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628 results on '"Rashidi, Ali"'

51. Angiosarcoma on Top of a Meningioma Mimicking a Transosseous Meningioma: an Interdisciplinary Point of View.

Author

Kohl, Jana, König, Rebecca E, Kraus, Armin, Mawrin, Christian, Paukisch, Harald, Stein, Klaus-Peter, Rashidi, Ali, Luchtmann, Michael, Sandalcioglu, I Erol, and Lilla, Nadine

Subjects
MENINGIOMA, SKIN tumors, INTRACRANIAL tumors, BENIGN tumors, ANGIOSARCOMA, SKIN biopsy
Abstract

Cutaneous angiosarcoma is a rare type of sarcoma with poor prognosis. Meningioma is the most frequent benign intracranial tumor. Despite the fact that meningiomas are mostly benign, bone and skin can be infiltrated. We report the rare case of an angiosarcoma on top of a meningioma with hyperostosis at exactly the same location mimicking a transosseous growth of a meningioma. An 84-year-old man presented with progressive swelling and ulcerous lesion of the forehead. The patient underwent surgery in an interdisciplinary setting together with a plastic surgeon, including resection of the intracranial tumor and infiltrated bone and skin. To the best of our knowledge, this is the only reported case of a meningioma and angiosarcoma in direct neighborhood. A preoperative biopsy of the skin tumor would have led initially to the correct diagnosis of an angiosarcoma and would have allowed a better planning of the operation and extent of resection. [ABSTRACT FROM AUTHOR]

Published
2024
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66. The Roles of AGTRAP, ALKBH3, DIVERSIN, NEDD8 and RRM1 in Glioblastoma Pathophysiology and Prognosis.

Author

Dumitru, Claudia Alexandra, Walter, Nikolas, Siebert, Carl Ludwig Raven, Schäfer, Frederik Till Alexander, Rashidi, Ali, Neyazi, Belal, Stein, Klaus-Peter, Mawrin, Christian, and Sandalcioglu, Ibrahim Erol

Subjects
PROPORTIONAL hazards models, OVERALL survival, PROGRESSION-free survival, PROGNOSIS, GLIOBLASTOMA multiforme
Abstract

This study determined the expression of five novel biomarker candidates in IDH wild-type glioblastoma (GBM) tissues compared to non-malign brain parenchyma, as well as their prognostic relevance for the GBM patients' outcomes. The markers were analysed by immunohistochemistry in tumour tissues (n = 186) and healthy brain tissues (n = 54). The association with the patients' overall survival (OS) and progression-free survival (PFS) was assessed by Kaplan–Meier and log-rank test. The prognostic value of the markers was determined using multivariate Cox proportional hazard models. AGTRAP, DIVERSIN, cytoplasmic NEDD8 (NEDD8c) and RRM1 were significantly overexpressed in tumour tissues compared to the healthy brain, while the opposite was observed for ALKBH3. AGTRAP, ALKBH3, NEDD8c and RRM1 were significantly associated with OS in univariate analysis. AGTRAP and RRM1 were also independent prognostic factors for OS in multivariate analysis. For PFS, only AGTRAP and NEDD8c reached significance in univariate analysis. Additionally, AGTRAP was an independent prognostic factor for PFS in multivariate models. Finally, combined analysis of the markers enhanced their prognostic accuracy. The combination AGTRAP/ALKBH3 had the strongest prognostic value for the OS of GBM patients. These findings contribute to a better understanding of the GBM pathophysiology and may help identify novel therapeutic targets in this type of cancer. [ABSTRACT FROM AUTHOR]

Published
2024
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70. List of contributors

Author

Beyer, Günter, primary, Cavallaro, Giuseppe, additional, Chiappisi, Leonardo, additional, Dana, Kausik, additional, de Melo Barbosa, Raquel, additional, Ferreira, Marianna Araújo, additional, Guan, Huijuan, additional, Kausar, Ayesha, additional, Lazzara, Giuseppe, additional, Lisuzzo, Lorenzo, additional, Massaro, Marina, additional, Meirelles, Lyghia Maria Araújo, additional, Milioto, Stefana, additional, Otazaghine, Belkacem, additional, Parisi, Filippo, additional, Pasbakhsh, Pooria, additional, Raffin, Fernanda Nervo, additional, Rashidi, Ali, additional, Riela, Serena, additional, Sadjadi, Samahe, additional, Saeb, Mohammad Reza, additional, Sarkar, Madhuchhanda, additional, Scholtzová, Eva, additional, Solanki, Nishal Ashvin, additional, Sonnier, Rodolphe, additional, Taguet, Aurélie, additional, Trusilewicz, Lidia Natalia, additional, Vahabi, Henri, additional, Villanova-de-Benavent, Cristina, additional, Zhao, Yafei, additional, and Zorato, Nicole, additional

Published
2020
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75. Development of citation measures and the socio-cultural factors affecting citation behavior in an emerging scientific community

Author

Rashidi, Ali

Subjects
020, 020 Library & information sciences
Abstract

This thesis presents the development of theoretical and empirically applied citation_based bibliometric indicators of scientific research performance and applies them to Iranian medical research. In the absence of any pre-existing bibliometric data to provide objective indices to aid decision-making processes, a new body of information related to medical journals publications in Iran was manually collected. A database of all articles 10876) in the 90 Iranian medical journals published from 2002 to 2004 was developed and populated and used as a basis for comprehensive analysis of bibliometric indicators of Iranian medical publications. One of the outcomes of the citation analysis was discovering that there is an unexpectedly low rate of citation to internally published articles. To seek possible reasons for this, a survey analysis of the cultural and social factors influencing citation behaviour of Iranian medical scholars was undertaken. Further analysis revealed that the Garfield (ISI) impact factor was not an effective tool for making decisions regarding subject specific collections. Although previous authors have alluded to this drawback, the solutions were often too complex for them to be used by librarians. To address these shortcomings, two new practical measures (Indices) have been developed. The DSI supports individual subscription decisions with regard to the level of specialism of a journal within a particular discipline. DPI is a decision-making tool for libraries that indicates the proportion of all citations within a particular discipline that had been received by a particular journal. Iranian medical researchers' relationship with international journals was further considered by investigating the rate of publication of articles by these researchers in two different databases (Science Citation Index and PubMed) from 2002 to 2004. In addition, to allow medical librarians in Iran to make more informed procurement choices with regard to internationally published journals, data were gathered to determine the extent to which Iranian medical researchers use them. Finally, based on the experiences obtained from the empirical data collection, the findings from data analysis and the responses from the survey analysis, a number of policy recommendations and suggestions for taking these ideas further are proposed.

Published
2009

85. Fight INflammation to Improve outcome after aneurysmal Subarachnoid HEmorRhage (FINISHER) trial: Study protocol for a randomized controlled trial

Author

Gueresir, Erdem, Lampmann, Tim, Bele, Sylvia, Czabanka, Marcus, Czorlich, Patrick, Gempt, Jens, Goldbrunner, Roland, Hurth, Helene, Hermann, Elvis, Jabbarli, Ramazan, Krauthausen, Marius, Koenig, Ralph, Lindner, Dirk, Malinova, Vesna, Meixensberger, Jurgen, Mielke, Dorothee, Nemeth, Robert, Oppong, Marvin Darkwah, Pala, Andrej, Prinz, Vincent, Rashidi, Ali, Roder, Constantin, Sandalcioglu, Ibrahim Erol, Sauvigny, Thomas, Schebesch, Karl-Michael, Timmer, Marco, Vajkoczy, Peter, Wessels, Lars, Wild, Florian, Wilhelm, Christoph, Wostrack, Maria, Vatter, Hartmut, Coch, Christoph, Gueresir, Erdem, Lampmann, Tim, Bele, Sylvia, Czabanka, Marcus, Czorlich, Patrick, Gempt, Jens, Goldbrunner, Roland, Hurth, Helene, Hermann, Elvis, Jabbarli, Ramazan, Krauthausen, Marius, Koenig, Ralph, Lindner, Dirk, Malinova, Vesna, Meixensberger, Jurgen, Mielke, Dorothee, Nemeth, Robert, Oppong, Marvin Darkwah, Pala, Andrej, Prinz, Vincent, Rashidi, Ali, Roder, Constantin, Sandalcioglu, Ibrahim Erol, Sauvigny, Thomas, Schebesch, Karl-Michael, Timmer, Marco, Vajkoczy, Peter, Wessels, Lars, Wild, Florian, Wilhelm, Christoph, Wostrack, Maria, Vatter, Hartmut, and Coch, Christoph

Abstract

Rationale: Aneurysmal subarachnoid hemorrhage (SAH) has high morbidity and mortality. While the primary injury results from the initial bleeding cannot currently be influenced, secondary injury through vasospasm and delayed cerebral ischemia worsens outcome and might be a target for interventions to improve outcome. To date, beside the aneurysm treatment to prevent re-bleeding and the administration of oral nimodipine, there is no therapy available, so novel treatment concepts are needed. Evidence suggests that inflammation contributes to delayed cerebral ischemia and poor outcome in SAH. Some studies suggest a beneficial effect of anti-inflammatory glucocorticoids, but there are no data from randomized controlled trials examining the efficacy of glucocorticoids. Therefore, current guidelines do not recommend the use of glucocorticoids in SAH. Aim: The Fight INflammation to Improve outcome after aneurysmal Subarachnoid HEmorRhage (FINISHER) trial aims to determine whether dexamethasone improves outcome in a clinically relevant endpoint in SAH patients. Methods and design: FINISHER is a multicenter, prospective, randomized, double-blinded, placebo-controlled clinical phase III trial which is testing the outcome and safety of anti-inflammatory treatment with dexamethasone in SAH patients. Sample size estimates: In all, 334 patients will be randomized to either dexamethasone or placebo within 48 h after SAH. The dexamethasone dose is 8 mg tds for days 1-7 and then 8 mg od for days 8-21. Study outcome: The primary outcome is the modified Rankin Scale (mRS) at 6 months, which is dichotomized to favorable (mRS 0-3) versus unfavorable (mRS 4-6). Discussion: The results of this study will provide the first phase III evidence as to whether dexamethasone improves outcome in SAH.

Published
2023

94. MegaPro, a clinically translatable nanoparticle for in vivo tracking of stem cell implants in pig cartilage defects

Author

Suryadevara, Vidyani, primary, Hajipour, Mohammad Javad, additional, Adams, Lisa C., additional, Aissaoui, Nour Mary, additional, Rashidi, Ali, additional, Kiru, Louise, additional, Theruvath, Ashok J., additional, Huang, Ching‐Hsin, additional, Maruyama, Masahiro, additional, Tsubosaka, Masanori, additional, Lyons, Jennifer K., additional, Wu, Wei (Emma), additional, Roudi, Raheleh, additional, Goodman, Stuart B., additional, and Daldrup‐Link, Heike E., additional

Published
2023
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