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Li4SiO4 has been widely studied as tritium breeder and high temperature CO2 capture material. Tritium breeding rate and CO2 adsorption capacity are closely related to lithium content and microstructure. Since high sintering temperatures result in grain coarsening and lithium sublimation, it is a great challenge to prepare Li4SiO4 ceramics with a satisfactory mechanical strength at low sintering temperature. In this work, mesoporous silica was used as Si source to prepare Li4SiO4 spheres. The mesoporous structure might provide more reaction sites for lithium ions, thereby facilitating the reaction between LiOH and mesoporous silica. The sintering temperature of Li4SiO4 spheres was greatly reduced by using mesoporous silica as Si source. The Li4SiO4 spheres with a homogenous fine-grained microstructure (the average grain size of 2.2 μm) and high crushing load (41.65N) could be obtained at 675°C.

The power grid is an important connection between power sources and users, responsible for supplying and distributing electric energy to users. Modern power grids are widely distributed and large in scale, and their security faces new problems and challenges. Information entropy theory is an objective weighting method that compares the information order of each evaluation index to judge the weight value. With the wide application of entropy theory in various disciplines, the subject of introducing entropy into the power system has been gradually concerned. This article aims to study the smart terminal security technology of the power grid perception layer based on information entropy data mining. This article analyzes its related methods and designs a smart terminal for the power grid. On this basis, a data analysis platform is built and a safety plan is designed. The result is that the average absolute error, root mean square error, average absolute percentage error, and mean square error of the platform's power load forecast are 1.58, 1.96, 8.2%, and 3.93, respectively. These error values are within the ideal range, and the data processing ability is strong. The packet loss rate of the adversary's eavesdropping was tested, and the average packet loss rates at locations a, b, c, and d were 1.05, 1.2, 1.81, and 2.2%, respectively. Data packets will be definitely lost, so the platform is highly secure.

Background: Currently, adequate treatment and prognostic prediction means for Hepatocellular Carcinoma (HCC) haven't entered into medical vision. Tanshinone IIA (TanIIA) is a natural product, which can be utilized as a potential treatment of HCC due to its high anti-tumor activity. However, the effect on HCC prognosis, as well as the potential targets and molecular mechanism of TanIIA still remain ambiguous. Herein, we investigated them via network pharmacology, explored TanIIA-related prognostic genes by machine learning methods, and verified using molecular docking and cell experiments. Methods: Potential TanIIA-targeted genes and HCC-related genes were obtained from the corresponding database. The Protein-Protein Interaction (PPI) network and enrichment analyses of the intersection targets were conducted. Furthermore, a TanIIA-related prognostic model was built and verified. We attempted to explore the expression of the TanIIA-related prognostic genes and evaluate its chemotherapeutic sensitivities and the immune infiltrations. Followed by exploration of anti-tumor activity on the human HCC cells Hep3B and HepG2 cell lines in vitro (CCK-8, flow cytometry and transwell assay), the docking molecular was performed. Ultimately, the corresponding protein expressions were determined by western blotting. Results: A total of 64 intersecting targets were collected. Similarly, GO/KEGG enrichment analysis showed that TanIIA can inhibit HCC by affecting multiple pathways, especially the MAPK signaling pathway. A five-gene signature related to TanIIA was constructed on account of Least Absolute Shrinkage and Selection Operator (LASSO) Cox regression model. Among five genes, ALB, ESR1 and SRC tend to be core genes because of probable status as potential targets for sorafenib. Molecular docking results demonstrated the potential for active interaction between the core genes relevant proteins and TanIIA. Studies in vitro had shown that TanIIA regulated the expressions of Bcl-2, Bax and MMP9 in HCC cells, inhibiting their growth, inducing apoptosis and preventing cell invasion. Additionally, we are able to detect an up-regulated trend in the expression of ALB and ESR1, while a down-regulated in the expression of SRC by TanIIA. Conclusion: Regulating the expression of TanIIA-related gene signatures (ALB, SRC and ESR1), and inhibiting the SRC/MAPK/ERK signaling axis might potentially contribute to the TanIIA treatment of HCC. And the three gene signatures could be identified for predicting the prognosis of HCC, which may provide novel biomarkers for HCC treatment. [ABSTRACT FROM AUTHOR]

The highly ordered film assembled by regularly 1D nanostructures has potential prospects in electronic, photoelectronic and other fields because of its excellent light‐trapping effect and electronic transport property. However, the controlled growth of highly ordered film remains a great challenge. Herein, large‐area and highly ordered Bi2S3 film is synthesized on fluorophlogopite mica substrate by chemical vapor deposition method. The Bi2S3 film features hollowed‐out crosslinked network structure, assembled by 1D nanobelts that regularly distribute in three orientations, which agrees well with the first principles calculations. Based on the as‐grown Bi2S3 film, the broadband photodetector with a response range from 365 to 940 nm is fabricated, exhibiting a maximum responsivity up to 98.51 mA W–1, specific detectivity of 2.03 × 1010 Jones and fast response time of 35.19 ms. The stable instantaneous on/off behavior for 500 cycles and reliable photoresponse characteristics of the Bi2S3 photodetector after storage in air for 6 months confirm its excellent long‐term stability and air stability. Significantly, as sensing pixel and signal receiving terminal, the device successfully achieves high‐resolution imaging of characters of "H", "I" and "T", and secure transmission of confidential information. This work shows a great potential of the large‐area and highly ordered Bi2S3 film toward the development of future multiple functional photoelectronic applications. [ABSTRACT FROM AUTHOR]