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Despite these interventions, there is no detection of serovar new serovar of dengue and dengue-like illness (Kathmandu Syndrome?) is on the rise in Kathmandu. Dengue is a febrile disease caused by the dengue virus (Flaviviridae Family) transmitted by I Aedes i mosquitoes ( I Aedes aegypti i and I Aedes albopictus i ). [Extracted from the article]

The World Health Organization (WHO) issued an alert about the Camel virus [Middle East Respiratory Syndrome (MERS)]. Middle East respiratory syndrome coronavirus (MERS-CoV) - Qatar, 12 May 2022. https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON370 (24 November 2022, date last accessed). [Extracted from the article]

A clupeid group (Hilsa) in the Indian sub-continent is represented by three species viz., Tenualosa toli, T. ilisha and Hilsa kelee, which has great economic significance for the fishers. Tenualosa toil is observed to have narrow distribution in the Indian sub-continent, along with vulnerability status. The present study describes the morphological and meristic features of T. toli collected from the Narmada estuary, Gujarat, India. A single specimen was collected from the bag net catches (10 mm cod-end mesh size) - from Bhadbhut fishing site in December 2019. The size of specimen with a total length of 298 mm, standard length of 224 mm, and weight of 214 g. The morphometric and meristic characters were assessed and compared with other published literature. The present investigation of T. toli suggested that immediate measures should be adopted to rejuvenate the species in the aquatic habitats. [ABSTRACT FROM AUTHOR]

Shiyan Yang,1,* Weibo Jiang,1,* Xiao Ma,2,* Zuobin Wang,3 Robert L Sah,4,5 Jincheng Wang,1 Yang Sun1 1Orthopedic Medical Center, the Second Hospital of Jilin University, Changchun, Jilin, 130000, People’s Republic of China; 2Department of Orthopedics, the China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130000, People’s Republic of China; 3International Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology, Changchun, Jilin, 130000, People’s Republic of China; 4Department of Bioengineering, University of California–San Diego, La Jolla, CA, 92037, USA; 5Center for Musculoskeletal Research, Institute of Engineering in Medicine, University of California–San Diego, La Jolla, CA, 92037, USA*These authors contributed equally to this workCorrespondence: Yang Sun, Orthopedic Medical Center, the Second Hospital of Jilin University, Changchun, 130000, Jilin, People’s Republic of China, Tel/Fax +86 18744000871, Email sunyang@jlu.edu.cnAbstract: Three-dimensional (3D) printing is serving as the most promising approach to fabricate personalized titanium (Ti) implants for the precise treatment of complex bone defects. However, the bio-inert nature of Ti material limits its capability for rapid osseointegration and thus influences the implant lifetime in vivo. Despite the macroscale porosity for promoting osseointegration, 3D-printed Ti implant surface morphologies at the nanoscale have gained considerable attention for their potential to improve specific outcomes. To evaluate the influence of nanoscale surface morphologies on osseointegration outcomes of 3D-printed Ti implants and discuss the available strategies, we systematically searched evidence according to the PRISMA on PubMed, Embase, Web of Science, and Cochrane (until June 2022). The inclusion criteria were in vivo (animal) studies reporting the osseointegration outcomes of nanoscale morphologies on the surface of 3D-printed Ti implants. The risk of bias (RoB) was assessed using the Systematic Review Centre for Laboratory Animal Experimentation (SYRCLE’s) tool. The quality of the studies was evaluated using the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines. (PROSPERO: CRD42022334222). Out of 119 retrieved articles, 9 studies met the inclusion criteria. The evidence suggests that irregular nano-texture, nanodots and nanotubes with a diameter of 40– 105nm on the surface of porous/solid 3D-printed Ti implants result in better osseointegration and vertical bone ingrowth compared to the untreated/polished ones by significantly promoting cell adhesion, matrix mineralization, and osteogenic differentiation through increasing integrin expression. The RoB was low in 41.1% of items, unclear in 53.3%, and high in 5.6%. The quality of the studies achieved a mean score of 17.67. Our study demonstrates that nanostructures with specific controlled properties on the surface of 3D-printed Ti implants improve their osseointegration. However, given the small number of studies, the variability in experimental designs, and lack of reporting across studies, the results should be interpreted with caution.Keywords: nano-pattern, 3D-printed, titanium implant, surface modification, osseointegration