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57. 21. Mainzer Allergie-Workshop

Author

Rennert, S., primary, Krause, S., additional, Becker, W., additional, Petersen, A., additional, Schocker, F., additional, Papenfuß, K., additional, Jappe, U., additional, Brehler, R., additional, Lange, L., additional, Riffelmann, F., additional, Nemat, K., additional, Hompes, S., additional, Holzhauser, T., additional, Lidholm, J., additional, Reese, G., additional, Vieths, S., additional, Seismann, H., additional, Blank, S., additional, Braren, I., additional, Greunke, K., additional, Cifuentes, L., additional, Grunwald, T., additional, Bredehorst, R., additional, Ollert, M., additional, Spillner, E., additional, von der Gathen, Y., additional, Sander, I., additional, Flagge, A., additional, Brüning, T., additional, Raulf-Heimsoth, M., additional, Zahradnik, E., additional, Fleischer, C., additional, Schierl, R., additional, Sültz, J., additional, Nowak, D., additional, Buters, J., additional, Weichenmeier, I., additional, Ochs, S., additional, Kreyling, W., additional, Boere, A., additional, Schober, W., additional, Behrendt, H., additional, Jaeger, T., additional, Kerzl, R., additional, Huss-Marp, J., additional, Ring, J., additional, Darsow, U., additional, Roeschmann, K., additional, Vroling, A., additional, van Drunen, C., additional, Ulmer, A., additional, Gilles, S., additional, Mariani, V., additional, Zhang, X., additional, Jakob, T., additional, Müller, M., additional, Pastore, S., additional, Traidl-Hoffmann, C., additional, Oeder, S., additional, Dietrich, S., additional, Fromme, H., additional, Schäfer, V., additional, Renne, J., additional, Werfel, T., additional, Wittmann, M., additional, Grusser, M., additional, Maurer, M., additional, Dudeck, A., additional, Suender, C., additional, Heydrich, S., additional, Bros, M., additional, Wiechmann, N., additional, Besche, V., additional, Hövelmeyer, N., additional, Reissig, S., additional, Massoumi, R., additional, Grabbe, S., additional, Waisman, A., additional, Reske-Kunz, A., additional, Gschwandtner, M., additional, Roßbach, K., additional, Bäumer, W., additional, Kietzmann, M., additional, Dijkstra, D., additional, Stark, H., additional, Gutzmer, R., additional, Höhn, Y., additional, Thamsen, M., additional, Trojandt, S., additional, Bovensiepen, C., additional, Bellinghausen, I., additional, Hilmenyuk, T., additional, Saloga, J., additional, Luxemburger, U., additional, Türeci, Ö., additional, Wiesner, H., additional, Kohlrautz, V., additional, Wahn, U., additional, Stock, P., additional, Mommert, S., additional, Köther, G., additional, Sudowe, S., additional, Barwig, C., additional, Montermann, E., additional, Milovanovic, M., additional, Koch, C., additional, Hilt, K., additional, Hartmann, B., additional, Heine, G., additional, Worm, M., additional, Ambach, A., additional, Hoefeld-Fegeler, M., additional, Besser, C., additional, Weren, A., additional, Schraven, B., additional, Bonekoh, B., additional, Gollnick, H., additional, Raap, M., additional, Bruder, M., additional, Kapp, A., additional, Raap, U., additional, Grosber, M., additional, Hausteiner, C., additional, Bubel, E., additional, Groben, S., additional, Bornschein, S., additional, Lahmann, C., additional, Zilker, T., additional, Eberlein, B., additional, Henningsen, P., additional, Huber, D., additional, Biedermann, T., additional, Kunz, J., additional, Fischer, J., additional, Kempf, W., additional, Wölbing, F., additional, Alexopoulou, A., additional, Albert, A., additional, Pfaar, O., additional, Distler, A., additional, Hörmann, K., additional, Klimek, L., additional, Wieczorek, D., additional, Büsing, M., additional, Wedi, B., additional, Rerinck, H.-C., additional, Przybilla, B., additional, Ruëff, F., additional, Weigert, C., additional, Ghoreschi, K., additional, Röcken, M., additional, Muhr, P., additional, Zeitvogel, J., additional, Ott, H., additional, Wiederholt, T., additional, Andresen-Bergström, M., additional, Skazik, C., additional, Merk, H., additional, Karlberg, A., additional, Zwadlo-Klarwasser, G., additional, Baron, J., additional, Frankenberg, U., additional, Lorenz, N., additional, Steinbrink, K., additional, Pföhler, C., additional, Dietrich, K.-A., additional, Thomas, P., additional, Baran, W., additional, Hänsel, A., additional, Meurer, M., additional, Schäkel, K., additional, Mamerow, D., additional, Niebuhr, M., additional, Bonnekoh, B., additional, Bunselmeyer, B., additional, Laubach, H., additional, Schiller, M., additional, Stanke, M., additional, Luger, T., additional, Böcking, C., additional, Köllisch, G., additional, Pfefferle, P., additional, Renz, H., additional, Conrad, M., additional, Teich, R., additional, Ferstl, R., additional, Brand, S., additional, Yildirim, A., additional, Kirschning, C., additional, Garn, H., additional, Eilbacher, I., additional, Stein, K., additional, Hanuszkiewicz, A., additional, Holst, O., additional, Heine, H., additional, Guenova, E., additional, Hoetzenecker, W., additional, Mailhammer, R., additional, Weindl, G., additional, Sauer, K., additional, Schaller, M., additional, Hiller, J., additional, Förster, S., additional, Eyerich, K., additional, Hofmann, H., additional, Ilchmann, A., additional, Burgdorf, S., additional, Waibler, Z., additional, Kurts, C., additional, Scheurer, S., additional, Kalinke, U., additional, Toda, M., additional, Adler, H. S., additional, Hofmann, C., additional, Becker, C., additional, Hemmer, W., additional, Focke, M., additional, Marzban, G., additional, Mayer, D., additional, Laimer, M., additional, Jarisch, R., additional, McIntyre, M., additional, Thiebes, V., additional, Mempel, M., additional, Jeßberger, B., additional, Vrtala, S., additional, Mauss, V., additional, Eben, R., additional, Walker, A. I., additional, Herzinger, T., additional, Berking, C., additional, Reese, I., additional, Sonar, S., additional, Ehmke, M., additional, Dietze, J., additional, Nockher, W., additional, Reuter, S., additional, Dehzad, N., additional, Martin, H., additional, Jung, M., additional, Heinz, A., additional, Stassen, M., additional, Buhl, R., additional, Taube, C., additional, Lingner, S., additional, Hennig, C., additional, Remke, J., additional, Hansen, G., additional, Dittrich, A., additional, Peters, M., additional, Bufe, A., additional, Polte, T., additional, Schütze, N., additional, Simon, J., additional, Lehmann, I., additional, Albrecht, M., additional, Preston-Hurlburt, P., additional, Bottomoly, H., additional, Pilzner, C., additional, Bühling, F., additional, Reinheckel, T., additional, Lauenstein, H., additional, Braun, A., additional, Welte, T., additional, Groneberg, D., additional, Greiner, T., additional, Zimmer, A., additional, Abram, M., additional, Fokuhl, V., additional, Luger, E., additional, Radbruch, A., additional, Zemlin, M., additional, Kilic, A., additional, Yildirim, A. Ö., additional, Alrifai, M., additional, Hagner, S., additional, Renzing, A., additional, Closs, E., additional, Bopp, T., additional, Schmitt, E., additional, Dicke, T., additional, Seyfarth, F., additional, Hipler, U., additional, Elsner, P., additional, Schliemann, S., additional, Konakovsky, V., additional, Moser, P., additional, Wantke, F., additional, Sesztak-Greinecker, G., additional, Götz, M., additional, Schmid, R., additional, and Hoffmann-Sommergruber, K., additional

Published
2009
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74. Zytotoxizitätsuntersuchung von hochgoldhaltigen Degutan-Oberflächen unterschiedlicher Rauhigkeit mit Fibroblasten (BALB 3T3) und Osteoblasten (hFOB 1.19) - Cytotoxicity of Degutan Surfaces of Different Roughness Using Fibroblast (BALB 3T3) and Osteoblast (hFOB 1.19) Cell Cultures

Author

Altvater, T, primary, Hendrich, C., additional, Noth, U., additional, Rader, C. P., additional, Stach, R., additional, Schütze, N., additional, Eulert, J., additional, and Thull, R., additional

Published
2000
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75. Standardisierte Testung von Skelett-Implantatoberflächen mit einem Osteoblasten-Zellkultursystem. III. PVD-Hartstoffbeschichtungen und Ti6AI4V - Standardised Testing of Bone/Implant Interfaces using an Osteoblast Cell Culture System. III. PVD Hard Coatings and Ti6AI4V

Author

Steinert, A., primary, Hendrich, C., additional, Merklein, F., additional, Rader, C. P., additional, Schütze, N., additional, Thull, R., additional, and Eulert, J., additional

Published
2000
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77. Standardisiertes Testen von Skelett-Implantatoberflächen mit einem Osteoblasten-Zellkultursystem. II. Titanoberflächen unterschiedlicher Rauhigkeit - Standardised Testing of Bone-implant Surfaces using an Osteoblast Gell Culture System. II. Titanium Surfaces of varying Degrees of Roughness

Author

Nöth, U., primary, Hendrich, C., additional, Merklein, F., additional, Altvater, T., additional, Rader, C.P., additional, Schütze, N., additional, Eulert, J., additional, and Thull, R., additional

Published
1999
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80. Standardisiertes Testen von Skelett-lmplantatoberflächen mit einem Osteoblasten-Zellkultursystem. I. Orthopädische Standardmaterialien. Standardised Testing of Bone-implant Surfaces Using an Osteoblast Cell Culture System. Part I: Standard Materials in Orthopaedic Surgery

Author

Merklein, F., primary, Hendrich, C, additional, Nöth, U., additional, Kochinki, G., additional, Rader, C. P., additional, Schütze, N., additional, Thull, R., additional, and Eulert, J., additional

Published
1998
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84. Polycentric Water Governance in Spain

Author

Schütze, Nora

Subjects
Water Governance, Irrigation, Agriculture, Environment, Polycentric Governance, Spain, Politics, Europe, European Politics, Environmental Policy, Administration, Human Ecology, Political Science, thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSN International institutions, thema EDItEUR::1 Place qualifiers::1Q Other geographical groupings: Oceans and seas, historical, political etc::1QF Political, socio-economic, cultural and strategic groupings::1QFE EU (European Union), thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPQ Central / national / federal government::JPQB Central / national / federal government policies, thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPP Public administration
Abstract

Increasing irrigation efficiency has been high on the political agenda in Spain for many years. However, the overarching aim to reduce agricultural water consumption has not been met so far. To explore this phenomenon, Nora Schütze investigates processes of coordination between the water and agricultural sector in three Spanish river basins in the context of the EU Water Framework Directive implementation. From the perspective of polycentric governance, she identifies multiple mechanisms which illustrate how and why actors interact in certain ways, and thus shows why environmental aims of the Water Framework Directive remain unachieved.

Published
2023
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85. Exposure to mycotoxins increases the allergic immune response in a murine asthma model.

Author

Schütze N, Lehmann I, Bönisch U, Simon JC, Polte T, Schütze, Nicole, Lehmann, Irina, Bönisch, Ulrike, Simon, Jan C, and Polte, Tobias

Abstract

Rationale: Epidemiological studies have shown that indoor molds are associated with increased prevalence and exacerbation of respiratory symptoms and asthma. Mycotoxins, secondary metabolites of molds, may contribute to these effects.Objectives: To investigate the adjuvant activity of mycotoxins on allergic airway inflammation.Methods: Balb/c mice were exposed via the airways to gliotoxin and via the intestine to patulin, sensitized with ovalbumin (OVA), and then analyzed in acute and chronic murine asthma models. In addition, the effect of mycotoxin exposure on dendritic cell (DC) function was investigated using murine bone marrow-derived DCs.Measurements and Main Results: Exposure of mice to both mycotoxins enhanced dose-dependently airway hyperreactivity, eosinophilic lung inflammation, and OVA-specific IgE serum levels compared with mice that received only the antigen. These findings correlated with increased Th2 cytokine levels and decreased IFN-gamma production. Long-term mycotoxin exposure exacerbated chronic airway inflammation and airway remodeling. In vitro or in vivo mycotoxin exposure inhibited IL-12 production in maturing DCs and enhanced airway inflammation after adoptive DC transfer into Balb/c mice. Mycotoxin exposure enhanced OVA-induced lung lipid peroxidation and moderately increased isoprostane levels in naive mice. Treatment of mycotoxin-exposed DCs with the antioxidants N-acetylcysteine or glutathione ethyl ester restored IL-12 secretion and pretreatment of exposed mice with N-acetylcysteine prevented the mycotoxin-induced increase of airway inflammation and AHR.Conclusions: Our results demonstrate that gliotoxin and patulin increase the allergic immune response in mice by modulating the Th1/Th2 balance via direct effects on IL-12 secretion in DCs and by inducing oxidative stress. [ABSTRACT FROM AUTHOR]

Published
2010
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91. Novel simulation-based algorithms for optimal open-loop and closed-loop scheduling of deficit irrigation systems.

Author

Schütze, N., de Paly, M., and Shamir, U.

Subjects
*DEFICIT irrigation, *ALGORITHMS, *FLUID dynamics, *IRRIGATION scheduling, *SCARCITY, *AGRICULTURAL productivity, *WATER supply
Abstract

The scarcity of water compared with the abundance of land constitutes the main drawback within agricultural production. Besides the improvement of irrigation techniques a task of primary importance is solving the problem of intra-seasonal irrigation scheduling under limited seasonal water supply. An efficient scheduling algorithm has to take into account the crops' response to water stress at different stages throughout the growing season. Furthermore, for large-scale planning tools compact presentations of the relationship between irrigation practices and grain yield, such as crop water production functions, are often used which also rely on an optimal scheduling of the considered irrigation systems. In this study, two new optimization algorithms for single-crop intraseasonal scheduling of deficit irrigation systems are introduced which are able to operate with general crop growth simulation models. First, a tailored evolutionary optimization technique (EA) searches for optimal schedules over a whole growing season within an open-loop optimization framework. Second, a neuro-dynamic programming technique (NDP) is used for determining optimal irrigation policy. In this paper, different management schemes are considered and crop-yield functions generated with both the EA and the NDP optimization algorithms compared. [ABSTRACT FROM AUTHOR]

Published
2012
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97. Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is associated with IL-23-dependent IL-22, but not IL-17

Author

Schulz, S. M., Köhler, G., Schütze, N., Knauer, J., Reinhard Straubinger, Chackerian, A. A., Witte, E., Wolk, K., Sabat, R., Iwakura, Y., Holscher, C., Müller, U., Kastelein, R. A., Alber, G., and Publica

Subjects
Salmonella enterica
Abstract

IL-12 is essential for protective T cell-mediated immunity against Salmonella infection. To characterize the role of the related cytokine IL-23, wild-type (WT) C57BL/6 and p19 -/-mice were infected systemically with an attenuated strain of Salmonella enterica serovar Enteritidis (S. Enteritidis). IL-23-deficient mice controlled infection with S. Enteritidis similarly as WT mice. Similar IFN-{gamma} production as compared with WT mice, but defective IL-17A and IL-22 production was found in the absence of IL-23. Nevertheless, although IL-23 is required for T cell-dependent cytokine responses, IL-23 is dispensable for protection against S. Enteritidis when IL-12 is present. To analyze the role of IL-23 in the absence of IL-12, low doses of S. Enteritidis were administered to p35 -/- mice (lacking IL-12), p35/19 -/- mice (lacking IL-12 and IL-23), p35/40 -/- mice (lacking IL-12, IL-23, and homodimeric IL-12p40), or p35/IL-17A -/- mice (lacking IL-12 and IL-17A). We found survival of p35 -/-and p35/IL-17A -/- mice, whereas p35/19 -/- and p35/40 -/-mice died within 3-6 wk and developed liver necrosis. This indicates that IL-23, but not homodimeric IL-12p40, is required for protection, which, surprisingly, is independent of IL-17A. Moreover, protection was associated with IL-22, but not IL-17F or IL-21 expression or with neutrophil recruitment. Finally, anti-IL-22 treatment of S. Enteritidis-infected p35 -/- mice resulted in liver necrosis, indicating a central role of IL-22 in hepatocyte protection during salmonellosis. In conclusion, IL-23-dependent IL-22, but not IL-17 production is associated with protection against systemic infection with S. Enteritidis in the absence of IL-12.

98. Latest news,Aktuelles

Author

Jochen Hack, Siegel, K., Disse, M., Evers, M., Taft, L., Heinz, I., Schulte, A., Reinhardt-Imjela, C., Krois, J., Breuer, L., Multsch, S., and Schütze, N.

99. Monumenta Landgraviorum Thuringiae et Marchionum Misniae, quae adhuc in Thuringia Misnia Saxonia Superiore Franconia Et Hassia extant : Historico-Genealogica descriptione illustrata

Author

Göbel, J. G., Schütze, N., Kilian, Lucas, Reyher, Samuel, Göbel, J. G., Schütze, N., Kilian, Lucas, and Reyher, Samuel

Abstract

a Samuele Reyhero ..., Nicht identisch mit VD17 14:051705D (z.B. anderer Druck auf Bl. [2] und deshalb abweichender Fingerpr.) und VD17 7:696340T (Widmung abweichend gesetzt, aber kein anderer Fingerprint), Schlüsselseiten aus dem Exemplar der SLUB Dresden: Hist.Sax.E.9, Signaturformel (ohne Ill.): [1], A - Z2, Aa - Mm2, Vorlageform des Erscheinungsvermerks: In aes incisa et typis exscripta Gothae M.DC.XCII.

100. Monumenta Landgraviorum Thuringiae et Marchionum Misniae, quae adhuc in Thuringia Misnia Saxonia Superiore Franconia Et Hassia extant : Historico-Genealogica descriptione illustrata

Author

Göbel, J. G., Schütze, N., Kilian, Lucas, Reyher, Samuel, Göbel, J. G., Schütze, N., Kilian, Lucas, and Reyher, Samuel

Abstract

a Samuele Reyhero ..., Nicht identisch mit VD17 14:051705D (z.B. anderer Druck auf Bl. [2] und deshalb abweichender Fingerpr.) und VD17 7:696340T (Widmung abweichend gesetzt, aber kein anderer Fingerprint), Schlüsselseiten aus dem Exemplar der SLUB Dresden: Hist.Sax.E.9, Signaturformel (ohne Ill.): [1], A - Z2, Aa - Mm2, Vorlageform des Erscheinungsvermerks: In aes incisa et typis exscripta Gothae M.DC.XCII.

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