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Your search keyword '"Provenzano, L"' showing total 238 results
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238 results on '"Provenzano, L"'

55. Poem Versus Laparoscopic Heller Myotomy in the Treatment of Esophageal Achalasia: A Case-Control Study from Two High Volume Centers Using the Propensity Score

Author

Costantini, A., Familiari, Pietro, Costantini, M., Salvador, R., Valmasoni, M., Capovilla, G., Landi, Rosario, Mangiola, Francesca, Provenzano, L., Briscolini, D., Merigliano, S., Costamagna, Guido, Familiari P. (ORCID:0000-0002-5181-2928), Landi R., Mangiola F., Costamagna G. (ORCID:0000-0002-8100-2731), Costantini, A., Familiari, Pietro, Costantini, M., Salvador, R., Valmasoni, M., Capovilla, G., Landi, Rosario, Mangiola, Francesca, Provenzano, L., Briscolini, D., Merigliano, S., Costamagna, Guido, Familiari P. (ORCID:0000-0002-5181-2928), Landi R., Mangiola F., and Costamagna G. (ORCID:0000-0002-8100-2731)

Abstract

Background: POEM has recently had a widespread diffusion, aiming at being the treatment of choice for esophageal achalasia. The results of ongoing RCTs against laparoscopic myotomy are not available, yet. We, therefore, designed this propensity score (PS) case-control study with the aim of evaluating how POEM compares to the long-standing laparoscopic Heller myotomy + Dor fundoplication (LHD) and verifying if it may really replace the latter as the first-line treatment for achalasia. Methods: Two groups of consecutive patients undergoing treatment for primary achalasia from January 2014 to November 2017 were recruited in two high-volume centers, one with extensive experience with POEM and one with LHD. Patients with previous endoscopic treatment were included, whereas patients with previous LHD or POEM were excluded. A total of 140 patients in both centers were thus matched. LHD and POEM were performed following established techniques. The patients were followed with clinical (Eckardt score), endoscopic, and pH-manometry evaluations. Results: The procedure was successfully completed in all the patients. POEM required a shorter operation time and postoperative stay compared to LHD (p < 0.001). No mortality was recorded in either group. Seven complications were recorded in the POEM group (five mucosal perforations) and 3 in the LHD group (3 mucosal perforations)(p = 0.33). Two patients in the POEM group and one in the LHD were lost to follow-up. One patient in both groups died during the follow-up for unrelated causes. At a median follow-up of 24 months [15–30] for POEM and 31 months [15–41] for LHD (p < 0.05), 99.3% of the POEM patients and 97.7% of the LHD patients showed an Eckardt score ≤ 3 (p < 0.12). Four years after the treatment, the probability to have symptoms adequately controlled was > 90% for both groups (p = 0.2, Log-rank test). HR-Manometry showed a similar reduction in the LES pressure and 4sIRP; 24-h pH-monitoring showed however an abnorma

Published
2020

62. Photon iso-effective dose for cancer treatment with mixed field radiation based on dose–response assessment from human and an animal model: clinical application to boron neutron capture therapy for head and neck cancer

Author

González, S J, primary, Pozzi, E C C, additional, Monti Hughes, A, additional, Provenzano, L, additional, Koivunoro, H, additional, Carando, D G, additional, Thorp, S I, additional, Casal, M R, additional, Bortolussi, S, additional, Trivillin, V A, additional, Garabalino, M A, additional, Curotto, P, additional, Heber, E M, additional, Santa Cruz, G A, additional, Kankaanranta, L, additional, Joensuu, H, additional, and Schwint, A E, additional

Published
2017
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92. Computer-based simulator for catheter insertion training

Author

Giovanni Aloisio, Barone L, Bergamasco M, Ca, Avizzano, Lt, Paolis, Franceschini M, Mongelli A, Pantile G, Provenzano L, Raspolli M, Aloisio, Giovanni, Barone, L, Bergamasco, M, Avizzano, Ca, DE PAOLIS, Lucio Tommaso, Franceschini, M, Mongelli, Antonio, Pantile, G, Provenzano, L, and Raspolli, M.

93. Epilessia un approccio interdisciplinare

Author

Colicchio, Gabriella, Bertola, A, Gentilomo, A, Pinkus, L, Provenzano, L, and Scerrati, M.

Subjects
Epilessia, Settore MED/27 - NEUROCHIRURGIA
Published
1981

95. HERMES system: A virtual reality simulator for the angioplasty intervention training

Author

Aloisio, G., Lucio Tommaso De Paolis, Provenzano, L., Colizzi, L., and Pantile, G.

Subjects
ComputingMethodologies_COMPUTERGRAPHICS
Abstract

One of the essential requirements in order to have a realistic surgical simulator is real-time interaction by means of a haptic interface is. In fact, reproducing haptic sensations increases the realism of the simulation. However, the interaction need to be performed in real-time, since a delay between the user action and the system reaction reduces the user immersion. In this paper, we present a prototype of the coronary stent implant simulator developed in the HERMES Project; this system allows real-time interactions with a artery by means of a specific haptic device; thus the user can interactively navigate in a reconstructed artery and force feedback is produced when contact occurs between the artery walls and the medical instruments

96. Searching for a specific virtual environment for an angioplasty training simulator

Author

Aloisio, G., Lucio Tommaso De Paolis, Provenzano, L., Aloisio, Giovanni, DE PAOLIS, Lucio Tommaso, and Provenzano, Luciana

Abstract

Many minimally invasive procedures need to be learned by repetition whilst avoiding risk for real patients. Virtual reality technology brings numerous advantages to the medical community making it possible to build surgical training simulators which offer hospitals a means of improving training and reducing the costs of education. It is very important to carry out the same surgical procedure on a variety of different case studies. This paper presents a prototype of a coronary stent implant simulator and a 3-tier architecture, able to look for a virtual environment with specific features in terms of pathology or anatomy. The simulator permits real-time interactions with a deformable artery and is provided with a specific haptic device. The virtual environment is built from real patients’ images and by means of a Web Portal it is possible, using data from many medical centres, to search for virtual environments which differ in terms of the pathology, the anatomical structure and the patient’s age, so that they correspond to several virtual patients, each of them exhibiting a particular difficulty. The search for the desired virtual environment is based on the descriptive information (metadata) stored with the virtual environments on databases present in the medical centres. After downloading and integration of the desired virtual environment in the training centre it is possible to carry out training on the cathetering procedure.

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