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51. Design and methodology of the screening for CKD among older patients across Europe (SCOPE) study: a multicenter cohort observational study

Author: Corsonello, Andrea, Tap, Lisanne, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Zoccali, Carmine, Kostka, Tomasz, Guligowska, Agnieszka, Mattace-Raso, Francesco, Gil, Pedro, Fuentes, Lara Guardado, Meltzer, Itshak, Yehoshua, Ilan, Formiga-Perez, Francesc, Moreno-González, Rafael, Weingart, Christian, Freiberger, Ellen, Ärnlöv, Johan, Carlsson, Axel C., Bustacchini, Silvia, Lattanzio, Fabrizia, and on behalf of SCOPE investigators
Published: 2018
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52. Entwicklung von Lehre und Ausbildung in der Geriatrie

Author: Roller-Wirnsberger, Regina
Published: 2017
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53. Muscle power and nutrition

Author: Eglseer, Doris, Poglitsch, Ruth, and Roller-Wirnsberger, Regina Elisabeth
Published: 2016
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54. Management älterer Patienten nach Organtransplantation

Author: Roller-Wirnsberger, Regina Elisabeth and Wirnsberger, Gerhard Hubert
Published: 2016
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55. How to Publish Medical Humanities in Geriatrics and Gerontology Journals

Author: Clarfield, A. Mark, primary, O'Neil, Desmond, additional, and Roller-Wirnsberger, Regina, additional
Published: 2022
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56. The relevance of geriatric assessments on the association between chronic kidney disease stages and mortality among older people : A secondary analysis of a multicentre cohort study

Author: Corsonello, Andrea, Soraci, Luca, Ärnlöv, Johan, Carlsson, Axel C., Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Mattace-Raso, Francesco, Tap, Lisanne, Rudholm Feldreich, Tobias, Lattanzio, Fabrizia, Corsonello, Andrea, Soraci, Luca, Ärnlöv, Johan, Carlsson, Axel C., Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Mattace-Raso, Francesco, Tap, Lisanne, Rudholm Feldreich, Tobias, and Lattanzio, Fabrizia
Abstract: Background: age-adapted definition of chronic kidney disease (CKD) does not take individual risk factors into account. We aimed at investigating whether functional impairments influence CKD stage at which mortality increases among older people. Methods: our series consisted of 2,372 outpatients aged 75 years or more enrolled in a multicentre international prospective cohort study. The study outcome was 24-month mortality. Kidney function was assessed by estimated glomerular filtration rate (eGFR) and albumin-to-creatinine ratio (ACR). Geriatric assessments included handgrip strength, short physical performance battery (SPPB), cognitive impairment, dependency in basic activities of daily living (BADL) and risk of malnutrition. Analysis was carried out by Cox regression, before and after stratification by individual functional impairments. Survival trees including kidney function and functional impairments were also investigated, and their predictivity assessed by C-index. Results: overall, mortality was found to increase starting from eGFR = 30-44.9 ml/min/1.73 m2 (hazard ratio [HR] = 3.28, 95% confidence interval [CI] = 1.81-5.95) to ACR = 30-300 mg/g (HR = 1.96, 95%CI = 1.23-3.10). However, in survival trees, an increased risk of mortality was observed among patients with impaired handgrip and eGFR = 45-59.9 ml/min/1.73 m2, as well as patients with ACR < 30 mg/g and impaired handgrip and SPPB. Survival tree leaf node membership had greater predictive accuracy (C-index = 0.81, 95%CI = 0.78-0.84 for the eGFR survival tree and C-index = 0.77, 95%CI = 0.71-0.81 for the ACR survival tree) in comparison with that of individual measures of kidney function. Conclusions: physical performance helps to identify a proportion of patients at an increased risk of mortality despite a mild-moderate impairment in kidney function and improves predictive accuracy of individual measures of kidney function. © 2022 The Author(s). Published by Oxford University Press on behalf of the B
Published: 2022
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57. Interactions Between EIP on AHA Reference Sites and Action Groups to Foster Digital Innovation of Health and Care in European Regions

Author: Illario, Maddalena, De Luca, Vincenzo, Onorato, Gabrielle, Tramontano, Giovanni, Carriazo, Ana Maria, Roller-Wirnsberger, Regina Elisabeth, Apostolo, Joao, Eklund, Patrik, Goswami, Nandu, Iaccarino, Guido, Triassi, Maria, Farrell, John, Bousquet, Jean, Illario, Maddalena, De Luca, Vincenzo, Onorato, Gabrielle, Tramontano, Giovanni, Carriazo, Ana Maria, Roller-Wirnsberger, Regina Elisabeth, Apostolo, Joao, Eklund, Patrik, Goswami, Nandu, Iaccarino, Guido, Triassi, Maria, Farrell, John, and Bousquet, Jean
Abstract: The article describes some of the achievements of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), after eight years in operation. These results were achieved thanks to the collaborative work of the action groups (AGs) and reference sites (RSs). RS regional ecosystems include key organisations committed to investing in innovation to foster active and healthy ageing. The AGs are groups of professionals committed to sharing their knowledge and skills in active and healthy ageing. This article reports on the approach used by the EIP on AHA to bring together experts and regions in identifying and addressing these challenges. Synergies between AGs offered substantial support to RSs, allowing regional health and care priorities and challenges to be identified and pursued through AG commitments. Building upon the experiences of the EIP on AHA, the Reference Sites Collaborative Network has set up a number of thematic action groups that bring together multidisciplinary experts from across Europe to address the main health and social care challenges at regional, national and European level.
Published: 2022
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58. Inflammaging and Blood Pressure Profiles in Late Life:The Screening for CKD among Older People across Europe (SCOPE) Study

Author: Tap, Lisanne, Corsonello, Andrea, Di Rosa, Mirko, Fabbietti, Paolo, Formiga, Francesc, Moreno-González, Rafael, Ärnlöv, Johan, Carlsson, Axel C., Polinder-Bos, Harmke A., Roller-Wirnsberger, Regina E., Wirnsberger, Gerhard H., Kostka, Tomasz, Guligowska, Agnieszka, Artzi-Medvedik, Rada, Yehoshua, Ilan, Weingart, Christian, Sieber, Cornel C., Gil, Pedro, Lainez Martinez, Sara, Lattanzio, Fabrizia, Mattace-Raso, Francesco U.S., Tap, Lisanne, Corsonello, Andrea, Di Rosa, Mirko, Fabbietti, Paolo, Formiga, Francesc, Moreno-González, Rafael, Ärnlöv, Johan, Carlsson, Axel C., Polinder-Bos, Harmke A., Roller-Wirnsberger, Regina E., Wirnsberger, Gerhard H., Kostka, Tomasz, Guligowska, Agnieszka, Artzi-Medvedik, Rada, Yehoshua, Ilan, Weingart, Christian, Sieber, Cornel C., Gil, Pedro, Lainez Martinez, Sara, Lattanzio, Fabrizia, and Mattace-Raso, Francesco U.S.
Abstract: The neutrophil-to-lymphocyte ratio (NLR) is a marker for systemic inflammation. Since inflammation plays a relevant role in vascular aging, the aim of this study was to investigate whether NLR is associated with blood pressure profiles in older adults. This study was performed within the framework of the SCOPE study including 2461 outpatients aged 75 years and over. Mean blood pressure values, namely systolic blood pressure (SBP), diastolic blood pressure (DBP) and pulse pressure (PP) were investigated across tertiles of NLR. Change in blood pressure levels in 2 years of follow-up were compared across categories of baseline NLR. Data of 2397 individuals were used, of which 1854 individuals had hypertension. Mean values of blood pressure did not differ across categories of baseline NLR in individuals without hypertension. Individuals with hypertension with a high-range NLR had lower SBP and PP when compared to those in low-range NLR (mean difference SBP −2.94 mmHg, p = 0.032 and PP −2.55 mmHg, p = 0.030). Mean change in blood pressure in 2 years did only slightly differ in non-clinically relevant ranges, when compared across tertiles of baseline NLR. NLR as a marker of inflammaging was not associated with unfavorable blood pressure profiles in older individuals with or without hypertension.
Published: 2022

59. The relevance of geriatric assessments on the association between chronic kidney disease stages and mortality among older people:a secondary analysis of a multicentre cohort study

Author: Corsonello, Andrea, Soraci, Luca, Ärnlöv, Johan, Carlsson, Axel C., Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Mattace-Raso, Francesco, Tap, Lisanne, Formiga, Francesc, Moreno-González, Rafael, Kostka, Tomasz, Guligowska, Agnieszka, Artzi-Medvedik, Rada, Melzer, Itshak, Weingart, Christian, Sieber, Cornell, Lattanzio, Fabrizia, Corsonello, Andrea, Soraci, Luca, Ärnlöv, Johan, Carlsson, Axel C., Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Mattace-Raso, Francesco, Tap, Lisanne, Formiga, Francesc, Moreno-González, Rafael, Kostka, Tomasz, Guligowska, Agnieszka, Artzi-Medvedik, Rada, Melzer, Itshak, Weingart, Christian, Sieber, Cornell, and Lattanzio, Fabrizia
Abstract: BACKGROUND: age-adapted definition of chronic kidney disease (CKD) does not take individual risk factors into account. We aimed at investigating whether functional impairments influence CKD stage at which mortality increases among older people. METHODS: our series consisted of 2,372 outpatients aged 75 years or more enrolled in a multicentre international prospective cohort study. The study outcome was 24-month mortality. Kidney function was assessed by estimated glomerular filtration rate (eGFR) and albumin-to-creatinine ratio (ACR). Geriatric assessments included handgrip strength, short physical performance battery (SPPB), cognitive impairment, dependency in basic activities of daily living (BADL) and risk of malnutrition. Analysis was carried out by Cox regression, before and after stratification by individual functional impairments. Survival trees including kidney function and functional impairments were also investigated, and their predictivity assessed by C-index. RESULTS: overall, mortality was found to increase starting from eGFR = 30-44.9 ml/min/1.73 m2 (hazard ratio [HR] = 3.28, 95% confidence interval [CI] = 1.81-5.95) to ACR = 30-300 mg/g (HR = 1.96, 95%CI = 1.23-3.10). However, in survival trees, an increased risk of mortality was observed among patients with impaired handgrip and eGFR = 45-59.9 ml/min/1.73 m2, as well as patients with ACR < 30 mg/g and impaired handgrip and SPPB. Survival tree leaf node membership had greater predictive accuracy (C-index = 0.81, 95%CI = 0.78-0.84 for the eGFR survival tree and C-index = 0.77, 95%CI = 0.71-0.81 for the ACR survival tree) in comparison with that of individual measures of kidney function. CONCLUSIONS: physical performance helps to identify a proportion of patients at an increased risk of mortality despite a mild-moderate impairment in kidney function and improves predictive accuracy of individual measures of kidney function.
Published: 2022

60. Multicomponent intervention to prevent mobility disability in frail older adults: randomised controlled trial (SPRINTT project)

Author: Bernabei, Roberto, primary, Landi, Francesco, additional, Calvani, Riccardo, additional, Cesari, Matteo, additional, Del Signore, Susanna, additional, Anker, Stefan D, additional, Bejuit, Raphael, additional, Bordes, Philippe, additional, Cherubini, Antonio, additional, Cruz-Jentoft, Alfonso J, additional, Di Bari, Mauro, additional, Friede, Tim, additional, Gorostiaga Ayestarán, Carmen, additional, Goyeau, Harmonie, additional, Jónsson, Pálmi V, additional, Kashiwa, Makoto, additional, Lattanzio, Fabrizia, additional, Maggio, Marcello, additional, Mariotti, Luca, additional, Miller, Ram R, additional, Rodriguez-Mañas, Leocadio, additional, Roller-Wirnsberger, Regina, additional, Rýznarová, Ingrid, additional, Scholpp, Joachim, additional, Schols, Annemie M W J, additional, Sieber, Cornel C, additional, Sinclair, Alan J, additional, Skalska, Anna, additional, Strandberg, Timo, additional, Tchalla, Achille, additional, Topinková, Eva, additional, Tosato, Matteo, additional, Vellas, Bruno, additional, von Haehling, Stephan, additional, Pahor, Marco, additional, Roubenoff, Ronenn, additional, and Marzetti, Emanuele, additional
Published: 2022
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61. Interactions Between EIP on AHA Reference Sites and Action Groups to Foster Digital Innovation of Health and Care in European Regions

Author: Illario, Maddalena, primary, De Luca, Vincenzo, additional, Onorato, Gabrielle, additional, Tramontano, Giovanni, additional, Carriazo, Ana Maria, additional, Roller-Wirnsberger, Regina Elisabeth, additional, Apostolo, Joao, additional, Eklund, Patrik, additional, Goswami, Nandu, additional, Iaccarino, Guido, additional, Triassi, Maria, additional, Farrell, John, additional, and Bousquet, Jean, additional
Published: 2022
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62. Anwendung von Biologika bei allergischen und Typ-2-entzündlichen Erkrankungen in der aktuellen Covid-19-Pandemiea, b, c

Author: Klimek, Ludger, Pfaar, Oliver, Worm, Margitta, Eiwegger, Thomas, Hagemann, Jan, Ollert, Markus, Untersmayr, Eva, Hoffmann-Sommergruber, Karin, Vultaggio, Alessandra, Agache, Ioana, Bavbek, Sevim, Bossios, Apostolos, Casper, Ingrid, Chan, Susan, Chatzipetrou, Alexia, Vogelberg, Christian, Firinu, Davide, Kauppi, Paula, Kolios, Antonios, Kothari, Akash, Matucci, Andrea, Palomares, Oscar, Szépfalusi, Zsolt, Pohl, Wolfgang, Hötzenecker, Wolfram, Rosenkranz, Alexander, Bergmann, Karl-Christian, Bieber, Thomas, Buhl, Roland, Buters, Jeroen, Darsow, Ulf, Keil, Thomas, Kleine-Tebbe, Jörg, Lau, Susanne, Maurer, Marcus, Merk, Hans, Mösges, Ralph, Saloga, Joachim, Staubach, Petra, Jappe, Uta, Rabe, Claus, Rabe, Uta, Vogelmeier, Claus, Biedermann, Tilo, Jung, Kirsten, Schlenter, Wolfgang, Ring, Johannes, Chaker, Adam, Wehrmann, Wolfgang, Becker, Sven, Freudelsperger, Laura, Mülleneisen, Norbert, Nemat, Katja, Czech, Wolfgang, Wrede, Holger, Brehler, Randolf, Fuchs, Thomas, Tomazic, Peter-Valentin, Aberer, Werner, Fink Wagner, Antje, Horak, Fritz, Wöhrl, Stefan, Niederberger-Leppin, Verena, Pali-Schöll, Isabella, Roller-Wirnsberger, Regina, Spranger, Otto, Valenta, Rudolf, Akdis, Mübecell, Matricardi, Paolo M., Spertini, François, Khaltaev, Nikolai, Michel, Jean-Pierre, Nicod, Larent, Schmid-Grendelmeier, Peter, Idzko, Marco, Hamelmann, Eckard, Jakob, Thilo, Werfel, Thomas, Wagenmann, Martin, Taube, Christian, Jensen-Jarolim, Erika, Korn, Stephanie, Hentges, Francois, Schwarze, Jürgen, O´Mahony, Liam, Knol, Edward, del Giacco, Stefano, Chivato, Tomás, Bousquet, Jean, Zuberbier, Torsten, Akdis, Cezmi, and Jutel, Marek
Subjects: Titel, SARS-CoV-2, Medizin, Immunology and Allergy, Omalizumab, Benralizumab, Dupilumab, Reslizumab, Covid-19, Telemedizin, Mepolizumab
Published: 2020

63. Diabetes, sarcopenia and chronic kidney disease; the screening for CKD among older people across Europe (SCOPE) study

Author: Formiga Pérez, Francesc, Moreno‑, González, Rafael, Corsonello, Andrea, Carlsson, Axel C., Ärnlöv, Johan, Mattace-Raso, Francesco, Kostka, Tomasz, Weingart, Christian, Roller-Wirnsberger, Regina, Tap, Lisanne, Guligowska, Agnieszka, Sieber, Cornel, Wirnsberger, Gerhard, Artzi-Medvedik, Rada, Yehoshua, Ilan, Giuli, Cinzia, Lattanzio, Fabrizia, and Corbella, Xavier
Subjects: Diabetis, Malalties del fetge, Chronic diseases, Diabetes, Malalties cròniques, Insuficiència renal, Renal insufficiency, Older people, human activities, Persones grans, Liver diseases
Abstract: ackground:Sarcopenia may be more present in older adults with diabetes (DM). Accordingly, we evaluated the prevalence of sarcopenia and its associated risk factors among community‑dwelling older adults with DM.Methods:A cross‑sectional analysis of older people living in the community was carried out. Participants (aged 75 years and more) came from an European multicenter prospective cohort (SCOPE study). Global geriatric assess‑ment including short physical performance battery, handgrip strength test and bioelectrical impedance analysis was performed. Sarcopenia was defined by the updated criteria of the European Working Group on Sarcopenia in Older People (EWGSOP2). Estimated glomerular filtration rate (eGFR) was calculated using Berlin Initiative Study (BIS) to define the stages of chronic kidney disease (CKD). Previous known DM was defined as physician‑diagnosed DM reg‑istered in the patient's medical record or the use of DM‑related medications. Hemoglobin A1c levels and specific DM therapies administered were collected. Time elapsed from the first diagnosis of DM was not collected and, therefore, was not included in the analyses.Results:A total of 1,420 subjects were evaluated with a median age of 79.0 (6.0) years, of which 804 (56.6%) were women and 615 (43.3%) men; 315 (22.2%) participants had prior DM diagnosis, with a median age of 80.0 (6.0), 146 (46.3%) were women. Using EWGSOP2 definition, 150 (10.6%) participants in the SCOPE study met diagnostic criteria for sarcopenia. Participants without diabetes had more often normal results in the 3 sarcopenia components than participants with diabetes [887 (80.31%) vs. 227 (72.1%), p=0.002], highlighting higher percentages of severe sarco‑penia in participants with diabetes [27 (8.6%) vs. 58 (5.2%), p=0.028]. Confirmed or severe sarcopenia was detected in 41 (13%) participants with diabetes and 109 (9.8%) participants without diabetes (p=0.108). According to BIS equa‑tion, sarcopenia was not significantly more prevalent in the more advanced stages of CKD (p=0.845). In multivariate analyses, older age (odds ratios [OR], 1.17; 95% confidence interval [CI], 1.08-1.27), and lower body mass index (OR, 0.79; 95% CI, 0.71-0.89 were associated with the presence of sarcopenia.Conclusions:One tenth of all older community‑dwelling subjects have sarcopenia. Older age and being thinner, but not worse renal function, were associated with higher prevalence of sarcopenia in older older adults with diabetes.
Published: 2022

64. Chefs in Future Integrated Healthcare – Current State and Innovation Needs: A First Overview of the NECTAR Project (aN Eu Curriculum for Chef gasTro-Engineering in Primary Food Care)

Author: Winters, Marjolein, primary, Wagner, Valentina, additional, Patalano, Roberta, additional, Lindner, Sonja, additional, Alvino, Serena, additional, Roller-Wirnsberger, Regina, additional, Müller-Riedlhuber, Heidemarie, additional, Pais, Sandra, additional, Borriello, Matilde, additional, Farrel, John, additional, Vlaemynck, Geertrui, additional, van Gemst, Martijn, additional, Geurden, Bart, additional, Van den Wijngaert, Lobke, additional, Goossens, Edwig, additional, Illario, Maddalena, additional, and Herzog, Carolin, additional
Published: 2022
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65. Usability Evaluation after a 6-month Tablet-based Dementia Training Program by People with Alzheimer’s Disease, Relatives, and Dementia Trainers

Author: Zuschnegg, Julia, primary, Schuessler, Sandra, additional, Paletta, Lucas, additional, Russegger, Silvia, additional, Fellner, Maria, additional, Ploder, Karin, additional, Strobl, Bernhard, additional, Sekulic, Maja, additional, Koini, Marisa, additional, M Hofmarcher Holzhacker, Maria, additional, and Roller Wirnsberger, Regina, additional
Published: 2022
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66. Clinical Interventions to Improve Nutritional Care in Older Adults and Patients in Primary Healthcare – A Scoping Review of Current Practices of Health Care Practitioners

Author: Lindner-Rabl, Sonja, primary, Wagner, Valentina, additional, Matijevic, Andreas, additional, Herzog, Carolin, additional, Lampl, Christina, additional, Traub, Julia, additional, and Roller-Wirnsberger, Regina, additional
Published: 2022
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67. Communication during the COVID-19 Pandemic: Evaluation-Study on Self-Perceived Competences and Views of Health Care Professionals

Author: Singler, Katrin, Martinez-Velilla, Nicolas, Jan, Schildmann, Bischoff-Ferrari, Heike A., Roller-Wirnsberger, Regina Elisabeth, Attier-Zmudka, Jadwiga, Jones, Christopher A., and Gordon, Adam L.
Subjects: Communication, COVID-19, older adults, training
Abstract: PurposeThe aims of this study were to describe communication experiences while wearing a mask during COVID-19 pandemic in 2020, in order to identify possible mask-related barriers to COVID-19-adapted communications and to investigate whether the ABC mnemonic (A: Attend Mindfully; B: Behave Calmly; C: Communicate Clearly) might address these.MethodsThis study was a cross-sectional, voluntary, web-based survey between January and February 2021. A 22-item survey was developed using the Surveymonkey platform and question-styles were varied to include single choice and Likert scales. The respondents were also asked to view a short video presentation, which outlined the ABC mnemonic. CHERRIES (Checklist for Reporting Results of Internet E-Surveys) was used to ensure completeness of reporting. Diverging stacked bar charts were created to illustrate Likert scale responses.ResultsWe received 226 responses. The respondents were mostly women (60.2%) and the majority worked in a teaching hospital (64.6%). The majority of the respondents indicated issues related to lack of time during clinical encounters, uncertainty about how to adapt communication, lack of personal protective equipment, lack of communication skills and lack of information about how to adapt their own communication skills. In addition, the participants indicated acknowledging emotions and providing information using clear, specific, unambiguous, and consistent lay language while wearing a mask were among the main communication challenges created during the COVID-19 pandemic. Finally, the study showed significantly improved self-perceived competency regarding key communication after watching the short video presentation. ConclusionEffective communication in medical encounters requires both verbal and nonverbal skills.
Published: 2021

68. Evaluating the effectiveness and risks of oral anticoagulant treatments in multimorbid frail older subjects with atrial fibrillation using the multidimensional prognostic index

Author: Veronese, Nicola, Argusti, Alessandra, Canepa, Elisabetta, Polidori, Maria Cristina, Maggi, Stefania, Strandberg, Timo, Pilotto, Alberto, Marchionni, Nicolò, Durando, Mario, Ferrara, Nicola, Bò, Mario, Barbagallo, Mario, Ruotolo, Giovanni, Heppner, Hans Jurgen, Bahrmann, Philipp, Roller-Wirnsberger, Regina, Pedro, Gil Gregorio, Cruz-Jentoft, Alfonso, da Silva, Pedro Marques, Gruner, Heidi, Berg, Nicolas, Topinkova, Eva, Matejovska-Kubesova, Hana, Nieminen, Tuomo, Pikkarainen, Laura, Rossinen, Juhani, Kearney-Schwartz, Anna, Rewiuk, Krzyszof, Mattace-Raso, Francesco, Olexa, Peter, Internal Medicine, Veronese, Nicola, Argusti, Alessandra, Canepa, Elisabetta, Polidori, Maria Cristina, Maggi, Stefania, Strandberg, Timo, Pilotto, Alberto, Marchionni, Nicolò, Durando, Mario, Ferrara, Nicola, Bò, Mario, Barbagallo, Mario, Ruotolo, Giovanni, Heppner, Hans Jurgen, Bahrmann, Philipp, Roller-Wirnsberger, Regina, Pedro, Gil Gregorio, Cruz-Jentoft, Alfonso, da Silva, Pedro Marque, Gruner, Heidi, Berg, Nicola, Topinkova, Eva, Matejovska-Kubesova, Hana, Nieminen, Tuomo, Pikkarainen, Laura, Rossinen, Juhani, Kearney-Schwartz, Anna, Rewiuk, Krzyszof, Mattace-Raso, Francesco, and Olexa, Peter
Subjects: medicine.medical_specialty, Muldimensional Prognostic Index, Population, law.invention, 03 medical and health sciences, Elderly, 0302 clinical medicine, Randomized controlled trial, law, Internal medicine, Atrial Fibrillation, medicine, Risk of mortality, 030212 general & internal medicine, Medical prescription, education, Anticoagulants, Frailty, education.field_of_study, business.industry, Anticoagulant, Warfarin, Atrial fibrillation, medicine.disease, Relative risk, Observational study, Geriatrics and Gerontology, business, Gerontology, 030217 neurology & neurosurgery, medicine.drug
Abstract: Background: Previous studies suggested that a different risk of mortality may influence the oral anticoagulant prescription in older patients with atrial fibrillation (AF). Recently, the Multidimensional Prognostic Index (MPI) demonstrated a high grade of accuracy, calibration and feasibility to predict mortality in hospitalized and community-dwelling older people. Prognostic information, as calculated by the MPI, however, is not included in the decision algorithm of treatments in older patients with AF Purpose: The aim of this international multicenter prospective observational study was to evaluate whether a different prognostic profile, as determined by the MPI, is associated with different treatments for AF (no treatment vs oral anticoagulants) and differences in the main outcomes, i.e., mortality, major thromboembolic events and side effects. Materials and methods: Older hospitalized patients (age ≥ 65 years) with non-valvular AF will be consecutively enrolled in an European, cross-national, prospective, observational study. At baseline, functional and clinical information will be collected to calculate the MPI, CHA2DS2-VASc score, HAS-BLED score, pharmacological treatments (and the compliance during follow-up) and main and secondary diagnoses. During the 12-month follow-up period, information on survival, major thromboembolic events and major bleeding will be collected. For these aims, a sample size of 3000 people was deemed as sufficient. Conclusions: The EUROSAF study has the main objective of evaluating in a population of hospitalized older subjects with AF the clinical benefit/risk ratio of the oral anticoagulant treatments in terms of mortality, major thromboembolic events and bleeding side-effects, giving important information regarding the appropriate prescription of anticoagulant therapy in this population. ClinicalTrials.gov Identifier: NCT02973984.
Published: 2018

69. Prevalence and associations of potentially inappropriate prescriptions in Austrian nursing home residents: secondary analysis of a cross-sectional study

Author: Mann, Eva, Haastert, Burkhard, Böhmdorfer, Birgit, Frühwald, Thomas, Iglseder, Bernhard, Roller-Wirnsberger, Regina, and Meyer, Gabriele
Published: 2013
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70. Intrinsic Capacity Predicts Negative Health Outcomes in Older Adults

Author: Stolz, Erwin, primary, Mayerl, Hannes, additional, Freidl, Wolfgang, additional, Roller-Wirnsberger, Regina, additional, and Gill, Thomas M, additional
Published: 2021
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71. Teaching geriatric medicine through gamification: a tool for enhancing postgraduate education in geriatric medicine

Author: Schlögl, Mathias, primary, Roller-Wirnsberger, Regina Elisabeth, additional, Hernes, Susanne Sørensen, additional, Perkisas, Stany, additional, Bakken, Marit Stordal, additional, Miot, Stéphanie, additional, Balci, Cafer, additional, Dani, Melanie, additional, Pajulammi, Hanna, additional, Piaggi, Paolo, additional, Drenth-van Maanen, Clara, additional, and Singler, Katrin, additional
Published: 2021
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72. ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice

Author: Bousquet, Jean Anto, Josep M. Bachert, Claus Haahtela, Tari and Zuberbier, Torsten Czarlewski, Wienczyslawa Bedbrook, Anna and Bosnic-Anticevich, Sinthia Walter Canonica, G. Cardona, Victoria Costa, Elisio Cruz, Alvaro A. Erhola, Marina and Fokkens, Wytske J. Fonseca, Joao A. Illario, Maddalena and Ivancevich, Juan-Carlos Jutel, Marek Klimek, Ludger Kuna, Piotr Kvedariene, Violeta Le, L. T. T. Larenas-Linnemann, Desiree E. Laune, Daniel Lourenco, Olga M. Melen, Erik and Mullol, Joaquim Niedoszytko, Marek Odemyr, Mikaela Okamoto, Yoshitaka Papadopoulos, Nikos G. Patella, Vincenzo Pfaar, Oliver Pham-Thi, Nhan Rolland, Christine Samolinski, Boleslaw Sheikh, Aziz Sofiev, Mikhail Suppli Ulrik, Charlotte Todo-Bom, Ana Tomazic, Peter-Valentin and Toppila-Salmi, Sanna Tsiligianni, Ioanna Valiulis, Arunas and Valovirta, Erkka Ventura, Maria-Teresa Walker, Samantha and Williams, Sian Yorgancioglu, Arzu Agache, Ioana Akdis, Cezmi A. Almeida, Rute Ansotegui, Ignacio J. Annesi-Maesano, Isabella Arnavielhe, Sylvie Basagana, Xavier D. Bateman, Eric Bedard, Annabelle Bedolla-Barajas, Martin Becker, Sven and Bennoor, Kazi S. Benveniste, Samuel Bergmann, Karl C. and Bewick, Michael Bialek, Slawomir E. Billo, Nils and Bindslev-Jensen, Carsten Bjermer, Leif Blain, Hubert Bonini, Matteo Bonniaud, Philippe Bosse, Isabelle Bouchard, Jacques and Boulet, Louis-Philippe Bourret, Rodolphe Boussery, Koen and Braido, Fluvio Briedis, Vitalis Briggs, Andrew Brightling, Christopher E. Brozek, Jan Brusselle, Guy Brussino, Luisa and Buhl, Roland Buonaiuto, Roland Calderon, Moises A. and Camargos, Paulo Camuzat, Thierry Caraballo, Luis Carriazo, Ana-Maria Carr, Warner Cartier, Christine Casale, Thomas and Cecchi, Lorenzo Cepeda Sarabia, Alfonso M. H. Chavannes, Niels and Chkhartishvili, Ekaterine Chu, Derek K. Cingi, Cemal and Correia de Sousa, Jaime Costa, David J. Courbis, Anne-Lise and Custovic, Adnan Cvetkosvki, Biljana D'Amato, Gennaro da Silva, Jane Dantas, Carina Dokic, Dejan Dauvilliers, Yves and De Feo, Giulia De Vries, Govert Devillier, Philippe Di Capua, Stefania Dray, Gerard Dubakiene, Ruta Durham, Stephen R. Dykewicz, Marc Ebisawa, Motohiro Gaga, Mina El-Gamal, Yehia Heffler, Enrico Emuzyte, Regina Farrell, John and Fauquert, Jean-Luc Fiocchi, Alessandro Fink-Wagner, Antje and Fontaine, Jean-Francois Fuentes Perez, Jose M. Gemicioglu, Bilun and Gamkrelidze, Amiran Garcia-Aymerich, Judith Gevaert, Philippe Gomez, Rene Maximiliano Gonzalez Diaz, Sandra and Gotua, Maia Guldemond, Nick A. Guzman, Maria-Antonieta and Hajjam, Jawad Huerta Villalobos, Yunuen R. Humbert, Marc and Iaccarino, Guido Ierodiakonou, Despo Iinuma, Tomohisa and Jassem, Ewa Joos, Guy Jung, Ki-Suck Kaidashev, Igor and Kalayci, Omer Kardas, Przemyslaw Keil, Thomas Khaitov, Musa and Khaltaev, Nikolai Kleine-Tebbe, Jorg Kouznetsov, Rostislav and Kowalski, Marek L. Kritikos, Vicky Kull, Inger La Grutta, Stefania Leonardini, Lisa Ljungberg, Henrik and Lieberman, Philip Lipworth, Brian Lodrup Carlsen, Karin C. and Lopes-Pereira, Catarina Loureiro, Claudia C. Louis, Renaud and Mair, Alpana Mahboub, Bassam Makris, Michael Malva, Joao and Manning, Patrick Marshall, Gailen D. Masjedi, Mohamed R. and Maspero, Jorge F. Carreiro-Martins, Pedro Makela, Mika and Mathieu-Dupas, Eve Maurer, Marcus De Manuel Keenoy, Esteban and Melo-Gomes, Elisabete Meltzer, Eli O. Menditto, Enrica and Mercier, Jacques Micheli, Yann Miculinic, Neven Mihaltan, Florin Milenkovic, Branislava Mitsias, Dimitirios I. Moda, Giuliana Mogica-Martinez, Maria-Dolores Mohammad, Yousser and Montefort, Steve Monti, Ricardo Morais-Almeida, Mario and Mosges, Ralph Munter, Lars Muraro, Antonella Murray, Ruth and Naclerio, Robert Napoli, Luigi Namazova-Baranova, Leyla and Neffen, Hugo Nekam, Kristoff Neou, Angelo Nordlund, Bjorn and Novellino, Ettore Nyembue, Dieudonne O'Hehir, Robyn and Ohta, Ken Okubo, Kimi Onorato, Gabrielle L. Orlando, Valentina Ouedraogo, Solange Palamarchuk, Julia Pali-Scholl, Isabella Panzner, Peter Park, Hae-Sim Passalacqua, Gianni and Pepin, Jean-Louis Paulino, Ema Pawankar, Ruby Phillips, Jim Picard, Robert Pinnock, Hilary Plavec, Davor Popov, Todor A. Portejoie, Fabienne Price, David Prokopakis, Emmanuel P. Psarros, Fotis Pugin, Benoit Puggioni, Francesca and Quinones-Delgado, Pablo Raciborski, Filip and Rajabian-Soderlund, Rojin Regateiro, Frederico S. Reitsma, Sietze Rivero-Yeverino, Daniela Roberts, Graham Roche, Nicolas Rodriguez-Zagal, Erendira Rolland, Christine and Roller-Wirnsberger, Regina E. Rosario, Nelson Romano, Antonino and Rottem, Menachem Ryan, Dermot Salimaki, Johanna and Sanchez-Borges, Mario M. Sastre, Joaquin Scadding, Glenis K. and Scheire, Sophie Schmid-Grendelmeier, Peter Schunemann, Holger J. and Sarquis Serpa, Faradiba Shamji, Mohamed Sisul, Juan-Carlos and Sofiev, Mikhail Sole, Dirceu Somekh, David Sooronbaev, Talant Sova, Milan Spertini Spranger, Otto Stellato, Cristiana Stelmach, Rafael Thibaudon, Michel To, Teresa and Toumi, Mondher Usmani, Omar Valero, Antonio A. Valenta, Rudolph Valentin-Rostan, Marylin Pereira, Marilyn Urrutia and van der Kleij, Rianne Van Eerd, Michiel Vandenplas, Olivier and Vasankari, Tuula Vaz Carneiro, Antonio Vezzani, Giorgio and Viart, Frederic Viegi, Giovanni Wallace, Dana Wagenmann, Martin Wang, De Yun Waserman, Susan Wickman, Magnus and Williams, Dennis M. Wong, Gary Wroczynski, Piotr Yiallouros, Panayiotis K. Yusuf, Osman M. Zar, Heather J. Zeng, Stephane and Zernotti, Mario E. Zhang, Luo Shan Zhong, Nan Zidarn, Mihaela
Abstract: Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed.
Published: 2021

73. Digital transformation of health and care in airway diseases from research to practice

Author: Bousquet, Jean, Anto, Josep M., Bachert, Claus, Haahtela, Tari, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Walter Canonica, G., Cardona, Victoria, Costa, Elisio, Cruz, Alvaro A., Erhola, Marina, Fokkens, Wytske J., Fonseca, Joao A., Illario, Maddalena, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T.T., Larenas-Linnemann, Désirée E., Laune, Daniel, Lourenço, Olga M., Melén, Erik, Mullol, Joaquim, Niedoszytko, Marek, Odemyr, Mikaëla, Okamoto, Yoshitaka, Papadopoulos, Nikos G., Patella, Vincenzo, Pfaar, Oliver, Pham-Thi, Nhân, Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Sofiev, Mikhail, Suppli Ulrik, Charlotte, Todo-Bom, Ana, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Ventura, Maria Teresa, Walker, Samantha, Williams, Sian, Yorgancioglu, Arzu, Agache, Ioana, Akdis, Cezmi A., Almeida, Rute, Ansotegui, Ignacio J., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagaña, Xavier, D. Bateman, Eric, Bédard, Annabelle, Bedolla-Barajas, Martin, Becker, Sven, Bennoor, Kazi S., Benveniste, Samuel, Bergmann, Karl C., Bewick, Michael, Bialek, Slawomir, E. Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Matteo, Bonniaud, Philippe, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis Philippe, Bourret, Rodolphe, Boussery, Koen, Braido, Fluvio, Briedis, Vitalis, Briggs, Andrew, Brightling, Christopher E., Brozek, Jan, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Buonaiuto, Roland, Calderon, Moises A., Camargos, Paulo, Camuzat, Thierry, Caraballo, Luis, Carriazo, Ana Maria, Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., H. Chavannes, Niels, Chkhartishvili, Ekaterine, Chu, Derek K., Cingi, Cemal, Correia de Sousa, Jaime, Costa, David J., Courbis, Anne Lise, Custovic, Adnan, Cvetkosvki, Biljana, D'Amato, Gennaro, da Silva, Jane, Dantas, Carina, Dokic, Dejan, Dauvilliers, Yves, De Feo, Giulia, De Vries, Govert, Devillier, Philippe, Di Capua, Stefania, Dray, Gerard, Dubakiene, Ruta, Durham, Stephen R., Dykewicz, Marc, Ebisawa, Motohiro, Gaga, Mina, El-Gamal, Yehia, Heffler, Enrico, Emuzyte, Regina, Farrell, John, Fauquert, Jean Luc, Fiocchi, Alessandro, Fink-Wagner, Antje, Fontaine, Jean François, Fuentes Perez, José M., Gemicioğlu, Bilun, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gevaert, Philippe, Gomez, René Maximiliano, González Diaz, Sandra, Gotua, Maia, Guldemond, Nick A., Guzmán, Maria Antonieta, Hajjam, Jawad, Huerta Villalobos, Yunuen R., Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Iinuma, Tomohisa, Jassem, Ewa, Joos, Guy, Jung, Ki Suck, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Musa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kouznetsov, Rostislav, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, La Grutta, Stefania, Leonardini, Lisa, Ljungberg, Henrik, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Lopes-Pereira, Catarina, Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Mahboub, Bassam, Makris, Michaël, Malva, Joao, Manning, Patrick, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Carreiro-Martins, Pedro, Makela, Mika, Mathieu-Dupas, Eve, Maurer, Marcus, De Manuel Keenoy, Esteban, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Mercier, Jacques, Micheli, Yann, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mitsias, Dimitirios I., Moda, Giuliana, Mogica-Martinez, Maria Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mösges, Ralph, Münter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leyla, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Nordlund, Björn, Novellino, Ettore, Nyembue, Dieudonné, O'Hehir, Robyn, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle L., Orlando, Valentina, Ouedraogo, Solange, Palamarchuk, Julia, Pali-Schöll, Isabella, Panzner, Peter, Park, Hae Sim, Passalacqua, Gianni, Pépin, Jean Louis, Paulino, Ema, Pawankar, Ruby, Phillips, Jim, Picard, Robert, Pinnock, Hilary, Plavec, Davor, Popov, Todor A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Psarros, Fotis, Pugin, Benoit, Puggioni, Francesca, Quinones-Delgado, Pablo, Raciborski, Filip, Rajabian-Söderlund, Rojin, Regateiro, Frederico S., Reitsma, Sietze, Rivero-Yeverino, Daniela, Roberts, Graham, Roche, Nicolas, Rodriguez-Zagal, Erendira, Roller-Wirnsberger, Regina E., Rosario, Nelson, Romano, Antonino, Rottem, Menachem, Ryan, Dermot, Salimäki, Johanna, Sanchez-Borges, Mario M., Sastre, Joaquin, Scadding, Glenis K., Scheire, Sophie, Schmid-Grendelmeier, Peter, Schünemann, Holger J., Sarquis Serpa, Faradiba, Shamji, Mohamed, Sisul, Juan Carlos, Solé, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spertini, François, Spranger, Otto, Stellato, Cristiana, Stelmach, Rafael, Thibaudon, Michel, To, Teresa, Toumi, Mondher, Usmani, Omar, Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, Pereira, Marilyn Urrutia, van der Kleij, Rianne, Van Eerd, Michiel, Vandenplas, Olivier, Vasankari, Tuula, Vaz Carneiro, Antonio, Vezzani, Giorgio, Viart, Frédéric, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yusuf, Osman M., Zar, Heather J., Zeng, Stéphane, Zernotti, Mario E., Zhang, Luo, Shan Zhong, Nan, Zidarn, Mihaela, and NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Subjects: ARIA, rhinitis, CARAT, MASK, Immunology, Immunology and Allergy, asthma, digital transformation of health and care
Abstract: Funding: MA reports personal fees from POCI-01-0145-FEDER-029130 mINSPIRERS—mHealth to measure and improve adherence to medication in chronic obstructive respiratory diseases—generalization and evaluation of gamification, peer support and advanced image processing technologies from ERDF (European Regional Development Fund) funded by the COMPETE2020 and by National Funds through FCT (Fundação para a Ciência e a Tecnologia)… Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed. publishersversion published
Published: 2021

74. ARIA digital anamorphosis : Digital transformation of health and care in airway diseases from research to practice

Author: Bousquet, Jean, Anto, Josep M., Bachert, Claus, Haahtela, Tari, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Walter Canonica, G., Cardona, Victoria, Costa, Elisio, Cruz, Alvaro A., Erhola, Marina, Fokkens, Wytske J., Fonseca, Joao A., Illario, Maddalena, Ivancevich, Juan-Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T. T., Larenas-Linnemann, Desiree E., Laune, Daniel, Lourenco, Olga M., Melen, Erik, Mullol, Joaquim, Niedoszytko, Marek, Odemyr, Mikaela, Okamoto, Yoshitaka, Papadopoulos, Nikos G., Patella, Vincenzo, Pfaar, Oliver, Pham-Thi, Nhan, Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Sofiev, Mikhail, Suppli Ulrik, Charlotte, Todo-Bom, Ana, Tomazic, Peter-Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Ventura, Maria-Teresa, Walker, Samantha, Williams, Sian, Yorgancioglu, Arzu, Agache, Ioana, Akdis, Cezmi A., Almeida, Rute, Ansotegui, Ignacio J., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagana, Xavier, D. Bateman, Eric, Bedard, Annabelle, Bedolla-Barajas, Martin, Becker, Sven, Bennoor, Kazi S., Benveniste, Samuel, Bergmann, Karl C., Bewick, Michael, Bialek, Slawomir, E. Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Matteo, Bonniaud, Philippe, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis-Philippe, Bourret, Rodolphe, Boussery, Koen, Braido, Fluvio, Briedis, Vitalis, Briggs, Andrew, Brightling, Christopher E., Brozek, Jan, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Buonaiuto, Roland, Calderon, Moises A., Camargos, Paulo, Camuzat, Thierry, Caraballo, Luis, Carriazo, Ana-Maria, Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., H. Chavannes, Niels, Chkhartishvili, Ekaterine, Chu, Derek K., Cingi, Cemal, Correia de Sousa, Jaime, Costa, David J., Courbis, Anne-Lise, Custovic, Adnan, Cvetkosvki, Biljana, D'Amato, Gennaro, da Silva, Jane, Dantas, Carina, Dokic, Dejan, Dauvilliers, Yves, De Feo, Giulia, De Vries, Govert, Devillier, Philippe, Di Capua, Stefania, Dray, Gerard, Dubakiene, Ruta, Durham, Stephen R., Dykewicz, Marc, Ebisawa, Motohiro, Gaga, Mina, El-Gamal, Yehia, Heffler, Enrico, Emuzyte, Regina, Farrell, John, Fauquert, Jean-Luc, Fiocchi, Alessandro, Fink-Wagner, Antje, Fontaine, Jean-Francois, Fuentes Perez, Jose M., Gemicioglu, Bilun, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gevaert, Philippe, Gomez, Rene Maximiliano, Gonzalez Diaz, Sandra, Gotua, Maia, Guldemond, Nick A., Guzman, Maria-Antonieta, Hajjam, Jawad, Huerta Villalobos, Yunuen R., Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Iinuma, Tomohisa, Jassem, Ewa, Joos, Guy, Jung, Ki-Suck, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Musa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kouznetsov, Rostislav, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, La Grutta, Stefania, Leonardini, Lisa, Ljungberg, Henrik, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Lopes-Pereira, Catarina, Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Mahboub, Bassam, Makris, Michael, Malva, Joao, Manning, Patrick, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Carreiro-Martins, Pedro, Makela, Mika, Mathieu-Dupas, Eve, Maurer, Marcus, De Manuel Keenoy, Esteban, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Mercier, Jacques, Micheli, Yann, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mitsias, Dimitirios I., Moda, Giuliana, Mogica-Martinez, Maria-Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mosges, Ralph, Munter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leyla, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Nordlund, Bjorn, Novellino, Ettore, Nyembue, Dieudonne, O'Hehir, Robyn, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle L., Orlando, Valentina, Ouedraogo, Solange, Palamarchuk, Julia, Pali-Scholl, Isabella, Panzner, Peter, Park, Hae-Sim, Passalacqua, Gianni, Pepin, Jean-Louis, Paulino, Ema, Pawankar, Ruby, Phillips, Jim, Picard, Robert, Pinnock, Hilary, Plavec, Davor, Popov, Todor A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Psarros, Fotis, Pugin, Benoit, Puggioni, Francesca, Quinones-Delgado, Pablo, Raciborski, Filip, Rajabian-Soderlund, Rojin, Regateiro, Frederico S., Reitsma, Sietze, Rivero-Yeverino, Daniela, Roberts, Graham, Roche, Nicolas, Rodriguez-Zagal, Erendira, Roller-Wirnsberger, Regina E., Rosario, Nelson, Romano, Antonino, Rottem, Menachem, Ryan, Dermot, Salimaki, Johanna, Sanchez-Borges, Mario M., Sastre, Joaquin, Scadding, Glenis K., Scheire, Sophie, Schmid-Grendelmeier, Peter, Schunemann, Holger J., Sarquis Serpa, Faradiba, Shamji, Mohamed, Sisul, Juan-Carlos, Sole, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spertini, Spranger, Otto, Stellato, Cristiana, Stelmach, Rafael, Thibaudon, Michel, To, Teresa, Toumi, Mondher, Usmani, Omar, Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, Pereira, Marilyn Urrutia, van der Kleij, Rianne, Van Eerd, Michiel, Vandenplas, Olivier, Vasankari, Tuula, Vaz Carneiro, Antonio, Vezzani, Giorgio, Viart, Frederic, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yusuf, Osman M., Zar, Heather J., Zeng, Stephane, Zernotti, Mario E., Zhang, Luo, Shan Zhong, Nan, Zidarn, Mihaela, Bousquet, Jean, Anto, Josep M., Bachert, Claus, Haahtela, Tari, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Walter Canonica, G., Cardona, Victoria, Costa, Elisio, Cruz, Alvaro A., Erhola, Marina, Fokkens, Wytske J., Fonseca, Joao A., Illario, Maddalena, Ivancevich, Juan-Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T. T., Larenas-Linnemann, Desiree E., Laune, Daniel, Lourenco, Olga M., Melen, Erik, Mullol, Joaquim, Niedoszytko, Marek, Odemyr, Mikaela, Okamoto, Yoshitaka, Papadopoulos, Nikos G., Patella, Vincenzo, Pfaar, Oliver, Pham-Thi, Nhan, Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Sofiev, Mikhail, Suppli Ulrik, Charlotte, Todo-Bom, Ana, Tomazic, Peter-Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Ventura, Maria-Teresa, Walker, Samantha, Williams, Sian, Yorgancioglu, Arzu, Agache, Ioana, Akdis, Cezmi A., Almeida, Rute, Ansotegui, Ignacio J., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagana, Xavier, D. Bateman, Eric, Bedard, Annabelle, Bedolla-Barajas, Martin, Becker, Sven, Bennoor, Kazi S., Benveniste, Samuel, Bergmann, Karl C., Bewick, Michael, Bialek, Slawomir, E. Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Matteo, Bonniaud, Philippe, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis-Philippe, Bourret, Rodolphe, Boussery, Koen, Braido, Fluvio, Briedis, Vitalis, Briggs, Andrew, Brightling, Christopher E., Brozek, Jan, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Buonaiuto, Roland, Calderon, Moises A., Camargos, Paulo, Camuzat, Thierry, Caraballo, Luis, Carriazo, Ana-Maria, Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., H. Chavannes, Niels, Chkhartishvili, Ekaterine, Chu, Derek K., Cingi, Cemal, Correia de Sousa, Jaime, Costa, David J., Courbis, Anne-Lise, Custovic, Adnan, Cvetkosvki, Biljana, D'Amato, Gennaro, da Silva, Jane, Dantas, Carina, Dokic, Dejan, Dauvilliers, Yves, De Feo, Giulia, De Vries, Govert, Devillier, Philippe, Di Capua, Stefania, Dray, Gerard, Dubakiene, Ruta, Durham, Stephen R., Dykewicz, Marc, Ebisawa, Motohiro, Gaga, Mina, El-Gamal, Yehia, Heffler, Enrico, Emuzyte, Regina, Farrell, John, Fauquert, Jean-Luc, Fiocchi, Alessandro, Fink-Wagner, Antje, Fontaine, Jean-Francois, Fuentes Perez, Jose M., Gemicioglu, Bilun, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gevaert, Philippe, Gomez, Rene Maximiliano, Gonzalez Diaz, Sandra, Gotua, Maia, Guldemond, Nick A., Guzman, Maria-Antonieta, Hajjam, Jawad, Huerta Villalobos, Yunuen R., Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Iinuma, Tomohisa, Jassem, Ewa, Joos, Guy, Jung, Ki-Suck, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Musa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kouznetsov, Rostislav, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, La Grutta, Stefania, Leonardini, Lisa, Ljungberg, Henrik, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Lopes-Pereira, Catarina, Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Mahboub, Bassam, Makris, Michael, Malva, Joao, Manning, Patrick, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Carreiro-Martins, Pedro, Makela, Mika, Mathieu-Dupas, Eve, Maurer, Marcus, De Manuel Keenoy, Esteban, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Mercier, Jacques, Micheli, Yann, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mitsias, Dimitirios I., Moda, Giuliana, Mogica-Martinez, Maria-Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mosges, Ralph, Munter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leyla, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Nordlund, Bjorn, Novellino, Ettore, Nyembue, Dieudonne, O'Hehir, Robyn, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle L., Orlando, Valentina, Ouedraogo, Solange, Palamarchuk, Julia, Pali-Scholl, Isabella, Panzner, Peter, Park, Hae-Sim, Passalacqua, Gianni, Pepin, Jean-Louis, Paulino, Ema, Pawankar, Ruby, Phillips, Jim, Picard, Robert, Pinnock, Hilary, Plavec, Davor, Popov, Todor A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Psarros, Fotis, Pugin, Benoit, Puggioni, Francesca, Quinones-Delgado, Pablo, Raciborski, Filip, Rajabian-Soderlund, Rojin, Regateiro, Frederico S., Reitsma, Sietze, Rivero-Yeverino, Daniela, Roberts, Graham, Roche, Nicolas, Rodriguez-Zagal, Erendira, Roller-Wirnsberger, Regina E., Rosario, Nelson, Romano, Antonino, Rottem, Menachem, Ryan, Dermot, Salimaki, Johanna, Sanchez-Borges, Mario M., Sastre, Joaquin, Scadding, Glenis K., Scheire, Sophie, Schmid-Grendelmeier, Peter, Schunemann, Holger J., Sarquis Serpa, Faradiba, Shamji, Mohamed, Sisul, Juan-Carlos, Sole, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spertini, Spranger, Otto, Stellato, Cristiana, Stelmach, Rafael, Thibaudon, Michel, To, Teresa, Toumi, Mondher, Usmani, Omar, Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, Pereira, Marilyn Urrutia, van der Kleij, Rianne, Van Eerd, Michiel, Vandenplas, Olivier, Vasankari, Tuula, Vaz Carneiro, Antonio, Vezzani, Giorgio, Viart, Frederic, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yusuf, Osman M., Zar, Heather J., Zeng, Stephane, Zernotti, Mario E., Zhang, Luo, Shan Zhong, Nan, and Zidarn, Mihaela
Abstract: Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed.
Published: 2021
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75. Communication during the COVID-19 pandemic: evaluation study on self-perceived competences and views of health care professionals

Author: Schlögl, Mathias; https://orcid.org/0000-0002-6299-8852, Singler, Katrin, Martinez-Velilla, Nicolas, Jan, Schildmann, Bischoff-Ferrari, Heike A; https://orcid.org/0000-0002-4554-658X, Roller-Wirnsberger, Regina Elisabeth, Attier-Zmudka, Jadwiga, Jones, Christopher A, Miot, Stéphanie, Gordon, Adam L, Schlögl, Mathias; https://orcid.org/0000-0002-6299-8852, Singler, Katrin, Martinez-Velilla, Nicolas, Jan, Schildmann, Bischoff-Ferrari, Heike A; https://orcid.org/0000-0002-4554-658X, Roller-Wirnsberger, Regina Elisabeth, Attier-Zmudka, Jadwiga, Jones, Christopher A, Miot, Stéphanie, and Gordon, Adam L
Abstract: PURPOSE The aims of this study were to describe communication experiences while wearing a mask during COVID-19 pandemic in 2020, to identify possible mask-related barriers to COVID-19-adapted communications and to investigate whether the ABC mnemonic (A: attend mindfully; B: behave calmly; C: communicate clearly) might address these. METHODS This study was a cross-sectional, voluntary, web-based survey between January and February 2021. A 22-item survey was developed using the Surveymonkey platform and question styles were varied to include single choice and Likert scales. The respondents were also asked to view a short video presentation, which outlined the ABC mnemonic. CHERRIES (Checklist for Reporting Results of Internet E-Surveys) was used to ensure completeness of reporting. Diverging stacked bar charts were created to illustrate Likert scale responses. RESULTS We received 226 responses. The respondents were mostly women (60.2%) and the majority worked in a teaching hospital (64.6%). The majority of the respondents indicated issues related to lack of time during clinical encounters, uncertainty about how to adapt communication, lack of personal protective equipment, lack of communication skills and lack of information about how to adapt their own communication skills. In addition, the participants indicated acknowledging emotions and providing information using clear, specific, unambiguous, and consistent lay language while wearing a mask were among the main communication challenges created during the COVID-19 pandemic. Finally, the study showed significantly improved self-perceived competency regarding key communication after watching the short video presentation. CONCLUSION Effective communication in medical encounters requires both verbal and nonverbal skills.
Published: 2021

76. Potentially inappropriate medication in geriatric patients: the Austrian consensus panel list

Author: Mann, Eva, Böhmdorfer, Birgit, Frühwald, Thomas, Roller-Wirnsberger, Regina E., Dovjak, Peter, Dückelmann-Hofer, Christine, Fischer, Peter, Rabady, Susanne, and Iglseder, Bernhard
Published: 2012
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77. Einstellungen zur altersbedingten Rationierung von Gesundheitsleistungen: Ergebnisse einer Analyse in Deutschland und Österreich

Author: Esslinger, Adelheid Susanne, Meier, Florian, Roller-Wirnsberger, Regina E., and Heppner, Hans Jürgen
Published: 2011
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78. Krank oder nur alt? Frailty – Ein neues Konzept in der Klinischen Praxis

Author: Roller-Wirnsberger, Regina
Published: 2010
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79. “One Health” Approach for Health Innovation and Active Aging in Campania (Italy)

Author: De Luca, Vincenzo, primary, Tramontano, Giovanni, additional, Riccio, Luigi, additional, Trama, Ugo, additional, Buono, Pietro, additional, Losasso, Mario, additional, Bracale, Umberto Marcello, additional, Annuzzi, Giovanni, additional, Zampetti, Rosa, additional, Cacciatore, Francesco, additional, Vallefuoco, Giannamaria, additional, Lombardi, Alberto, additional, Marro, Anna, additional, Melone, Mariarosa Anna Beatrice, additional, Ponsiglione, Cristina, additional, Chiusano, Maria Luisa, additional, Bracale, Giancarlo, additional, Cafiero, Gaetano, additional, Crudeli, Aurelio, additional, Vecchione, Carmine, additional, Taglialatela, Maurizio, additional, Tramontano, Donatella, additional, Iaccarino, Guido, additional, Triassi, Maria, additional, Roller-Wirnsberger, Regina, additional, Bousquet, Jean, additional, and Illario, Maddalena, additional
Published: 2021
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80. Transient versus stable nature of fear of falling over 24 months in community-older persons with falls- data of the EU SCOPE project on Kidney function.

Author: Freiberger, Ellen, Fabbietti, Paolo, Corsonello, Andrea, Lattanzio, Fabrizia, Artzi-Medvedik, Rada, Kob, Robert, Melzer, Itshak, SCOPE consortium, Wirnsberger, Gerhard, Roller-Wirnsberger, Regina, Mattace-Raso, Francesco, Tap, Lisanne, Kostka, Tomasz, Guligowska, Agnieszka, Formiga, Francesc, Moreno-González, Rafael, Gil, Pedro, Martínez, Sara Laínez, Bekmann, Andreas, and Weingart, Christian
Abstract: Background: Fear of falling (FoF) is an important risk factor for falls among older people. The objectives of our investigations were: a.) to present characteristics of older community-dwelling (CD) fallers with persistent or transient FoF (P-FoF or T-FoF) over 12 months, and b.) to investigate clinical predictors of P-FoF and T-FoF and c.) to explore differences between P-FoF and T-FoF.Methods: Our series consisted of 389 older people reporting a fall or injurious fall at baseline and during 24 months follow-up participating in a multicenter prospective study. T-FoF was defined as participants reported "not at all" at baseline and "somewhat/fairly/very concerned" at follow-up, or "not at all" at follow-up, and "somewhat/fairly/very concerned" at baseline, and P-FoF was defined as participants answered "somewhat/fairly/very concerned" in both assessments at baseline and at follow-up. The association between risk factors and T-FoF or P-FoF was investigated by logistic regression analysis.Results: The mean age of fallers in our sample was 79.0 years (SD 6.0), and 54.2% were females. Out of 389 older adults with a fall history at baseline, 83 participants (21.3%) did not report any FoF over time, P-FoF and T-FoF were observed in 42.7% and 35.9% of participants, respectively. After adjusting for potential confounders (e.g. age, gender), osteoporosis (OR = 2.04, 95%CI = 1.03-4.05) and impaired physical performance (OR = 2.38, 95%CI = 1.12-5.03) were significant predictors of T-FoF vs No-FoF. Osteoporosis (OR = 2.68, 95%CI = 1.31-5.48), depressive symptoms (OR = 3.54, 95%CI = 1.23-10.1) and living alone (OR = 2.44, 95%CI = 1.17-5.06) were significantly associated with P-FoF vs No-FoF. When comparing T-FoF and P-FoF, female gender (OR = 1.95, 95%CI = 1.16-3.27), BMI (OR = 1.08, 95%CI = 1.02-1.14), overall comorbidity (OR = 1.07, 95%CI = 1.02-1.13) and depression (OR = 2.55, 95%CI = 1.33-4.88) were significant predictors of P-FoF.Conclusions: T-FoF and P-FoF may be predicted by different sets of risk factors among older fallers. Thus, fallers should be screened for FoF especially when carrying specific risk factors, including female gender, osteoporosis, depression, living alone, impaired physical performance, BMI, comorbidity. These findings may be helpful in designing tailored intervention to blunt the risks related to consequence of FoF among older people experiencing falls.Trial Registration: The SCOPE study was registered prospectively at clinicaltrials.gov (NCT02691546; 25/02/2016). [ABSTRACT FROM AUTHOR]
Published: 2022
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81. relevance of geriatric assessments on the association between chronic kidney disease stages and mortality among older people: a secondary analysis of a multicentre cohort study.

Author: Corsonello, Andrea, Soraci, Luca, Ärnlöv, Johan, Carlsson, Axel C, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Mattace-Raso, Francesco, Tap, Lisanne, Formiga, Francesc, Moreno-González, Rafael, Kostka, Tomasz, Guligowska, Agnieszka, Artzi-Medvedik, Rada, Melzer, Itshak, Weingart, Christian, Sieber, Cornell, Lattanzio, Fabrizia, and investigators, the Screening for CKD among Older People across Europe (SCOPE) study
Subjects: KIDNEY physiology, CHRONIC kidney failure, RESEARCH, GLOMERULAR filtration rate, GRIP strength, COGNITION disorders, CONFIDENCE intervals, GERIATRIC assessment, ACTIVITIES of daily living, BODY movement, MALNUTRITION, SURVIVAL analysis (Biometry), DESCRIPTIVE statistics, SECONDARY analysis, LONGITUDINAL method, DEPENDENCY (Psychology), PROPORTIONAL hazards models, OLD age
Abstract: Background age-adapted definition of chronic kidney disease (CKD) does not take individual risk factors into account. We aimed at investigating whether functional impairments influence CKD stage at which mortality increases among older people. Methods our series consisted of 2,372 outpatients aged 75 years or more enrolled in a multicentre international prospective cohort study. The study outcome was 24-month mortality. Kidney function was assessed by estimated glomerular filtration rate (eGFR) and albumin-to-creatinine ratio (ACR). Geriatric assessments included handgrip strength, short physical performance battery (SPPB), cognitive impairment, dependency in basic activities of daily living (BADL) and risk of malnutrition. Analysis was carried out by Cox regression, before and after stratification by individual functional impairments. Survival trees including kidney function and functional impairments were also investigated, and their predictivity assessed by C-index. Results overall, mortality was found to increase starting from eGFR = 30–44.9 ml/min/1.73 m2 (hazard ratio [HR] = 3.28, 95% confidence interval [CI] = 1.81–5.95) to ACR = 30–300 mg/g (HR = 1.96, 95%CI = 1.23–3.10). However, in survival trees, an increased risk of mortality was observed among patients with impaired handgrip and eGFR = 45–59.9 ml/min/1.73 m2, as well as patients with ACR < 30 mg/g and impaired handgrip and SPPB. Survival tree leaf node membership had greater predictive accuracy (C-index = 0.81, 95%CI = 0.78–0.84 for the eGFR survival tree and C-index = 0.77, 95%CI = 0.71–0.81 for the ACR survival tree) in comparison with that of individual measures of kidney function. Conclusions physical performance helps to identify a proportion of patients at an increased risk of mortality despite a mild–moderate impairment in kidney function and improves predictive accuracy of individual measures of kidney function. [ABSTRACT FROM AUTHOR]
Published: 2022
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82. Palliative care competencies for geriatricians across Europe: a Delphi consensus study

Author: Pautex, Sophie, the SIG palliative care, SIG education of the European Geriatric Medicine Society (EuGMS), [missing], Roller-Wirnsberger, Regina, Singler, Katrin, and Van Den Noortgate, Nele
Subjects: medicine.medical_specialty, Geriatric medicine, Palliative care, Consensus, Delphi Technique, education, Likert scale, 03 medical and health sciences, 0302 clinical medicine, 030502 gerontology, Health care, Medicine and Health Sciences, medicine, media_common.cataloged_instance, Humans, 030212 general & internal medicine, European Union, European union, Curriculum, Competence (human resources), media_common, Aged, Geriatrics, Medical education, business.industry, Palliative Care, Postgraduate training, Geriatricians, Special Interest Group, ddc:618.97, Older people, 0305 other medical science, business, Research Paper
Abstract: Key summary points Aim to develop a set of specific palliative care competencies to be recommended for training at a postgraduate level of geriatricians across Europe. Findings A list of 35 palliative care competencies for geriatricians is now available for implementation in the different European countries. Message Future action are needed to support implementation and evaluation of the recommendations based upon key performance indicators within different health care systems., Purpose Integration of palliative care competencies with geriatric medicine is important for quality of care for older people, especially in the last years of their life. Therefore, knowledge and skills about palliative care for older people should be mandatory for geriatricians. The European Geriatric Medicine Society (EuGMS) has launched a postgraduate curriculum for geriatric medicine recently. Aim Based on this work, the Special Interest Group (SIG) on Palliative care in collaboration with the SIG in Education and Training aimed to develop a set of specific palliative care competencies to be recommended for training at a postgraduate level. Methods Competencies were defined using a modified Delphi technique based upon a Likert like rating scale. A template to kick off the first round and including 46 items was developed based on pre-existing competencies developed in Switzerland and Belgium. Results Three Delphi rounds were necessary to achieve full consensus. Experts came from 12 EU countries. In the first round, the wording of 13 competencies and the content of 10 competencies were modified. We deleted or merged ten competencies, mainly because they were not specific enough. At the end of the 2nd round, one competence was deleted and for three questions the wordings were modified. These modifications had the agreement of the participants during the last round. Conclusion A list of 35 palliative care competencies for geriatricians is now available for implementation in European countries.
Published: 2020

83. Chronic kidney disease in the context of multimorbidity patterns: the role of physical performance

Author: Corsonello, Andrea, Fabbietti, Paolo, Formiga Pérez, Francesc, Moreno González, Rafael, Tap, Lisanne, Mattace-Raso, Francesco, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Ärnlöv, Johan, Carlsson, Axel C., Weingart, Christian, Freiberger, Ellen, Kostka, Tomasz, Guligowska, Agnieszka, Gil, Pedro, Lainez Martinez, Sara, Melzer, Itshak, Yehoshua, Ilan, Lattanzio, Fabrizia, Corbella, Xavier, Martínez, Yurema, Polo, Carolina, Cruzado, Josep Ma., and SCOPE investigators
Subjects: Insuficiència renal crònica, Chronic renal failure, Older people, urologic and male genital diseases, female genital diseases and pregnancy complications, Persones grans
Abstract: Background: Chronic kidney disease (CKD) is known to be associated with several co-occurring conditions. We aimed at exploring multimorbidity patterns associated with CKD, as well as the impact of physical performance and CKD severity on them in a population of older outpatients. Methods: Our series consisted of 2252 patients enrolled in the Screening of CKD among Older People across Europe multicenter observational study. Hypertension, stroke, transient ischemic attack, cancer, hip fracture, osteoporosis, Parkinson's disease, asthma, chronic obstructive pulmonary disease, congestive heart failure, angina, myocardial infarction, atrial fibrillation, anemia, CKD (defined as GFR < 60
Published: 2020

84. Anwendung von biologika bei allergischen und Typ-2-entzündlichen Erkrankungen in der aktuellen COVID-19-Pandemie

Author: Klimek, Ludger, Pfaar, Dr O., Worm, Margitta M., Eiwegger, Thomas, Hagemann, Jan, Ollert, Markus W., Untersmayr, Eva, Hoffmann-Sommergruber, Karin, Vultaggio, Alessandra, Agache, Ioana O., Bavbek, S., Bossios, Apostolos, Casper, Ingrid, Chan, Susan, Chatzipetrou, A., Vogelberg, Christian, Firinu, Davide, Kauppi, P., Kolios, Antonios G.A., Kothari, Akash, Matucci, Andrea, Palomares, Óscar, Szépfalusi, Zsolt, Hötzenecker, Wolfram, Rosenkranz, A. R., Bergmann, Karl Christian, Bieber, Thomas, Buhl, Roland, Buters, Jeroen T.M., Darsow, Ulf G., Keil, Thomas, Kleine-Tebbe, Jörg, Lau, S., Maurer, Marcus, Merk, Hans Friedrich, Mösges, Ralph, Saloga, Joachim, Staubach, Petra, Jappe, Uta, Rabe, Klaus Friedrich, Rabe, Uta, Vogelmeier, Claus Franz, Biedermann, Tilo M., Jung, Kirsten, Schlenter, Wolfgang W., Ring, Johannnes, Chaker, Adam M., Wehrmann, Wolfgang, Becker, Sven, Freudelsperger, Laura, Mülleneisen, Norbert K., Nemat, Katja, Czech, Wolfgang, Wrede, Holger, Brehler, Randolph B.S., Fuchs, Thomas, Tomazic, Peter Valentin, Aberer, Werner, Fink-Wagner, Antjie Henriette, Horak, Friedrich, Wöhrl, Stefan, Niederberger-Leppin, Verena, Pali-Schöll, Isabella, Pohl, Wolfgang, Roller-Wirnsberger, Regina Elisabeth, Spranger, Otto, Valenta, Rudolf, Akdis, Mübeccel, Matricardi, Paolo Maria, Spertini, François, Khaltaev, Nikolaï G., Michel, Jean Pierre, Nicod, Laurent Pierre, Schmid-Grendelmeier, Peter D., Idzko, Marco, Hamelmann, E., Jakob, Thilo, Werfel, Thomas Andreas, Wagenmann, Martin M., Taube, Christian, Jensen-Jarolim, Erika, Korn, Stephanie, Hentges, François R., Schwarze, Jürgen, O'Mahony, Liam, Knol, Edward Frank, del Giacco, Stefano R., Chivato Pérez, T., Bousquet, Jean J., Zuberbier, Thorsten, Akdis, Cezmi A., Jutel, Marek, MACVIA-France, Montpellier, Centre de recherche en épidémiologie et santé des populations (CESP), and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)
Subjects: SARS-CoV-2, [SDV]Life Sciences [q-bio], Benralizumab, Omalizumab, Dupilumab, Reslizumab, Covid-19, ComputingMilieux_MISCELLANEOUS, Mepolizumab, Telemedicine
Abstract: International audience
Published: 2020
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85. Can Integrated Care Help in Meeting the Challenges Posed on Our Health Care Systems by COVID-19? Some Preliminary Lessons Learned from the European VIGOUR Project

Author: Lindner, Sonja, Kubitschke, Lutz, Lionis, Christos, Anastasaki, Marilena, Kirchmayer, Ursula, Giacomini, Simona, De Luca, Vincenzo, Iaccarino, Guido, Illario, Maddalena, Maddalena, Antonio, Maritati, Antonio, Conforti, Diego, Roba, Isabella, Musian, Daniele, Cano, Antonio, Granell, Monica, Carriazo, Ana M., Lama, Carmen M., Rodríguez, Susana, Guligowska, Agnieszka, Kostka, Tomasz, Konijnendijk, Annemieke, Vitullo, Maria, Garcia-Rudolph, Alejandro, Sánchez, Javier Solana, Maggio, Marcello, Liotta, Giuseppe, Tziraki, Chariklia, Roller-Wirnsberger, Regina, Universitat Autònoma de Barcelona, Biomedical Signals and Systems, Lindner, S., Kubitschke, L., Lionis, C., Anastasaki, M., Kirchmayer, U., Giacomini, S., De Luca, V., Iaccarino, G., Illario, M., Maddalena, A., Maritati, A., Conforti, D., Roba, I., Musian, D., Cano, A., Granell, M., Carriazo, A. M., Lama, C. M., Rodriguez, S., Guligowska, A., Kostka, T., Konijnendijk, A., Vitullo, M., Garcia-Rudolph, A., Sanchez, J. S., Maggio, M., Liotta, G., Tziraki, C., and Roller-Wirnsberger, R.
Subjects: Health (social science), Evidence-based practice, Sociology and Political Science, Coronavirus disease 2019 (COVID-19), 030231 tropical medicine, Context (language use), Pandemic management, 03 medical and health sciences, 0302 clinical medicine, Perspective Paper, Political science, Health care, Pandemic, pandemic management, media_common.cataloged_instance, 030212 general & internal medicine, Vulnerable patients, European union, integrated care, media_common, lcsh:R5-920, business.industry, Social care, Health Policy, Integrated care, COVID-19, vulnerable patients, Public relations, health care, social care, Work (electrical), Settore MED/42, lcsh:Medicine (General), business
Abstract: The COVID-19 pandemic puts health and care systems under pressure globally. This current paper highlights challenges arising in the care for older and vulnerable populations in this context and reflects upon possible perspectives for different systems making use of nested integrated care approaches adapted during the work of the EU-funded project VIGOUR ("Evidence based Guidance to Scale-up Integrated Care in Europe", funded by the European Union's Health Programme 2014-2020 under Grant Agreement Number 826640).
Published: 2020

86. Allergen immunotherapy in the current COVID-19 pandemic: A position paper of AeDA, ARIA, EAACI, DGAKI and GPA: Position paper of the German ARIA GroupA in cooperation with the Austrian ARIA GroupB, the Swiss ARIA GroupC, German Society for Applied Allergology (AEDA)D, German Society for Allergology and Clinical Immunology (DGAKI)E, Society for Pediatric Allergology (GPA)F in cooperation with AG Clinical Immunology, Allergology and Environmental Medicine of the DGHNO-KHCG and the European Academy of Allergy and Clinical Immunology (EAACI)H

Author: Klimek, Ludger, Pfaar, Oliver, Worm, Margitta, Bergmann, Karl-Christian, Bieber, Thomas, Buhl, Roland, Buters, Jeroen, Darsow, Ulf, Keil, Thomas, Kleine-Tebbe, Jörg, Lau, Susanne, Maurer, Marcus, Merk, Hans, Mösges, Ralph, Saloga, Joachim, Staubach, Petra, Stute, Petra, Rabe, Klaus, Rabe, Uta, Vogelmeier, Claus, Biedermann, Tilo, Jung, Kirsten, Schlenter, Wolfgang, Ring, Johannes, Chaker, Adam, Wehrmann, Wolfgang, Becker, Sven, Mülleneisen, Norbert, Nemat, Katja, Czech, Wofgang, Wrede, Holger, Brehler, Randolf, Fuchs, Thomas, Tomazic, Peter-Valentin, Aberer, Werner, Fink-Wagner, Antje, Horak, Friedrich, Wöhrl, Stefan, Niederberger-Leppin, Verena, Pali-Schöll, Isabella, Pohl, Wolfgang, Roller-Wirnsberger, Regina, Spranger, Otto, Valenta, Rudolf, Akdis, Mübecell, Akdis, Cezmi, Hoffmann-Sommergruber, Karin, Jutel, Marek, Matricardi, Paolo, Spertin, FranÇois, Khaltaev, Nikolai, Michel, Jean-Pierre, Nicod, Laurent, Schmid-Grendelmeier, Peter, Hamelmann, Eckard, Jakob, Thilo, Werfel, Thomas, Wagenmann, Martin, Taube, Christian, Gerstlauer, Michael, Vogelberg, Christian, Bousquet, Jean, and Zuberbier, Torsten
Subjects: 610 Medicine & health
Abstract: No abstract available.
Published: 2020
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87. Allergen immunotherapy in the current COVID-19 pandemic - A position paper of the AeDA, ARIA, EAACI, DGAKI and GPA

Author: Klimek, Ludger, Pfaar, Dr O., Worm, Margitta M., Bergmann, Karl Christian, Bieber, Thomas, Buhl, Roland, Buters, Jeroen T.M., Darsow, Ulf G., Keil, Thomas, Kleine-Tebbe, Jörg, Lau, Susanne, Maurer, Mar, Merk, Hans Friedrich, Mösges, Ralph, Saloga, Joachim, Staubach, Petra, Stute, P., Rabe, Klaus, Rabe, Uta, Vogelmeier, Claus Franz, Biedermann, Tilo M., Jung, Kirsten, Schlenter, Wolfgang W., Ring, Johannnes, Chaker, Adam M., Wehrmann, Wolfgang, Becker, Sven, Mülleneisen, Norbert K., Nemat, Katja, Czech, Wolfgang, Wrede, Holger, Brehler, Randolph B.S., Fuchs, Thomas, Tomazic, Peter Valentin, Aberer, Werner, Fink-Wagner, Antjie Henriette, Horak, Friedrich, Wöhrl, Stefan, Niederberger-Leppin, Verena, Pali-Schöll, Isabella, Pohl, Wolfgang, Roller-Wirnsberger, Regina Elisabeth, Spranger, Otto, Valenta, Rudolf, Akdis, Mübeccel, Akdis, Cezmi A., Hoffmann-Sommergruber, Karin, Jutel, Marek, Matricardi, Paolo Maria, Spertini, François, Khaltaev, Nikolaï G., Michel, Jean Pierre, Nicod, Laurent, Schmid-Grendelmeier, Peter D., Hamelmann, E., Jakob, Thilo, Werfel, Thomas Andreas, Wagenmann, Martin, Taube, Christian, Gerstlauer, Michael, Vogelberg, Christian, Bousquet, Jean J., Zuberbier, Torsten, Rheinische Friedrich-Wilhelms-Universität Bonn, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA), and Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Subjects: SLIT, [SDV]Life Sciences [q-bio], COVID-19, Antiviral immunity, SCIT, ComputingMilieux_MISCELLANEOUS, Allergen immunotherapy
Abstract: International audience
Published: 2020
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88. Association between kidney function, nutritional status and anthropometric measures in older people

Author: Guligowska, Agnieszka, Corsonello, Andrea, Pigłowska, Małgorzata, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Ärnlöv, Johan, Carlsson, Axel C., Tap, Lisanne, Mattace-Raso, Francesco, Formiga, Francesc, Moreno-Gonzalez, Rafael, Freiberger, Ellen, Sieber, Cornel, Gregorio, Pedro Gil, Martínez, Sara Laínez, Artzi-Medvedik, Rada, Yehoshua, Ilan, Fabbietti, Paolo, Lattanzio, Fabrizia, and Kostka, Tomasz
Subjects: Aged, 80 and over, Male, Aging, Research, Malnutrition, Nutritional Status, Undernutrition, Overweight, Kidney, Body Mass Index, Berlin, Europe, Cross-Sectional Studies, MNA, Chronic kidney disease, Humans, Female, Obesity, ddc:610, Israel, Aged
Abstract: Background Different mechanisms connect the nutritional status with the occurrence and the course of chronic kidney disease (CKD). The end-stage renal disease is complicated by catabolic inflammatory reactions and cachexia which leads to malnutrition (undernutrition). On the other hand, obesity is an important risk factor for the development and acceleration of CKD. Methods In the SCOPE study, community-dwelling persons aged 75 years and over, from 6 European countries and Israel were examined at the baseline phase. We assessed the relationship between anthropometric measures (Body Mass Index (BMI), circumferences of arm (AC), waist (WC), hip (HC), and calf (CC), waist-to-hip ratio - WHR, waist-to-height ratio - WHtR, risk of malnutrition (Mini Nutritional Assessment - MNA), serum albumin) and estimated glomerular filtration rate (eGFR) calculated by Berlin Initiative Study (BIS) equation. Results We studied 2151 subjects (932 men and 1219 women) with a mean age of 79.5 ± 5.9 years. A total of 1333 (62%) participants had CKD (GRF 60 (OR = 2.95, 95%CI = 1.77–4.94 for MNA
Published: 2020

89. Rethinking palliative care in a public health context: addressing the needs of persons with non-communicable chronic diseases - CORRIGENDUM

Author: Tziraki, Chariklia, Grimes, Corrina, Ventura, Filipa, O'Caoimh, Ronan, Santana, Silvina, Zavagli, Veronica, Varani, Silvia, Tramontano, Donatella, Apóstolo, João, Geurden, Bart, Luca, Vincenzo de, Tramontano, Giovanni, Romano, Maria Rosaria, Anastasaki, Marilena, Lionis, Christos, Rodríguez-Acuña, Rafael, Capelas, Manuel Luís, Afonso, Tânia dos Santos, Molloy, D. William, Liotta, Giuseppe, Iaccarino, Guido, Triassi, Maria, Eklund, Patrik, Roller-Wirnsberger, Regina, Illario, Maddalena, Tziraki, C., Grimes, C., Ventura, F., O'Caoimh, R., Santana, S., Zavagli, V., Varani, S., Tramontano, D., Apostolo, J., Geurden, B., De Luca, V., Tramontano, G., Rosaria Romano, M., Anastasaki, M., Lionis, C., Rodriguez-Acuna, R., Capelas, M. L., Dos Santos Afonso, T., William Molloy, D., Liotta, G., Iaccarino, G., Triassi, M., Eklund, P., Roller-Wirnsberger, R., Illario, M., and Veritati - Repositório Institucional da Universidade Católica Portuguesa
Subjects: palliative care, multimorbidity, public health, Public Health, Environmental and Occupational Health, Development, integrated, non-communicable chronic diseases (NCCDs), Care Planning
Abstract: Non-communicable chronic diseases (NCCDs) are the main cause of morbidity and mortality globally. Demographic aging has resulted in older populations with more complex healthcare needs. This necessitates a multilevel rethinking of healthcare policies, health education and community support systems with digitalization of technologies playing a central role. The European Innovation Partnership on Active and Healthy Aging (A3) working group focuses on well-being for older adults, with an emphasis on quality of life and healthy aging. A subgroup of A3, including multidisciplinary stakeholders in health care across Europe, focuses on the palliative care (PC) model as a paradigm to be modified to meet the needs of older persons with NCCDs. This development paper delineates the key parameters we identified as critical in creating a public health model of PC directed to the needs of persons with NCCDs. This paradigm shift should affect horizontal components of public health models. Furthermore, our model includes vertical components often neglected, such as nutrition, resilience, well-being and leisure activities. The main enablers identified are information and communication technologies, education and training programs, communities of compassion, twinning activities, promoting research and increasing awareness amongst policymakers. We also identified key ‘bottlenecks’: inequity of access, insufficient research, inadequate development of advance care planning and a lack of co-creation of relevant technologies and shared decision-making. Rethinking PC within a public health context must focus on developing policies, training and technologies to enhance person-centered quality life for those with NCCD, while ensuring that they and those important to them experience death with dignity.
Published: 2020

90. Handling of allergen immunotherapy in the COVID-19 pandemic: An ARIA-EAACI-AeDA-GPA-DGAKI Position Paper (Pocket-Guide)

Author: Pfaar, Oliver, Klimek, Ludger, Worm, Margitta M., Bergmann, Karl Christian, Bieber, Thomas, Buhl, Roland, Buters, Jeroen T.M., Darsow, Ulf G., Keil, T., Kleine-Tebbe, Jörg, Lau, S., Maurer, Marcus, Merk, Hans Friedrich, Mösges, Ralph, Saloga, Joachim, Staubach, Petra, Stute, P., Rabe, K., Rabe, Uta, Vogelmeier, Claus Franz, Biedermann, Tilo M., Jung, K., Schlenter, Wolfgang W., Ring, J., Chaker, Adam M., Wehrmann, Wolfgang, Becker, Sven, Mülleneisen, Norbert K., Nemat, Katja, Czech, Wolfgang, Wrede, Holger, Brehler, Randolph B.S., Fuchs, Thomas, Tomazic, Peter Valentin, Aberer, Werner, Fink-Wagner, Antjie Henriette, Horak, Friedrich, Wöhrl, Stefan, Niederberger-Leppin, Verena, Pali-Schöll, Isabella, Pohl, Wolfgang, Roller-Wirnsberger, Regina Elisabeth, Spranger, Otto, Valenta, Rudolf, Akdis, Mübeccel, Akdis, Cezmi A., Hoffmann-Sommergruber, Karin, Jutel, Marek, Matricardi, Paolo Maria, Spertini, François, Khaltaev, Nikolaï G., Michel, Jean Pierre, Nicod, Laurent Pierre, Schmid-Grendelmeier, Peter D., Hamelmann, E., Jakob, Thilo, Werfel, Thomas Andreas, Wagenmann, Martin M., Taube, C., Gerstlauer, Michael, Vogelberg, Christian, Bousquet, Jean J., Zuberbier, Thorsten, Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), FMC VIA LR, 371, avenue Doyen-Gaston-Giraud, 34295 Montpellier cedex 5, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), and Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO)
Subjects: [SHS.LANGUE]Humanities and Social Sciences/Linguistics, ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2020
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91. Use of biologicals in allergic and type-2 inflammatory diseases during the current COVID-19 pandemic:Position paper of Ärzteverband Deutscher Allergologen (AeDA)A, Deutsche Gesellschaft für Allergologie und Klinische Immunologie (DGAKI)B, Gesellschaft für Pädiatrische Allergologie und Umweltmedizin (GPA)C, Österreichische Gesellschaft für Allergologie und Immunologie (ÖGAI)D, Luxemburgische Gesellschaft für Allergologie und Immunologie (LGAI)E, Österreichische Gesellschaft für Pneumologie (ÖGP)F in co-operation with the German, Austrian, and Swiss ARIA groupsG, and the European Academy of Allergy and Clinical Immunology (EAACI)

Author: Klimek, Ludger, Pfaar, Oliver, Worm, Margitta, Eiwegger, Thomas, Hagemann, Jan, Ollert, Markus, Untersmayr, Eva, Hoffmann-Sommergruber, Karin, Vultaggio, Alessandra, Agache, Ioana, Bavbek, Sevim, Bossios, Apostolos, Casper, Ingrid, Chan, Susan, Chatzipetrou, Alexia, Vogelberg, Christian, Firinu, Davide, Kauppi, Paula, Kolios, Antonios, Kothari, Akash, Matucci, Andrea, Palomares, Oscar, Szépfalusi, Zsolt, Pohl, Wolfgang, Hötzenecker, Wolfram, Rosenkranz, Alexander, Bergmann, Karl-Christian, Bieber, Thomas, Buhl, Roland, Buters, Jeroen, Darsow, Ulf, Keil, Thomas, Kleine-Tebbe, Jörg, Lau, Susanne, Maurer, Marcus, Merk, Hans, Mösges, Ralph, Saloga, Joachim, Staubach, Petra, Jappe, Uta, Rabe, Klaus, Rabe, Uta, Vogelmeier, Claus, Biedermann, Tilo, Jung, Kirsten, Schlenter, Wolfgang, Ring, Johannes, Chaker, Adam, Wehrmann, Wolfgang, Becker, Sven, Freudelsperger, Laura, Mülleneisen, Norbert, Nemat, Katja, Czech, Wolfgang, Wrede, Holger, Brehler, Randolf, Fuchs, Thomas, Tomazic, Peter-Valentin, Aberer, Werner, Fink-Wagner, Antje-Henriette, Horak, Fritz, Wöhrl, Stefan, Niederberger-Leppin, Verena, Pali-Schöll, Isabella, Roller-Wirnsberger, Regina, Spranger, Otto, Valenta, Rudolf, Akdis, Mübecell, Matricardi, Paolo, Spertini, François, Khaltaev, Nicolai, Michel, Jean-Pierre, Nicod, Larent, Schmid-Grendelmeier, Peter, Idzko, Marco, Hamelmann, Eckard, Jakob, Thilo, Werfel, Thomas, Wagenmann, Martin, Taube, Christian, Jensen-Jarolim, Erika, Korn, Stephanie, Hentges, Francois, Schwarze, Jürgen, O Mahony, Liam, Knol, Edward, Del Giacco, Stefano, Chivato Pérez, Tomás, Bousquet, Jean, Bedbrook, Anna, Zuberbier, Torsten, Akdis, Cezmi, Jutel, Marek, Zentrum für Rhinologie und Allergologie [Wiesbaden, Germany], Philipps Universität Marburg, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], The Hospital for sick children [Toronto] (SickKids), University of Toronto, Johannes Gutenberg - Universität Mainz (JGU), Luxembourg Institute of Health (LIH), University of Southern Denmark (SDU), Medizinische Universität Wien = Medical University of Vienna, Careggi University Hospital [Florence, Italie], Transylvania University, Ankara University School of Medicine [Turkey], Karolinska University Hospital [Stockholm], Karolinska Institutet [Stockholm], University hospital of Zurich [Zurich], Universität Zürich [Zürich] = University of Zurich (UZH), Guy's and St Thomas' Hospital [London], King‘s College London, National Technical University of Athens [Athens] (NTUA), University General Hospital ' Attikon ' [Athens, Greece], University of Athens Medical School [Athens], Universitätsklinikum Carl Gustav Carus Dresden, University of Cagliari, Harvard Medical School [Boston] (HMS), Österreichische Forschungsförderungsgesellschaft, Universidad Complutense de Madrid = Complutense University of Madrid [Madrid] (UCM), Kepler University Hospital, Medizinische Universität Graz, Universitätsklinikum Bonn (UKB), Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Helmholtz-Zentrum München (HZM), Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), University of Würzburg = Universität Würzburg, Allergie- & Asthma-Zentrum Berlin Westend, Universitätsklinikum RWTH Aachen - University Hospital Aachen [Aachen, Germany] (UKA), RWTH Aachen University, Universität zu Köln, Clinical Research International Ltd [Hamburg, Germany] (CRI), University Medical Center [Mainz], Universität zu Lübeck [Lübeck], German Research Center for Environmental Health - Helmholtz Center München (GmbH), Universitätsklinikum Tübingen - University Hospital of Tübingen, Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen, Asthma und Allergiezentrum [Leverkusen], Universitätsklinikum Münster [Munster, Germany], University of Göttingen - Georg-August-Universität Göttingen, Universität Wien, Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA), Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV), University of Geneva [Switzerland], Universitätsspital Zürich (USZ), Universität Bielefeld = Bielefeld University, Justus-Liebig-Universität Gießen (JLU), Medizinische Hochschule Hannover (MHH), Universitatsklinikum Dusseldorf, Dusseldorf Germany, Universitätsklinikum Essen [Universität Duisburg-Essen] (Uniklinik Essen), Centre Hospitalier de Luxembourg [Luxembourg] (CHL), University of Edinburgh, APC Microbiome Ireland, University College Cork (UCC), University Medical Center [Utrecht], Universita degli Studi di Cagliari [Cagliari], University of San Pablo, Humboldt-Universität zu Berlin, Wroclaw Medical University [Wrocław, Pologne], and Technische Universität München [München] (TUM)
Subjects: benralizumab, SARS-CoV-2, COVID-19, mepolizumab, Benralizumab, Omalizumab, Dupilumab, reslizumab, Telemedicine, dupilumab, omalizumab, telemedicine, Reslizumab, Covid-19, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Mepolizumab
Abstract: International audience; Background: Since the beginning of the COVID-19 pandemic, the treatment of patients with allergic and atopy-associated diseases has faced major challenges. Recommendations for "social distancing" and the fear of patients becoming infected during a visit to a medical facility have led to a drastic decrease in personal doctor-patient contacts. This affects both acute care and treatment of the chronically ill. The immune response after SARS-CoV-2 infection is so far only insufficiently understood and could be altered in a favorable or unfavorable way by therapy with monoclonal antibodies. There is currently no evidence for an increased risk of a severe COVID-19 course in allergic patients. Many patients are under ongoing therapy with biologicals that inhibit type 2 immune responses via various mechanisms. There is uncertainty about possible immunological interactions and potential risks of these biologicals in the case of an infection with SARS-CoV-2.Materials and methods: A selective literature search was carried out in PubMed, Livivo, and the internet to cover the past 10 years (May 2010 - April 2020). Additionally, the current German-language publications were analyzed. Based on these data, the present position paper provides recommendations for the biological treatment of patients with allergic and atopy-associated diseases during the COVID-19 pandemic.Results: In order to maintain in-office consultation services, a safe treatment environment must be created that is adapted to the pandemic situation. To date, there is a lack of reliable study data on the care for patients with complex respiratory, atopic, and allergic diseases in times of an imminent infection risk from SARS-CoV-2. Type-2-dominant immune reactions, as they are frequently seen in allergic patients, could influence various phases of COVID-19, e.g., by slowing down the immune reactions. Theoretically, this could have an unfavorable effect in the early phase of a SARS-Cov-2 infection, but also a positive effect during a cytokine storm in the later phase of severe courses. However, since there is currently no evidence for this, all data from patients treated with a biological directed against type 2 immune reactions who develop COVID-19 should be collected in registries, and their disease courses documented in order to be able to provide experience-based instructions in the future.Conclusion: The use of biologicals for the treatment of bronchial asthma, atopic dermatitis, chronic rhinosinusitis with nasal polyps, and spontaneous urticaria should be continued as usual in patients without suspected infection or proven SARS-CoV-2 infection. If available, it is recommended to prefer a formulation for self-application and to offer telemedical monitoring. Treatment should aim at the best possible control of difficult-to-control allergic and atopic diseases using adequate rescue and add-on therapy and should avoid the need for systemic glucocorticosteroids. If SARS-CoV-2 infection is proven or reasonably suspected, the therapy should be determined by weighing the benefits and risks individually for the patient in question, and the patient should be involved in the decision-making. It should be kept in mind that the potential effects of biologicals on the immune response in COVID-19 are currently not known. Telemedical offers are particularly desirable for the acute consultation needs of suitable patients.
Published: 2020
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92. Prevalence of sarcopenia in community-dwelling older adults using the updated EWGSOP2 definition according to kidney function and albuminuria The Screening for CKD among Older People across Europe (SCOPE) study

Author: Moreno-Gonzalez, Rafael, Corbella, Xavier, Mattace-Raso, Francesco, Tap, Lisanne, Sieber, Cornel, Freiberger, Ellen, Kostka, Tomasz, Guligowska, Agnieszka, Melzer, Itshak, Melzer, Yehudit, Carlsson, Axel C, Ärnlöv, Johan, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Gil, Pedro, Martinez, Sara Lainez, Fabbietti, Paolo, Corsonello, Andrea, Lattanzio, Fabrizia, Formiga, Francesc, Moreno-Gonzalez, Rafael, Corbella, Xavier, Mattace-Raso, Francesco, Tap, Lisanne, Sieber, Cornel, Freiberger, Ellen, Kostka, Tomasz, Guligowska, Agnieszka, Melzer, Itshak, Melzer, Yehudit, Carlsson, Axel C, Ärnlöv, Johan, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Gil, Pedro, Martinez, Sara Lainez, Fabbietti, Paolo, Corsonello, Andrea, Lattanzio, Fabrizia, and Formiga, Francesc
Abstract: Background Loss of muscle mass and function may be more pronounced in older adults with chronic kidney disease (CKD) and with albuminuria. Thus, we investigated the prevalence of sarcopenia among community-dwelling older adults according to kidney function and grade of albuminuria. We also explored differences in the prevalence of sarcopenia according to three different equations for the estimation of glomerular filtration rate (eGFR). Methods A cross-sectional analysis of 1420 community-dwelling older adults (>= 75 years old) included in the SCOPE study, a multicenter prospective cohort study, was conducted. Comprehensive geriatric assessment including short physical performance battery (SPPB), handgrip strength test and bioelectrical impedance analysis (BIA) was performed. Sarcopenia was defined using the updated criteria of the European Working Group on Sarcopenia in Older People (EWGSOP2). eGFR was calculated using Berlin Initiative Study (BIS), Chronic Kidney Disease Epidemiological Collaboration (CKD-EPI) and Full Age Spectrum (FAS) equations, and urinary albumin-to-creatinine ratio (ACR) was collected to categorize CKD according to Kidney Disease Improving Global Outcomes guidelines. Results Median age was 79.5 years (77.0-83.0), 804 (56.6%) were women. Using EWGSOP2 definition, 150 (10.6%) participants met diagnostic criteria for sarcopenia. Moreover, 85 (6%) participants had severe sarcopenia. Sarcopenia was more prevalent in participants with more advanced stages of CKD according to BIS eq. (9.6% in stages 1 and 2 and 13.9% in stages 3a, 3b and 4,p = 0.042), and also according to CKD-EPI (9.8% vs. 14.2%, p = 0.042) and FAS although not reaching statistical signification (9.8% vs. 12.7%,p = 0.119). Thus, differences in prevalence are observed among CKD categories as estimated by different equations. Prevalence of sarcopenia was also higher with increasing albuminuria categories: 9.3% in normoalbuminuric, 13.2% in microalbuminuric and 16.8% in macroalbumi
Published: 2020
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93. Impaired kidney function is associated with lower quality of life among community-dwelling older adults The screening for CKD among older people across Europe (SCOPE) study

Author: Artzi-Medvedik, Rada, Kob, Robert, Fabbietti, Paolo, Lattanzio, Fabrizia, Corsonello, Andrea, Melzer, Yehudit, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Mattace-Raso, Francesco, Tap, Lisanne, Gil, Pedro, Martinez, Sara Lainez, Formiga, Francesc, Moreno-Gonzalez, Rafael, Kostka, Tomasz, Guligowska, Agnieszka, Ärnlöv, Johan, Carlsson, Axel C, Freiberger, Ellen, Melzer, Itshak, Artzi-Medvedik, Rada, Kob, Robert, Fabbietti, Paolo, Lattanzio, Fabrizia, Corsonello, Andrea, Melzer, Yehudit, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Mattace-Raso, Francesco, Tap, Lisanne, Gil, Pedro, Martinez, Sara Lainez, Formiga, Francesc, Moreno-Gonzalez, Rafael, Kostka, Tomasz, Guligowska, Agnieszka, Ärnlöv, Johan, Carlsson, Axel C, Freiberger, Ellen, and Melzer, Itshak
Abstract: Background Quality of life (QoL) refers to the physical, psychological, social and medical aspects of life that are influenced by health status and function. The purpose of this study was to measure the self-perceived health status among the elderly population across Europe in different stages of Chronic Kidney Disease (CKD). Methods Our series consisted of 2255 community-dwelling older adults enrolled in the Screening for Chronic Kidney Disease (CKD) among Older People across Europe (SCOPE) study. All patients underwent a comprehensive geriatric assessment (CGA), including included demographics, clinical and physical assessment, number of medications taken, family arrangement, Geriatric Depression Scale (GDS), Cumulative Illness Rating Scale, History of falls, Lower urinary tract symptoms, and Short Physical Performance Battery (SPPB). Estimated glomerular filtration rate (eGFR) was calculated by Berlin Initiative Study (BIS) equation. Quality of life was assessed by Euro Qol questionnaire (Euro-Qol 5D) and EQ-Visual Analogue Scale (EQ-VAS). The association between CKD (eGFR < 60, < 45 ml or < 30 ml/min/1.73m(2)) and low EQoL-VAS was investigated by multivariable logistic regression models. Results CKD was found to be significantly associated with low EQoL-VAS in crude analysis (OR = 1.47, 95%CI = 1.16-1.85 for eGFR< 60; OR = 1.38, 95%CI = 1.08-1.77 for eGFR< 45; OR = 1.57, 95%CI = 1.01-2.44). Such association was no longer significant only when adjusting for SPPB (OR = 1.20, 95%CI = 0.93-1.56 for eGFR< 60; OR = 0.87, 95%CI = 0.64-1.18 for eGFR< 45; OR = 0.84, 95%CI = 0.50-1.42), CIRS and polypharmacy (OR = 1.16, 95%CI = 0.90-1.50 for eGFR< 60; OR = 0.86, 95%CI = 0.64-1.16 for eGFR< 45; OR = 1.11, 95%CI = 0.69-1.80) or diabetes, hypertension and chronic obstructive pulmonary disease (OR = 1.28, 95%CI = 0.99-1.64 for eGFR< 60; OR = 1.16, 95%CI = 0.88-1.52 for eGFR< 45; OR = 1.47, 95%CI = 0.92-2.34). The association between CKD and lo
Published: 2020
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94. Is kidney function associated with cognition and mood in late life? : The Screening for CKD among Older People across Europe (SCOPE) study

Author: Tap, Lisanne, Corsonello, Andrea, Formiga, Francesc, Moreno-Gonzalez, Rafael, Ärnlöv, Johan, Carlsson, Axel C, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Ziere, Gijsbertus, Freiberger, Ellen, Sieber, Cornel, Kostka, Tomasz, Guligowska, Agnieszka, Gil, Pedro, Martinez, Sara Lainez, Artzi-Medvedik, Rada, Yehoshua, Ilan, Fabbietti, Paolo, Lattanzio, Fabrizia, Mattace-Raso, Francesco, Tap, Lisanne, Corsonello, Andrea, Formiga, Francesc, Moreno-Gonzalez, Rafael, Ärnlöv, Johan, Carlsson, Axel C, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Ziere, Gijsbertus, Freiberger, Ellen, Sieber, Cornel, Kostka, Tomasz, Guligowska, Agnieszka, Gil, Pedro, Martinez, Sara Lainez, Artzi-Medvedik, Rada, Yehoshua, Ilan, Fabbietti, Paolo, Lattanzio, Fabrizia, and Mattace-Raso, Francesco
Abstract: Background: Chronic kidney disease (CKD), cognitive impairment and depression share common risk factors. Previous studies did not investigate the possible association between kidney function and cognitive and mood disorders in older persons in a broad range of kidney function. The present study explored associations between kidney function, cognition and mood in outpatients of 75 years and over. Methods: Baseline data of 2252 participants of the SCOPE study, an international multicenter cohort observational study,were used in which community-dwelling persons of 75 years and over were enrolled to screen for CKD Kidney function was estimated with the BIS1-eGFR equation, cognition was assessed with the Mini-Mental State Examination (MMSE) and mood with the Geriatric Depression Scale 15 items (GDS-15). Characteristics were compared across stages of CKD. Mean eGFR values were also compared across categories of MMSE (< 24, 24-26, >= 27) and between groups with high and low score on the GDS-15 (> 5/<= 5). Results: In total, 63% of the population had an eGFR < 60 mL/min. In advanced stages of CKD, participants were older and more often men than in earlier stages (p < 0.001). Cardiovascular diseases and diabetes mellitus were more often found in those in advanced stages of CKD (p < 0.001), and also cumulative comorbidity scores were higher than in those in earlier stages (p < 0.001). Median MMSE was 29 in CKD stage 1-2 and 3, and 30 in CKD stage 4, whereas median GDS-15 score was 2 in all stages of CKD. Mean values of eGFR did not differ across categories of MMSE or between groups with high and low score on the GDS-15. Stratification for albuminuria did not change these results. Conclusions: Older persons in more advanced stages of CKD did not have lower cognitive scores or higher rates of depressive symptoms than older persons in earlier stages. Future longitudinal studies might give information on the possible effect of kidney function on cognition
Published: 2020
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95. Association between kidney function, nutritional status and anthropometric measures in older people The Screening for CKD among Older People across Europe (SCOPE) study

Author: Guligowska, Agnieszka, Corsonello, Andrea, Piglowska, Malgorzata, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Ärnlöv, Johan, Carlsson, Axel C, Tap, Lisanne, Mattace-Raso, Francesco, Formiga, Francesc, Moreno-Gonzalez, Rafael, Freiberger, Ellen, Sieber, Cornel, Gregorio, Pedro Gil, Martinez, Sara Lainez, Artzi-Medvedik, Rada, Yehoshua, Ilan, Fabbietti, Paolo, Lattanzio, Fabrizia, Kostka, Tomasz, Guligowska, Agnieszka, Corsonello, Andrea, Piglowska, Malgorzata, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Ärnlöv, Johan, Carlsson, Axel C, Tap, Lisanne, Mattace-Raso, Francesco, Formiga, Francesc, Moreno-Gonzalez, Rafael, Freiberger, Ellen, Sieber, Cornel, Gregorio, Pedro Gil, Martinez, Sara Lainez, Artzi-Medvedik, Rada, Yehoshua, Ilan, Fabbietti, Paolo, Lattanzio, Fabrizia, and Kostka, Tomasz
Abstract: Background Different mechanisms connect the nutritional status with the occurrence and the course of chronic kidney disease (CKD). The end-stage renal disease is complicated by catabolic inflammatory reactions and cachexia which leads to malnutrition (undernutrition). On the other hand, obesity is an important risk factor for the development and acceleration of CKD. Methods In the SCOPE study, community-dwelling persons aged 75 years and over, from 6 European countries and Israel were examined at the baseline phase. We assessed the relationship between anthropometric measures (Body Mass Index (BMI), circumferences of arm (AC), waist (WC), hip (HC), and calf (CC), waist-to-hip ratio - WHR, waist-to-height ratio - WHtR, risk of malnutrition (Mini Nutritional Assessment - MNA), serum albumin) and estimated glomerular filtration rate (eGFR) calculated by Berlin Initiative Study (BIS) equation. Results We studied 2151 subjects (932 men and 1219 women) with a mean age of 79.5 +/- 5.9 years. A total of 1333 (62%) participants had CKD (GRF < 60 ml/min/1.73 m(2)). Negative correlations between eGFR and weight, AC, WC, HC, CC, BMI, WHtR were observed. Positive correlation occurred between eGFR and MNA score (Spearman's rho = 0.11) and albumin concentration (rho = 0.09). Higher weight, AC, WC, HC, CC, BMI and WHtR increased the odds ratio of CKD; higher MNA (OR = 0.98, 95% CI 0.94-1.0) and higher serum albumin (OR = 0.73, 95% CI 0.53-1.0) were weakly associated with reduced odds. The risk of malnutrition was the highest with eGFR < 30 as compared to eGFR > 60 (OR = 2.95, 95%CI = 1.77-4.94 for MNA < 24; OR = 5.54, 95%CI = 1.66-18.5 for hypoalbuminemia < 3.5 g/dL). Conclusion The population of community dwelling people aged 75+ with CKD shows general features of overweight and obesity with a small prevalence of malnutrition. For anthropometric measures, the strongest association with eGFR and the highest odds of CKD were identified using WC, HC, CC and WHtR. Album
Published: 2020
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96. Kidney function and other factors and their association with falls updates The screening for CKD among older people across Europe (SCOPE) study

Author: Britting, Sabine, Artzi-Medvedik, Rada, Fabbietti, Paolo, Tap, Lisanne, Mattace-Raso, Francesco, Corsonello, Andrea, Lattanzio, Fabrizia, Ärnlöv, Johan, Carlsson, Axel C, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Kostka, Tomasz, Guligowska, Agnieszka, Formiga, Francesc, Moreno-Gonzalez, Rafael, Gil, Pedro, Martinez, Sara Lainez, Kob, Robert, Melzer, Itshak, Freiberger, Ellen, Britting, Sabine, Artzi-Medvedik, Rada, Fabbietti, Paolo, Tap, Lisanne, Mattace-Raso, Francesco, Corsonello, Andrea, Lattanzio, Fabrizia, Ärnlöv, Johan, Carlsson, Axel C, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Kostka, Tomasz, Guligowska, Agnieszka, Formiga, Francesc, Moreno-Gonzalez, Rafael, Gil, Pedro, Martinez, Sara Lainez, Kob, Robert, Melzer, Itshak, and Freiberger, Ellen
Abstract: Background: Reduced kidney function has become a major public health concern, especially among older people, as Chronic Kidney Disease (CKD) is associated with increased risk of end stage renal disease and mortality. Falls are a serious negative health outcome in older persons with one third of people aged 65 years experiencing a fall per year and increasing fall rates with increasing age. The impact of CKD on falls in older community-dwelling persons is not well investigated. Additionally, lower urinary tract symptoms (LUTS) may also increase the risk of falls. Therefore, our aim was to investigate the impact of CKD and LUTS on falls as well as on injurious falls. Methods: The SCOPE study is an observational, multinational, multicenter, prospective cohort study involving communitydwelling older persons aged 75 years and more recruited from August 2016 to March 2018 in seven European countries. The main outcomes of the present study were any falls and any injurious falls during the 12 months before enrolment The cross-sectional association of estimated glomerular filtration rate (eGFR) and LUIS with study outcomes was investigated by logistic regression analysis adjusted for baseline characteristics of enrolled subjects. Results: Our series consisted of 2256 SCOPE participants (median age = 795 years, 55.7% female). Of them, 746 participants experienced a fall and 484 reported an injurious fall in the 12 months prior to baseline assessment CKD was not significantly associated with falls (OR = 0.95, 95%CI = 0.79-1.14 for eGFR< 60; OR = 1.02, 95%CI = 0.81-128 for eGFR< 45; OR = 1.08, 95%CI = 0.74-1.57 for eGFR< 30) or injurious falls (OR = 0.91, 95%CI = 0.67-124 for eGFR< 60; OR = 0.93, 95%CI = 0.63-137 for eGFR< 45; OR = 1.19, 95%CI = 0.62-2.29 for eGFR< 30). LUTS were found significantly associated with both falls (OR = 156, 95960 =129-1.89) and injurious falls (OR = 158, 95%0 =1.14-2.19), and such associations were confirmed in all multivariable m
Published: 2020
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97. Clinical Implications of Estimating Glomerular Filtration Rate with Three Different Equations among Older People. Preliminary Results of the Project 'Screening for Chronic Kidney Disease among Older People across Europe (SCOPE)'

Author: Corsonello, Andrea, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Ärnlöv, Johan, Carlsson, Axel C, Tap, Lisanne, Mattace-Raso, Francesco, Formiga, Francesc, Moreno-Gonzalez, Rafael, Weingart, Christian, Sieber, Cornel, Kostka, Tomasz, Guligowska, Agnieszka, Gil, Pedro, Lainez Martinez, Sara, Artzi-Medvedik, Rada, Melzer, Itshak, Lattanzio, Fabrizia, Corsonello, Andrea, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Ärnlöv, Johan, Carlsson, Axel C, Tap, Lisanne, Mattace-Raso, Francesco, Formiga, Francesc, Moreno-Gonzalez, Rafael, Weingart, Christian, Sieber, Cornel, Kostka, Tomasz, Guligowska, Agnieszka, Gil, Pedro, Lainez Martinez, Sara, Artzi-Medvedik, Rada, Melzer, Itshak, and Lattanzio, Fabrizia
Abstract: We aimed at investigating to what extent CKD may be staged interchangeably by three different eGFR equations in older people, and evaluating the source of discrepancies among equations in a population of 2257 patients older than 75 years enrolled in a multicenter observational study. eGFR was calculated by CKD-EPI, BIS and FAS equations. Statistical analysis was carried out by Bland-Altman analysis. kappa statistic was used to quantify the agreement between equations in classifying CKD stages. The impact of selected variables on the difference among equations was graphically explored. The average difference between BIS and FAS was -0.24 (95% limits of agreement (95%LA = -4.64-4.14) mL/min/1.73 m(2). The difference between CKD-EPI and BIS and between CKD-EPI and FAS was 8.97 (95%LA = -2.90-20.84) and 8.72 (95%LA = -2.11-19.56) mL/min/1.73 m(2), respectively. As regards CKD stage classification, kappa value was 0.47 for both CKD-EPI vs. FAS and CKD-EPI vs. BIS, while BIS and FAS had similar classificatory properties (kappa = 0.90). Muscle mass was found related to the difference between CKD-EPI and BIS (R-2 = 0.11) or FAS (R-2 = 0.14), but not to the difference between BIS and FAS. In conclusion, CKD-EPI and BIS/FAS equations are not interchangeable to assess eGFR among older people. Muscle mass may represent a relevant source of discrepancy among eGFR equations.
Published: 2020
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98. Rethinking palliative care in a public health context : addressing the needs of persons with non-communicable chronic diseases

Author: Tziraki, Chariklia, Grimes, Corrina, Ventura, Filipa, O'Caoimh, Ronan, Santana, Silvina, Zavagli, Veronica, Varani, Silvia, Tramontano, Donatella, Apostolo, Joao, Geurden, Bart, De Luca, Vincenzo, Tramontano, Giovanni, Romano, Maria Rosaria, Anastasaki, Marilena, Lionis, Christos, Rodriguez-Acuna, Rafael, Capelas, Manuel Luis, dos Santos Afonso, Tania, Molloy, David William, Liotta, Giuseppe, Iaccarino, Guido, Triassi, Maria, Eklund, Patrik, Roller-Wirnsberger, Regina, Illario, Maddalena, Tziraki, Chariklia, Grimes, Corrina, Ventura, Filipa, O'Caoimh, Ronan, Santana, Silvina, Zavagli, Veronica, Varani, Silvia, Tramontano, Donatella, Apostolo, Joao, Geurden, Bart, De Luca, Vincenzo, Tramontano, Giovanni, Romano, Maria Rosaria, Anastasaki, Marilena, Lionis, Christos, Rodriguez-Acuna, Rafael, Capelas, Manuel Luis, dos Santos Afonso, Tania, Molloy, David William, Liotta, Giuseppe, Iaccarino, Guido, Triassi, Maria, Eklund, Patrik, Roller-Wirnsberger, Regina, and Illario, Maddalena
Abstract: Non-communicable chronic diseases (NCCDs) are the main cause of morbidity and mortality globally. Demographic aging has resulted in older populations with more complex healthcare needs. This necessitates a multilevel rethinking of healthcare policies, health education and community support systems with digitalization of technologies playing a central role. The European Innovation Partnership on Active and Healthy Aging (A3) working group focuses on well-being for older adults, with an emphasis on quality of life and healthy aging. A subgroup of A3, including multidisciplinary stakeholders in health care across Europe, focuses on the palliative care (PC) model as a paradigm to be modified to meet the needs of older persons with NCCDs. This development paper delineates the key parameters we identified as critical in creating a public health model of PC directed to the needs of persons with NCCDs. This paradigm shift should affect horizontal components of public health models. Furthermore, our model includes vertical components often neglected, such as nutrition, resilience, well-being and leisure activities. The main enablers identified are information and communication technologies, education and training programs, communities of compassion, twinning activities, promoting research and increasing awareness amongst policymakers. We also identified key 'bottlenecks': inequity of access, insufficient research, inadequate development of advance care planning and a lack of co-creation of relevant technologies and shared decision-making. Rethinking PC within a public health context must focus on developing policies, training and technologies to enhance person-centered quality life for those with NCCD, while ensuring that they and those important to them experience death with dignity.
Published: 2020
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99. Geriatric intensive care Consensus paper of DGIIN, DIVI, DGAI, DGGG, oGGG, oGIAIN, DGP, DGEM, DGD, DGNI, DGIM, DGKliPha and DGG

Author: Michels, Guido, Sieber, Cornel C., Marx, Gernot, Roller-Wirnsberger, Regina, Joannidis, Michael, Mueller-Werdan, Ursula, Muellges, Wolfgang, Gahn, Georg, Pfister, Roman, Thuermann, Petra A., Wirth, Rainer, Fresenborg, Jana, Kuntz, Ludwig, Simon, Steffen T., Janssens, Uwe, Heppnerz, Hans Juergen, Michels, Guido, Sieber, Cornel C., Marx, Gernot, Roller-Wirnsberger, Regina, Joannidis, Michael, Mueller-Werdan, Ursula, Muellges, Wolfgang, Gahn, Georg, Pfister, Roman, Thuermann, Petra A., Wirth, Rainer, Fresenborg, Jana, Kuntz, Ludwig, Simon, Steffen T., Janssens, Uwe, and Heppnerz, Hans Juergen
Abstract: The proportion of elderly, frail, and multimorbid people has increased dramatically in recent decades resulting from demographic changes and will further increase, which will impact acute medical care. Prospective, randomized studies on geriatric intensive care are still lacking. There are also no international or national recommendations regarding the management of critically ill elderly patients. Based on an expert opinion, this consensus paper provides 16 statements that should be considered when dealing with geriatric critical care patients.
Published: 2020

100. European Collaborative and Interprofessional Capability Framework for Prevention and Management of Frailty-a consensus process supported by the Joint Action for Frailty Prevention (ADVANTAGE) and the European Geriatric Medicine Society (EuGMS).

Author: UCL - SSS/IRSS - Institut de recherche santé et société, Roller-Wirnsberger, Regina, Lindner, Sonja, Liew, Aaron, O'Caoimh, Ronan, Koula, Maria-Lamprini, Moody, Dawn, Espinosa, Juan Manuel, Van Durme, Thérèse, Dimitrov, Plamen, Benjak, Tomislav, Nicolaidou, Elena, Hammar, Teija, Vanhecke, Eliane, Junius-Walker, Ulrike, Csizmadia, Péter, Galluzzo, Lucia, Macijauskienė, Jūratė, Salem, Mohamed, Rietman, Liset, Ranhoff, Anette Hylen, Targowski, Tomasz, de Arriaga, Miguel Telo, Bozdog, Elena, Gabrovec, Branko, Hendry, Anne, Martin, Finbarr C, Rodriguez-Mañas, Leocadio, UCL - SSS/IRSS - Institut de recherche santé et société, Roller-Wirnsberger, Regina, Lindner, Sonja, Liew, Aaron, O'Caoimh, Ronan, Koula, Maria-Lamprini, Moody, Dawn, Espinosa, Juan Manuel, Van Durme, Thérèse, Dimitrov, Plamen, Benjak, Tomislav, Nicolaidou, Elena, Hammar, Teija, Vanhecke, Eliane, Junius-Walker, Ulrike, Csizmadia, Péter, Galluzzo, Lucia, Macijauskienė, Jūratė, Salem, Mohamed, Rietman, Liset, Ranhoff, Anette Hylen, Targowski, Tomasz, de Arriaga, Miguel Telo, Bozdog, Elena, Gabrovec, Branko, Hendry, Anne, Martin, Finbarr C, and Rodriguez-Mañas, Leocadio
Abstract: BACKGROUND: Interprofessional collaborative practice (ICP) is currently recommended for the delivery of high-quality integrated care for older people. Frailty prevention and management are key elements to be tackled on a multi-professional level. AIM: This study aims to develop a consensus-based European multi-professional capability framework for frailty prevention and management. METHODS: Using a modified Delphi technique, a consensus-based framework of knowledge, skills and attitudes for all professions involved in the care pathway of older people was developed within two consultation rounds. The template for the process was derived from competency frameworks collected in a comprehensive approach from EU-funded projects of the European Commission (EC) supported best practice models for health workforce development. RESULTS: The agreed framework consists of 25 items structured in 4 domains of capabilities. Content covers the understanding about frailty, skills for screening and assessment as well as management procedures for every profession involved. The majority of items focused on interprofessional collaboration, communication and person-centred care planning. DISCUSSION: This framework facilitates clarification of professionals' roles and standardizes procedures for cross-sectional care processes. Despite a lack of evidence for educational interventions, health workforce development remains an important aspect of quality assurance in health care systems. CONCLUSIONS: The multi-professional capability framework for frailty prevention and management incorporated interprofessional collaborative practice, consistent with current recommendations by the World Health Organization, Science Advice for Policy by European Academies and the European Commission.
Published: 2020

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