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72 results on '"Selig, Sara"'

52. Biology of advanced uveal melanoma and next steps for clinical therapeutics

Author

Luke, Jason J., primary, Triozzi, Pierre L., additional, McKenna, Kyle C., additional, Van Meir, Erwin G., additional, Gershenwald, Jeffrey E., additional, Bastian, Boris C., additional, Gutkind, J. Silvio, additional, Bowcock, Anne M., additional, Streicher, Howard Z., additional, Patel, Poulam M., additional, Sato, Takami, additional, Sossman, Jeffery A., additional, Sznol, Mario, additional, Welch, Jack, additional, Thurin, Magdalena, additional, Selig, Sara, additional, Flaherty, Keith T., additional, and Carvajal, Richard D., additional

Published
2014
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55. Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress – Implications for tissue and organismal aging

Author

Shlush, Liran I., primary, Skorecki, Karl L., additional, Itzkovitz, Shalev, additional, Yehezkel, Shiran, additional, Segev, Yardena, additional, Shachar, Hofit, additional, Berkovitz, Ron, additional, Adir, Yochai, additional, Vulto, Irma, additional, Lansdorp, Peter M., additional, and Selig, Sara, additional

Published
2011
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57. Altered Chromosomal Positioning, Compaction, and Gene Expression with a Lamin A/C Gene Mutation

Author

Mewborn, Stephanie K., primary, Puckelwartz, Megan J., additional, Abuisneineh, Fida, additional, Fahrenbach, John P., additional, Zhang, Yuan, additional, MacLeod, Heather, additional, Dellefave, Lisa, additional, Pytel, Peter, additional, Selig, Sara, additional, Labno, Christine M., additional, Reddy, Karen, additional, Singh, Harinder, additional, and McNally, Elizabeth, additional

Published
2010
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61. Immune Responses to Measles and Tetanus Vaccines Among Kenyan Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Children Pre- and Post-Highly Active Antiretroviral Therapy and Revaccination

Author

Farquhar, Carey, primary, Wamalwa, Dalton, additional, Selig, Sara, additional, John-Stewart, Grace, additional, Mabuka, Jennifer, additional, Majiwa, Maxwel, additional, Sutton, William, additional, Haigwood, Nancy, additional, Wariua, Grace, additional, and Lohman-Payne, Barbara, additional

Published
2009
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63. Regulation of Murine Telomere Length by Rtel

Author

Ding, Hao, primary, Schertzer, Mike, additional, Wu, Xiaoli, additional, Gertsenstein, Marina, additional, Selig, Sara, additional, Kammori, Makoto, additional, Pourvali, Reza, additional, Poon, Steven, additional, Vulto, Irma, additional, Chavez, Elizabeth, additional, Tam, Patrick P.L, additional, Nagy, Andras, additional, and Lansdorp, Peter M, additional

Published
2004
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65. Biochemical and Biological Characterization of a Dodecameric CD4-Ig Fusion Protein

Author

Arthos, James, primary, Cicala, Claudia, additional, Steenbeke, Tavis D., additional, Chun, Tae-Wook, additional, Cruz, Charles Dela, additional, Hanback, Douglas B., additional, Khazanie, Prateeti, additional, Nam, Daniel, additional, Schuck, Peter, additional, Selig, Sara M., additional, Van Ryk, Donald, additional, Chaikin, Margery A., additional, and Fauci, Anthony S., additional

Published
2002
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70. Meeting Report From the 2023 Cure Ocular Melanoma (CURE OM) Global Science Meeting, Philadelphia, PA, November 2023.

Author

Seedor, Rino S., Aplin, Andrew E., Bertolotto, Corine, Carvajal, Richard D., Deacon, Nigel, Doble, Katie, Hamid, Omid, Haq, Rizwan, Kadosh, Miriam, Khan, Shaheer, Kraska, Jacqueline, Lutzky, Jose, McKean, Meredith, Montazeri, Kamaneh, Moser, Justin, Onken, Michael, Orloff, Marlana, Sacco, Joseph J., Smalley, Keiran, and Selig, Sara M.

Subjects
*PATIENT advocacy, *MELANOMA, *MEDICAL research, *FORUMS, *AWARENESS
Abstract

ABSTRACT The 2023 Cure Ocular Melanoma (CURE OM) Global Science Meeting was held in Philadelphia on November 6, 2023. There is increased awareness and dedicated research in uveal melanoma (UM), but unmet needs remain in the prevention, detection, and treatment of UM. The purpose of this meeting was to provide an international forum for the exchange of research ideas, to allow for discussion of basic science as well as clinical research on UM, and to gather input about advocacy and patient needs. [ABSTRACT FROM AUTHOR]

Published
2024
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71. Proceedings from the Melanoma Research Foundation Mucosal Melanoma Meeting (December 16, 2022, New York, USA).

Author

Wei AZ, Chen LN, Orloff M, Ariyan CE, Asgari M, Barker CA, Buchbinder E, Chandra S, Couts K, Frumovitz MM, Futreal A, Gershenwald JE, Hanna EY, Izar B, LeBlanc AK, Leitao MM Jr, Lipson EJ, Liu D, McCarter M, McQuade JL, Najjar Y, Rapisuwon S, Selig S, Shoushtari AN, Yeh I, Schwartz GK, Guo J, Patel SP, and Carvajal RD

Subjects
Humans, New York, Mucous Membrane pathology, Combined Modality Therapy, Neoplasm Staging, Melanoma therapy, Melanoma pathology
Abstract

Mucosal melanoma remains a rare cancer with high mortality and a paucity of therapeutic options. This is due in significant part to its low incidence leading to limited patient access to expert care and downstream clinical/basic science data for research interrogation. Clinical challenges such as delayed and at times inaccurate diagnoses, and lack of consensus tumor staging have added to the suboptimal outcomes for these patients. Clinical trials, while promising, have been difficult to activate and accrue. While individual institutions and investigators have attempted to seek solutions to such problems, international, national, and local partnership may provide the keys to more efficient and innovative paths forward. Furthermore, a mucosal melanoma coalition would provide a potential network for patients and caregivers to seek expert opinion and advice. The Melanoma Research Foundation Mucosal Melanoma Meeting (December 16, 2022, New York, USA) highlighted the current clinical challenges faced by patients, providers, and scientists, identified current and future clinical trial investigations in this rare disease space, and aimed to increase national and international collaboration among the mucosal melanoma community in an effort to improve patient outcomes. The included proceedings highlight the clinical challenges of mucosal melanoma, global clinical trial experience, basic science advances in mucosal melanoma, and future directions, including the creation of shared rare tumor registries and enhanced collaborations., (© 2023 The Authors. Pigment Cell & Melanoma Research published by John Wiley & Sons Ltd.)

Published
2023
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72. Digital image analysis of cells stained with the senescence-associated β-galactosidase assay.

Author

Shlush LI and Selig S

Subjects
Biomarkers metabolism, Cell Line, Cytoplasm metabolism, Humans, Staining and Labeling, beta-Galactosidase chemistry, Cellular Senescence physiology, Image Processing, Computer-Assisted methods
Abstract

Cellular senescence plays important roles in the aging process of complex organisms, in response to stress and in tumor suppression. Several markers can be used to identify senescent cells, of which the most widely used is the senescence-associated β-galactosidase (SABG) activity. Here we describe a procedure for digital image analysis of cells stained by the SABG staining technique at pH 6 or at pH 4. This analysis is highly reproducible and sensitive to subtle differences in staining intensities resulting from diverse cellular senescence pathways in culture.

Published
2013
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