), respectively. At 8 months, 100% of patients were IgG positive, with higher levels with Moderna than with Pfizer. Nevertheless, in ensemble of cases, a mean decrease of antibody levels of 11,025 AU ml−1 was observed. Conclusion At 2 and 8 months after vaccination, IgG response persists with both vaccines but with important decrease which suggests the need for revaccination. Significance and impact of study The study contributes to know the immune status after vaccination with two of more used anti-SARS-CoV-2 vaccines. This knowledge is important for establishing the best vaccination strategy

Published
2022

65. Characterization of Pediatric Patients with Rheumatological Diseases Admitted to a Single Tertiary Health Hospital's Pediatric Intensive Care Unit in Latin America

Author

Erazo-Martínez, Valeria, additional, Ruiz-Ordoñez, Ingrid, additional, Álvarez, Carolina, additional, Serrano, Laura, additional, Aragón, Cristian C., additional, Tobón, Gabriel J., additional, Concha, Sandra, additional, Lasso, Rubén, additional, and Ramírez, Lyna-, additional

Published
2022
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67. Latin american cultural heritage in the community of madrid as a tourist asset

Author

Rubio Andrada, Luis, Vidal Serrano, Laura, Martínez Gutiérrez, Isabel, Novero Plaza, Raquel, Rubio Andrada, Luis, Vidal Serrano, Laura, Martínez Gutiérrez, Isabel, and Novero Plaza, Raquel

Abstract

The flow of people between different geographical areas of Latin America and the Madrid Region has taken place for centuries, bringing with it an exchange of tangible and intangible cultural elements. It has been usual to study the Spanish footprint in America; the novelty of this work is to visualise the heritage coming from the New World in Madrid in order to turn it into a tourist asset. Thus, places such as the Museum of America, the Statue of San Martín, the Botanical Garden, restaurants, and Latin dance venues, among others, are undoubtedly attractive. The approach to this work was to establish 10 tourist segments and then conduct two interviews with open-ended questions for each of them. A structured questionnaire of 47 closed- ended questions was designed with the responses of these twenty people. This questionnaire was answered in September 2021 by 481 people, which after filtering the answers was 456. After making a descriptive analysis of the results obtained, it is determined which elements should be considered in the different Latin American tourist routes in the Community of Madrid, how long they would last, how much they would be willing to pay, whether they would take them with a tour guide or not, at what time of the year or day of the week, what type of cultural elements they would prefer, etc. The results of this work will result in the design of a new cultural offer attractive to many tourists, which would complement the existing one, thus promoting an increase in the average stay, recurrence, and tourist expenditure in Madrid., El flujo de personas entre diversas áreas geográficas de Latinoamérica y la Región de Madrid se ha producido durante siglos, llevando aparejado un intercambio de elementos culturales tangibles e intangibles. Lo habitual ha sido estudiar la huella española en América; la novedad de este trabajo es la de visualizar el patrimonio proveniente del Nuevo Mundo en Madrid para convertirlo en un activo turístico. Así, lugares como el Museo de América, la Estatua de San Martín, el Jardín Botánico, restaurantes y lugares de baile latinos, entre otros, tienen indudable atractivo. La forma de abordar este trabajo ha sido estableciendo 10 segmentos de turistas, realizando a continuación dos entrevistas de preguntas abiertas para cada uno de ellos. Con las respuestas de esas veinte personas se diseñó un cuestionario estructurado de 47 preguntas cerradas. Dicho cuestionario fue respondido en septiembre de 2021 por 481 personas, que tras depurar las respuestas quedó en 456. Tras hacer un análisis descriptivo de los resultados obtenidos, se determinan qué elementos se deben considerar en las diversas rutas turísticas Latinoamericanas en la Comunidad de Madrid, qué duración tendrían, cuánto estarían dispuestos a pagar, si las realizarán con un guía turístico o no, en qué época del año o día de la semana, qué tipo de elementos culturales preferirían, etc. Los resultados de este trabajo tendrán como consecuencia el diseño de una nueva oferta cultural atractiva para muchos turistas, que completaría la ya existente, fomentando así el aumento de la estancia media, la recurrencia y el gasto turístico en Madrid.

Published
2022

68. Análisis y propuestas para impulsar la descarbonización en la industria minera

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Civil i Ambiental, Rodríguez Dono, Alfonso, Vargas Parra, María Violeta, León Serrano, Laura Ly, Universitat Politècnica de Catalunya. Departament d'Enginyeria Civil i Ambiental, Rodríguez Dono, Alfonso, Vargas Parra, María Violeta, and León Serrano, Laura Ly

Abstract

En el desarrollo de este trabajo se estudia la situación de la industria minera frente a la problemática medioambiental actual, por medio de una revisión extensa de la literatura de las que se incluyeron a lo largo del trabajo citas relevantes de informes, revistas y otros documentos de interés. Se identifican factores impulsores y alternativas que las empresas pueden implementar para la reducción de emisiones de CO2 y otras sustancias o para mitigar los daños producidos, tales como, mejoras en sus procesos, electrificación de vehículos y otras innovaciones de transporte, compensaciones y captura de carbono, o el uso de hidrógeno. También se identifican obstáculos técnicos, de experiencia y financiación que van a influir en la velocidad de la integración de tecnologías de descarbonización. Una vez hecho este trabajo de investigación, se seleccionan datos bibliográficos y analíticos de la producción de oro en la República Dominicana y por medio de la metodología de Análisis de Ciclo de Vida (ACV), utilizando el software SimaPro como herramienta, se evalúan las cargas del uso de combustibles fósiles en equipos móviles y electricidad en otros equipos de procesamiento de minerales. A partir del análisis realizado se plantean recomendaciones en forma de propuestas viables que ayuden la reducción del dióxido de carbono de las fuentes de energía, y, por tanto, a mitigar los impactos identificados. A su vez, se persigue que estas propuestas puedan servir de guía a otras empresas mineras, productores de energía independientes e instituciones de desarrollo sobre cómo acelerar la integración de las energías renovables en el sector minero., In the development of this work, the situation of the mining industry in the face of current environmental problems is studied by means of an extensive review of the literature, including relevant quotes from reports, journals and other documents of interest. Drivers and alternatives that companies can implement to reduce emissions of CO2 and other substances or to mitigate the damage produced are identified, such as improvements in their processes, electrification of vehicles and other transport innovations, carbon offsets and carbon capture, or the use of hydrogen. It also identifies technical, experience and funding barriers that will influence the speed of integration of decarbonization technologies. Once this research work is done, bibliographic and analytical data on gold production in the Dominican Republic is selected and by means of the Life Cycle Analysis (LCA) methodology, using SimaPro software as a tool, the burdens of the use of fossil fuels in mobile equipment and electricity in other mineral processing equipment are evaluated. Based on the analysis, recommendations are made in the form of viable proposals to help reduce carbon dioxide from energy sources and, therefore, mitigate the identified impacts. In turn, these proposals are intended to serve as a guide to other mining companies, independent power producers and development institutions on how to accelerate the integration of renewable energies in the mining sector.

Published
2022

69. Analysis of the methodology for the design of tourist routes on latin american heritage in the community of madrid

Author

Celemín Pedroche, Soledad, González Cavero, Ignacio, Vidal Serrano, Laura, Celemín Pedroche, Soledad, González Cavero, Ignacio, and Vidal Serrano, Laura

Abstract

The aim of this paper is to analyze the methodology carried out for the design of several tourist routes in the framework of the R&D Project America in Madrid. Interconnected heritages and tourist impact in the Community of Madrid. These routes will be subsequently implemented in several pilot experiences. Consequently, these routes can become a fundamental tool as a tourist attraction with the intention of contribute to the knowledge and dissemination of the Latin American legacy in the Madrid region. The interdisciplinary nature of the different working groups and collaborating entities, which participate in this project, give them a marked scientific and professional rigor. In order to achieve the main objective, a series of interviews have been carried out with different groups to analyze the tastes, preferences and interests when visiting the destination under study. This work is an analysis prior to a subsequent questionnaire conducted to the main segments of tourists, thus allowing us to adapt future and present routes with the intention of offering tourism adjusted to the demand and increasingly accessible and inclusive, El objetivo del presente artículoes abordar la metodología llevada a cabo para el diseño de varias rutas turísticas en el marco del Proyecto I+D “América en Madrid. Patrimonios interconectados e impacto turístico en la Comunidad de Madrid”, siendo implementadas posteriormente en varias experiencias piloto. De ahí que estos recorridos se conviertan en una herramienta fundamental como reclamo turístico que contribuyen al conocimiento y difusión del legado latinoamericano en la región madrileña, en cuya formulación la interdisciplinariedad de los diferentes grupos de trabajo y entidades colaboradoras que participan de este proyecto les otorga un marcado rigor científico y profesional. Para la consecución del objetivo principal se han realizado una serie de entrevistas a distintos colectivos con la finalidad de analizar los gustos, preferencias e intereses a la hora de visitar el destino objeto de estudio. Este trabajo supone un análisis previo a un posterior cuestionario realizado a los principales segmentos deturistas, permitiéndonos así adaptar futuras y presentes rutas con la intención de ofrecer un turismo ajustado a la demanda y cada vez más accesible e inclusivo

Published
2022

70. Improved Clinical Outcome of COVID-19 in Hematologic Malignancy Patients Receiving a Fourth Dose of Anti-SARS-CoV-2 Vaccine: An EPICOVIDEHA Report

Author

Salmanton-Garcia, Jon, Marchesi, Francesco, Glenthoj, Andreas, Bilgin, Yavuz M., van Praet, Jens, Davila-Valls, Julio, Martin-Perez, Sonia, Labrador, Jorge, van Doesum, Jaap, Falces-Romero, Iker, Farina, Francesca, Schoenlein, Martin, Chanut, Mathilde, Petzer, Verena, Espigado, Ildefonso, Dargenio, Michelina, Aujayeb, Avinash, Sili, Uluhan, Serrano, Laura, Pinczes, Laszlo Imre, de Jonge, Nick, Soto-Silva, Andres, Buquicchio, Caterina, Prezioso, Lucia, Marchetti, Monia, Meers, Stef, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Rahimli, Laman, Colak, Gokce Melis, Arellano, Elena, Wolf, Dominik, Graefe, Stefanie, Ammatuna, Emanuele, Venemyr, Caroline Berg, Cornely, Oliver A., Pagano, Livio, Salmanton-Garcia, Jon, Marchesi, Francesco, Glenthoj, Andreas, Bilgin, Yavuz M., van Praet, Jens, Davila-Valls, Julio, Martin-Perez, Sonia, Labrador, Jorge, van Doesum, Jaap, Falces-Romero, Iker, Farina, Francesca, Schoenlein, Martin, Chanut, Mathilde, Petzer, Verena, Espigado, Ildefonso, Dargenio, Michelina, Aujayeb, Avinash, Sili, Uluhan, Serrano, Laura, Pinczes, Laszlo Imre, de Jonge, Nick, Soto-Silva, Andres, Buquicchio, Caterina, Prezioso, Lucia, Marchetti, Monia, Meers, Stef, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Rahimli, Laman, Colak, Gokce Melis, Arellano, Elena, Wolf, Dominik, Graefe, Stefanie, Ammatuna, Emanuele, Venemyr, Caroline Berg, Cornely, Oliver A., and Pagano, Livio

Published
2022

71. COVID-19 in vaccinated adult patients with hematological malignancies: preliminary results from EPICOVIDEHA

Author

Pagano, Livio, Salmanton-Garc, Jon, Marchesi, Francesco, Lopez-Garcia, Alberto, Lamure, Sylvain, Itri, Federico, Gomes-Silva, Maria, Dragonetti, Giulia, Falces-Romero, Iker, van Doesum, Jaap, Sili, Uluhan, Labrador, Jorge, Calbacho, Maria, Bilgin, Yavuz M., Weinbergerova, Barbora, Serrano, Laura, Susana, Jose-Maria Ribera-Santa, Malak, Sandra, Loureiro-Amigo, Jose, Glenthoj, Andreas, Cordoba-Mascunano, Raul, Nunes-Rodrigues, Raquel, Gonzalez-Lopez, Tomas-Jose, Karlsson, Linda Katharina, Jimenez-Lorenzo, Maria-Josefa, Hernandez-Rivas, Jose-Angel, Jaksic, Ozren, Racil, Zdenek, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Klimko, Nikolai, Koehler, Philipp, Pagliuca, Antonio, Passamonti, Francesco, Cornely, Oliver A., Pagano, Livio, Salmanton-Garc, Jon, Marchesi, Francesco, Lopez-Garcia, Alberto, Lamure, Sylvain, Itri, Federico, Gomes-Silva, Maria, Dragonetti, Giulia, Falces-Romero, Iker, van Doesum, Jaap, Sili, Uluhan, Labrador, Jorge, Calbacho, Maria, Bilgin, Yavuz M., Weinbergerova, Barbora, Serrano, Laura, Susana, Jose-Maria Ribera-Santa, Malak, Sandra, Loureiro-Amigo, Jose, Glenthoj, Andreas, Cordoba-Mascunano, Raul, Nunes-Rodrigues, Raquel, Gonzalez-Lopez, Tomas-Jose, Karlsson, Linda Katharina, Jimenez-Lorenzo, Maria-Josefa, Hernandez-Rivas, Jose-Angel, Jaksic, Ozren, Racil, Zdenek, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Klimko, Nikolai, Koehler, Philipp, Pagliuca, Antonio, Passamonti, Francesco, and Cornely, Oliver A.

Published
2022

72. Outcome of infection with omicron SARS-CoV-2 variant in patients with hematological malignancies: An EPICOVIDEHA survey report

Author

Blennow, Ola, Salmanton-Garcia, Jon, Nowak, Piotr, Itri, Federico, Van Doesum, Jaap, Lopez-Garcia, Alberto, Farina, Francesca, Jaksic, Ozren, Pinczes, Laszlo Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jimenez, Moraima, Ormazabal-Velez, Irati, Weinbergerova, Barbora, Dulery, Remy, Stojanoski, Zlate, Lahmer, Tobias, Fernandez, Noemi, Hernandez-Rivas, Jose-angel, Petzer, Verena, De Jonge, Nick, Glenthoj, Andreas, De Ramon, Cristina, Biernat, Monika M., Fracchiolla, Nicola, Aujayeb, Avinash, Van Praet, Jens, Schonlein, Martin, Mendez, Gustavo-Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciume, Mariarita, Ammatuna, Emanuele, Cordoba, Raul, Garcia-Pouton, Nicole, Graefe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, Garcia-Sanz, Ramon, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, De Kort, Elizabeth, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, Garcia-Vidal, Carolina, Dargenio, Michelina, Danion, Francois, Machado, Marina, Bailen-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Chai, Louis Yi Ann, Kho, Chi Shan, Bonanni, Matteo, Lievin, Raphael, Marchesi, Francesco, Cornely, Oliver A., Pagano, Livio, Blennow, Ola, Salmanton-Garcia, Jon, Nowak, Piotr, Itri, Federico, Van Doesum, Jaap, Lopez-Garcia, Alberto, Farina, Francesca, Jaksic, Ozren, Pinczes, Laszlo Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jimenez, Moraima, Ormazabal-Velez, Irati, Weinbergerova, Barbora, Dulery, Remy, Stojanoski, Zlate, Lahmer, Tobias, Fernandez, Noemi, Hernandez-Rivas, Jose-angel, Petzer, Verena, De Jonge, Nick, Glenthoj, Andreas, De Ramon, Cristina, Biernat, Monika M., Fracchiolla, Nicola, Aujayeb, Avinash, Van Praet, Jens, Schonlein, Martin, Mendez, Gustavo-Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciume, Mariarita, Ammatuna, Emanuele, Cordoba, Raul, Garcia-Pouton, Nicole, Graefe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, Garcia-Sanz, Ramon, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, De Kort, Elizabeth, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, Garcia-Vidal, Carolina, Dargenio, Michelina, Danion, Francois, Machado, Marina, Bailen-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Chai, Louis Yi Ann, Kho, Chi Shan, Bonanni, Matteo, Lievin, Raphael, Marchesi, Francesco, Cornely, Oliver A., and Pagano, Livio

Published
2022

73. Improved Clinical Outcome of COVID-19 in Hematologic Malignancy Patients Receiving a Fourth Dose of Anti-SARS-CoV-2 Vaccine: An EPICOVIDEHA Report

Author

Gilead Sciences, Salmanton-García, Jon, Marchesi, Francesco, Glenthøj, Andrea, Bilgin, Yavuz M., Praet, Jens van, Dávila, Julio, Martín-Pérez, Sonia, Labrador, Jorge, Doesum, Jaap van, Falces-Romero, Iker, Farina, Francesca, Schönlein, Martin, Chanut, Mathilde, Petzer, Verena, Espigado, Ildefonso, Dargenio, Michelina, Aujayeb, Avinash, Sili, Uluhan, Serrano, Laura, Pinczés, László Imre, Jonge, Nick de, Soto-Silva, Andrés, Buquicchio, Caterina, Prezioso, Lucia, Marchetti, Monia, Meers, Stef, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Rahimli, Laman, Çolak, Gökçe Melis, Arellano-Orden, Elena, Wolf, Dominik, Gräfe, Stefanie, Ammatuna, Emanuele, Berg Venemyr, Caroline, Cornely, Oliver A., Pagano, Livio, Gilead Sciences, Salmanton-García, Jon, Marchesi, Francesco, Glenthøj, Andrea, Bilgin, Yavuz M., Praet, Jens van, Dávila, Julio, Martín-Pérez, Sonia, Labrador, Jorge, Doesum, Jaap van, Falces-Romero, Iker, Farina, Francesca, Schönlein, Martin, Chanut, Mathilde, Petzer, Verena, Espigado, Ildefonso, Dargenio, Michelina, Aujayeb, Avinash, Sili, Uluhan, Serrano, Laura, Pinczés, László Imre, Jonge, Nick de, Soto-Silva, Andrés, Buquicchio, Caterina, Prezioso, Lucia, Marchetti, Monia, Meers, Stef, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Rahimli, Laman, Çolak, Gökçe Melis, Arellano-Orden, Elena, Wolf, Dominik, Gräfe, Stefanie, Ammatuna, Emanuele, Berg Venemyr, Caroline, Cornely, Oliver A., and Pagano, Livio

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes life-threatening COVID-19 in hematologic malignancy (HM) patients, associated with high morbidity and mortality in this particularly vulnerable population.1 After more than 2 years since the beginning of the COVID-19 pandemic, several prophylactic and therapeutic strategies have been developed against SARS-CoV-2, including targeted antivirals, monoclonal antibodies and vaccines, leading to improved prognosis in HM patients.2 Our preliminary data in vaccinated HM patients with COVID-19 reported a significant reduction in disease severity and mortality rate, however, still exceeding the mortality rate in the overall population

Published
2022

74. Outcome of infection with omicron SARS-CoV-2 variant in patients with hematological malignancies: An EPICOVIDEHA survey report

Author

Gilead Sciences, Blennow, Ola, Salmanton-García, Jon, Nowak, Piotr, Itri, Federico, Doesum, Jaap van, López-García, Alberto, Farina, Francesca, Jakšić, Ozren, Pinczés, László Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jiménez, Moraima, Ormazabal-Vélez, Irati, Weinbergerová, Barbora, Duléry, Rémy, Stojanoski, Zlate, Lahmer, Tobias, Fernández, Noemí, Hernández-Rivas, José Ángel, Petzer, Verena, Jonge, Nick de, Glenthøj, Andrea, Ramón, Cristina de, Biernat, Monika, Fracchiolla, Nicola S., Aujayeb, Avinash, Praet, Jens van, Schönlein, Martin, Méndez, Gustavo-Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciumè, Mariarita, Ammatuna, Emanuele, Córdoba, Raúl, García-Poutón, Nicole, Gräfe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, García-Sanz, Ramón, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, Kort, Elizabeth De, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, García-Vidal, Carolina, Dargenio, Michelina, Danion, François, Machado, Marina, Bailén-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Yi Ann Chai, Louis, Shan Kho, Chi, Bonanni, Matteo, Lievin, Raphaël, Marchesi, Francesco, Cornely, Oliver A., Pagano, Livio, Gilead Sciences, Blennow, Ola, Salmanton-García, Jon, Nowak, Piotr, Itri, Federico, Doesum, Jaap van, López-García, Alberto, Farina, Francesca, Jakšić, Ozren, Pinczés, László Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jiménez, Moraima, Ormazabal-Vélez, Irati, Weinbergerová, Barbora, Duléry, Rémy, Stojanoski, Zlate, Lahmer, Tobias, Fernández, Noemí, Hernández-Rivas, José Ángel, Petzer, Verena, Jonge, Nick de, Glenthøj, Andrea, Ramón, Cristina de, Biernat, Monika, Fracchiolla, Nicola S., Aujayeb, Avinash, Praet, Jens van, Schönlein, Martin, Méndez, Gustavo-Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciumè, Mariarita, Ammatuna, Emanuele, Córdoba, Raúl, García-Poutón, Nicole, Gräfe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, García-Sanz, Ramón, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, Kort, Elizabeth De, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, García-Vidal, Carolina, Dargenio, Michelina, Danion, François, Machado, Marina, Bailén-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Yi Ann Chai, Louis, Shan Kho, Chi, Bonanni, Matteo, Lievin, Raphaël, Marchesi, Francesco, Cornely, Oliver A., and Pagano, Livio

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused high mortality in patients with hematological malignancies (HM).1 The newly emerged omicron variants of SARS-CoV-2 harbor multiple novel spike protein mutations that raise concerns about vaccine efficiency and antiviral efficacy of the available therapeutic monoclonal antibodies.2 The first published clinical data in immunocompetent patients have found that infection with omicron variants is associated with reduced vaccine efficiency compared to the delta variants, but decreased hospital admission and mortality.3, 4 Preliminary, prepublished, data from a large case–control study have shown that the vaccine effect against omicron in immunocompromised patients, including HM patients, is even more reduced, but data regarding clinical outcomes are lacking.5 The aim of this study was to describe risk factors, antiviral treatment and outcomes of SARS-CoV-2 omicron variant infection in 593 HM patients included in the EPICOVIDEHA registry.

Published
2022

75. Improved Clinical Outcome of COVID-19 in Hematologic Malignancy Patients Receiving a Fourth Dose of Anti-SARS-CoV-2 Vaccine:An EPICOVIDEHA Report

Author

Salmanton-García, Jon, Marchesi, Francesco, Glenthøj, Andreas, Bilgin, Yavuz M., Van Praet, Jens, Dávila-Valls, Julio, Martín-Pérez, Sonia, Labrador, Jorge, Van Doesum, Jaap, Falces-Romero, Iker, Farina, Francesca, Schönlein, Martin, Chanut, Mathilde, Petzer, Verena, Espigado, Ildefonso, Dargenio, Michelina, Aujayeb, Avinash, Sili, Uluhan, Serrano, Laura, Pinczés, László Imre, De Jonge, Nick, Soto-Silva, Andrés, Buquicchio, Caterina, Prezioso, Lucia, Marchetti, Monia, Meers, Stef, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Rahimli, Laman, Çolak, Gökçe Melis, Arellano, Elena, Wolf, Dominik, Gräfe, Stefanie, Ammatuna, Emanuele, Berg Venemyr, Caroline, Cornely, Oliver A., Pagano, Livio, Salmanton-García, Jon, Marchesi, Francesco, Glenthøj, Andreas, Bilgin, Yavuz M., Van Praet, Jens, Dávila-Valls, Julio, Martín-Pérez, Sonia, Labrador, Jorge, Van Doesum, Jaap, Falces-Romero, Iker, Farina, Francesca, Schönlein, Martin, Chanut, Mathilde, Petzer, Verena, Espigado, Ildefonso, Dargenio, Michelina, Aujayeb, Avinash, Sili, Uluhan, Serrano, Laura, Pinczés, László Imre, De Jonge, Nick, Soto-Silva, Andrés, Buquicchio, Caterina, Prezioso, Lucia, Marchetti, Monia, Meers, Stef, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Rahimli, Laman, Çolak, Gökçe Melis, Arellano, Elena, Wolf, Dominik, Gräfe, Stefanie, Ammatuna, Emanuele, Berg Venemyr, Caroline, Cornely, Oliver A., and Pagano, Livio

Published
2022

76. Outcome of infection with omicron SARS-CoV-2 variant in patients with hematological malignancies:An EPICOVIDEHA survey report

Author

Blennow, Ola, Salmanton-García, Jon, Nowak, Piotr, Itri, Federico, Van Doesum, Jaap, López-García, Alberto, Farina, Francesca, Jaksic, Ozren, Pinczés, László Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jiménez, Moraima, Ormazabal-Vélez, Irati, Weinbergerová, Barbora, Duléry, Rémy, Stojanoski, Zlate, Lahmer, Tobias, Fernández, Noemí, Hernández-Rivas, José Ángel, Petzer, Verena, De Jonge, Nick, Glenthøj, Andreas, De Ramón, Cristina, Biernat, Monika M., Fracchiolla, Nicola, Aujayeb, Avinash, Van Praet, Jens, Schönlein, Martin, Méndez, Gustavo Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciumè, Mariarita, Ammatuna, Emanuele, Cordoba, Raul, García-Poutón, Nicole, Gräfe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, García-Sanz, Ramón, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, De Kort, Elizabeth, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, Garcia-Vidal, Carolina, Dargenio, Michelina, Danion, François, Machado, Marina, Bailén-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Chai, Louis Yi Ann, Kho, Chi Shan, Bonanni, Matteo, Liévin, Raphaël, Marchesi, Francesco, Cornely, Oliver A., Pagano, Livio, Blennow, Ola, Salmanton-García, Jon, Nowak, Piotr, Itri, Federico, Van Doesum, Jaap, López-García, Alberto, Farina, Francesca, Jaksic, Ozren, Pinczés, László Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jiménez, Moraima, Ormazabal-Vélez, Irati, Weinbergerová, Barbora, Duléry, Rémy, Stojanoski, Zlate, Lahmer, Tobias, Fernández, Noemí, Hernández-Rivas, José Ángel, Petzer, Verena, De Jonge, Nick, Glenthøj, Andreas, De Ramón, Cristina, Biernat, Monika M., Fracchiolla, Nicola, Aujayeb, Avinash, Van Praet, Jens, Schönlein, Martin, Méndez, Gustavo Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciumè, Mariarita, Ammatuna, Emanuele, Cordoba, Raul, García-Poutón, Nicole, Gräfe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, García-Sanz, Ramón, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, De Kort, Elizabeth, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, Garcia-Vidal, Carolina, Dargenio, Michelina, Danion, François, Machado, Marina, Bailén-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Chai, Louis Yi Ann, Kho, Chi Shan, Bonanni, Matteo, Liévin, Raphaël, Marchesi, Francesco, Cornely, Oliver A., and Pagano, Livio

Published
2022

77. COVID-19 in vaccinated adult patients with hematological malignancies:preliminary results from EPICOVIDEHA

Author

Pagano, Livio, Salmanton-García, Jon, Marchesi, Francesco, López-García, Alberto, Lamure, Sylvain, Itri, Federico, Gomes-Silva, Maria, Dragonetti, Giulia, Falces-Romero, Iker, van Doesum, Jaap, Sili, Uluhan, Labrador, Jorge, Calbacho, Maria, Bilgin, Yavuz M., Weinbergerová, Barbora, Serrano, Laura, Ribera-Santa Susana, José María, Malak, Sandra, Loureiro-Amigo, José, Glenthøj, Andreas, Córdoba-Mascuñano, Raúl, Nunes-Rodrigues, Raquel, González-López, Tomás José, Karlsson, Linda Katharina, Jiménez-Lorenzo, María Josefa, Hernández-Rivas, José Ángel, Jaksic, Ozren, Ráčil, Zdeněk, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Klimko, Nikolai, Koehler, Philipp, Pagliuca, Antonio, Passamonti, Francesco, Cornely, Oliver A., Pagano, Livio, Salmanton-García, Jon, Marchesi, Francesco, López-García, Alberto, Lamure, Sylvain, Itri, Federico, Gomes-Silva, Maria, Dragonetti, Giulia, Falces-Romero, Iker, van Doesum, Jaap, Sili, Uluhan, Labrador, Jorge, Calbacho, Maria, Bilgin, Yavuz M., Weinbergerová, Barbora, Serrano, Laura, Ribera-Santa Susana, José María, Malak, Sandra, Loureiro-Amigo, José, Glenthøj, Andreas, Córdoba-Mascuñano, Raúl, Nunes-Rodrigues, Raquel, González-López, Tomás José, Karlsson, Linda Katharina, Jiménez-Lorenzo, María Josefa, Hernández-Rivas, José Ángel, Jaksic, Ozren, Ráčil, Zdeněk, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Klimko, Nikolai, Koehler, Philipp, Pagliuca, Antonio, Passamonti, Francesco, and Cornely, Oliver A.

Published
2022

78. Presence of Bisphenol A and Parabens in a Neonatal Intensive Care Unit: An Exploratory Study of Potential Sources of Exposure

Author

Iribarne-Duran, Luz M., Artacho-Cordon, Francisco, Pena-Caballero, Manuela, Molina-Molina, Jose M., Jimenez-Diaz, Inmaculada, Vela-Soria, Fernando, Serrano, Laura, Hurtado, Jose A., Fernandez, Mariana F., Freire, Carmen, and Olea, Nicolas

Subjects
Bisphenol-A, Newborn infants, Leaching, Estrogens, Neonatal intensive care, Phenols (Class of compounds), Medical supplies, Hormones, Phototherapy, Sex hormones, Luciferase, Estradiol, Backup software, Environmental issues, Health, European Union
Abstract

Background: Newborns in neonatal intensive care units (NICUs) are in contact with a variety of medical products whose production might include synthetic chemicals with hormonal activity. Objectives: Our aim was to assess the content of bisphenol A (BPA) and parabens (PBs) and the hormone-like activities of a subset of medical products commonly used in NICUs in prolonged intimate contact with NICU newborns. Methods: Fifty-two NICU items were analyzed, determining the concentrations of BPA and PBs [methyl- (MeP), ethyl- (EtP), propyl- (PrP), and butylparaben (BuP)] and using the E-Screen and PALM-luciferase assays to measure the in vitro (anti-)estrogenic and (anti-)androgenic activity, respectively, of the extracts. Items found to have elevated BPA/PB content or hormone-like activities were further extracted using leaching methodologies. Results: BPA was found in three-fifths and PBs in four-fifths of tested NICU items, and ~ 25% and ~ 10% of extracts evidenced estrogenic and anti-androgenic activity, respectively. The highest BPA content was found in the three-way stopcock (>7.000 ng/g), followed by patterned transparent film dressing, gastro-duodenal feeding tubes, sterile gloves, single-lumen umbilical catheters, and intravenous (IV) infusion extension sets (concentrations ranged from 100 to 700ng/g BPA). A total PB concentration [SIGMA] PBs) >100ng/g was observed in several items, including light therapy protection glasses, patterned transparent film dressing, winged IV catheters, IV infusion extension sets, and textile tape. The highest estrogenic activity [>450 [micro]M estradiol equivalent ([E.sub.2]eq)] was found in small dummy nipples, three-way stopcocks, and patterned transparent film dressing and the highest anti-androgenic activity [>5 mM procymidone equivalent units per gram (Proceq/g)] in small dummy nipples and three-way stopcocks. Discussion: According to these findings, neonates might be exposed to multiple sources of BPA and PBs in NICUs via inhalation, dermal, oral, and IV/parenteral routes. There is a need to address the future health implications for these extremely vulnerable patients and to adopt precautionary preventive measures as a matter of urgency. https://doi.org/10.1289/EHP5564, Introduction Bisphenol A (BPA) is a high-production volume chemical commonly used in the manufacturing of epoxy resins and polycarbonate plastics and as an additive in many other plastics, for example, [...]

Published
2019
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81. Developing a New Vegetation Index Using Cyan, Orange, and Near Infrared Bands to Analyze Soybean Growth Dynamics.

Author

Vásquez, Roger A. Rojas, Heenkenda, Muditha K., Nelson, Reg, and Segura Serrano, Laura

Subjects
LEAF area index, SOYBEAN, GROUND vegetation cover, AGRICULTURAL research, REMOTE sensing, ORANGES
Abstract

Remote sensing Vegetation Indices (VIs) are simple, effective, and widely used methods for quantitative and qualitative analysis of vegetation cover, vigor, and growth dynamics. This study developed and assessed a new vegetation index (VI) using Cyan, Orange, and Near Infrared (NIR) bands to assess Soybean growth dynamics. The study was conducted at Lakehead University Agriculture Research Station, Thunder Bay, Canada, over four reproductive stages of Soybean growth (R4–R7). Spectral profiles were created for each stage, and the correlation between each spectral band at different stages was tested. There was no linear correlation between different bands except the correlation between the Cyan and Orange bands at R5 and R6 stages. Existing VIs have also been explored using approximately similar band combinations. Based on this analysis, three VIs were proposed for this new camera, and their behavior at different stages was evaluated using Leaf Area Index (LAI). Cyan and Orange spectral values were relatively high in the first and last growing seasons, while NIR values increased dramatically in the mid-growing seasons and decreased in the last stage. VINIR,O,C index showed the best results for mid-growing seasons (correlation with LAI = 0.39 for R5 and R6). VIC,O index showed a high level of details visually (leaves and background) for R4 and R7 than the other indices and correlated highly with LAI (0.48 and −0.5, respectively). Overall, the study provided new VIs that can be used to effectively analyze Soybean growth dynamics, with different VIs showing reliability over different growing stages. [ABSTRACT FROM AUTHOR]

Published
2023
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83. Outcome of infection with omicron SARS‐CoV ‐2 variant in patients with hematological malignancies: An EPICOVIDEHA survey report

Author

Blennow, Ola, primary, Salmanton‐García, Jon, additional, Nowak, Piotr, additional, Itri, Federico, additional, Van Doesum, Jaap, additional, López‐García, Alberto, additional, Farina, Francesca, additional, Jaksic, Ozren, additional, Pinczés, László Imre, additional, Bilgin, Yavuz M., additional, Falces‐Romero, Iker, additional, Jiménez, Moraima, additional, Ormazabal‐Vélez, Irati, additional, Weinbergerová, Barbora, additional, Duléry, Rémy, additional, Stojanoski, Zlate, additional, Lahmer, Tobias, additional, Fernández, Noemí, additional, Hernández‐Rivas, José‐Ángel, additional, Petzer, Verena, additional, De Jonge, Nick, additional, Glenthøj, Andreas, additional, De Ramón, Cristina, additional, Biernat, Monika M., additional, Fracchiolla, Nicola, additional, Aujayeb, Avinash, additional, Van Praet, Jens, additional, Schönlein, Martin, additional, Méndez, Gustavo‐Adolfo, additional, Cattaneo, Chiara, additional, Guidetti, Anna, additional, Sciumè, Mariarita, additional, Ammatuna, Emanuele, additional, Cordoba, Raul, additional, García‐Poutón, Nicole, additional, Gräfe, Stefanie, additional, Cabirta, Alba, additional, Wolf, Dominik, additional, Nordlander, Anna, additional, García‐Sanz, Ramón, additional, Delia, Mario, additional, Berg Venemyr, Caroline, additional, Brones, Clara, additional, Di Blasi, Roberta, additional, De Kort, Elizabeth, additional, Meers, Stef, additional, Lamure, Sylvain, additional, Serrano, Laura, additional, Merelli, Maria, additional, Coppola, Nicola, additional, Bergantim, Rui, additional, Besson, Caroline, additional, Kohn, Milena, additional, Petiti, Jessica, additional, Garcia‐Vidal, Carolina, additional, Dargenio, Michelina, additional, Danion, François, additional, Machado, Marina, additional, Bailén‐Almorox, Rebeca, additional, Hoenigl, Martin, additional, Dragonetti, Giulia, additional, Chai, Louis Yi Ann, additional, Kho, Chi Shan, additional, Bonanni, Matteo, additional, Liévin, Raphaël, additional, Marchesi, Francesco, additional, Cornely, Oliver A., additional, and Pagano, Livio, additional

Published
2022
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89. La orden de detención europea

Author

Estévez Serrano, Laura De Las Nieves, Martinón Quintero, Ruth, and Grado En Derecho

Subjects
Principio de doble incriminación, Principio de reconocimiento mutuo, Cooperación judicial, Detención y entrega europea
Abstract

The European arrest warrant is an instrument of judicial cooperation between the Member States of the European Union for the arrest and surrender of persons suspected of having committed a criminal offence. This system represented a change in the body of European law, leaving behind the extradition system that had been used in the European Union for years. The novelty introduced by the EAW was mainly the principle of mutual recognition of judicial decisions by the EU Member States, which directly incorporated the judicial decisions of other states, as well as the exception to the principle of double criminality that had been used in the extradition system. This exception is given by the recognition of a list of 32 offences that are exempt from dual criminality. The European arrest warrant came into force in 2004 and, since then, it has been the instrument most widely used by the Member States to create the area of freedom, justice and security that the EU had been seeking. La orden de detención y entrega europea (ODE) es un instrumento de cooperación judicial entre los Estados miembros de la Unión Europea para la detención y entrega de personas presuntas autoras de un hecho delictivo. Este sistema supuso un cambio en la masa normativa europea, al dejar atrás al sistema de extradición que se venía utilizando en la Unión Europea durante años. La novedad que introdujo la ODE fue principalmente el principio de reconocimiento mutuo de las resoluciones judiciales por parte de los Estados miembros de la UE que incorporaban directamente las resoluciones judiciales de otros Estados, así como, la excepción al principio de la doble incriminación que se venía utilizando en el sistema extradicional. Dicha excepción viene dada por el reconocimiento de un listado de 32 delitos que quedaban exentos de la doble incriminación. La ODE entró en vigor en el año 2004 y, desde entonces, ha sido el instrumento más utilizado por parte de los Estados miembros al generar ese espacio de libertad, justicia y seguridad que venía buscando la UE.

Published
2022

91. Outcome of infection with omicron <scp>SARS‐ CoV</scp> ‐2 variant in patients with

Author

Blennow, Ola, Salmanton‐García, Jon, Nowak, Piotr, Itri, Federico, Van Doesum, Jaap, López‐ García, Alberto, Farina, Francesca, Jaksic, Ozren, Pinczés, László Imre, Bilgin, Yavuz M., Falces‐Romero, Iker, Jiménez, Moraima, Ormazabal‐Vélez, Irati, Weinbergerová, Barbora, Duléry, Rémy, Stojanoski, Zlate, Lahmer, Tobias, Fernández, Noemí, Hernández‐Rivas, José‐Ángel, Petzer, Verena, De Jonge, Nick, Glenthøj, Andreas, De Ramón, Cristina, Biernat, Monika M., Fracchiolla, Nicola, Aujayeb, Avinash, Van Praet, Jens, Schönlein, Martin, Méndez, Gustavo‐ Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciumè, Mariarita, Ammatuna, Emanuele, Cordoba, Raul, García‐Poutón, Nicole, Gräfe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, García‐Sanz, Ramón, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, De Kort, Elizabeth, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, Garcia‐Vidal, Carolina, Dargenio, Michelina, Danion, François, Machado, Marina, Bailén‐Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Chai, Louis Yi Ann, Kho, Chi Shan, Bonanni, Matteo, Liévin, Raphaël, Marchesi, Francesco, Cornely, Oliver A., and Pagano, Livio

Subjects
omicron SARS-CoV-2
Abstract

No abstract available

Published
2022

92. Análisis y propuestas para impulsar la descarbonización en la industria minera

Author

León Serrano, Laura Ly, Rodríguez Dono, Alfonso, Vargas Parra, María Violeta, and Universitat Politècnica de Catalunya. Departament d'Enginyeria Civil i Ambiental

Subjects
emisiones, impacto ambiental, Enginyeria civil::Enginyeria de mines [Àrees temàtiques de la UPC], Descarbonización, Mineral industries, Indústria minera, cambio climático, combustibles fósiles, energías renovables
Abstract

En el desarrollo de este trabajo se estudia la situación de la industria minera frente a la problemática medioambiental actual, por medio de una revisión extensa de la literatura de las que se incluyeron a lo largo del trabajo citas relevantes de informes, revistas y otros documentos de interés. Se identifican factores impulsores y alternativas que las empresas pueden implementar para la reducción de emisiones de CO2 y otras sustancias o para mitigar los daños producidos, tales como, mejoras en sus procesos, electrificación de vehículos y otras innovaciones de transporte, compensaciones y captura de carbono, o el uso de hidrógeno. También se identifican obstáculos técnicos, de experiencia y financiación que van a influir en la velocidad de la integración de tecnologías de descarbonización. Una vez hecho este trabajo de investigación, se seleccionan datos bibliográficos y analíticos de la producción de oro en la República Dominicana y por medio de la metodología de Análisis de Ciclo de Vida (ACV), utilizando el software SimaPro como herramienta, se evalúan las cargas del uso de combustibles fósiles en equipos móviles y electricidad en otros equipos de procesamiento de minerales. A partir del análisis realizado se plantean recomendaciones en forma de propuestas viables que ayuden la reducción del dióxido de carbono de las fuentes de energía, y, por tanto, a mitigar los impactos identificados. A su vez, se persigue que estas propuestas puedan servir de guía a otras empresas mineras, productores de energía independientes e instituciones de desarrollo sobre cómo acelerar la integración de las energías renovables en el sector minero. In the development of this work, the situation of the mining industry in the face of current environmental problems is studied by means of an extensive review of the literature, including relevant quotes from reports, journals and other documents of interest. Drivers and alternatives that companies can implement to reduce emissions of CO2 and other substances or to mitigate the damage produced are identified, such as improvements in their processes, electrification of vehicles and other transport innovations, carbon offsets and carbon capture, or the use of hydrogen. It also identifies technical, experience and funding barriers that will influence the speed of integration of decarbonization technologies. Once this research work is done, bibliographic and analytical data on gold production in the Dominican Republic is selected and by means of the Life Cycle Analysis (LCA) methodology, using SimaPro software as a tool, the burdens of the use of fossil fuels in mobile equipment and electricity in other mineral processing equipment are evaluated. Based on the analysis, recommendations are made in the form of viable proposals to help reduce carbon dioxide from energy sources and, therefore, mitigate the identified impacts. In turn, these proposals are intended to serve as a guide to other mining companies, independent power producers and development institutions on how to accelerate the integration of renewable energies in the mining sector.

Published
2022

93. Building Augmented and Virtual Reality Experiences for Children with Visual Diversity

Author

Navarro-Newball, Andres Adolfo, Sierra Galvis, Martín Vladimir Alonso, Martínez, Juan Carlos, Betancourt, Juan José, Ramirez, Katherine, Velasquez, Andrés, Quinto, Valeria, Restrepo, Gerardo, Castillo, Andrés Darío, Asprilla, Elizabeth, Portilla, Anita, Serrano, Laura Lucia, Rodríguez, Frank Alexander, and Peñaloza, Eliana

Subjects
Mixed / augmented reality, +Virtual+reality%22">CCS Concepts: Computing methodologies --> Virtual reality, Computing methodologies, Virtual reality
Abstract

Currently, a binational network of universities carries out a collaborative project which seeks to promote inclusion and education in environmental issues for children. The so-called ''Colombia-Québec collaborative project'' seeks to develop interactive narratives about four Colombian animals to help develop language, cognitive and motricity skills in children while they gain awareness of endangered animals. Chosen animals include the cotton top tamarin, the jaguar, the spectacled bear, and the condor. We are building several interactive systems which take advantage of augmented and virtual reality technologies to expand narratives developed by speech and language therapists. Our goal is to use these systems to study the effects of the virtuality continuum in visually diverse children's development. We present our advances towards achieving it., Visual Computing and Applications, Andres Adolfo Navarro-Newball, Martín Vladimir Alonso Sierra Galvis, Juan Carlos Martínez, Juan José Betancourt, Katherine Ramirez, Andrés Velasquez, Valeria Quinto, Gerardo Restrepo, Andrés Darío Castillo, Elizabeth Asprilla, Anita Portilla, Laura Lucia Serrano, Frank Alexander Rodríguez, and Eliana Peñaloza

Published
2022
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96. COVID-19 in vaccinated adult patients with hematological malignancies: preliminary results from EPICOVIDEHA

Author

Pagano, Livio, primary, Salmanton-García, Jon, additional, Marchesi, Francesco, additional, López-García, Alberto, additional, Lamure, Sylvain, additional, Itri, Federico, additional, Gomes-Silva, Maria, additional, Dragonetti, Giulia, additional, Falces-Romero, Iker, additional, van Doesum, Jaap, additional, Sili, Uluhan, additional, Labrador, Jorge, additional, Calbacho, Maria, additional, Bilgin, Yavuz M., additional, Weinbergerová, Barbora, additional, Serrano, Laura, additional, Ribera-Santa Susana, José-María, additional, Malak, Sandra, additional, Loureiro-Amigo, José, additional, Glenthøj, Andreas, additional, Córdoba-Mascuñano, Raúl, additional, Nunes-Rodrigues, Raquel, additional, González-López, Tomás-José, additional, Karlsson, Linda Katharina, additional, Jiménez-Lorenzo, María-Josefa, additional, Hernández-Rivas, José-Ángel, additional, Jaksic, Ozren, additional, Ráčil, Zdeněk, additional, Busca, Alessandro, additional, Corradini, Paolo, additional, Hoenigl, Martin, additional, Klimko, Nikolai, additional, Koehler, Philipp, additional, Pagliuca, Antonio, additional, Passamonti, Francesco, additional, and Cornely, Oliver A., additional

Published
2022
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97. Estudio y desarrollo de métodos de calibración para robots móviles

Author

Ortega Serrano, Laura

Subjects
Robot móvil. calibración, Mobile robot, Calibration, Máster Universitario en Ingeniería Mecatrónica-Màster Universitari en Enginyeria Mecatrònica, INGENIERIA DE SISTEMAS Y AUTOMATICA
Abstract

[ES] Este Trabajo Final de Máster procede de un proyecto entre la Universidad Politécnica de Valencia y la empresa "Robotnik" cuyo fin era el desarrollo de métodos para la autocalibración de parámetros cinemáticos de robots móviles. Estos son, básicamente, el radio y la disposición de las ruedas, necesarios para la estimación de posición por odometría. La odometría es el proceso de estimar la posición de un robot basándose en el camino recorrido por cada una de las ruedas. Se utiliza tanto para el control como para la estimación de la posición de los robots móviles. Para una buena estimación odométrica es importante el conocimiento exacto de algunos parámetros cinemáticos del vehículo como el radio de las ruedas, o la posición de estas. Estos parámetros, aunque normalmente conocidos, pueden cambiar con el paso del tiempo, debido, por ejemplo, al desgaste de las ruedas. Por ello puede ser necesario volver a calibrar el robot. La calibración se puede realizar por un operario o por el robot en solitario (autocalibración). En el primer caso, el robot ejecuta una serie de movimientos preprogramados. El usuario mide la desviación entre la trayectoria programada y la realizada, y a partir del error estima el error de los parámetros cinemáticos. Este método presenta la desventaja de que necesita la intervención de un operario. La alternativa es la autocalibración del robot, en cuyo caso se compara la trayectoria estimada por la odometría con la medida mediante un sistema de autolocalización (visión artificial, láser, u otro). Cabe resaltar que existen dos tipos de errores de odometría: los sistemáticos y los no sistemáticos. Los primeros son aquellos que vienen dados por la existencia de diferencias entre el robot teórico y el robot real. Estos son los que se deben deducir y corregir en este proyecto. Los errores no sistemáticos, por otro lado, son aquellos que no se pueden predecir y que se deben a irregularidades del terreno o fuerzas externas. Algunos errores no sistemáticos son derrapes (debidos a terreno arenoso o a una gran velocidad del robot) o los movimientos de subida y bajada del robot al moverse por un terreno que no es llano o donde hay objetos que suponen obstáculos. El objetivo de este proyecto es el estudio, desarrollo e implementación de técnicas de autocalibración de robots móviles de la compañía ¿Robotnik¿. Concretamente, se aplicará a robots con cinemática diferencial y robots omnidireccionales de cuatro ruedas mecanum. Se pretende así corregir los parámetros cinemáticos del robot (radio y disposición de las ruedas) comparando la posición del robot estimada por la odometría (recorrido de las ruedas) con otra fuente (sistema de visión, inercia, medidas manuales). Concretamente, para la toma de medidas se ha utilizado la cámara Intel T-265, que contiene un acelerómetro y un giróscopo además del sistema de visión artificial. También se han realizado medidas manuales para comparar los resultados. Para evitar los errores no-sistemáticos, se deben generar trayectorias suaves, además de asegurar un suelo llano y no resbaladizo. Mientras que para una buena identificación de parámetros es conveniente que la trayectoria sea lo más cambiante posible. En este proyecto se deberán buscar soluciones de compromiso entre los dos requerimientos contradictorios. Este proyecto incluye desde el estudio teórico de métodos de calibración y autocalibración, al desarrollo de nuevas propuestas de experimentos para la calibración de los dos tipos de robots mencionados., [EN] This Master’s Thesis comes from a project between the Universidad Politécnica de Valencia and the company “Robotnik” with the objective/intend of developing autocalibration methods for the kinematics parameters of mobile robots. These parameters are the wheels radii and their location on the robot, needed for the odometry implemented in the robot’s navigation. Odometry can be defined as a method that uses sensor measurements at the wheels to estimate the movement and position of the robot. It is used both for the control of the mobile robot as well as for its navigation. The initial parameters of any robot are known, but with time there may be variations due to wear or impacts, apart from the fact that there is a tolerance when manufacturing, which can result in an error in said parameters. It is here where the importance of being able to correctly estimate the kinematic parameters lays. The robots’ calibration can be carried out manually or automatically by the robot itself (autocalibration). For this the robot will perform a series of predefined movements and the error between the desired and the real trajectories will be measured either by a worker or by the robot through a series of sensors. Said error is then used to obtain the kinematics parameters of the robot. The manual calibration has the disadvantage of requiring someone else to take the measurements and perform the calculations. It is worth noting that there when studying the odometry of a mobile robot it is essential to consider the different types of errors that may cause an error in its movement. Systematic and non-systematic errors can be differentiated. Systematic errors are the ones caused by differences between the designed robot and the real one, this means lengths or radius that are not exactly what they should be. These are the errors that need to be gathered and reduced in this project. On the other hand, nonsystematic errors are caused by factors outside of the robot such as external forces or irregularities in the ground and cannot be predicted beforehand. The objective of this project is theoretical study and experimental endorsement of autocalibration methods in mobile robots from the company “Robotnik”. In particular, we will be working with the differential drive robot and the omnidirectional robot with four mecanum wheels. The aim is to correct the kinematic parameters of the robot (radius and wheel arrangement) by comparing the position of the robot estimated by odometry (wheel travel) with another source (vision system, inertia, manual measurements). Specifically, for taking measurements, the Intel T-265 camera has been used, which contains an accelerometer and a gyroscope in addition to the artificial vision system. Manual measurements have also been made to compare the results. To avoid non-systematic errors, smooth trajectories must be generated, in addition to ensuring a flat and non-slippery floor. But for a good identification of the required parameters, it is convenient that the trajectory be as exciting as possible. In this project, compromise solutions should be sought between the two contradictory requirements. This project covers from the theoretical study of calibration and self-calibration methods to the development of new experimental proposals for the calibration of the two types of robots mentioned.

Published
2021

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