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1,822 results on '"Rossell, Susan"'

54. Item-specific overlap between hallucinatory experiences and cognition in the general population: A three-step multivariate analysis of international multi-site data

Author

Chinchani, Abhijit M., Menon, Mahesh, Roes, Meighen, Hwang, Heungsun, Allen, Paul, Bell, Vaughan, Bless, Josef, Bortolon, Catherine, Cella, Matteo, Fernyhough, Charles, Garrison, Jane, Kozáková, Eva, Larøi, Frank, Moffatt, Jamie, Say, Nicolas, Suzuki, Mimi, Toh, Wei Lin, Zaytseva, Yuliya, Rossell, Susan L., Moseley, Peter, and Woodward, Todd S.

Published
2021
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71. Time of Day Differences in Neural Reward Functioning in Healthy Young Men

Author

Byrne, Jamie EM, Hughes, Matthew E, Rossell, Susan L, Johnson, Sheri L, and Murray, Greg

Subjects
Neurosciences, Clinical Research, 1.1 Normal biological development and functioning, 1.2 Psychological and socioeconomic processes, Underpinning research, Mental health, Brain, Brain Mapping, Brain Waves, Choice Behavior, Circadian Rhythm, Humans, Male, Nerve Net, Reference Values, Reward, Time Factors, circadian, diurnal, putamen, reward, sleep, striatum, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery
Abstract

Reward function appears to be modulated by the circadian system, but little is known about the neural basis of this interaction. Previous research suggests that the neural reward response may be different in the afternoon; however, the direction of this effect is contentious. Reward response may follow the diurnal rhythm in self-reported positive affect, peaking in the early afternoon. An alternative is that daily reward response represents a type of prediction error, with neural reward activation relatively high at times of day when rewards are unexpected (i.e., early and late in the day). The present study measured neural reward activation in the context of a validated reward task at 10.00 h, 14.00 h, and 19.00 h in healthy human males. A region of interest BOLD fMRI protocol was used to investigate the diurnal waveform of activation in reward-related brain regions. Multilevel modeling found, as expected, a highly significant quadratic time-of-day effect focusing on the left putamen (p < 0.001). Consistent with the "prediction error" hypothesis, activation was significantly higher at 10.00 h and 19.00 h compared with 14.00 h. It is provisionally concluded that the putamen may be particularly important in endogenous priming of reward motivation at different times of day, with the pattern of activation consistent with circadian-modulated reward expectancies in neural pathways (i.e., greater activation to reward stimuli at unexpected times of day). This study encourages further research into circadian modulation of reward and underscores the methodological importance of accounting for time of day in fMRI protocols.SIGNIFICANCE STATEMENT This is one of the first studies to use a repeated-measures imaging procedure to explore the diurnal rhythm of reward activation. Although self-reported reward (most often operationalized as positive affect) peaks in the afternoon, the present findings indicate that neural activation is lowest at this time. We conclude that the diurnal neural activation pattern may reflect a prediction error of the brain, where rewards at unexpected times (10.00 h and 19.00 h) elicit higher activation in reward brain regions than at expected (14.00 h) times. These data also have methodological significance, suggesting that there may be a time of day influence, which should be accounted for in neural reward studies.

Published
2017

78. Exploring Cognitive Functioning among Forensic Mental Health Inpatients.

Author

Cronje, Han-Mari, Nixon, Margaret, and Rossell, Susan L.

Abstract

A large proportion of forensic mental health (FMH) inpatients experience cognitive impairments, which may impact the extent to which they benefit from interventions aimed at reducing their risk of recidivism. These impairments should be identified and responded to as quickly and accurately as possible. The current study explored when and how FMH inpatients' cognition is assessed during their stay at a forensic hospital, with a cognitive profile being constructed of the sample. The medical files of inpatients who resided at the hospital in Melbourne (Australia) during January 2016 and December 2019 were reviewed retrospectively. A total of 99 medical files were identified. The type, timing and results of each cognitive assessment were collected. Frequency analysis revealed more than half of the sample received a cognitive assessment, with most of the cognitive assessments being conducted within the first year of an inpatient's admission to hospital. Between 19% and 31% of inpatients with available cognitive data demonstrated a global cognitive impairment, depending on the cognitive measure being used. These results highlight the value of assessing FMH inpatients for cognitive impairments to respond to them appropriately to increase their chances of rehabilitation. Careful consideration should be given to the type of cognitive assessment tool used among this demographic. [ABSTRACT FROM AUTHOR]

Published
2024
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98. Deep Brain Stimulation for Obsessive-Compulsive Disorder: Optimal stimulation sites

Author

Meyer, Garance M., primary, Hollunder, Barbara, additional, Li, Ningfei, additional, Butenko, Konstantin, additional, Dembek, Till A., additional, Hart, Lauren, additional, Nombela, Cristina, additional, Mosley, Philip, additional, Akram, Harith, additional, Acevedo, Nicola, additional, Borron, Benjamin M., additional, Chou, Tina, additional, Castaño Montoya, Juan Pablo, additional, Strange, Bryan, additional, Barcia, Juan A., additional, Tyagi, Himanshu, additional, Castle, David J., additional, Smith, Andrew H., additional, Choi, Ki Sueng, additional, Kopell, Brian H., additional, Mayberg, Helen S., additional, Sheth, Sameer A., additional, Goodman, Wayne, additional, Leentjens, Albert F.G., additional, Richardson, R. Mark, additional, Rossell, Susan L., additional, Bosanac, Peter, additional, Cosgrove, G. Rees, additional, Kuhn, Jens, additional, Visser-Vandewalle, Veerle, additional, Figee, Martijn, additional, Dougherty, Darin D., additional, Siddiqi, Shan H., additional, Zrinzo, Ludvic, additional, Joyce, Eileen, additional, Baldermann, Juan Carlos, additional, Fox, Michael D., additional, Neudorfer, Clemens, additional, and Horn, Andreas, additional

Published
2023
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