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3,568 results on '"Schmitt D"'

51. Intraindividual Comparison of Physiologic [68Ga]Ga-PSMA-11 and [18F]PSMA-1007 Uptake in Ganglia in Patients with Prostate Cancer: a retrospective, monocentric analysis

Author

Novruzov, E., additional, Schmitt, D., additional, Mattes-György, K., additional, Beu, M., additional, Henke, J. M., additional, Antke, C., additional, Cardinale, J., additional, Niegisch, G., additional, Schimmöller, L., additional, Giesel, F. L., additional, and Mamlins, E., additional

Published
2023
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52. Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors.

Author

Dieu-Nosjean, MC, Massacrier, C, Homey, B, Vanbervliet, B, Pin, JJ, Vicari, A, Lebecque, S, Dezutter-Dambuyant, C, Schmitt, D, Zlotnik, A, and Caux, C

Subjects
Epithelium, Langerhans Cells, T-Lymphocytes, Cell Line, Stem Cells, Animals, Mice, Inbred BALB C, Humans, Mice, Psoriasis, Inflammation, Receptors, Chemokine, Chemokines, CC, Macrophage Inflammatory Proteins, Receptors, CCR6, Chemokine CCL20, dendritic cell, chemokine, migration, regulation, in vivo expression, Immunology, Medical and Health Sciences
Abstract

Dendritic cells (DCs) form a network comprising different populations that initiate and differentially regulate immune responses. Langerhans cells (LCs) represent a unique population of DCs colonizing epithelium, and we present here observations suggesting that macrophage inflammatory protein (MIP)-3alpha plays a central role in LC precursor recruitment into the epithelium during inflammation. (a) Among DC populations, MIP-3alpha was the most potent chemokine inducing the selective migration of in vitro-generated CD34(+) hematopoietic progenitor cell-derived LC precursors and skin LCs in accordance with the restricted MIP-3alpha receptor (CC chemokine receptor 6) expression to these cells. (b) MIP-3alpha was mainly produced by epithelial cells, and the migration of LC precursors induced by the supernatant of activated skin keratinocytes was completely blocked with an antibody against MIP-3alpha. (c) In vivo, MIP-3alpha was selectively produced at sites of inflammation as illustrated in tonsils and lesional psoriatic skin where MIP-3alpha upregulation appeared associated with an increase in LC turnover. (d) Finally, the secretion of MIP-3alpha was strongly upregulated by cells of epithelial origin after inflammatory stimuli (interleukin 1beta plus tumor necrosis factor alpha) or T cell signals. Results of this study suggest a major role of MIP-3alpha in epithelial colonization by LCs under inflammatory conditions and immune disorders, and might open new ways to control epithelial immunity.

Published
2000

56. Givinostat in DMD: Results of the EPIDYS Study with Particular Attention to MR Measures of Muscle Fat Fraction.

Author

Vandenborne, K., Wilcocks, R., Walter, G., Forbes, S., Kan, H. E., Cazzaniga, S., Bettica, P., Schmitt, D., Mercuri, E., and McDonald, C.

Subjects
NUCLEAR magnetic resonance spectroscopy, HISTONE deacetylase inhibitors, CLINICAL trials, DUCHENNE muscular dystrophy, FAT, MUSCLE strength
Abstract

The article discusses the results of a Phase 3 clinical trial (EPIDYS) that examined the safety and efficacy of Givinostat, a histone deacetylase inhibitor, in boys with Duchenne muscular dystrophy (DMD). The study found that Givinostat reduced muscle fat infiltration in DMD patients compared to a placebo, as measured by magnetic resonance spectroscopy (MRS). The treatment also showed positive effects on secondary endpoints, such as muscle strength and ambulation. The study concluded that Givinostat has the potential to ameliorate muscle deterioration in DMD patients and supports the use of quantitative MR biomarkers in clinical trials. [Extracted from the article]

Published
2023
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62. Probleme des Zielfindungsprozesses

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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63. Fazit

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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64. Strategien für eine kohärente Klimapolitik

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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65. Kriterien und Grundzüge einer rationalen Klimapolitik

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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66. Ziele und Grundsatze von Klimapolitik

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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67. Probleme der Bewertung von Klimaänderungen

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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68. Methodische Probleme transdisziplinärer Forschung zum Klimaproblem

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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69. Leistungsfähigkeit von Modellen

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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70. Belastbarkeit von Prognosen

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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71. Ökonomische Aspekte der Klimavorsorge

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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72. Klimaforschung

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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73. Ethische Aspekte des Klimawandels

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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74. Rechtlicher Rahmen

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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75. Das Vorhaben 'Klimavorhersage und Klimavorsorge'

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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76. Elemente einer rationalen Klimapolitik

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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77. Sachlage

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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78. Transdisziplinäre Beurteilung der Klimaproblematik

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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79. PSMA-1007 Uptake in Ganglia of the Sympathetic Trunk and Its Intra-individual Reproducibility

Author

Mamlins, E., primary, Schmitt, D., additional, Beu, M., additional, Mattes-György, K., additional, Henke, J. M., additional, Antke, C., additional, Novruzov, E., additional, Cardinale, J., additional, Kirchner, J., additional, Niegisch, G., additional, Radtke, J. P., additional, Schimmöller, L., additional, Albers, P., additional, Antoch, G., additional, and Giesel, F. L., additional

Published
2022
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80. Individualized Treatment Responsiveness as Quantified by Dynamic Changes in Cell Free HPV DNA in Patients Receiving Induction Chemotherapy and Definitive Chemoradiation for HPV-Related Head and Neck Cancer

Author

Cao, Y., primary, Kiess, A.P., additional, Hwang, M., additional, Boudadi, K., additional, Saloura, V., additional, Mattox, A.K., additional, Gramiccioni, E., additional, Schmitt, D., additional, Preston, J., additional, Starus, A., additional, Jones, F., additional, Seiwert, T.Y., additional, and Quon, H., additional

Published
2022
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84. Neurocognition and Quality of Life for Hypofractionated Stereotactic Radiotherapy (HFSRT) of the Resection Cavity vs. Whole-Brain Radiotherapy (WBRT) Following Brain Metastasis Resection – Results of the ESTRON Randomized Phase 2 Trial

Author

Shafie, R. El, Bernhardt, D., Welzel, T., Schiele, A., Schmitt, D., Thalmann, P., Erdem, S., Paul, A., Lang, K., Weykamp, F., Adeberg, S., Lentz-Hommertgen, A., Jaekel, C., Bozorgmehr, F., Thomas, M., Kieser, M., Debus, J., and Rieken, S.

Published
2024
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87. Stand Structure, Transpiration Responses in Trees and Vines and Stand Transpiration of Different Forest Types Within the Mountain Rainforest

Author

Küppers, M., Motzer, T., Schmitt, D., Ohlemacher, C., Zimmermann, R., Horna, V., Küppers, B. I. L., Mette, T., Caldwell, M. M., editor, Heldmaier, G., editor, Jackson, R. B., editor, Lange, O. L., editor, Mooney, H. A., editor, Schulze, E. -D., editor, Sommer, U., editor, Beck, Erwin, editor, Bendix, Jörg, editor, Kottke, Ingrid, editor, Makeschin, Franz, editor, and Mosandl, Reinhard, editor

Published
2008
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91. Ziele und Stellenwert

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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92. Wissenschaftlich-deskriptive Problemskizze

Author

Schröder, Meinhard, Wütscher, Friederike, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., Gethmann, Carl Friedrich, editor, Schröder, Meinhard, Claussen, M., Grunwald, A., Hense, A., Klepper, G., Lingner, S., Ott, K., Schmitt, D., Sprinz, D., and Wütscher, Friederike, editor

Published
2002
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97. Coping with global uncertainty: Perceptions of COVID-19 psychological distress, relationship quality, and dyadic coping for romantic partners across 27 countries

Author

Randall, A. K., Leon, G., Basili, E., Martos, T., Boiger, M., Baldi, M., Hocker, L., Kline, K., Masturzi, A., Aryeetey, R., Bar-Kalifa, E., Boon, S. D., Botella, L., Burke, T., Carnelley, K., Carr, A., Dash, A., Fitriana, M., Gaines, S. O., Galdiolo, S., Claire M, H., Joo, S., Kanth, B., Karademas, E., Karantzas, G., Landolt, S. A., Mchugh, L., Milek, A., Murphy, E., Natividade, J. C., Portugal, A., Quinones, A., Relvas, A. P., Rumondor, P. C. B., Rusu, P., Sallay, V., Saul, L. A., Schmitt, D. P., Sels, L., Shujja, S., Taylor, L. K., Ozguluk, S. B., Verhofstadt, L., Yoo, G., Zemp, M., Donato, Silvia, Totenhagen, C. J., van Eickels, R. L., Anaba, E. A., Beauchemin-Roy, S., Berry, A., Brassard, A., Chesterman, S., Ferguson, L., Fonseca, G., Gaugue, J., Geonet, M., Hermesch, N., Knox, L., Lafontaine, M. -F., Lawless, N., Londero-Santos, A., Major, S., Marot, T. A., Mullins, E., Otermans, P. C. J., Ariela F, P., Parise, Miriam, Parvin, R., De, M., Peloquin, K., Rebelo, B., Righetti, F., Romano, D., Salavati, S., Samrock, S., Serea, M., Seok, C. B., Sotero, L., Stafford, O., Thomadakis, C., Topcu-Uzer, C., Ugarte, C., Yun, L. W., Simon-Zambori, P., Siau, C. S., Duca, D. -S., Filip, C., Park, H., Wearen, S., Bodenmann, G., Chiarolanza, C., Donato S. (ORCID:0000-0002-8406-4604), Parise M. (ORCID:0000-0003-2150-6636), Randall, A. K., Leon, G., Basili, E., Martos, T., Boiger, M., Baldi, M., Hocker, L., Kline, K., Masturzi, A., Aryeetey, R., Bar-Kalifa, E., Boon, S. D., Botella, L., Burke, T., Carnelley, K., Carr, A., Dash, A., Fitriana, M., Gaines, S. O., Galdiolo, S., Claire M, H., Joo, S., Kanth, B., Karademas, E., Karantzas, G., Landolt, S. A., Mchugh, L., Milek, A., Murphy, E., Natividade, J. C., Portugal, A., Quinones, A., Relvas, A. P., Rumondor, P. C. B., Rusu, P., Sallay, V., Saul, L. A., Schmitt, D. P., Sels, L., Shujja, S., Taylor, L. K., Ozguluk, S. B., Verhofstadt, L., Yoo, G., Zemp, M., Donato, Silvia, Totenhagen, C. J., van Eickels, R. L., Anaba, E. A., Beauchemin-Roy, S., Berry, A., Brassard, A., Chesterman, S., Ferguson, L., Fonseca, G., Gaugue, J., Geonet, M., Hermesch, N., Knox, L., Lafontaine, M. -F., Lawless, N., Londero-Santos, A., Major, S., Marot, T. A., Mullins, E., Otermans, P. C. J., Ariela F, P., Parise, Miriam, Parvin, R., De, M., Peloquin, K., Rebelo, B., Righetti, F., Romano, D., Salavati, S., Samrock, S., Serea, M., Seok, C. B., Sotero, L., Stafford, O., Thomadakis, C., Topcu-Uzer, C., Ugarte, C., Yun, L. W., Simon-Zambori, P., Siau, C. S., Duca, D. -S., Filip, C., Park, H., Wearen, S., Bodenmann, G., Chiarolanza, C., Donato S. (ORCID:0000-0002-8406-4604), and Parise M. (ORCID:0000-0003-2150-6636)

Abstract

Following the global outbreak of COVID-19 in March 2020, individuals report psychological distress associated with the “new normal”—social distancing, financial hardships, and increased responsibilities while working from home. Given the interpersonal nature of stress and coping responses between romantic partners, based on the systemic transactional model this study posits that perceived partner dyadic coping may be an important moderator between experiences of COVID-19 psychological distress and relationship quality. To examine these associations, self-report data from 14,020 people across 27 countries were collected during the early phases of the COVID-19 pandemic (March–July, 2020). It was hypothesized that higher symptoms of psychological distress would be reported post-COVID-19 compared to pre-COVID-19 restrictions (Hypothesis 1), reports of post-COVID-19 psychological distress would be negatively associated with relationship quality (Hypothesis 2), and perceived partner DC would moderate these associations (Hypothesis 3). While hypotheses were generally supported, results also showed interesting between-country variability. Limitations and future directions are presented.

Published
2022

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