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16,744 results on '"Sapienza, A."'

52. Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome

Author

Klee, Matthias, Aho, V. T. E., May, P., Heintz-Buschart, A., Landoulsi, Z., Jónsdóttir, S. R., Pauly, C., Pavelka, L., Delacour, L., Kaysen, A., Krüger, R., Wilmes, P., Leist, A. K., Acharya, Geeta, Aguayo, Gloria, Alexandre, Myriam, Ali, Muhammad, Ammerlann, Wim, Arena, Giuseppe, Bassis, Michele, Batutu, Roxane, Beaumont, Katy, Béchet, Sibylle, Berchem, Guy, Bisdorff, Alexandre, Boussaad, Ibrahim, Bouvier, David, Castillo, Lorieza, Contesotto, Gessica, De Bremaeker, Nancy, Dewitt, Brian, Diederich, Nico, Dondelinger, Rene, Ramia, Nancy E, Ferrari, Angelo, Frauenknecht, Katrin, Fritz, Joëlle, Gamio, Carlos, Gantenbein, Manon, Gawron, Piotr, Georges, Laura, Ghosh, Soumyabrata, Giraitis, Marijus, Glaab, Enrico, Goergen, Martine, Gómez De Lope, Elisa, Graas, Jérôme, Graziano, Mariella, Groues, Valentin, Grünewald, Anne, Hammot, Gaël, Hanff, Anne-Marie, Hansen, Linda, Heneka, Michael, Henry, Estelle, Henry, Margaux, Herbrink, Sylvia, Herzinger, Sascha, Hundt, Alexander, Jacoby, Nadine, Jónsdóttir, Sonja, Klucken, Jochen, Kofanova, Olga, Krüger, Rejko, Lambert, Pauline, Landoulsi, Zied, Lentz, Roseline, Longhino, Laura, Lopes, Ana Festas, Lorentz, Victoria, Marques, Tainá M., Marques, Guilherme, Martins Conde, Patricia, May, Patrick, Mcintyre, Deborah, Mediouni, Chouaib, Meisch, Francoise, Mendibide, Alexia, Menster, Myriam, Minelli, Maura, Mittelbronn, Michel, Mtimet, Saïda, Munsch, Maeva, Nati, Romain, Nehrbass, Ulf, Nickels, Sarah, Nicolai, Beatrice, Nicolay, Jean-Paul, Noor, Fozia, Gomes, Clarissa P. C., Pachchek, Sinthuja, Pauly, Claire, Pauly, Laure, Pavelka, Lukas, Perquin, Magali, Pexaras, Achilleas, Rauschenberger, Armin, Rawal, Rajesh, Reddy Bobbili, Dheeraj, Remark, Lucie, Richard, Ilsé, Roland, Olivia, Roomp, Kirsten, Rosales, Eduardo, Sapienza, Stefano, Satagopam, Venkata, Schmitz, Sabine, Schneider, Reinhard, Schwamborn, Jens, Severino, Raquel, Sharify, Amir, Soare, Ruxandra, Soboleva, Ekaterina, Sokolowska, Kate, Theresine, Maud, Thien, Hermann, Thiry, Elodie, Ting Jiin Loo, Rebecca, Trouet, Johanna, Tsurkalenko, Olena, Vaillant, Michel, Vega, Carlos, Vilas Boas, Liliana, Wilmes, Paul, Wollscheid-Lengeling, Evi, and Zelimkhanov, Gelani

Published
2024
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53. Acute cholecystitis management in high-risk, critically ill, and unfit-for-surgery patients: the Italian Society of Emergency Surgery and Trauma (SICUT) guidelines

Author

Coccolini, Federico, Cucinotta, Eugenio, Mingoli, Andrea, Zago, Mauro, Altieri, Gaia, Biloslavo, Alan, Caronna, Roberto, Cengeli, Ismail, Cicuttin, Enrico, Cirocchi, Roberto, Cobuccio, Luigi, Costa, Gianluca, Cozza, Valerio, Cremonini, Camilla, Del Vecchio, Giovanni, Dinatale, Giuseppe, Fico, Valeria, Galatioto, Christian, Kuriara, Hayato, Lacavalla, Domenico, La Greca, Antonio, Larghi, Alberto, Mariani, Diego, Mirco, Paolo, Occhionorelli, Savino, Parini, Dario, Polistina, Francesco, Rimbas, Mihai, Sapienza, Paolo, Tartaglia, Dario, Tropeano, Giuseppe, Venezia, Piero, Venezia, Dario Francesco, Zaghi, Claudia, and Chiarugi, Massimo

Published
2024
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54. Searches for neutrinos in the direction of radio-bright blazars with the ANTARES telescope

Author

ANTARES Collaboration, Albert, A., Alves, S., André, M., Ardid, M., Ardid, S., Aubert, J. J., Aublin, J, Baret, B., Basa, S., Becherini, Y., Belhorma, B., Bendahman, M., Benfenati, F., Bertin, V., Biagi, S., Bissinger, M., Boumaaza, J., Bouta, M., Bouwhuis, M. C., Brânzaş, H., Bruijn, R., Brunner, J., Busto, J., Caiffi, B., Calvo, D., Campion, S., Capone, A., Caramete, L., Carenini, F., Carr, J., Carretero, V., Celli, S., Cerisy, L., Chabab, M., Moursli, R. Cherkaoui El, Chiarusi, T., Circella, M., Coelho, J. A. B., Coleiro, A., Coniglione, R., Coyle, P., Creusot, A., Cruz, A. S. M., Díaz, A. F., De Martino, B., Distefano, C., Di Palma, I., Domi, A., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., van Eeden, T., van Eijk, D., Hedri, S. El, Khayati, N. El, Enzenhöfer, A., Fermani, P., Ferrara, G., Filippini, F., Fusco, L., Gagliardini, S., García, J., Oliver, C. Gatius, Gay, P., Geißelbrecht, N., Glotin, H., Gozzini, R., Ruiz, R. Gracia, Graf, K., Guidi, C., Haegel, L., Hallmann, S., van Haren, H., Heijboer, A. J., Hello, Y., Hernández-Rey, J. J., Hößl, J., Hofestädt, J., Huang, F., Illuminati, G., James, C. W., Jisse-Jung, B., de Jong, M., de Jong, P., Kadler, M., Kalekin, O., Katz, U., Kouchner, A., Kovalev, Y. A, Kovalev, Y. Y, Kreykenbohm, I., Kulikovskiy, V., Lahmann, R., Lamoureux, M., Lazo, A., Lefèvre, D., Leonora, E., Levi, G., Stum, S. Le, Lopez-Coto, D., Loucatos, S., Maderer, L., Manczak, J., Marcelin, M., Margiotta, A., Marinelli, A., Martínez-Mora, J. A., Migliozzi, P., Moussa, A., Muller, R., Navas, S., Nezri, E., Fearraigh, B. Ó, Oukacha, E., Păun, A., Păvălaş, G. E., Peña-Martínez, S., Perrin-Terrin, M., Pestel, V., Piattelli, P., Plavin, A., Poirè, C., Popa, V., Pradier, T., Pushkarev, A., Randazzo, N., Real, D., Reck, S., Riccobene, G., Romanov, A., Sánchez-Losa, A., Saina, A., Greus, F. Salesa, Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schnabel, J., Schumann, J., Schüssler, F., Seneca, J., Spurio, M., Stolarczyk, Th., Taiuti, M., Tayalati, Y., Tingay, S. J., Troitsky, S., Vallage, B., Vannoye, G., Van Elewyck, V., Viola, S., Vivolo, D., Wilms, J., Zavatarelli, S., Zegarelli, A., Zornoza, J. D., Zúñiga, J., Collaboration, OVRO, Hovatta, T., Kiehlmann, S., Liodakis, I., Pavlidou, V., and Readhead, A. C. S

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Active galaxies, especially blazars, are among the most promising neutrino source candidates. To date, ANTARES searches for these objects considered GeV-TeV $\gamma$-ray bright blazars. Here, a statistically complete radio-bright blazar sample is used as the target for searches of origins of neutrinos collected by the ANTARES neutrino telescope over 13 years of operation. The hypothesis of a neutrino-blazar directional correlation is tested by pair counting and by a complementary likelihood-based approach. The resulting post-trial $p$-value is $3.0\%$ ($2.2\sigma$ in the two-sided convention), possibly indicating a correlation. Additionally, a time-dependent analysis is performed to search for temporal clustering of neutrino candidates as a mean of detecting neutrino flares in blazars. None of the investigated sources alone reaches a significant flare detection level. However, the presence of 18 sources with a pre-trial significance above $3\sigma$ indicates a $p=1.4\%$ ($2.5\sigma$ in the two-sided convention) detection of a time-variable neutrino flux. An \textit{a posteriori} investigation reveals an intriguing temporal coincidence of neutrino, radio, and $\gamma$-ray flares of the J0242+1101 blazar at a $p=0.5\%$ ($2.9\sigma$ in the two-sided convention) level. Altogether, the results presented here suggest a possible connection of neutrino candidates detected by the ANTARES telescope with radio-bright blazars.

Published
2023
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55. Prospects for combined analyses of hadronic emission from $\gamma$-ray sources in the Milky Way with CTA and KM3NeT

Author

Unbehaun, T., Mohrmann, L., Funk, S., Aiello, S., Albert, A., Garre, S. Alves, Aly, Z., Ambrosone, A., Ameli, F., Andre, M., Androutsou, E., Anghinolfi, M., Anguita, M., Aphecetche, L., Ardid, M., Ardid, S., Atmani, H., Aublin, J., Bagatelas, C., Bailly-Salins, L., Bardačová, Z., Baret, B., Pree, S. Basegmez du, Becherini, Y., Bendahman, M., Benfenati, F., Benhassi, M., Benoit, D. M., Berbee, E., Bertin, V., Biagi, S., Boettcher, M., Cabo, M. Bou, Boumaaza, J., Bouta, M., Bouwhuis, M., Bozza, C., Bozza, R. M., Brânzaş, H., Bretaudeau, F., Bruijn, R., Brunner, J., Bruno, R., Buis, E., Buompane, R., Busto, J., Caiffi, B., Calvo, D., Campion, S., Capone, A., Carenini, F., Carretero, V., Cartraud, T., Castaldi, P., Cecchini, V., Celli, S., Cerisy, L., Chabab, M., Chadolias, M., Chen, A., Cherubini, S., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Coniglione, R., Coyle, P., Creusot, A., Cruz, A., Cuttone, G., Dallier, R., Darras, Y., De Benedittis, A., De Martino, B., Decoene, V., Del Burgo, R., Di Mauro, L. S., Di Palma, I., Díaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Donzaud, C., Dornic, D., Dörr, M., Drakopoulou, E., Drouhin, D., Dvornický, R., Eberl, T., Eckerová, E., Eddymaoui, A., van Eeden, T., Eff, M., van Eijk, D., Bojaddaini, I. El, Hedri, S. El, Enzenhöfer, A., Ferrara, G., Filipović, M. D., Filippini, F., Fusco, L. A., Gabriel, J., Gal, T., Méndez, J. García, Soto, A. Garcia, Oliver, C. Gatius, Geißelbrecht, N., Ghaddari, H., Gialanella, L., Gibson, B. K., Giorgio, E., Girardi, A., Goos, I., Gozzini, S. R., Gracia, R., Graf, K., Guderian, D., Guidi, C., Guillon, B., Gutiérrez, M., van Haren, H., Heijboer, A., Hekalo, A., Hennig, L., Hernández-Rey, J. J., Huang, F., Ibnsalih, W. Idrissi, Illuminati, G., James, C. W., de Jong, M., de Jong, P., Jung, B. J., Kalaczyński, P., Kalekin, O., Katz, U. F., Chowdhury, N. R. Khan, Khatun, A., Kistauri, G., van der Knaap, F., Kouchner, A., Kulikovskiy, V., Kvatadze, R., Labalme, M., Lahmann, R., Larosa, G., Lastoria, C., Lazo, A., Stum, S. Le, Lehaut, G., Leonora, E., Lessing, N., Levi, G., Clark, M. Lindsey, Longhitano, F., Majumdar, J., Malerba, L., Mańczak, J., Manfreda, A., Marconi, M., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Marzaioli, F., Mastrodicasa, M., Mastroianni, S., Miccichè, S., Miele, G., Migliozzi, P., Migneco, E., Mijakowski, P., Mitsou, M. L., Mollo, C. M., Morales-Gallegos, L., Morley-Wong, C., Mosbrugger, A., Moussa, A., Mateo, I. Mozun, Muller, R., Musone, M. R., Musumeci, M., Nauta, L., Navas, S., Nayerhoda, A., Nicolau, C. A., Nkosi, B., Fearraigh, B. Ó, Oliviero, V., Orlando, A., Oukacha, E., González, J. Palacios, Papalashvili, G., Gomez, E. J. Pastor, Păun, A. M., Păvălaş, G. E., Martínez, S. Peña, Perrin-Terrin, M., Perronnel, J., Pestel, V., Pestes, R., Piattelli, P., Poirè, C., Popa, V., Pradier, T., Pulvirenti, S., Quéméner, G., Quiroz, C., Rahaman, U., Randazzo, N., Razzaque, S., Rea, I. C., Real, D., Reck, S., Riccobene, G., Robinson, J., Romanov, A., Roscilli, L., Saina, A., Greus, F. Salesa, Samtleben, D. F. E., Losa, A. Sánchez, Sanguineti, M., Santonastaso, C., Santonocito, D., Sapienza, P., Schnabel, J., Schneider, M. F., Schumann, J., Schutte, H. M., Seneca, J., Sennan, N., Setter, B., Sgura, I., Shanidze, R., Shitov, Y., Šimkovic, F., Simonelli, A., Sinopoulou, A., Smirnov, M. V., Spisso, B., Spurio, M., Stavropoulos, D., Štekl, I., Taiuti, M., Tayalati, Y., Tedjditi, H., Thiersen, H., Melo, I. Tosta e, Trocme, B., Tsagkli, S., Tsourapis, V., Tzamariudaki, E., Vacheret, A., Valsecchi, V., Van Elewyck, V., Vannoye, G., Vasileiadis, G., de Sola, F. Vazquez, Verilhac, C., Veutro, A., Viola, S., Vivolo, D., Warnhofer, H., Wilms, J., de Wolf, E., Yousfi, T., Zarpapis, G., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zúñiga, J., and Zywucka, N.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The Cherenkov Telescope Array and the KM3NeT neutrino telescopes are major upcoming facilities in the fields of $\gamma$-ray and neutrino astronomy, respectively. Possible simultaneous production of $\gamma$ rays and neutrinos in astrophysical accelerators of cosmic-ray nuclei motivates a combination of their data. We assess the potential of a combined analysis of CTA and KM3NeT data to determine the contribution of hadronic emission processes in known Galactic $\gamma$-ray emitters, comparing this result to the cases of two separate analyses. In doing so, we demonstrate the capability of Gammapy, an open-source software package for the analysis of $\gamma$-ray data, to also process data from neutrino telescopes. For a selection of prototypical $\gamma$-ray sources within our Galaxy, we obtain models for primary proton and electron spectra in the hadronic and leptonic emission scenario, respectively, by fitting published $\gamma$-ray spectra. Using these models and instrument response functions for both detectors, we employ the Gammapy package to generate pseudo data sets, where we assume 200 hours of CTA observations and 10 years of KM3NeT detector operation. We then apply a three-dimensional binned likelihood analysis to these data sets, separately for each instrument and jointly for both. We find that the largest benefit of the combined analysis lies in the possibility of a consistent modelling of the $\gamma$-ray and neutrino emission. Assuming a purely leptonic scenario as input, we obtain, for the most favourable source, an average expected 68% credible interval that constrains the contribution of hadronic processes to the observed $\gamma$-ray emission to below 15%., Comment: 20 pages, 16 figures. v2: Matches version published in EPJC

Published
2023
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56. Unraveling the Effects of Dense Medium on a Near to Bohm-Limit Acceleration in Kepler's SNR

Author

Sapienza, Vincenzo, Miceli, Marco, Petruk, Oleh, Bamba, Aya, Orlando, Salvatore, Bocchino, Fabrizio, and Peres, Giovanni

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The maximum energy of electrons accelerated by supernova remnants (SNR) is typically limited by radiative losses. In this scenario, the synchrotron cooling time scale is equal to the acceleration time scale. On the other hand, the low propagation speed of a shock in a dense medium is expected to result in an extended acceleration time scale, thus inducing a decrease in the maximum electron energy for a given SNR age and in the X-ray nonthermal flux. The young Kepler's SNR shows an enhanced efficiency of the acceleration process, which is close to the Bohm limit in the north of its shell, where the shock is slowed down by a dense circumstellar medium. Conversely, in the south, where no interaction with a dense medium is evident and the shock speed is high, the acceleration proceeds with a higher Bohm factor. To investigate this scenario, we studied the temporal evolution of the non-thermal emission, taking advantage of two Chandra X-ray observations of Kepler's SNR (performed in 2006 and 2014). We analyzed the spectra of different filaments both in the north and south of the shell, and measured their proper motion. We found a region with low shock velocity where we measured a significant decrease in flux from 2006 to 2014. This could be the first evidence of fading synchrotron emission in Kepler's SNR. This result suggests that under a certain threshold of shock speed the acceleration process could exit the loss-limited regime., Comment: Presented at the 38th International Cosmic Ray Conference (ICRC 2023), 8 pages, 2 figures, 2 tables

Published
2023
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57. Nonlinear dielectric epsilon near-zero hybrid nanogap antennas

Author

Tirole, Romain, Tilmann, Benjamin, Menezes, Leonardo de S., Vezzoli, Stefano, Sapienza, Riccardo, and Maier, Stefan A.

Subjects
Physics - Optics
Abstract

High-index Mie-resonant dielectric nanostructures provide a new framework to manipulate light at the nanoscale. In particular their local field confinement together with their inherently low losses at frequencies below their band-gap energy allows to efficiently boost and control linear and nonlinear optical processes. Here, we investigate nanoantennas composed of a thin indium-tin oxide layer in the center of a dielectric Gallium Phosphide nanodisk. While the linear response is similar to that of a pure GaP nanodisk, we show that the second and third-harmonic signals of the nanogap antenna are boosted at resonance. Linear and nonlinear finite-difference time-domain simulations show that the high refractive index contrast leads to strong field confinement inside the antenna's ITO layer. Measurement of ITO and GaP nonlinear susceptibilities deliver insight on how to engineer nonlinear nanogap antennas for higher efficiencies for future nanoscale devices., Comment: main: 18 pages, 4 figues, supplemental: 8 pages, 4 figures, 1 table

Published
2023

58. Magnetic Field Draping in Induced Magnetospheres: Evidence from the MAVEN Mission to Mars

Author

Azari, A. R., Abrahams, E., Sapienza, F., Mitchell, D. L., Biersteker, J., Xu, S., Bowers, C., Pérez, F., DiBraccio, G. A., Dong, Y., and Curry, S.

Subjects
Physics - Space Physics, Astrophysics - Earth and Planetary Astrophysics, Statistics - Applications
Abstract

The Mars Atmosphere and Volatile EvolutioN (MAVEN) mission has been orbiting Mars since 2014 and now has over 10,000 orbits which we use to characterize Mars' dynamic space environment. Through global field line tracing with MAVEN magnetic field data we find an altitude dependent draping morphology that differs from expectations of induced magnetospheres in the vertical ($\hat Z$ Mars Sun-state, MSO) direction. We quantify this difference from the classical picture of induced magnetospheres with a Bayesian multiple linear regression model to predict the draped field as a function of the upstream interplanetary magnetic field (IMF), remanent crustal fields, and a previously underestimated induced effect. From our model we conclude that unexpected twists in high altitude dayside draping ($>$800 km) are a result of the IMF component in the $\pm \hat X$ MSO direction. We propose that this is a natural outcome of current theories of induced magnetospheres but has been underestimated due to approximations of the IMF as solely $\pm \hat Y$ directed. We additionally estimate that distortions in low altitude ($<$800 km) dayside draping along $\hat Z$ are directly related to remanent crustal fields. We show dayside draping traces down tail and previously reported inner magnetotail twists are likely caused by the crustal field of Mars, while the outer tail morphology is governed by an induced response to the IMF direction. We conclude with an updated understanding of induced magnetospheres which details dayside draping for multiple directions of the incoming IMF and discuss the repercussions of this draping for magnetotail morphology., Comment: Accepted in Journal of Geophysical Research: Space Physics

Published
2023
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59. Embedded Software of the KM3NeT Central Logic Board

Author

Aiello, S., Albert, A., Garre, S. Alves, Aly, Z., Ambrosone, A., Ameli, F., Andre, M., Androutsou, E., Anghinolfi, M., Anguita, M., Aphecetche, L., Ardid, M., Ardid, S., Atmani, H., Aublin, J., Bagatelas, C., Bailly-Salins, L., Bardačová, Z., Baret, B., Pree, S. Basegmez du, Becherini, Y., Bendahman, M., Benfenati, F., Benhassi, M., Benoit, D. M., Berbee, E., Bertin, V., van Beveren, V., Biagi, S., Boettcher, M., Boumaaza, J., Bouta, M., Bouwhuis, M., Bozzaa, C., Bozza, R. M., Brânzaşa, H., Bretaudeau, F., Bruijn, R., Brunner, J., Bruno, R., Buisa, E., Buompane, R., Busto, J., Caiffi, B., Calvo, D., Campion, S., Capone, A., Carenini, F., Carretero, V., Cartraud, T., Castaldia, P., Cecchini, V., Celli, S., Ceris, L., Chabab, M., Chadolia, M., Chen, A., Cherubini, S., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Coniglione, R., Coyle, P., Creusot, A., Cruza, A., Cuttone, G., Dallier, R., Darrasa, Y., De Beneditti, A., De Martino, B., Decoene, V., Del Burgo, R., Di Mauro, L. S., Di Palma, I., Díaz, A. F., Diego-Tortosa, D., Distefano, C., Domia, A., Donzaud, C., Dornic, D., Dörra, M., Drakopoulou, E., Drouhin, D., Dvornický, R., Eberla, T., Eckerov\', E., Eddymaoui, A., van Eeden, T., Effa, M., van Eijk, D., Bojaddaini, I. El, Hedri, S. El, Enzenhöfer, A., Ferrara, G., Filipović, M. D., Filippini, F., Fusco, L. A., Gabella, O., Gabriela, J., Gagliardini, S., Gala, T., Méndez, J. García, Soto, A. Garcia, Oliver, C. Gatius, Geißelbrecht, N., Ghaddari, H., Gialanella, L., Gibson, B. K., Giorgio, E., Girardi, A., Goos, I., Goupilliere, D., Gozzinic, S. R., Gracia, R., Graf, K., Guidia, C., Guillon, B., Gutiérrez, M., van Haren, H., Heijboer, A., Hekalo, A., Hennig, L., Hernández-Rey, J. J., Huang, F., Ibnsalih, W. Idrissi, Illuminati, G., Jamesa, C. W., Jansweijer, P., de Jongat, M., de Jong, P., Jung, B. J., Kalaczyński, P., Kalekin, O., Katz, U. F., Chowdhury, N. R. Khan, Khatun, A., Kistauri, G., Kopper, C., Kouchner, A., Kulikovskiy, V., Kvatadzea, R., Labalme, M., Lahmann, R., Larosa, G., Lastoria, C., Lazo, A., Stum, S. Le, Lehaut, G., Leonora, E., Lessing, N., Levi, G., Clark, M. Lindsey, Longhitano, F., Majumdar, J., Malerba, L., Mamedov, F., Mańczakc, J., Manfred, A., Marconi, M., Margiott, A., Marinelli, A., Markou, C., Martin, L., Martínez-Mora, J. A., Marzaioli, F., Mastrodicasa, M., Mastroianni, S., Miccichè, S., Miele, G., Migliozzi, P., Migneco, E., Minutoli, S., Mitsou, M. L., Mollo, C. M., Morales-Gallegos, L., Morley-Wonga, C., Mosbruggera, A., Moussa, A., Mateo, I. Mozun, Muller, R., Musone, M. R., Musumeci, M., Nauta, L., Navas, S., Nayerhoda, A., Nicola, C. A., Nkosi, B., Fearraigha, B. Ó, Oliviero, V., Orlando, A., Oukach, E., González, J. Palacios, Papalashvilia, G., Gomez, E. J. Pastor, Păun, A. M., Păvălaş, G. E., Martínez, S. Peña, Perrin-Terrind, M., Perronnel, J., Pestela, V., Pestes, R., Piattelli, P., Poirè, C., Popa, V., Pradier, T., Pulvirenti, S., Quéméner, G., Quiroz, C., Rahaman, U., Randazzo, N., Razzaqueb, S., Rea, I. C., Real, D., Reck, S., Riccobene, G., Robinson, J., Romanova, A., Saina, A., Greus, F. Salesa, Samtleben, D. F. E., Losa, A. Sánchez, Sanguineti, M., Santonastaso, C., Santonocito, D., Sapienza, P., Scarpetta, Y., Schnabel, J., Schneider, M. F., Schumann, J., Schutte, H. M., Seneca, J., Setter, B., Sgura, I., Shanidze, R., Shitov, Y., Šimkovic, F., Simonelli, A., Sinopoulou, A., Smirnov, M. V., Spisso, B., Spurio, M., Stavropoulos, D., Štekl, I., Taiuti, M., Tayalati, Y., Tedjditi, H., Thiersen, H., Melo, I. Tosta e, Trocme, B., Tsagkli, S., Tsourapis, V., Tzamariudaki, E., Vacheret, A., Valsecchi, V., Vannoye, V. Van Elewyck G., Vasileiadisa, G., de Sola, F. Vazquez, Verilhac, C., Veutro, A., Viola, S., Vivolo, D., Warnhofer, H., Wilmsb, J., de Wolf, E., Yepes-Ramirez, H., Zarpapis, G., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zúñiga, J., and Zywucka, N.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

The KM3NeT Collaboration is building and operating two deep sea neutrino telescopes at the bottom of the Mediterranean Sea. The telescopes consist of latices of photomultiplier tubes housed in pressure-resistant glass spheres, called digital optical modules and arranged in vertical detection units. The two main scientific goals are the determination of the neutrino mass ordering and the discovery and observation of high-energy neutrino sources in the Universe. Neutrinos are detected via the Cherenkov light, which is induced by charged particles originated in neutrino interactions. The photomultiplier tubes convert the Cherenkov light into electrical signals that are acquired and timestamped by the acquisition electronics. Each optical module houses the acquisition electronics for collecting and timestamping the photomultiplier signals with one nanosecond accuracy. Once finished, the two telescopes will have installed more than six thousand optical acquisition nodes, completing one of the more complex networks in the world in terms of operation and synchronization. The embedded software running in the acquisition nodes has been designed to provide a framework that will operate with different hardware versions and functionalities. The hardware will not be accessible once in operation, which complicates the embedded software architecture. The embedded software provides a set of tools to facilitate remote manageability of the deployed hardware, including safe reconfiguration of the firmware. This paper presents the architecture and the techniques, methods and implementation of the embedded software running in the acquisition nodes of the KM3NeT neutrino telescopes.

Published
2023

60. Atmospheric muons measured with the KM3NeT detectors in comparison with updated numeric predictions

Author

Aiello, S., Albert, A., Alshamsi, M., Alves Garre, S., Ambrosone, A., Ameli, F., Andre, M., Androutsou, E., Anguita, M., Aphecetche, L., Ardid, M., Ardid, S., Arsenic, A., Atmani, H., Aublin, J., Badaracco, F., Bailly-Salins, L., Bardačová, Z., Baret, B., Bariego-Quintana, A., Pree, S. Basegmez du, Becherini, Y., Bendahman, M., Benfenati, F., Benhassi, M., Benoit, D. M., Berbee, E., Bertin, V., Biagi, S., Boettcher, M., Bonanno, D., Boumaaza, J., Bouta, M., Bouwhuis, M., Bozza, C., Bozza, R. M., Brânzaş, H., Bretaudeau, F., Breuhaus, M., Bruijn, R., Brunner, J., Bruno, R., Buis, E., Buompane, R., Busto, J., Caiffi, B., Calvo, D., Campion, S., Capone, A., Carenini, F., Carretero, V., Cartraud, T., Castaldi, P., Cecchini, V., Celli, S., Cerisy, L., Chabab, M., Chadolias, M., Chen, A., Cherubini, S., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Condorelli, A., Coniglione, R., Coyle, P., Creusot, A., Cuttone, G., Dallier, R., Darras, Y., De Benedittis, A., De Martino, B., Decoene, V., Del Burgo, R., Del Rosso, I., Mauro, L. S. Di, Di Palma, I., Díaz, A. F., Diaz, C., Diego-Tortosa, D., Distefano, C., Domi, A., Donzaud, C., Dornic, D., Dörr, M., Drakopoulou, E., Drouhin, D., Ducoin, J.-G., Dvornický, R., Eberl, T., Eckerová, E., Eddymaoui, A., van Eeden, T., Eff, M., van Eijk, D., El Bojaddaini, I., El Hedri, S., Enzenhöfer, A., Ferrara, G., Filipović, M. D., Filippini, F., Franciotti, D., Fusco, L. A., Gagliardini, S., Gal, T., Méndez, J. García, Soto, A. Garcia, Oliver, C. Gatius, Geißelbrecht, N., Ghaddari, H., Gialanella, L., Gibson, B. K., Giorgio, E., Goos, I., Goswami, P., Gozzini, S. R., Gracia, R., Graf, K., Guidi, C., Guillon, B., Gutiérrez, M., Haack, C., van Haren, H., Heijboer, A., Hekalo, A., Hennig, L., Hernández-Rey, J. J., Ibnsalih, W. Idrissi, Illuminati, G., Joly, D., de Jong, M., de Jong, P., Jung, B. J., Kalaczyński, P., Kalekin, O., Katz, U. F., Khatun, A., Kistauri, G., Kopper, C., Kouchner, A., Kueviakoe, V., Kulikovskiy, V., Kvatadze, R., Labalme, M., Lahmann, R., Larosa, G., Lastoria, C., Lazo, A., Le Stum, S., Lehaut, G., Leonora, E., Lessing, N., Levi, G., Longhitano, F., Magnani, F., Majumdar, J., Malerba, L., Mamedov, F., Mańczak, J., Manfreda, A., Marconi, M., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Marzaioli, F., Mastrodicasa, M., Mastroianni, S., Miccichè, S., Miele, G., Migliozzi, P., Migneco, E., Mitsou, M. L., Mollo, C. M., Morales-Gallegos, L., Moretti, G., Moussa, A., Mateo, I. Mozun, Muller, R., Musone, M. R., Musumeci, M., Navas, S., Nayerhoda, A., Nicolau, C. A., Nkosi, B., Fearraigh, B. Ó., Oliviero, V., Orlando, A., Oukacha, E., Paesani, D., González, J. Palacios, Papalashvili, G., Parisi, V., Pastor Gomez, E. J., Păun, A. M., Păvălaş, G. E., Pelegris, I., Peña Martínez, S., Perrin-Terrin, M., Perronnel, J., Pestel, V., Pestes, R., Piattelli, P., Poirè, C., Popa, V., Pradier, T., Prado, J., Pulvirenti, S., Quiroz-Rangel, C. A., Rahaman, U., Randazzo, N., Razzaque, S., Rea, I. C., Real, D., Riccobene, G., Robinson, J., Romanov, A., Šaina, A., Greus, F. Salesa, Samtleben, D. F. E., Losa, A. Sánchez, Sanfilippo, S., Sanguineti, M., Santonastaso, C., Santonocito, D., Sapienza, P., Schnabel, J., Schumann, J., Schutte, H. M., Seneca, J., Sennan, N., Setter, B., Sgura, I., Shanidze, R., Sharma, A., Shitov, Y., Šimkovic, F., Simonelli, A., Sinopoulou, A., Smirnov, M. V., Spisso, B., Spurio, M., Stavropoulos, D., Štekl, I., Taiuti, M., Tayalati, Y., Thiersen, H., Melo, I. Tosta e, Tragia, E., Trocmé, B., Tsourapis, V., Tudorache, A., Tzamariudaki, E., Vacheret, A., Melchor, A. Valer, Valsecchi, V., Elewyck, V. Van, Vannoye, G., Vasileiadis, G., de Sola, F. Vazquez, Veutro, A., Viola, S., Vivolo, D., Wilms, J., de Wolf, E., Yepes-Ramirez, H., Yvon, I., Zarpapis, G., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zúñiga, J., and Zywucka, N.

Published
2024
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64. Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI) (AltoidaML)

Author

Greek Alzheimer's Association and Related Disorders, University of Roma La Sapienza, IRCCS Centro San Giovanni di Dio Fatebenefratelli, Neuromed IRCCS, Scripps Health, Global Brain Health Institute (GBHI), Takeda Pharmaceuticals International, Inc., Research Center on Computational Biomarkers (RCCBM), BiHELab - Bioinformatics and Human Electrophysiology Lab, Fundacion Clinic per a la Recerca Biomédica, University of Dublin, Trinity College, University of Barcelona, EIT Health, Klinik Hirslanden, Zurich, and Center for BrainHealth - The University of Texas at Dallas

Published
2024

72. Driving Pressure During General Anesthesia for Open Abdominal Surgery (DESIGNATION)

Author

Amsterdam UMC, location VUmc, Noord West Ziekenhuizen location Alkmaar, University Medical Center Groningen, Radboud University Medical Center, HagaZiekenhuis, Rijnstate Hospital, Medical Center Haaglanden, Bernhoven Hospital, Onze Lieve Vrouwe Gasthuis, Albert Schweitzer Hospital, Medical Centre Leeuwarden, Leiden University Medical Center, Maastricht University Medical Center, Martini Hospital Groningen, Erasmus Medical Center, Spaarne Gasthuis, University Hospital Carl Gustav Carus, Bermanntrost BG Klinikum Halle, Heinrich-Heine University, Duesseldorf, Ospedale Policlinico San Martino, Jeroen Bosch Ziekenhuis, Meander Medical Center, Isala, Alrijne Hospital, Antoni van Leeuwenhoek Ziekenhuis, Medisch Spectrum Twente, Campus Bio-Medico University, Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale, University of Roma La Sapienza, University of Campania "Luigi Vanvitelli", Hospital Universitario La Fe, Medical University Innsbruck, and Prof. Dr. Marcus J. Schultz, Principal Investigator

Published
2024

73. Quantitative Analysis of Paleomagnetic Sampling Strategies

Author

Sapienza, F, Gallo, LC, Zhang, Y, Vaes, B, Domeier, M, and Swanson‐Hysell, NL

Subjects
Earth Sciences, Geology, Generic health relevance, paleomagnetism, paleopole estimation, secular variation, error quantification, Geochemistry, Geophysics
Abstract

Sampling strategies used in paleomagnetic studies play a crucial role in dictating the accuracy of our estimates of properties of the ancient geomagnetic field. However, there has been little quantitative analysis of optimal paleomagnetic sampling strategies and the community has instead defaulted to traditional practices that vary between laboratories. In this paper, we quantitatively evaluate the accuracy of alternative paleomagnetic sampling strategies through numerical experiments and an associated analytical framework. Our findings demonstrate a strong correspondence between the accuracy of an estimated paleopole position and the number of sites or independent readings of the time-varying paleomagnetic field, whereas larger numbers of in-site samples have a dwindling effect. This remains true even when a large proportion of the sample directions are spurious. This approach can be readily achieved in sedimentary sequences by distributing samples stratigraphically, considering each sample as an individual site. However, where the number of potential independent sites is inherently limited the collection of additional in-site samples can improve the accuracy of the paleopole estimate (although with diminishing returns with increasing samples per site). Where an estimate of the magnitude of paleosecular variation is sought, multiple in-site samples should be taken, but the optimal number is dependent on the expected fraction of outliers. The use of filters based on angular distance helps the accuracy of paleopole estimation, but leads to inaccurate estimates of paleosecular variation. We provide both analytical formulas and a series of interactive Jupyter notebooks allowing optimal sampling strategies to be developed from user-informed expectations.

Published
2023

74. APL special topic: Time modulated metamaterials

Author

Sapienza, Riccardo, Shcherbakov, Maxim, Faccio, Daniele, Cui, Tie Jun, and Caglayan, Humeyra

Subjects
Engineering, Physical Sciences, Technology, Applied Physics, Physical sciences
Published
2023

75. Second harmonic generation at a time-varying interface

Author

Romain Tirole, Stefano Vezzoli, Dhruv Saxena, Shu Yang, T. V. Raziman, Emanuele Galiffi, Stefan A. Maier, John B. Pendry, and Riccardo Sapienza

Subjects
Science
Abstract

Abstract Time-varying metamaterials rely on large and fast changes of the linear permittivity. Beyond the linear terms, however, the effect of a non-perturbative modulation of the medium on harmonic generation remains largely unexplored. In this work, we study second harmonic generation at an optically pumped time-varying interface between air and a 310 nm Indium Tin Oxide film. We observe a modulation contrast at the second harmonic wavelength up to 93% for a pump intensity of 100 GW/cm2, leading to large frequency broadening and shift. We experimentally demonstrate that a significant contribution to the enhancement comes from the temporal modulation of the second order nonlinear susceptibility. Moreover, we show the frequency-modulated spectra resulting from single and double-slit time diffraction could be exploited for enhanced optical computing and sensing, enabling broadband time-varying effects on the harmonic signal and extending the application of Epsilon-Near-Zero materials to the visible range.

Published
2024
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76. Astronomy potential of KM3NeT/ARCA

Author

KM3NeT Collaboration, S. Aiello, A. Albert, M. Alshamsi, S. Alves Garre, Z. Aly, A. Ambrosone, F. Ameli, M. Andre, E. Androutsou, M. Anguita, L. Aphecetche, M. Ardid, S. Ardid, H. Atmani, J. Aublin, F. Badaracco, L. Bailly-Salins, Z. Bardačová, B. Baret, A. Bariego-Quintana, A. Baruzzi, S. Basegmez du Pree, Y. Becherini, M. Bendahman, F. Benfenati, M. Benhassi, D. M. Benoit, E. Berbee, V. Bertin, S. Biagi, M. Boettcher, D. Bonanno, J. Boumaaza, M. Bouta, M. Bouwhuis, C. Bozza, R. M. Bozza, H. Brânzaş, F. Bretaudeau, M. Breuhaus, R. Bruijn, J. Brunner, R. Bruno, E. Buis, R. Buompane, J. Busto, B. Caiffi, D. Calvo, S. Campion, A. Capone, F. Carenini, V. Carretero, T. Cartraud, P. Castaldi, V. Cecchini, S. Celli, L. Cerisy, M. Chabab, M. Chadolias, A. Chen, S. Cherubini, T. Chiarusi, M. Circella, R. Cocimano, J. A. B. Coelho, A. Coleiro, R. Coniglione, P. Coyle, A. Creusot, G. Cuttone, R. Dallier, Y. Darras, A. De Benedittis, B. De Martino, V. Decoene, R. Del Burgo, I. Del Rosso, L. S. Di Mauro, I. Di Palma, A. F. Díaz, C. Diaz, D. Diego-Tortosa, C. Distefano, A. Domi, C. Donzaud, D. Dornic, M. Dörr, E. Drakopoulou, D. Drouhin, J.-G. Ducoin, R. Dvornický, T. Eberl, E. Eckerová, A. Eddymaoui, T. van Eeden, M. Eff, D. van Eijk, I. El Bojaddaini, S. El Hedri, A. Enzenhöfer, G. Ferrara, M. D. Filipović, F. Filippini, D. Franciotti, L. A. Fusco, J. Gabriel, S. Gagliardini, T. Gal, J. García Méndez, A. Garcia Soto, C. Gatius Oliver, N. Geißelbrecht, H. Ghaddari, L. Gialanella, B. K. Gibson, E. Giorgio, I. Goos, P. Goswami, D. Goupilliere, S. R. Gozzini, R. Gracia, K. Graf, C. Guidi, B. Guillon, M. Gutiérrez, H. van Haren, A. Heijboer, A. Hekalo, L. Hennig, J. J. Hernández-Rey, W. Idrissi Ibnsalih, G. Illuminati, M. de Jong, P. de Jong, B. J. Jung, P. Kalaczyński, O. Kalekin, U. F. Katz, G. Kistauri, C. Kopper, A. Kouchner, V. Kueviakoe, V. Kulikovskiy, R. Kvatadze, M. Labalme, R. Lahmann, G. Larosa, C. Lastoria, A. Lazo, S. Le Stum, G. Lehaut, E. Leonora, N. Lessing, G. Levi, M. Lindsey Clark, F. Longhitano, F. Magnani, J. Majumdar, L. Malerba, F. Mamedov, J. Mańczak, A. Manfreda, M. Marconi, A. Margiotta, A. Marinelli, C. Markou, L. Martin, J. A. Martínez-Mora, F. Marzaioli, M. Mastrodicasa, S. Mastroianni, S. Miccichè, G. Miele, P. Migliozzi, E. Migneco, M. L. Mitsou, C. M. Mollo, L. Morales-Gallegos, M. Morga, A. Moussa, I. Mozun Mateo, R. Muller, M. R. Musone, M. Musumeci, S. Navas, A. Nayerhoda, C. A. Nicolau, B. Nkosi, B. Ó Fearraigh, V. Oliviero, A. Orlando, E. Oukacha, D. Paesani, J. Palacios González, G. Papalashvili, V. Parisi, E. J. Pastor Gomez, A. M. Păun, G. E. Păvălaş, I. Pelegris, S. Peña Martínez, M. Perrin-Terrin, J. Perronnel, V. Pestel, R. Pestes, P. Piattelli, C. Poirè, V. Popa, T. Pradier, J. Prado, S. Pulvirenti, C. A. Quiroz-Rangel, U. Rahaman, N. Randazzo, R. Randriatoamanana, S. Razzaque, I. C. Rea, D. Real, G. Riccobene, J. Robinson, A. Romanov, A. Šaina, F. Salesa Greus, D. F. E. Samtleben, A. Sánchez Losa, S. Sanfilippo, M. Sanguineti, C. Santonastaso, D. Santonocito, P. Sapienza, J. Schnabel, J. Schumann, H. M. Schutte, J. Seneca, N. Sennan, B. Setter, I. Sgura, R. Shanidze, A. Sharma, Y. Shitov, F. Šimkovic, A. Simonelli, A. Sinopoulou, M. V. Smirnov, B. Spisso, M. Spurio, D. Stavropoulos, I. Štekl, M. Taiuti, Y. Tayalati, H. Thiersen, I. Tosta e Melo, E. Tragia, B. Trocmé, V. Tsourapis, A. Tudorache, E. Tzamariudaki, A. Vacheret, A. Valer Melchor, V. Valsecchi, V. Van Elewyck, G. Vannoye, G. Vasileiadis, F. Vazquez de Sola, C. Verilhac, A. Veutro, S. Viola, D. Vivolo, J. Wilms, E. de Wolf, H. Yepes-Ramirez, G. Zarpapis, S. Zavatarelli, A. Zegarelli, D. Zito, J. D. Zornoza, J. Zúñiga, and N. Zywucka

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The KM3NeT/ARCA neutrino detector is currently under construction at 3500 m depth offshore Capo Passero, Sicily, in the Mediterranean Sea. The main science objectives are the detection of high-energy cosmic neutrinos and the discovery of their sources. Simulations were conducted for the full KM3NeT/ARCA detector, instrumenting a volume of 1 km $$^3$$ 3 , to estimate the sensitivity and discovery potential to point-like neutrino sources. This paper covers the reconstruction of track- and shower-like signatures, as well as the criteria employed for neutrino event selection. With an angular resolution below 0.1 $$^\circ $$ ∘ for tracks and under 2 $$^\circ $$ ∘ for showers, the sensitivity to point-like neutrino sources surpasses existing observed limits across the entire sky.

Published
2024
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77. Assessing the clinical utility of inertial sensors for home monitoring in Parkinson’s disease: a comprehensive review

Author

Stefano Sapienza, Olena Tsurkalenko, Marijus Giraitis, Alan Castro Mejia, Gelani Zelimkhanov, Isabel Schwaninger, and Jochen Klucken

Subjects
Neurology. Diseases of the nervous system, RC346-429
Abstract

Abstract This review screened 296 articles on wearable sensors for home monitoring of people with Parkinson’s Disease within the PubMed Database, from January 2017 to May 2023. A three-level maturity framework was applied for classifying the aims of 59 studies included: demonstrating technical efficacy, diagnostic sensitivity, or clinical utility. As secondary analysis, user experience (usability and patient adherence) was evaluated. The evidences provided by the studies were categorized and stratified according to the level of maturity. Our results indicate that approximately 75% of articles investigated diagnostic sensitivity, i.e. correlation of sensor-data with clinical parameters. Evidence of clinical utility, defined as improvement on health outcomes or clinical decisions after the use of the wearables, was found only in nine papers. A third of the articles included reported evidence of user experience. Future research should focus more on clinical utility, to facilitate the translation of research results within the management of Parkinson’s Disease.

Published
2024
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78. Atmospheric muons measured with the KM3NeT detectors in comparison with updated numeric predictions

Author

KM3NeT Collaboration, S. Aiello, A. Albert, M. Alshamsi, S. Alves Garre, A. Ambrosone, F. Ameli, M. Andre, E. Androutsou, M. Anguita, L. Aphecetche, M. Ardid, S. Ardid, A. Arsenic, H. Atmani, J. Aublin, F. Badaracco, L. Bailly-Salins, Z. Bardačová, B. Baret, A. Bariego-Quintana, S. Basegmez du Pree, Y. Becherini, M. Bendahman, F. Benfenati, M. Benhassi, D. M. Benoit, E. Berbee, V. Bertin, S. Biagi, M. Boettcher, D. Bonanno, J. Boumaaza, M. Bouta, M. Bouwhuis, C. Bozza, R. M. Bozza, H. Brânzaş, F. Bretaudeau, M. Breuhaus, R. Bruijn, J. Brunner, R. Bruno, E. Buis, R. Buompane, J. Busto, B. Caiffi, D. Calvo, S. Campion, A. Capone, F. Carenini, V. Carretero, T. Cartraud, P. Castaldi, V. Cecchini, S. Celli, L. Cerisy, M. Chabab, M. Chadolias, A. Chen, S. Cherubini, T. Chiarusi, M. Circella, R. Cocimano, J. A. B. Coelho, A. Coleiro, A. Condorelli, R. Coniglione, P. Coyle, A. Creusot, G. Cuttone, R. Dallier, Y. Darras, A. De Benedittis, B. De Martino, V. Decoene, R. Del Burgo, I. Del Rosso, L. S. Di Mauro, I. Di Palma, A. F. Díaz, C. Diaz, D. Diego-Tortosa, C. Distefano, A. Domi, C. Donzaud, D. Dornic, M. Dörr, E. Drakopoulou, D. Drouhin, J.-G. Ducoin, R. Dvornický, T. Eberl, E. Eckerová, A. Eddymaoui, T. van Eeden, M. Eff, D. van Eijk, I. El Bojaddaini, S. El Hedri, A. Enzenhöfer, G. Ferrara, M. D. Filipović, F. Filippini, D. Franciotti, L. A. Fusco, S. Gagliardini, T. Gal, J. García Méndez, A. Garcia Soto, C. Gatius Oliver, N. Geißelbrecht, H. Ghaddari, L. Gialanella, B. K. Gibson, E. Giorgio, I. Goos, P. Goswami, S. R. Gozzini, R. Gracia, K. Graf, C. Guidi, B. Guillon, M. Gutiérrez, C. Haack, H. van Haren, A. Heijboer, A. Hekalo, L. Hennig, J. J. Hernández-Rey, W. Idrissi Ibnsalih, G. Illuminati, D. Joly, M. de Jong, P. de Jong, B. J. Jung, P. Kalaczyński, O. Kalekin, U. F. Katz, A. Khatun, G. Kistauri, C. Kopper, A. Kouchner, V. Kueviakoe, V. Kulikovskiy, R. Kvatadze, M. Labalme, R. Lahmann, G. Larosa, C. Lastoria, A. Lazo, S. Le Stum, G. Lehaut, E. Leonora, N. Lessing, G. Levi, F. Longhitano, F. Magnani, J. Majumdar, L. Malerba, F. Mamedov, J. Mańczak, A. Manfreda, M. Marconi, A. Margiotta, A. Marinelli, C. Markou, L. Martin, F. Marzaioli, M. Mastrodicasa, S. Mastroianni, S. Miccichè, G. Miele, P. Migliozzi, E. Migneco, M. L. Mitsou, C. M. Mollo, L. Morales-Gallegos, G. Moretti, A. Moussa, I. Mozun Mateo, R. Muller, M. R. Musone, M. Musumeci, S. Navas, A. Nayerhoda, C. A. Nicolau, B. Nkosi, B. Ó. Fearraigh, V. Oliviero, A. Orlando, E. Oukacha, D. Paesani, J. Palacios González, G. Papalashvili, V. Parisi, E. J. Pastor Gomez, A. M. Păun, G. E. Păvălaş, I. Pelegris, S. Peña Martínez, M. Perrin-Terrin, J. Perronnel, V. Pestel, R. Pestes, P. Piattelli, C. Poirè, V. Popa, T. Pradier, J. Prado, S. Pulvirenti, C. A. Quiroz-Rangel, U. Rahaman, N. Randazzo, S. Razzaque, I. C. Rea, D. Real, G. Riccobene, J. Robinson, A. Romanov, A. Šaina, F. Salesa Greus, D. F. E. Samtleben, A. Sánchez Losa, S. Sanfilippo, M. Sanguineti, C. Santonastaso, D. Santonocito, P. Sapienza, J. Schnabel, J. Schumann, H. M. Schutte, J. Seneca, N. Sennan, B. Setter, I. Sgura, R. Shanidze, A. Sharma, Y. Shitov, F. Šimkovic, A. Simonelli, A. Sinopoulou, M. V. Smirnov, B. Spisso, M. Spurio, D. Stavropoulos, I. Štekl, M. Taiuti, Y. Tayalati, H. Thiersen, I. Tosta e Melo, E. Tragia, B. Trocmé, V. Tsourapis, A. Tudorache, E. Tzamariudaki, A. Vacheret, A. Valer Melchor, V. Valsecchi, V. Van Elewyck, G. Vannoye, G. Vasileiadis, F. Vazquez de Sola, A. Veutro, S. Viola, D. Vivolo, J. Wilms, E. de Wolf, H. Yepes-Ramirez, I. Yvon, G. Zarpapis, S. Zavatarelli, A. Zegarelli, D. Zito, J. D. Zornoza, J. Zúñiga, and N. Zywucka

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The measurement of the flux of muons produced in cosmic ray air showers is essential for the study of primary cosmic rays. Such measurements are important in extensive air shower detectors to assess the energy spectrum and the chemical composition of the cosmic ray flux, complementary to the information provided by fluorescence detectors. Detailed simulations of the cosmic ray air showers are carried out, using codes such as CORSIKA, to estimate the muon flux at sea level. These simulations are based on the choice of hadronic interaction models, for which improvements have been implemented in the post-LHC era. In this work, a deficit in simulations that use state-of-the-art QCD models with respect to the measurement deep underwater with the KM3NeT neutrino detectors is reported. The KM3NeT/ARCA and KM3NeT/ORCA neutrino telescopes are sensitive to TeV muons originating mostly from primary cosmic rays with energies around 10 TeV. The predictions of state-of-the-art QCD models show that the deficit with respect to the data is constant in zenith angle; no dependency on the water overburden is observed. The observed deficit at a depth of several kilometres is compatible with the deficit seen in the comparison of the simulations and measurements at sea level.

Published
2024
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80. Controlling lasing around Exceptional Points in Coupled Nanolasers

Author

Fischer, Anna, Raziman, T. V., Ng, Wai Kit, Clarysse, Jente, Dranczewski, Jakub, Saxena, Dhruv, Vezzoli, Stefano, Schmid, Heinz, Moselund, Kirsten, and Sapienza, Riccardo

Subjects
Physics - Optics
Abstract

Coupled nanolasers are of growing interest for on-chip optical computation and data transmission, which requires an understanding of how lasers interact to form complex systems. The non-Hermitian interaction between two coupled resonators, when excited selectively, can lead to parity-time symmetry, the formation of exceptional points, and subsequently spectral control and increased sensitivity. These investigations have been limited to pump energies close to the lasing threshold, and large or narrow-line lasers. Here, by programmable optical excitation we study two coupled nanolasers significantly above threshold, where mode instability plays an important role. We map the mode evolution around two exceptional points, and observe lasing gaps due to reversed pump dependence which compare well with nonlinear theory. Finally, the coupling can be exploited to control the lasing threshold and wavelength, and for frequency switching around the lasing gap. Controlled and integrated nanolasers constitutes a promising platform for future highly sensitive and programmable on-chip laser sources., Comment: 8 pages, 4 figures

Published
2023
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81. Graph model for multiple scattering in lithium niobate on insulator integrated photonic networks

Author

Wang, Xiyue Sissi, Savo, Romolo, Maeder, Andreas, Kaufmann, Fabian, Kellner, Jost, Morandi, Andrea, Rotter, Stefan, Sapienza, Riccardo, and Grange, Rachel

Subjects
Physics - Optics, Physics - Applied Physics
Abstract

We present a graph-based model for multiple scattering of light in integrated lithium niobate on insulator (LNOI) networks, which describes an open network of single-mode integrated waveguides with tunable scattering at the network nodes. We first validate the model at small scale with experimental LNOI resonator devices and show consistent agreement between simulated and measured spectral data. Then, the model is used to demonstrate a novel platform for on-chip multiple scattering in large-scale optical networks up to few hundred nodes, with tunable scattering behaviour and tailored disorder. Combining our simple graph-based model with material properties of LNOI, this platform creates new opportunities to control randomness in large optical networks.

Published
2023

82. Observations of the Crab Nebula and Pulsar with the Large-Sized Telescope Prototype of the Cherenkov Telescope Array

Author

Project, CTA-LST, Abe, H., Abe, K., Abe, S., Aguasca-Cabot, A., Agudo, I., Crespo, N. Alvarez, Antonelli, L. A., Aramo, C., Arbet-Engels, A., Arcaro, C., Artero, M., Asano, K., Aubert, P., Baktash, A., Bamba, A., Larriva, A. Baquero, Baroncelli, L., de Almeida, U. Barres, Barrio, J. A., Batkovic, I., Baxter, J., González, J. Becerra, Bernardini, E., Bernardos, M. I., Medrano, J. Bernete, Berti, A., Bhattacharjee, P., Biederbeck, N., Bigongiari, C., Bissaldi, E., Blanch, O., Bonnoli, G., Bordas, P., Borghese, A., Bulgarelli, A., Burelli, I., Buscemi, M., Cardillo, M., Caroff, S., Carosi, A., Cassol, F., Cauz, D., Ceribella, G., Chai, Y., Cheng, K., Chiavassa, A., Chikawa, M., Chytka, L., Cifuentes, A., Contreras, J. L., Cortina, J., Costantini, H., D'Amico, G., Dalchenko, M., De Angelis, A., de Lavergne, M. de Bony, De Lotto, B., de Menezes, R., Deleglise, G., Delgado, C., Mengual, J. Delgado, della Volpe, D., Dellaiera, M., Depaoli, D., Di Piano, A., Di Pierro, F., Di Tria, R., Di Venere, L., Díaz, C., Dominik, R. M., Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Elsässer, D., Emery, G., Escudero, J., Ramazani, V. Fallah, Ferrara, G., Ferrarotto, F., Fiasson, A., Coromina, L. Freixas, Fröse, S., Fukami, S., Fukazawa, Y., Garcia, E., López, R. Garcia, Gasbarra, C., Gasparrini, D., Geyer, F., Paiva, J. Giesbrecht, Giglietto, N., Giordano, F., Giro, E., Gliwny, P., Godinovic, N., Grau, R., Green, D., Green, J., Gunji, S., Hackfeld, J., Hadasch, D., Hahn, A., Hashiyama, K., Hassan, T., Hayashi, K., Heckmann, L., Heller, M., Llorente, J. Herrera, Hirotani, K., Hoffmann, D., Horns, D., Houles, J., Hrabovsky, M., Hrupec, D., Hui, D., Hütten, M., Iarlori, M., Imazawa, R., Inada, T., Inome, Y., Ioka, K., Iori, M., Ishio, K., Iwamura, Y., Jacquemont, M., Martinez, I. Jimenez, Jurysek, J., Kagaya, M., Karas, V., Katagiri, H., Kataoka, J., Kerszberg, D., Kobayashi, Y., Kong, A., Kubo, H., Kushida, J., Lainez, M., Lamanna, G., Lamastra, A., Flour, T. Le, Linhoff, M., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Lorini, A., Luque-Escamilla, P. L., Majumdar, P., Makariev, M., Mandat, D., Manganaro, M., Manicò, G., Mannheim, K., Mariotti, M., Marquez, P., Marsella, G., Martí, J., Martinez, O., Martínez, G., Martínez, M., Marusevec, P., Mas-Aguilar, A., Maurin, G., Mazin, D., Guillen, E. Mestre, Micanovic, S., Miceli, D., Miener, T., Miranda, J. M., Mirzoyan, R., Mizuno, T., Gonzalez, M. Molero, Molina, E., Montaruli, T., Monteiro, I., Moralejo, A., Morcuende, D., Morselli, A., Mrakovcic, K., Murase, K., Nagai, A., Nagataki, S., Nakamori, T., Nickel, L., Nievas, M., Nishijima, K., Noda, K., Nosek, D., Nozaki, S., Ohishi, M., Ohtani, Y., Oka, T., Okazaki, N., Okumura, A., Orito, R., Otero-Santos, J., Palatiello, M., Paneque, D., Pantaleo, F. R., Paoletti, R., Paredes, J. M., Pech, M., Pecimotika, M., Peresano, M., Pérez, A., Pietropaolo, E., Pirola, G., Plard, C., Podobnik, F., Poireau, V., Polo, M., Pons, E., Prandini, E., Prast, J., Principe, G., Priyadarshi, C., Prouza, M., Rando, R., Rhode, W., Ribó, M., Rizi, V., Fernandez, G. Rodriguez, Ruiz, J. E., Saito, T., Sakurai, S., Sanchez, D. A., Šarić, T., Sato, Y., Saturni, F. G., Schleicher, B., Schmuckermaier, F., Schubert, J. L., Schussler, F., Schweizer, T., Arroyo, M. Seglar, Silvia, R., Sitarek, J., Sliusar, V., Spolon, A., Strišković, J., Strzys, M., Suda, Y., Sunada, Y., Tajima, H., Takahashi, H., Takahashi, M., Takata, J., Takeishi, R., Tam, P. H. T., Tanaka, S. J., Tateishi, D., Tejedor, L. A., Temnikov, P., Terada, Y., Terauchi, K., Terzic, T., Teshima, M., Tluczykont, M., Tokanai, F., Torres, D. F., Travnicek, P., Truzzi, S., Tutone, A., Uhlrich, G., Vacula, M., Vallania, P., van Scherpenberg, J., Acosta, M. Vázquez, Verguilov, V., Viale, I., Vigliano, A., Vigorito, C. F., Vitale, V., Voutsinas, G., Vovk, I., Vuillaume, T., Walter, R., Will, M., Yamamoto, T., Yamazaki, R., Yoshida, T., Yoshikoshi, T., Zywucka, N., Bernloehr, K., Gueta, O., Kosack, K., Maier, G., Watson, J., Rijeka, University of, Physics, Department of, Rijeka, Croatia, Physics, Institute for Theoretical, Astrophysics, Würzburg, Universität, Nord, Campus Hubland, Würzburg, Germany, Physik, Institut für Theoretische, IV, Lehrstuhl, Plasma-Astroteilchenphysik, Bochum, Ruhr-Universität, Bochum, La Sapienza, INFN Sezione di Roma, Rome, Italy, ILANCE, Laboratory, CNRS - University of Tokyo International Research, Kashiwa, Chiba, Japan, Program, Physics, Science, Graduate School of Advanced, Engineering, University, Hiroshima, Hiroshima, Vergata, INFN Sezione di Roma Tor, Physics, Faculty of, Informatics, Applied, Lodz, University of, Lodz, Poland, Split, University of, FESB, Split, University, Yamagata, Yamagata, University, Tohoku, Institute, Astronomical, Aobaku, Sendai, Osijek, Josip Juraj Strossmayer University of, Osijek, dell'Aquila, INFN Dipartimento di Scienze Fisiche e Chimiche - Università degli Studi, Institute, Gran Sasso Science, L'Aquila, Oiwakecho, Kitashirakawa, Kyoto, Astronomy, Department of, Geneva, University of, Versoix, Switzerland, Sciences, Astronomical Institute of the Czech Academy of, Prague, Republic, Czech, Science, Faculty of, University, Ibaraki, Mito, Ibaraki, University, Waseda, Shinjuku, Tokyo, di Trieste, INFN Sezione, di Trieste, Università degli Studi, Trieste, INFN, di Siena, Università degli Studi, Fisiche, Dipartimento di Scienze, dell'Ambiente, della Terra e, di Fisica, Sezione, Siena, de Jaén, Escuela Politécnica Superior, de Jaén, Universidad, Lagunillas, Campus Las, Jaén, Spain, Physics, Saha Institute of Nuclear, Bidhannagar, Kolkata, India, Research, Institute for Nuclear, Energy, Nuclear, Sciences, Bulgarian Academy of, Sofia, Bulgaria, Sciences, FZU - Institute of Physics of the Czech Academy of, Praha, di Palermo, Dipartimento di Fisica e Chimica 'E. Segrè' Università degli Studi, Scienze, via delle, Palermo, de Electronica, Grupo, de Madrid, Universidad Complutense, Complutense, Av., Madrid, Physics, Department of Applied, Zagreb, University of, Zagreb, Center, Hiroshima Astrophysical Science, Higashi-Hiroshima, RIKEN, Physical, Institute of, Research, Chemical, Wako, Saitama, University, Charles, Particle, Institute of, Physics, Nuclear, Physics, Division of, Astronomy, Science, Graduate School of, University, Kyoto, Sakyo-ku, Research, Institute for Space-Earth Environmental, University, Nagoya, Chikusa-ku, Nagoya, Institute, Kobayashi-Maskawa, Particles, for the Origin of, Universe, the, Technology, Graduate School of, Industrial, Sciences, Social, University, Tokushima, Tokushima, Sciences, Department of Physical, University, Aoyama Gakuin, Fuchinobe, Sagamihara, Kanagawa, IRFU, CEA, Paris-Saclay, Université, Gif-sur-Yvette, France, University, Saitama, Sakura-ku, city, Saitama, di Torino, Dipartimento di Fisica - Universitá degli Studi, Torino, University, Konan, Kobe, Hyogo, Japan), Heidelberg, Zeuthen, Saclay, CEA, Merisiers, Orme des, and France)

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

CTA (Cherenkov Telescope Array) is the next generation ground-based observatory for gamma-ray astronomy at very-high energies. The Large-Sized Telescope prototype (LST-1) is located at the Northern site of CTA, on the Canary Island of La Palma. LSTs are designed to provide optimal performance in the lowest part of the energy range covered by CTA, down to $\simeq 20$ GeV. LST-1 started performing astronomical observations in November 2019, during its commissioning phase, and it has been taking data since then. We present the first LST-1 observations of the Crab Nebula, the standard candle of very-high energy gamma-ray astronomy, and use them, together with simulations, to assess the basic performance parameters of the telescope. The data sample consists of around 36 hours of observations at low zenith angles collected between November 2020 and March 2022. LST-1 has reached the expected performance during its commissioning period - only a minor adjustment of the preexisting simulations was needed to match the telescope behavior. The energy threshold at trigger level is estimated to be around 20 GeV, rising to $\simeq 30$ GeV after data analysis. Performance parameters depend strongly on energy, and on the strength of the gamma-ray selection cuts in the analysis: angular resolution ranges from 0.12 to 0.40 degrees, and energy resolution from 15 to 50%. Flux sensitivity is around 1.1% of the Crab Nebula flux above 250 GeV for a 50-h observation (12% for 30 minutes). The spectral energy distribution (in the 0.03 - 30 TeV range) and the light curve obtained for the Crab Nebula agree with previous measurements, considering statistical and systematic uncertainties. A clear periodic signal is also detected from the pulsar at the center of the Nebula., Comment: Accepted in ApJ. v3: updated author list and acknowledgements, fixed typos and other minor issues

Published
2023

83. Direct-Laser-Written Polymer Nanowire Waveguides for Broadband Single Photon Collection from Epitaxial Quantum Dots into a Gaussian-like Mode

Author

Perez, Edgar, Haws, Cori, Davanco, Marcelo, Song, Jindong, Sapienza, Luca, and Srinivasan, Kartik

Subjects
Physics - Optics, Condensed Matter - Mesoscale and Nanoscale Physics, Physics - Applied Physics, Quantum Physics
Abstract

Single epitaxial quantum dots (QDs) embedded in nanophotonic geometries are a leading technology for quantum light generation. However, efficiently coupling their emission into a single mode fiber or Gaussian beam often remains challenging. Here, we use direct laser writing (DLW) to address this challenge by fabricating 1 $\mu$m diameter polymer nanowires (PNWs) in-contact-with and perpendicular-to a QD-containing GaAs layer. QD emission is coupled to the PNW's HE$_{11}$ waveguide mode, enhancing collection efficiency into a single-mode fiber. PNW fabrication does not alter the QD device layer, making PNWs well-suited for augmenting preexisting in-plane geometries. We study standalone PNWs and PNWs in conjunction with metallic nanoring devices that have been previously established for increasing extraction of QD emission. We report methods that mitigate standing wave reflections and heat, caused by GaAs's absorption/reflection of the lithography beam, which otherwise prevent PNW fabrication. We observe a factor of $(3.0 \pm 0.7)\times$ improvement in a nanoring system with a PNW compared to the same system without a PNW, in line with numerical results, highlighting the PNW's ability to waveguide QD emission and increase collection efficiency simultaneously. These results demonstrate new DLW functionality in service of quantum emitter photonics that maintains compatibility with existing top-down fabrication approaches., Comment: Comments welcomed

Published
2023

84. Uncovering the Background-Induced bias in RGB based 6-DoF Object Pose Estimation

Author

Govi, Elena, Sapienza, Davide, Scribano, Carmelo, Poppi, Tobia, Franchini, Giorgia, Ardòn, Paola, Verucchi, Micaela, and Bertogna, Marko

Subjects
Computer Science - Computer Vision and Pattern Recognition, Computer Science - Artificial Intelligence, I.2.10, I.4.0
Abstract

In recent years, there has been a growing trend of using data-driven methods in industrial settings. These kinds of methods often process video images or parts, therefore the integrity of such images is crucial. Sometimes datasets, e.g. consisting of images, can be sophisticated for various reasons. It becomes critical to understand how the manipulation of video and images can impact the effectiveness of a machine learning method. Our case study aims precisely to analyze the Linemod dataset, considered the state of the art in 6D pose estimation context. That dataset presents images accompanied by ArUco markers; it is evident that such markers will not be available in real-world contexts. We analyze how the presence of the markers affects the pose estimation accuracy, and how this bias may be mitigated through data augmentation and other methods. Our work aims to show how the presence of these markers goes to modify, in the testing phase, the effectiveness of the deep learning method used. In particular, we will demonstrate, through the tool of saliency maps, how the focus of the neural network is captured in part by these ArUco markers. Finally, a new dataset, obtained by applying geometric tools to Linemod, will be proposed in order to demonstrate our hypothesis and uncovering the bias. Our results demonstrate the potential for bias in 6DOF pose estimation networks, and suggest methods for reducing this bias when training with markers., Comment: 17 pages, 10 figures, submitted to EURASIP Journal on Image and Video Processing

Published
2023

87. Data Sharing Governance in Digital Twins and Smart Cities: The European Data Strategy

Author

Sapienza, Salvatore, Palmirani, Monica, Greco, Sara, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Kö, Andrea, editor, Kotsis, Gabriele, editor, Tjoa, A Min, editor, and Khalil, Ismail, editor

Published
2024
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95. Ditan Acute tReatments: Effectiveness and Tolerability (DART) (DART)

Author

IRCCS National Neurological Institute "C. Mondino" Foundation, Società italiana per lo studio delle Cefalee (SISC), Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Università degli Studi dell'Aquila, University of Roma La Sapienza, Azienda Ospedaliero Universitaria Policlinico Modena, Ospedale di Piove di Sacco, Azienda Ospedaliero-Universitaria di Parma, Azienda Ospedaliera S. Maria della Misericordia, Azienda Ospedaliera Città della Salute e della Scienza di Torino, Cliniche Humanitas Gavazzeni, University of Campania "Luigi Vanvitelli", Ospedale di Prato, Azienda Policlinico Umberto I, Auxologico San Luca, Milano, ASST Spedali Civili, Brescia, Carlo Besta Neurological Institute, and Luigi Francesco Iannone, Researcher

Published
2023

96. Gepant treAtments: EffectIveNess and tolERability (GAINER) (GAINER)

Author

IRCCS National Neurological Institute "C. Mondino" Foundation, Società italiana per lo studio delle Cefalee (SISC), Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Università degli Studi dell'Aquila, University of Roma La Sapienza, Azienda Ospedaliero Universitaria Policlinico Modena, Ospedale di Piove di Sacco, Azienda Ospedaliero-Universitaria di Parma, Azienda Ospedaliera S. Maria della Misericordia, Azienda Ospedaliera Città della Salute e della Scienza di Torino, Cliniche Humanitas Gavazzeni, University of Campania "Luigi Vanvitelli", Ospedale di Prato, Azienda Policlinico Umberto I, Auxologico San Luca, Milano, ASST Spedali Civili, Brescia, Carlo Besta Neurological Institute, and Luigi Francesco Iannone, Researcher

Published
2023

98. Registry for Evaluation of Lumbar Arthrodesis Sagittal alignmEnt (RELAPSE)

Author

IRCCS National Neurological Institute "C. Mondino" Foundation, University of Roma La Sapienza, Istituto Clinico Humanitas, Niguarda Hospital, Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Istituto Clinico Città Studi, Milan, ASST Gaetano Pini-CTO, ASST Fatebenefratelli Sacco, Città di Pavia Clinic, Pavia, Fondazione IRCCS Policlinico San Matteo di Pavia, Azienda Ospedaliera, Ospedale Civile di Legnano, A.O. Ospedale Papa Giovanni XXIII, University of Siena, IRCSS Humanitas Research Hospital, Rozzano, Milan, University of Pavia, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Orthopedic Specialty Institute, Carlo Besta Neurological Institute, and Fabio Cofano, MD, MD, PhD, Researcher

Published
2023

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