315 results on '"Radominska-Pandya, Anna"'
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52. Special issue: Nanotechnology and Disease
53. Novel Resveratrol-Based Substrates for Human Hepatic, Renal, and Intestinal UDP-Glucuronosyltransferases
54. Sulfaphenazole and α-Naphthoflavone Attenuate the Metabolism of the Synthetic Cannabinoids JWH-018 and AM2201 Found in K2/Spice
55. CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen
56. Targeted Metabolomic Approach for Assessing Human Synthetic Cannabinoid Exposure and Pharmacology
57. Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
58. Cytochrome P450-Mediated Oxidative Metabolism of Abused Synthetic Cannabinoids Found in K2/Spice: Identification of Novel Cannabinoid Receptor Ligands
59. Role of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311: Highly Selective Substrates for UGT1A10
60. Glucuronides of antitumor agents C‐1311 and C‐1305 modulate cytotoxicity in cancer cells
61. Functionalized‐single‐walled nanotube (f‐SWNT)‐assisted in vitro delivery of the oncogene suppressor genes to cancer cells
62. A Major Glucuronidated Metabolite of JWH-018 Is a Neutral Antagonist at CB1 Receptors
63. Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors
64. Analysis of R- and S-Hydroxywarfarin Glucuronidation Catalyzed by Human Liver Microsomes and Recombinant UDP-Glucuronosyltransferases
65. Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells
66. Solid-Phase Extraction and Quantitative Measurement of Omega and Omega-1 Metabolites of JWH-018 and JWH-073 in Human Urine
67. Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
68. Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine
69. Human UDP‐glucuronosyltransferases (UGTs) are involved in the metabolism of the natural resveratrol analogues arachidin‐1, arachidin‐3 and piceatannol
70. Targeted nanoparticle delivery of tumor suppressing UDP‐glucuronosyltransferase (UGT) genes into cancer cells
71. The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families
72. Erratum to “Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues” [Steroids 73 (6) (2008) 611–620]
73. Assessing Cytochrome P450 and UDP-Glucuronosyltransferase Contributions to Warfarin Metabolism in Humans
74. Characterization of mutation in the 395 DQxD 398 motif of the glucuronic acid binding site in human UGT1A6: Comparison to UGT1A10
75. The glucuronidation of native and oxidized estrogens can be effectively inhibited by compounds structurally related to UDP‐glucuronic acid in human recombinant UGT1A10
76. Comparative characterization of UDP‐glucuronic acid (UDP‐GlcUA) binding‐site directed inhibitors with human UGT2B7 and 1A10.
77. Dopamine Is a Low-Affinity and High-Specificity Substrate for the Human UDP-Glucuronosyltransferase 1A10
78. Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
79. Human hepatic and extrahepatic UDP‐glucuronosyltransferase (UGTs) enzymes involved in the metabolism of cannabinoids
80. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
81. Glucuronidation of Monohydroxylated Warfarin Metabolites by Human Liver Microsomes and Human Recombinant UDP-Glucuronosyltransferases
82. Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7
83. CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling
84. Aspartic Acid 393 of the DxxD Motif within The C‐Terminal Region of Human UDP‐Glucuronosyltransferase 1A10 is Critical to the Binding of UDP‐Glucuronic Acid
85. Glucuronidation of Warfarin Metabolites by Human Recombinant UDP‐Glucuronosyltransferases (UGTs)
86. Sulfation of the Isoflavones Genistein and Daidzein in Human and Rat Liver and Gastrointestinal Tract
87. Phe90 is a crucial amino acid within the estrogen binding site of the human UDP‐glucuronosyltransferase 1A10
88. Characterization of UDP‐glucuronosyltransferases in normal and carcinogenic human breast tissue
89. Phenylalanine 90 and 93 Are Localized within the Phenol Binding Site of Human UDP-Glucuronosyltransferase 1A10 as Determined by Photoaffinity Labeling, Mass Spectrometry, and Site-Directed Mutagenesis
90. Human UDP-Glucuronosyltransferase 1A5: Identification, Expression, and Activity
91. LITHOCHOLIC ACID DECREASES EXPRESSION OF UGT2B7 IN CACO-2 CELLS: A POTENTIAL ROLE FOR A NEGATIVE FARNESOID X RECEPTOR RESPONSE ELEMENT
92. A Historical Overview of the Heterologous Expression of Mammalian UDP-Glucuronosyltransferase Isoforms Over the Past Twenty Years
93. Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract
94. Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases
95. HUMAN PXR VARIANTS AND THEIR DIFFERENTIAL EFFECTS ON THE REGULATION OF HUMAN UDP-GLUCURONOSYLTRANSFERASE GENE EXPRESSION
96. Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7
97. Interindividual variation and organ-specific patterns of glutathione S-transferase alpha, mu, and pi expression in gastrointestinal tract mucosa of normal individuals
98. Critical Role of Diacylglycerol- and Phospholipid-Regulated Protein Kinase Cε in Induction of Low-Density Lipoprotein Receptor Transcription in Response to Depletion of Cholesterol
99. Glucuronidation of the Dietary Fatty Acids, Phytanic Acid and Docosahexaenoic Acid, by Human UDP-Glucuronosyltransferases
100. Photoaffinity Labeling of Human Retinoid X Receptor β (RXRβ) with 9-cis-Retinoic Acid: Identification of Phytanic Acid, Docosahexaenoic Acid, and Lithocholic Acid as Ligands for RXRβ
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