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This paper presents data on the ENEARc subsample of the larger ENEAR survey of nearby early-type galaxies. The ENEARc galaxies belong to clusters and were specifically chosen to be used for the construction of a Dn-� template. The ENEARc sample includes new measurements of spectroscopic and photometric parameters (redshift, velocity dispersion, line index Mg2, and the angular diameter dn), as well as data from the literature. New spectroscopic data are given for 229 cluster early-type galaxies, and new photometry is presented for 348 objects. Repeat and overlap observations with external data sets are used to construct a final merged catalog consisting of 640 early-type galaxies in 28 clusters. Objective criteria, based on catalogs of groups of galaxies derived from complete redshift surveys of the nearby universe, are used to assign galaxies to clusters. In a companion paper, these data are used to construct the template Dn-� distance relation for early-type galaxies, which has been used to estimate galaxy distances and derive peculiar velocities for the ENEAR all-sky sample.

In this paper R-band photometric and velocity dispersion measurements for a sample of 452 elliptical and S0 galaxies in 28 clusters are used to construct a template D_n-sigma relation. This template relation is constructed by combining the data from the 28 clusters, under the assumption that galaxies in different clusters have similar properties. The photometric and spectroscopic data used consist of new as well as published measurements, converted to a common system, as presented in a accompanying paper. The resulting direct relation, corrected for incompleteness bias, is log{D_n} =1.203 log{sigma} + 1.406; the zero-point has been defined by requiring distant clusters to be at rest relative to the CMB. This zero-point is consistent with the value obtained by using the distance to Virgo as determined by the Cepheid period-luminosity relation. This new D_n-sigma relation leads to a peculiar velocity of -72 (\pm 189) km/s for the Coma cluster. The scatter in the distance relation corresponds to a distance error of about 20%, comparable to the values obtained for the Fundamental Plane relation. Correlations between the scatter and residuals of the D_n-sigma relation with other parameters that characterize the cluster and/or the galaxy stellar population are also analyzed. The direct and inverse relations presented here have been used in recent studies of the peculiar velocity field mapped by the ENEAR all-sky sample.

An embedded silica optical microfiber knot resonator humidity sensor is presented. As silica has a poor response to environmental humidity changes, a surrounding layer of Nafion is used as a transducer. Spectral characterization and also a procedure to determine the coupling and total loss coefficients are presented. Sensitivity as high as (0.29±0.01) nm/% relative humidity has been noticed. Possible issues that emerge from the use of Nafion such as bulk swelling, refractive index hysteresis, as well as a saturation process, are discussed.

Production Optimization is one of the most complex and multi-disciplinary task in the oil & gas industry from an operational point of view. Optimization involves surface asset all along its production life and requires a continuous improvement process. Improvements, modifications, and temporary upsets in surface facilities during operation phase create the necessity to manage and optimize production scenarios with a more tight time-frame. Technology improvements have enabled a widespread use of integrated simulation models for a better asset management to be fully combined with measured field data. This paper shows a dedicated workflow for surface facilities – gathering system and process plant - production enhancement and management using an advanced optimization technique based on a biogenetic algorithm. The main feature of the proposed workflow is the ability to control many variables simultaneously according to the system constraints even with complex, conflicting, and non-direct interconnections and objectives to be reached. The workflow and the optimization approach are included in a wider integrated tool for production management, called rabbit™ - Risked Algorithm for Biogenetical Balance Integration Tool. Other features of this tool, such as transient phenomena and risk analysis evaluations, complete the ability of the tool to support the production and operation management. This paper will provide a useful description of how the tool can contribute in definition of field potential, production optimization and planning, minimizing production losses during planned/unplanned upsets as well as supporting debottlenecking activities. It will provide some case studies of rabbit™ implementations on different oil and gas fields, both on-shore and off-shore, showing benefits on using the integrated workflow.

Owing to organ shortage, livers from old donors are increasingly used for transplantation. The function and duration of such transplanted livers are apparently comparable to those from young donors, suggesting that, despite some morphological and structural age-related changes, no major functional changes do occur in liver with age. We tested this hypothesis by performing a comprehensive study on proteasomes, major cell organelles responsible for proteostasis, in liver biopsies from heart-beating donors. Oxidized and poly-ubiquitin conjugated proteins did not accumulate with age and the three major proteasome proteolytic activities were similar in livers from young and old donors. Analysis of proteasomes composition showed an age-related increased of β5i/α4 ratio, suggesting a shift toward proteasomes containing inducible subunits and a decreased content of PA28α subunit, mainly in the cytosol of hepatocytes. Thus our data suggest that, proteasomes activity is well preserved in livers from aged donors, concomitantly with subtle changes in proteasome subunit composition which might reflect the occurrence of a functional remodelling to maintain an efficient proteostasis. Gender differences are emerging and they deserve further investigations owing to the different aging trajectories between men and women. Finally, our data support the safe use of livers from old donors for transplantation. Owing to organ shortage, livers from old donors are increasingly used for transplantation. The function and duration of such transplanted livers are apparently comparable to those from young donors, suggesting that, despite some morphological and structural age-related changes, no major functional changes do occur in liver with age. We tested this hypothesis by performing a comprehensive study on proteasomes, major cell organelles responsible for proteostasis, in liver biopsies from heart-beating donors. Oxidized and poly-ubiquitin conjugated proteins did not accumulate with age and the three major proteasome proteolytic activities were similar in livers from young and old donors. Analysis of proteasomes composition showed an age-related increased of β5i/α4 ratio, suggesting a shift toward proteasomes containing inducible subunits and a decreased content of PA28α subunit, mainly in the cytosol of hepatocytes. Thus our data suggest that, proteasomes activity is well preserved in livers from aged donors, concomitantly with subtle changes in proteasome subunit composition which might reflect the occurrence of a functional remodelling to maintain an efficient proteostasis. Gender differences are emerging and they deserve further investigations owing to the different aging trajectories between men and women. Finally, our data support the safe use of livers from old donors for transplantation.

We present results from a study of the photometric redshift performance of the Dark Energy Survey (DES), using the early data from a Science Verification (SV) period of observations in late 2012 and early 2013 that provided science-quality images for almost 200 sq.~deg.~at the nominal depth of the survey. We assess the photometric redshift performance using about 15000 galaxies with spectroscopic redshifts available from other surveys. These galaxies are used, in different configurations, as a calibration sample, and photo-$z$'s are obtained and studied using most of the existing photo-$z$ codes. A weighting method in a multi-dimensional color-magnitude space is applied to the spectroscopic sample in order to evaluate the photo-$z$ performance with sets that mimic the full DES photometric sample, which is on average significantly deeper than the calibration sample due to the limited depth of spectroscopic surveys. Empirical photo-$z$ methods using, for instance, Artificial Neural Networks or Random Forests, yield the best performance in the tests, achieving core photo-$z$ resolutions $\sigma_{68} \sim 0.08$. Moreover, the results from most of the codes, including template fitting methods, comfortably meet the DES requirements on photo-$z$ performance, therefore, providing an excellent precedent for future DES data sets., Comment: Published in MNRAS. This version accounts for minor comments in the journal review

We present the combination of optical data from the Science Verification phase of the Dark Energy Survey (DES) with near infrared data from the ESO VISTA Hemisphere Survey (VHS). The deep optical detections from DES are used to extract fluxes and associated errors from the shallower VHS data. Joint 7-band ($grizYJK$) photometric catalogues are produced in a single 3 sq-deg DECam field centred at 02h26m$-$04d36m where the availability of ancillary multi-wavelength photometry and spectroscopy allows us to test the data quality. Dual photometry increases the number of DES galaxies with measured VHS fluxes by a factor of $\sim$4.5 relative to a simple catalogue level matching and results in a $\sim$1.5 mag increase in the 80\% completeness limit of the NIR data. Almost 70\% of DES sources have useful NIR flux measurements in this initial catalogue. Photometric redshifts are estimated for a subset of galaxies with spectroscopic redshifts and initial results, although currently limited by small number statistics, indicate that the VHS data can help reduce the photometric redshift scatter at both $z1$. We present example DES+VHS colour selection criteria for high redshift Luminous Red Galaxies (LRGs) at $z\sim0.7$ as well as luminous quasars. Using spectroscopic observations in this field we show that the additional VHS fluxes enable a cleaner selection of both populations with $, Comment: 18 pages, 11 figures, Accepted for publication in MNRAS

Background The reliability of endoscopic findings after adult intestinal transplantation on short-term follow-up has been shown. The aim of this study was to evaluate in a long-term follow-up the diagnostic value of endoscopies compared with the biopsy value. Methods We evaluated 52 endoscopies over a period of 2 years (2 in each patient in 2010 and 1 in each patient in 2011, plus 1 endoscopy for suspected post-transplant lymphoproliferative disease [PTLD]) on 17 recipients transplanted between the years 2000 and 2006 (more than 5 years of follow-up). Results All the 52 endoscopic findings were comparable to biopsy definitive results: only 1 case of mild enteritis and 1 case of Epstein-Barr virus (EBV) chronic infection at biopsy were not diagnosed by endoscopy. One case of rectal PTLD and 1 of EBV-related enteritis were diagnosed by use of both procedures. Specificity was 98%: we did not calculate sensitivity because no episodes of rejection were diagnosed because recipients were stable in long-term follow-up. Conclusions Endoscopy is a reliable procedure even on a long-term follow-up after intestinal transplantation, allowing a support to biopsy for diagnosis on adult recipients, especially for EBV infections and PTLD surveillance.

We present a comparison between the peculiar velocity field measured from the ENEAR all-sky $D_n-\sigma$ catalog and that derived from the galaxy distribution of the IRAS PSCz redshift survey. The analysis is based on a modal expansion of these data in redshift space by means of spherical harmonics and Bessel functions. The effective smoothing scale of the expansion is almost linear with redshift reaching 1500km/s at 3000km/s. The general flow patterns in the filtered ENEAR and PSCz velocity fields agree well within 6000km/s, assuming a linear biasing relation between the mass and the PSCz galaxies. The comparison allows us to determine the parameter $\beta=\Omega^{0.6}/b$, where $\Omega$ is the cosmological density parameter and $b$ is the linear biasing factor. A likelihood analysis of the ENEAR and PSCz modes yields $\beta=0.5 +- 0.1$, in good agreement with values obtained from Tully-Fisher surveys., Comment: Submitted to MNRAS

We use the recently completed redshift-distance survey of nearby early-type galaxies (ENEAR) to measure the dipole component of the peculiar velocity field to a depth of cz ~ 6000 km/s. The sample consists of 1145 galaxies brighter than m_B=14.5 and cz < 7000 km/s, uniformly distributed over the whole sky, and 129 fainter cluster galaxies within the same volume. Most of the Dn-sigma distances were obtained from new spectroscopic and photometric observations conducted by this project, ensuring the homogeneity of the data over the whole sky. These 1274 galaxies are objectively assigned to 696 objects -- 282 groups/clusters and 414 isolated galaxies. We find that within a volume of radius ~ 6000 km/s, the best-fitting bulk flow has an amplitude of |vbulk| =220 +/- 42 km/s in the CMB restframe, pointing towards l=304 +/- 16 degrees, b=25 +/- 11 degrees. The error in the amplitude includes statistical, sampling and possible systematic errors. This solution is in excellent agreement with that obtained by the SFI Tully-Fisher survey. Our results suggest that most of the motion of the Local Group is due to fluctuations within 6000 km/s, in contrast to recent claims of large amplitude bulk motions on larger scales., 11 pages, 2 figures, ApJL, accepted (updated results; matches accepted version)

We introduce two new pair statistics, which relate close galaxy pairs to the merger and accretion rates. We demonstrate the importance of correcting these (and other) pair statistics for selection effects related to sample depth and completeness. In particular, we highlight the severe bias that can result from the use of a flux-limited survey. The first statistic, denoted N_c, gives the number of companions per galaxy, within a specified range in absolute magnitude. N_c is directly related to the galaxy merger rate. The second statistic, called L_c, gives the total luminosity in companions, per galaxy. This quantity can be used to investigate the mass accretion rate. Both N_c and L_c are related to the galaxy correlation function and luminosity function in a straightforward manner. We outline techniques which account for various selection effects, and demonstrate the success of this approach using Monte Carlo simulations. If one assumes that clustering is independent of luminosity (which is appropriate for reasonable ranges in luminosity), then these statistics may be applied to flux-limited surveys. These techniques are applied to a sample of 5426 galaxies in the SSRS2 redshift survey. Using close dynamical pairs, we find N_c(-21

The decarbonylation reaction of methyl formate induced by Mg(OMe) 2 , in the presence of benzyl chloride and dichlorobis(triphenylphosphine)palladium gives rise selectively to methyl phenylethanoate with turnover numbers and turnover frequencies up to ca. 2400 and 1000 h −1 , respectively.

We investigate the dependence of the local galaxy luminosity function on morphology using 5,404 galaxies from the recently enlarged Second Southern Sky Redshift Survey (SSRS2). Over the range -22 \le M_B \le -14 ($H_0 = 100 km/s/Mpc), the luminosity function of early-type galaxies is well fitted by a Schechter function with parameters M_*=-19.37^{+0.10}_{-0.11}, alpha=-1.00^{+0.09}_{-0.09} and phi_*=0.0044 +/- 0.0008 Mpc^{-3}. The spiral luminosity function is very similar and is well fitted by the parameters M_*=-19.43^{+0.08}_{-0.08}, alpha=-1.11^{+0.07}_{-0.06} and phi_*=0.0080 +/- 0.0014 Mpc^{-3} over the same range in absolute magnitude. The flat faint end of the early-type luminosity function is consistent with earlier measurements from the CfA Redshift Survey (Marzke et al. 1994) but is significantly steeper than the slope measured in the Stromlo-APM survey (Loveday et al. 1992). Combined with the increased normalization of the overall LF measured from intermediate redshift surveys, the flat faint-end slope of the E/S0 LF produces no-evolution models which reproduce the deep HST counts of early-type galaxies remarkably well. However, the observed normalization of the SSRS2 LF is consistent with the low value measured in other local redshift surveys. The cause of this low-redshift anomaly remains unknown. The luminosity function of irregular and peculiar galaxies in the SSRS2 is very steep: M_*=-19.78^{+0.40}_{-0.50}, alpha=-1.81^{+0.24}_{-0.24} and phi_*=0.0002 +/- 0.00008 Mpc^{-3}. The steep slope is consistent with the LFs measured for Sm-Im galaxies in the CfA survey, UV-selected galaxies (Treyer et al. 1997), star-forming field galaxies (Bromley et al. 1997) and the bluest galaxies in the SSRS2 (Marzke & da Costa 1997)., Comment: 35 pages + 9 figures + 4 tables. Latex 2.09 with AASTex v. 4.0, to appear in the Astrophysical Journal

We report redshifts, magnitudes and morphological classifications for 5369 galaxies with $m_B \leq 15.5$ and 57 galaxies fainter than this limit, in two regions covering a total of 1.70 steradians in the southern celestial hemisphere. The galaxy catalog is drawn primarily from the list of non-stellar objects identified in the Guide Star Catalog (Lasker et al. 1990, AJ 99, 2019; hereafter GSC). The galaxies have positions accurate to about 1 arc sec and magnitudes with an rms scatter of about 0.3 mag. We compute magnitudes ($m_{SSRS2}$) from the relation between instrumental GSC magnitudes and the photometry by Lauberts & Valentijn (1989). From a comparison with CCD photometry, we find that our system is homogeneous across the sky and corresponds to magnitudes measured at the isophotal level $\sim$ 26 mag arcsec$^{-2}$. The precision of the radial velocities is of \sim 40 km/s and the redshift survey is more than 99% complete to the $m_{SSRS2}$ = 15.5 magnitude limit. This sample is in the direction opposite to the CfA2; in combination the two surveys provide an important database for studies of the properties of galaxies and their large-scale distribution in the nearby Universe., 20 pages, uses AASTeX 4.0 macros. Includes 3 tables and 4 Postscripts figures. Scheduled for publication in the AJ 1998 July issue

In order to compare the standard swim-up semen preparation with and without test yolk buffer (TYB) incubation in intrauterine insemination (IUI), we conducted a prospective multicentre randomized trial. A total of 121 infertile couples with male factor (n = 52) or unexplained infertility (n = 69) was randomly assigned to two groups following ovulation induction. Semen was prepared by standard swim-up in group A (n = 64) and by swim-up followed by TYB incubation in group B (n = 57). A maximum of two IUI cycles was performed. A total of 104 cycles was performed in the swim-up group and 90 in the TYB group. Overall, 15 pregnancies were achieved in group A and 23 in group B, with an overall pregnancy rate of 24.8 and 50.0% per patient respectively (chi2(1), P < 0.05). In the male factor group, pregnancy was achieved in six out of 24 couples (25%) following standard swim-up and in six out of 28 (21.4%) following swim-up and TYB incubation (chi2(1), not significant). In the unexplained infertility group, pregnancy was recorded in nine out of 40 couples (22.5%) following standard swim-up and in 17 out of 29 couples (58.6%) following swim-up and TYB incubation (chi2(1), P < 0.05).

We use the two-point correlation function to calculate the clustering properties of the recently completed SSRS2 survey. The redshift space correlation function for the magnitude-limited SSRS2 is given by xi(s)=(s/5.85 h-1 Mpc)^{-1.60} for separations between 2 < s < 11 h-1 Mpc, while our best estimate for the real space correlation function is xi(r) = (r/5.36 h-1 Mpc)^{-1.86}. Both are comparable to previous measurements using surveys of optical galaxies over much larger and independent volumes. By comparing the correlation function calculated in redshift and real space we find that the redshift distortion on intermediate scales is small. This result implies that the observed redshift-space distribution of galaxies is close to that in real space, and that beta = Omega^{0.6}/b < 1, where Omega is the cosmological density parameter and b is the linear biasing factor for optical galaxies. We also use the SSRS2 to study the dependence of xi on the internal properties of galaxies. We confirm earlier results that luminous galaxies (L>L*) are more clustered than sub-L* galaxies and that the luminosity segregation is scale-independent. We find that early types are more clustered than late types, but that in the absence of rich clusters, the relative bias between early and late types in real space, is not as strong as previously estimated. Furthermore, both morphologies present a luminosity-dependent bias, with the early types showing a slightly stronger dependence on luminosity. We also find that red galaxies are significantly more clustered than blue ones, with a mean relative bias stronger than that seen for morphology. Finally, we find that the relative bias between optical and iras galaxies in real space is b_o/b_I $\sim$ 1.4., 43 pages, uses AASTeX 4.0 macros. Includes 8 tables and 16 Postscript figures, updated references

The incidence of early rejection after intestinal transplantation correlates with heightened risk of graft loss and mortality. Many different induction or pre-conditioning protocols have been reported in the last 10 yr to improve outcomes; however, sepsis remains prevalent and diminishes long-term results. We recently began a "2-dose" alemtuzumab trial protocol - 15 mg at day 0 and 15 mg repeated on day 7 - with the hope of reducing our infection rate. We compared three different protocols used at our institution (daclizumab, conventional "4-dose" alemtuzumab, and "2-dose" alemtuzumab). There was a significantly lower rate of early rejection with the "2-dose" alemtuzumab protocol in our study group of mainly (88%) intestinal grafts without accompanying liver engraftment with its protective immunologic effect. Sepsis remained low. Longer follow-up will be required to evaluate the effects of this new protocol on longer-term outcomes.

Background Chronic intestinal pseudo-obstruction (CIPO) has been treated in adults by total parenteral nutrition (TPN) or, if complications arise, by multivisceral transplantation because the stomach is often involved. Eleven adults with CIPO were transplanted by intestinal graft in our center from 2000 to 2011. Methods Nine patients underwent isolated intestinal transplant and 2 patients had multivisceral transplant. Immunosuppression was represented by FK and steroids plus induction with alemtuzumab, daclizumab, or thymoglobulin. Average age at transplant was 33.5 years. We reported 1 graftectomy, followed by retransplantation. Results Seven patients are currently alive with working small bowel; cause of death was infection in the 4 remaining cases. In 9 isolated intestinal transplants, we performed different digestive reconstructions to allow gastric emptying. In 2 cases we were forced, after transplant, to perform ileostomy to improve intestinal motility. Graft and patient survival after 5 years are 60% and 70%, respectively, while after 10 years, 45% and 56%, respectively. Conclusions Adults with CIPO and irreversible TPN complications benefit from isolated intestinal transplant with different surgical techniques to empty the native stomach: this strategy achieves good gastric emptying, with effective establishment of oral feeding and graft and patient survivals comparable to isolated intestinal transplant for short bowel syndrome.

Steroid-resistant acute cellular rejection (ACR) and chronic rejection (CR) are still major concerns after intestinal transplantation. We report our experience from a single center on 48 adults recipients using 49 grafts from 2001 to 2011, immunosuppressing them initially with daclizumab initially and later Alemtuzumab. Overall patient survival was 41.9% at 10 years while graft survival was 38.5%. The steroid-resistant ACR population of 14 recipients (28.5%) experienced 50% mortality mainly due to sepsis, while the five (8%) CR recipients, included two survivors. All but 1 graft was placed without a liver. CR was often preceded by ACR episodes. Mortality related to steroid-resistant ACR and CR still affects the intestinal transplant population despite induction/preconditioning, especially in the absence of a protective liver effect of the liver. New immunosuppressive strategies are needed.

The oxidation behaviour of gentisic acid, from which a humic acid model was synthesized, was studied. Electrochemical investigation coupled with Electron Spin Resonance analysis revealed the complexity of the mechanism. Coupled chemical reactions appeared after the two electron oxidation, leading to trihydroxybenzoic acids, and to dimeric compounds. The presence of methylenic groups, particularly important to mimic the flexibility and aggregative properties of natural humic substance, was confirmed. Assuming a free radical mechanism for the chemical evolution of humic substances, metal ions could help the reaction process, leading to efficient spin-trapping matters to be considered in water treatments.

Time-resolved photoluminescence decay measurements have been performed on samples with varying-sized self-assembled InAs/GaAs quantum dot ensembles, formed by substrate misorientation. Ground-state radiative recombination lifetimes from 0.8 to 5.3 ns in the incident power density range of 0.05–3400 W cm−2 at a temperature of 77 K have been obtained. It was found that a reduction of the quantum dot size led to a corresponding reduction of the radiative lifetime. The evident biexponential decay was obtained for the ground state emission of the quantum dot array, with the slower second component attributed to a carrier recapturing process.

Background Combined liver-kidney transplantation (LKT) is considered to be a safe procedure, but the appropriate immunosuppressive regimen is unclear. Patients and methods Between January 1997 and October 2011, 55 patients were listed for LKT: 45 (82%) were effectively transplanted, 5 (9.2%) died whereon here the waiting list, 3 (5.5%) temporarily out of waiting list, 1 (1.8%) was on waiting list and 1 (1.8%) refused LKT. Five LKTs treated with cyclosporine (CyA) were excluded from the analysis. Mean recipient age was 50.32 ± 10.32 years (14–65), MELD score at time of LKT was 19.22 ± 4.69 (8–29), mean waiting list time was 8.14 ± 9.50 months (0.1–35.76), and follow-up, 4.09 ± 3.02 years (0.01–10.41). Main indications for LKT were policystic disease (n = 15; 37%), hepatitis virus C (HCV)-related cirrhosis (n = 9; 22%) metabolic disease (n = 5; 13%), hepatitis virus B (HBV) cirrhosis (n = 4; 10%), alcoholic cirrhosis (n = 4; 10%), and cholestatic disease (n = 3; 8%). Immunosuppressive regimen was based on tacrolimus and steroids in 40 cases with induction therapy with alemtuzumab (Campath; 0.3 mg/kg) in 13 of 40 instances cases administered on day 0 and day 7. Results Postoperative mortality was 2.5%. Acute cellular rejection episodes were biopsy-proven in 2 (5%) cases, post-LKT infections developed in 17 cases (42.5%), and de novo cancer developed in 3 (7.5%) cases. Similar 5-year overall survivals were obtained irrespective of the LKT indication: 100% in cholestatic and alcoholic cirrhosis patients, 86% in policystic disease, 75% in metabolic disease and HBV patients, and 66% in HCV cirrhosis. Overall survivals for the alemtuzumab vs without-induction therapy groups at 1, 3, and 5-years were 100%, 85.7%, and 85.7% vs 76%, 76%, and 70%, respectively ( P = .04). Conclusion An immunosuppressive regimen based on tacrolimus and steroids with induction therapy with alemtuzumab was safe, with excellent long-term results for combined LKT.

In some recent hypotheses, the ovary has been indicated as a source of insulin-like growth factor (IGF)-I, with synthesis regulated from local steroidal and non-steroidal substances. We measured IGF-I concentrations in both serum and follicular fluid of women undergoing in-vitro fertilization (IVF) and embryo transfer, in both induced and spontaneous cycles. It was found that serum and follicular IGF-I concentrations were correlated with follicular morphology, oocyte maturity, steroid concentrations and clinical characteristics of IVF cycles. In addition, we measured IGF-I concentrations in both peripheral and ovarian circulation to gain further detailed information on the contribution of the ovary to IGF-I production. The results of our study support the hypothesis that follicular IGF-I is probably derived by diffusion from peripheral circulation and that local production appears unlikely.

The relationship between neo-adjuvant chemotherapy prior to hepatectomy in patients with resectable colorectal liver metastases and post-operative morbidity still has to be clarified. Data from 242 patients undergoing hepatectomy for colorectal liver metastases, judged resectable at first observation, were reviewed and their clinical outcome was related to neo-adjuvant chemotherapy (125 patients). Selection biases were outlined and properly handled by means of propensity score analysis. Post-operative death was 1.2% and morbidity 40.9%. Pre-operative chemotherapy was only apparently related to higher morbidity (P = 0.021): multivariate analysis identified extension of hepatectomy and intra-operative blood loss as independent prognostic variables (P

The reconstruction of the peculiar velocity field from the 1.936~Jy iras selected sample of galaxies is compared to a similar reconstruction from an optically selected sample. A general method for combining different samples to reconstruct a self-consistent density and peculiar velocity field is presented. The method is applied to determine how sensitive the derived peculiar velocity field is to the characteristics of the sample used. The possibility that the iras galaxies do not trace the general galaxy population is explored adopting a simple model of linear biasing between the iras and optical samples. We find that the velocity fields derived from the two samples are consistent, within the estimated shot noise error, for the case of no relative bias. This result suggests that the predicted peculiar velocity field based on iras samples is not sensitive to the sampling properties of iras galaxies. Combined with previous suggestion of a relative biasing of iras galaxies on small scales (about 5 h^-1Mpc), this result suggests scale dependent biasing., Comment: tar-compressed and uudecoded postscript files, 12 pages+8 figures

This paper provides a key element for the calculation of the damage costs of air pollution, namely the valuation of mortality, important because premature mortality makes by far the largest contribution. Whereas several studies have tried to quantify the cost of air pollution mortality by multiplying a number of deaths by the ‘value of prevented fatality’ (also known as ‘value of statistical life’), we explain why such an approach is not correct and why one needs to evaluate the change in life expectancy due to air pollution. Therefore, an estimate for the monetary value of a life year (VOLY) is needed. The most appropriate method for determining VOLY is contingent valuation (CV). To determine VOLY for the EU, we have conducted a CV survey in 9 European countries: France, Spain, UK, Denmark, Germany, Switzerland, Czech Republic, Hungary, and Poland with a total sample size of 1463 persons. Based on the results from this 9-country CV survey we recommend a VOLY estimate of 40,000 € for cost–benefit analysis of air pollution policies for the European Union. As for confidence intervals, we argue that VOLY is at least 25,000 € and at the most 100,000 €.

We examine the impact of using photometric redshifts for studying the evolution of both the global galaxy luminosity function (LF) and that for different galaxy types. To this end we compare LFs obtained using photometric redshifts from the CFHT Legacy Survey (CFHTLS) D1 field with those from the spectroscopic survey VIMOS VLT Deep Survey (VVDS) comprising ~4800 galaxies. We find that for z, 29 pages, 10 figures. Approved for publication in The Astronomical Journal

In questo capitolo verrà affrontata un'analisi dei dati provenienti dagli studi nazionali ed internazionali relativi alla variabilità climatica. Al fine di rendere la disamina sul clima attuale ed approfondita verranno presentati scenari climatici per il futuro a partire da modelli numerici GCM (General Circulation Model) che saranno poi seguiti da due scenari caratterizzati da due approcci modellisitici strettamente legati allo studio della variabilità climatica: lo statistical downscaling e il dynamical dowscaling.

Wide angle and deep surveys, regardless of their primary purpose, always sample a large number of stars in the Galaxy and in its satellite system. We here make a forecast of the expected stellar sample resulting from the Dark Energy Survey and the perspectives that it will open for studies of Galactic structure and resolved stellar populations in general. An estimated 1.2x10^8 stars will be sampled in DES grizY filters. This roughly corresponds to 20% of all DES sources. Most of these stars belong to the stellar thick disk and halo of the Galaxy. DES will probe low-mass stellar and sub-stellar objects at depths from 3 to 8 times larger than SDSS. The faint end of the main-sequence will be densely sampled beyond 10 kpc. The slope of the low mass end of the stellar IMF will be constrained to within a few hundredth dex, even in the thick disk and halo. In the sub-stellar mass regime, the IMF slope will be potentially constrained to within dlog \phi(m) / dlog m ~ 0.1$. About 3x10^4 brown dwarf and at least 7.6x10^5 white dwarf candidates will be selected, the latter embedded into the thick disk and halo. The stellar halo flattening will also be constrained to within a few percent. DES will probe the main sequence of new Milky Way satellites and halo clusters for distances out to ~ 120 kpc, therefore yielding stellar surface density contrasts 1.6-1.7 times larger than those attainable with SDSS. It will also allow detection of these objects in the far reaches of the stellar halo, substantially increasing the number and quality of probes to the Galactic potential. Combined with northern samples, such as the SDSS, the DES stellar sample will yield constraints on the structure and stellar populations of Galactic components in unprecedented detail. In particular, the combined sample from both hemispheres will allow detailed studies of halo and thick disk asymmetries and triaxiality., Comment: 29 pages, 10 figures. Approved for publication in the Astronomical Journal

The adoption of precision agriculture in viticulture requires the knowledge of the spatial and temporal variability of available soil water. A three-years trial was carried out in Chianti (central Italy) on Sangiovese vine to test the prediction capacity of selected hydropedological models for two soil series cultivated with grape and for delineating hydrological functional units within two vineyards. The soils of the vineyards differentiated in structure, porosity and related hydropedological characteristics, as well as in salinity. Soils were mapped with a geophysical survey and six plots were selected in different morphological positions: summit, backslope and footslope. Water content, redox processes and temperature were monitored, and yield, phenological phases, and chemical analysis of grapes were determined. The isotopic ratio δ13C was measured in the wine ethanol upon harvesting to evaluate the degree of water stress suffered by vines. The grapes in each plot were collected for wine making in small barrels. The wines obtained were analysed and submitted to a blind organoleptic testing. The results demonstrated that the tested hydropedological models can be used for the prevision of the moisture status of soils cultivated with grape during summertime in Mediterranean climate. As foreseen by the models, the amount of mean daily transpirable soil water differed considerably between the vineyards and increased significantly along the three positions on slope in both vineyards and in every year, even during the very dry 2006. However, both the response of Sangiovese to water stress and the quality of wine were influenced by the interaction between transpirable water and salinity. The installation of IRIS tubes allowed confirmation of the occurrence of redox processes, although discoloration was influenced more by soil temperature, rather than by moisture. The map produced by once only geophysical survey mirrored only partially the seasonal hydropedology of these heavily tilled soils on slope.

We present theoretical models for the formation and evolution of populations of low-mass X-ray binaries (LMXB) in the two elliptical galaxies NGC 3379 and NGC 4278. The models are calculated with the recently updated StarTrack code (Belczynski et al., 2006), assuming only a primordial galactic field LMXB population. StarTrack is an advanced population synthesis code that has been tested and calibrated using detailed binary star calculations and incorporates all the important physical processes of binary evolution. The simulations are targeted to modeling and understanding the origin of the X-ray luminosity functions (XLF) of point sources in these galaxies. For the first time we explore the population XLF down to luminosities of 3X10^36 erg/s, as probed by the most recent observational results (Kim et al., 2006). We consider models for the formation and evolution of LMXBs in galactic fields with different CE efficiencies, stellar wind prescriptions, magnetic braking laws and initial mass functions. We identify models that produce an XLF in excellent agreement with the observations both in shape and absolute normalization. We also find that the treatment of the outburst luminosity of transient systems remains a crucial factor for the determination of the XLF since the modeled populations are dominated by transient X-ray systems., Comment: 54 pages, 22 figure, submitted to The Astrophysical Journal

We extend our published work on the neutral hydrogen content of early-type galaxies in the Virgo cluster using the catalogue of detected sources from the ALFALFA survey, by showing the 21cm spectra of all the detected galaxies and discussing a deeper analysis of the ALFALFA datacubes, searching for lower S/N sources. A view of the multiphase interstellar medium of M86 is also presented, by comparing images of the cold, warm and hot phases., To appear in the Proceedings of the Conference "The Evolution of Galaxies through the Neutral Hydrogen Window", R. Minchin & E. Momjian eds

Building maps of the explored environment during a rescue application is important in order to locate the information acquired through robot sensors. A lot of work has been done on mapping 2D large environments, while the creation of 3D maps is still limited to simple and small environments, due to the costs of 3D sensors and of high computational requirements. In this paper we analyze the problem of building multi-level planar maps. These maps are useful when mapping large indoor environments (e.g., a multi-floor building) and can be effectively created by integrating robustness and efficiency of state-of-the-art 2D SLAM techniques using 2D laser range finder data, with the use of a precise IMU sensor and effective visual odometry techniques based on stereo vision for measuring plane displacements. The main advantages of the proposed solution, with respect to other kinds of 3D maps, are the low-cost of the sensors mounted on the robots and the possibility of exploiting results from 2D SLAM for exploring very large environments. Preliminary experimental results show the effectiveness of the proposed approach.

New type of carrier distribution among quantum dots — a spatially separated bipolar‐charging state — has been studied experimentally and theoretically. Experimental methods such as pump‐probe spectroscopy of electrically pumped samples and time‐resolved photoluminescenee were used. Theoretical approach based on a detailed statistics of carrier distribution was developed and proposed for interpretation of the experimental results.

Objective To determine the occurrence of carpal tunnel syndrome (CTS) and ulnar neuropathy at the elbow (UNE) in a cohort of floor cleaners and to check differences between workers with and without CTS. Methods All female floor cleaners of three major hospitals in Tuscany (Italy) were contacted. Clinical and electrophysiological severity of CTS and UNE were evaluated with standardized scales and symptoms were assessed with the self-administered Boston Questionnaire (BQ); demographic and non-occupational factors and durations of current and previous occupations were recorded. Univariate analysis of risk factors was performed in workers with and without CTS. Logistic regression was used to evaluate the capacity of independent variables to predict CTS. Results Out of a total of 179 cleaners, 145 (81%)—mean age 39.6 years (20–64 years)—were enrolled in the study; 70 (48%) had CTS (diagnosis based on clinical and electrophysiological findings). BQ symptom and hand function scores were anomalous in 108 (74%) and 84 (58%) subjects, respectively. UNE was detected in 7/103 women. Univariate analysis showed that cleaners with CTS were older, had greater BMI and longer exposure to cleaning with previous employers than those without CTS. In the logistic regression, the only predictor of CTS was cleaning with previous employers (O.R. 12.1, 95% CI 3–49.9). Conclusions These results indicate a high occurrence of CTS in floor cleaners; UNE is less frequent than CTS, presumably due to repetitive movements that stress wrists more than elbows. The only predictive factor of CTS was cleaning as an occupation with previous employers. Therefore, the actual risk factor for CTS could not be cleaning per se, but how this job is performed.

The valuation of human costs is a necessity, but this task poses many problems of method. A team made of a philosopher, a psychologist and a physician has been working with economist researchers in order to look into the meaning that the preferences announced at the time of the inquiries on human costs by QALY methods could assume. These methods are often used to obtain a valuation of the impact of a health attack on people's quality of life. The methods--in the frame of the argument assumed by the economic theory on well-being--hypothesize that people's choices depend mainly on cognitive work. The qualitative interviews show that the psychological construction process for the announced preferences largely overlap this frame. In this paper the authors hastily tackle the factors which have an effect on the preferences. They conclude that the QALY methods don't seem to be able to assess the quality of life nori to valuate the damage that the quality of life could include.

We measure radial gradients of the Mg2 index in 15 E-E/S0 and 14 S0 galaxies. Our homogeneous data set covers a large range of internal stellar velocity dispersions (2.0, Comment: 11 pages, 2 figures, to appear in ApJLetters

Time-resolved photoluminescence decay measurements have been performed on samples with varying sized self-assembled InAs/GaAs quantum dot ensembles, formed by substrate mis-orientation alone, but otherwise under identical growth conditions. Ground-state radiative recombination lifetimes from 0.8 to 5.3 ns in the incident energy density range of 0.79 pJcm-2 - 40 nJcm-2 at a temperature of 77 K were obtained. It was found that a reduction of the quantum dot size led to a corresponding reduction of the radiative lifetime. The evident bi-exponential decay was obtained for the ground state emission of the quantum dot array, with the slower second component attributed to a carrier re-capturing and indirect radiative recombination processes. Also experimental evidence of the effect of the AlGaAs barrier in InAs QDs emitting in the wavelength range 1200-1300nm is presented. Time-resolved photoluminescence measurements have been performed on samples with different compositions of Al in the barrier. A full discussion of the lifetimes of these near infra-red emitting dots will be presented.

Measurements of the THz absorption and the time-resolved photoluminescence have been performed on the same GaAs quantum well sample. The strength of the absorption at the internal 1s-2p exciton transition frequency is used as a measure of the density of excitons in the sample. When the interband pump laser is resonant with the Is exciton frequency, induced absorption at the 1s-2p frequency is clearly seen. If the same density of carriers is created pumping in the continuum, no significant 1s-2p absorption is seen in a time window of 450 ps. Complementary time-resolved photoluminescence experiments, detecting the emission at the exciton energy under the same pump conditions, show the PL intensity in resonant and nonresonant cases to be similar. The counter-intuitive existence of luminescence at the exciton energy simultaneously with the absence of the 1s-2p absorption is consistent with the recent theoretical predictions of Kira et al., Phys. Rev. Lett. 81, 3263 (1998).

Hubble Space Telescope revealed a dicothomy in the central surface brightness profiles of early-type galaxies, that subsequently have been grouped into two families: core, boxy, anisotropic systems and cuspy ("power law"), disky, rotating ones. Here we investigate whether a dicothomy is present also in the X-ray properties of the two families. We consider both their total soft emission (Lsx,tot), that is a measure of the galactic hot gas content, and their nuclear hard emission (Lhx,nuc), mostly coming from Chandra observations, that is a measure of the nuclear activity. At any optical luminosity, the highest Lsx,tot values are reached by core galaxies; this is explained with their being central dominant galaxies of groups, subclusters or clusters, in many of the logLsx,tot(erg/s)>~41.5 cases. The highest Lhx,nuc values, similar to those of classical AGNs, in this sample are hosted only by core galaxies; at low luminosity AGN levels, Lhx,nuc is independent of the central stellar profile shape. The presence of optical nuclei (also found by HST) is unrelated with the level of Lhx,nuc, even though the highest Lhx,nuc are all associated with optical nuclei. The implications of these findings for the galaxy evolution and the accretion modalities at the present epoch are discussed., 11 pages, in press in MNRAS

This presentation will discuss the issues limiting key exchange rates in fibre-based quantum key distribution systems, paying particular attention to the bottleneck of single-photon detectors. The approach of using 850 nm wavelength quantum channels is discussed. (4 pages)

BACKGROUND: In human reproduction, embryo implantation is complex and poorly understood. At present, no single markers are used in routine treatment to assay biochemical functions of the human embryo. Soluble human leukocyte antigen-G (sHLA-G) could be considered a possible marker of embryo developmental potential. It is localized primarily on the extravillous trophoblast, making this antigen a potential mediator of immune interaction at the maternal-fetal interface during gestation. METHODS: Soluble-HLA-G levels were evaluated by an enzyme-linked immunosorbent assay (ELISA) employing monoclonal antibody MEM-G9. It was evaluated in 318 media of single embryo cultures. We correlated the presence of sHLA-G with embryo morphology and the pregnancy obtained in that treatment cycle. RESULTS: No correlation was found between embryo morphology and sHLA-G levels. Pregnancy was observed only when the medium of at least one transferred embryo contained sHLA-G. In 26 out of 66 patients, none of the obtained embryos showed any detectable sHLA-G molecules and no pregnancy occurred. CONCLUSIONS: From our results, we propose sHLA-G as a potential marker of embryo development: the sHLA-G ELISA can be a useful biochemical assay in addition to embryo morphology in embryo selection for transfer in IVF treatment if there are other embryos with the same morphology.

Alterations of p53 are one of the most common molecular changes found in all types of lung tumors, suggesting a crucial role for p53 in bronchial carcinogenesis. However, the prognostic significance of p53 abnormalities in lung cancer patients is still unclear. By using genetic and immunohistochemical methods we have found p53 alterations in 40 of 53 (75%) primary, resected non-small cell lung cancer. A strong association (P = 0.0015) was found between deletions on chromosome region 17p13.3 and p53 mutations suggesting that loss of the wild-type p53 allele might be necessary for tumorigenesis. Correlations to clinicopathological parameters showed that p53 alterations (structural aberration of the gene and/or nuclear accumulation of the protein) are significantly linked with metastatic involvement of hilar and mediastinal lymph nodes (P < 0.01). Since the latter are well established prognostic factors for non-small cell lung cancer, p53 aberrations may also be a predictor of tumor aggressiveness.

We present central velocity dispersions and Mg$_2$ line indices for an all-sky sample of $\sim$ 1178 elliptical and S0 galaxies, of which 984 had no previous measures. This sample contains the largest set of homogeneous spectroscopic data for a uniform sample of elliptical galaxies in the nearby universe. These galaxies were observed as part of the ENEAR project, designed to study the peculiar motions and internal properties of the local early-type galaxies. Using 523 repeated observations of 317 galaxies obtained during different runs, the data are brought to a common zero-point. These multiple observations, taken during the many runs and different instrumental setups employed for this project, are used to derive statistical corrections to the data and are found to be relatively small, typically $\lsim$ 5% of the velocity dispersion and 0.01 mag in the \mg line-strength. Typical errors are about 8% in velocity dispersion and 0.01 mag in \mg, in good agreement with values published elsewhere., 179 pages, 8 figures, 5 tables. Full tables 4 and 5 start on page 41